What is the downgrade policy for the Clinical Evidence Summary in Table 106?
The downgrade policy for the Clinical Evidence Summary in Table 106 is as follows: Downgraded by 1 increment if the majority of the evidence was at high risk of bias, and downgraded by 2 increments if the majority of the evidence was at very high risk of bias. Downgraded by 1 increment if the confidence interval crossed 1 MID or by 2 increments if the confidence interval crossed both MIDs.