At the same time, it has set up basic research, the results of which have made it possible to establish relations between oxidative stress and immune functions. In 2003, he joined Inserm to set up the clinical research department at the Institute's head office under the direction of Christian Bréchot where he was able to develop the national network of clinical investigation centres and Biological Resource Centres (Biobanks), Inserm's clinical research promotion activities in conjunction with the Strategic Orientation and Monitoring of Clinical Trials Committee (Cossec), biotherapies in Inserm units, etc. In 2007, he participated in the setting up of thematic research and care networks (RTRS) from the Directorate General for Research and Innovation of the Ministry of Higher Education and Research. Since 2010, he has been an advisor to the Secrétaires Perpétuels of the French Academy of Sciences where he participated in the creation in October 2011 of the foundation for scientific cooperation: Fondation pour l'éducation à la science La main à la pâte, then chaired by Pierre Léna. He was the delegate of the president of the foundation Maison de Louis Pasteur. He developed the "Terre de Louis Pasteur" heritage interpretation centre project in conjunction with the Jura General Council and the communes of Dole and Arbois, which became a Public Establishment for Cultural Cooperation (EPCC) in January 2014. He is currently in charge of the partnership foresight of the French Academy of sciences, particularly in the framework of the programme for a scientific universalism initiated on his recommendations in June 2014. He has published to date more than 120 scientific articles and approximately 20 patents.