This is a prospective, randomized, double-blind, double-dummy and placebo-controlled study in individuals with disabling migraine. The participants will be randomized to receive Rizatriptan + Naproxen (10/550mg), Rizatriptan (10mg), Naproxen (550mg) or placebo.~⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is outside brazil).
A phase III study, multicenter, double-blind, double-dummy, randomized, single-dose, placebo-controlled study to evaluate the efficacy and safety of Rizatriptan-Naproxen (10/550 mg) in the acute treatment of migraine.~⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is outside brazil).