What are the benefits of lowering blood pressure to <130/80 mmHg among adults with diabetes mellitus?
Several meta-analyses of randomized controlled trials (RCTs) have demonstrated that lowering blood pressure to a target of <130/80 mmHg provides significant benefit compared to a target of 140/81 mmHg for major cardiovascular events, myocardial infarction, stroke, albuminuria, and retinopathy progression. Additionally, a secondary analysis of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial demonstrated a significant outcome benefit of stroke risk reduction in the intensive BP/standard glycemic group.