What is the recommended lipid-lowering therapy for patients with ischemic stroke and LDL cholesterol (LDL-C) >100 mg/dL?
For patients with ischemic stroke and LDL cholesterol (LDL-C) >100 mg/dL, the recommended lipid-lowering therapy is atorvastatin 80 mg daily to reduce the risk of stroke recurrence. This was found to be beneficial in reducing vascular events, including stroke in two randomized controlled trials, SPARCL (Stroke Prevention by Aggressive Reduction in Cholesterol Levels) and TST (Treat Stroke).