What are the main elements of postthrombolysis care?
The main elements of postthrombolysis care are listed in Table 9. These include maintaining BP at <180/105 mmHg for at least the first 24 hours after IV alteplase treatment, as well as ENCHANTED (Enhanced Control of Hypertension and Thrombolysis Stroke Study) randomized 2196 alteplase-eligible patients with AIS and systolic BP (SBP) 150 mmHg to receive intensive target SBP of 130 to 140 mmHg within 1 hour versus guideline target SBP <180 mmHg; 1081 were in the intensive group, and 1115 were in the guideline group. Median time from stroke onset to randomization was 3.3 hours. Mean SBP in the intensive group was 144.3 mmHg, and mean SBP in the guideline group was 149.8 mmHg. Primary outcome mRS score at 90 days did not differ between the 2 groups.