When Margo leaves her house to visit some friends, the tramp will create a trap to expel the mouse from her house. However, the vagabond's ambition will be excessive and that will cause him to fall into his own trap. Not everything will be bad experiences for Margo. In a sequence, Margo will visit her lovely Aunt Adelina to celebrate her birthday. During the journey, the little mouse will meet Jurand, a bitter beaver who will be very rude to her and her aunt. Margo and Adelina will teach him that he should be kinder to people, otherwise he will be left alone. In another moment, Margo and her friend Anna, a sparrow, will have to face an evil cat that he will want to eat them. One day, Margo invited her friend Anna to have tea at her house and then weave a tapestry with the melodies that Anna sang. Her pleasant song reaches the ears of the bad cat that he will want to eat the mouse and the sparrow. The cat will try to break the windows of Margo's house, also create holes to enter, but the intelligence and rapidity of the two friends will make their plans fail. However, when the cat decides to flood Margo's house with water, she decides to take out her gramophone and put a disc with barking dog sounds to scare the bad cat away. Among her other adventures will be to defeat a terrifying stork that wants to eat it or face the owl that lives in an old castle. Thanks to her intelligence and the strong friendship she has with other characters, Margo will learn to live and mature at every moment. Originally, TV series was broadcast sporadically between 1976 and 1983 on TVP Poland. After finishing TV animated series in 1983, Studio Filmów Rysunkowych decided to release "Margo the Mouse" in several countries. In 1985, the movie premiered in the former Soviet Union turned into a compilation movie with eight episodes of original TV animated-series. It's that compilation movie that premiered the same year in the former East Germany. Its good reception caused that it was re-released in Poland in 1987, as a compilation movie. The film, then, premiered in direct domestic format to video in several countries of the world such as France or Spain. In France it was premiered by Facets Video, while in Spain the license was held by Megavisión S.L.  Years later, in 2007, the film was part of the Ghibli Museum Library, the selection of television series, short films and international feature films that the prestigious Japanese animation studio, Studio Ghibli, distributes in Japan.