What methods were used to search the scientific literature for the development of the CKD guideline?
For systematic reviews on treatment with different anti-hypertensive agents or to different BP targets, KDIGO searched for RCTs in MEDLINE, Cochrane Central Registry for trials, and Cochrane database of systematic reviews. Screening criteria are outlined in the Methods for Guideline Development chapter. The search was updated through January 2011 and supplemented by articles identified by Work Group members through February 2012. KDIGO also searched for pertinent existing guidelines and systematic reviews.