The third round featured the six winning teams from the second round and the 14 teams from Ligue 1 who didn't qualify for European competition this season. The matches were played on 21–22 September 2010. Source: Ligue de Football Professionnel  The draw for the Round of 16 of the 2010–11 edition of the Coupe de la Ligue was held on 28 September 2010. The round featured the ten winning teams from the third round and the six teams that qualified for European competition in the 2009–10 season. The matches were played on 26–27 October. Source: Ligue de Football Professionnel  Note: Players marked in bold are still playing in the competition.