What was the relationship between HbA1c levels and 2-year mortality or need for urgent transplantation in a study of 358 patients with advanced HFrEF and diabetes mellitus?
In a study of 358 patients with advanced HFrEF and diabetes mellitus, the relationship between HbA1c levels and 2-year mortality or need for urgent transplantation was assessed with the use of quartiles. Quartile 1, HbA1c of 6.7% 7.1%; quartile 2, HbA1c of 7.2% - 7.8%; quartile 3, HbA1c of 7.3% - 8.5%; and quartile 4, HbA1c of 8.6% and above. Two-year event-free survival was 61% and 65% in quartiles 1 and 2 respectively, compared to 54% and 56% in quartiles 3 and 4 respectively.