The optimal treatment for PCV is still under debate. Little knowledge is known about the treatment effect of 1+pro re nata(PRN) treatment regimen for PCV. The aim of this study is to compare the outcomes of different treatment methods including PDT, IVR and combination therapy under the 1+PRN treatment regimen for PCV.~The study is the first prospective randomized controlled trial about different treatment methods on PCV under 1+PRN treatment regimen. The null hypothesis of the study is that combination therapy may be the optimal treatment method for PCV. The primary outcome measures is the Best-corrected visual acuity (BCVA) of the participants at 1 year after treatment. Besides, the slit-lamp examination, tonometry, funduscopy, and OCT, FFA, ICGA examinations will also be compared between different groups to find the optimal treatment for PCV.
The aim of this study is to compare the outcomes of different treatment methods including photodynamic therapy (PDT), intravitreal ranibizumab injection (IVR) and combination therapy under the 1+PRN treatment regimen for polypoidal choroidal vasculopathy (PCV) and find the optimal treatment for PCV.