In 1970, he presented his papers on radiocluster, examining the graphs and functional behaviour of the fission products with experimental and calculated potential energies. In 1970, Alam joined the Pakistan Atomic Energy Commission's Pakistan Institute of Nuclear Science and Technology (PINSTECH). He initially joined the Computer department but moved to Physics Division there. In 1974, Alam joined the Theoretical Physics Group under the directorship of his old mentor Abdus Salam (TPG). However, in 1975, Alam took the transferred at the Nuclear Physics Division to demonstrate research in high-speed rotationally fixed axis machine separation of the uranium isotope U-235 from other isotopes. In 1976, Alam was the director of a team compromising Anwar Ali, Dr. Fakhr Hashmi, Javed Arshad Mirza, Eqbal Ahmad Khokhar, assisted by the members of Corps of Electrical and Mechanical Engineering. In spring of 1976, Abdul Qadeer Khan joined the gas centrifuge programme as he replaced Alam. While researching in the United Kingdom, Alam had never seen a gas centrifuge, yet he was the director of the gas centrifuge programme but had only a rudimentary knowledge of them. Alam had only knowledge based on literature of the Manhattan Project and Jesse Beams work brought by Abdus Salam in 1972. Alam reviewed the blueprints of a gas centrifuge brought by Abdul Qadeer Khan and later identified as incorrect and incomplete. Not wanting to give up, Khan continued to work on the gas centrifuge, while Alam paid a visit to Quaid-e-Azam University to deliver a lecture on Mathematical physics. It was here, Alam met with Tasneem Shah, a mathematician, and delegated Shah to join the centrifuge programme. Together with Shah, Hashmi, Mirza, Khokhar, Ali, Alam formed the "Directorate of Industrial Liaison", a codename of the electromagnetic isotope separation project. Alam and his team established the approximation and reasonable percent error for the actual value for weapon-grade uranium. The electric vector equation problems, after applying Stokes' law, in the centrifuges were learned and mastered at Kahuta, and temperature difference in uranium hexafluoride (UF6) to flow from top to bottom; it was here a team of Alam and Khan had done tremendous amount of scientific research on complex and dynamic problems in uranium enrichment. According to the reference written in "Eating Grass", it was Alam, Fakhar Hashmi, Anwar Ali, and A.Q. Khan's research group that helped achieved the first enrichment into weapon-grade uranium, in a record timelime.