What is the most sensitive biomarker for Non-ST Elevation Acute Coronary Syndrome?
Cardiac troponins are the most sensitive and specific biomarkers for Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS). They rise within a few hours of symptom onset and typically remain elevated for several days (but may remain elevated for up to 2 weeks with a large infarction). A negative cardiac troponin obtained with more sensitive cardiac troponin assays on admission confers a >95% negative predictive value for MI compared with high-sensitivity assays that confer a negative predictive value 99%.