What are the benefits of rapid treatment with alteplase? 
In an analysis of 58353 alteplase-treated patients, treatment started more rapidly (evaluated in 15-minute increments) was associated with reduced in-hospital mortality (OR, 0.96 [95% CI, 0.95 0.98]; P<0.001), reduced symptomatic intracerebral hemorrhage (sICH) (OR, 0.96 [95% CI, 0.95 0.98]; P<0.001), increased independent ambulation at discharge (OR, 1.04 [95% CI, 1.03 1.05]; P<0.001), and increased discharge to home (OR, 1.03 [95% CI, 1.02 1.04]; P<0.001).