Notably, it led one of the most successful demonstrations of clinical decision support to enhance vaccine prescribing rates. In 2015, Jain joined CareMore, an integrated health plan and delivery system in 10 states that is headquartered in the Los Angeles suburb Cerritos. CareMore was founded in 1993 and rose to national prominence for its model managing chronic disease and complex patients. Jain maintains a faculty appointment as an adjunct professor at Stanford University School of Medicine and continues to see patients at CareMore. Jain has authored more than 100 publications on health care delivery innovation and health care reform. His article, "Practicing Medicine in the Age of Facebook," in the "New England Journal of Medicine" explores the interface between social media and the practice of clinical medicine. He coined the term digital phenotype and described it in a paper in Nature Biotechnology with colleagues Brian Powers, Jared Hawkins, and John Brownstein. Two of his articles in "Journal of the American Medical Association", "Societal Perspectives on Physicians: Knights, Knaves, and Pawns?" (with Christine K. Cassel) and "Are Patients Knights, Knaves, and Pawn?" (with John Rother) build on the social theories of Julien LeGrand and apply them to physician and patient motivations. The book he co-edited with Susan Pories and Gordon Harper, "The Soul of a Doctor" has received mixed reviews. His article, "The Racist Patient," was mentioned in the New York Times and generated controversy about the obligation of physicians to patients with racist attitudes towards them and critical comments directed at Jain's perspective. Jain is the subject of a Harvard Business School case study written by dean Nitin Nohria. Jain was selected to Boston Business Journal's 40 under 40 list.