Manchikanti has sponsored the Gandhi Medical College Alumni Education Center, located in Hyderabad, Telangana, India. In his honor, the auditorium was named the Manchikanti Laxmaiah Auditorium. Additional philanthropic support by the Manchikanti Trust includes establishing a Sri Venkateswara temple in Bodangparthy. In his honor, the McCracken County High School in Kentucky named the school's library "The Manchikanti Library". In his honor, the Murray State University Paducah Regional Campus in Kentucky named a classroom and laboratory the "Dr. Laxmaiah Manchikanti Classroom and Laboratory." Dr. Laxmaiah Manchikanti, MD provides a yearly scholarship at Murray State University, Kentucky. He has written and edited twelve books including the most recent, Essentials of Interventional Techniques in Managing Chronic Pain, published 4 Jan 2018. He has also written over 500 articles listed in the index medicus (PubMed) of the United States National Library of Medicine. In addition to articles based on his randomized trials and clinical research of interventional pain management techniques, he has provided analysis of public health policy. Additional topics he has written on include medical coding, compliance, practice management, and the deleterious effects of prescription opioids with their overuse, misuse, abuse, and diversion.