What is the relationship between glycated hemoglobin and stroke risk?
A systematic review and meta-analysis of studies by Mitsios et al. (2018) found that higher glycated hemoglobin levels were associated with an increased risk of ischemic stroke. This association was particularly pronounced in individuals with type 2 diabetes. Additionally, Folsom et al. (1999) found that fasting insulin levels, body fat distribution, and diabetes were associated with an increased risk of ischemic stroke. Finally, Selvin et al. (2010) found that glycated hemoglobin and diabetes were significantly associated with cardiovascular risk in nondiabetic adults. These findings suggest that elevated glycated hemoglobin levels may be associated with an increased risk of ischemic stroke.  