To perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED. The 4 groups are as follows:~Oxycodone/acetaminophen (5/325)~Hydrocodone/acetaminophen (5/325)~Codeine/acetaminophen (30/300)~Ibuprofen/acetaminophen (400/1000)
The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.