What factors are taken into account when determining the strength of a recommendation?
The factors taken into account when determining the strength of a recommendation are the balance between desirable and undesirable effects, the quality of evidence, values and preferences, and costs (resource allocation). The larger the difference between the desirable and undesirable effects, the higher the quality of evidence, and the fewer resources consumed, the more likely a strong recommendation is warranted. Conversely, the narrower the gradient, the lower the quality of evidence, and the higher the costs of an intervention, the more likely a weak recommendation is warranted.