What were the results of the ABCD study on normotensive patients with diabetes?
The ABCD study on normotensive patients with diabetes found that intensive treatment to a lower BP target was not associated with any difference in the change in creatinine clearance over the study period but was associated with lower risks of progression from normoalbuminuria to microalbuminuria and from microalbuminuria to overt proteinuria, as well as a reduced risk of stroke and of progression of retinopathy. The inclusion criteria for the normotensive arm of ABCD prevents reliable extrapolation of this finding to patients whose baseline BP is greater than 140/90 mm Hg.