6/29/23, 11:57 PM STRIDE Pathway Feedback Search Clinical Topics Home Studies STRIDE STRIDE Disease Falls in the elderly Trial question What is the effect of implementation of a supervised walking program in hospitalized community- dwelling older adults? Study design Multi-center Open label RCT Population Characteristics of study participants 3.0% female N = 12863 97.0% male 12863 patients (521 female, 16716 male) Inclusion criteria: adults patients 60 years of age who were community-dwelling and hospitalized for 2 days Key exclusion criteria: index hospital stay < 2 business days; current hospitalization; current high- risk suicide flag in medical record; diagnosis of cognitive impairment or dementia Interventions N=6722 STRIDE (implementation of a supervised walking program known as assisted early mobility for hospitalized veterans) N=6141 usual care (pre-implementation before STRIDE program) https://web.pathway.md/studies/rectEgwqbphX8p3k9 1/2 6/29/23, 11:57 PM STRIDE Pathway Primary outcome Discharge to a skilled nursing facility 13.0 % 13 9.8 % 8 6.5 % 3.3 % Borderline significant decrease 0.0 % STRIDE Usual care Borderline significant decrease in discharge to a skilled nursing facility (8% vs. 13%; OR 0.6, 95% CI 0.5 to 0.8) Secondary outcomes No significant difference in length of hospital stay (6.92 days vs. 6.58 days; RR 1.05, 95% CI 0.97 to 1.15) No significant difference in physical function-disability, measured by Late Life Function and Disability Instrument (67.31 vs. 65.99; MD 1.32, 95% CI -2.7 to 5.33) No significant difference in physical function-limitations, measured by Late Life Function and Disability Instrument (65.67 vs. 64.12; MD 1.56, 95% CI -3.14 to 6.25) Conclusion In adults patients 60 years of age who were community-dwelling and hospitalized for 2 days, STRIDE was superior to usual care with respect to discharge to a skilled nursing facility. Reference Susan N Hastings, Karen M Stechuchak, Ashley Choate et al. Effects of Implementation of a Supervised Walking Program in Veterans Affairs Hospitals : A Stepped-Wedge, Cluster Randomized Trial. Ann Intern Med. 2023 Jun 6. Online ahead of print. Open reference URL https://web.pathway.md/studies/rectEgwqbphX8p3k9 2/2