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"@Altostrata this was the introduction of the varying beads question. I also outlined my conversation with the pharmacist about the powder in the posts above, and I contacted PCCA by phone to confirm that they do in fact make Duloxetine powder for compounding, as well as liquid duloxetine\n \n\n\n\t \n \n\n\n\tFor the other parts of your question: What the pharmacist told me is that the PCCA formula for the powder/capsule version uses a coated capsule like the coated capsule that is normally used, and that there is also a filler they use to help facilitate slower release. I’m not sure exactly how that does that, but she was saying that because of these different components the action of the medicine should be the same: it passes through the stomach and the capsule begins to dissolve in the intestines. \n \n\n\n\t \n \n\n\n\tIn the commercial capsules available 20mg and up, don’t they only start to dissolve in the intestines as well?\n \n\n\n\tThe info I have read on this site would seem to suggest that BOTH the capsule AND the beads have coating to withstand stomach acid...\n \n\n\n\t \n \n\n\n\t \n \n\n\n\tI have emailed PCCA Attn: the Clinical Compounding Pharmacist with my question about the bead designs varying and if I get a response I will also ask about their capsule design. \n "
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