Additional Study Purpose Details: Investigation of the pharmacokinetics, safety, and tolerability of a single dose of PD 0332334 in patients with impaired renal function.~On February 23rd 2009, a decision to terminate further development for PD 0332334 was communicated to investigators in this study. The decision to terminate this study was not based on any safety concerns.
To investigate the effect of kidney function on the elimination of a single dose of PD 0332334 from the body.~To investigate the safety and tolerability of a single dose of PD 0332334 in patients with impaired kidney function.