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"   What is it used for?  Treatment of allergic rhinitis    How does it work? Tramazoline hydrochloride belongs to a group of medicines called sympathomimetics, which work by stimulating alpha-receptors in certain areas of the body. When applied as a nasal spray, tramazoline acts on the alpha receptors in the walls of blood vessels in the nose. This causes them to narrow and results in less blood travelling through the vessels in the nose. This in turn, decreases the amount of fluid pushed out into the nasal lining, and so reducing mucus secretion    Dexamethasone belongs to a group of medicines known as corticosteroids, used for reducing inflammation. Inflammation occurs as a result of allergy or irritation and is caused by the release of substances that are important in the immune system. These substances cause blood vessels to widen, resulting in the affected area becoming red, swollen, itchy and painful. Dexamethasone when applied as a nasal spray works by acting within cells to decrease the release of these substances in the nose, thereby reducing swelling, redness and itch.    Individuals who suffer from allergies, such as hayfever (allergic rhinitis), tend to experience a variety of symptoms including runny nose, itchy eyes and sneezing. These symptoms occur due to inflammation of the nasal passage. This forces fluid out of the nasal tissues resulting in a runny and blocked nose. Tramazoline and dexamethasone work in combination in this product to narrow the blood vessels in the nose and prevent the release of substances which cause inflammation. The overall effect of this is to relieve the symptoms of nasal allergies such as hayfever.   Warning!  The effect of this medicine will decrease if used repeatedly over a period of time. In addition, a return of nasal congestion (rebound congestion) may occur on stopping treatment if the medicine was used for too long. Avoid contact of this medicine with the eyes. Each course of treatment should not exceed 14 days. Discard 6 months after opening    Not to be used in  Breastfeeding Children under 5 years of age  This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.   If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.   Pregnancy and Breastfeeding Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.  The safety of this medicine during pregnancy has not been established. Seek medical advice from your doctor. This medicine should not be used by breastfeeding mothers. Discuss this with your doctor.    Side effects Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.  Burning sensation Sneezing  The side effects listed above may not include all of the side effects reported by the drug&amp;#039;s manufacturer.   For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.   How can this medicine affect other medicines? There are no significant interactions reported with this medicine when applied to the nose. Last updated 08.07.2004 "^^<http://www.w3.org/2001/XMLSchema#string>
<http://www.netdoctor.co.uk/medicines/allergy-and-asthma/a6548/dexa-rhinaspray-duo-discontinued-in-the-uk-july-2007/>