What is the GRADE approach for rating the quality of the evidence for an outcome?
The GRADE approach for rating the quality of the evidence for an outcome includes assessing the study design and risk of bias, directness of the evidence, indirectness of the results, imprecision in the evidence review results, and concerns about publication bias. The final grade for the quality of the evidence for an outcome can be high, moderate, low, or very low (Table 3).