What are the effects of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery?
The impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery was studied in a multicenter analysis by Berger et al. (2008). Results showed that clopidogrel was associated with an increased risk of postoperative bleeding and transfusions, as well as a higher rate of reoperation for bleeding, compared to ticagrelor or aspirin (Held et al., 2010; Hongo et al., 2002; Firanescu et al., 2009; Herman et al., 2010; Mehta et al., 2009; Bizzarri et al., 2001; Dyke et al., 2000; Lincoff et al., 2000). 