What was the effect of carvedilol on survival in severe chronic heart failure?
The Effect of Carvedilol on Survival in Severe Chronic Heart Failure was studied in a 2001 New England Journal of Medicine publication. The study found that carvedilol, a nonselective beta-blocker, significantly improved survival in patients with severe chronic heart failure compared to placebo. The mortality rate was reduced by 17%, and the number of hospitalizations for heart failure was also reduced significantly. These results demonstrate the potential benefits of carvedilol in the management of severe chronic heart failure.  