نظام الكيتو الغذائي: ما هو وما مدى فاعليته لانقاص الوزن؟ - منصة شفاء
نظام الكيتو دايت أو حمية الكيتو أو النظام الغذائي الكيتون (The Ketogenic Diet) هو نظام غذائي منخفض الكربوهيدرات مقابل مستوى أعلى من الدهون. يدفع ...
Dec 21, 2022
دراسة
يساعد نظام الكيتو أو الكيتو دايت في فقدان الوزن، فهو النظام الغذائي المحفز على تقليل الشهية من خلال تقليل مستويات الهرمونات المسببة للجوع، والمساعد على زيادة عملية التمثيل الغذائي التي تعمل على تحويل الأطعمة والمشروبات إلى طاقة. وقد أثبتت <anchor>دراسة</anchor> تأثير الكيتو دايت على فقدان الوزن، بعد ملاحظة أن الأشخاص الذين اتبعوا نظام الكيتو يفقدون حوالي كيلوغرام مقارنة بالأشخاص الذين يتبعون النظام الغذائي قليل الدسم.
Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials - PubMed
Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials - PubMed

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. 2013 Oct;110(7):1178-87.

doi: 10.1017/S0007114513000548.

Epub 2013 May 7.


# Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials

[Nassib Bezerra Bueno](/?term=Bueno+NB&cauthor_id=23651522)[1](#full-view-affiliation-1 "Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alagoas, Campus A. C. Simões, BR 104 Norte, Km 97, 57.072-970 Tabuleiro do Martins, Maceió, AL, Brazil."), [Ingrid Sofia Vieira de Melo](/?term=de+Melo+IS&cauthor_id=23651522), [Suzana Lima de Oliveira](/?term=de+Oliveira+SL&cauthor_id=23651522), [Terezinha da Rocha Ataide](/?term=da+Rocha+Ataide+T&cauthor_id=23651522)




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- 1 Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alagoas, Campus A. C. Simões, BR 104 Norte, Km 97, 57.072-970 Tabuleiro do Martins, Maceió, AL, Brazil.

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# Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials

Nassib Bezerra Bueno et al.
Br J Nutr.2013 Oct.

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. 2013 Oct;110(7):1178-87.

doi: 10.1017/S0007114513000548.

Epub 2013 May 7.


### Authors

[Nassib Bezerra Bueno](/?term=Bueno+NB&cauthor_id=23651522)[1](#short-view-affiliation-1 "Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alagoas, Campus A. C. Simões, BR 104 Norte, Km 97, 57.072-970 Tabuleiro do Martins, Maceió, AL, Brazil."), [Ingrid Sofia Vieira de Melo](/?term=de+Melo+IS&cauthor_id=23651522), [Suzana Lima de Oliveira](/?term=de+Oliveira+SL&cauthor_id=23651522), [Terezinha da Rocha Ataide](/?term=da+Rocha+Ataide+T&cauthor_id=23651522)

### Affiliation

- 1 Laboratório de Nutrição Experimental, Faculdade de Nutrição, Universidade Federal de Alagoas, Campus A. C. Simões, BR 104 Norte, Km 97, 57.072-970 Tabuleiro do Martins, Maceió, AL, Brazil.

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**23651522**
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[10.1017/S0007114513000548](https://doi.org/10.1017/s0007114513000548)

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## Abstract


The role of very-low-carbohydrate ketogenic diets (VLCKD) in the long-term management of obesity is not well established. The present meta-analysis aimed to investigate whether individuals assigned to a VLCKD (i.e. a diet with no more than 50 g carbohydrates/d) achieve better long-term body weight and cardiovascular risk factor management when compared with individuals assigned to a conventional low-fat diet (LFD; i.e. a restricted-energy diet with less than 30% of energy from fat). Through August 2012, MEDLINE, CENTRAL, ScienceDirect,Scopus, LILACS, SciELO, ClinicalTrials.gov and grey literature databases were searched, using no date or language restrictions, for randomised controlled trials that assigned adults to a VLCKD or a LFD, with 12 months or more of follow-up. The primary outcome was bodyweight. The secondary outcomes were TAG, HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), systolic and diastolic blood pressure,glucose, insulin, HbA1c and C-reactive protein levels. A total of thirteen studies met the inclusion/exclusion criteria. In the overall analysis,five outcomes revealed significant results. Individuals assigned to a VLCKD showed decreased body weight (weighted mean difference -0·91 (95% CI -1·65, -0·17) kg, 1415 patients), TAG (weighted mean difference -0·18 (95% CI -0·27, -0·08) mmol/l, 1258 patients)and diastolic blood pressure (weighted mean difference -1·43 (95% CI -2·49, -0·37) mmHg, 1298 patients) while increased HDL-C(weighted mean difference 0·09 (95% CI 0·06, 0·12) mmol/l, 1257 patients) and LDL-C (weighted mean difference 0·12 (95% CI 0·04,0·2) mmol/l, 1255 patients). Individuals assigned to a VLCKD achieve a greater weight loss than those assigned to a LFD in the longterm; hence, a VLCKD may be an alternative tool against obesity.


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## Comment in

- [Low-carbohydrate diets impair flow-mediated dilatation: evidence from a systematic review and meta-analysis.](/23829973/)

Schwingshackl L, Hoffmann G.Schwingshackl L, et al.Br J Nutr. 2013 Sep 14;110(5):969-70. doi: 10.1017/S000711451300216X. Epub 2013 Jul 5.Br J Nutr. 2013.PMID: 23829973No abstract available.


## Similar articles

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Nordmann AJ, Nordmann A, Briel M, Keller U, Yancy WS Jr, Brehm BJ, Bucher HC.Nordmann AJ, et al.Arch Intern Med. 2006 Feb 13;166(3):285-93. doi: 10.1001/archinte.166.3.285.Arch Intern Med. 2006.PMID: 16476868Review.

- [Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials.](/26768850/)

Mansoor N, Vinknes KJ, Veierød MB, Retterstøl K.Mansoor N, et al.Br J Nutr. 2016 Feb 14;115(3):466-79. doi: 10.1017/S0007114515004699.Br J Nutr. 2016.PMID: 26768850

- [Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials.](/32238384/)

Ge L, Sadeghirad B, Ball GDC, da Costa BR, Hitchcock CL, Svendrovski A, Kiflen R, Quadri K, Kwon HY, Karamouzian M, Adams-Webber T, Ahmed W, Damanhoury S, Zeraatkar D, Nikolakopoulou A, Tsuyuki RT, Tian J, Yang K, Guyatt GH, Johnston BC.Ge L, et al.BMJ. 2020 Apr 1;369:m696. doi: 10.1136/bmj.m696.BMJ. 2020.PMID: 32238384Free PMC article.

- [Low-carbohydrate diets impair flow-mediated dilatation: evidence from a systematic review and meta-analysis.](/23829973/)

Schwingshackl L, Hoffmann G.Schwingshackl L, et al.Br J Nutr. 2013 Sep 14;110(5):969-70. doi: 10.1017/S000711451300216X. Epub 2013 Jul 5.Br J Nutr. 2013.PMID: 23829973No abstract available.

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Schwingshackl L, Hoffmann G.Schwingshackl L, et al.J Acad Nutr Diet. 2013 Dec;113(12):1640-61. doi: 10.1016/j.jand.2013.07.010. Epub 2013 Oct 17.J Acad Nutr Diet. 2013.PMID: 24139973Review.


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- [Potential Add-On Benefits of Dietary Intervention in the Treatment of Autosomal Dominant Polycystic Kidney Disease.](/39203719/)

Rosati E, Condello G, Tacente C, Mariani I, Tommolini V, Calvaruso L, Fulignati P, Grandaliano G, Pesce F.Rosati E, et al.Nutrients. 2024 Aug 6;16(16):2582. doi: 10.3390/nu16162582.Nutrients. 2024.PMID: 39203719Free PMC article.Review.

- [Beneficial Effects of the Ketogenic Diet on Nonalcoholic Fatty Liver Disease (NAFLD/MAFLD).](/39200999/)

Dyńka D, Rodzeń Ł, Rodzeń M, Łojko D, Kraszewski S, Ibrahim A, Hussey M, Deptuła A, Grzywacz Ż, Ternianov A, Unwin D.Dyńka D, et al.J Clin Med. 2024 Aug 17;13(16):4857. doi: 10.3390/jcm13164857.J Clin Med. 2024.PMID: 39200999Free PMC article.Review.

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- [Successful Outcome of VASER Liposuction Followed by Keto Diet in a 35-year-old Man with Class III Obesity.](/39185383/)

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