What are the clinical characteristics and outcomes of patients with and without diabetes in the Surgical Treatment for Ischemic Heart Failure (STICH) trial?
The Surgical Treatment for Ischemic Heart Failure (STICH) trial included 1,212 patients with ischemic heart failure and reduced left ventricular ejection fraction who were randomly assigned to receive coronary artery bypass grafting (CABG) plus medical therapy or medical therapy alone. The clinical characteristics and outcomes of patients with and without diabetes were compared in this trial. Results indicated that patients with diabetes had a higher prevalence of hypertension, prior myocardial infarction, prior stroke, and chronic kidney disease and lower ejection fraction compared to those without diabetes. Patients with diabetes also had higher mortality rates at one year follow-up compared to those without diabetes.