The following cabinet formation of 1948 resulted in a coalition agreement between the Catholic People's Party and the Labour Party (PvdA) which formed the Cabinet Beel I with Beel becoming Prime Minister of the Netherlands and remaining Minister of the Interior, taking office on 3 July 1946. Beel served as acting Minister of Colonial Affairs from 30 August 1947 until 3 November 1947 during a medical leave of absence Jan Jonkman. On 15 September 1947 Beel resigned as Minister of the Interior following reestablishment of the Ministry of General Affairs the cabinet department for the Prime Minister, taking office on 13 October 1947. After the election of 1948 Beel returned as a Member of the House of Representatives, taking office on 27 July 1948. Following the cabinet formation of 1948 Beel not giving a cabinet post in the new cabinet, the Cabinet Beel I was replaced by the Cabinet Drees–Van Schaik on 7 August 1948 and he continued to serve in the House of Representatives as a frontbencher. In September 1948 Beel was nominated as the High Commissioner of the Dutch East Indies, he resigned as a Member of the House of Representatives on 7 September 1948 and was installed as High Commissioner, serving from 29 October 1948 until 18 May 1949. Beel worked as a distinguished professor of Administrative law and Public administration at the Radboud University Nijmegen serving from October 1949 until December 1951 and as a distinguished professor of Administrative law and Public administration at the Catholic Economic University serving from March 1950 until December 1951. Beel was appointed again as Minister of the Interior in the Cabinet Drees I following the death of Johan van Maarseveen, taking office on 6 December 1951. After the election of 1952 Beel continued as Minister of the Interior and also becoming Deputy Prime Minister in the Cabinet Drees II, taking office on 2 September 1952. Beel served as acting Minister of Social Work from 2 September 1952 until 9 September 1952 before the appointment of Frans-Jozef van Thiel and served as acting Minister of Justice from 4 February 1956 until 15 February 1956 following the death of Leendert Antonie Donker. On 7 July 1956 Beel resigned after he was appointed as Chairman of the , a special commission that was tasked with the investigation into the influence of Greet Hofmans a friend and informal adviser to Queen Juliana. Beel was granted the honorary title of Minister of State on 21 November 1956. In February 1958 Beel was nominated as a Member of the Council of State, taking office on 1 April 1958. On 11 December 1958 the Cabinet Drees III fell and continued to serve in a demissionary capacity with Beel appointed as Formateur to form a new cabinet.