For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with .~The aim of this study is to investigate the feasibility of neostigmine just after tracheal intubation on the IONM in thyroid surgery.~This study will be performed as a randomized controlled trial with two groups (N group: neostigmine group and NS group: normal saline group).~For the N group, neostigmine (0.03 mcg / kg) and glycopyrrolate with a 5:1 ratio will be administered just after tracheal intubation.~For the NS group, normal saline with a same volume of the N group will be administered just after tracheal intubation.~For all patients of two groups, investigators evaluate the quality of signal of IONM during the surgery.
For successful intraoperative neuromonitoring (IONM), adequate reversal of neuromuscular blocking agent is a prerequisite in thyroid surgery with .~The aim of this study is to investigate the feasibility of neostigmine just after tracheal intubation on the IONM in thyroid surgery.