What are the recommendations for antithrombotic treatment based on net clinical benefit for patients with AF at varying levels of stroke risk?
The recommendations for antithrombotic treatment based on net clinical benefit for patients with AF at varying levels of stroke risk are provided by systematic literature reviews that identify relevant articles published from the last formal search performed for the Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (9th Edition). The overall quality of the evidence was assessed using the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach. Graded recommendations and ungraded consensus-based statements were drafted, voted on, and revised until consensus was reached.