What is the recommended oral anticoagulant therapy for patients with valvular AF at high risk for stroke?
For patients with valvular AF at high risk for stroke, defined as a CHA2 -VASc score of 2 and acceptably low risk for hemorrhagic complications, long-term oral anticoagulant therapy with warfarin at a target INR of 2.0 to 3.0 is recommended (Class I; Level of Evidence A).