What is the recommended anticoagulation treatment for patients with moderate CKD (Stage III, CrCl 30-59 mL/min)?
For moderate CKD (Stage III, CrCl 30-59 mL/min), we suggest oral anticoagulation in patients with a CHA2DS2-VASc 2 with label-adjusted NOACs or dose-adjusted vitamin K antagonists (Weak recommendation, very low quality evidence). Remark: With VKA, good quality anticoagulation control (TTR > 65-70%) is recommended.