What is the impact of mitral annular calcification on cardiovascular events?
Kohsaka et al. (486) conducted a study to assess the impact of mitral annular calcification on cardiovascular events in a multiethnic community. They found that those with mitral annular calcification had an increased risk of stroke, as well as a higher risk of other cardiovascular events. Additionally, Roldan et al. (487) found that valvular heart disease, such as mitral annular calcification, was a cause of cerebrovascular disease in patients with systemic lupus erythematosus. Khetarpal et al. (488) also found that calcific aortic valve and spontaneous embolic stroke were associated, suggesting that mitral annular calcification may be a risk factor for stroke. Overall, the evidence suggests that mitral annular calcification is associated with an increased risk of stroke and other cardiovascular events.  