R-454B  R-454B, formerly known as DR-5A, and sold under the trademarked name Opteon, is a refrigerant. R-454B has characteristics that reduce greenhouse effects and global warming impacts. It is intended to replace the older environmentally-friendly R-410A refrigerant. R-454B was first produced around 2010, and is manufactured by Chemours. As of 2018, it is not yet manufactured in commercial quantities, but efforts are underway to use it commercially.