The species tends to grow in rainforest zones that are clearly defined and in altitudes up to . It often occurs in areas with a strong seasonal climate with a wide-ranging mean annual temperature and with a mean annual rainfall ranging from . It occurs in brushwood, thickets, hedges, teak forest and grassland and generally takes to poorer quality clay soils or deep and sandy soils with a wide pH range. In India, it can occur in dry deciduous forest. In southern Africa, "Dichrostachys cinerea" generally flowers from October to February with fruiting from May to September. In Indonesia, however, the species has been found flowering from September to June and fruiting from March to May. The tree generally grows at a medium to slow rate, per year. Fruit and seeds that grow on "Dichrostachys cinerea" are edible. Cattle, camels and game such as giraffe, buffalo, kudu, hartebeest, nyala, red forest duiker and Damara dik-dik feed on the juicy pods that fall to the ground. Such animals also feed on the immature twigs and leaves of the tree which are rich in protein (11–15%) and minerals. The flowers can be a valuable source of honey. The wood is of a dense nature and burns slowly with no toxicity, so it is often used for fuelwood. The species yields a medium to heavy, durable hardwood and is often used in smaller domestic items as walking sticks, handles, spears and tool handles, particularly in central Africa. In traditional medicine, the bark is used for headache, toothache, dysentery, elephantiasis, root infusions are used for leprosy, syphilis, coughs, as an anthelmintic, purgative and strong diuretic, leaves are used for epilepsy and also as a diuretic and laxative, and a powdered form is massaged on limbs with bone fractures. The roots are also sometimes used for bites or stings. In Siddha medicine of the Tamils in southern India, "Dichrostachys cinerea" is called "vidathther" and used for gonorrhea, syphilis and eczema. As they are rich in nutrients, the plants are often used as fertiliser, particularly in the Sahel region of Africa along riverbanks. The plant is widely used for soil conservation, particularly in India, for shallow soils, and in arid western and subhumid alluvial plains.