What is the purpose of the research discussed in ORG 10172?
The research discussed in ORG 10172 was conducted to study the pharmacokinetics and bioavailability of a low molecular weight heparinoid anticoagulant with a long half-life in humans. It also compared the effects of the antifactor Xa and IIa activities of this anticoagulant after intravenous and subcutaneous injection in rabbits, as well as its antithrombotic activity and pharmacokinetics in humans after single subcutaneous doses of 20 to 80 mg.