What is the recommended regimen for administration of magnesium sulfate for women with eclampsia?
The Collaborative Eclampsia Trial regimen for administration of magnesium sulfate for women with eclampsia is a loading dose of 4 g given intravenously over 5 to 15 minutes, followed by an infusion of 1 g/hour maintained for 24 hours. If the woman has had an eclamptic fit, the infusion should be continued for 24 hours after the last fit. Recurrent fits should be treated with a further dose of 2 to 4 g given.