A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.~The specific objectives of the Drug Utilization Study are:~To estimate trends by month in the number of prescriptions for a one-year period before, and each month after, the implementation of the REMS~To compare average number of prescriptions per 3 month (quarter) period in the 2 years before as compared to the same measure during Implementation and the Active Period~To evaluate change by patient characteristics (age group, gender, pay type, prescriber specialty)~To compare the trends in prescribing, both number of prescriptions and patients, by prescriber specialty~These trends and changes over time will be estimated for the following groups of opioids:~ER/LA opioids included in the class REMS~Comparator products/classes~Immediate release (IR) opioids~Celecoxib~Benzodiazepines~To show switches (absolute and rates of switching) from ER/LA opioids to comparator analgesics (IR opioids or celecoxib) with introduction of REMS
A drug utilization study will be performed to describe trends in the number of prescriptions and patients for class REMS ER/LA opioids and comparator products.