What are the recommendations for statin doses for CKD patients?
CKD patients are generally recommended to take lower doses of statins due to their increased risk of medication-related adverse events. The SHARP trial used lower dose simvastatin (20 mg/day) and added ezetimibe (10 mg/day) to achieve an average LDL-C reduction of about 0.83 mmol/l (32 mg/dl), during a 4.9-year period of treatment.