She has been instrumental in taking up the issue of advertisements that depict actions which might prove fatal if copied by children, and also issues of indecent representation of women in the media. She is also part of the struggle of tribal residents in Uttarakhand fighting for their traditional rights against the conservation policies of the state government. She is a Rajasthani folk singer and has albums to her credit. She has been to 16 countries in the world as a cultural representative for the Rajasthani Ghoomar group. Along with the group, she conducts workshops to promote Rajasthani songs, dance and culture. Pratiba Naitthani has been the only non-Rajasthani singer who had the honour of singing and recording the state song of the Udaipur royal family- "Mharo veer Shiromani Des". In 2000, Pratiba Naitthani was among the first 7 women who participated in the Nanda Devi Raj Jat, a pilgrimage of Nandadevi Parvati in Uttarakhand. It is held once every 13 to 16 years. Previously, women were generally not allowed to participate in this pilgrimage which is 280 km long, going up to the altitude of 17.500 feet above sea level to be completed on foot in 22 days. She was among the 29 women selected by India Today in 2005 as Power Goddesses of India. Besides many awards for her contribution in the field of social service and media issues, she has been awarded the prestigious Pannadhai Award by Maharana Mewar Foundation, Udaipur for going beyond the call of duty for social service. She has also been honoured by the Mayor of Mumbai on International Women’s Day in 2007 as the "Outstanding Woman of Mumbai city".