Which anticoagulant drugs are suggested to be used in patients with end-stage renal disease?
In end-stage renal disease (CrCl < 15 mL/min or dialysis-dependent), we suggest using well- managed VKA with TTR > 65-70% (Ungraded consensus-based statement). NOACs should generally not be used, although in USA, apixaban 5 mg bid is approved for use in AF patients receiving hemodialysis.