What effects does atorvastatin have on kidney outcomes and cardiovascular disease in patients with diabetes?
A post-hoc analysis from the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study found that long-term statin treatment had a safety and efficacy for cardiovascular events in patients with coronary heart disease and abnormal liver tests. A systematic review and meta-analysis conducted by Palmer et al. (2012) suggested that statin therapy may provide a benefit for persons with chronic kidney disease. A separate analysis from the Collaborative Atorvastatin Diabetes Study (CARDS) found that atorvastatin had positive effects on kidney outcomes and cardiovascular disease in patients with diabetes. Finally, a study conducted by Asselbergs et al. (2004) found that fosinopril and pravastatin were effective in reducing cardiovascular events in subjects with microalbuminuria.