What should be included in a rating of the strength of a recommendation?
When rating the strength of a recommendation, the following should be provided: An explanation of the reasoning underlying the recommendation, including a clear description of potential benefits and harms; a summary of relevant available evidence (and evidentiary gaps), description of the quality (including applicability), quantity (including completeness), and consistency of the aggregate available evidence; an explanation of the part played by values, opinion, theory, and clinical experience in deriving the recommendation; a rating of the level of confidence in (certainty regarding) the evidence underpinning the recommendation; and a rating of the strength of the recommendation in light of the preceding bullets.