What techniques have been used to mitigate the occurrence of SIRS after CPB?
Techniques used to mitigate the occurrence of SIRS after CPB include preoperative intravenous methylprednisolone, use of intravenous immunoglobulin G, use of CPB circuits (including oxygenators) coated with materials known to reduce complement and leukocyte activation, use of CPB tubing that is covalently bonded to heparin, use of CPB tubing coated with polyethylene oxide polymer, Poly (2-methoxyethylacrylate), leukocyte depletion via specialized filters in the CPB circuits, and closed mini-circuits for CPB. 