We will prospectively assess the utilization of Desmopressin in improving nocturnal enuresis in patients after radical cystectomy with orthotopic bladder reconstruction.~Patients after radical cystectomy with neobladder reconstruction will be given Desmopressin 0.1 mg once a day for a duration of one month.~Before beginning treatment patients will be given the NNES-Q questionnaire to assess severity of nocturnal enuresis.~At the end of treatment, the same questionnaire will be given to all patients to assess if nocturnal enuresis improved.~Sodium levels will be tested before treatment, 2 weeks after beginning treatment and at the end of treatment.
The purpose of this study is to prospectively assess whether Desmopressin, given for a period of month to patients after radical cystectomy with orthotopic bladder reconstruction, improves and lowers the rate of nocturnal enuresis.