He was often referred to by Simpson as his "main man" and was the leader of the team's "Electric Company" which "turned on the Juice". McKenzie also played for the Seattle Seahawks (1983-1984). In his 13-year NFL career, he appeared in 171 games, 169 as a starter. After retiring from football, McKenzie established Reggie McKenzie Industrial Materials, an industrial products company based in Livonia, Michigan. He is also the founder of the Reggie McKenzie Foundation, an organization that helps Detroit youth with athletics and academics. In 2002, McKenzie was inducted into the College Football Hall of Fame. He was also inducted into the Michigan Sports Hall of Fame in 1994. He was inducted into the Greater Buffalo Sports Hall of Fame in 2016. On November 22, 2016, McKenzie won the Big Ten's Ford-Kinnick Leadership Award.