What are the principles guiding the inclusion and extrapolation of the results of studies on secondary stroke prevention?
The principles guiding inclusion and extrapolation of the results of studies on secondary stroke prevention are: 1. The quality of the trial/trials must be acceptable, ideally stroke or TIA occurrence or recurrence should be a prespecified end point with clear protocols for assessing stroke end points; 2. From a physiological perspective, the primary prevention strategy used in the study will likely be effective for secondary prevention; 3. Patients with ischemic stroke should be included in the population studied when possible.