What are the effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease?
The effects of citalopram and interpersonal psychotherapy on depression in patients with coronary artery disease were studied in the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy (CREATE) trial. The study found that citalopram and interpersonal psychotherapy both had significant effects on reducing depression in this population when compared to the control group. The study also found that the combination of citalopram and interpersonal psychotherapy was more effective than either intervention alone. Additionally, the study found that the effects of citalopram and interpersonal psychotherapy on depression were sustained over time.