Patients will be followed up annually, according to standard of care.~All diagnostic and therapeutic intervention will be performed according to standard of care, at discretion of the treating physician. In particular, during the study no extra Peripheral blood or Bone Marrow sampling will be performed, in addition to routine sampling for morphology and karyotype surveillance.~Molecular analysis by Next Generation Sequencing (NGS) will also be collected if the centre is doing this on a routine basis.~No Investigational Medicinal Product (IMP) or Non-Investigational Medicinal Product (NIMP) will be given to the patients.
After exiting the RACE trial (NCT02099747) patients will be invited to participate in this long term follow-up study