6/30/23, 2:23 AM Treadmill balance training in older adults Pathway Feedback Search Clinical Topics Home Studies Treadmill balance training in older adults Treadmill balance training in older adults Disease Falls in the elderly Trial question What is the effect of treadmill perturbation-based balance training in community-dwelling older adults? Study design Single center Open label RCT Population Characteristics of study participants 56.0% female N = 140 44.0% male 140 patients (79 female, 61 male) Inclusion criteria: community-dwelling adults 65 years of age and were able to walk without a walking aid Key exclusion criteria: orthopedic surgery within the past 12 months; osteoporosis or osteoporosis-related fractures; progressive neurological disease; an unstable medical condition preventing safe participation; severe cognitive impairment Interventions N=70 perturbation-based balance training (four 20-minute perturbation-based balance training sessions, with postural disturbances induced by sudden treadmill accelerations) https://web.pathway.md/studies/recvqSF3uO3lbvVkf 1/2 6/30/23, 2:23 AM Treadmill balance training in older adults Pathway N=70 treadmill walking training (four 20-minute regular treadmill walking sessions at the participant's preferred walking speed) Primary outcome Daily-life fall rates in past 12 months 1.1 1.14 0.9 0.9 0.6 0.3 No significant difference 0.0 Perturbation-based balance training Treadmill walking training No significant difference in daily-life fall rates in the past 12 months (0.9 vs. 1.14; RR 0.78, 95% CI 0.48 to 1.27) Secondary outcomes No significant difference in participants with at least 1 fall (49% vs. 57%; RR 0.87, 95% CI 0.63 to 1.2) No significant difference in median time to first fall (94 days vs. 123 days; HR 0.7, 95% CI 0.43 to 1.14) No significant difference in participants with at least 1 fall-related injury (24% vs. 34%; RR 0.74, 95% CI 0.43 to 1.25) Conclusion In community-dwelling adults 65 years of age and were able to walk without a walking aid, perturbation-based balance training was not superior to treadmill walking training with respect to a daily-life fall rates in the past 12 months. Reference Jens Eg N rgaard, Stig Andersen, Jesper Ryg et al. Effect of Treadmill Perturbation-Based Balance Training on Fall Rates in Community-Dwelling Older Adults: A Randomized Clinical Trial. JAMA Netw Open. 2023 Apr 3;6(4):e238422. Open reference URL https://web.pathway.md/studies/recvqSF3uO3lbvVkf 2/2