The ESASO morphologic classification of diabetic macular edema defines four stages of progression of the disease: early, advanced, chronic and atrophic maculopathy.~This grading is generated by the analysis of seven biomarkers that fully describe the level of retinal damage. Aim of this classification is to be a valid method for a comprehensive description of DME in scientific studies or clinical practice.~Given the recent publication of ESASO Classification, there aren't observations on the real relevance of grading DME on therapeutic outcome.~This retrospective study wants to give a preliminary answer to this important issue.~As a corollary outcome, this study will also evaluate the concordance of grading among participants.
Retrospective multi-center observational study on functional and morphological outcome of initial therapy for DME according to ESASO Morphologic Classification.