<https://www.acne.org/forums/topic/343456-oestrogen-testosterone-progesterone-questions-and-saw-palmetto/#comment-7>
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"Hormones are very hard to understand... the thing I know for sure is that synthetic hormones (such as progesterone) are not the same as natural hormones that the body produces. Everyone's adrenals make progesterone, but it's only the progesterone pill that causes acne...why? Because it's synthetic, and also because there are other ingredients involved. The body still can't recognize synthetic hormones as its own, that's why there is usually a long adjustment period, but on the flip side, the body can become too reliant on synthetic hormones to function on its own. \nAs for estrogen, there are 3 types (maybe more?) of estrogen, and one is the \"bad\" type...the one that increases risks of cancer and other symptoms. DIM is basically a high concentration of broccoli, and helps detoxify the bad estrogens that we get from plastic, soy, and the environment. Bad estrogen (I believe it's E1) is not to be confused with good estrogen (E2, if I remember correctly). Menopausal women can still have high levels of E1, and still have low overall estrogen levels. (E2 and/or E3).  \nIf your cycles are normal, though, I don't recommend messing with your hormones at all.  \n"
<https://www.acne.org/forums/topic/343456-oestrogen-testosterone-progesterone-questions-and-saw-palmetto/>