The present study is a double-blinded randomized clinical trial with a duration of 28 days.~80 orally and systemically healthy participant will be allocated in the test (probiotic) and the control (placebo) group at baseline.~The intervention is sugar stress, which will be applied at baseline and continue through day 14, followed by 14 days without sugar stress.~Clinical measurements and sampling will be performed at baseline, day 14 and day 28~Primary endpoint: Changes in microbial composition.~Secondary endpoints: Changes in clinical and immunological parameters
The present study is a double-blinded randomized clinical trial with a duration of 28 days.