_:n5c24e581e27f417d93bd7d3ae71ba2d5xb1
<http://schema.org/description>
"Next-generation DNA sequencing technologies such as Illumina's Solexa platform and Roche's 454 approach provide new avenues for investigating genome-scale questions. However, they also present novel analytical challenges that must be met for their effective application to biological questions. Here we report the availability of tileQC, a tile-based quality control system for Solexa data written in the R language. TileQC provides a means of recognizing bias and error in Solexa output by graphically representing data generated by flow cell tiles. The data represented in the images is then made available in the R environment for further analysis and automation of error detection. TileQC offers a highly adaptable and powerful tool for the quality control of Solexa-based DNA sequence data."
<https://bmcbioinformatics.biomedcentral.com/articles/10.1186/1471-2105-9-250/figures/3>