What is the evidence of the effects of an SBP target of <120 mm Hg versus <140 mm Hg in patients with CKD without diabetes?
Evidence of the effects of an SBP target of <120 mm Hg versus <140 mm Hg in patients with CKD without diabetes is available only from SPRINT. According to SPRINT, there were 53 deaths per 1000 participants in the standard BP control arm, and 40 deaths per 1000 participants in the intensive BP control arm, resulting in a statistically significant difference of 13 fewer per 1000 participants; Supplementary Table S1191,93 ) This difference is also evident when the CKD subgroups in both ACCORD (comprised all patients with diabetes) and SPRINT (comprised no patients with diabetes) are combined.