"Euchambersia" was small and short-snouted for a therocephalian, with the type skull having a reconstructed length of approximately , accounting for crushing and deformation in the fossil. The second known skull belonged to a smaller individual, with a length of ; it was probably immature, judging by the lack of fusion in the skull. According to the initial description, the eye socket of "Euchambersia" was rather small. The branches of the postorbital and jugal that usually surround the back and bottom of the eye socket in therocephalians appear to be either very reduced or absent entirely. Meanwhile, the top of the eye socket is formed by the prefrontal, and the frontal is also small. The skull does not bear a pineal foramen. Like "Whaitsia", the pterygoid and palatine of the palate are not separated from the transpalatine, further to the side of the jaw, by any sort of opening. Although the skulls are incompletely preserved, CT scanning suggests that each premaxilla held five incisors, with the sockets becoming progressively larger from the first to the fifth incisor. Like other theriodonts, the crowns of the incisors are conical; they also lack serrations, unlike gorgonopsians and scylacosaurian therocephalians. The interior edge of the incisors seems to be slightly concave, and the back edge appears to have a ridge. The smaller specimen has a displaced incisor preserved within its nasal cavity; it is more strongly recurved and has wear marks on its top edge, suggesting that it is probably a lower incisor. Its fourth incisor also has a replacement tooth growing behind it, accompanied by resorption of the root. The type specimen preserves the right canine. Like other therocephalians, the canine of "Euchambersia" was very large, resulting in a specialized predatory lifestyle that incorporates a sabertooth bite into prey killing. It is round in cross-section, and bears a prominent ridge on the side of its front surface. Immediately beside this ridge is a shallow depression that becomes wider near the top of the tooth, which is probably the same structure as the groove interpreted by some authors. Theriodonts usually replace their teeth in an alternating (or distichial) pattern, such that the canine tooth is always functional; both skulls of "Euchambersia" show no sign of any replacement teeth developing, suggesting that "Euchambersia" was reliant on having both canines present and functional simultaneously.