what are the Recommendations for Atrial Septal Defect
Referenced studies that support recommendations are summarized
in Online Data Supplement 26 and the systematic review
report.S4.1.1-1?
A dults with primum ASD, sinus venosus defect or coronary sinus defect causing impaired functional capacity, right atrial and/ or RV enlargement and net left-to-right shunt sufficiently large to cause physiological sequelae (eg, Qp:Qs ?1.5:1) without cyanosis at rest or during exercise, should be surgically repaired unless precluded by comorbidities, provided that systolic PA pressure is less than 50% of systemic pressure and pulmonary vascular resistance is less than one third of the systemic vascular resistance.S