Will meet the inclusion criteria of patients with unresectable esophageal squamous cell carcinoma, divided into 2 groups randomly:~Experimental group: radiotherapy combined with S-1 chemotherapy;~control group: radiotherapy combined with S-1 chemotherapy for first to 14 days and 29 ~ 42 days, plus cisplatin first 1~ 4 days and 29 ~ 33 days. Using IMRT radiotherapy.~Two weeks after radiotherapy finish, two cycle adjuvant chemotherapy with S-1 70 mg/m2 1~ 14 days, or S-1 70 mg/m2 1~ 14 days, plus cisplatin 25mg/m2 1~ 4 days, 21 days for a cycle.~Primary Outcome Measure is complete remission rate.~Secondary Outcome Measures are overall survival (OS) and Progression-Free-Survival (PFS) and toxicity.
Will meet the inclusion criteria of patients with esophageal squamous cell carcinoma, divided into 2 groups randomly:~Experimental group: radiotherapy combined with S-1 chemotherapy.~Control group: radiotherapy combined with S-1 chemotherapy and cisplatin.