What impact does oral contraceptive use have on stroke risk in women with migraine with visual aura?
A population-based, case-control study of 386 women aged 15 to 49 years with incident stroke and 614 age- and ethnicity- matched control subjects showed that women with probable migraine with visual aura who used oral contraceptives (OCs) and smoked cigarettes had 7.0-fold higher odds (95% CI, 1.3 22.8) of stroke than women with probable migraine with visual aura who did not smoke or use OCs, suggesting that the risk with both OC use and smoking in women with probable migraine with visual aura is additive.