Objectives:~To evaluate the safety and tolerability profile of multiple oral ascending dose levels of BPN14770 in healthy young and elderly subjects.~To characterize the plasma pharmacokinetic profile of BPN14770 following oral administration in healthy young and elderly subjects.~To provide preliminary assessment of the cognitive effect of BPN14770 in healthy elderly subjects.
This is a randomized, double-blind (Investigator and subject-blinded) placebo-controlled, multiple, ascending-dose study to evaluate the safety, tolerability, and pharmacokinetic profile of BPN14770 in healthy young and elderly male and female subjects and to provide a preliminary assessment of the cognitive effects of BPN14770 in healthy elderly subjects.