What are the anticipated absolute effects of ACE-inhibitor high dose versus low dose in CKD stages 3b-4?
The anticipated absolute effects of ACE-inhibitor high dose versus low dose in CKD stages 3b-4 are: All-cause mortality (Overall risk from 52 fewer to 69 more), Mortality or Hospitalisation (Overall risk from 33 fewer to 36 more), Renal dysfunction or hyperkalaemia (from 22 more to 159 more). The quality of the evidence for these effects is VERY LOW due to risk of bias, indirectness, and imprecision.