On August 11, 2016, the Saguaros became the 2016 Pecos League Champions by defeating the Trinidad Triggers 2 games to 0 in a 5-4 victory. Entering the bottom of the 9th inning, the Trinidad Triggers were leading 4-1. Catcher Jesse Baker scored the winning run in the bottom of the 9th inning when Christian Schneider threw a wild pitch to pinch hitter Thomas McKenna. The Saguaros set a Pecos League record with 51 wins in a season. Kirby Campbell was announced as the new manager on October 12, 2016, while the previous manager, J.D. Droddy, remained on the Saguaros as the Director of Player Procurement until becoming the manager of the Salina Stockade (baseball) of the American Association of Independent Professional Baseball. Campbell, a 2014 graduate of the University of Arkansas at Pine Bluff, began the 2016 season as the starting first baseman of the Great Bend Boom and became Great Bend's manager midway through the season. Five players returned from the inaugural season: pitchers Brandon Cook, Jake Eaton, and Matt Kelley, as well as outfielders Burnell Dailey and Thomas McKenna. The Saguaros finished the season with the best record in the Pecos League, 46-11, but they lost in the playoffs to the High Desert Yardbirds 1-2 in the Pecos League Pacific Division Series. The Saguaros moved from the Pacific Division to the Southern Division of the Pecos League. The team also moved their home field to Gene C. Reid Park Field #5. Bill Moore, a resident of Mesa was announced as the new manager on December 16, 2017. He had originally considered taking the job in 2016. Ryan Retz, a Canyon del Oro High School graduate and Pecos League All-Star in 2016 for the Saguaros, returned after a one-year hiatus from the team. Left-Handed Pitcher Ryan Baca and Infielder Kevin Baron returned from the previous year. The Saguaros played a Spring Training game against the Ruidoso Osos at Reid Park Field #5 on Sunday, May 20, 2018. It was the first time the team had played a Spring Training game against another team. On July 4, 2018, the Saguaros moved to Cherry Field since it had lights so that home games could be played at night and start later at 7:00 P.M. The Saguaros moved back to the Pacific Division.