6/30/23, 11:51 PM Gynecomastia Pathway Feedback Search Clinical Topics Home Findings Gynecomastia Gynecomastia More common causes Liver cirrhosis Hyperthyroidism Lung cancer Hereditary hemochromatosis Noonan's syndrome POEMS syndrome 48/XXXY aneuploidy Less common causes Hypertrophic pulmonary osteo-arthropathy XX male syndrome Prolactinoma Orchidectomy Incomplete androgen insensitivity Testicular cancer Klinefelter syndrome 3-beta hydroxylase deficiency 49/XXXXY aneuploidy Leydig cell tumour https://web.pathway.md/findings/rectkF85ZBgiedoJW 1/2 6/30/23, 11:51 PM Gynecomastia Pathway Adrenal cortex tumor Uncommon causes Germinal cell aplasia Aromatase excess syndrome Aromatase deficiency Male gonadal dysgenesis 11 beta-hydroxylase deficiency https://web.pathway.md/findings/rectkF85ZBgiedoJW 2/2