In this study, patients being treated with Negative Pressure Wound Therapy (NPWT) will be randomized to receive either:~Oasis® matrix, applied to the wound, along with standard of care including NPWT OR~Standard foam, applied to the wound prior to activation of NPWT, which is standard care.~Wounds will be examined weekly for up to 12 weeks. At weeks 4, 8, and 12, the NPWT evacuation canister will be collected for specimen analysis.~The aim of this study is to determine the therapeutic effect of using Oasis® Wound Matrix with NPWT. Outcomes include: a) closure rate of non-healing wounds, and b) levels of growth factors and interleukins in fluid evacuated from the wound.
This study evaluates the therapeutic effect of Oasis® Matrix along with Negative Pressure Wound Therapy (NPWT) on pressure wounds. Either Oasis or standard foam will be applied to the wound prior to activating the NPWT.