List of San Francisco 49ers starting quarterbacks  These quarterbacks have started at least one game for the San Francisco 49ers of the National Football League. They are listed in order of the date of each player's first start at quarterback for the 49ers. The number of games they started during the season is listed to the right in parentheses. "In the NFL era (since 1950 season)" These quarterbacks have the most starts for the 49ers in regular season games in the NFL era (since 1950 season). "In the NFL era (since 1950 season)"