In this prospective randomized controlled trial patients with previous breast cancer will be randomized into two treatment arms:~Control Group of Usual Physical Activity~Intervention Group of Increased Physical Activity~No specific intervention will be performed In the patients randomized in the control group.~Patients randomized in the Intervention Group will receive a program of increased physical activity starting from 5000 steps/day up to 12000 steps/day after 8 weeks. At the same time patients of this group will receive an 8-week recreational program of brisk walking/running (3 times a week).~All the patients enrolled in this trial will receive a pedometer device (Garmin Vìvofit) able to count the number of steps, determine a daily goal of steps, determine the covered distance (in Km), determine daily caloric consumption, and determine the movements during sleep.~Data will be downloaded in a specific application available online (Garmin Connect).~All the patients will receive written information on the potential benefits of physical exercise and better lifestyle.~At baseline, at the end of the study period (8 weeks) and after 1 year patients will be asked to fill out the following questionnaires:~Funcional Assessment of Cancer Therapy- Breast (FACT-B, 37 items)~Patient reported symptoms (PRS like International Breast Cancer Study Group form, 19 items)~Funcional Assessment of Cancer Therapy- Fatigue (FACT-Fatigue, 13 items)~Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog; 37 items)~Impact of Event Scale (IES; 22 items)~At baseline, at the end of the study period (8 weeks) patients will be asked to undergo blood draw for serum analysis of insulin, IGF-1, leptin, PCR, cholesterol, triglycerides leucocyte count, T lymphocyte subpopulations (T regulatory and TH17).~The hypothesis of the study is that even a short course of increased physical activity may improve quality of life of non-regular exercisers women with a personal history of breast cancer who completed treatment (endocrine treatment excluded).
This is a prospective randomized controlled trial in which patients with previous breast cancer will be randomized into two treatment arms:~Control Group of Usual Physical Activity~Intervention Group of Increased Physical Activity~No specific intervention will be performed In the patients randomized in the control group.~Patients randomized in the Intervention group will receive a program of increased physical activity starting from 5000 steps/day up to 12000 steps/day after 8 weeks. At the same time patients of this group will receive an 8-week recreational program of brisk walking/running (3 times a week).~All the patients enrolled in this trial will receive a pedometer device (Garmin Vìvofit) able to count the number of steps, determine a daily goal of steps, determine the covered distance (in Km), determine daily caloric consumption, and determine the movements during sleep.