What are the potential risks of using enoxaparin in obese individuals?
The potential risks of using enoxaparin in obese individuals include an increased risk of bleeding due to the pharmacokinetics and pharmacodynamics of enoxaparin. Enoxaparin has a greater anti-factor Xa to anti-thrombin ratio in obese individuals, which can increase the risk of bleeding. Additionally, enoxaparin has a lower clearance rate in obese individuals, which can further increase the risk of bleeding.