The program, which was funded in 2015 in response to the Ebola epidemic, equips healthcare facilities and trains frontline medical workers to confront outbreaks of infectious diseases. The funding enabled New York City and other health systems to run more drills, exercises, and collaborative public health protocols. Madad and Klain advocated for Congress to ensure the full network of healthcare institutions remains funded to protect against future outbreaks. Their warning came just months before COVID-19 reached the United States. As the COVID-19 pandemic was unfolding, Madad emphasized the need to monitor the situation and the available research around the pandemic's trajectory and effective approaches to mitigation. As COVID-19 made its way to New York City, Madad oversaw trainings and simulations to prepare healthcare workers for the coming demands that would be placed on the healthcare system. She accelerated training, ensuring protocols were incorporating the latest procedures recommended by the Centers for Disease Control and Prevention (CDC) and public health officials. She also instituted respiratory stations at the entrance of hospitals, which ask incoming patients if they have a fever, cough, or rash to take a mask and sanitize their hands immediately. From 2009 to the present, Madad has taught at the University of Maryland, College Park's Graduate Program for Biotechnology and Biodefense as an assistant professor. Madad is on the faculty of the United States Department of Health and Human Services's National Emerging Special Pathogen Training and Education Center's (NETEC) National Ebola Training and Education Center, funded by the Office of the Assistant Secretary for Preparedness and Response (ASPR) and the Centers for Disease Control and Prevention (CDC). On January 24, 2020, Netflix released the documentary series "", which followed Madad in her role at the Special Pathogens Program working to prevent an outbreak from occurring and prepare healthcare workers in the event that one does. The film portrays her working to secure funding to prepare personnel in the event of an outbreak. The series was filmed in 2019 and was based on the premise that the world is due for another deadly pandemic. Filming preceded the coronavirus disease 2019 (COVID-19), which did not reach Madad's jurisdiction in New York City until March 2020. Since the release of the series and the emergence of New York City as the worst hit locality of the COVID-19 pandemic, Madad has discussed the outbreak and pandemic preparedness on outlets, such as "CNN", Fox News, "Good Morning America", and MSNBC. She has also worked to combat misinformation, educating the public on appropriate safety measures and helping them understand what information is actually reliable.