What were the secondary outcomes of the EXTEND-IA TNK trial?
The secondary outcomes of the EXTEND-IA TNK trial included the mRS score at 90 days. In an analysis of secondary end points, tenecteplase resulted in better functional outcomes at 90 days on the basis of the ordinal shift analysis of the mRS score (common OR [cOR], 1.7 [95% CI, 1.0 2.8]; P=0.04) but less robustly for the proportion who achieved an mRS score of 0 to 1 (P=0.23) or 0 to 2 (P=0.06). sICH rates were 1% in both groups.