Produced by G. Dhananjayan, Thiru revealed that the film would be an action thriller where Karthik would portray a government official and Gautham would portray a boxer. Regina Cassandra and Varalaxmi Sarathkumar were signed to portray the lead female roles, while Sathish was cast in a further supporting role. Thiru also cast veteran directors, Mahendran and Agathiyan in pivotal acting roles, with the latter being the director's father-in-law. After a period of deliberate suspense, the team announced that the film would be titled "Mr. Chandramouli". The film's title is borrowed from a dialogue spoken by Karthik in "Mouna Ragam" (1986). Production began in late November 2017, and continued throughout early 2018. Regina Cassandra dubbed for the first time for her role in this film. The soundtrack album of "Mr. Chandramouli" consists of 6 songs composed by Sam CS and was released on Sony Music on 25 April 2018. The title track was co-sung by actor Sivakumar's daughter Brindha, who made her playback singing debut with this film. Chandramouli" released on 6 July 2018.