This is a single-centre, placebo-controlled, randomised, double-blind study involving SAD and MAD of ASLAN003 in healthy subjects.~The study is divided into two parts:~Part A: SAD cohorts and 1 cohort to assess food effect of ASLAN003 PK.~Part B: MAD cohorts with one cohort being of healthy elderly subjects.~There will be a sentinel pair of subjects for each of SAD Cohorts 1, 2 and 3 who will be dosed first and then the same dose will be given to the rest of the subjects in the respective cohorts.~In addition, 8 subjects will receive ASLAN003 under both fed and fasted conditions
This is a single-centre, placebo-controlled, randomised, double-blind study to evaluate the safety and tolerability of single ascending doses (SAD) and multiple ascending doses (MAD) of ASLAN003 in healthy subjects