What is the recommended time frame for discontinuing clopidogrel before performing CABG?
It is recommended to discontinue clopidogrel for at least 24 hours before performing CABG to reduce major bleeding complications. For elective CABG, it is reasonable to delay the procedure for 5 days after discontinuing clopidogrel. Short-acting intravenous glycoprotein IIb/IIIa inhibitors (eptifibatide or tirofiban) should be discontinued for at least 2 to 4 hours before surgery and abciximab for at least 12 hours beforehand to limit blood loss and transfusions.