What is the effect of statin therapy on the prevention of cardiovascular events?
Statins have been shown to reduce the risk of cardiovascular events in multiple trials. A meta-analysis of >40,000 patients found that intensive statin therapy was associated with a greater reduction in cardiovascular events compared to moderate statin dosing. A meta-analysis of the Cholesterol Treatment Trialists' (CTT) Collaborators found that statins were associated with a significant reduction in risk of cardiovascular events in people at low risk of vascular disease.