This study is an open-label, randomized, single dose, four period, balanced crossover study to assess in eligible healthy male or female subjects:~The relative bioavailability of the wet milled GSK1322322 tablet formulation with and without food compared to an oral mesylate salt solution.~The effect of body weight on the pharmacokinetics of GSK1322322 when given either orally or IV.~The absolute bioavailability of the wet milled tablet and the oral mesylate salt solution compared to the IV formulation.
This study is an open-label, randomized, single dose, four period, balanced crossover study to assess in eligible healthy male or female subjects.