What methods are used to diagnose CNE?
Molecular techniques to identify 16S ribosomal RNA or DNA from tissue or PCR to detect DNA in blood specimens are used to diagnose CNE. Commercial nucleic acid amplification tests (NAATs) do not currently target HACEK group organisms, Mycoplasma species, or zoonotic pathogens.90 Serological methods are often used to diagnose Bartonella species, T whipplei, C burnetii, and Mycoplasma species.89 Urinary antigen tests are also available for L pneumophila serogroup 1.