The highway between MD 14 in East New Market and Poplar Street in Hurlock was constructed on a new alignment as a county highway in 1939. MD 392 was extended west from Finchville to MD 331 in Hurlock in 1951 following the relocation and reconstruction of the existing county highway between Harrison Ferry and Hurlock. New highway was constructed between MD 331 and Poplar Street south of Hurlock and between MD 14 and MD 16 south of East New Market in 1956 and 1957, respectively. These bypasses and the reconstruction of the East New Market–Hurlock road were part of the extension of MD 392 to East New Market in 1957. The present Harrison Ferry Bridge was constructed in 1999. MD 392A is the unsigned designation for a segment of Poplar Street adjacent to its southern terminus at MD 392 in Hurlock.