Aim1: To evaluate the safety and tolerability of three different lactoferrin doses in preterm infants~Lactoferrin related adverse events and serious adverse events~Number of infants reaching full feeds while receiving lactoferrin (120 ml/kg/day)~Episodes of not receiving enteral feedings for > 24 hours once feeding is initiated~Aim 2: To evaluate lactoferrin absorption and excretion.~Examine lactoferrin levels in saliva, urine, plasma and stool~Examine lactoferrin levels in maternal and human donor milk.~Aim 3: To evaluate the effect of lactoferrin on the intestinal microbiome structure.
To evaluate the safety and tolerability of three different lactoferrin doses in preterm infants