What evidence is there of an association between cannabis use and ischemic stroke?
Evidence of an association between cannabis use and ischemic stroke is increasing. A systematic review of cocaine identified an increased likelihood of ischemic and stroke for powder/paste cocaine (adjusted OR, 13.9 [95% CI, 2.8 69.0]) and crack cocaine (adjusted OR, 11.2). Acute ischemic stroke hospitalization is higher among cannabis users (OR, 1.41 [95%]), and the US Centers for Disease Control and Prevention identified that young adults (age, 18 44 years) with recent cannabis use have higher odds of stroke compared with nonusers (adjusted OR, 1.82 [95% CI, 1.08 3.10]), which increases among frequent cannabis users (>10 d/mo; adjusted OR, 2.45 [95% CI, 1.31 4.60]).