What methods did the committee use to assess the most cost-effective NT-proBNP threshold for diagnosing heart failure?
The committee used a cost-effectiveness analysis to determine which NT-proBNP threshold is the most cost effective for diagnosing heart failure in patients presenting with signs and symptoms of heart failure. The comparators included were NT-proBNP thresholds of 400pg/ml, 280pg/ml and 125pg/ml, and echocardiography for all.