60 patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 30) , and the paravertebral group (group P, n =30)~All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving GA~Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic.~Random numbers were generated using a computer-generated randomization code and were sealed in an opaque envelope. Randomization was conducted by a person who was not involved in the study.~An independent observer who was blind to the group assignment checked the intraoperative and postoperative data.~VAS pain score immediately postoperative and at 2,4,6, 8,12,18,24,36 ,48hrs.postoperative.
All patients admitted in National Cancer institute, Cairo University for breast surgeries will be investigated for inclusion criteria in the current study. And will be enrolled if fulfilled the criteria into 2 groups~60 patients will be included in this prospective randomized study. The patients will be allocated into two groups: the ESPB group (group E, n = 30) , and the paravertebral group (group P, n =30)~All patients will do Ultrasound-guided ESPB for group E and PVB for group P before receiving general anesthesia~Postoperatively Patients in both groups will receive intravenous morphine 3 mg as rescue analgesic