What is the role of coronary artery calcium score of zero and other negative risk markers for cardiovascular disease?
Studies have shown that a coronary artery calcium score of zero and other negative risk markers can be effective in reducing the risk of cardiovascular disease. For example, the Multi-Ethnic Study of Atherosclerosis (MESA) found that a positive family history for coronary heart disease in patients with a zero coronary artery calcium score could help reduce their risk of coronary heart disease. A meta-analysis of low-risk women also found that the identification of calcified coronary plaque was associated with the initiation and continuation of pharmacological and lifestyle preventive therapies. Furthermore, the American College of Cardiology and American Heart Association cholesterol guidelines suggest that coronary artery calcium testing may be cost-effective among statin candidates. Overall, a coronary artery calcium score of zero and other negative risk markers can be effective in reducing the risk of cardiovascular disease. 