What is the purpose of the ALIAS trials?
The ALIAS (Albumin in Acute Ischemic Stroke) trials are a set of clinical trials designed to investigate the safety and efficacy of using external counterpulsation to augment cerebral blood flow in patients with acute ischemic stroke. The trials include the Counterpulsation to UpgradeForwardFlowinStroke (CUFFS) Trial, the NeuroThera Effectiveness and Safety Trial-2 (NEST2) and the NeuroThera Effectiveness and Safety Trial-3 (NEST3). Additionally, the HeadPoST (Head Positioning in Stroke Trial) was a cluster-randomized crossover trial of head positioning in acute stroke.