what are the Recommendations for Bridging Therapy During Interruption of Oral
Anticoagulation in Patients With Prosthetic Heart Valves
(Continued)?
F or patients who are undergoing invasive procedures and have 1) a mechanical AVR and any thromboembolic risk factor, 2) an older-generation mechanical AVR, or 3) a mechanical mitral valve replacement, bridging anticoagulation therapy during the preoperative time interval when the INR is subtherapeutic is reasonable on an individualized basis, with the risks of bleeding weighed against the benefits of thromboembolism prevention.