What is the risk benefit ratio of prophylactic aspirin for adults under the age of 40 and over the age of 70?
For adults under the age of 40, there is insufficient evidence to judge the risk benefit ratio of routine aspirin for the primary prevention of ASCVD. For adults over the age of 70, prophylactic aspirin in primary-prevention is potentially harmful and, given the higher risk of bleeding in this age group, difficult to justify for routine use.