Guideline sources The following summarized guidelines for the management of tension-type headache are prepared by our editorial team based on guidelines from the European Federation of Neurological Societies (EFNS 2010). 1 Guidelines 1. Medical management Acute therapy: Offer the following agents for acute therapy in patients with tension-type headache: ibuprofen 200-800 mg A ketoprofen 25 mg A acetylsalicylic acid 500-1,000 mg A naproxen 375-550 mg A diclofenac 12.5-100 mg A acetaminophen PO 1,000 mg A caffeine combination 65-200 mg. B Show 3 more 2. Nonpharmacologic interventions https://web.pathway.md/diseases/recaiRhRnJezEdy0D 1/2 6/24/23, 4:05 PM Tension-type headache Pathway Non-pharmacological therapies: Consider offering the following nonpharmacological treatments in patients with tension-type headache: EMG biofeedback B CBT C relaxation training C physical therapy C acupuncture. C 3. Preventative measures Prophylactic therapy: Offer the following agents for prophylactic therapy in patients with tension-type headache: Situation Guidance Amitriptyline 30-75 mg A First-line therapy Mirtazapine 30 mg Second-line therapy Venlafaxine 150 mg B Clomipramine 75-150 mg Third-line therapy Maprotiline 75 mg Mianserin 30-60 mg. B Offer the following agents for prophylactic therapy in patients with chronic tension-type headache: first-line therapy: amitriptyline second-line therapy: mirtazapine, venlafaxine. E References 1. L Bendtsen, S Evers, M Linde et al. EFNS guideline on the treatment of tension-type headache Report of an EFNS task force. Eur J Neurol. 2010 Nov;17 11 1318 25. Open https://web.pathway.md/diseases/recaiRhRnJezEdy0D 2/2