What are the current treatments for orolingual angioedema associated with alteplase therapy of acute stroke?
The current treatments for orolingual angioedema associated with alteplase therapy of acute stroke include antihistamines, corticosteroids, and epinephrine. In cases where the angioedema is severe, the use of intravenous immunoglobulin, plasmapheresis, or tranexamic acid may be recommended. In addition, discontinuation of antithrombotic medications or other medications that may be contributing to the angioedema should be considered. In some cases, supportive care with airway management may also be indicated.  