Perioperative anaemia is one of the most common comorbidities in patients undergoing surgery, with a prevalence of up to 30% in patients undergoing cardiac surgery. Perioperative anaemia can lead to ischaemia and hypoxia in vital organs, increased postoperative complications and even increased mortality; in addition to an increased rate of allogeneic blood product transfusions and significantly longer ICU and hospital stays. Correcting perioperative anaemia and reducing complications are of great importance to improve the immediate and long-term prognosis of patients undergoing major cardiac surgery.
This study was designed to investigate the effect of iron sucrose combined with rHuEPO and ascorbic acid on perioperative allogeneic red blood cell transfusion in patients undergoing elective major cardiac surgery by evaluating outcome indicators such as perioperative allogeneic red blood cell transfusion rates and changes in perioperative haemoglobin levels.