The United States entered the tournament ranked number one in the world. The United States qualified two competitors in the men's single event as a result of Bipartite Commission Invitation places. The players invited were Steve Baldwin and Jon Rydberg. The United States qualified four players in the women's single event. Emmy Kaiser and Dana Mathewson qualified via the standard qualification route. Kaitlyn Verfuerth qualified via a Bipartite Commission Invitation place. Russia had qualified two player in the women's singles event, Ludmila Bubnova and Viktoriia Lvova. Following their suspension, one spot was re-allocated by the IPC to the United States' Shelby Baron. The United States qualified three players in the quad singles event. Nicholas Taylor and David Wagner qualified via the standard route. Bryan Barten qualified via a Bipartite Commission Invitation place.