Cleanoze® consists of a powder made up of Sodium chloride and Sodium Bicarbonate. This powder when dissolved in 250 ml of water is closely resembles the content of a body fluid which normally baths the outside of the cells of the body. This fluid is isotonic solution.~The nasal saline irrigation is the common procedure for upper respiratory tract infection patients including chronic rhinitis. The physician usually order the normal saline with appropriate medication e.g. anti-histamines, nasal steroids and anti-biotics to treat this condition.~The investigators proposed that the Cleanoze® is superior to the traditional nasal saline irrigation in term of the ease of use which will resulting in a better quality of life of the participants. This study will compared the efficacy, adverse reactions, complications and ease of use of Cleanoze® comparing with normal saline solution.~Study Population: Any patients with chronic rhinitis (e.g. allergic rhinitis, vasomotor rhinitis) will be randomized to receive the study or control medication. The investigators will include the children 5 years and above which able to doing the lavage under the parents assistant or by them self.~Study Design: Phase III randomized controlled trial~Sample Size: Estimate from pilot study, the 71 patients per arm was estimated (142 participants totally).~Study Duration:~Duration of enrollment is 1 year.~The patients will be followed up to 1 months depend on the disease conditions.~The data analysis will take 3 additional months~The full report will complete after the data analysis within 3 months~The total of 1 year and 6 months period needed for this study.~Primary Objective: To compare the satisfaction of the patients using Cleanoze® versus conventional device~Secondary Objective(s):~The adherence to Cleanoze® device~The durability of the Cleanoze® device~The patient symptom score (VAS)~The SNOT-22 questionaire for evaluating the quality of life of the patients
The investigators proposed that the Cleanoze® is superior to the traditional nasal saline irrigation in term of the ease of use which will resulting in a better quality of life of the participants. This study will compared the efficacy, adverse reactions, complications and ease of use of Cleanoze® comparing with normal saline solution