6/28/23, 9:50 PM ECHOGUIDE Pathway Feedback Search Clinical Topics Home Studies ECHOGUIDE ECHOGUIDE Disease Traumatic hemorrhage Trial question Is ultrasound guidance superior to landmark guidance in patients requiring urgent femoral arterial and venous catheterization? Study design Single center Single blinded RCT Population Characteristics of study participants 25.0% female N = 136 75.0% male 136 patients (34 female, 102 male) Inclusion criteria: patients requiring both urgent arterial and venous femoral catheterization Key exclusion criteria: age < 18 years; contraindication to femoral access; clinical indication for only one catheter Interventions N=67 US-guided catheterization (identification of femoral artery and vein using ultrasound to guide catheter insertion) N=69 landmark-guided catheterization (using anatomic landmarks by palpating the femoral pulse to guide catheter insertion) Primary outcome Occurrence of 1 mechanical complication 58.0 % 58 https://web.pathway.md/studies/recwnc69yCfjX00be 1/2 6/28/23, 9:50 PM ECHOGUIDE Pathway 43.5 % 33 29.0 % Significant decrease 14.5 % NNT = 4 0.0 % Ultrasound-guided catheterization Landmark-guided catheterization Significant decrease in occurrence of 1 mechanical complication (33% vs. 58%; OR 0.35, 95% CI 0.18 to 0.71) Secondary outcomes Significant increase in successful catheterization (96% vs. 74%; OR 7.5, 95% CI 2.1 to 27) No significant difference in cannulation time (103 seconds vs. 121 seconds; AD -18 seconds, 95% CI -39.46 to 3.46) Significant decrease in the number of punctures (2 vs. 3; AD -1, 95% CI -1.84 to -0.16) Safety outcomes No significant differences in bleeding, late hematomas. Significant differences in immediate complications (27% vs. 51%), late complications (10% vs. 23%). Conclusion In patients requiring both urgent arterial and venous femoral catheterization, US-guided catheterization was superior to landmark-guided catheterization with respect to occurrence of 1 mechanical complication. Reference Stephen Lazaar, Am lie Mazaud, Claire Delsuc et al. Ultrasound guidance for urgent arterial and venous catheterisation: randomised controlled study. Br J Anaesth. 2021 Dec;127(6):871-878. Open reference URL https://web.pathway.md/studies/recwnc69yCfjX00be 2/2