Overall, he finished the 2017 season with a career-low 659 rushing yards, six rushing touchdowns, 39 receptions, 266 receiving yards, and one receiving touchdown. On March 8, 2018, Murray was released by the Titans. On July 13, 2018, Murray announced his retirement from the NFL. In August 2018, one month after his retirement, Murray was added as a college football commentator for Fox Sports. On January 2, 2019, Murray joined Kevin Sumlin's staff at the Arizona Wildcats football team as the running backs coach. On January 27, 2020, Murray returned to his alma mater, the University of Oklahoma, as running backs coach. On June 20, 2013, actress Heidi Mueller gave birth to Murray's first child, a daughter, Savanna June. The couple announced their engagement on January 19, 2015. Murray and Heidi also have a son, Parker Ray. Murray started the DeMarco Murray Foundation with the mission to provide families with seriously and chronically ill kids with daily encouragement and life-changing experiences.