What medications are recommended for patients with NSTE-ACS with continuing ischemic pain?
Patients with NSTE-ACS with continuing ischemic pain should receive sublingual nitroglycerin (0.3 mg). Additionally, the use of IV morphine sulfate and beta-blockers, as well as non-dihydropyridine calcium channel blockers (CCBs) may be reasonable for continued ischemic chest pain despite maximally tolerated anti-ischemic medications. Long-acting CCBs and nitrates are recommended for patients with coronary artery spasm. Immediate-release nifedipine is contraindicated in the absence of a beta blocker.