Locally throughout this period, the Church played an important role. John II (Giovanni of Siena), Cardinal and Bishop of Viviers (1073–1095), accompanied Pope Urban II to the Council of Clermont. It was later held in fief by the Counts of Toulouse, who lost it to the French crown in 1229. In 1284, with the Cistercian Abbey of Marzan, Philip IV established Villeneuve de Berg, and by the treaty of 10 July 1305 Philip IV of France obliged the bishops of Vivarais to admit the sovereignty of the Kings of France over all their temporal domain. The realm was largely ignored by the Emperors and was finally granted to France as part of the domain of the Dauphin, the future Charles VII of Valois in 1308. During this period, the Maillard family, as Counts of Tournon, were influential in the Ardèche. During the Hundred Years War, the area maintained its loyalty to the French crown, despite frequent attacks from the west. As a result of the reformation of John Calvin in Geneva, the Vivarais Ardèche was one of the areas which strongly embraced Protestantism partly as a result of the missionary activity of 1534 by Jacques Valery. During the following Wars of Religion (1562–1598), the Ardèche was considered a strategically important location between Protestant Geneva, Lyon and Catholic Languedoc. The region had prospered with the introduction of tobacco growing from America, and the agrarian experiments of Olivier de Serres, father of modern French agriculture. The influence of Protestant Lyon, and the growth of the silk industry, thanks to the planting of mulberry trees, had given the burghers of the Vivarais towns a certain independence of thinking, and with the support of powerful Protestant Huguenots, (the Comte de Crussol and Olivier de Serres), the Vivarais became a Protestant stronghold. As a result, it suffered many attacks and eight pitched battles between 1562 and 1595. In 1598, the Edict of Nantes put an end to these struggles. At that time, the Vivarais had over 75 Protestant churches and five fortified strongholds with permanent garrisons. However, the problems of the area were not over. In 1629, Paule de Chambaud, daughter of the Huguenot lord of Privas, chose instead to marry a Catholic, the Vicomte de l'Estrange, who supported the persecution of Protestants by Cardinal Richelieu.