Liverpool midfield man Boudewijn Zenden will be out for six weeks after undergoing surgery on his knee.
Zenden joins a lengthy Liverpool casualty list
The 30-year-old suffered medial knee ligament damage in Saturday's 1-0 win against Manchester City.
Zenden missed much of last season with a knee injury, but boss Rafael Benitez said it was not the same problem.
He said: "Because it is the same knee, the decision has been made that he must have the operation. He will be out for between four and five weeks."
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Zenden's injury is the latest setback to hit Liverpool's depleted midfield, with Xabi Alonso and Mohamed Sissoko ruled out with long-term problems.
He is added to a casualty list that also incluldes Mark Gonzalez, Harry Kewell, Stephen Warnock and Fabio Aurelio.