Trauma Center: Second Opinion  Trauma Center: Second Opinion is a video game developed by Atlus for the Wii. The second entry in the "Trauma Center" series, "Second Opinion" is a remake of the Nintendo DS title "" (2005). The game was released in North America and Japan in 2006 by Atlus as a console launch title, and in other regions in 2007 by Nintendo. Set in a near future where medical science can treat previously incurable diseases, the story follows young surgeon Derek Stiles as he uses his mystical "Healing Touch" to treat a new disease dubbed GUILT. "Second Opinion" expands on the original narrative through the perspective of Naomi Kimishima, another doctor with the Healing Touch. Gameplay combines surgical simulation with a story told as a visual novel, with operations and control options reworked for the Wii hardware. The game began development in early 2006. Production was stressful due to a small team and tight development period. The character Naomi was added to help set the game apart from the DS original. The localization was done by Atlus USA, who focused on tightening the original script and merging it with the new narrative. The game was positively reviewed by journalists, who praised its implementation of the Wii control scheme. It was also a commercial success, selling over 400,000 units overseas. "Trauma Center: Second Opinion" is a video game that combines surgical simulation gameplay with storytelling using non-interactive visual novel segments using static scenes, character portraits, and text with rare voice clips. "Second Opinion" is a remake of "" for the Nintendo DS (DS). Players take on the roles of original protagonist Derek Stiles and new character Naomi Kimishima. The two are surgeons with a mystical ability called the Healing Touch. Each operation tasks players with curing the patient of their ailment within a time limit. Missions can be played on different difficulty settings. Surgery takes place from a first-person view. Operations range from treating surface wounds and extraction operations—carried over from the original—to new operations including organ transplants and repairing broken bones. Different surgical tools are required for different operations and injuries; players may need to drain blood pools obstructing the operating area, use a surgical laser to treat small tumors or boils, forceps to close wounds, and sutures to sew up both wounds and incisions. The player must frequently apply antibiotic gel to treat minor injuries and prevent infection. Actions during surgery are guided using the Wii Remote and Nunchuk. The Wii Remote being used for many actions including stitching up wounds and using the scalpel, filling the role of the stylus from the DS original.