Soon after in 2004, Favre's wife, Deanna Favre, was diagnosed with breast cancer. Following aggressive treatment through 2004, she recovered. She created The Deanna Favre Hope Foundation which supports breast cancer education and women's breast imaging and diagnosis services for all women, including those who are medically underserved. In late August 2005, Favre's family suffered another setback: Hurricane Katrina blew through Mississippi, destroying his family's home there; however, none of his family members were injured. Brett and Deanna's property in Hattiesburg, Mississippi was also extensively damaged by the storm. Favre elected to continue to play in the 2005 season. For the 2005 season, despite throwing for over 3,000 yards for a record 14th consecutive time, Favre had a below average season with only 20 touchdown passes and a league-leading 29 interceptions. The loss of guards Marco Rivera and Mike Wahle to free agency along with key injuries to Javon Walker, Ahman Green, Bubba Franks, among others, hampered Favre and the team. His passer rating was 70.9, 31st in the NFL and the worst single season rating of his career. After the disappointing season, many speculated that Favre would retire. However, on April 26, 2006, Favre announced that he would remain with the team for the 2006 season. Despite earlier comments that the 2006 season would be his last, Favre announced in a press conference on May 6, 2006, that he had not ruled out the possibility of returning beyond the 2006 season. In the 2006 season, Favre suffered his first career shutout against the Chicago Bears in a 26–0 loss in Week 1. Later in the season, the New England Patriots shut out the Packers in a game where he was injured before halftime and could not complete the game. On September 24, he became just the second quarterback in NFL history to record 400 touchdown passes (Dan Marino being the first). He connected with rookie wide receiver Greg Jennings on a 5-yard pass that Jennings turned into a 75-yard touchdown play during a win against the Detroit Lions. He became the first player ever to complete 5,000 passes in his career. On December 31, 2006, the Packers played their last game of the season, winning 26–7 in the second game against the Chicago Bears. It was his 22nd career win versus the Bears, moving him to an all-time record of 22–8. Overall, Favre finished the 2006 season with 3,885 passing yards, 18 touchdowns, and 18 interceptions.