Did the VALISH study demonstrate any differences in outcomes or adverse events between the strict-control and moderate-control groups?
No, the study did not demonstrate any differences in outcomes or adverse events between the strict-control group (systolic BP goal o140 mm Hg, achieved mean systolic BP was 136.6 mm Hg) and the moderate-control group (systolic BP goal 140 150 mm Hg, achieved mean systolic BP was 142.0 mm Hg) after a median follow-up period of 3.07. No difference was seen between the two groups in terms of adverse event rates (18.2% with strict control and 17.9% with mild control, P 0.851).