Mastocytosis is an orphan disease related to the accumulation and / or the proliferation of abnormal mast cells in different tissues.~In adults, a classic distinction is made between isolated cutaneous forms (10 to 15%) and systemic forms (85 to 90%).~The treatment of systemic mastocytosis has two main axes:~Control of mast cell activation symptoms and~The control of proliferation (accumulation) of mast cells.~There is no standard treatment and no treatment has a marketing authorization for the treatment of monoclonal indolent mastocytosis.
The treatment of systemic mastocytosis has two main axes:~Control of mast cell activation symptoms and~The control of proliferation (accumulation) of mast cells.~There is no standard treatment and no treatment has a marketing authorization for the treatment of monoclonal indolent mastocytosis.