What is the recommendation for using aspirin for cardiovascular prevention among those with diabetes mellitus?
A focused, multisociety position paper on the primary prevention of cardiovascular events in people with diabetes mellitus recommended that low-dose aspirin be used for adults with diabetes mellitus who have a 10-year cardiovascular risk >10% (men >50 years of age and women >60 years of age who have at least 1 additional major risk factor such as smoking, hypertension, dyslipidemia, a family history of premature CVD, or albuminuria) and who are not at high risk of aspirin-related bleeding complications. It was further recommended that aspirin not be used for cardiovascular prevention among those with diabetes mellitus at low risk and that aspirin might be considered for those at intermediate (10-year risk in the 5%-10% range) risk. Relatively few women were enrolled in the primary prevention trials that showed a benefit of aspirin in the prevention of coronary heart events but no reduction in stroke.