What are the outcomes of percutaneous coronary intervention with drug-eluting stent implantation versus coronary artery bypass graft for unprotected left main coronary artery lesions?
A collaborative systematic review and meta-analysis on 1278 patients undergoing percutaneous drug-eluting stenting for unprotected left main coronary artery disease showed that the two treatments were comparable in terms of clinical outcomes, with similar rates of mortality and major adverse cardiac events. However, percutaneous coronary intervention with drug-eluting stent implantation was associated with a lower rate of target vessel revascularization than coronary artery bypass grafting.