what are the Recommendations for Anticoagulation for Pregnant Women With
Mechanical Prosthetic Heart Valves?
For pregnant women with mechanical prostheses who require a warfarin dose >5 mg/d to achieve a therapeutic INR, dose- adjusted LMWH (with a target anti-Xa level of 0.8 to 1.2 U/mL at 4 to 6 hours after dose) at least 2 times per day for all 3 trimesters may be considered.