What studies have been conducted to evaluate the discrimination of risk stratification scores in patients with CKD?
A recent analysis of 7 risk stratification scores showed that all had substantially poorer discrimination in CKD patients than those without CKD (c-statistics, 0.50-59 vs 0.69- 0.70, respectively), and inclusion of CKD stage did not improve calibration or discrimination.430 One study from Taiwan showed that the CHA2DS2-VASc score could adequately risk stratify for ischemic stroke among a hemodialysis population (c-index, 0.682; superior to the CHA2DS2-VASc in a general population).