What are the risks associated with warfarin after an acute MI?
A meta-analysis of 24542 patients in 10 randomized trials that evaluated the efficacy of warfarin after acute MI found a stroke incidence over 5 years of 2.4%. In this meta-analysis, warfarin decreased the risk of stroke (OR, 0.75; 95% CI, 0.63 0.89) but increased the risk of major bleeding.