Purpose: The purpose of the study is to evaluate the MDoloris ANI monitor as an effective tool for objectively measuring perioperative stress, and as a prediction of post-operative pain.~Hypothesis: High perioperative anxiety scores, high post-operative pain scores, high post-operative anesthetic dosing, and high incidence of provider intervention will be positively correlated with frequency and magnitude of changes in the ANI score.~Justification: Anesthetists are constantly monitoring a patient's heart rate during caesarean sections. This is standard care, and this monitoring provides useful information about a patient's level of sedation, analgesia, and comfort. The ANI monitor takes more heart rate information through two electrodes placed on a patient's chest, and non-invasively provides more information by which anesthetists can improve the patient's standard of care.~Primary Objective: To determine whether the ANI monitor is a viable means of measuring perioperative anxiety during C-sections.~Secondary Objectives:~To determine if the ANI monitor is capable of providing anesthetists with an objective prediction variable for post-operative pain.~Research Methods and Design: Once eligibility is determined , the patient will be approached in the pre-operative waiting area at a time determined by the charge nurse. If they consent to the study, they will be given an validated questionnaire which assesses the patient's level of operative stress. After the survey, they will have the ANI electrodes placed on their chest by a member of the study team. The collection of this pre-surgical data provides the research team with a baseline to which they will compare the operative and post-operative results. Five to ten minutes prior to their surgery, the electrodes will be removed, and the monitor will be brought to the OR. The monitor will be plugged in to an electrical socket far away from areas of high traffic, and will not disturb the flow of OR staff.~During the operation, a member of the study team will constantly watch the ANI monitor to check for optimal connectivity, and will record the events of surgery. A record of the events is critical to interpreting the meaning of the ANI score, as it allows the team to match distinct stimuli with the number produced by the monitor.~The spinal block typically wears off after 24 hours, so at 24- and 48 hours following the c-section, a study team member will approach the patient on the wards, and ask for their resting, and evoked pain scores on a VAS 0-100 mm scale. Evoked pain is pain caused by movement. The investigators have chosen the previously used metric of a change in position: from lying to sitting. If the patient has received drugs for pain already, the investigator will ask them to score the pain they experienced before receiving medication. The study investigator will finally record the provider-administered dose of pain medication from the patient's chart.
The management and prediction of pain is one of the most crucial jobs for anesthetists. It has been shown that a patient's ability to remain calm during stressful situations is related to their post-surgical pain scores. The MetroDoloris Analgesia Nociception Index (ANI) monitor is a heart-rate monitor that provides us with a number which reflects a patient's state of relaxation (or parasympathetic tone). For this reason, the investigators are testing whether ANI can be used as a metric for perioperative anxiety, and a predictive tool for pain after c-sections.