What is the optimal antiplatelet and anticoagulant therapy in patients with oral anticoagulation and coronary stenting?
The WOEST (What is the Optimal Antiplatelet and Anticoagulant Therapy in Patients With Oral Anticoagulation and Coronary Stenting) study found that in patients taking oral coagulants who required PCI, use of clopidogrel without aspirin was associated with a significant reduction in bleeding complications and no increase in thrombotic events. However, practice should not be changed on the basis of this limited study alone.