_:n772fa7a148b44a9abe4cbeb8a964a4baxb0
<http://schema.org/description>
"  \t  \t&nbsp;        Tropomyosin/Troponin&nbsp;      \t(Actin Binding Protein)  \tCat. #: 8321-01&nbsp;        \t.............................................................................................................................................................................................................................................................................................................................................................................................................        \t  \t&nbsp;Description        \t  \t\t  \t\t\t&nbsp;  \t\t\t&nbsp;  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tProtein  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tTropomyosin-Troponin (Synonym: native Tropomyosin)&nbsp;  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tOrigin  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tSkeletal muscle, rabbit  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tMolecular mass  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\t~148kDa  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tMolecular structure  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tTropomyosin (2x35kDa), Troponin T (37kDa),Troponin I (23kDa),Troponin C (18kDa).&nbsp;&nbsp;&nbsp;  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tActin interaction  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tCa++-sensitive, regulatory laterally F-actin binding complex. Molar ratio = 1:7 (tropomyosin/troponin:g-actin).  \t\t\t  \t\t\t  \t\t  \t        \t  \t  \tProperties        \t  \t\t  \t\t\t&nbsp;  \t\t\t&nbsp;  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tForm  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tLyophilized, ready-to-use.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tQuantity&nbsp;per unit  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\t2x100 &micro;g  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tBuffer  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\t0.1M KCl, 20mM imidazole pH 7.4, 1mM EDTA, 2mM DTT and 2% disaccharides, when reconstituted with 100&micro;l ultrapure water to obtain a 1mg/ml solution.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tPurity  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\t&gt;95%&nbsp;by scanning densitometry.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tPurification notes  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tPurified from rabbit skeletal muscle.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tProtein concentration  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tDetermined by the Biuret method.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tStorage instructions  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tTropomyosin/Troponin is stored at &ndash;70&deg;C upon arrival will be stable in performance for at least 6 months from the date of purchase. The solubilized complex is kept on ice and should be used within 1&nbsp;week.  \t\t\t    \t\t\t  \t\t\t\t  \t\t\t\tThis product can also be stored as a glycerol stock at -20&deg;C. Avoid repeated freeze / thaw cycles.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tShipping conditions&nbsp;  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tAt ambient temperature. Upon delivery store at -70&deg;C.  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tRemarks  \t\t\t  \t\t\t  \t\t\t  \t\t\t  \t\t\t\tFor Use in Research only. Not for Use in Human or Veterinary Diagnostical or Therapeutical Applications.&nbsp;  \t\t\t  \t\t\t  \t\t  \t\t  \t\t\t  \t\t\t  \t\t\t\tCAS no.  \t\t\t  \t\t\t  \t\t\t&nbsp;  \t\t  \t        \t  \t  \t  \tFurther Information  \t  \tProduct DataSheet  \t  \tMaterial and Safety Data Sheet  \t&nbsp;        \tProtein Sequences and Structures on RCSB  \t  \tThe PDB link contains the sequences of troponins, tropomyosin and actin from skeletal muscle (rabbit and chicken) and were given in the publication cited below.  \t  \t  \t&nbsp;  \t  \t\tReferences  \t  \t     \t  \t\t  \t\t\t  \t\t\t\t  \t\t\t\t\t  \t\t\t\t\t\tElectron tomography of cryofixed, isometrically contracting insect flight muscle reveals novel actin-myosin interactions.  \t\t\t\t\t    \t\t\t\t\t  \t\t\t\t\t\tWu S, Liu J, Reedy MC, Tregear RT, Winkler H, Franzini-Armstrong C, Sasaki H, Lucaveche C, Goldman YE, Reedy MK, Taylor KA  \t\t\t\t\t\tPlos One (2010) 5 p.126433  \t\t\t\t\t  \t\t\t\t    \t\t\t\t  \t\t\t\t\t&nbsp;  \t\t\t\t  \t\t\t  \t\t  \t  \t     &nbsp;      \t&nbsp;  "
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