What is the definition of ESUS?
ESUS has been defined as ischemic stroke detected by CT or MRI that, after a standardized and adequate diagnostic pathway including brain imaging, echocardiography, cardiac rhythm monitoring for at least 24 h, and imaging of the intracranial and extracranial arteries supplying the affected brain area: is not lacunar (subcortical, < 15 mm diameter); where there is absence of extracranial or intracranial atherosclerosis causing $ 50% luminal stenosis in the arteries supplying the area of ischemia; no major-risk cardioembolic source of embolism (permanent or paroxysmal AF, sustained atrial utter, intra-cardiac thrombus, prosthetic cardiac valve, atrial myxoma or other cardiac tumours, mitral stenosis, recent [< 4 weeks] MI, left ventricular ejection fraction < 30%, valvular vegetations, or infective endocarditis); and no other specific cause of stroke identified (eg, arteritis, dissection, migraine/vasospasm).