What is the effectiveness of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction?
A meta-analysis of randomized trials published in 2004 found that glycoprotein IIb/IIIa inhibitors are effective for primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction. The analysis showed that early administration of glycoprotein IIb/IIIa inhibitors was associated with improved angiographic success rate, less ventricular fibrillation, and lower mortality rates compared to late administration. Furthermore, the study found that the effectiveness of glycoprotein IIb/IIIa inhibitors was not affected by the type of stent used.  