What are the benefits of long-term oral dipyridamole treatment on coronary microcirculatory function in patients with chronic stable angina?
A substudy of the Persantine in Stable Angina (PISA) study found that long-term oral dipyridamole treatment can improve coronary microcirculatory function in patients with chronic stable angina. This was seen in terms of improved myocardial perfusion, increased coronary flow reserve, and increased exercise duration. These beneficial effects were seen at doses of up to 200mg daily, with no significant side effects