In 2008, Prasanna was seen in three films. He starred in Siddique's comedy thriller "Sadhu Miranda". His role of a modern-day villain was a huge hit in Mysskin's film "Anjathey". His negative role was critically acclaimed and fetched him a nomination at the 56th Filmfare Awards South in the Best Supporting Actor category. He played the lead in Arun Vaidyanathan's "Achchamundu! Achchamundu!" (2009) opposite Sneha that dealt with the subject of paedophiles. It received rave reviews, and was very well received internationally, but failed at the domestic box office. "Manjal Veyil", yet another flick was a big flop. During the period, he also worked as a voice actor, speaking dubbing for Aryan Rajesh in Cheran's "Pokkisham" on the insistence of the director. Then, alongside Sibiraj as antagonist, he starred in Shakthi Soundar Rajan's "Naanayam" as a protagonist produced by S.P.B. Charan's Capital Film Works. In recent times, Prasanna has been losing out on more offers. Earlier, he had signed up for a film titled "Naikkutty", produced by V. Z. Durai, but he stepped out due to unknown reasons. Again in "Bale Pandiya", directed by Siddharth Chandrasekhar, Prasanna was replaced by Vishnu Vishal. He was seen in a cameo appearance in Venkat Prabhu's comedy film "Goa", followed by a supporting role as a local gangster in "Baana Kaathadi". A review from "Times of India" wrote that "with his eyes-to-die-for and underplayed violence, Prasanna easily steals the show". In 2011, he performed a lead role alongside director-actor Cheran in the thriller film "Muran". His character, a "spoiled brat" and son of a millionaire, again had negative shades. He was also approached for "Lucky Jokers", which he could not take due to his busy schedule with "Muran". He has been approached to play a vital role in Dileep's production "Akku Akbar". He dubbed for Ashwanth Thilak for Mani Ratnam's "Raavanan". During the filming of "Achchamundu! Achchamundu!"