What criteria should be reviewed to determine patient eligibility for IV alteplase treatment for patients aged 80 or older within the 3-4.5 hour time window?
For patients aged 80 or older within the 3-4.5 hour time window, IV alteplase treatment is recommended without a history of both diabetes mellitus and prior stroke, an NIHSS score of 25, no use of oral anticoagulants, and without imaging evidence of ischemic injury involving more than one-third of the MCA territory.