What is the recommended strategy for reversing Vitamin K Antagonists (VKA) in patients who suffer from ICH?
The recommended strategy for reversing Vitamin K Antagonists (VKA) in patients who suffer from ICH is rapid correction of the international normalized ratio (INR) with the use of fresh frozen plasma (FFP) and vitamin K. Vitamin K should be administered in a dose of 5 to 10 mg, usually via the intravenous route. Prothrombin complex concentrates (PCCs), the activated PCC FEIBA (factor VIII inhibitor bypassing activity), and recombinant activated factorVIIa (rFVIIa) have also emerged as potential therapies.