Markey was named the Pac-10 Offensive Player of the Week for his efforts. In his second year, Markey ranked second on the team in rushing with 561 yards. He also ranked second on the team in all-purpose yards with 1,223 all-purpose and fourth on the team with 5 touchdowns. Markey played in all 12 games and started against USC. In the season-opener at San Diego State, he returned two kickoffs for 91 yards (including one for 71 yards) and also returned a punt 41 yards. His best performance of the season occurred in the Sun Bowl. In that game against Northwestern, Markey rushed for 161 yards on 24 carries and won co-MVP honors. Markey started all 13 of UCLA's games in 2006. On the year, he averaged 85.2 yards on the ground and 105.9 all-purpose yards per game. By the end of the season, he ranked 4th in the Pac-10 and 32nd nationally in rushing yards (85.15), and 8th in the Pac-10 and 56th in the NCAA in all-purpose yards (105.92). By the end of the season, Markey became the 14th Bruin to rush for 2,000 yards in his career. Markey also led the team with 35 receptions and became the first Bruin since Kermit Alexander in 1962 to lead the team in both rushing and receptions in a single year. His 1,107 rushing yards on the year ranks 11th on UCLA's single-season list. That was also the most by a Bruin since 2001. It was in 2006 that Markey was named a member of the Doak Walker Award Pre-Season Watch List, UCLA's co-Most Valuable Player, and received All-Pac-10 honorable mention. He had a career-high 208 yards on 23 carries against Rice: the 14th highest total in school history. In that game he had 4 runs of at least 20 yards (43, 36, 31, and 20) and 3 others of at least 10 yards. Markey entered his senior season as one of the top running backs in the Pac-10 Conference. On the year, he rushed for 715 yards (4.1 average) and three touchdowns, and his average of 59.6 yards per game was 11th in the Pac-10. He had his best game of the year against Washington, in which he rushed for 193 yards (the second-highest total of his career) and one touchdown on just 14 carries.