What effects has salicylic acid been found to have on endovascular infections caused by Staphylococcus aureus?
Salicylic acid has been found to attenuate virulence in endovascular infections caused by Staphylococcus aureus by targeting global regulatory pathways. It has also been found to reduce vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects. Additionally, it has been found to reduce valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients, as well as reduce mortality among patients with infective endocarditis. 