What is the evidence for the use of DOACs in patients with intracardiac thrombus?
The evidence for the use of DOACs in patients with intracardiac thrombus is limited largely to isolated case reports and small case series.529,540 546 It is also important to note that DOACs have not been studied specifically to prevent thromboembolism in patients with documented LV or left atrial thrombus. In addition, uncertainty about the optimal dosing of DOACs and the long-term safety remains.