Aims and Hypothesis to be tested:~The investigators hypothesized that the derived organoid should have a similar morphological and genetic mutation signatures to the patient primary tissue.~Study period: 1 year for patient recruitment and organoid generation from patient tumor~Study population: 30~Study samples:~Patient's meningioma tumor sample are collected from patients with surgical needs. Sample collected are used for organoid culture. Morphological and genetic characteristics will be compared between the patient tumor sample and the corresponding derived organoids~Primary outcome measures:~Whole exome sequencing data of patient tumor tissue and patients-derived organoids
In this study, meningioma organoids will be established from patients' tissues and the characterization of the organoid will be performed.