What is the effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus?
A meta-analysis of randomized controlled trials found that intensive control of glucose had a positive effect on cardiovascular outcomes and death in patients with diabetes mellitus. The study found that intensive glucose control reduced the risk of major cardiovascular events by 14%, reduced the risk of all-cause mortality by 12%, and reduced the risk of non-fatal myocardial infarction by 17%. Additionally, intensive glucose control reduced the risk of stroke by 18% and reduced the risk of microvascular complications by 22%. These findings suggest that intensive control of glucose is beneficial in reducing the risk of cardiovascular outcomes and death in patients with diabetes mellitus.