What is the natural history of radiographically defined vertebrobasilar nonsaccular intracranial aneurysms?
Flemming et al. studied the natural history of radiographically-defined vertebrobasilar nonsaccular intracranial aneurysms in a cohort study published in Cerebrovascular Diseases in 2003. The study found that aneurysm growth was observed in 30% of the patients and a total of 8 (13%) patients had aneurysm-related complications such as subarachnoid hemorrhage, thrombosis, and aneurysm rupture during the follow-up period of 3.8 years. The authors concluded that aneurysms in the vertebrobasilar system may remain stable or grow over time, and that aggressive surveillance and treatment may be warranted for those at risk of aneurysm-related complications.