What is the recommended monitoring for an MRA once the target, or maximum tolerated, dose is reached?
Once the target, or maximum tolerated, dose of an MRA is reached, monitor treatment monthly for 3 months and then at least every 6 months, and at any time the person becomes acutely unwell. Measure serum sodium and potassium and assess renal function before and after starting an MRA and after each dose increment. Measure blood pressure before and after each dose increment of MRA. Follow the recommendations on measuring blood pressure, including measurement in people with symptoms of postural hypotension, in the NICE guideline on hypertension in adults.