Amos Hershey, a professor of political science at Indiana University, bought the house from the Wylie heirs in 1915. While he and his wife Lillian lived there, they undertook the first significant changes to the building. In addition to modernizing the kitchen and bathrooms and adding a furnace, they enclosed the second story porch, removed the ground floor pantries and screened in the front porch on the first floor. They also added pediment awnings over the front door and a small slanting roof over the east door to the kitchen. In 1947 Herman B Wells, then president of Indiana University, helped the university acquire the house from Dr. Hershey's widow, who continued to live there until 1951. Between 1951 and 1959 the house was home to Indiana University Press. Then in the period between 1960 and 1965, major restorations of the house were conducted aimed at bringing it back to its original configuration. In attempting to remove all features added to the house since its construction, the restoration removed at least one feature now believed to be original to the house, a small back porch. Today, known as Wylie House Museum, the building is a historic house museum that presents the house as it would have looked prior to 1860. With an inventory from 1859 as a guide it is furnished with a combination of Wylie family heirlooms and period pieces.