In this prospective observational study the investigators will report on 20 male subjects with proven WHO-classification Zika infection. These subjects will be followed up for a maximum of 12 months to observe the presence, viral load and infectivity of Zika virus (ZIKV) in semen over time.~Knowledge of the possible presence, infectivity and persistence of ZIKV in semen will provide evidence-based data for~estimating of the risk of sexual transmission of ZIKV in the general population~antenatal guidelines for the prevention of sexual transmission of ZIKV to the fetus~advising couples on the length of time that pregnancy should be avoided in women wishing to conceive after their partner's ZIKV infection~strategies to prevent transmission of ZIKV infection through assisted reproductive treatment (ART)~advice on gamete cryopreservation~optimising investigations for diagnosis of ZIKV in males.
In this prospective observational study the investigators will report on 20 male subjects with proven WHO-classification Zika infection. These subjects will be followed up for a maximum of 12 months to observe the presence, viral load and infectivity of Zika virus (ZIKV) in semen over time.