This is four arm study. Approximately 480 (120 per group) would need to complete the 6 weeks of treatments.~In order to achieve that number of subjects, approximately 700 subjects will be screened randomized into the study.~A screening visit (Visit 1) will be inclusive of at least the 2-week (14 days) placebo Run-in Period during which asthma subjects will wash out their daily inhaled corticosteroid and other medications and assessed for compliance. Study treatment period will be for a duration of 6 weeks with visits: Visit 2 - Baseline Day 1; Visit 3 Day 21 (± 2 days) and Visit 4 Day 42 (± 2 days). Rescue Therapy: Short-acting beta agonists, Albuterol 90 μg/actuation
Approximately 480 (120 per group) would need to complete the 6 weeks of treatments.