Burhan Uray married twice. He had four sons with his first wife, and all were educated abroad and worked in his businesses. In September 1977, he married Betty Pai (), a Taiwanese television presenter. In 2013, Pai published Uray's biography in Chinese, which was published in English in 2016 under the title "Love in the Forest with Burhan Uray". According to the biography written by his wife, Uray was diagnosed with colon cancer in 1992 and had two operations in Singapore. In 2003, he received an operation in the United States for liver cancer. In 2007, he had a stroke while travelling in Japan. Uray died on 2 October 2018 in New York, aged 86. He was buried at Nirvana Memorial Park in Sibu, Malaysia on 7 October.