PRIMARY OBJECTIVE:~I. To determine the prevalence of genetic mutations in cancer patients from various ethnic populations seeking care at Mayo Clinic Arizona and Mayo Clinic Florida cancer clinics.~SECONDARY OBJECTIVES:~I. Perform a chart review to assess the impact of genetic testing as part of standard of oncology care:~Ia. Determine prevalence of pathogenic germline mutation detected by multi-gene panel testing.~Ib. Determine differences in germline mutation detection in these patients as compared to traditional guideline (National Comprehensive Cancer Network [NCCN]) based approach for genetic evaluation.~OUTLINE:~Patients undergo collection of blood or saliva sample for genetic testing.
This clinical trial examines the integration of cancer genetic testing in various ethnic populations. Studying individuals and families at risk of cancer may help identify cancer genes and other persons at risk. The information from this study may provide an opportunity for cancer risk stratification and individualized screening in these ethnic populations.