What are the recommendations for treatment of enterococcal endocarditis resistant to penicillin, aminoglycosides, and vancomycin?
The recommendations for treatment of enterococcal endocarditis resistant to penicillin, aminoglycosides, and vancomycin include administering vancomycin only if a patient is unable to tolerate penicillin or ampicillin, administering 6 weeks of vancomycin-gentamicin therapy for NVE and at least 6 weeks of therapy for PVE, and treating patients with E faecalis IE caused by strains that are intrinsically resistant to penicillin with a combination of vancomycin plus gentamicin.