The Owls would answer with a touchdown run early in the second in taking a 21–3 lead only to see the blazers respond with a pair of Joe Webb touchdown passes, 20-yards to Zach Lankford and 19-yards to Frantell Forrest, in closing the gap to 21–17. However, FAU would score once more before the half in taking a 28–17 halftime lead. The Blazers would open the third by scoring on a 2-yard Aaron Johns run only to see the Owls once again respond with another touchdown. After a late 43-yard Waters field goal in the third, UAB's final points would come in the fourth on a 10-yard Justin Brooks touchdown run. Traveling to Knoxville to face the Volunteers, all the Blazers could manage was a single 47-yard Swayze Waters field goal in the third to avoid the shutout in this 35–3 defeat. For the game, UAB was outgained on offense 275 to 548 total yards. The Blazers would amass 486 yards of total offense in winning their first game of the 2008 season with a 44–10 victory over the Hornets of Alabama State. UAB would strike first on a 41-yard Joe Web run with the Hornets responding in kind on a 39-yard Rei Herchenbach touchdown pass to Darius Mathis in tying the game at 7–7 midway through the first quarter. The Blazers would regain the lead late in the first quarter, and never relinquish it again on a 24-yard Webb touchdown pass to Jeffery Anderson. In the second, the Blazers would add another pair of touchdowns on an 11-yard Rashaud Slaughter run and a 36-yard Webb pass to Anderson in taking a 28–7 halftime lead. UAB would continue to amass points in the third on another pair of touchdowns coming on a 6-yard Slaughter run and 15-yard Justin Brooks run in extending their lead to 42–7 entering the fourth. In the fourth, each team would exchange a pair of field goals in bringing the final score to 45–10. For the game, Joe Webb would rush for 121 yards and a touchdown and pass for 238 yards and a pair of touchdowns. Traveling to face their second SEC opponent on the 2008 season, the Blazers were defeated 26–13 by the home Gamecocks in Columbia. After only connecting on a pair of Swayze Waters field goals in the first half, the Blazers lone touchdown came late in the fourth on a 1-yard Joe Webb run.