What are the findings of the SHEP trial with regards to the target BP for elderly patients?
The SHEP trial found that a low diastolic blood pressure on treatment was associated with an increased risk of stroke, coronary heart disease and CVD. Furthermore, the risk of the primary outcome (all-cause death, non-fatal myocardial infarction and non-fatal stroke) progressively increased with a BP lower than 119/84mmHg, although taken alone, stroke risk did not increase with lower BP.