What is the best approach for periprocedural anticoagulation for catheter ablation and implantable devices?
Uninterrupted warfarin is generally recommended to be the best approach for periprocedural anticoagulation for catheter ablation and implantable devices. Randomized trials have shown that uninterrupted warfarin is safe and superior to warfarin interruption for implantation of cardiac implantable electronic devices. Additionally, a randomized trial of uninterrupted rivaroxaban vs uninterrupted VKA in AF ablation demonstrated similar event rates in both arms, and a similar randomized trial of uninterrupted dabigatran found that dabigatran was associated with fewer bleeding complications than uninterrupted warfarin.