What is the potential for triglyceride elevation with bile acid sequestrants? 
The potential for triglyceride elevation with bile acid sequestrants is a potential issue that must be taken into account when considering the use of these medications. Bile acid sequestrants can increase levels of triglycerides in some individuals, however, this risk must be weighed against the potential benefit of adding this medication to existing cholesterol-lowering therapy, such as a statin. Additionally, the potential for drug interactions, the absence of well-tolerated generic formulations, the need for twice-daily dosing, and the high pill burden must be considered when deciding if bile acid sequestrants are an appropriate treatment option.