Wentz was in a multi-episode arc of the show "One Tree Hill", appearing at Tric (the local all-ages club in Tree Hill) with the entire band. The band first appeared in an episode "An Attempt to Tip the Scales", where they played their single "Dance, Dance" and went on to appear on Peyton and Ellie's (also One Tree Hill's album) tribute album, "Friends with Benefit" to support cancer awareness. Pete made his first solo cameo in the episode "When It Isn't Like It Should Be" as the romantic interest of Peyton Sawyer, a senior at Tree Hill who had booked the band to play at Tric. He also made a brief cameo appearance in the show "Californication". On February 6, 2008, it was reported that Wentz was the leading candidate for writer Diablo Cody's follow-up film to "Juno", "Jennifer's Body". The role ended up going to Adam Brody. On February 24, 2008, Wentz appeared in comedian Jimmy Kimmel's video "I'm Fucking Ben Affleck" as a chorus member (along with many other celebrities). The video was in response to one made by Kimmel's then-girlfriend, Sarah Silverman, "I'm Fucking Matt Damon". In 2009, he made a cameo appearance as himself in "Degrassi Goes Hollywood". In 2016, he made a guest appearance on the Nickelodeon series, "School of Rock". In 2012, he appeared as himself on "The Eric Andre Show". In 2017, Wentz guest starred, with his bandmates, in Cartoon Network's "Teen Titans Go!" playing himself in the first, third and fourth parts of "The Night Begins to Shine". Their cover of the title song from the special was commercially released. Wentz hosts the TV show "Best Ink". Wentz directed a music video for the song "If It's Love" by American rock band Train. He was a contestant in an episode of the Nickelodeon game show "Double Dare". In 2020, he made a guest appearance on 2 episodes of the Nickelodeon show, "All That". Wentz has bipolar disorder, and has taken medication for it since he was eighteen. In February 2005, Wentz attempted suicide by taking an overdose of the anxiety medication Ativan, and as a result, spent a week in the hospital. Commenting on the event to a magazine, he said:  The suicide attempt was put into song form, "7 Minutes in Heaven (Atavan Halen)" and released on their album, "From Under the Cork Tree".