On 26 June 2012, Pope Benedict XVI appointed him the Archivist and Librarian of the Holy Roman Church. In March 2014 he announced that the Vatican Library was digitizing approximately 3000 handwritten manuscripts and considering extending the project to cover all its holdings. Bruguès served as President of the Organizing Committee of the Vatican Foundation Joseph Ratzinger - Benedict XVI for the Symposium on "The Gospels: History and Christology - Research of Joseph Cardinal Ratzinger, Pope Benedict XVI", which was held at the Pontifical Lateran University on 24–26 October  2013.