What is the Framingham Stroke Profile?
The Framingham Stroke Profile (FSP) is a model that uses a Cox proportional hazards model with risk factors as covariates and points calculated according to the weight of the model coefficients. Independent stroke predictors include age, systolic blood pressure (SBP), hypertension, diabetes mellitus, current smoking, established cardiovascular disease (CVD; myocardial infarction [MI], angina or coronary insufficiency, congestive heart failure, and intermittent claudication), atrial fibrillation (AF), and left ventricular hypertrophy on ECG. The FSP is used to estimate sex-specific, 10-year cumulative stroke risk and has been updated to account for the use of antihypertensive therapy and the risk of stroke and stroke or death among individuals with certain conditions.