Research Focus  The Hormones and Cancer Group's strong links to the hospital departments of Endocrinology and Oncology promote ongoing interactions with cancer surgeons, including the research training of junior surgeons, provide constant opportunities for the cross-fertilisation of the group's research between the laboratory and clinic. The Institute of Bone & Joint Research (IBJR) was established in 1999 to provide an Institute devoted to advancing the understanding of disorders and diseases of the musculoskeletal system, their diagnosis and treatments. At the RNSH, basic and clinical research within the IBJR are presently undertaken in the Departments of Orthopaedics and Rheumatology and their associated laboratories. The IBJR joined the Kolling Institute of Medical Research in 2006, with the objective of improving the collaboration and cross-fertilisation between researchers in different disciplines to advance bone and joint research on the campus. IBJR primary objectives are:  Apart from supporting research activities in the above areas, the Institute also disseminates recent advances in the understanding of the musculoskeletal sciences by organising regular public seminars and scientific symposia where leading specialists present their latest research findings. The Bone and Joint group investigates diseases of the bone, cartilage, tendons, ligaments and joints, with particular research interests in osteoarthritis, rheumatoid arthritis, osteoporosis and spinal diseases. Laboratories in IBJR  Researches cardiovascular disease with particular strengths in cellular electrophysiology and the use of translational models to understand heart failure and repair mechanisms. Head of Research: Dr Greg Fulcher  Headed by Professor Carolyn Sue, the Neurogenetics group studies disease mechanisms involved in inherited neurological disorders with a particular interest in mitochondrial function and movement disorders (e.g. Parkinson’s disease). Established in 1990, the Pain Management Research Institute (PMRI) is a joint initiative between the University of Sydney and Royal North Shore Hospital. PMRI is a division of the Kolling Institute of Medical Research, which has the broad goal of improving human health. Headed by Professor Michael Cousins, Pain Management aims to develop treatments for a range of severe, persistent pain problems (e.g. due to injury, cancer, inflammation). This involves basic research to understand the structural, molecular and physiological changes in the nervous system, and clinical and epidemiological studies. PMRI consists of a multidisciplinary group of health professionals and research staff who are collaborating in education and research to improve pain treatment in adults and children.