What effect did fenofibrate have on stroke in the FIELD study?
The FIELD study assessed the effect of fenofibrate on cardiovascular events in 9795 subjects 50 to 75 years of age with type 2 diabetes mellitus who were not taking a statin therapy at study entry. Over 5 years, there was no effect on stroke with fenofibrate; however, treatment was associated with a 40% reduction in stroke in those with diabetes mellitus (HR, 0.60; 95% CI, 0.37 0.99; P= 0.046). 