What are the recommended INR values for patients with Non-valvular Atrial Fibrillation?
For patients with non-valvular Atrial Fibrillation, when Vitamin K Antagonists (VKAs) are used, it is recommended to have an International Normalized Ratio (INR) of 2.0 - 3.0, with attention to individual Targeted Therapeutic Range (TTR), ideally 70%. If TTR is sub-optimal (< 65-70%), additional measures like more regular INR tests, review of medication adherence, addressing other factors known to influence INR control and education/counseling can be taken to improve INR control or consider an Non-Vitamin K Antagonist Oral Anticoagulant (NOAC). When possible, experienced specialized anticoagulation clinics should be utilized for VKA and INR management.