What is the best anticoagulation regimen for the prevention of cardioembolism from AF in patients with ischemic stroke or TIA and cancer?
In patients with ischemic stroke or TIA in the setting of AF and cancer, it is reasonable to consider anticoagulation with DOACs in preference to warfarin for stroke prevention. Low-molecular-weight heparin agents are commonly used empirically when a hypercoagulable state is suspected, but the benefit is unclear, particularly in this patient population with a high tendency for hemorrhage.651