What study designs were accepted as evidence for this systematic review?
Intervention studies must assess pharmacologic or non-pharmacologic treatment or evaluated the variability of lipid levels over time, effectiveness of CVD risk screening, timing of repeat screening for CVD risk assessment, or risk stratification methods. For Key Question 1, SRs of RCTs or comparative observational studies and individual RCTs or comparative observational studies not included in SRs were required. For Key Question 2, SRs of clinical or lab-based observational repeated measures studies, or individual studies of these designs not included in SRs were required.