What is the SAMe-TT2R2 score?
The SAMe-TT2R2 score is a risk stratification tool used to predict anticoagulation control in patients with atrial fibrillation who are taking vitamin K antagonists, such as warfarin. The score combines seven factors - sex, age, medical history, treatment, tobacco use, race, and risk (SAMe-TT2R2) - to provide a score that predicts the quality of anticoagulation control. Studies have shown that the SAMe-TT2R2 score is correlated with improved time to therapeutic range (TtTR), anticoagulation control, and cardiovascular events in vitamin K antagonists-naive patients with atrial fibrillation.  