Objectives:~Secondary objectives are to investigate the effects of wakame and spirulina consumption on fasting markers for lipid metabolism, glucose metabolism and blood pressure.~Study design:~This study is a double-blinded, randomized, placebo-controlled, crossover intervention trial consisting of three intervention periods of 17 days each, separated by a minimum washout period of 14 days.~Study population:~The study population will consist of 37 healthy, non-hypercholesterolemic men and women aged between 18 and 70 years.~Intervention:~All subjects will receive wakame, spirulina and placebo capsules in randomized order. Subjects will be asked to consume 12 capsules per day for 17 days, which is equal to 4.8 grams of wakame or spirulina a day.
The primary objective of this study is to investigate the effects of wakame and spirulina consumption on intestinal cholesterol absorption.