Kyle Busch and Denny Hamlin swapped the lead on pit road pitting on opposite pit roads. This time, it was Hamlin who beat his teammate off pit road. Kevin Harvick was tagged for his crew being over the wall too soon and restarted the race from the rear of the field. The race restarted on lap 133. Again deviating from recent Bristol norm, Denny Hamlin restarted on the bottom line and shot ahead of his teammate. The third caution of the race flew on lap 146 for a single-car wreck on the front stretch. Exiting turn 2, A. J. Allmendinger came down across the nose of Ricky Stenhouse, Jr., slid down the track and slammed the inside wall. The race restarted on lap 152. Teammate Kyle Busch drove by Denny Hamlin on the top side to take back the lead on lap 156. Hamlin pulled back up to him in the next eight laps, but was unable to get by him. Eventually, Busch began to pull away from the rest of the lead cars. Being caught being the lapped car of Josh Wise allowed Joey Logano to drive up to his outside, but pulled out in front and continued leading. Logano powered underneath Busch after he made slight contact with the wall to take the lead on lap 226. Debris in turn 3 brought out the fourth caution of the race on lap 250. Carl Edwards exited pit road with the lead. Justin Allgaier was tagged for speeding on pit road and restarted the race from the rear of the field. The race restarted on lap 258. Kyle Busch drove outside teammate Edwards to retake the lead on lap 282. Unfortunately, he was unable to build a gap as he was caught in heavy lap traffic. Carl reeled in Kyle to drive by him and take the lead on lap 304. He pulled to a one-second lead over Joey Logano. As is normal for Bristol, the lapped traffic slowed him down enough to allow Logano to reel in Edwards. David Ragan made contact with Kurt Busch and sent him into the turn 1 wall. Kyle Busch was running third when he made an unscheduled stop on lap 344. Logano ducked underneath Edwards and used the lapped car of Dale Earnhardt, Jr. as a pick to take the lead on lap 347. The lapped traffic allowed Carl to return the favor and retake the lead on lap 352. He cut down a tire, hit pit road from the lead and handed it back to Joey Logano.