What is the Peto odds ratio due to zero events in one trial?
The Peto odds ratio due to zero events in one trial is a statistical method used to estimate the effect of treatment on an outcome, where one or both of the groups have zero events. It is calculated as the ratio of the odds of the outcome in the treated group to the odds of the outcome in the control group and is commonly used in clinical trials where zero events occur in one of the treatment arms. In such cases, the Peto odds ratio is downgraded by one increment due to a high degree of heterogeneity, as indicated by an I2 statistic of 59%, which is not explained by subgroup analysis.