The next week, Kuechly recorded 7 tackles, 2 passes defenses, and 2 interceptions for 49 yards and a touchdown against the Dallas Cowboys in a 33-14 win, which helped Carolina reach 11-0. During the game, Kuechly became the first player with picks on back-to-back plays from scrimmage since 1997 and upped his career total to 10, most among all linebackers since 2012. Additionally, his pick 6 was the first of his NFL career and the first one since his junior season at Boston College. He was awarded the All-Iron Award and NFC Defensive Player of the Week for his performance during the game; it was his fourth such honor in his career, setting a new Panthers' franchise record. According to PFF through the first 12 weeks of the season, Kuechly's 17.6 run-stop percentage ranked first for any defensive player regardless of position with at least 100 snaps against the run. Further, Kuechly was one of seven linebackers with 30 or more tackles in the run game, and just one missed tackle. In coverage, Kuechly had three interceptions and four passes defended with no touchdowns allowed. He also allowed the second-lowest passer rating among all linebackers when targeted in coverage at 47.4 and is the one of just three linebacker with more than 25 tackles in coverage, and only one missed tackle. During the Panthers week 14 victory over the Atlanta Falcons, Kuechly recorded his fourth interception of this season against quarterback Matt Ryan. His 11 career interceptions are the most by any linebacker since he came into the league in 2012. During the Panthers thrilling 38-35 victory over the New York Giants to move them to 14-0, Kuechly recorded 15 tackles, his highest total since 2014 Week 5. Kuechly was the winner of PFF's inaugural Dick "Night Train" Lane Award, given to the defender who performed the best in pass-coverage over the course of the season. Kuechly led all linebackers in allowing a passer rating of just 48.7 into his coverage (playoffs included). In the Panthers' 31–24 win over the Seattle Seahawks in the NFC , Kuechly intercepted Seattle quarterback Russell Wilson early in the first quarter and returned the pick 14 yards for a touchdown to give the Panthers a 14–0 lead. He added another "pick six" late in the Panthers' 49–15 win over the Arizona Cardinals in the . On February 7, 2016, Kuechly was part of the Panthers team that played in Super Bowl 50.