What is the efficacy of IV glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide coadministered with IV alteplase?
The efficacy of the IV glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide coadministered with IV alteplase is not well established. Single-arm studies of eptifibatide as adjunctive therapy to IV alteplase support ongoing randomized controlled trials (RCTs) to establish safety and further clinical trials are needed.