What prospective studies are needed to answer questions about the use of statins in intermediate-risk populations?
Prospective comparative studies of risk prediction strategies are needed to answer questions about the use of statins in intermediate-risk populations. Such studies should compare conventional risk assessment with CAC scoring using ultrafast computed tomography, to determine the accuracy of risk calculators and the effect of gender, ethnicity, and other factors on these risk estimates. However, such studies involve very large populations (n=30,000) and a prohibitive cost.