What are the benefits of using Aldosterone antagonists for the progression of chronic kidney disease?
Aldosterone antagonists have been found to be beneficial for preventing the progression of chronic kidney disease. A systematic review and meta-analysis found that Aldosterone antagonists may reduce proteinuria and slow the rate of decline in estimated glomerular filtration rate (eGFR) in individuals with CKD. Other benefits of Aldosterone antagonists include improved blood pressure control, reduction in left ventricular hypertrophy, and improved lipid profile. Additionally, Aldosterone antagonists may reduce the risk of cardiovascular events and mortality in patients with CKD.  