What is the recommendation of the Work Group regarding the BP target for patients with diabetes and CKD?
The Work Group did not consider the evidence from the HOT220 trials strong enough to justify a recommendation to lower the target diastolic BP to below 80 mm Hg. The Work Group analyzed the evidence base for the existing guidelines carefully to ensure that the apparent departure from accepted wisdom was justified. Few existing guidelines specify how patients with normoalbuminuric CKD and diabetes should be treated with BP-lowering drugs, with the majority advising a BP target of no lower than 130/80 mmHg for all patients with diabetes, irrespective of GFR or albuminuria.