On November 2, 2010, Runyan defeated Adler 50%–47%. He is the fourth former NFL player to be elected to Congress, after Jack Kemp, Steve Largent, and Heath Shuler. Runyan was re-elected, defeating attorney Shelley Adler, the widow of John Adler (who intended to run in a rematch, but died suddenly in April 2011). Shelley Adler had defeated Jason Sansone for the Democratic nomination. Runyan won 54% of the vote, to Adler's 45%. Runyan announced that he would not seek re-election, after expressing frustration with his fellow Republicans over the government shutdown. Over the course of his tenure, Runyan had sponsored 15 pieces of legislation. Like most New Jersey Republicans, he was considered moderate relative to the national party. He voted with the Republican party 92% of the time. Key votes he supported included the payroll tax cut, the Balanced budget amendment, defunding of National Public Radio, and the Republican budget plan. In June 2013, Runyan was one of the sponsors to pass an amendment to H.R. 2217, the Department of Homeland Security Appropriations Act of 2014, which increased the Staffing for Adequate Fire and Emergency Response (SAFER) Grants, and the Assistance to Firefighter Grants (FIRE) by $2.5 million each. On November 6, 2013, Runyan announced he would not seek reelection in 2014. The following is a partial list of bills specifically sponsored (introduced) by Rep. Runyan. Runyan has three children with his wife, Loretta; they reside in Moorestown, New Jersey. His son, Jon Runyan Jr., played offensive line for the Michigan Wolverines football program and was drafted by the Green Bay Packers in 2020. Runyan appeared as a construction worker alongside other Philadelphia Eagles in the Season 4 episode "America's Next Top Paddy's Billboard Model Contest" of "It's Always Sunny in Philadelphia". In his spare time, Runyan works as an Uber driver in the Philadelphia area.