What is the efficacy of Ranolazine in treating chronic angina?
Several studies have been conducted to assess the efficacy of Ranolazine in treating chronic angina. A randomized controlled trial published in the Journal of the American Medical Association (JAMA) in 2004 found that Ranolazine was more effective than atenolol in improving exercise tolerance and reducing angina frequency in patients with severe chronic angina. A large-scale comparative study in general practice published in the European Journal of Clinical Pharmacology in 1992 found that sublingual nitroglycerin or spray formulations were more effective than tablet formulations in elderly patients with angina pectoris. The ERICA (Efficacy of Ranolazine in Chronic Angina) trial published in the Journal of the American College of Cardiology in 2006 showed that Ranolazine was effective in reducing angina frequency when added to treatment with amlodipine. Overall, the evidence suggests that Ranolazine is an effective treatment for chronic angina. 