What is the Trial of Org 10172 in Acute Stroke Treatment (TOAST)?
The Trial of Org 10172 in Acute Stroke Treatment (TOAST) is a clinical trial conducted by Adams HP Jr, Davis PH, Leira EC, Chang KC, Bendixen BH, Clarke WR, Woolson RF, and Hansen MD. It investigated the efficacy of t-PA for acute stroke and found that baseline NIH Stroke Scale score strongly predicts outcome after stroke.  The NIH Stroke Scale is a tool used to assess stroke severity at initial evaluation. 