What is the recommendation for the prevention of a first stroke in people with chronic kidney disease?
Aspirin may be considered for the prevention of a first stroke in people with chronic kidney disease (ie, estimated glomerular filtration rate <45 mL min 1 ) (Class IIa; Level of Evidence C). This recommendation does not apply to severe kidney disease (stage 4 or 5; estimated glomerular filtration rate <30 mL min 1 ). It may be beneficial to also use a cardiovascular risk calculator to assess risk and inform decision-making.