What is the risk of muscle injury associated with high doses of Zocor (simvastatin)?
According to the U.S. Department of Health and Human Services, there is an increased risk of muscle injury associated with high doses of Zocor (simvastatin). Studies have also found that preoperative use of statin therapy may be associated with reduced cardiac mortality after coronary artery bypass graft surgery, a lower incidence of postoperative major adverse cardiac events, and a lower incidence of postoperative atrial fibrillation. Additionally, statins may have renoprotective and infectious complication reducing effects following cardiac surgery.