Primary Objectives:~To assess the D1 receptor occupancy (D1 RO) in striatum after a single oral administration of PF-06412562~To assess the relationship of D1 RO in the striatum versus plasma exposure of PF-06412562 after a single oral administration.~Secondary Objective:~• To evaluate the plasma exposure of PF-06412562for the duration of PET scan following a single oral administration of PF-06412562.~Safety Objectives:~• To evaluate the safety and tolerability of PF-06412562 of single oral doses of PF-06412562.
To assess the D1 receptor occupancy (D1 RO) in striatum after a single oral administration of PF-06412562.