After returning to Quetta he served a second term as the Vice Chairman of BSO from 1978 to 1980 and while he managed to secure a job as a Mining Engineer in a private mining company, his political life remained dominant over his professional life. So much so, in fact, that he eventually quit his job to devote all his time and energy to politics. After serving his second term as the Vice Chairman of BSO, he joined the political party of Ghaus Bakhsh Bizenjo, The Pakistan National Party. After Mir Ghaus Bakhsh's death in August 1989, the leadership of the party shifted to Mir Bizen Bizenjo but he wasn't able to hold on to it for long. When Mir Bizen vacated the office of the Party President, PNP was thrown into turmoil. During this tumultuous time the position of Party Organizer was also vacant, so Mir Noor-ud-din Mengal was named the Organizer of the Party. After successfully organizing the council session of PNP where Mir Hasil Bizenjo was named President, Mengal went back to being the Deputy Organizer of the Party while Raziq Bugti became the Organizer. A few months after this, in 1992, Mir Noor-ud-din was elected as the Vice President of PNP, an office he held until the merger of PNP with BNM in 1996. By 1996 it seemed that no single political party was able to represent the whole Province of Balochistan. In light of this discussions began between the leaders of Pakistan National Party and Baloch National Movement. Mengal played a central role in these talks and was pivotal in the merger of the two parties to form Balochistan National Party. Mir Noor-ud-din was elected as a member of the Central Executive Committee of BNP after the merger and held the position until his death in October 2010. Mengal remained an active and loyal member of the BNP right up until his death. When the Balochistan National Party was split into two factions, i.e., BNP Awami which was a forward block led by Israr Zehri, and BNP which was led by Akhtar Mengal, Mir Noor-ud-din remained in BNP proving his loyalty. He set up his political base in his hometown of Kalat and was arrested and persecuted for his political beliefs numerous times from 2000 to 2007 . In 2006, Balochistan National Party announced a Long March against, what they termed, the continued exploitation of the Baloch land and people by the Establishment especially during the dictatorship of General Pervez Musharaff.