What is the effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus?
A meta-analysis of randomized controlled trials conducted by Ray KK, Seshasai SR, Wijesuriya S, Sivakumaran R, Nethercott S, Preiss D, Erqou S, and Sattar N investigated the effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus. This meta-analysis found that intensive control of glucose significantly reduced the risk of cardiovascular mortality, myocardial infarction, and stroke compared to standard care. Additionally, intensive control of glucose was associated with a significant decrease in death from any cause. These results suggest that intensive control of glucose can improve cardiovascular outcomes and reduce mortality in patients with diabetes mellitus.