What are the risk factors for bleeding while on VKA therapy?
The risk factors for bleeding while on VKA therapy include older age, renal dysfunction, anemia, thrombocytopenia, a history of stroke or transient ischemic attack, a history of bleeding or a bleeding diathesis, concomitant use of drugs that increase the risk of bleeding (e.g., nonsteroidal anti-inflammatory drugs, aspirin, clopidogrel, warfarin), and alcohol abuse.