What is the purpose of the Tenecteplase in Stroke Investigators study?
The Tenecteplase in Stroke Investigators study was a Phase IIB/III trial of tenecteplase in acute ischemic stroke, designed to evaluate the efficacy and safety of the drug in comparison to alteplase. It was a randomized clinical trial that was prematurely terminated, with results published in Stroke (2010). The study was conducted by Haley EC Jr, Thompson JL, Grotta JC, Lyden PD, Hemmen TG, Brown DL, Fanale C, Libman R, Kwiatkowski TG, Llinas RH, and other members of the Tenecteplase in Stroke Investigators.