What is the most cost effective threshold for referring patients presenting to primary care with signs and symptoms of heart failure?
The analysis suggests that a threshold of 400pg/ml of NT-proBNP is the most cost effective threshold for referring patients presenting to primary care with signs and symptoms of heart failure. This threshold produces the highest incremental QALYs and the highest incremental cost versus echo all, and has the highest net monetary benefit at 20,000 per QALY and is therefore the most cost effective diagnostic threshold.