I-No  Video game reviewers have commented on her sex appeal, with some of them also remarking her winning pose as well as her clothes and electric guitar. Her fighting abilities and the difficulty to defeat her as a boss have also been noted by critics. I-No was first introduced in the third installment of the series, "Guilty Gear X2" (2002), where she appears as the primary antagonist and final boss. She carries with her an electric guitar nicknamed  that she uses to fight both using it as a bludgeon and playing it to create deadly sonic waves, and she also fights with her hat that can shoot projectiles out of a secret hole. I-No is one of That Man's servants, and she appears in every character's storyline, manipulating them against each other—for example, she gives fake bounty lists with the name of the people her master wants to kill, consisting entirely of other cast members, to Jam Kuradoberi and Bridget. As she works for personal gain instead of being only a puppet, in "Guilty Gear XX Accent Core Plus" (2008), she arouses insecurity in That Man who uses Anji Mito to capture her, eventually succeeding. She has three possible endings: she is captured by That Man and Raven to be punished, and she argues she only wanted to remove those who stood in her boss' way, but her master says that they're beneficial to what he has in mind for the world; she fights and defeats Dizzy and May, either subsequently becoming overwhelmed by Dizzy's power, and kidnapping May; or she is defeated by Baiken, being stabbed repeatedly, thus leading to her death. I-No is a playable character in "Guilty Gear Xrd" (2014), where she worked for That Man and became associated with Axl Low. I-No is also a playable character in the spin-off games "Guilty Gear Isuka" (2003), "Dust Strikers" (2006), and "Judgment" (2006). In a 2013 poll conducted by Arc System Works, I-No was voted as the 20th most popular character from the series. IGN named I-No their "first-favorite new character design" from "Guilty Gear X2". GameDaily ranked I-No thirteenth on their "Top 25 Most Bizarre Fighting Characters", repeating the sentiment in a later article series called "Babe of Week", featuring her in "Asian Beauties" and "Guilty Gear Babes". "Complex" placed the boss battle with I-No in "Guilty Gear X2 #Reload" as the fourteenth coolest boss battle of all time, saying she is not a hard boss "but the fact that she fights with a blue guitar is pretty amazing", and along with her stage, the hell above the clouds, "you have one epic boss battle."