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Effect of Intensive Blood Pressure Lowering on the Risk of Atrial Fibrillation. Hypertension 2020; 75:1491. Topic 1004 Version 58.0 https://www.uptodate.com/contents/epidemiology-risk-factors-and-prevention-of-atrial-fibrillation/print 30/33 7/5/23, 9:30 AM Epidemiology, risk factors, and prevention of atrial fibrillation - UpToDate GRAPHICS Prevalence of atrial fibrillation by sex and age Lifetime risk for developing atrial fibrillation (AF) from the Framingham Heart Study. Men and women without AF at 40 years of age were determined to have a 26 and 23 percent likelihood of developing incident AF by 80 years of age. Reproduced with permission from: Magnani JW, Rienstra M, Lin H, et al. Atrial brillation: Current knowledge and future directions in epidemiology and genomics. Circulation 2011; 124:1982. Copyright Lippincott Williams & Wilkins. Graphic 82929 Version 4.0 https://www.uptodate.com/contents/epidemiology-risk-factors-and-prevention-of-atrial-fibrillation/print 31/33 7/5/23, 9:30 AM Epidemiology, risk factors, and prevention of atrial fibrillation - UpToDate Prevalence of atrial fibrillation with age In a cross-sectional study of almost 1.9 million men and women, the prevalence of atrial fibrillation increases with age, ranging from 0.1 for those <55 years of age to over 9 percent in those 85 years of age. At all ages, the prevalence is higher in men than women. Data from Go AS, Hylek EM, Phillips K, et al. Prevalence of diagnosed atrial brillation in adults: National implications for rhythm management and stroke prevention: The AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. JAMA 2001; 285:2370. Graphic 77268 Version 5.0 https://www.uptodate.com/contents/epidemiology-risk-factors-and-prevention-of-atrial-fibrillation/print 32/33 7/5/23, 9:30 AM Epidemiology, risk factors, and prevention of atrial fibrillation - UpToDate Contributor Disclosures David Spragg, MD, FHRS No relevant financial relationship(s) with ineligible companies to disclose. Peter J Zimetbaum, MD Consultant/Advisory Boards: Abbott Medical [Lead extraction]. All of the relevant financial relationships listed have been mitigated. Nisha Parikh, MD, MPH No relevant financial relationship(s) with ineligible companies to disclose. Contributor disclosures are reviewed for conflicts of interest by the editorial group. When found, these are addressed by vetting through a multi-level review process, and through requirements for references to be provided to support the content. Appropriately referenced content is required of all authors and must conform to UpToDate standards of evidence. 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