What is the association between hyperglycemia and poor outcome after ischemic brain injury?
Data obtained from consecutive patients with aSAH using historical controls to compare aggressive versus standard management of hyperglycemia suggest that effective glucose control after aSAH can significantly reduce the risk of poor outcome in these patients. Animal studies and human case series have demonstrated an association between elevated blood glucose concentration and poor outcome after ischemic brain injury. The mechanisms explaining such an association in human beings are unclear.