In 1711, it was redesignated line infantry and took part in the Quebec Expedition. In what remains one of the worst naval disasters in British history, the fleet ran aground in thick fog and over 890 men lost, including 200 members of the regiment. With the accession of George I in 1714, it was retitled The Kings Own and spent the next 30 years in Scotland and England. Sent to Flanders in 1744 during the War of the Austrian Succession, it garrisoned Ghent and when the 1745 Jacobite Rising broke out in August, it was transferred to Scotland and fought at the Battle of Falkirk Muir in January 1746. At the Battle of Culloden in April, it was based in the front line and took the brunt of the Jacobite charge; it suffered the heaviest casualties on the government side, with 18 dead and 108 wounded. Following the army reforms of 1751, the regiment was retitled 4th (King's Own) Regiment of Foot. At the start of the Seven Years' War in 1756, it was part of the Menorca garrison; forced to surrender in June it was transported to Gibraltar. It spent the rest of the war in the West Indies, taking part in the capture of Guadeloupe, Martinique and Saint Lucia before returning home in July 1764. When the American Revolutionary War began in 1774, it was sent to North America; over the next three years, it took part in numerous actions, including Lexington and Concord, Bunker Hill, Long Island and the Battle of White Marsh in December 1777. In early 1778, it returned to Saint Lucia where it was part of the garrison during the December 1778 naval battle of St. Lucia, part of the Anglo-French War. The regiment was sent to Nova Scotia in May 1787 and took part in the capture of Saint Pierre and Miquelon in May 1793. After returning to England, it embarked for the Netherlands in September 1799 and fought at the Battle of Alkmaar in October 1799 during the Anglo-Russian invasion of Holland. The regiment was sent to Portugal in August 1808 for service in the Napoleonic Wars and fought under General Sir John Moore at the Battle of Corunna in January 1809, before being evacuated to England later that month. It returned to the Peninsula in October 1810 where it fought at the Siege of Badajoz in March 1812, the Battle of Salamanca in July 1812 and the Battle of Vitoria in June 1813 as well as the Siege of San Sebastián in September 1813.