The PHP study aims to delineate gene products involved in high on-treatment platelet reactivity in aspirin-treated cardiovascular patients using a system biology approach that include proteomics analysis of selected platelet sub-fractions in patients displaying extreme phenotype.~Main objective:~to characterize the proteome profile of platelet hyperreactivity in aspirin-treated cardiovascular patients~Secondary objectives:~to characterize the platelet hyperreactivity phenotype in cardiovascular patients treated with aspirin~to determine genetic polymorphisms associated with platelet hyperreactivity
The PHP study aims to delineate gene products involved in high on-treatment platelet reactivity in aspirin-treated cardiovascular patients.