What changes in current practice are likely to be caused by the recommendations?
The recommendations are likely to lead to a change in current practice, with a reduction in warfarin use. The committee noted that this has been a prescribing trend over recent years and it may lead to a contraction in warfarin clinic services. The unit cost of direct-acting anticoagulants is greater than that for warfarin, so there is likely to be a resource impact from increased use of direct-acting anticoagulants.