What risks are associated with taking MRAs?
The risks associated with taking MRAs include hyperkalaemia, renal impairment, and gynaecomastia. Hyperkalaemia and renal impairment may be underestimated due to the strict inclusion criteria of studies, and other studies suggest a higher rate of these adverse events in patients using MRAs. Gynaecomastia is also a potential risk, though the majority of patients do not experience this adverse event. It is recommended that patients are started on appropriate doses, have their potassium levels and renal function monitored regularly, and have appropriate dose adjustment if needed in order to manage these risks.