Background:~Patients with non-ST elevation myocardial infarction (non-STEMI), as compared with STEMI patients, have a higher risk profile, more often MVD and less favourable outcome. Recent studies showed that complete revascularization in STEMI patients is feasible and effective. However, there is no clear evidence regarding the role of complete coronary revascularization by PCI in patients with non-STEMI with MVD.~Objective:~To compare FFR guided complete revascularization during the index procedure with usual care in non-STEMI patients with multivessel disease.~Design:~Prospective, multicentre, 1:1 randomized, investigator initiated study.~Hypothesis:~FFR guided complete percutaneous revascularisation of all significant stenosis in the non-culprit lesion performed within the index PCI procedure will improve clinical outcomes compared to the usual care, guided by discretion of the physician.
To compare FFR guided complete revascularization during the index procedure with usual care in non-STEMI patients with multivessel disease.