Swiss Music Pedagogic Association  The Swiss Music Pedagogic Association (SMPA) (in German "Schweizerischer Musikpädagogischer Verband (SMPV)", in French "Société Suisse de Pédagogie Musicale (SSPM)", in Italian "Società Svizzera di Pedagogia Musicale (SSPM)", in Romansh "Societad Svizra da Pedagogia Musicala (SSPM)") is the umbrella organisation of music educators, pedagogues and music teachers in Switzerland. The SMPA has been founded in 1893 and nowadays has about 5000 members. It is divided in 21 sections (capital seat in Bern); acting chairman is Jakob Stämpfli. Proline—tRNA ligase  In enzymology, a proline—tRNA ligase () is an enzyme that catalyzes the chemical reaction  The 3 substrates of this enzyme are ATP, L-proline, and tRNA(Pro), whereas its 3 products are AMP, diphosphate, and L-prolyl-tRNA(Pro). This enzyme participates in arginine and proline metabolism and aminoacyl-trna biosynthesis. This enzyme belongs to the family of ligases, to be specific those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. The systematic name of this enzyme class is L-proline:tRNAPro ligase (AMP-forming). Other names in common use include prolyl-tRNA synthetase, prolyl-transferRNA synthetase, prolyl-transfer ribonucleate synthetase, proline translase, prolyl-transfer ribonucleic acid synthetase, prolyl-s-RNA synthetase, and prolinyl-tRNA ligase. Nerisopam  Nerisopam (GYKI-52322, EGIS-6775) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam. It has potent anxiolytic and neuroleptic effects in animal studies. Happy-Go-Lucky (2008 film)  Happy-Go-Lucky is a 2008 British comedy-drama film written and directed by Mike Leigh. The screenplay focuses on a cheerful and optimistic primary school teacher and her relationships with those around her. The film was well received by critics and resulted in a number of awards for Mike Leigh's direction and screenplay and lead actress Sally Hawkins's performance.