What factors were found to be an independent risk factor for VTE recurrence in the study?
Previous VTE was the only significant predictor of recurrence with multivariate analysis (hazard ratio [HR], 2.70; 95% CI, Many of the recurrent VTEs occurred in women when the first CVT occurred during pregnancy/ puerperium or was secondary to OC or HT use; however, neither female sex (HR, 1.37; 95% CI, 0.83 2.25), pregnancy/ puerperium (HR, 1.05; 95% CI, 0.48 2.28), or use of OC/HT (HR, 0.72; 95% CI, 0.45 1.14) was an independent risk factor for VTE recurrence.199 This was in contrast to the results from a study by Martinelli et al,197 which found that male sex was a risk factor for recurrence (HR, 9.66; 95% CI, 2.86 32.7).