What is the role of angiotensin-converting enzyme inhibitors in coronary artery disease?
Angiotensin-converting enzyme inhibitors (ACEIs) are widely used in the treatment of coronary artery disease. They are thought to reduce the risk of cardiovascular events such as myocardial infarction and stroke by reducing blood pressure, improving coronary artery perfusion, and decreasing inflammation. Studies have also suggested that ACEIs may reduce the risk of sudden cardiac death, even in patients without heart failure. ACEIs may also improve left ventricular function and reduce the risk of developing heart failure in patients with coronary artery disease and preserved left ventricular systolic function. Additionally, ACEIs may reduce the risk of major adverse cardiovascular events in patients with coronary artery disease and normal blood pressure. 