The Enaton was sacked during the Persian conquest of Egypt in 619, but survived the Arab conquest of Egypt in 641. The Persian sack suggests that the Enaton was by that time quite wealthy. Although the Enaton occasionally benefited from Muslim rule in Egypt, it never regained its former glory. It seems to have maintained its federal constitution for some time, but by the 11th century it had become a single monastery. It maintained its international character and reputation for scholarship longer. It remained an active monastic centre until the 14th or 16th century. Its later history, however, is obscure. In 689, the hegumen John was considered for the patriarchate. The one actually elected, Simeon I, had been an oblate serving at the tomb of Severus. He was buried in the same church as Severus. The next patriarch, Alexander II, was also a monk from the Enaton. By the time of the Patriarch Mark II in the late 8th century, there was a tradition that a new patriarch should visit the Enaton. This tradition was abandoned by the 15th century. By the 11th century, the Enaton was a single monastery dedicated to Severus of Antioch. Owing to Severus and the Syriac influence, it had a Jacobite orientation. In 1066, the hegumen John ibn Tirus was considered for the patriarchate. The monastery may have suffered from Bedouin raids during the patriarchates of Shenouda II (1032–1046) and Christodoulos (1047–1077). The monastery had only about forty monks in residence during this period, a sharp decline from its heyday. "The Miracles of Abba Mina", possibly written as early as 1363, was attributed in the 18th century to a certain Archimandrite Mardarius of Gabal al-Niaton, perhaps a corrupted reference to the Enaton. Al-Maqrizi wrote in the 15th century that the monastery of Dayr al-Zujaj was also known as al-Hanatun and was dedicated to Bu Gurg the Elder, Saint George. He is the last author to write of the monastery as still existing. The monastery appears on western European maps from the 14th through 17th centuries, but it may have bee merely a placename by then. The decline of the monastery probably owes something to the disruption of the coastal traffic during the Crusades and the desertification of Lake Mareotis. Dates are floruits.