Hi @ptrblck
I’ve run all the three datasets again. Now the accuracy values of training, validation, and test sets before and after loading the best model keep the same for the three tasks, but for ADvsMCI, the accuracy values of training, validation, and test  sets are always 1.0 at the first epoch, even if I use different models such as ResNet18, ResNet34, and Inceptionv3.
Do you have any idea about the abnormal learning process? Thank you very much.