What is the recommended treatment for patients with stroke and diagnosed neurosyphilis?
Intense treatment with penicillin G is mandated for patients with stroke and diagnosed neurosyphilis. Testing for HIV is also indicated in these patients, as there is a relatively high coexistence (5%-16%) of both sexually transmitted diseases. In some instances, there may be coexisting comorbidities that may also predispose to stroke such as large artery atherosclerosis or AF; in such cases, treating neurosyphilis is still indicated in addition to the confounding competing risk of stroke.