A study into the possible effects of climate change found parts of Norfolk and Cambridgeshire could be among the best and worst places to live.
The Fens could be more vulnerable to flooding
Climatologist Dr David Viner examined how changes could impact on England.
He found extreme storms could increase the vulnerability of Happisburgh cliffs, in Norfolk, where 26 homes have already fallen into the sea.
The Fens could also be more vulnerable to flooding in extreme weather and increased winter rain, Dr Viner said.
His findings will be shown on the BBC Inside Out programme Climate Change Now on Friday.
While coastal areas of Norfolk and the inland Fens are named among the most at-risk areas, inland areas of Norfolk like Holt and Fakenham will benefit from warmer winters and drier summers.
With the low density of population, water resource problems are not likely to be an issue, Dr Viner, a senior scientist at the University of East Anglia's Climatic Research Unit, found.
The programme also explores the wildlife winners and losers, as birds and plants migrate northwards pushing out some native species.