What is the ef cacy and safety of anticoagulant treatment in acute cardioembolic stroke?
The efficacy and safety of anticoagulant treatment in acute cardioembolic stroke is supported by a meta-analysis of randomized controlled trials, as reported in Paciaroni et al. (2007). The meta-analysis of randomized controlled trials showed that anticoagulants were more effective than placebo in reducing the risk of recurrent embolic stroke in patients with acute cardioembolic stroke and atrial fibrillation. Furthermore, anticoagulants were found to be safe, with no significant increase in the risk of bleeding or mortality compared to placebo.  