Aim of this study is the clinical evaluation of an image-guided adaptive radiotherapy (ART) concept. This involves the adaption of the radiotherapy treatment plan according to changes in tissues and variations in patients position and posture during a radiotherapy treatment course, based on repeat CT scans.~It is prospectively investigated, if dosimetric improvements can be achieved using this approach and if the method using the software-package ReDeform can be implemented in clinical Routine. For that purpose 2 repeat CT scans are acquired during the radiotherapy course (week 3 and week 5 of radiotherapy). The Initial CT scan is matched to the follow-up CT-scan by means of deformable image registration.
Aim of this study is the clinical evaluation of an image-guided adaptive radiotherapy concept. This involves the adaption of the radiotherapy treatment plan according to changes in tissues and variations in patients position and posture during a radiotherapy treatment course, based on repeat CT scans.~It is investigated, if dosimetric improvements can be achieved using this approach and if the method using the software-package ReDeform can be implemented in clinical Routine.