What are the major adverse effects of dihydropyridines?
The major adverse effects of dihydropyridines are related to vasodilation and systemic hypotension, including headache, dizziness, palpitations, and flushing. Many patients experience peripheral edema because of excessive arterial vasodilation unmatched to venous dilation. Verapamil can cause constipation that can be severe, particularly in the elderly.