What drugs affect parts of the renin-angiotensin pathway and are effective in the treatment of heart failure with reduced ejection fraction (HFREF)?
A number of drugs affecting parts of the renin-angiotensin pathway have been developed and shown to be effective in the treatment of heart failure with reduced ejection fraction (HFREF). These drugs include angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and mineralocorticoid receptor antagonists such as spironolactone and eplerenone.