What were the long-term effects of intensive glucose lowering on cardiovascular outcomes studied in the ACCORD trial?
The ACCORD trial studied the long-term effects of intensive glucose lowering on cardiovascular outcomes. The results of the study, reported by the ACCORD Study Group, Gerstein et al. (2011) showed that intensive glucose lowering did not reduce the risk of death from cardiovascular disease, stroke, or other causes, and it did increase the risk of severe hypoglycemia. The study concluded that intensive glucose lowering may not be beneficial for long-term cardiovascular outcomes in adults with type 2 diabetes at high risk for cardiovascular disease.  