The inflorescences shoot from the apexes of the last one or two pseudobulbs and are apical, short and pending, bearing just one flower which faces the ground. The flowers are comparatively large in relation to the plant size, with segments that do not completely open. The petals and sepals are white and oblong, the sepals slightly larger than the petals, sometimes with the apexes reflected. The petals are similar to the sepals but slightly narrower at the base. The labellum is strong yellow margined of bright purple; at the base it is fused to the column base forming a narrow spur shaped nectary; it is internally slightly pubescent and has a thick callus that splits in five digitate keels on the disk; the central lobe is partially saccate and has two longer fringes at the apex. The column is white almost cylindrical without any appendages. The anther, contrasting to the flower, is very bright purple, apical, bearing six pollinia, four small and two large, hold by a caudicle similar to the ones of "Leptotes". "Loefgrenianthus blanche-amesiae" blooms between the middle of the spring and early summer and the flowers last for about a week. Its pollinators are unknown, however, because of its color, they may be night moths, or bees due to the flowers structure. The Danish Botanist Johan Albert Constantin Löfgren lived many years in Brazil where he was studying the flora of Minas Gerais State, painting watercolors of plants and was a director of Rio de Janeiro Botanical Garden. In 1896 while looking for new specimens on Serra da Mantiqueira, in Rio de Janeiro, he came across a small plant he did not recognize. At the time the Belgian Botanist Célestin Alfred Cogniaux was working on the noted Flora Brasiliensis of Carl Friedrich Philipp von Martius, an encyclopedia that described all plant species of Brazil known at the time. Therefore, trying to establish its identity, Loefgren sent the plant he found to Cogniaux, however, the specimen was lost and never recovered. In 1915 the professor Oakes Ames, botanist responsible for the herbarium of Harvard University, and his wife Blanche were traveling in Brazil and met Loefgren. Together they accidentally found, on the slopes of Itatiaia mountain, another specimen of the plant which had been lost almost ten years before.