What is the prognostic value of galectin-3 in patients with chronic heart failure?
The prognostic value of galectin-3 in patients with chronic heart failure has been studied in several studies. The results of a study published in Clinical Res Cardiol in 2010 found that galectin-3 levels were significantly associated with mortality in patients with chronic heart failure. A 2011 study published in the American Journal of Cardiology found that plasma galectin-3 levels were associated with an increased risk of renal insufficiency and mortality in systolic heart failure. Additionally, a 2016 study published in the Journal of the American College of Cardiology found that baseline and changes in circulating soluble ST2 levels were associated with an increased risk of mortality in acute decompensated heart failure. Furthermore, a 2012 study published in Biomarkers found that galectin-3 complemented BNP in risk stratification in acute heart failure. Lastly, a 2013 study published in the International Journal of Cardiology found that ST2 and other biomarkers were associated with increased mortality in acutely decompensated heart failure.  