While there details were arranged for the flight of six PBY's from Argentia to Iceland via Bluie West One, the Comanche taking communication guard of planes in the flight. On 8 May she proceeded to Ivigtut to guard the cryolite mines there, remaining until 20 May 1942. The rest of May, 1942, she was employed in ice-breaking activities in Sondre Stromfjord and then in towing the Raritan from Godthaab to Bluie West One. Arriving on the 28th she met the in Tungliarfik Fjord and escorted the transport to Bluie West One, arriving there on 3 May 1942. On 6 June, she patrolled Weather Station "A" where she remained until 20 June 1942, being relieved by . From 25 June to 2 July she was on airplane guard at the mouth of Tungliarfik Fjord being relieved by the USS Bear. From 4 July to 17 July 1942, she relieved "Algonquin" on Weather Station "A" and after repairs to her steering gear she returned to Bluie West One. On 22 July 1942 Captain C. C. von Paulsen, USCG, (Senior Officer Present Afloat, Greenland) and Ensign J. Starr, USCG, came on board "Comanche" and she proceeded to Julianehaab whence on the 23rd pilots S.T. Sorenson and Julius Carlson came on board to cruise through the inside passage of southern Greenland, taking soundings and making observations of uncharted areas. From 29 July 1942 to 7 August 1942, "Comanche" met incoming convoys and relieved their escorts. Then she took on fuel and stores for the Ice Cap Station which was to be established on the east coast of Greenland and on the 13th embarked ten Army enlisted personnel and two civilians and their gear, leaving Ivigtut with the to escort "Dorchester" and SS "Alcoa Pilot" to Bluie East Two, where she arrived on the 17th. Here she took on more supplies for the Ice Cap Station and proceeding to Angmagssalik, three enlisted Army personnel departed while three Army officers came aboard. She departed on the 18th and proceeded down the east coast to an unnamed bay at 65° 03' N x 40° 18' W, which was to be the site of the Ice Cap Station. Arriving on the 18th the bay was named Comanche Bay in honor of the cutter "Comanche".