What is the recommendation for the timing of statin therapy in patients with an ischemic stroke?
It is reasonable to initiate statin therapy in-hospital among patients with an ischemic stroke who qualify for statin treatment. According to a retrospective cohort study, there is a high rate of adherence to statin therapy 3 months after hospital discharge. A meta-analysis of primarily observational studies found that in-hospital statin use was associated with good functional outcomes. Withdrawal of statins after ischemic stroke was associated with poor functional outcomes.