Description of Study Procedures and In-Office Visit:~Enrollment/Screening:~At the Enrollment/ Screening Visit, the exams will be conducted in the following order:~Patient will be informed concerning the study and sign the Informed Consent Form (ICF) prior to conduct of any study procedures.~The following data will be collected for each study subject:~Subject's DOB~Gender~Number and type of injections and last injection date~The following data will be collected for the study eye:~Qualifying diagnosis for the study eye from the subject's medical record~From the subject's medical record, the presence of other ophthalmic conditions including but not limited to:~i. Cataract ii. Glaucoma iii. Dry Eye iv. Other macula findings, e.g., epi retinal membrane, macular hole, vitreo-macular traction (VMT)~Refraction correction~Snellen BCVA on both eyes on the day of the visit.~Selecting the study eye:~Both eyes of the subject will be scanned, non-dilated, with a Zeiss Cirrus OCT device to get an acceptable single volume scan per eye. Scanning pattern to be used: Macular cube, 6X6mm, 128 B-scans per volume scan~The PI/CoPI will read the Zeiss Cirrus OCT scans of both eyes and will grade each eye for the presence/absence of SRF and/or IRF in the retina~The eye with SRF and/or IRF will be set as the study eye. In case both eyes were graded as fluid-present, the study eye will be set randomly~The Zeiss Cirrus OCT scan of the study eye will be part of the study analysis~NOTE: Any planned treatment for NV-AMD should be administered after completion of all study-related scans~OCT Scans:~The study eye of the subject will be scanned once, non-dilated, with a Zeiss Cirrus OCT device to get an acceptable single volume scan of the study eye in each repetition.~Scanning pattern to be used: Macular cube, 6X6mm, 128 B-scans per volume scan~Following the Zeiss Cirrus OCT scans, the subject will be placed in a room with the Notal OCT V3.0 device which has been set up by a technician.~Notal OCT V3.0 scans~The technician will register the subject using the touchscreen of the Notal OCT V3.0 device and the assigned Subject ID.~On the first Notal OCT V3.0 device the subject will perform a self-tutorial.~The technician will set the first Notal OCT V3.0 for self-scan of the study eye. The subject will perform the tutorial on the eye with better vision, based on the subject's subjective decision, even if that eye is not the study eye. Then, the subject will perform on the first device- a calibration, and 5 volume scans.~The technician will set the second device for self-scans of the study eye. The subject will perform calibration and 5 volume scans.~The subject will be able to rest 1-2 minutes between self-scans~Collect AEs, if applicable.~Exit the subjects from the study.
The study will enroll up to 30 AMD patients diagnosed with NV-AMD in at least one eye at the time of enrollment. At the Study Visit, fluid must be present in at least one eye of the subjects. If only one eye qualifies for enrollment, that will be assigned as the study eye. If both eyes are eligible, the study eye will be assigned according to a randomization schedule. Only one eye of each subject will be enrolled in the study. All subjects will be enrolled at 1 site in the United States. Subjects must meet all inclusion and no exclusion criteria.