This observational, retrospective, propensity-score matched cohort study using the Manitoba Immunization Monitoring System (MIMS) and the hospital, physician, and prescription claims databases of the Manitoba Health (MH) Database System will assess if Arepanrix™ vaccination during the 2009 pandemic was associated with an increased risk of multiple sclerosis (MS) and other demyelinating conditions not ultimately leading to a multiple sclerosis diagnosis in Manitoba, Canada.~The data will be collected form the following linked databases:~Manitoba Health (MH) administrative databases~Manitoba Immunization Monitoring System (MIMS)~Manitoba Health Population Registry (MHPR)~Drug Program Information Network (DPIN)~Hospital Abstract Database~The Medical Services database
The purpose of this database study is to assess if Arepanrix™ vaccination during the 2009 pandemic was associated with an increased risk of multiple sclerosis (MS) in Manitoba, Canada.