What is the recommended target for INR control when using VKAs for patients with non-valvular AF?
For patients with non-valvular AF, when VKAs are used, the recommended target should be an INR level of 2.0-3.0, with attention to individual TTR, ideally 70%. If the TTR is sub-optimal (< 65-70%), additional measures should be implemented to improve INR control or consider an NOAC. When possible, experienced specialized anticoagulation clinics should be utilized for VKA and INR management.