What medications are recommended to treat hypertension in patients with HF?
In patients with hypertension and HF with reduced EF (HFrEF), drugs that have been shown to improve outcomes for patients with HF generally also lower BP. Thus, the emphasis should be on initiating and optimizing guideline-directed medical treatment of HF, which will likely help control BP at target doses. Therefore, patients with hypertension and HF with reduced EF (HFrEF) are treated with diuretics, ACE inhibitors (or ARBs if ACE inhibitor intolerant), -blockers, and aldosterone antagonists unless contraindicated8 (Table 4). Although thiazide or thiazide-like diuretics are usually recommended for the treatment of hypertension,7 in patients with current or prior symptoms of HF who have evidence of fluid retention, loop diuretics are usually used8 (Table 4). 