Observational multicenter retrospective study from january 2011 to january 2021.~No supplementary visit, directly related to the research, will be necessary. This study does not change the usual management of the patient.~Patients will be included after their usual medical check-up.
Fetal colic hyper-echogenicity is a presenting symptoms for cystinuria lysinuria.~A few cases of fetuses with dibasic protein intolerance (more complex prognosis) presented with colic hyper-echogenicity antenatal.~The aim of this retrospective study is to assess the outcome of fetuses with colic hyperechogenicity in order to increase prenatal counseling