What is the recommended approach for evaluating lipid profiles in adults aged 20 and older?
In adults who are 20 years of age or older, measurement of either a fasting or a nonfasting plasma lipid profile is effective in estimating ASCVD risk and documenting Table 2. For adults with an LDL-C level less than 70 mg/dL (<1.8 mmol/L), measurement of direct LDL-C or modified LDL-C estimate is reasonable to improve accuracy. In adults who are 20 years of age or older and without a personal history of ASCVD, but with a family history of premature ASCVD or genetic hyperlipidemia, measurement of a fasting plasma lipid profile is reasonable as part of an initial evaluation to aid in the understanding and identification of familial lipid disorders.