What is the reasonable alternative treatment option for VGS isolates that are susceptible to ceftriaxone?
Ceftriaxone may be a reasonable alternative treatment option for VGS isolates that are susceptible to ceftriaxone (Class IIb; Level of Evidence C). Vancomycin hydrochloride 30 mg/kg per 24 h IV in 2 equally divided doses (Class IIa; Level of Evidence C) may also be used if the patient is unable to tolerate penicillin or ceftriaxone therapy.