What is the effect of long-term intensive insulin treatment on the development of microvascular complications of diabetes mellitus?
Reichard P, Nilsson BY, Rosenqvist U. conducted a study which found that long-term intensive insulin treatment had a positive effect on the development of microvascular complications of diabetes mellitus. The study was published in the New England Journal of Medicine in 1993 and concluded that long-term intensive insulin treatment can reduce the risk of microvascular complications of diabetes mellitus.  