what are the Recommendations for GDMT Dosing: Sequencing and Uptitration
Referenced studies that support the recommendations are
summarized in the Online Data Supplements.?
In patients with HFrEF, titration and optimiza- tion of guideline-directed medications as frequently as every 1 to 2 weeks depending on the patient?s symptoms, vital signs, and labora- tory findings can be useful to optimize manage- ment.