What is the impact of cerebral microbleeds on intracerebral hemorrhage and poor functional outcome in acute ischemic stroke patients treated with intravenous thrombolysis?
A systematic review and meta-analysis of several studies concluded that cerebral microbleeds may increase the risk of intracerebral hemorrhage and poor functional outcome in acute ischemic stroke patients treated with intravenous thrombolysis. Studies such as Charidimou et al. (2016) and Zand et al. (2017) found that those with a higher cerebral microbleed burden had an increased risk of symptomatic intracerebral hemorrhage after intravenous thrombolysis. Similarly, Wang et al. (2017) found that cerebral microbleeds were associated with a higher risk of intracerebral hemorrhage and poor functional outcome after intravenous thrombolysis. 