Several papers suggest that inflammation is able to induces both headache and low levels of vitamin D. However, to date a correlation between plasma vitamin D levels and headache has not been demonstrated. Recently we documented that low levels of Vitamin D are related to a low statin efficacy. In this study we will evaluate the plasma levels of vitamin D in patients with headache admitted to the Center of Headache of Pugliese Ciaccio Hospital.~Moreover it will be also evaluated:~the correlation between efficacy and safety of drugs used in headache treatment and plasma vitamin D levels.~the role of vitamin D supplementation on both headache symptoms and drug effects.~Plasma vitamin D levels in patients with headache will be evaluated respect to patients without headache.
To date there are conflicting data concerning a correlation between plasma vitamin D levels and headache.~The aim of this study was to evaluate plasma vitamin D levels in patients with headache admitted to the Center of Headache of Pugliese Ciaccio Hospital.