The primary objective of this study is as follows:~• To evaluate the effect of steady-state ranolazine on the steady state PK of metformin in subjects with T2DM.~The secondary objectives of this study are as follows:~To examine the safety and tolerability of metformin when co administered with ranolazine at steady-state in subjects with T2DM.~To determine the steady-state PK of ranolazine in subjects with T2DM receiving metformin.
The purpose of this study is to evaluate the effect of steady-state ranolazine on the steady state PK of metformin in subjects with type 2 diabetes mellitus (T2DM).