What is statin-associated autoimmune myopathy?
Statin-associated autoimmune myopathy is a rare disorder that is characterized by muscle weakness, marked and persistent creatine kinase (CK) elevation, presence of HMG CoA reductase (HMGCR) antibodies, necrotizing myopathy, and lack of or incomplete resolution on statin discontinuation. It requires statin cessation and additional therapy directed at the autoimmune process, and patients may benefit from seeing a neurologist specializing in neuromuscular disorders.