What are the benefits of using anticoagulation for the prevention of stroke in patients with mural thrombus after anterior MI?
Use of oral anticoagulation with VKA has been shown to reduce the risk of stroke by 86% and result in resolution of LV thrombus in 68% of patients with mural thrombus after anterior MI, according to a pooled meta-analysis of studies. Additionally, anticoagulation with DOACs has been shown to be as effective as VKA for the prevention of stroke in AF and for the treatment of deep vein thrombosis and pulmonary embolism, with a lower risk of bleeding and with greater convenience.