what are the Recommendations for Management of Excessive Anticoagulation
and Serious Bleeding in Patients With Prosthetic Valves
Referenced studies that support the recommendations are
summarized in Online Data Supplement 37.?
F or patients with a mechanical prosthetic valve and supratherapeutic INR (>5.0) who are not actively bleeding, the benefit of individualized treatment with oral vitamin K, in addition to temporary withdrawal of the VKA, is uncertain.