What is the recommended intensity of statin use for maximal ASCVD risk reduction?
If in the context of a risk discussion, maximal ASCVD risk reduction is desired, it is reasonable to use a high-intensity statin to lower LDL-C by 50%. This provides increased benefit, especially when 10-year ASCVD risk is 20%. JUPITER enrolled men 50 years of age and women 60 years of age with high-sensitivity C-reactive protein values 2.0 mg/L and LDL-C <130 mg/dL.