What is the suggested statin treatment for adults aged 18-49 years with CKD but not treated with chronic dialysis or kidney transplantation?
The Work Group suggests statin treatment in people with one or more of the following: known coronary disease (myocardial infarction or coronary revascularization), diabetes mellitus, prior ischemic stroke, or an estimated 10-year incidence of coronary death or non-fatal myocardial infarction of 10% or greater. This decision is based on the high cardiovascular risk among people with CKD and eGFR categories G1-G2, the large body of evidence supporting the efficacy of statins in the general population, and the lack of an a priori reason why statins would be less effective in the presence of proteinuria.