Guideline sources The following summarized guidelines for the evaluation and management of social anxiety disorder (SAD) are prepared by our editorial team based on guidelines from the Anxiety Disorders Association of Canada (ADAC 2014). 2 Guidelines 1. Medical management Antidepressants: as per ADAC 2014 guidelines, citalopram was found to be significantly more effective than placebo, and as effective as moclobemide in randomized control trials. B Benzodiazepines: as per ADAC 2014 guidelines, in the treatment of SAD, randomized control trials have demonstrated effectiveness for the benzodiazepine clonazepam. A Anticonvulsants: as per ADAC 2014 guidelines, in a randomized control trial, gabapentin was significantly more effective than placebo, and as effective as tiagabine in a small cross-over study. B Other therapeutic agents: as per ADAC 2014 guidelines, olanzapine was effective in a small RCT. B Show 2 more 2. Follow-up and surveillance https://web.pathway.md/diseases/recu5Sps1g9alFV49 1/2 6/24/23, 3:14 PM Social anxiety disorder Pathway Management of refractory disease: as per ADAC 2014 guidelines, adjunctive therapy with aripiprazole, risperidone, buspirone, or paroxetine may benefit patients with refractory SAD, as suggested by open-label studies and case series. B References 1. David S Baldwin, Ian M Anderson, David J Nutt et al. Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology. J Psychopharmacol. 2014 May;28 5 403 39. Open 2. Katzman MA, Bleau P, Blier P et al. Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders. BMC Psychiatry. 2014;14 Suppl 1 S1. Open 3. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision DSM 5 TR ). APA. 2022. Open https://web.pathway.md/diseases/recu5Sps1g9alFV49 2/2