What evidence is there to suggest that statins are beneficial to those with HF?
Numerous retrospective analyses and small, prospective trials have demonstrated the beneficial effects of statins in patients with HF with respect to mortality and Furthermore, retrospective analyses of trials in patients with coronary artery disease but without a history of HF demonstrated a reduction in the risk of development of HF and HF hospitalizations in patients taking statins. 272 However, 2 large, prospective, randomized trials failed to confirm these beneficial effects of statins in patients with established HF.