This physician's handbook had 10 more editions in his lifetime and established Joslin as a world leader in diabetes. Two years later, Joslin wrote "Diabetic Manual — for the Doctor and Patient", detailing what patients could do to take control of their disease. This was the first diabetes patient handbook and became a best seller. There have been 14 editions of this pioneering handbook, and a version is still published today by the Joslin Diabetes Center under the title "The Joslin Guide to Diabetes." When insulin became available as therapy in 1922, Joslin's corps of nurses became the forerunners of certified diabetes educators, providing instruction in diet, exercise, foot care and insulin dosing, and established camps for children with diabetes throughout New England. With insulin available, Joslin enlarged his medical practice into a team that evolved into the Joslin Clinic, which was affiliated with the New England Deaconess Hospital and the Harvard Medical School. Joslin's associates were chosen to expand his interests in foot salvage for the middle aged diabetic prone to peripheral vascular disease as well as group education for diabetics in the hospital setting. This later expanded to include the first nurse educator service and children's diabetic camps. His proteges, including Drs. Alexander Marble and Priscilla White, followed his mandate to investigate problems in diabetes and metabolism. Marble became Joslin's first research director, and White created the first "high risk" pregnancy clinic aimed at improving outcomes for infants and the insulin-dependent woman during pregnancy and at delivery. The first hospital blood glucose monitoring system for pre-meal testing was developed under Joslin's direction before 1940 and was the forerunner of the modern glucometer era. Joslin was also the first to name diabetes a serious public health issue. Just after WWII, he expressed concern to the Surgeon General of the U.S. Public Health Service that diabetes was an epidemic, and challenged the government to do a study in his hometown, Oxford, Massachusetts. The study was started in 1946 and soon confirmed the true incidence of diabetes in the general population (including a percentage of cases that went undetected). The study was carried out over the next 20 years. The results would later confirm Joslin's fear that the incidence of diabetes in the United States was approaching epidemic proportions. He has been named as being, with Frederick Madison Allen, one of the two leading diabetologists from the period between 1910 and 1920. In 1952, Joslin's group practice became officially known as the Joslin Clinic. In 1956, the office moved to its current location at One Joslin Place in Boston.