What is the recommended treatment for established deep vein thrombosis?
Anticoagulation with a low molecular weight heparin (LMWH) is recommended as the treatment for established deep vein thrombosis (DVT). LMWH is more effective than unfractionated heparin for the treatment of DVT and is associated with less risk of bleeding. The American College of Chest Physicians (ACCP) recommends that LMWH be used for the treatment of DVT for at least 5 days, along with a vitamin K antagonist, such as warfarin, which should be continued for 3 to 6 months. Additionally, the ACCP recommends mechanical prophylaxis, such as graduated compression stockings or an intermittent pneumatic compression device, to prevent post-thrombotic syndrome. 