What are the effects of sevoflurane on myocardial function in coronary surgery patients?
Research has shown that sevoflurane can preserve myocardial function in coronary surgery patients, as compared to propofol. Studies have shown that sevoflurane can decrease PECAM-1 expression and improve long-term cardiovascular outcomes in coronary artery bypass graft surgery. Additionally, sevoflurane can also decrease biochemical markers for myocardial and renal dysfunction. Furthermore, sevoflurane may be associated with reduced in-hospital mortality after coronary artery bypass graft surgery. However, it is important to note that there may be diastolic dysfunction post-surgery, which is not influenced by the use of sevoflurane. 