What is the GRADE system for grading the quality of evidence?
The GRADE system is a system used to assess and evaluate the quality of evidence in medical research. It grades the quality of evidence based on the study design, strength of association, consistency, indirectness, imprecision, and publication bias. The overall quality of the evidence is graded from A to D, with A representing the highest quality of evidence and D the lowest. It is used to determine the strength of a recommendation for clinical practice.  