What is the improvement in NYHA class after treating chronic heart failure?
Data on improvement in NYHA has only been extracted where quality of life data is not reported in a trial. The relative effect is VERY LOWa, b, c due to risk of bias, indirectness, imprecision (from 144 fewer to 1000 more). The risk with placebo is LOWa,c due to risk of bias, indirectness and the Peto Odds is (from 450 fewer to 50 more). The risk difference with intravenous iron (95% CI) is MODERATE b due to imprecision.