The boat left St. Nazaire on 25 October 1941 and returned on 26 November. The patrol was unsuccessful. She attacked convoy HG 76 in the North Atlantic, north-east of the Azores, which was made up of 32 cargo ships and escorted by five destroyers, seven corvettes and one aircraft carrier, sinking the 3,324-ton Norwegian merchant ship "Annavore" on 21 December 1941. "U-567" was herself sunk later the same day at by depth charges dropped by and - there were no survivors from her crew of 47. "U-567" took part in five wolfpacks, namely.