Aim of the Work~Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester.~Hypothesis:~Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester.~Research question:~Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester?~Primary outcome:~Complete abortion (complete expulsion of products of conception with no need for curettage) within one week from the first dose of misoprostol.~Secondary outcome:~• Curettage (surgical evacuation of the products of conception)~Incomplete abortion (retained products of conception).~Considerable bleeding that necessitates immediate evacuation.
Aim of study Compare the success rate of misoprostol with versus without letrozole as a pretreatment for medical termination of pregnancy during the first trimester.~Hypothesis:~Letrozole value as a pre-treatment medication for misoprostol in induction of abortion during the first trimester.~Research question:~Will letrozole- misoprostol protocol give better results than misoprostol- alone protocol in induction of abortion during the first trimester?