Wallace later wrote Kennedy, "at no time in our history have so many tens of millions of people been so completely enthusiastic about an inaugural address as about yours". In 1962, he delivered a speech commemorating the centennial anniversary of the establishment of the Department of Agriculture. He also began a correspondence with President Lyndon B. Johnson regarding methods to alleviate rural poverty, though privately he criticized Johnson's escalation of American involvement in the Vietnam War. In the 1964 election, Wallace returned to the Democratic fold, supporting Johnson over Republican nominee Barry Goldwater. Due to declining health, he made his last public appearance that year; in one of his last speeches, he stated, "We lost Cuba in 1959 not only because of Castro but also because we failed to understand the needs of the farmer in the back country of Cuba from 1920 onward. ... The common man is on the march, but it is up to the uncommon men of education and insight to lead that march constructively". Wallace was diagnosed with amyotrophic lateral sclerosis (ALS) in 1964. He consulted numerous specialists and tried various methods of treating the disease, stating, "I look on myself as an ALS guinea-pig, willing to try almost anything". He died in Danbury, Connecticut, on November 18, 1965. His remains were cremated and the ashes interred in Glendale Cemetery in Des Moines, Iowa. Due to his successful business career and wise investments, he left an estate valued at tens of millions of dollars. In 1913, Wallace met Ilo Browne, the daughter of a successful businessman from Indianola, Iowa. Wallace and Browne married on May 20, 1914, and had three children. Henry Browne was born in 1915, Robert Browne was born in 1918, and Jean Browne was born in 1920. Wallace and his family lived in Des Moines until Wallace accepted appointment as secretary of agriculture, at which point they began living in an apartment at Wardman Park in Washington, D.C. In 1945, Wallace and his wife purchased a 115-acre farm near South Salem, New York known as Farvue. Ilo was supportive of her husband's career and enjoyed serving as Second Lady of the United States from 1941 to 1945, though she was uncomfortable with many of Wallace's Progressive supporters during his 1948 presidential campaign. Wallace and Ilo remained married until his death in 1965; she lived until 1981. In 1999, Wallace's three children sold their shares in Pioneer Hi-Bred to DuPont for well over $1 billion. Wallace's grandson, Scott Wallace, won the Democratic nomination for Pennsylvania's 1st congressional district in the 2018 elections, but he was defeated by Republican incumbent Brian Fitzpatrick in the general election.