On December 8, 2009, the Arroyo brothers issued a press release through their mother, Milagros Acevedo, informing that they were no longer interested in continuing their amateur careers. In the letter, they report differences with the criteria used to provide economical support to high-performance athletes, as well as schedule conflicts with their original plans to pursue a professional career after the 2010 Central American and Caribbean Games. These concerns were restated in a subsequent press conference, where they noted that supporting their respective families was the main reason to pursue a professional career. On January 12, 2010, PR Best Boxing announced the official signing of both brothers. Arroyo's debut was scheduled for February 27, 2010, where he competed in the bantamweight division as part of a card titled "Haciendo Historia", where Wilfredo Vázquez, Jr. fought Marvin Sonsona for the super bantamweight world championship. His opponent, Giovanni Rivera, had a previous experience of two professional fights. The fight began with Rivera moving around the ring, while Arroyo pursued him while engaging on the offensive, eventually scoring a knockdown. After 25 seconds of the second round had passed, he scored a second knockdown, prompting the referee to stop the contest by technical knockout. In his second fight, Arroyo defeated Steve Cannell by unanimous decision, winning all four rounds. Next he won a consecutive decision over Jairo Delgado. In his first six-round fight, Arroyo defeated Jason Rorie by technical knockout. On August 28, 2010, he scored a unanimous decision win over Sigfredo Medina. Arroyo then entered the first knockout streak of his career, which began with a first round victory over Israel Rojas. This run was completed by third and first-round technical knockouts over Eduardo Meléndez and Ivan Moxey. However, Arroyo was forced to rest eight months between these two fights after suffering a chin fracture, making his return in the super flyweight division. He then faced Shawn Nichol in consecutive fights, winning both by unanimous decision in six rounds. On September 27, 2012, Arroyo defeated former world champion José López by technical knockout in four rounds. He repeated this performance against Felipe Rivas, winning the World Boxing Organization's Latino championship. Arroyo returned with a unanimous decision wins over Jairo Hernández in eight rounds. He won the next fight in equal fashion, this time against former contender David Quijano.