What is the role of coronary microvascular disease and endothelial dysfunction in the pathophysiology of NSTE-ACS in patients with nonobstructive CAD?
It has been suggested that coronary microvascular disease and endothelial dysfunction play a role in the pathophysiology of NSTE-ACS in patients with nonobstructive CAD. This is supported by research showing that patients with NSTE-ACS and nonobstructive CAD have higher levels of biomarkers related to endothelial dysfunction and coronary microvascular disease than those without nonobstructive CAD. Additionally, it has been found that patients with NSTE-ACS and nonobstructive CAD have worse outcomes than those without nonobstructive CAD.