What is the evidence reported in the study comparing CABG (plus medical management) with medical management alone?
The evidence for the outcomes from one study (n=1212) comparing CABG (plus medical management) with medical management alone ranged from moderate to very low. This was due to a risk of bias and imprecision as a result of wide confidence intervals around the effect estimate. A single outcome (NYHA class I) was downgraded due to indirectness of the outcome. The outcome reported was the number of people in NYHA class I at the specified follow-up point of 4.7 years rather than the protocol outcome which was improvement in NYHA class. QoL as measured by the EQ-5D, EQ-5D VAS and KCCQ; all-cause hospitalisation and the need for subsequent procedures (CABG and PCI) showed clinically important benefit from CABG (plus medical management).