Is it reasonable to treat people with high BP, CKD, and no albuminuria, with or without diabetes, with RASi (ACEi or ARB)?
Yes, it may be reasonable to treat people with high BP, CKD, and no albuminuria, with or without diabetes, with RASi (ACEi or ARB). While existing evidence does not demonstrate clear clinical benefits of RASi for CKD progression, some patients may put a high value on the CV protection from RASi and may be willing to tolerate the potential harms, particularly those with higher GFR and a relatively low risk of harm.