The primary purpose of this research is to determine if GLA supplementation reduces weight regain over 24 months in Virta Health patients.~The secondary purpose is to determine the effect of GLA supplementation on diabetes-related outcomes.
Weight regain following weight loss is common. In rodent models of obesity and pilot studies in humans, increasing membrane arachidonic acid content improves fuel partitioning and prevents weight regain. This study aims to understand the effect of gamma-linolenic acid (GLA) supplementation on weight loss maintenance in Virta Health patients.