What is the recommended maintenance dose of aspirin to be used with ticagrelor?
The recommended maintenance dose of aspirin to be used with ticagrelor is 81 mg daily, according to the 2014 AHA/ACC NSTE-ACS Guideline. It is recommended to administer clopidogrel with aspirin for patients with NSTE-ACS, with an initial loading dose of 300 mg to 600 mg. A 600-mg loading dose results in a greater, more rapid, and more reliable platelet inhibition compared with a 300-mg loading dose.301