A relationship is considered to be significant if (a) the person receives $10000 or more during any 12-month period, or 5% or more of the person s gross income; or (b) the person owns 5% or more of the voting stock or share of the entity, or owns $10000 or more of the fair market value of the entity. A relationship is considered to be modest if it is less than significant under the preceding definition. *Modest. Significant. Disclosures ICH outcome have resulted from improved hospital care. Improvements in hospital care tend to be incremental rather than revolutionary but can sum to substantial benefits to patients and remain a key part of future ICH research. Acute ICH treatment, like acute ischemic stroke treatment, is fundamentally limited in its ability to reduce stroke-related disability; for this reason, it is improved ICH prevention and recovery that has the greatest potential for reducing overall disease burden. In the area of ICH prevention, BP control can be considered as established treatment.273,328 There remains no disease-modifying treatment for prevention of CAA-related ICH; however, this is a major goal for ongoing and future tri- als. Another important question to be addressed is the possible role of the newer direct OACs in patients at increased ICH risk and the identification of the subgroup that might derive the greatest benefit from the reduced tendency of these agents to trigger intracranial bleeding.72,73,304 Finally, there are no spe- cific treatments or therapies established for enhancing post- ICH recovery, which highlights a tremendous opportunity for improving outcome from this devastating form of stroke. Hemphill et al Management of Spontaneous ICH 2051 References 1. Zahuranec DB, Gonzales NR, Brown DL, Lisabeth LD, Longwell PJ, Eden SV, Smith MA, Garcia NM, Hoff JT, Morgenstern LB. Presentation of intracerebral haemorrhage in a community. 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Diabetologia. 2010;53:429 434. doi: 10.1007/s00125-009-1617-z. Reviewer Disclosures Reviewer Employment Research Grant Other Research Support Speakers Bureau/Honoraria Expert Witness Ownership Interest Consultant/ Advisory Board Other Sepideh Amin-Hanjani University of Illinois at Chicago NIH/NINDS (Site PI on MISTIE 3 trial)* None None None None None None Charlotte Cordonnier Lille University Hospital (France) None None None None None None None Matthew L. Flaherty University of Cincinnati Academic Health Center NINDS (Coinvestigator on NINDS-funded grants NS030678, (Principal Investigator, NINDS 2P50NS044283, STOP-IT Study ) Novo Nordisk (Principal Investigator of NINDS-funded STOP-IT Study, study drug supplied by Novo Nordisk)* CSL Behring* None Sense Diagnostics, LLC CSL Behring* None Eric E. Smith University of Calgary None None None None None None None This table represents the relationships of reviewers that may be perceived as actual or reasonably perceived conflicts of interest as reported on the Disclosure Questionnaire, which all reviewers are required to complete and submit. A relationship is considered to be significant if (a) the person receives $10000 or more during any 12-month period, or 5% or more of the person s gross income; or (b) the person owns 5% or more of the voting stock or share of the entity, or owns $10000 or more of the fair market value of the entity. A relationship is considered to be modest if it is less than significant under the preceding definition. *Modest. Significant. 17. B jot Y, Aboa-Eboul C, Hervieu M, Jacquin A, Osseby GV, Rouaud O, Giroud M. The deleterious effect of admission hyperglycemia on sur- vival and functional outcome in patients with intracerebral hemorrhage. Stroke. 2012;43:243 245. doi: 10.1161/STROKEAHA.111.632950. 18. 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