The islands sent only one athlete to the 1998 Games - Ian Godwin.
He travelled with his coach Lonzo Wilkinson and ran in the 800m and 1500m.
Manchester will be the fifth time they have competed at the Games, their first coming in 1978, and they await their first medal.
Did you know?
Netball has come a long way in Nevis since the first association was formed in 1972.
The islands are now a force to be reckoned with at international level but, in the West Indies netball tournament held that year, they suffered a record 117-0 defeat at the hands of Trinidad.