He was spotted by producer S. Thanu during his family function. In 1998, he joined the Film Institute in Chennai and obtained a diploma in acting after a one-year course. He made his debut in 2002 with the movie "Mounam Pesiyadhe" along with Suriya and Trisha Krishnan by film director Ameer. Director Ameer was looking for a cheerful and well built hero to play the co-role with Suriya. Nandhaa immediately fit the criteria and was therefore selected for the role. "Punnagai Poove" in 2003, showed him as a full-time hero. These films were hits. In 2005, he acted in "Selvam". In a freak mishap, he suffers an injury on his head and he forgets all about his past. Nandha playing a confused youth has given a good and matured performance. Donning a tricky character. In 2006, he appeared in two movies as "Kodambakkam" and "Aanivaer". He play in action film, "Agaram" (2007). The film was released to positive reviews. Followed by "Urchagam" (2007). His movie "Eeram" (2009) was a huge hit produced by acclaimed director S. Shankar. It was also released in Telegu titled "Vaishali", released by Dil Raju. Following the success of "Eeram", director Shankar again cast him in his production for the second time in "Anandhapurathu Veedu" (2010), directed by Naga. Then he starred alongside Jiiva in "Vanthaan Vendraan" (2011). He starred in "Vellore Maavattam" (2011), in which he played a cop. After two years without movies, Nandha became an action hero in movies as "Athithi" (2014), "Katham Katham" (2015), "Adhibar" (2015) and "Kallaattam" (2016). In 2018 again after "Mounam Pesiyadhe", he starred alongside Suriya in "Thaana Serndha Kootam" directed by Vignesh Shivan for studio green productions, which turned out to be a blockbuster in Tamil and in Telegu titled "Gang". He has also been starred in a web series produced by Ekta Kapoor for Balaji teleflims which was Tamil s first web series directed by Kaushik.