what are the Recommendations for Prevention of Thromboembolism
Referenced studies that support modified recommendations are
summarized in Online Data Supplement 6.?
For patients with AF or atrial flutter of 48 hours? duration or longer, or when the duration of AF is unknown, anticoagulation with warfarin (INR 2.0 to 3.0), a factor Xa inhibitor, or direct thrombin inhibitor is recommended for at least 3 weeks before and at least 4 weeks after cardioversion, regardless of the CHADS-VASc score or the 2 2 method (electrical or pharmacological) used to restore sinus rhythm.S6.1.1-1?S6.1.1-12 MODIFIED: The 2014 AF Guideline recommendation for use of warfarin around the time of cardioversion was combined with the 2014 AF Guideline recommendation for NOACs to create a single recommendation. This combined recommendation was updated to COR I/LOE B-R from COR IIa/LOE C for NOACs in the 2014 AF Guideline on the basis of additional trials that have evaluated the use of NOACs with cardioversion.