Research Objectives:~To establish a standardized multi-center, prospective DILI cohort nationwide and obtain long-term prognostic data.~To establish and verify prognostic model(s) of DILI in China.~To explore novel serum biomarkers for the prognosis of DILI.
A prospective, multi-center, non-interventional cohort study is going to conduct to explore the clinical characteristics, culprit drug(s) or herb(s), outcomes and risk factors of Drug-induced liver injury (DILI) in China and screen novel serum markers.~A prognostic model incorporating with the novel serum marker(s) for DILI would be established and validated to imporve the prognosis of patients in China .