6/30/23, 2:23 AM Text messages for smoking cessation Pathway Feedback Search Clinical Topics Home Studies Text messages for smoking cessation Text messages for smoking cessation Disease Tobacco use Trial question What is the role of text message-based smoking cessation intervention in adult smokers? Study design Multi-center Double blinded RCT Population Characteristics of study participants 1.0% female N = 722 99.0% male 722 patients (6 female, 716 male) Inclusion criteria: daily or weekly smokers 18 years of age who owned a mobile phone and used the app Key exclusion criteria: receipt of any smoking cessation treatment within 30 days and diagnosis of any mental illness Interventions N=360 personalized text messages (personalized text messages based on the transtheoretical model and protection motivation theory) N=362 nonpersonalized text messages (smoking cessation text message intervention developed by the US National Cancer Institute) https://web.pathway.md/studies/reck3HHaVzCYSW6mO 1/2 6/30/23, 2:23 AM Text messages for smoking cessation Pathway Primary outcome Biochemically verified continuous abstinence at 6 months 6.9 % 6.9 5.2 % 3.5 % 3 Significant increase 1.7 % NNH = 26 0.0 % Personalized text messages Nonpersonalized text messages Significant increase in biochemically verified continuous abstinence at 6 months (6.9% vs. 3%; OR 2.66, 95% CI 1.21 to 5.83) Secondary outcomes Significant increase in the rate of biochemically verified continuous abstinence at 3-6 months (14.7% vs. 7.7%; OR 2.24, 95% CI 1.32 to 3.81) Significant increase in biochemically verified 24-hour point prevalence of abstinence at 1 month among smokers with low nicotine dependence (11.8% vs. 7%; OR 2.15, 95% CI 1.05 to 4.38) Significant increase in biochemically verified 24-hour point prevalence of abstinence at 6 months among smokers with moderate and high nicotine dependence (14.7% vs. 5.3%; OR 4.17, 95% CI 1.34 to 3) Conclusion In daily or weekly smokers 18 years of age who owned a mobile phone and used the app, personalized text messages were superior to nonpersonalized text messages with respect to biochemically verified continuous abstinence at 6 months. Reference Haoxiang Lin, Yihua Liu, Hao Zhang et al. Assessment of a Text Message-Based Smoking Cessation Intervention for Adult Smokers in China: A Randomized Clinical Trial. JAMA Netw Open. 2023 Mar 1;6(3):e230301. Open reference URL https://web.pathway.md/studies/reck3HHaVzCYSW6mO 2/2