• Patients will be divided into two groups 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby The 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby plus 400 microgram misoprostol rectally with catheterization and another 400 microgram rectally after closure of abdomen~Then we will compare between two groups regarding~Intaoperative blood loss~Risk of Postpartum hemorraghe in the first 24 hrs~HB pre and postoperative for all patients~Intraoperative blood loss will be estimated by the number and weight of soaked towels and amount of blood in suction unit
• Patients will be divided into two groups 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby The 100 patients will receive routine ecbolics (for example oxytocin) after delivery of baby plus 400 microgram misoprostol rectally with catheterization and another 400 microgram rectally after closure of abdomen~Then we will compare between two groups regarding~Intaoperative blood loss~Risk of Postpartum hemorraghe in the first 24 hrs~HB pre and postoperative for all patients~Intraoperative blood loss will be estimated by the number and weight of soaked towels and amount of blood in suction unit