They posed a major threat to the Abenaki and Mohicans, while the Susquehannock briefly conquered the Lenape in the 1600s. The most devastating event of the century, however, was the Beaver Wars. From approximately 1640–1680, Iroquoian peoples waged campaigns which extended from modern-day Michigan to Virginia against Algonquian and Siouan tribes, as well as each other. The aim was to control more land for animal trapping, a career most natives had turned to in hopes of trading with whites first. This completely changed the ethnography of the region, and most large game was hunted out before whites ever fully explored the land. Still, afterward, the Iroquois Confederacy offered shelter to refugees of the Mascouten, Erie, Chonnonton, Tutelo, Saponi, and Tuscarora nations. In the 1700s, they would also merge with the Mohawk during the French-Indian War and take in the remaining Susquehannock of Pennsylvania after they were decimated in war. Most of these other groups blended in until they ceased to exist. Then, after the Revolution, a large group of them split off and returned to Ohio, becoming known as the Mingo Seneca. The current six tribes of the Iroquois Confederacy are the Seneca, Cayuga, Onondaga, Oneida, Tuscarora and Mohawk. The Iroquois fought for both sides during the Revolutionary War; afterwards many pro-British Iroquois migrated to Canada. Today, the Iroquois still live in several reservations in upstate New York. Meanwhile, the Lenape formed a close relationship with William Penn. However, upon Penn's death, his sons managed to take over much of their lands and banish them to Ohio. When the U.S. drafted the Indian Removal Act, the Lenape were further moved to Missouri, whereas their cousins, the Mohicans, were sent to Wisconsin. Also, in 1778, the United States relocated the Nanticoke from the Delmarva Peninsula to the former Iroquois lands south of Lake Ontario, though they did not stay long. Mostly, they chose to migrate into Canada and merge with the Iroquois, although some moved west and merged with the Lenape. In 1524, Giovanni da Verrazzano, an Italian explorer in the service of the French crown, explored the Atlantic coast of North America between the Carolinas and Newfoundland, including New York Harbor and Narragansett Bay.