Russian champions CSKA Moscow returned to the Final Four to make it their eight consecutive Final Four appearance. The club beat Kirolbet Baskonia 3–1 in the play-offs. Defending Euroleague and spanish champions Real Madrid would play its third consecutive Final Four appearance. The match would be a re-match of the 2018 Semifinal A, which Real Madrid won on their way to their 10th title. Real Madrid beat Panathinaikos OPAP 3–0 in the play-offs. Fenerbahçe and Real Madrid faced off in a re-match of the 2018 championship game. Facundo Campazzo set an all-time record for assists in a Final Four game, with 15. He surpassed Terrell McIntyre's record from 2008. The seven-time EuroLeague champions CSKA Moscow advanced to the championship game for the seventh time and first since 2016 EuroLeague Final Four. Anadolu Efes advance to the Final Four Championship Game for the first time in their history, having finished third in both previous Euroleague Final Four participations. Remarkable was that in the previous season, Efes finished sixteenth and last in the EuroLeague. Shane Larkin broke the record for most points scored in a Final Four, with 59 total.