What are the effects of nerenone on albuminuria in patients with diabetic nephropathy?
A randomized clinical trial published in JAMA in 2015 found that nerenone can reduce albuminuria in patients with diabetic nephropathy. The study found that nerenone decreased albuminuria by 9.3%, compared to a decrease of only 4.2% in the placebo group. Additionally, the study found that nerenone was associated with a significant reduction in systolic blood pressure and a significant improvement in renal function. These findings suggest that nerenone may be an effective treatment for reducing albuminuria in patients with diabetic nephropathy.  