What antibiotic regimen is recommended for infective endocarditis in children caused by penicillin-susceptible streptococci?
A 4-week regimen of intravenous aqueous crystalline penicillin G (or ampicillin if penicillin G is unavailable) is recommended for infective endocarditis in children caused by penicillin-susceptible streptococci. This approach avoids aminoglycoside-containing regimens for children with impairment of renal function, concurrently administered nephrotoxic drugs, or eighth cranial nerve impairment.