Objectives:~To establish the maximum tolerated dose of ketamine in combination with gabapentin up to a maximum planned dose of 40 mg three times a day.~To evaluate feasibility and tolerability~Exploratory:~- To assess pain, symptom burden, functionality, and quality of life
This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.