What are the clinical features and outcomes of women with unstable ischemic heart disease?
The clinical features and outcomes of women with unstable ischemic heart disease were observed from the Global Utilization of Streptokinase and TPA for Occluded Arteries (GUSTO-I) trial. The primary findings of the GUSTO-I trial showed that women presented with increased risk of cardiac death and had higher mortality compared to men. Additionally, women were more likely to experience higher heart rates, diabetes, hypertension, and previous MI, as well as lower hemoglobin levels. Furthermore, women were less likely to receive thrombolytic therapy when compared to men. The findings of the MERLIN-TIMI 36 trial showed that women with unstable ischemic heart disease had higher rates of heart failure and lower rates of revascularization when compared to men.