What is the current recommendation for the use of prophylactic aspirin? 
The current recommendation for the use of prophylactic aspirin is a Class IIb recommendation for adults 40 to 70 years of age. Low-dose aspirin of up to 100 mg daily is suggested, as meta-analyses suggest that the ASCVD risk benefit for low-dose aspirin is equivalent to that for high-dose aspirin, but the bleeding risk is higher with high-dose aspirin. Future research is suggested on the personalization of prophylactic aspirin dose according to patient-specific factors.