In the study NextGen SE (single-center, prospective, open diagnostic study) are on-hand a cohort comprising each 50 pediatric and 50 adult patients, and in which there are an unclear movement disorder or an unclear cognitive disorder, examines the following questions:~Primary:~Number of diagnoses made by next-generation sequencing (NGS)~Secondary:~Restriction of the quality of life by unclear disease~Cost of not purposeful preliminary diagnostics (beyond the minimal diagnostic data of the diagnosis to therapy and follow-up examinations~Time to diagnosis
In the study, NextGen SE are on-hand a cohort comprising each 50 pediatric and 50 adult patients, and in which there are an unclear movement disorder or an unclear cognitive disorder, examines the following questions :~Primary:~Number of diagnoses made by NGS~Secondary:~restriction of the quality of life by unclear disease~Cost of not purposeful preliminary diagnostics ( beyond the minimal diagnostic data set )~Impact of the diagnosis to therapy and follow-up examinations~Time to diagnosis