What is the balance of risks and benefits of using ACE-Is or ARBs for patients with reduced GFR but normal urinary albumin excretion?
There is some evidence that inhibitors of the renin angiotensin system might prevent an increase in particularly in the presence of higher and might also reduce cardiovascular risk, however, no RCTs have been performed in patients with reduced GFR but normal urinary albumin excretion. Therefore, it is difficult to determine the exact balance of risks and benefits of the use of ACE-Is or ARBs for such patients.