Jo-Anna Downey  Jo-Anna Downey (February 1, 1967—December 2016) was a multiple Canadian Comedy Award-nominated stand-up comedian. She was the host of two popular weekly Toronto, Ontario comedy shows, "Open Mike at Spirits" (since 1996) and "Standing on the Danforth". Downey suffered from amyotrophic lateral sclerosis since 2012 and ended her career by 2013. Downey died on December 1, 2016.