Brody disease is suspected in people with the characteristic symptoms of this disorder (e. g. , peudomyotonia, myoglobinuria etc. . . ). In addition, people with this disease may have normal or slightly elevated creatine kinase levels. Click here to learn more about creatine kinase testing. A careful evaluation of muscle tissue samples obtained from muscle biopsy shows type 2 A and B atrophy with angulated fibers. Also, biochemical and immunological testing of the activity of certain proteins in the cell (i. e. , sarcoplasmic reticulum Ca ATPase) can also help confirm the diagnosis. 
How to diagnose Brody myopathy ?