What are the effects of different blood-pressure-lowering regimens on major cardiovascular events?
The effects of different blood-pressure-lowering regimens on major cardiovascular events were studied in the Lancet publication from 2003, which found that the use of antihypertensive agents was associated with a reduction in major cardiovascular events. Specifically, the study found that the use of angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and calcium channel blockers were associated with a reduction in major cardiovascular events compared to placebo. Furthermore, the study found that the combination of two or more antihypertensive agents was associated with a greater reduction in major cardiovascular events than the use of one agent alone. These findings suggest that a combination of antihypertensive agents may be more effective than the use of one agent alone in reducing major cardiovascular events. 