What is the proposed functional EHRA categorization in relation to the type of oral anticoagulation (OAC) use in patients with AF?
The proposed functional EHRA categorization in relation to the type of oral anticoagulation (OAC) use in patients with AF is a classification system that is designed to easily evolve or be updated when there are new results. This classification system is outlined in Table 11 and includes Type 1, where mechanical heart valves should only be prescribed VKAs; Type 2, where bioprosthetic valves are included in the ARISTOTLE (apixaban), the Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation Thrombolysis In Myocardial Infarction study 48 (ENGAGE AF-TIMI 48) (edoxaban), and the relative efficacy and safety of NOACs compared with warfarin is consistent; and Type 3, where transcatheter mitral valve interventions are emerging as a possible option but more data are awaited, especially in relation to OAC use.