What are the risk factors for bleeding while on VKA therapy?
The risk factors for bleeding while on VKA therapy include age, renal impairment, low body weight, certain medical conditions (e.g. uncontrolled hypertension, thrombocytopenia, hematologic disorders, and hepatic dysfunction), concomitant use of other anticoagulants, or concomitant use of non-steroidal anti-inflammatory drugs (NSAIDs) or platelet inhibitors.