What are the benefits of using ticagrelor instead of clopidogrel?
Ticagrelor has a more rapid and consistent onset of action and, because it is reversible, it has a faster recovery of platelet function. Compared with clopidogrel, ticagrelor has been shown to reduce the composite outcome of death from vascular causes, MI, or stroke, as well as the mortality rate in patients with NSTE-ACS. Major bleeding was not increased with ticagrelor, although a modest increase in major bleeding and non procedure-related bleeding occurred in the subgroup of patients who did not undergo CABG.