Saponin is one of the major compounds of the leaf. 24 beta-ethylsterols, clerosterol and 22-dehydroclerosterol, 24-methyl-sterols (24-methylcholestanol, 24-methylcholesterol, 24-methyl-22-dehydrocholesterol, and 24-methyllathostero) and 24 beta-ethyl-22-dehydrocholestanol are found in the seeds. Scutellarin and hispidulin-7-O-glucuronide are present in the leaf. Poriferasterol and stigmasterol are the components of the aerial parts. "Clerodendrum infortunatum" is used in Ayurvedic and Siddha traditional medicines. Fresh leaves are given for diarrhea, liver disorders, and headache. The leaf and root are used as antidandruff, antipyretic, ascaricide, laxative, vermifuge, anticonvulsant, antidiabetic, and for gravel, malaria, scabies, skin diseases, sores, spasm, scorpion sting, snake bite, and tumors. In many traditional practices the leaves and root are widely used as antihyperglycemic.