What is the recommended treatment for very high-risk patients with ASCVD?
For very high-risk patients with a history of multiple major ASCVD events or one major ASCVD event and multiple high-risk conditions, high-intensity statin therapy is recommended. This includes atorvastatin 80 mg daily or rosuvastatin 20 mg daily. Additionally, ezetimibe may be used before a PCSK9 inhibitor is recommended as it is available as a generic drug and has proven safety.