Run-in phase: All eligible patients will enter run-in phase for 2 weeks. In this phase, all oral therapy that patients received before enrolment into the study will be discontinued.~Masking: Opened label~Allocation: Block of four randomization into 2 treatment arms: intravenous iron and oral iron~Safety criteria: Study participants who meet the following criteria will be discontinued from the study. All patients data will be analyzed according to intention-to-treat principles.~Hemoglobin levels < 6.0 g/dl~Packed red cells transfusion is required~Serum ferritin >1,000 md/dl
This study is aim to compare the efficacy of intravenous versus oral iron therapy regarding the hemoglobin levels, iron status and erythropoietin dosage in maintenance hemodialysis patients