Head coach Bill Belichick named Mingo the fourth outside linebacker on the Patriots’ depth chart to start the regular season. He was listed behind Jamie Collins, Jonathan Freeny, and Shea McClellin. In Week 6, Mingo collected a season-high two solo tackles during a 35-17 victory against the Cincinnati Bengals. Mingo was limited to 11 combined tackles (nine solo) in his only season with the Patriots, but appeared in all 16 games with zero starts. The New England Patriots finished first in the AFC East with a 14–2 record and earned a first round bye. On January 14, 2017, Mingo appeared in his first career playoff game as the Patriots defeated the Houston Texans 34–16 in the AFC Divisional Round. The following week, they defeated the Pittsburgh Steelers 36–17 in the AFC Championship Game. On February 5, 2017, Mingo appeared in Super Bowl LI and recorded two solo tackles as the Patriots defeated the Atlanta Falcons 34–28. Mingo appeared exclusively on special teams during the game and recorded both his tackles while covering punt returns. On March 9, 2017, the Indianapolis Colts signed Mingo to a one-year, $2 million contract that includes a signing bonus of $500,000. Mingo reunited with teammate Jabaal Sheard for the third time. They were teammates on the New England Patriots and Cleveland Browns. Mingo competed against John Simon and Jabaal Sheard to be the starting strongside linebacker. Head coach Chuck Pagano named Mingo the backup strongside linebacker, behind John Simon, to begin the regular season. In Week 16, he collected a season-high eight solo tackles and made one sack during a 23-16 loss at the Baltimore Ravens. On December 31, 2017, the Indianapolis Colts fired head coach Chuck Pagano after finishing the season with a 4-12 record. Mingo finished his lone season with the Indianapolis Colts with 47 combined tackles (35 solo), two pass deflections, and two sacks in 16 games and six starts. On March 16, 2018, the Seattle Seahawks signed Mingo to a two-year, $6.80 million contract that includes $3.20 million guaranteed and a signing bonus of $2.20 million. Throughout training camp, Mingo competed against D. J. Alexander to be a starting outside linebacker. Head coach Pete Carroll named Mingo and K. J. Wright the starting outside linebackers to begin the regular season. They started alongside middle linebacker Bobby Wagner. In Week 6, Mingo collected a season-high seven solo tackles during a 27-3 victory at the Oakland Raiders.