_:n65644bbcd1ca4dae9183ec5070fa3b35xb1
<http://schema.org/image>
<https://media.springernature.com/lw1200/springer-static/image/art%3A10.1186%2Fs13073-022-01065-3/MediaObjects/13073_2022_1065_Fig1_HTML.png>
<https://link.springer.com/article/10.1186/s13073-022-01065-3>