As can be seen from the formula, the need to evaluate derivatives of arbitrarily high orders renders this formula impractical for most purposes. With the advent of powerful personal computers, the main efforts to use this formula have come from dealing with approximations or asymptotic analysis of the Inverse Laplace transform, using the Grunwald–Letnikov differintegral to evaluate the derivatives. Post's inversion has attracted interest due to the improvement in computational science and the fact that it is not necessary to know where the poles of "F"("s") lie, which make it possible to calculate the asymptotic behaviour for big "x" using inverse Mellin transforms for several arithmetical functions related to the Riemann hypothesis.