What is the recommended target INR for patients with valvular atrial fibrillation at high risk for stroke?
For patients with valvular atrial fibrillation at high risk for stroke, defined as a CHA2 - VASc score of 2, and acceptably low risk for hemorrhagic complications, chronic oral anticoagulant therapy with warfarin at a target INR of 2.0 to 3.0 is recommended (Class I; Level of Evidence A).