What is the impact of early surgery on in-hospital mortality of native valve endocarditis?
The impact of early surgery on in-hospital mortality of native valve endocarditis was studied using propensity score and instrumental variable methods to adjust for treatment-selection bias. The study, published in the Circulation journal in 2010, found that early surgery was associated with a lower in-hospital mortality. A subsequent study in 2011 by the AEPEI Study Group found that valve surgery was associated with lower short- and long-term mortality in left-sided infective endocarditis. 