What is the association between Lp(a) levels and ischemic stroke in the ARIC study?
In the ARIC study, the incidence of ischemic stroke was significantly increased in individuals with higher Lp(a) levels after adjustment for age, sex, and CVD risk factors, and this association was stronger in blacks than in whites. Compared with those with Lp(a) <10 mg/dL, the incidence of ischemic stroke was 2.12-fold greater (RR, 2.12; 95% CI, 1.48 3.03) in blacks with Lp(a) >30 mg/dL.