Charlotte Harbor, Florida  Charlotte Harbor is a census-designated place (CDP) in Charlotte County, Florida, United States. The name Charlotte Harbor also refers to Charlotte Harbor (estuary) and Charlotte Harbor Preserve State Park, a preserve with of shoreline along Charlotte Harbor in Charlotte County. The population of Charlotte Harbor was 3,710 at the 2010 census. It is part of the Punta Gorda Metropolitan Statistical Area. Charlotte Harbor is located at (26.963897, -82.062267) on the north bank of the Peace River, the main tidal inlet to the Charlotte Harbor estuary, itself an arm of the Gulf of Mexico. U.S. Route 41, the Tamiami Trail, crosses the Peace River between Charlotte Harbor and Punta Gorda via the Barron Collier Bridge (northbound) and the Gilchrist Bridge (southbound). According to the United States Census Bureau, the Charlotte Harbor CDP has a total area of , of which is land and , or 53.95%, is water. On August 13, 2004, Hurricane Charley first made mainland landfall at the mouth of Charlotte Harbor.