To establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer~Recruiting 30 patients with prostate cancer ahead to radical prostatectomy~PET/MR using 18F-choline with dedicated prostate MRI in all patients~PET/MR using 18fluoride(F)-fluorodeoxyglucose(FDG)in all patients after 2-7 days~PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR~outcome assessment: comparison of scan time, image quality, tumor detection rate, standardized uptake values of lesions~establishing optimal imaging technique for prostate PET/MR~To establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer~comparison of findings on PET/MR, MRI and PET/CT with pathological mapping after radical prostatectomy~outcome assessment: accuracy of PET/MR for localization and staging of prostate cancer compared with MRI only and PET/CT only~To establish the imaging biomarker using PET/MR for early detection of recurrent prostate cancer~Recruiting 15 patients with recurrent prostate cancer treated by surgery, hormone, or radiation therapy~Recruiting 15 patients with treated prostate cancer without recurrence~PET/MR using 18F-choline with dedicated prostate MRI in all patients~PET/MR using 18F-FDG in all patients after 2-7 days~PET/CT using 18F-FDG in all patient immediate after 18F-FDG PET/MR~comparison of findings on PET/MR, MRI, and PET/CT with clinical data in two patient groups with or without recurrent prostate cancer~outcome assessment: accuracy of PET/MR for early detection and localization of recurrent prostate cancer compared with MRI only and PET/CT only
To development of clinical assessment technique using multi-radiotracer positron emission tomography/magnetic resonance (PET/MR) in prostate cancer~to establish the optimal imaging technique of PET/MR using multiple radioactive tracers for prostate cancer~to establish the imaging biomarker using PET/MR for clinical assessment of prostate cancer and early detection of recurrent prostate cancer