What is the effectiveness of transfusion therapy in reducing the risk of recurrent stroke in patients with sickle cell disease?
Several studies have shown that transfusion therapy can be effective in reducing the risk of recurrent stroke in patients with sickle cell disease. One study, by Pegelow et al. (658), found that transfusion therapy was associated with a significantly lower risk of recurrent stroke compared to no transfusion therapy. Similarly, a Cochrane Systematic Review (659) found that transfusions were associated with a reduction in the risk of primary and secondary stroke in people with sickle cell disease. Furthermore, a study by Ware et al. (660) found that transfusions were associated with a reduction in the risk of stroke recurrence in children with sickle cell disease. These findings suggest that transfusion therapy may be an effective method for reducing the risk of recurrent stroke in patients with sickle cell disease.