This study will be a prospective, randomized study of patients who are undergoing one or more of the following procedures at ASLMC:~Large-Bore Procedures >13 F~WATCHMAN® device placement~Atrial fibrillation/flutter/SVT ablation using cryoballoon or laser balloon~Leadless pacemaker~Pulmonary embolism thrombectomy (Inari FlowTriever system)~MitraClip transcatheter mitral valve repair~RANDOMIZATION:~Patients will be randomized into one of two venous closure groups after a clean stick has been achieved with no complications:~Large-bore (14F-25F) venous access group (1:1)~Perclose ProGlide SMC~Figure 8 suture
Primary objective: To compare the safety and efficacy of closure strategies post venous access procedures.~Hypothesis: We anticipate that the use of a venous closure device will decrease the time to hemostasis (TTH), time to ambulation (TTA) and time to discharge (TTD) compared to conventional methods of closure following venous access procedure.