This is a phase I, single-center, open-label, two-treatment, food-effect, randomized study in 40 healthy Caucasian male subjects in order to determine the impact of the food on the absorption of the ABX464.~The two different treatments are the followings:~Treatment A = 50mg of ABX464 (two 25mg capsules) /Fasted~Treatment B = 50mg of ABX464 (two 25mg capsules) / Fed~This study consists of two groups:~Group 1 - single dose assessments, two-period, two-treatment, cross-over: 20 subjects will receive a single dose of 50mg of ABX464 in fed and fasted condition, separated by a wash-out period of at least 45 days.~Group 2 - multiple dose assessments: 20 subjects will receive 50mg of ABX464 every 3 days during 10 days in fasted or fed condition.
The goal of this study is to determine the impact of the food on the absorption of the ABX464.