7/1/23, 12:40 AM Macrocytosis Pathway Feedback Search Clinical Topics Home Findings Macrocytosis Macrocytosis More common causes Alcohol use disorder Liver cirrhosis Vitamin B12 deficiency Acute erythroblastic leukemia Hypothyroidism Megaloblastic anemia Folate deficiency Less common causes Reticulocytosis Sideroblastic anemia Diamond-Blackfan anemia Hemolytic anemias Myelodysplastic syndrome Pernicious anemia Aplastic anemia Lesch-Nyhan syndrome https://web.pathway.md/findings/recqAX7rNcGB49U44 1/2 7/1/23, 12:40 AM Macrocytosis Pathway Uncommon causes Congenital dyserythropoietic anemia type 1 Methionine synthase deficiency Congenital dyserythropoietic anemia type 3 Hereditary orotic aciduria Congenital intrinsic factor deficiency https://web.pathway.md/findings/recqAX7rNcGB49U44 2/2