Lamb led excavations on this site from 1929 to 1933, largely funded at her own expense, discovering a series of prehistoric settlements. She visited the archaeological excavation of Troy in 1930 and 1932, which inspired further work, allowing her to associate Thermi towns IV and V with Troy IIa, and gave a lecture, expanding on these views, as part of the 1936 exhibition at the Royal Academy of Arts on "British Archaeological Discoveries in Greece and Crete 1886–1936". Lamb published her results from Thermi as a book in 1936 – for which she was awarded a Doctor of Science degree from Cambridge in 1940, examined by V. Gordon Childe and Carl Blegen – and provided a selection of finds from the dig to the Fitzwilliam Museum's prehistoric gallery. She subsequently conducted excavations at Antissa (1931–33; also on Lesbos), where she discovered prehistoric, archaic, classical, and Hellenistic settlements and burials, and at the archaic sanctuary of Apollo Phanaios at Kato Phano on Chios (1934). Lamb's archaeological work on Lesbos had focused on links between Thermi and Troy; after this, she turned her attention to ancient Anatolia (modern Turkey), following in the footsteps of other women archaeologists, including Gertrude Bell, Margaret Hardie, and Dorothy Lamb (no relation), who had excavated there before the war. Lamb selected the site of Kusura, conducting a trial excavation in 1935 with Elinor W. Gardner and full excavations in 1936 and 1937 with James Rivers Barrington Stewart, Eleanor Mary Barrington Stewart, Rachel Maxwell-Hyslop, R.H. Macartney, and Nine Six; as well as excavating the cemetery, finds included a cult site and pottery relating to Troy VI. Lamb presented her findings in a lecture to the Society of Antiquaries in London on 'Recent developments in the prehistory of Anatolia' in 1937, pointing out Kusura's location on a major Bronze Age route between central Anatolia and the Aegean. A second lecture to the Society of Antiquaries in 1938 similarly emphasized Kusura's relationships with both of these areas. Lamb also published the Anatolian material held by the Fitzwilliam Museum. She felt that more excavation was required in Anatolia, but her work was interrupted by the outbreak of World War II. Lamb was a founding member of the British Institute of Archaeology at Ankara, whose creation was initiated in 1946 by John Garstang, and served as its honorary secretary from its formal opening in 1948 until 1957, when she resigned from this role and took on the position of vice president.