What is the recommended treatment for patients with ICH whose INR is elevated because of VKAs?
The recommended treatment for patients with ICH whose INR is elevated because of VKAs is to have their VKAs withheld, receive therapy to replace vitamin K dependent factors and correct the INR, and receive intravenous vitamin K (Class I; Level of Evidence C). PCCs may have fewer complications and correct the INR more rapidly than FFP and might be considered over FFP (Class IIb; Level of Evidence B).