What criteria are used to assess imprecision in the context of NICE 2018 guidance on diagnosing heart failure?
Imprecision is assessed based on inspection of the confidence region for sensitivity in the diagnostic meta-analysis. The evidence is downgraded by 1 increment when there is a 20- 40% range of the confidence interval around the point estimate, and downgraded by 2 increments when there is a range of >40%.