The police, including Sergeant Hacker (Roger Gentry), escort Jack to the transplant center for this experiment they have been told about. The doctors are surprised to see a large African American being brought before them for this experiment, knowing full well that when Kirshner wakes up, he is not going to like what he sees. However, the doctors work around the clock to transplant Dr Kirshner's head onto Jack's body. After the operation, Kirshner wakes up, and Desmond tells him that the operation was a success. Desmond tells him that they had no other choice but to transplant his head onto the African-American's body, and that he would not have lived another day if they had not operated when they did. At that moment, Jack awakens and is angry and disturbed that Kirshner's head is on his body and tries to get up from the table, but Kirshner cries out for someone to sedate Jack, which Desmond does. Desmond tells him that he will keep the 'Jack' side heavily sedated all the time while Kirshner regains the power to move the body. Leaving Kirshner to rest, Desmond meets up with Dr. Williams again and tells him he needs his help. Williams is reluctant at first, but Desmond reassures him that his beliefs are not the same as Dr. Kirshner's and that his help is very much needed. Meanwhile, a nurse (Britt Nilsson) comes to administer a sedative to Jack's side of the body. Jack tricks the nurse into thinking he is asleep, and then injects her with the sedative instead and escapes, taking Williams with him/them. Williams drives the car under gunpoint by Jack and Desmond chases after them. Jack asks Williams if he can remove Kirshner's head from his body. Jack takes over driving and accidentally crashes the car, resulting in a flat tire. Kirshner then tries to appeal to Williams by offering him the accolades he has received by performing a successful transplant. Williams refuses the offer, as it would mean that he would have to remove Jack's head. Jack goes to his wife's house; Lila (Chelsea Brown) is not that pleased to see him because of Kirshner's head on his body. While Jack is sleeping, Kirshner finds out that he can now control the body almost fully. Jack, Kirshner, Williams and Lila sit down for dinner. Lila asks what it will take to take Kirshner's head from Jack's body.