What are the main laboratory tests used to monitor anticoagulant therapy?
The main laboratory tests used to monitor anticoagulant therapy include prothrombin time (PT) and activated partial thromboplastin time (aPTT). These tests measure the activity of the coagulation factors and are used to determine if the anticoagulation therapy is having the desired effect. Other tests, such as the thrombin clotting time (TCT) and euglobulin lysis time (ELT), also measure the activity of these coagulation factors and may be used to monitor anticoagulant therapy. Additionally, laboratory tests such as serum creatinine and hematocrit can be used to monitor renal function and monitor for potential adverse effects of anticoagulants. 