This clinical trial examines the effectiveness of a treatment comparing it to another known treatment.~The U.S. Food and Drug Administration (FDA) has approved the navigation bronchoscopy as a treatment option for this disease.~The U.S. Food and Drug Administration (FDA) has approved the Cone-Beam CT scan as a treatment option for this disease.~This research study involves a screening period, a procedure and follow up visits.~The names of the study interventions involved in this study are:~Computed tomography (CBCT)-guided navigation bronchoscopy (CBCT-guided NB)~Navigation bronchoscopy alone~Participants will receive the study procedure and will be followed for up to 6 months.~It is expected that about 136 people will take part in this research study.
The purpose of this study is to determine if the cone beam computed tomography (CBCT)-guided navigation bronchoscopy is better in diagnosing lung nodules compared to navigation bronchoscopy alone.