A total of 116 patients selected for laparoscopic colorectal surgery from March 2021 to June 2022 were randomly divided into four groups (n=29) : For normal weight patients, the medication group was given according to the lean body mass (NL group), the medication group was given according to the actual weight of normal weight patients (NR group), the medication group was given according to the lean body mass of obese weight patients (OL group), and the medication group was given according to the actual weight of obese weight patients (OR group). All the four groups maintained intraoperative deep neuromuscular blockade(PTC≤2). The dosage of cisatracurium, time to effect, time to recovery from four clusters of stimuli, recovery index, extubation time, and time to stay in PCAU(postanesthesia care unit) were recorded.
To observe the pharmacodynamics of intravenous injection of cisatracurium to maintain deep neuromuscular blockade in obese patients with lean body mass in laparoscopic colorectal surgery