What are the recommended antithrombotic treatments for patients with AF of 48 hours or when duration is unknown?
For patients with AF of 48 hours or when duration is unknown, it is recommended that patients receive warfarin to an INR of 2.0 to 3.0 for 3 weeks before and 4 weeks after chemical or electrical cardioversion.443 Subgroup analyses of ROCKET AF444 suggest that protection from cardioembolism around the time of cardioversion appears to be comparable for warfarin and the novel oral anticoagulants.