What data is used to support the recommendation for a BP target of 140/90 mm Hg for individuals without high risk?
Most recent BP guidelines have suggested a target BP of 140/90 mm Hg for all individuals who are not at high risk. This is based on several lines of evidence, including observational data suggesting that high BP is a risk factor for CVD,144 observational data suggesting that high BP is a risk factor for development and progression of RCTs of BP agents in the general population showing a benefit of a lower target BP,149,150 and RCTs in the general population demonstrating that the treatment of BP reduces CVD outcomes.151