What is the risk of developing cerebrovascular disease for women with a history of preeclampsia?
A 2008 systematic review and meta-analysis by McDonald et al181 noted that women with a history of preeclampsia/eclampsia had twice the risk of cerebrovascular disease (not further defined) as women without these disorders (RR, 2.03; 95% CI, 1.54 2.67). Another meta-analysis by Bellamy et al180 cohort studies and reported a cumulative OR of 1.81 for any stroke (OR, 1.81; 95% CI, 1.37 2.33) in women with a history of preeclampsia, whereas Brown et al184 noted an OR of 1.76 for cerebrovascular disease (95% CI, 1.43 2.21) for women with a history of pregnancies with preeclampsia.