What is the minimum clinically significant benefit for continuous outcome variables?
For continuous outcome variables the minimum clinically significant benefit is taken as half the median baseline standard deviation of that variable, across all studies in the meta-analysis. If baseline values are unavailable, then half the median comparator group standard deviation of that variable will be taken as the MID. If standardised mean differences have been used, then the MID will be set at the absolute value of +0.5.