The wing trained to maintain tactical proficiency and participated in exercises and aerial demonstrations from November 1948 to November 1949. It assumed an air defense mission in December 1949 and provided air defense in the northeastern United States until inactivated in February 1952, when it was inactivated and most personnel were transferred to the 4707th Air Defense Wing. Once again it provided air defense in the northeastern United States, from October 1956 to June 1957, but was non-operational from 1 July 1957 to 18 August 1957. On 1 April 1965, the wing was activated at Eglin Air Force Base, Florida and embarked on a program of tactical training operations to maintain proficiency. It operated a test support division, from July 1965 to December 1967, and a special test squadron, from December 1967 to April 1971, in support of tests for weapon systems, aircraft armament and munitions, and tactical procedures of the Tactical Air Warfare Center. The first Tactical Air Command McDonnell F-4D Phantom IIs assigned to a combat unit arrived at the 33rd at Eglin on 21 June 1966. The wing also provided F-4 replacement training from 15 December 1966 to 28 February 1967. Through deployment of combat-ready tactical components, with personnel and equipment transferred to Pacific Air Forces (PACAF) units upon arrival, the wing provided fresh aircraft and aircrews for the forces in Southeast Asia and in Korea. The wing also transferred two of its combat-ready squadrons to PACAF, the 25th Tactical Fighter Squadron in May 1968 and the 4th Tactical Fighter Squadron in April 1969. The wing's last combat-ready squadron, the 58th Tactical Fighter Squadron, deployed to Southeast Asia for combat operations from April to October 1972 and again from June to September 1973. The wing supported the 4485th Test Squadron of the Tactical Air Warfare Center in weapon systems evaluation program tests from January to December 1973, and periodically thereafter until July 1978. Aircrews ferried F-4Es to Israel in October 1973. The wing augmented intercept defense forces of the North American Air Defense Command (NORAD) from 1 January 1976 to 15 January 1979 and from 4 January 1982 to 5 April 1982. While awaiting delivery of McDonnell Douglas F-15 Eagles, the 60th Fighter Squadron conducted F-15 mission qualifications training for the 18th Tactical Fighter Wing (Kadena Air Base, Japan) from 15 July 1979 to 30 April 1980. The wing provided personnel and equipment to fly combat air patrols and air intercept missions for contingency operations in Grenada, from October to November 1983, and Panama, from December 1989 to January 1990.