If I do a setup with python virtualenv then will this work , because I tried to setup  and also I changed my conf file below is my conf file

This file was installed by nvidia-450

Do not edit this file manually
blacklist nouveau
blacklist lbm-nouveau
blacklist nvidia-current
blacklist nvidia-173
blacklist nvidia-96
blacklist nvidia-current-updates
blacklist nvidia-173-updates
blacklist nvidia-96-updates
blacklist nvidia-450-updates
alias nvidia nvidia_450
alias nvidia-uvm nvidia_450_uvm
alias nvidia-modeset nvidia_450_modeset
alias nvidia-drm nvidia_450_drm
alias nouveau off
alias lbm-nouveau off
options nvidia_450_drm modeset=0
options nvidia “NVreg_RestrictProfilingToAdminUsers=0”
options nvidia “NVreg_RestrictProfilingToAdminUsers=1”
but it is still not working