Due to his seeding, he received a bye into the second round, where he defeated Adrian Mannarino. He then went on to play Sergiy Stakhovsky, whom he defeated in straight sets. In the quarterfinals, Ferrer lost to Novak Djokovic. It was his first defeat in their four meetings on clay. Ferrer then pulled out of Rome, due to injury, but then traveled to Paris to play in the French Open. At the French Open, Ferrer was seeded seventh. He advanced with easy wins over Jarkko Nieminen, Julien Benneteau, and Sergiy Stakhovsky, before ultimately falling to ninth seed Gaël Monfils in five sets. Due to his round of 16 appearance, Ferrer moved up to no. 6 in the world. Ferrer then took a month off before traveling to London to play in the 2011 Wimbledon Championships, as the seventh seed. In the first round, he defeated Benoît Paire, and then defeated Ryan Harrison in five sets. He then defeated Karol Beck in straight sets to advance to the round of 16. However, he fell to eventual semifinalist Jo Wilfried Tsonga. After competing in two consecutive majors, Ferrer traveled to Sweden to play in the 2011 Swedish Open as the second seed. He reached the semifinals, where he defeated Nicolás Almagro, but lost to Robin Söderling. Ferrer was then set to begin his summer hard-court series in Toronto, but pulled out with a hairline fracture of his left wrist. He healed in time to play in the 2011 Western & Southern Open as the fifth seed. He won his second-round match against Grigor Dimitrov, before falling to Gilles Simon. Due to the result, Ferrer entered the top 5 in the ATP rankings again, becoming world no. 5. At the US Open, he lost in the fourth round to Andy Roddick in four sets. At the 2011 Shanghai Rolex Masters, Ferrer defeated Milos Raonic, former world no. 1 Juan Carlos Ferrero, former world no. 1 and tenth seed Andy Roddick, and Feliciano López on his way to the final that he lost to second seed Andy Murray in straight sets. At the 2011 ATP World Tour Finals, Ferrer's first match was against world no. 3 Andy Murray and the Spaniard won it. In his next match against world no. 1 Novak Djokovic, Ferrer won in just 75 minutes, securing his spot in the semifinals.