The standard treatment of patients with chronic hepatitis C infection (HCV) is treatment with ribavirin. Actually, the compliance (2x daily) seems to be a problem. To increase patients' compliance, it is investigated if the total dose of ribavirin can be taken once daily.~The pharmacokinetics of ribavirin at different dosage regimes is investigated.
The purpose of this study is to determine if the medicines for chronic hepatitis C can be taken once daily, instead of twice daily.