Nerinx hosts a variety of extracurricular activities. Students are strongly encouraged to join clubs, teams, and participate in fine arts to enrich their interests and interact with peers and classmates. The 30 clubs focus on a variety of topics from academics to service to leadership. Nerinx, more commonly known in the athletic world as home of the Markers, offers thirteen sports for the young women to participate in: swimming, soccer, track & field, lacrosse, diving, softball, field hockey, volleyball, tennis, golf, cross country, basketball and racquetball. In the 2010-2011 school year the girls had many athletic achievements. The golf team received 7th place in state, the cross country team took 2nd at sectionals, the tennis doubles team qualified for state, cross country brought home 5th place at state, and the JV racquetball team won 1st place in the state tournament. In 2015 the cross country team took first in state. The Heagney Theater was completed in the summer of 2007 and is the largest expansion project the school has seen since 1954. This addition to the school has four classrooms, a new music room, and a new theater. The theater seats 371 people and has an orchestra pit, scene shop and dressing rooms. The addition also holds two art labs and the fine arts department office.