What are the risks for hemorrhage associated with anticoagulation?
The risks for hemorrhage associated with anticoagulation include age greater than 75 years, a history of lobar intracranial hemorrhage (ICH) suggestive of cerebral amyloid angiopathy, and certain genetic profiles or the presence of asymptomatic cerebral microbleeds on neuroimaging. For patients treated with adjusted-dose warfarin, the initial 3-month period is a particularly high-risk period for bleeding and requires close monitoring.