Early in her second term, Pillich cosponsored a bill that would provide tax credits to businesses that increase their payrolls and expand into vacant facilities. In November 2012, Pillich was elected to a third term, despite redistricting viewed as unfavorable to her chances. She garnered 51.68% of the vote, defeating Republican Mike Wilson (43.95%) and Libertarian Robert R. Ryan (4.37%). Pillich ran unsuccessfully for Treasurer of Ohio in 2014. She announced on March 13, 2017 that she will be a candidate for Governor of Ohio in 2018. On January 18, 2018, she announced that Marion mayor Scott Schertzer was her running mate. She dropped out of the race and endorsed Richard Cordray on February 13. On June 9, 2018, Pillich was elected as co-chair of the Hamilton County Democratic Party.