Kalbe Farma  PT Kalbe Farma Tbk is a pharmaceutical, healthcare and nutrition company in North Jakarta, established in 1966. The Company has expanded by strategic acquisitions of pharmaceutical companies, becoming an integrated consumer health and nutrition enterprise. The Kalbe Group has brands in the prescription drugs, OTC drugs, energy drink and nutrition products, distribution arm that reaches over 1 million outlets. Notably, the company produces misoprostol (sold under the brand name of Invitec), a drug which is used to treat stomach ulcers but is also widely used in Indonesia as an illegal abortifacient (abortion-inducing substance). Company brands in healthcare and pharmaceutical segments include Promag, Mixagrip, Woods, Komix, Prenagen and Extra Joss. Kalbe is the largest publicly listed pharmaceutical company in Southeast Asia with around US$5 billion in market capitalization and revenues of over Rp 15 trillion. Kalbe Farma was founded on September 10, 1966 by 6 siblings, Khouw Lip Tjoen, Khouw Lip Hiang, Khouw Lip Swan, Khouw Lip Boen (Also Known As: Dr. Boen, Boenjamin Setiawan), Maria Karmila, and F. Bing Aryanto. Kalbe Farma first began operations in a house garage that was owned by the founders.