What are the benefits of assessing a patient's broader BP profile with out-of-office BP measurements?
Observational studies indicate that the diagnosis of high BP and BP control status differs for a high proportion of adults when BP is measured in the of ce versus outside the of ce, which can lead to detection of masked hypertension, masked uncontrolled hypertension, white-coat hypertension, and the white-coat effect. Further, observational studies indicate a stronger association of out-of-of ce BP measurements with CV and kidney outcomes than of ce BP measurements in the general population and CKD. Masked hypertension and masked uncontrolled hypertension are present among 9%-30% of adults without high BP based on of ce measurements and are associated with higher risk for CV disease and kidney outcomes compared with sustained normotension and sustained controlled hypertension, respectively. White-coat hypertension and the white-coat effect are present among 15%-30% of adults with high BP based on of ce measurements. In a recent meta-analysis, white-coat hypertension was associated with a reduced risk of CV events compared with sustained hypertension.