What is the evidence that treating patients with ischemic stroke and evidence of atherosclerosis to an LDL target of <70 mg/dL is more effective in stroke prevention than less intensive lipid management?
There is evidence that treating patients with ischemic stroke and evidence of atherosclerosis to an LDL tar- get of <70 mg/dL is more effective in stroke preven- tion than less intensive lipid management.210 Detailed guidance for lipid management based on age and very high-risk status is presented elsewhere in this docu- ment (see Section 4.3, Treatment of Hyperlipidemia for Secondary Prevention of Stroke). Many patients with aortic plaque and ischemic stroke will meet the criteria for very high-risk status because of concomi- tant atherosclerotic conditions and risk factors.