Thus, although the neuroscientific approach is still in development, there is some neurological evidence of the link between social relationships and health. Based on what has been described above, it is important to elaborate interventions that improve physical and mental health by enhancing social relationships. These interventions could target different contexts (work, friendship, etc.) or different populations (young or aged people, married or single, etc.). Identifying the context and the population targeted is important because some individuals are more at risk than others overall or in some specific contexts. For instance, it is well described that students are a population categorized at risk of health problems, and among students, black students are more concerned by mental health problems (Lindsey et al., 2019). In this example, it is important to design an intervention that is specific for black students, which is slightly different from the one designed for students in general. According to Kawachi and Berkman (2001), some interventions have been proposed, with some success, to improve social ties: support group interventions, one-to-one support interventions, and interventions to enhance natural networks. Due to the variability of each intervention, even in the same category of intervention, that has been proposed in the literature, it is not feasible to draw generalized conclusions. However, by targeting specific contexts and specific populations, some studies found that these kinds of interventions can be effective to improve physical or mental health. For instance, Leung, Orrell, and Orgeta (2015) reviewed the literature testing the positive effect of social support group interventions for people diagnosed with dementia and found out they have small benefits on depression and the quality of life of the patients. However, the trials included in this review are too limited (only two studies that fit the inclusion criteria), they are heterogeneous, meaning that it is difficult to conclude on the effect of social support group interventions on this context, and more randomized controlled trials will be needed. Four interventions have been identified by Masi and collaborators (2011) to reduce loneliness: improving social skills, enhancing social support, increasing opportunities for social interaction, and addressing abnormal social cognition. Increasing opportunities for social interaction and enhancing social skills could have a bigger impact on social isolation, whereas improving social skills and addressing abnormal social cognition focus on loneliness. Improving social skills refers to giving methods to better interact with others. Among lonely college students, this kind of intervention was positively associated with less loneliness. The goal of the interventions that address abnormal social cognition is that lonely individuals learn that automatic negative thoughts are not facts, but hypotheses. For seniors, interventions could be home-visit or telephone contacts, group interventions/activities, etc.