What are the factors that could be operative in causing an increased infection rate among younger patients?
Klug et al105 demonstrated that young patients with or without congenital defects have a greater prevalence of PPM lead infections than older ( 40 years of age) individuals. They speculated that several factors could be operative in causing an increased infection rate among younger patients, including a higher rate of reinterventions at the generator site, placement of a relatively larger device based on a higher ratio between the volume of the generator and body size, and the likelihood of local trauma to the generator site in younger, Baddour et al Cardiovascular Device Infections 469 more active individuals.