What are the effects of clopidogrel in combination with aspirin when given before coronary artery bypass grafting?
The effects of clopidogrel in combination with aspirin when given before coronary artery bypass grafting have been studied and reported in a 2002 study published in the J Am Coll Cardiol. The results of this study revealed that clopidogrel in combination with aspirin reduces the risk of perioperative myocardial infarction, reduces the incidence of early and late thrombotic complications, and decreases the need for heparin during bypass surgery. However, it also increases the risk of bleeding complications and increases the amount of postoperative blood transfusions required.  