However, drug studies have confirmed that the powerful hallucinogenic effects of this drug can produce profound adverse reactions, such as acute panic reactions, psychotic crises, and "flashbacks", especially in users ill-equipped to deal with such trauma. The governors of Nevada and California both signed bills into law on May 30, 1966, to control LSD, making them the first two states to outlaw the manufacture, sale, and possession of the drug. The law went into effect immediately in Nevada, and on October 6, 1966, in California. Other U.S. states and the rest of the world followed with the ban. Renowned British intellectual Aldous Huxley was one of the most important figures in the early history of LSD. He was a figure of high repute in the world of letters and had become internationally famous through his novels "Crome Yellow", "Antic Hay" and his dystopian novel "Brave New World". His experiments with psychedelic drugs (initially mescaline) and his descriptions of them in his writings did much to spread awareness of psychedelic drugs to the general public and arguably helped to glamorize their recreational use, although Huxley himself treated them very seriously. Huxley was introduced to psychedelic drugs in 1953 by a friend, psychiatrist Humphry Osmond. Osmond had become interested in hallucinogens and their relationship to mental illness in the 1940s. During the 1950s, he completed extensive studies of a number of drugs, including mescaline and LSD. As noted above, Osmond had some remarkable success in treating alcoholics with LSD. In May 1953 Osmond gave Huxley his first dose of mescaline at the Huxley home. In 1954 Huxley recorded his experiences in the landmark book "The Doors of Perception"; the title was drawn from a quotation by British artist and poet William Blake. Huxley tried LSD for the first time in 1955, obtained from "Captain" Al Hubbard. Alfred Matthew Hubbard is reputed to have introduced more than 6,000 people to LSD, including scientists, politicians, intelligence officials, diplomats, and church figures. He became known as the original "Captain Trips", travelling about with a leather case containing pharmaceutically pure LSD, mescaline, and psilocybin. He became a 'freelance' apostle for LSD in the early 1950s after supposedly receiving an angelic vision telling him that something important to the future of mankind would soon be coming. When he read about LSD the next year, he immediately sought and acquired LSD, which he tried for himself in 1951.