What are the potential risks associated with LMWH and UFH preparations?
Both UFH and LMWH preparations have the potential to produce osteopenia. UFH has been associated with a greater risk of bone mineral density loss than LMWH. Rarely, skin necrosis can occur at sites of injection with LMWH and urticarial skin reactions can occur with both UFH and LMWH. HIT should be suspected in cases of skin necrosis.