What safety and efficacy studies have been done regarding the coadministration of IV glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide with IV alteplase?
Single-arm studies of eptifibatide as adjunctive therapy to IV alteplase have been done to support ongoing randomized controlled trials (RCTs) to establish the safety and efficacy of the coadministration of IV glycoprotein IIb/IIIa inhibitors tirofiban and eptifibatide with IV alteplase. Further clinical trials are needed. See Table XXXIX in online Data Supplement 1.