What are the advantages of using NOACs over VKAs for stroke prevention in AF?
NOACs have several advantages over VKAs for stroke prevention in AF, including a rapid onset/offset of action, absence of an effect of dietary vitamin K intake on their activity, and fewer drug interactions. Additionally, the predictable anticoagulant effects of the NOACs enable their administration in fixed doses without the need for routine coagulation monitoring, thereby simplifying therapy.