What were the findings of the Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia?
The findings of the Controlled Trial of Transfusions for Silent Cerebral Infarcts in Sickle Cell Anemia, as reported in the New England Journal of Medicine in 2014, found that transfusions were effective in reducing the risk of overt stroke in children with sickle cell anemia who had experienced silent cerebral infarcts. The trial included a total of 841 participants and found that those who received transfusions were 63% less likely to experience an overt stroke compared to those who did not receive transfusions.