The ground echelon sailed on the SS "William T. Barry". The air echelon of the squadron was delayed in Tunisia and was not entirely lodged at the squadron's combat station of San Giovanni Airfield, Italy until 1 February 1944, and the squadron flew its first mission that month. The squadron was engaged primarily in the strategic bombing campaign against Germany, attacking targets like airfields, factories, oil refineries, harbors, marshalling yards in Italy, France, Germany, Austria, Hungary, Romania, and Yugoslavia. On 2 April 1944, the squadron attacked a ball bearing plant at Steyr, Austria for which it earned a Distinguished Unit Citation (DUC). The primary target, the Daimler-Pusch aircraft engine factory was obscured by clouds, so the unit attacked the nearby ball bearing plant although attacks by an estimated 75 twin engine fighters continued through the bomb run and heavy, accurate flak was encountered. The squadron lost two Liberators in the attack, but claimed the destruction of six enemy aircraft. Five crewmembers from one of the B-24s lost in the attack bailed out in territory controlled by Yugoslav Partisans and were able to evade German forces and returned to the squadron a month after the attack. On 26 June 1944, the squadron encountered fighter opposition that was described as the strongest Fifteenth Air Force had encountered to date, and which destroyed several Liberators of the 455th Group, which was leading the 304th Bombardment Wing on the raid. On this mission, the squadron suffered its heaviest losses of the war, with six planes lost to enemy action. Only one of the squadron's Liberators that reached the target returned safely. The squadron pressed its attack on an oil refinery at Moosbierbaum, Austria, for which it received a second DUC. The squadron provided air support to ground forces in Operation Shingle, the landings at Anzio and the Battle of Monte Cassino in the spring of 1944. It knocked out coastal defenses to clear the way for Operation Dragoon, the invasion of southern France in September. As Axis forces were withdrawing from the Balkan peninsula in the fall of 1944, the squadron bombed marshalling yards, troop concentrations and airfields to slow their retreat. It flew air interdiction missions to support Operation Grapeshot, the Spring 1945 offensive in Northern Italy. The squadron flew its last combat mission on 25 April 1945 against rail yards at Linz, Austria. Following the surrender of German forces in Italy, it flew some supply missions and transported personnel to ports and airfields for shipment back to the United States.