What are the features of the newer anticoagulants compared to warfarin?
The newer anticoagulants offer several attractive features in comparison to warfarin, including a fixed dose, no required blood monitoring, no known interactions with immune complexes associated with heparin-induced, and fewer drug interactions. Additionally, these agents have been shown to have a lower risk of intracranial hemorrhage than warfarin. However, they have some drawbacks, such as a higher cost, renal clearance, short half-lives, no monitoring test to ensure compliance, and lack of a specific agent to reverse their anticoagulant effects.