Progesterone plays a key role in embryo implantation and maintenance of pregnancy.~In the context of Assisted Reproduction (ART), support for the luteal phase is often necessary and readily provided by the administration of progesterone, mainly vaginal in Europe.~Optimal absorption is essential because low progesterone levels are associated with the chances of lowered pregnancies.~However, it has been shown that vaginal absorption can be reduced following unprotected sex.~Would the use of a condom prevent this alteration of vaginal absorption?
The objective of this project is to compare the vaginal absorption of progesterone administered in the vaginal ovum by measuring progesteroneemia in 3 situations (or sexual event): abstinence, sex protected by condoms and unprotected sex.