What are the results of the Medical Research Council/British Heart Foundation Heart Protection Study (HPS) on the use of statins in patients with diabetes mellitus?
The Medical Research Council/British Heart Foundation Heart Protection Study (HPS) found that the addition of a statin to existing treatments in high-risk patients with diabetes mellitus resulted in a 24% reduction (95% CI, 19 28) in the rate of major CVD events, a 22% reduction (95% CI, 13 30) in major vascular events (regardless of the presence of known coronary heart disease or cholesterol levels), and a 24% reduction (95% CI, 6 39; P=0.01) in strokes among 5963 diabetic individuals treated with the statin in addition to best medical care.