What is the cost-effectiveness of diagnosing heart failure?
The disaggregated costs and QALYs from the probabilistic base case analysis suggest that echo all has the highest cost-effectiveness, with a mean cost of £5,496 per QALY gained. Multiple sensitivity analyses were undertaken on the base case analysis, and none of these changed the optimal strategy. In addition, two scenario analyses using alternative diagnostic accuracy study data from Verdu et al. 2012 and Zaphiriou et al. 2005 were undertaken, however the results did not change the optimal strategy.