Eleven days after his maiden win Anthony Van Dyck was stepped up in class and started 8/11 favourite for the Group 3 Tyros Stakes at Leopardstown Racecourse. Partnered by Ryan Moore he raced in second place before taking the lead approaching the final furlong and recorded another easy win, coming home four and three quarter lengths clear of the Jim Bolger-trained Bold Approach. After the race Aidan O'Brien said "We always thought he would get a mile well, as he did in Killarney, but when you see him doing that over seven, you know he's a smart colt". Ryan Moore was again in the saddle when Anthony Van Dyck moved up to Group 2 class for the Futurity Stakes over seven furlongs at the Curragh on 26 August and started 4/6 favourite against five opponents. After tracking the leaders he went to the front inside the furlong and kept on well to win by half a length from his stablemate Christmas. O'Brien commented "I'm delighted... We always viewed him as a horse that would get middle distances next season. He had a tough enough race as they went all the way". In September the colt contested the Group 1 National Stakes at the Curragh and finished second of the seven runners, beaten one and a quarter lengths by the Godolphin colt Quorto. He was then sent to England for the Dewhurst Stakes at Newmarket Racecourse. He took the lead approaching the last quarter mile but was outpaced in the closing stages and came home third behind Too Darn Hot and Advertise. For his final run of the season, the colt was sent to the United States to contest the Breeders' Cup Juvenile Turf at Churchill Downs and was made the 3/1 joint favourite, but never looked likely to win and came home ninth behind Line of Duty. On 11 May 2019 Anthony Van Dyck made his seasonal debut in the Derby Trial Stakes over one and a half miles at Lingfield Park and started the 2/1 favourite against nine British-trained opponents. Ridden by Moore he settled in mid-division before taking the lead a furlong out and won by two and a quarter lengths from Pablo Escobarr. After the race the Ballydoyle representative Paul Smith said "[we are] delighted with him. There were a few fit ones in there that had run recently and we hadn’t run since last year. No doubt he’ll come on nicely for the run".