Prominent visitors to the property include explorer James Backhouse as well as Governors Macquarie (who granted and named the property), Darling, and Fitzroy as well as Governor, Lord Belmont who leased the property as his summer residence. Conrad Martens painted the property in 1836. The place is important in demonstrating aesthetic characteristics and/or a high degree of creative or technical achievement in New South Wales. The aesthetic significance of Throsby Park Historic Site is high. The homestead is set in cultivated gardens on a hill with vast open vistas over the sweeping rural landscape. The associated outbuildings, separated from the homestead in their own precinct add to the historic context of the site. When viewed as a whole, the homestead and its associated outbuildings, its natural setting and landforms with cultivated gardens and pastures is evocative of its early 19th century origins and appearance. Possibly the work of John Verge, Throsby Park House is a significant architectural milestone in a progression towards an Australian rural residential form which was a combination of the country house, villa and cottage forms. It is a compromise between English architectural fashion, the climate, available building resources and the wealth and social aspirations of the Throsby family. The place has strong or special association with a particular community or cultural group in New South Wales for social, cultural or spiritual reasons. Throsby Park Historic Site is of state significance as the first property developed outside the County of Cumberland and is an important milestone in opening up the Southern Highlands and the Berrima District. The property is of regional significance because of its association with the development of the Moss Vale district, in particular the establishment of Bong Bong and Berrima. It is also linked to the construction of Christ Church and the Royal Oak Inn at Bong Bong, as well as to the establishment of Bong Bong Picnic Race Club and the Moss Vale Jockey Club. It is also of ongoing significance to the descendants of the Throsby family. The place has potential to yield information that will contribute to an understanding of the cultural or natural history of New South Wales. Throsby Park Historic Site contains numerous archaeological deposits, standing structures and features, which have the potential to provide insights into early colonial mixed farming operations and associated subsistence activities and into the lifestyle of wealthy colonial families of the period. The extant buildings and features have the potential to demonstrate period construction techniques and materials. The place possesses uncommon, rare or endangered aspects of the cultural or natural history of New South Wales.