What is Fondaparinux?
Fondaparinux is a synthetic pentasaccharide that mimics the active pentasaccharide sequence of the natural anticoagulant heparin. It is used as an anticoagulant to prevent and treat deep vein thrombosis and pulmonary embolism. Fondaparinux has been found to be an effective alternative to low molecular weight heparins and unfractionated heparin in the management of heparin-induced thrombocytopenia. It has also been studied for its effects on human osteoblasts, placental transfer, and hirudin-based inhibitors.