What is the SAMe-TT2R2 score and what is its purpose?
The SAMe-TT2R2 score is a predictive tool used to forecast good or poor anticoagulation control in patients with atrial fibrillation (AF). It has been assessed in 15 exclusively AF cohorts, reporting its predictive ability to forecast good or poor anticoagulation control, with c-statistics ranging from 0.54. The score has been tested in some VTE populations, where it can identify patients likely to achieve a good TTR. It can also be used to aid decision-making in health-care systems where the patient has to have a period on VKA and their TTR determined, before a decision to use an NOAC is approved. Patients with score 0-2 are likely to achieve a good TTR. 