What is the recommendation for lowering systolic blood pressure from 120-129 mmHg to less than 120 mmHg?
The recommendation of lowering systolic blood pressure from 120-129 mmHg to less than 120 mmHg by pharmacologic or non-pharmacologic means is tentative. There have not been any randomized controlled trials in CKD targeting systolic blood pressure less than 120 mmHg that have included individuals with systolic blood pressure of 120-129 mmHg. However, observational data suggests that individuals with systolic blood pressure of 120-129 mmHg are at higher cardiovascular risk than those with systolic blood pressure less than 120 mmHg, so hypothetically, lowering the systolic blood pressure from 120-129 mmHg to less than 120 mmHg may be beneficial.