The Snake River Plain forms one of the only relatively easy paths across the main Rocky Mountains for many hundreds of miles, allowing Native Americans both east and west of the mountains to interact. As a result, the Shoshone centered on a trading economy. According to legend, the Nez Perce tribe was first founded in the valley of the Clearwater River, one of the Snake River's lowermost major tributaries. At its height, there were at least 27 Nez Perce settlements along the Clearwater River and 11 more on the Snake between the mouth of the Clearwater and Imnaha Rivers. There were also villages on the Salmon River, Grande Ronde River, Tucannon River, and the lower Hells Canyon area. The Snake River's annual salmon run, which was estimated at that time to exceed four million in good years, supported the Nez Perce, who lived in permanent, well-defined villages, unlike the nomadic southeastern tribes along the Snake River. The Nez Perce also were involved in trade with the Flathead tribe to the north and other middle Columbia River tribes. However, they were enemies to the Shoshone and the other upstream Snake River tribes. The Shoshone or Shoshoni were characterized by nomadic groups that took their culture from the earlier Bitterroot culture and Great Basin tribes that migrated north via the Owyhee River. They were the most powerful tribe in the Rocky Mountains area, and were known to many Great Plains tribes as the "Snakes". In the 18th century, Shoshone territory extended beyond the Snake River Plain, extending over the Continental Divide into the upper Missouri River watershed and even further north into Canada. A smallpox epidemic brought by European explorers and fur trappers was responsible for wiping out much of the Shoshone east of the Rocky Mountains, but the Shoshone continued to occupy the Snake River Plain. Eventually, the Shoshone culture merged with that of the Paiute and Bannock tribes, which came from the Great Basin and the Hells Canyon area, respectively. The Bannock brought with them the skill of buffalo hunting and horses they had acquired from Europeans, changing the Shoshone way of life significantly. The Lewis and Clark Expedition (1804–06) was the first American group to cross the Rocky Mountains and sail down the Snake and Columbia rivers to the Pacific Ocean. Meriwether Lewis supposedly became the first American to sight the drainage basin of the Snake River after he crossed the mountains a few days ahead of his party on August 12, 1805, and sighted the Salmon River valley (a major Snake tributary) from Lemhi Pass, a few miles from the present-day site of Salmon, Idaho.