What are the principles guiding inclusion and extrapolation of the results of studies in secondary stroke prevention?
The principles guiding inclusion and extrapolation of the results of studies in secondary stroke prevention are: 1. The quality of the trial/trials was acceptable. (Ideally, stroke or TIA occurrence or recurrence was a prespecified end point, with clear protocols for assessing stroke end points.) 2. From a physiological perspective, the primary prevention strategy used in the study will likely be effective for secondary prevention. 3. Patients with ischemic stroke were included in the population studied when possible.