What were the effects of intensive lipid-lowering therapy on the coronary arteries of asymptomatic subjects with elevated apolipoprotein B?
The findings of the 1993 Circulation study showed that intensive lipid-lowering therapy was able to significantly reduce the amount of atherosclerosis in the coronary arteries of asymptomatic subjects with elevated apolipoprotein B. Specifically, it was found that the therapy was able to reduce the amount of fatty deposits in the arteries and also resulted in a decrease in the thickness of the artery walls. Furthermore, the study also found that the therapy was associated with a reduction in the risk of cardiovascular events, such as heart attacks and strokes.  Overall, the study concluded that intensive lipid-lowering therapy could be an effective tool for reducing the risk of cardiovascular events in asymptomatic individuals with elevated apolipoprotein B.  