This is an open-label, non-randomized Phase II study, planning to recruit about ten patients.~The primary objective of this study is to investigate the safety of MRI-guided LITT in combination with the early application of temozolomide.~The secondary outcome is to explore the efficacy of MRI-guided LITT combined with the early use of temozolomide in treating recurrent glioblastomas.
This study aims to investigate the safety and efficacy of Laser Interstitial Thermal Therapy (LITT) combined with postoperative early use of temozolomide in treating recurrent glioblastomas.