All patients who meet the inclusion criteria and giving written informed consent will be randomized.~Every patient will be treated with a single injection of Filtered Autologous Adipose Tissue in one knee and single injection of Placebo in the other, based on the randomization.~After the treatment patients will be followed up to 24 months.
The purpose of the study is to assess the radiological and clinical outcomes comparing two different treatments (Filtered Autologous Adipose Tissue versus Placebo) in patients affecting bilateral knee osteoarthritis.~After be randomized, every patient will be treated in both legs, one leg with Adipose Tissue and the other one with Placebo.