What is the effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization?
A meta-analysis of 11 randomised controlled trials by Troughton et al (2014) found that B-type natriuretic peptide-guided treatment of chronic heart failure had a significant effect on total mortality and hospitalization, with a reduction of 22% in all-cause mortality and a reduction of 26% in hospitalization for heart failure.