And Then There Was One (1994 film)  And Then There was One is a 1994 television film directed by David Jones and starring Amy Madigan and Dennis Boutsikaris. The film first aired on the Lifetime Television network on March 9, 1994. Roxy and Vinnie Ventola are a successful television screenwriting couple, who are struggling to conceive a child. Aside from that the couple have the perfect, happy marriage. After years of fertility treatments, the couple manage to conceive a daughter, Miranda, who falls ill with what is at first believed to be the flu, and then pneumonia. However, the underlying cause is soon revealed when the couple learn that their newborn has AIDS. Soon afterward, the two parents are also diagnosed with the virus. The film follows the family as they struggle to deal with the social, spiritual and physical tolls that the disease exacts on its sufferers. The film stars Amy Madigan as Roxy Ventola, Dennis Boutsikaris as Vinnie Ventola, and Jane Daly as Lorrie. Other cast members in the film include Jennifer Hetrick as Janet, Martha Henry as Dr. Moore, and Kenneth Welsh as David Burns. The film's production companies were Freyda Rothstein Productions and Hearst Entertainment Productions. Based on real events, the film follows the story of two Los Angeles-based screenwriters who had attended a fertility clinic in order to conceive a child, before HIV testing became routine. The couple's implant was successful, but the family discovered they had the AIDS virus. Vinnie Ventola died in 1991, and the baby Miranda died of the disease only a day later. Roxy Ventola was a co-producer of "And Then There was One" and she remarried in 1993, to AIDS activist Matthew McGrath, before dying from AIDS on November 14, 1994. She had become an activist herself and a successful advocate for peer counseling and peer support programs. She was president of the Board of Women at Risk, a support service for women with HIV/AIDS; a co-founding member of Women Alive, a peer group run by and for women volunteers with HIV/AIDS; a founding member of Friends for Life, a support service for heterosexuals with HIV/AIDS; and an active member of ACT UP/LA. Her play, "After the Bomb", which was about a post-AIDS world, was produced in the spring of 1994, at Open Fist Theater in Los Angeles. She performed in the Michael Kerns play, "AIDS, US Women: Silent NO More."