What are the effects of intensive blood pressure lowering on kidney tubule injury?
Studies have shown that intensive blood pressure lowering can have beneficial effects on kidney tubule injury. A longitudinal subgroup analysis in the SPRINT trial found that intensive blood pressure lowering was associated with reduced kidney tubule injury in people with chronic kidney disease. The ACCORD Trial study participants also found that intensive blood pressure lowering had a protective effect against kidney tubule injury. Furthermore, a case-control study found that blood pressure reduction had a positive effect on kidney damage biomarkers and incident chronic kidney disease.