What is the prognostic value of fasting versus non-fasting low-density lipoprotein cholesterol levels on long-term mortality?
According to a study by Doran et al. (2014) published in Circulation, the prognostic value of fasting versus non-fasting low-density lipoprotein cholesterol levels on long-term mortality is significant, with fasting LDL cholesterol levels being associated with a lower risk of mortality than non-fasting LDL cholesterol levels. This finding was further supported by a meta-analysis conducted by Sniderman et al. (2011), which found that LDL cholesterol, non-HDL cholesterol, and apolipoprotein B were all significantly associated with an increased risk of cardiovascular disease, regardless of whether they were measured in a fasting or non-fasting state.  