What databases were searched for evidence-based studies on stroke?
The Internet Stroke Center/Clinical Trials Registry (http://www.strokecenter.org/trials/) and National Guideline Clearinghouse (http://guideline.gov/) were searched. Articles included were limited to those that were randomized, controlled trials; systematic reviews; meta-analyses; and in some cases, cohort studies. The database searches were also limited to articles with English-language citations, with human subjects, and published between January 1, 2009, and varying end dates (between October 2, 2012, and December 6, 2012).