What is the recommended dose of gentamicin when used for synergy in children?
When gentamicin is used for synergy, it is reasonable to give a dose of 3 to 6 mg/kg per day (divided as an every 8-hour regimen) in children, adjusted for a target peak blood concentration of 3 to 4 g/mL and a trough of <1 g/mL (Class IIa; Level of Evidence B).