What are the implications of NT-proBNP threshold of 400pg/ml for diagnosis of chronic heart failure?
The NT-proBNP threshold of 400pg/ml is the most cost effective strategy at a threshold of 20,000 per QALY gained (ICER: 5,496 compared to echo all) with a probability of 77% of being the most cost effective at the 20,000 threshold. This result is robust to multiple sensitivity analyses varying key input parameters and structural assumptions. This analysis was assessed as directly applicable with potentially serious Chronic Heart Failure Diagnosing heart failure NICE 2018. All rights reserved. Subject to Notice of rights. ISBN: 978-1-4731-3093-7 limitations.