What is the purpose of the VISSIT trial?
The purpose of the VISSIT trial was to evaluate the effect of a balloon-expandable intracranial stent compared to medical therapy on the risk of stroke in patients with symptomatic intracranial stenosis. The trial was a randomized, open-label, multicenter clinical trial conducted at multiple sites across the US. The primary outcome measure was the composite rate of stroke or death within 30 days of enrollment. Secondary outcomes included recurrent stroke, quality of life, and hemorrhagic complications. The trial found that the use of a balloon-expandable intracranial stent was associated with a lower risk of stroke or death than medical therapy alone.  