The investigators will recruit adults patients with type 2 diabetes aged over 20 years with spot urine albumin to creatinine ratio over 30mg/g in two consecutive measurements.~Enrolled patients will be randomly assigned to receive pentoxifylline (400mg three times daily) or placebo for 24 weeks.~Fasting blood and spot urine will be collected at baseline, 12 weeks and 24 weeks.~The investigators will evaluate the impact of pentoxifylline on proteinuria in type 2 diabetic patients.
This multi-center, randomized controlled study aims to evaluate the effects of pentoxifylline on proteinuria in Korean type 2 diabetic patients.