In this trial, subjects who fulfil all inclusion and exclusion criteria are enrolled.~Eligible subjects will be randomised in a 2:1 ratio to MC2-25 cream or MC2-25 vehicle, respectively.~The subjects will apply the assigned investigational medicinal product (IMP) twice daily for 12 weeks.
The purpose of this study is to access the efficacy and safety of MC2-25 cream and MC2-25 vehicle for treatment of chronic kidney disease associated pruritus (CKD)-aP).