During this study patients will receive treatment of omeprazole at the dose depending on group enrollment~Group A will receive omeprazole 80 mg, twice a day for 14 days unless unacceptable toxicity~Group B, will receive omeprazole 20 mg, once a day for 14 days~Patients will receive treatment for 2~3 weeks during the study, and 2 months of follow up.~Total accrual is anticipated to take 2 years.
The purpose of this study is to test the safety of high dose omeprazole and see what effects that it has on patients with exocrine pancreatic cancer.