The main objective of the study is to understand the influence of nutrition and dietary patterns on microbiome and bone trajectories during early life. Specific research objectives are:~Establish the reference trajectories of gut microbiome maturation index and bone development in healthy Chinese children aged 0-3years~Assess the impact of early life nutrition on gut microbiome trajectory~Investigate the influence of microbiome, early life parameters and nutritional parameters on bone health
The aim of the study is to establish the longitudinal microbiome and bone trajectories from birth to 3 years, and to evaluate the influence of nutrition on these trajectories.