What is the recommended approach when considering VKA therapy?
If VKA therapy is being considered, the SAMe-TT2R2 score can be used to identify patients who are good candidates for this approach. The VKAs are still widely used and are an acceptable alternative with target TTR $ 70%. As outlined in the section Factors Affecting INR Control, we recommend that the SAMe-TT2R2 score be used to help identify patients likely to do well on VKA therapy.