In 1884, Patton married Ruth Wilson, daughter of Benjamin Davis Wilson, a prominent landowner, businessman, and politician, and Margaret (Hereford) Wilson. They had two children, Gen. George Smith Patton (1885-1945) and Anne Wilson "Nita" Patton (1887-1971). On June 10, 1927, Patton died at his Lake Vineyard home in San Marino. He was buried at San Gabriel Cemetery in San Gabriel, California.