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Changing late prognosis of acute myocardial infarction: impact on management of ventricular arrhythmias in the era of reperfusion and the implantable cardioverter-defibrillator. Circulation 2003; 107:941. 44. Malik M, Camm AJ, Janse MJ, et al. Depressed heart rate variability identifies postinfarction patients who might benefit from prophylactic treatment with amiodarone: a substudy of EMIAT (The European Myocardial Infarct Amiodarone Trial). J Am Coll Cardiol 2000; 35:1263. 45. Gillis AM. Prophylactic implantable cardioverter-defibrillators after myocardial infarction not for everyone. N Engl J Med 2004; 351:2540. https://www.uptodate.com/contents/incidence-of-and-risk-stratification-for-sudden-cardiac-death-after-myocardial-infarction/print 14/17 7/6/23, 1:39 PM Incidence of and risk stratification for sudden cardiac death after myocardial infarction - UpToDate 46. Armoundas AA, Tomaselli GF, Esperer HD. Pathophysiological basis and clinical application of T-wave alternans. J Am Coll Cardiol 2002; 40:207. Topic 1052 Version 30.0 https://www.uptodate.com/contents/incidence-of-and-risk-stratification-for-sudden-cardiac-death-after-myocardial-infarction/print 15/17 7/6/23, 1:39 PM Incidence of and risk stratification for sudden cardiac death after myocardial infarction - UpToDate GRAPHICS LVEF predicts six-month mortality after STEMI In a study of 1194 patients with an acute ST segment elevation myocardial infarction (STEMI) treated with thrombolysis, the resting left ventricular ejection fraction (LVEF) measured by radionuclide angiography (RNA) was a powerful predictor of six-month mortality. The highest risk group was those with an LVEF <30 percent. Data from Burns RJ, Gibbons RJ, Yi Q, et al. The relationships of left ventricular ejection fraction, end-systolic volume index and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis. J Am Coll Cardiol 2002; 39:30. Graphic 75743 Version 5.0 https://www.uptodate.com/contents/incidence-of-and-risk-stratification-for-sudden-cardiac-death-after-myocardial-infarction/print 16/17 7/6/23, 1:39 PM Incidence of and risk stratification for sudden cardiac death after myocardial infarction - UpToDate Contributor Disclosures Philip J Podrid, MD, FACC No relevant financial relationship(s) with ineligible companies to disclose. Peter J Zimetbaum, MD Consultant/Advisory Boards: Abbott Medical [Lead extraction]. All of the relevant financial relationships listed have been mitigated. Bernard J Gersh, MB, ChB, DPhil, FRCP, MACC Consultant/Advisory Boards: Bain Institute [CRO for trials involving Edwards percutaneous valve devices]; Cardiovascular Research Foundation [Data safety monitoring board (RELIEVE-HF Trial)]; Caristo Diagnostics Limited [Imaging and inflammation/atherosclerosis]; Philips Image Guided Therapy Corporation [Imaging]; Sirtex Med Limited [General consulting]; Thrombosis Research Institute [Data safety monitoring board (GARFIELD study)]. All of the relevant financial relationships listed have been mitigated. Nisha Parikh, MD, MPH No relevant financial relationship(s) with ineligible companies to disclose. Contributor disclosures are reviewed for conflicts of interest by the editorial group. When found, these are addressed by vetting through a multi-level review process, and through requirements for references to be provided to support the content. Appropriately referenced content is required of all authors and must conform to UpToDate standards of evidence. Conflict of interest policy https://www.uptodate.com/contents/incidence-of-and-risk-stratification-for-sudden-cardiac-death-after-myocardial-infarction/print 17/17