Example of sites predicted for O-GlcNAcylations, a mechanism in which a O-linked N-acetylglucosamine (O-GlcNAc) is added and important for regulation of cellular processes, are 488, 744, and 732. Examples of sites predicted for glycations, a mechanism in which glucose binds with proteins and lipids, are 140, 359, 669, and 776. Example of sites predicted for O-glycosylation, a mechanism in which sugars ormonosaccharides add to hydroxyl groups of proteins, occur on 179 and 386. There are several identified homologs of the zc3h11b protein in a variety of species including various mammals, insects, and amphibians. Currently, there is one paralog of ZC3H11B in the same CCCH-type zinc finger family based on BLAST analysis (NCBI). C12orf50 ("H. sapiens)" has also been predicted as a paralog of ZC3H11B. There are several species that have been found as having orthologs to the zc3h11b protein in their genome based on BLAST analysis (NCBI). ZC3H11A ("B. Taurus"), Zc3h11a ("M. musculus"), Zc3h11a ("R. norvegicus"), ZC3H11A ("G. gallus"), zc3h11a, ("X. tropicalis"), zc3h11a ("D. rerio"), AT2G02160 ("A. thaliana"), ZC3H11A ("M. domesticia"), zc3h11a ("A. carolinensis"), and ZC3H11A ("S. scrofa") have also been predicted as orthologs of ZC3H11B. Current research has identified ZC3H11B as single-nucleotide polymorphisms (SNPs) that are the most common genetic variation among groups with high myopia and corneal astigmatism. As of April 2020, there have been no other published association studies linking ZC3H11B with other conditions. Myopia, also known as shortsightedness or nearsightedness, is a condition caused by a refractive error in which the shape of the eye is either elongated or the cornea is too curved. In developed countries, this condition occurs in over 50% of the population with a high rate of occurrence among adults (80-90%) in East Asia and occurs approximately in 30% of the population in the United States.