What is the association between mitral-valve prolapse and stroke in young patients?
A number of studies have been conducted in order to assess the association between mitral-valve prolapse and stroke in young patients, however, the results have been inconclusive. A 1995 population-based cohort study conducted by Orencia et al. found no association between mitral valve prolapse and stroke in young patients (Stroke. 1995;26:7 13). Similarly, a 2011 study conducted by Rodriguez et al. also found no association between mitral valve prolapse and brain findings on magnetic resonance imaging in community dwelling older adults (J Am Coll Cardiol. 2011;57:2172 2180). On the other hand, a 2005 study conducted by Kizer et al. found a slight association between mitral annular calcification and incident stroke in adults free of clinical cardiovascular disease (Stroke. 2005;36:2533 2537). Therefore, it can be concluded that there is lack of evidence of an association between mitral-valve prolapse and stroke in young patients.