What are the common predisposing factors for statin-associated muscle symptoms (SAMS)?
The common predisposing factors for statin-associated muscle symptoms (SAMS) include age, female sex, low body mass index, high-risk medications (CYP3A4 inhibitors, OATP1B1 inhibitors), comorbidities (HIV, renal, liver, thyroid, preexisting myopathy), Asian ancestry, excess alcohol, high levels of physical activity, and trauma.