what are the Recommendation for Pharmacological Treatment for Stage C HFrEF:
Soluble Guanylyl Cyclase Stimulators
Referenced studies that support the recommendation are summarized
in the Online Data Supplements.?
In selected high-risk patients with HFrEF and recent worsening of HF already on GDMT, an oral soluble guanylate cyclase stimulator (vericiguat) may be considered to reduce HF hospitalization and cardiovascular death.