A Phase 1, First in Human Study of Adenovirally Transduced Autologous Macrophages Engineered to Contain an Anti-HER2 Chimeric Antigen Receptor in Subjects with HER2 Overexpressing Solid Tumors~Main Study - Group 1 and Group 2 all HER2 overexpressing solid tumors~Intraperitoneal Substudy - HER2 overexpressing peritoneal disease~89[Zr] radiolabeled CT-0508 Substudy - All HER2 overexpressing solid tumors (Univ of Penn, Abramson Cancer Center only)~CT-0508 Combination with Pembrolizumab Substudy - All HER2 overexpressing solid tumors
Phase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.