Six Labour MPs have retired - some like Welsh First Minister Rhodri Morgan to concentrate on their work as assembly members - along with two Plaid Cymru MPs and one Liberal Democrat.
Three of them, Barry Jones( Alyn and Deeside), Sir John Morris (Aberavon) and Richard Livesey (Brecon and Radnorshire), were last week named as peers in the pre-election Honours' list.
Barry Jones leaves Westminster after more than 30 years, including a spell as Shadow Welsh Secretary in the 1980s.
A former chairman of the Welsh Grand Committee, he controversially announced shortly before the election that he was leaving the Commons.
Former Attorney-General Sir John Morris was Wales's longest-serving MP, first elected in 1959.
He was a minister in Harold Wilson's Governments in the 1960s, and joined the Cabinet as Welsh Secretary in 1974.
Richard Livsey is retiring leader of the Welsh Liberal Democrats.
He first became MP for Brecon and Radnor at the 1985 by-election, and retained the seat by just 56 votes at the 1987 general election.
But he lost it to the Conservatives by only 130 votes next time round, only to regain it with a healthy 5,000 majority in 1997.
Former Plaid Cymru president Dafydd Wigley has left Westminster to concentrate on his role as Plaid Cymru AM for Caernarfon.
He first went to the Commons in 1974, and was party president from 1981-4 and again from 1991-2000.
Another former Welsh Secretary, Caerphilly's Ron Davies, is also leaving the Commons for the National Assembly.
He became Welsh Secretary in 1997, and the prospective leader of the Assembly the following year, until he resigned both posts after his "moment of madness" on Clapham Common in October 1998.
Rhodri Morgan became Labour First Minister of the National Assembly in February last year.
in the Assembly he represents Cardiff West, the seat for which he had been MP since 1987.
Merthyr Tydfil and Rhymney representative Ted Rowlands was one of the youngest MPs when he was returned for Labour in Cardiff North in 1966 at the age of 26.
He lost the seat, but became MP for Merthyr at a by-election in 1972.
He was a minister in the Welsh Office and Foreign Office in the Wilson and Callaghan Governments.
Allan Rogers became MP for the Rhondda in 1983, having already been the Euro-MP for South-East Wales since 1979.
A former geologist and teacher, he spoke for Labour in the Commons on defence and foreign affairs.
John Marek had represented Wrexham for Labour since 1983 but will now concentrate on his duties as AM for Wrexham.
He is deputy presiding officer in the Welsh Assembly.
Ynys Mon's MP Ieuan Wyn Jones replaced Dafydd Wigley as Plaid Cymru president last August.
He became MP for Ynys Mon in 1987 but now is another MP giving up his Commons seat for his role as an AM, also for Ynys Mon.