Clyde boss Graham Roberts gave himself a selection headache after resting players ahead of their Scottish Cup replay - and the new bosy ran riot.
Striker Roddy Hunter tapped in the first of his four goals and headed his second two minutes later.
Romauld Bouadji converted Steven Masterton's 35-yard free-kick.
And Hunter hooked home from a corner and added his fourth with a low shot after Stranraer keeper Barry John Corr saved Michael McGowan's spot-kick.
Stranraer: Corr, Swift, Keddie, Dowie, Henderson, Gilfillan (Aitken 46), Hamilton, Martin (Sharp 46), Walker, Hinds (Payne 67), Higgins.
Subs Not Used: Maisano, Morrison.
Booked: Higgins, Henderson.
Clyde: Jarvie, Bouadji, Harris, Higgins, McDonald (Bryson 63), McHale, Masterton (Dick 53), Hunter, Imrie, Arbuckle, McGowan (Tom Brighton 76).
Subs Not Used: McKeown, Cherrie.
Goals: Hunter 3, 5, Bouadji 29, Hunter 32, 83.
Ref: C Hardie