What were the effects of intensive glucose lowering in type 2 diabetes as reported in the N Engl J Med in 2008?
The N Engl J Med study in 2008 reported that intensive glucose lowering had beneficial effects on the vascular outcomes for patients with type 2 diabetes. The study reported that intensive glucose control was associated with a lower risk of major macrovascular events such as death from cardiovascular causes, nonfatal myocardial infarction, and nonfatal stroke. The study also found that intensive glucose control reduced the risk of microvascular events, such as the onset of diabetic nephropathy or progression of retinopathy. Additionally, the study found that intensive glucose control was associated with an increased risk of severe hypoglycemia.