This study will evaluate:~The safety and tolerability of a single dose of VGX-1027 as determined by: adverse event reporting, clinical laboratory results, vital signs, physical examinations, and electrocardiograms (ECGs).~The pharmacokinetic (PK) profile of VGX-1027 maximum concentration (Cmax)
To assess the safety and tolerability of a single dose of VGX-1027 in the range of 1-800mg.