What are the effects of intensive glucose control on cardiovascular outcomes in patients with type 2 diabetes?
Research has demonstrated that intensive glucose control can have positive effects on cardiovascular outcomes in patients with type 2 diabetes. One study, the Action to Control Cardiovascular Risk in Diabetes Study Group, found that intensive glucose control significantly reduced the risk of death from cardiovascular causes, myocardial infarction, and stroke in patients with type 2 diabetes. Another study, the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group, found that intensive diabetes treatment significantly reduced the risk of macrovascular complications, including cardiovascular death, myocardial infarction, and stroke in patients with type 1 diabetes. Additionally, a systematic review of studies by Kelly et al. found that intensive glucose control reduced the risk of death from cardiovascular causes, myocardial infarction, and stroke in patients with type 2 diabetes. Finally, a meta-analysis by Ray et al. found that intensive glucose control significantly reduced the risk of death from cardiovascular causes in patients with diabetes mellitus.  