What is the comparative effectiveness of the 3 main drug classes used for rate control (beta-blockers, calcium-channel blockers and digoxin) in people aged 75 and over with atrial fibrillation in controlling symptoms, improving quality of life and reducing morbidity and mortality?
The clinical and cost effectiveness of the 3 main drug classes used for rate control (beta-blockers, calcium-channel blockers and digoxin) in people aged 75 and over with atrial fibrillation in controlling symptoms, improving quality of life and reducing morbidity and mortality has not been fully evaluated. A systematic review of the literature and meta-analysis of the available data is needed to determine the comparative effectiveness of each of the drug classes in people aged 75 and over with atrial fibrillation.