Curiously, his marriage certificate gives his name as "de' Fiori". From 1651 to 1667, they had six children. In 1657, he was finally accepted as a member of the Accademia di San Luca. After 1658, he did decorative work for Cardinal Flavio Chigi; painitng flowers on mirrors and basanite columns. He also collaborated with other artists to paint flowers with figures at the Palazzo Chigi in Ariccia. These paintings represent the Four Seasons and each artist was assigned to assist with one of them: Filippo Lauri (Spring), Carlo Maratti (Summer), Giacinto Brandi (Fall) and Bernardino Mei (Winter). They painted the figures and Nuzzi provided the flowers. Such projects made him increasingly famous and wealthy. He died in 1673, at the age of seventy, and was interred at the Basilica of San Lorenzo in Lucina.