What is the association between the TNF(- 308) promoter polymorphism and stroke risk in children with sickle cell anemia?
According to a study published in Stroke, there is an association between the TNF(- 308) promoter polymorphism and stroke risk in children with sickle cell anemia. The study found that the TNF(- 308) promoter polymorphism was associated with an increased risk of stroke in children with sickle cell anemia. In addition, the study also found that the presence of the TNF(- 308) promoter polymorphism was associated with an increased risk of silent cerebral infarcts. The findings from this study suggest that TNF(- 308) promoter polymorphism may be a useful marker for predicting stroke risk in children with sickle cell anemia. 