She then made a brief appearance in the premiere episode of "Big Brother 15", giving her sister Elissa a key to the Big Brother house. She also appeared later in the season, offering her opinion on the season and her sister's gameplay. She appeared in a similar role during the closing stages of the second season of "Big Brother Canada" and "Big Brother 16", discussing the game and prospects of the remaining HouseGuests. In "Big Brother 20", she returned to the house to host a Power of Veto competition. In being nominated for eviction five times  and still making it to the end to win the $500,000 prize. Additionally, in winning the third part of the final Head of Household competition (which she won by providing the only correct answers), she tied Janelle Pierzina's record of multi-seasonal HoH competition wins at six. She is also tied with Drew Daniel, Pierzina, Hayden Moss, Ian Terry, Aaryn Gries and Caleb Reynolds for the most sole HOHs won in a season at four. The day following her "Big Brother" win, Reilly and Villegas appeared on CBS talk-show "The Talk", co-hosted by "Big Brother" hostess Julie Chen. Reilly discussed her experiences on "Big Brother" during her appearance and won a vacation to Aruba, after competing in a "Big Brother" style challenge. In late 2011, photographs appeared on the internet suggesting that Reilly and Villegas are competing as a team on season 20 of "The Amazing Race". In January 2012, CBS confirmed that Reilly and Villegas would compete on season 20 of "The Amazing Race". In 2013, Reilly began appearing in a Hollywood production of "The Real Drunk Housewives of San Fernando Valley", a musical parody of the television show. Reilly and then-fiancé Brendon Villegas were on the season 20 of "The Amazing Race", which premiered on February 19, 2012. They ended up in 3rd place out of 11 teams in the final leg, losing to border patrol agents of Art Velez and J.J. Carrell (runners-up) and the married couple Rachel and Dave Brown, Jr. (winners). During the competition, Reilly was shown breaking down into tears several times, and also got into arguments with competitor Vanessa Macias. After their marriage, Reilly and Villegas participated in "The Amazing Race" once more as part of its second All-Stars edition. Through the course of the season, the two won three legs, earning each and a trip to the Great Barrier Reef.