What is the effect of sodium restriction on albuminuria?
Several studies have shown that dietary sodium restriction can reduce albuminuria in nondiabetic patients with hypertension treated with olmesartan. In a cluster randomized trial, dietary sodium reduction was found to reduce albuminuria (Jardine et al., 2019). A randomized crossover trial of dietary sodium restriction in stage 3-4 CKD also found that sodium restriction decreased proteinuria and blood pressure (Saran et al., 2017). Additionally, a randomized controlled trial of self-management support found that sodium restriction in patients with CKD led to a reduction in albuminuria (Meuleman et al., 2017).