What are some inherited disorders associated with increased risk of cerebral venous thrombosis?
Many coagulopathies are inherited as autosomal-dominant disorders, including protein C and S deficiencies, the factor V Leiden mutation, and various other factor deficiencies, which can lead to an increased risk of cerebral venous thrombosis. Inherited disorders of various clotting factors (ie, factors V, VII, X, XI, and XIII) are autosomal-recessive traits and can lead to cerebral hemorrhage in infancy and childhood.