"Clayoquot" sank the ship with gunfire and depth charges. On 10 September she was returning to Gaspé, Quebec after escorting a convoy to Rimouski with the corvette nearby when "Charlottetown" was hit by two torpedoes. "Clayoquot" searched for, but was unable to find the submarine. During depth charge attacks on possible targets, "Clayoquot"s radio was knocked out and prevented the ship from informing command of the corvette's loss. She returned to the site of the sinking and was able to rescue 55 survivors, taking at least three and a half hours to complete. In October 1942 she joined Sydney Force. On 29 December 1942 "Clayoquot" was sent for a major refit that took her from Halifax to Liverpool, Nova Scotia, to Pictou. The refit was completed in May 1943. After working up, she rejoined Sydney Force. In January 1944 she was assigned to as an officer training vessel for anti-submarine warfare. After ten months of training service, she was reassigned to Halifax Force. While sweeping for submarines near Sambro Island Light on 24 December 1944 in preparation to escort a convoy, "Clayoquot" was hit aft by a torpedo fired by . She sank quickly and eight lives were lost. There had not been enough time to disarm the depth charges kept ready, which detonated as the ship sank causing injuries among the surviving crew, which were picked up by the corvette . The frigate and sister ship which had been accompanying "Clayoquot", were also targeted by the U-boat, but the torpedoes detonated before doing damage to the ships. A large search force was sent out to deal with the U-boat however they were not successful in finding the submarine.