Later in the year he showed his versatility when presented "Coinne Le", a live Saturday night chat show, while also fronting the stations live coverage of the Galway Races. He hosted TG4's coverage of the Galway Races again in 2005. In 2006 Ó Sé began three seasons as host of "Glór Tíre", a country music talent show and in 2007 he presented "Dáithí ar Route 66" a travel programme about his journey on the famous U.S. highway. He was a contestant on "Charity You're a Star" in 2006. In 2007, he appeared on "Celebrities Go Wild", an RTÉ reality television show in which eight celebrities had to fend for themselves in the wilds of rural Connemara. He was a guest presenter on "The Panel" in 2008. He was one of the judges on RTÉ programme "The All Ireland Talent Show". He represented competitors from the West of Ireland and won the first series in 2009 with The Mulkerrin Brothers, a trad group from the Aran Islands. On 17 May 2010, it was announced that he would host the Rose of Tralee contest for 2010. He became the 11th host of the contest and the first Kerryman to compère. He was afforded a homecoming fit for a Sam Maguire Cup winner. He succeeded radio broadcaster Ray D'Arcy, who presented the competition on RTÉ television for five years from 2004 to 2009. On 28 August 2010, he started a new RTÉ 2fm radio show on Saturday mornings from 10am until midday. He co-presented "The Daily Show" with Claire Byrne on RTÉ One until the programme was axed in 2012. Since November 2012, he has been one of the presenters of RTÉ's daytime show Today on RTÉ 1. Since January 2014, Ó'Sé has also hosted various shows on TG4 on a part-time basis such as Fuaimrian Mo Shaoil, Gradaim Ceoil until they were both axed  In September 2018, it was announced that Ó'Sé would host a new chat show on TG4 every Thursday Night called Seal Le Dáithí. On 12 July 2012, Ó Sé married the 2008 New Jersey Rose, Rita Talty. On 17 March 2014 his wife gave birth to a boy, Mícheál Óg.