What are the patient characteristics that generally prefer an invasive strategy?
Patients with recurrent angina or ischemia at rest or with low-level activities despite intensive medical therapy, elevated cardiac biomarkers (TnT or TnI), new or presumably new ST-segment depression, signs or symptoms of HF or new or worsening mitral regurgitation, high-risk findings from noninvasive testing, hemodynamic instability, sustained ventricular tachycardia, PCI within 6 months, prior CABG, and high-risk score (e.g. TIMI, GRACE) and mild to moderate renal dysfunction or diabetes mellitus or reduced LV function (LVEF 40%) generally prefer an invasive strategy.