What are the effects of intensive blood pressure control in type 2 diabetes mellitus?
In type 2 diabetes mellitus, intensive blood pressure control has been shown to reduce the risk of major cardiovascular events, stroke, and death. In the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, intensive blood pressure control was associated with a 16% reduction in the primary outcome of nonfatal myocardial infarction or stroke, and a 17% reduction in all-cause mortality. The Systolic Blood Pressure Intervention Trial (SPRINT) also demonstrated that intensive blood pressure control reduced the risk of major cardiovascular events by 25%, stroke by 35%, and death from any cause by 27% compared to standard blood pressure control. Overall, intensive blood pressure control has been shown to reduce the risk of cardiovascular events, stroke, and death in type 2 diabetes mellitus. 