Both skeletons are currently housed in the Sternberg Museum of Natural History. In 1968, a collector named Tim Basgall discovered another notable skeleton that, similar to FHSM VP-2187, also consisted of a near-complete vertebral column and a partially preserved skull. This fossil is housed in the University of Kansas Museum of Natural History as KUVP 69102. In 1958, Soviet paleontologist Leonid Glickman found that the dental design of "O. mantelli" reconstructed by Eastman made it distinct enough to warrant a new genus—"Cretoxyrhina". He also identified a second species of "Cretoxyrhina" based on some of the earlier "Cretoxyrhina" teeth, which he named "Cretoxyrhina denticulata". Originally, Glickman designated "C. mantelli" as the type species, but he abruptly replaced the position with another taxon identified as " 'Isurus denticulatus' " without explanation in a 1964 paper, a move now rejected as an invalid taxonomic amendment. This nevertheless led Russian paleontologist Viktor Zhelezko to erroneously invalidate the genus "Cretoxyrhina" in a 2000 paper by synonymizing " 'Isurus denticulatus' " (and thus the genus "Cretoxyrhina" as a whole) with another taxon identified as " 'Pseudoisurus tomosus"'. Zhelezko also described a new species congeneric with "C. mantelli" based on tooth material from Kazakhstan, which he identified as "Pseudoisurus vraconensis" accordingly to his taxonomic reassessment. A 2013 study led by Western Australian Museum curator and paleontologist Mikael Siverson corrected the taxonomic error, reinstating the genus "Cretoxyrhina" and moving " 'P'. vraconensis" into it. In 2010, British and Canadian paleontologists Charlie Underwood and Stephen Cumbaa described "Telodontaspis agassizensis" from teeth found in Lake Agassiz in Manitoba that were previously identified as juvenile "Cretoxyrhina" teeth. This species was reaffirmed into the genus "Cretoxyrhina" by a 2013 study led by American paleontologist Michael Newbrey using additional fossil material of the same species found in Western Australia. Between 1997 and 2008, paleontologist Kenshu Shimada published a series of papers where he analyzed the skeletons of "C. mantelli" including those found by the Sternbergs using modernized techniques to extensively research the possible biology of "Cretoxyrhina".