this study is conducted to investigate the clinical efficacy and safety of cryolipolysis on fat removal of thigh through cryolipolysis.~Healthy premenopausal volunteered women had been conducted to assess their anthropometrical, social, and cardio-metabolic, and femoral fat amount by computer tomography, and adverse events at initial, 4 week, 12 week visit.
There was no difference in efficacy in removal of local fat on thigh by cryolipolysis through Zeltiq machine.~Cryolipolysis was found to be safe for 12 week clinical trial.