As more boys began to attend Science, the Clinton contingent was gradually returned to its own main building. During their joint occupation, which lasted for 2 years until 1940, the two schools had separate teaching staff and classes, but the same supervision and administration. In 1946, as a result of the efforts of Meister, the faculty, and the Parents Association, the school became co-ed, giving girls of New York equal opportunity to pursue a quality education in a specialized high school, previously denied to them. This expansion to co-education preceded its rivals Stuyvesant (1969) and Brooklyn Tech (1972) by more than two decades. In 1958, after 20 years as principal of the school, Morris Meister resigned to become the first president of the newly organized Bronx Community College. Meister personally selected a teacher, Alexander Taffel, to succeed him as principal. From the beginning, the Parents Association and Principal Morris Meister campaigned for a new building. After twenty years, but under Principal Taffel, plans were finally completed for a new $8 million building, designed by the architectural firm of Emery Roth and Sons. The new building was on 205th Street near Bedford Park Boulevard, in a predominantly institutional area, between DeWitt Clinton High School and its large football field on one side, and Harris Field and Hunter College (now Lehman College) on the other. On March 3, 1959, students and faculty occupied the new building for the first time, solving the problem of how to move the books from the old library to the new in typical Bronx Science manner: on Friday afternoon each student took home five library books from the old building, and on Monday returned them to the new one. They entered a school equipped with more modern classrooms, laboratories, and technical studio areas. The main lobby entrance featured a , Venetian glass mosaic mural overhead, depicting major figures from the history of science such as Marie Curie and Charles Darwin under the protective hands of a God-like figure representing knowledge, with this quote from John Dewey: "Every great advance in science has issued from a new audacity of imagination." The mural is an original work by Frank J. Reilly entitled "Humanities Protecting Biology, Physics, Chemistry". Legions of students over the years, bemoaning the lack of swimming facilities, have sarcastically referred to the mural as "the Science swimming pool", perpetuating the idea – perhaps apocryphal – that a choice was made to fund a mural rather than a pool in the new building.