Photorefractive Keratectomy (PRK) is a common elective surgery used to correct refractive errors. We propose that amniotic fluid drops may be beneficial in promoting ocular surface healing following PRK. Purified amniotic fluid (pAF) contains anti-inflammatory, anti-microbial and regenerative factors similar to solid amniotic membrane. Individual patients will be randomized to one of two post-operative drop regimens, control eyes that will receive placebo saline solution (NaCl 0.9%, Baxter Medical), and study eyes that will receive pAF four times daily for seven days.~This is a randomized, double-masked, placebo-controlled study to determine~the safety of pAF in patients who undergo PRK~if pAF hastens re-epithelialization following PRK compared to placebo~if pAF reduces post-operative pain following PRK compared to placebo~if pAF affects visual outcome following PRK compared to placebo~if pAF affects ocular surface staining and corneal regularity following PRK compared to placebo
This is a randomized, double-masked, placebo-controlled study to determine the safety of pAF in patients who undergo PRK.