The law can at times be very contentious, but Lou was always a gentleman." Chief Circuit Judge Donald Moran commented, "He was so well-respected throughout the state of Florida, not only for his civic work but as a lawyer. He was a humble person, a gentleman's gentleman." The cancer returned however, and four years after he was diagnosed, Frost died of complications after a long hospitalization. In 1975, Frost was honored by the National Legal Aid & Defender Association with their distinguished "Reginald Heber Smith Award". He received the Mary L. Singleton Justice, Peace and Social Harmony Award in 2001, and the D.W. Perkins Bar Association recognized him in 2004 for his "trail-blazing" dedication to hiring African-American lawyers. In 2006, the Florida Public Defenders Association named him recipient of the "L. Clayton Nance Award". Frost commented, "It is a distinct honor to be recognized in the same group with former governors Farris Bryant and Leroy Collins and State Supreme Court Justices (B. K.) Roberts and Adkins and Sandy D'Alemberte. It is overwhelming for me. To be listed among those people as worthy of this award is the pinnacle of my career." That same year, the Criminal Law Section of The Florida Bar bestowed the Selig Goldin Award in recognition of his distinguished career.