What is the logic for using target BP levels in RCTs rather than the achieved BP levels observed as the basis for setting guideline targets?
The logic for using target BP levels in RCTs rather than the achieved BP levels observed as the basis for setting guideline targets is to allow conclusions to be drawn based on target BP levels rather than achieved BP levels, and to consider the evidence derived from RCTs in which patients were not randomized to BP targets but achieved BPs were reported. This approach allows for a more conservative approach to BP target setting in the Guideline.