Cefsulodin  Cefsulodin is a third-generation cephalosporin antibiotic that is active against "Pseudomonas aeruginosa" and was discovered by Takeda Pharmaceutical Company in 1977. TAP Pharmaceuticals had a new drug application on file with FDA for cefsulodin under the brand name Cefonomil as of 1985. Cefsulodin is most commonly used in cefsulodin-irgasan-novobiocin agar to select for "Yersinia" microorganisms. This agar is most often used in water and beverage testing. The following represents MIC susceptibility data for various "P. aeruginosa" strains: