what are the Recommendations for Management of Excessive Anticoagulation
and Serious Bleeding in Patients With Prosthetic Valves
Referenced studies that support the recommendations are
summarized in Online Data Supplement 37.?
For patients with bioprosthetic valves or annuloplasty rings who are receiving a direct oral anticoagulant and who require immediate reversal of anticoagulation because of uncontrollable bleeding, treatment with idarucizumab (for dabigatran) or andexanet alfa (for anti-Xa agents) is reasonable.