What are the long-term risks associated with intensive blood pressure lowering in patients with type 2 diabetes mellitus?
A study by Ku et al. (2018) found that acute declines in renal function during intensive BP lowering were associated with an increased risk of long-term death in patients with type 2 diabetes mellitus. Additionally, a study by Collard et al. (2018) found that a creatinine rise during blood pressure therapy was associated with an increased risk of adverse clinical outcomes in patients with type 2 diabetes mellitus.  