What is the purpose of the SIGNAL-HF trial?
The purpose of the SIGNAL-HF trial is to evaluate the efficacy of NP monitoring (in primary care) to increase treatment to achieve a target of 50% reduction of NT-proBNP levels from baseline, over a 9-month period, in patients with age mean of 78 (7), NYHA class II-IV, and LVEF < 50%, who are stable in primary care and have elevated NPs (NT- proBNP levels males > 800, females > 1000 ng/L).