What is the purpose of using CK-MB, myoglobin, and other diagnostic biomarkers for myocardial injury?
CK-MB, myoglobin, and other diagnostic biomarkers are used to detect myocardial injury. Myoglobin is a small molecule which is quickly released from infarcted myocardium and is therefore more sensitive for the detection of myocardial injury than troponin. CK-MB, on the other hand, is less sensitive for the detection of myocardial injury and requires more tissue damage for its detection. Additionally, the prognostic value associated with varying degrees of troponin elevation is still unclear, making CK-MB useful for estimating MI size. Finally, these biomarkers can be used to assess the risk of adverse outcomes in cases of troponin elevation due to reasons other than MI.  