The road enters Leicestershire and the district of Harborough as Harborough Road at the start of the five-mile (8 km) Market Harborough Bypass. It briefly re-enters Northamptonshire where there is a roundabout with the A427 (for Stoke Albany) and A4304 (former A427), and an exit for Great Bowden. The road is crossed by the Leicestershire Round. There is a turn for Foxton and Foxton Locks. It is crossed by the Midland Main Line. The A6 passes through Kibworth. The road becomes Leicester Road. It crosses the River Sence and there is a roundabout. The bypass ends with a roundabout, just before the road enters the district of Oadby and Wigston. On the outskirts of Leicester the road becomes London Road. There is a roundabout with Florence Wragg Way, where the road becomes Glen Road It then becomes Leicester Road before reaching the outer ring-road (A563), next to Leicester Racecourse. It becomes London Road, where the dual-carriageway ends, and it enters the city of Leicester, passing Leicester High School for Girls. There is a crossroads, for Stoughton Road (A6030) at Stoneygate, and a roundabout with the Victoria Park Road (B568). It passes close to Leicester University and many take-away shops. It crosses the Midland Main Line near Leicester railway station. In the centre of Leicester, it is subsumed into Leicester's inner ring-road, the A594. The A6 crosses the Grand Union Canal and the River Soar as St Margarets Way. It becomes dual-carriageway on the northern outskirts of Leicester and passes the National Space Centre in Belgrave as Abbey Lane. Later, it meets a roundabout with the A563 outer ring-road entering the borough of Charnwood. North of Leicester, as Loughborough Road, it meets the A46 Leicester Western Bypass just south of Rothley and the start of the four-mile (6.4 km) dual-carriageway Quorn-Mountsorrel Bypass. The road at this point follows the Soar Valley, and is mostly on embankment or viaduct, crossing the river four times. From here the road passes through Loughborough. North of Hathern is a dual-carriageway section which skirts the Leicestershire–Nottinghamshire border (the River Soar).