Setting and location :~Out-patients clinic of Endodontic Department, Faculty of Dentistry, Ain Shams University~Patient allocation:~Using computer generated randomization (www.randome.org), the participants will allocated randomly into three groups .~The sequentially numbers that will be generated, will be placed in opaque envelope until the intervention and each participant will be asked to select an envelope that determine which group of intervention he will be assigned.~Patient Classification:~Patients will be randomly divided into three groups according to material used in pulpotomy Group (1) Biodentine (n=20) Group (2) theracal PT (n=20) Group (3) Neoputty (n=20)~Procedural steps:~Pain scale chart will be given to each patient to rate his /her pain level before endodontic treatment as preoperative reading on a visual analogue scale (VAS)~Tooth will be anaesthetized using Local anesthesia containing Articaine with epinephrine 1:100,000.~Rubber dam isolation of tooth~Tooth surface disinfection using guaze soaked in 5.25% sodium hypochlorite~Access cavity will be performed using a carbide steel round bur and tapered diamond stone until complete deroofing.~Using a sterile excavator, the coronal pulp tissue will be excavated14~Cotton pellets soaked in 2.5 % sodium hypochlorite will be used to achieve hemostasis for 2-3 minutes~Once hemostasis will be achieved one of the three materials will be placed according to the manufacturer's instructions~Final restoration will be placed~Methods of evaluation~Post operative pain~Pulpotomy success rate
The aim of this randomized controlled trial is to assess the post-operative pain as primary outcome and the success rate as secondary outcome after pulpotomy using different calcium silicate based materials in mature permanent teeth diagnosed with irreversible pulpitis.