)Determine the change in symptomatology and function in refractory bipolar depression, when treated with combination of DEP+AZP for a period of 12 weeks~2) Determine the tolerability and safety of AZP added to DEP in the treatment of refractory bipolar depression
Determine the change in symptomatology and function in refractory bipolar depression, when treated with combination of DEP+AZP for a period of 12 weeks~Determine the tolerability and safety of AZP added to DEP in the treatment of refractory bipolar depression