7/1/23, 12:38 AM Hyperpigmentation Pathway Feedback Search Clinical Topics Home Findings Hyperpigmentation Hyperpigmentation More common causes Varicose veins Acanthosis nigricans Kwashiorkor Chronic kidney disease Hypothyroidism Nevus of Ota Hereditary hemochromatosis Rosacea Malassezia furfur Onchocerciasis Freckles X-linked dominant chondrodysplasia punctata 2 Hematoma Cutaneous T-cell lymphoma Melanoma Alkaptonuria Less common causes Fanconi's anemia Chloasma https://web.pathway.md/findings/recc72HHfBeu61lyT 1/4 7/1/23, 12:38 AM Hyperpigmentation Pathway Addison's disease Superficial thrombophlebitis Lichen simplex chronicus Spitz nevus Caf au lait spots Epidermal nevus Whipple's disease Blue nevus Jaundice Primary biliary cholangitis Hemosiderin deposition Variegate porphyria Dermatofibroma Poikiloderma of Civatte Porphyria cutanea tarda type 1 Incontinentia pigmenti Systemic sclerosis Gaucher's disease Hidrotic ectodermal dysplasia Visceral leishmaniasis Scleredema Poikiloderma Slate grey skin Congenital erythropoeitic porphyria Systemic mastocytosis Nevus spilus Dyschromatosis universalis hereditaria https://web.pathway.md/findings/recc72HHfBeu61lyT 2/4 7/1/23, 12:38 AM Hyperpigmentation Pathway Silver poisoning Basal cell papilloma X-linked dyskeratosis congenita Uncommon causes Phytophotodermatitis Tinea nigra Dermatosis papulosa nigra Autoimmune adrenalitis Hereditary sensory and autonomic neuropathy type 3 Neurocutaneous melanosis Lentiginosis Riehl melanosis Erythromelanosis follicularis faciei et colli Mongolian blue spots Pigmented naevus Atrophoderma of Pasini and Pierini Erythrokeratodermia variabilis et progressiva Hypercarotinemia Pigmented hairy epidermal nevus Photocontact dermatitis UROD-related porphyria cutanea tarda Erythema dyschromicum perstans Reticulate acropigmentation of Dohi Schimke immunoosseous dysplasia Dermatopathia pigmentosa reticularis Autosomal dominant dyskeratosis congenita https://web.pathway.md/findings/recc72HHfBeu61lyT 3/4 7/1/23, 12:38 AM Hyperpigmentation Pathway Carney complex Familial carotenemia Type 2 microcephalic osteodysplastic primordial dwarfism https://web.pathway.md/findings/recc72HHfBeu61lyT 4/4