What are the benefits of using NOACs compared to VKAs for stroke prevention in AF?
NOACs have several benefits compared to VKAs for stroke prevention in AF, including a rapid onset/offset of action, absence of an effect of dietary vitamin K intake on their activity, and fewer drug interactions. Additionally, the predictable anticoagulant effects of the NOACs enable their administration in fixed doses without the need for routine coagulation monitoring, thereby simplifying therapy.