What is the definition of cardiac aetiology based on LVEF < 40%?
Aetiology of heart failure based on LVEF < 40% is defined as idiopathic dilated cardiomyopathy when no known cause of cardiomyopathy could be found, ischaemia when typical history of coronary artery disease, history of myocardial infarction, or presence of significant (70%) coronary artery stenoses had been hypertension when history of established hypertension or antihypertensive therapy was present, and valvular heart disease; people with primary valvular disease (that had to be surgically repaired for at least 6 months) and people with nonischaemic dilated cardiomyopathy associated with a significant mitral valve insufficiency clinical stability, defined as the absence of any episode of heart failure decompensation during the 6 week period before entry into the trial and the absence of major modification of heart failure therapy in the previous 3 weeks.