Through recruitment of a racially, geographically, and socioeconomically diverse sample of patients, we will achieve the following aims:~Evaluate factors associated with access to genetic risk assessment, counseling, and testing services~Conduct a randomized controlled trial to assess the effectiveness of interventions on improving guideline-adherent CRM and FC of genetic test results~Create and pilot an adaptive intervention to tailor resources to promote CRM and FC~Document and compare multiple implementation outcomes across the different interventions to maximize their effectiveness and improve reach to underserved populations
The IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of genetic test results. These interventions will be delivered to individuals with a documented pathogenic/likely pathogenic (P/LP) variant or variant of uncertain significance (VUS) in an inherited cancer gene.