What are the kinetics of intravenously administered heparin in normal humans?
The kinetics of intravenously administered heparin in normal humans was studied by de Swart CA et al. (1982). They found that the heparin was rapidly eliminated from the plasma and that the elimination half-life was approximately 1.5 hours. Additionally, Olsson P et al. (1963) found that the elimination half-life of heparin was 1.5 to 3 hours in dogs and humans, respectively.