Introduction: Radiotherapy for head and neck cancer can cause severe mucositis (ulcers in the mouth) and pain. Photobiomodulation (Light therapy) will be used before and during radiotherapy to try to reduce the occurence and severity of mucositis in patients treated with radiotherapy for head and neck cancer~Rationale: Previous studies in head and neck cancer patients have shown that photobiomodulation (light therapy) can prevent mucositis. There are currently no centers in Canada using this technique in routine practice, but this is recommended in International guidelines and widely used in Europe. The investigators therefore wish to implement this technique in Ottawa under the umbrella of a clinical trial to insure its safety and efficacy in a Canadian context.~Purpose/Objectives: Primary Objective Primary Objective~• To determine the cumulative incidence of acute mucositis as defined by CTCAE version 2.0 for radiation induced mucositis (Appendix 1) during radiotherapy and for 1month following radiotherapy~Secondary Objectives~To determine the following during radiotherapy and for 24 months post-treatment~Rate of occurrence of acute radiation dermatitis~Pain scores~Opioid use~ESAS scores during and after RT~FACT-HN questionnaire scores~Late subcutaneous neck fibrosis~Late mucosal and skin telangiectasia~Study design/methodology:~This is single arm prospective cohort study of a single intervention (photobiomodulation) in patients with head and neck cancer for the prevention of oral mucositis.~Outcomes will be the following:~Rates of acute and late mucositis according to CTCAE version 2.0~Rates of acute and late dermatitis and fibrosis according to CTCAE version 5.0~Rates of late teleangiectasia~Pain scores as per Edmonton Symptom assessment scale (ESAS) and modified brief pain inventory~Rates of opioid use~FACT-HN scores~EQ5D scores~Anticipated public/scientific benefit:~This study aims to study the use of Photobiomodulation treatments for prevention of oral mucositis. This is recommended in international guidelines but not used in routine practice in Canada. The benefit of this study is to allow implemetation of this technique in the Canadian context in a controlled and evaluated manner. This will hopefully then allow further study and wider implementation of this technique both in Ottawa and in Canada
Radiotherapy for head and neck cancer can cause severe mucositis (ulcers in the mouth) and pain. Photobiomodulation (Light therapy) will be used before and during radiotherapy to try to reduce the occurence and severity of mucositis in patients treated with radiotherapy for head and neck cancer~Previous studies in head and neck cancer patients have shown that photobiomodulation (light therapy) can prevent mucositis. There are currently no centers in Canada using this technique in routine practice, but this is recommended in International guidelines and widely used in Europe. The investigators therefore wish to implement this technique in Ottawa under the umbrella of a clinical trial to insure its safety and efficacy in a Canadian context.