what are the Recommendations for Antithrombotic Therapy for Prosthetic Valves
Referenced studies that support the recommendations are
summarized in Online Data Supplement 36.?
For patients with a mechanical AVR and additional risk factors for thromboembolism (eg, AF, previous thromboembolism, LV dysfunction, hypercoagulable state) or an older-generation prosthesis (eg, ball-in-cage), anticoagulation with a VKA is indicated to achieve an INR of