What is the recommended dose of enoxaparin for NSTE-ACS?
The recommended dose of enoxaparin for NSTE-ACS is 1 mg/kg SC every 12 hours, with an initial intravenous loading dose of 30 mg used in selected patients. In the presence of impaired renal function (CrCl <30 mL per minute), which is a common finding in older patients, the dose should be reduced to 1 mg/kg SC once daily, and strong consideration should be given to UFH as an alternative. Calculation of CrCl is prudent in patients considered for enoxaparin therapy.