What are the effects of intensive blood pressure treatment on cardiovascular events and mortality in patients with type 2 diabetes mellitus?
Studies have shown that intensive blood pressure treatment can reduce cardiovascular events and mortality in patients with type 2 diabetes mellitus. In the ACCORD BP and SPRINT trials, intensive systolic blood pressure lowering was associated with a significant reduction in the risk of cardiovascular events and all-cause mortality in patients with type 2 diabetes mellitus on standard glycemic control. In the HOT study, intensive blood pressure lowering was associated with a decrease in the progression of renal failure and a reduction in the risk of stroke. In the Syst-Eur trial, active treatment was associated with a significant decrease in stroke rates compared to placebo.