What is the benefit of statin use in persons with albuminuria and preserved eGFR?
Trials show absolute benefit from statin use, and this benefit is consistent across eGFR stages. However, the RRR per LDL-C lowering may be lower with more advanced CKD. Albuminuria is independently associated with CVD risk. However, the one trial done for primary prevention in persons with albuminuria and preserved eGFR had too few events to be conclusive.