What was the purpose of the study, Intensive versus moderate lipid lowering with statins after acute coronary syndromes?
The purpose of the study was to investigate the effects of intensive versus moderate lipid lowering with statins after acute coronary syndromes. This was done through a meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy, as well as through the Helsinki Heart Study, which was a primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. The study also investigated the effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus, and the safety and efficacy of atorvastatin-induced very low-density lipoprotein cholesterol levels in patients with coronary heart disease. Finally, the study looked at the effects of insulin resistance and low HDL cholesterol on cardiovascular events. 