What are the effects of ramipril treatment in patients with acute myocardial infarction with clinical evidence of heart failure?
The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators found that ramipril treatment had beneficial effects on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The study, published in Lancet in 1993, showed that ramipril treatment reduced mortality by approximately one-third compared to placebo.