We test the effectiveness of an homeopathic drug versus placebo and a temporal control group (patient with no add-on treatment) following orthopedic knee surgery.~All patients have a PCA of morphine for 24 hours after surgery. After this period they can take an oral tablet of morphine on request.~Group A: Patients with study treatment (homeopathy) allocation. Double blind group with 70 patients~Group B: Patients with placebo allocation. Double blind group with 70 patients~Group C: Temporal control group with patients who take only the morphine. Open group with 25 patients~The total power: 70 +70 + 25 = 165 patients~Main Objective:~To assess the effect of homeopathy in terms of morphine consumption delivered by PCA (patient control analgesia) for 24 hours after a knee ligamentoplasty.~Secondary Objectives:~To assess the effect of homeopathy in terms of total morphine consumption between H24 and H72 after a knee ligamentoplasty.~To assess the effect of homeopathy on the pain perception using a analogical visual scale for 72 hours.~To asses the placebo effect of the homeopathic treatment.~Main Assessment Criterion:~Morphine consumption delivered by PCA between 0 and 24 hours after knee ligamentoplasty~Secondary Assessment Criteria:~Morphine consumption between 0 and 72 hours after ligamentoplasty~Pain assessment at H0, H4, H24 and H72 using 10 cm Analogical Visual Scale~Inclusion Criteria:~age ranging from 18 to 60.~patients candidates for a ligamentoplasty of the anterior cruciate ligament.~Exclusion Criteria:~patient with corticoid and immunodepressor treatment
This is an add-on, double blind, and randomised clinical trial with three groups: a homeopathic group, a placebo group, and a temporal control group.~The aim of this trial is to assess the effect of homeopathy on the consumption of morphine delivered by PCA (patient control analgesia) for 24 hours after a knee ligamentoplasty.