study enrolling 30 patients of localized psoriasis. 15 patients received intralesional methotrexate :~Taking aseptic condition ,One psoriatic plaque will treated with Intralesional injection of methotrexate (25mg /ml) at dosage of 0.1 ml /cm2.~Another plaque will treated with intralesional ingection of distilled water as controlled plaque.~patient will receive oral folic acid 5mg tablet every day except the day of injection.~Other 15 patients received intralesional trimethinolone acetonide:~Taking aseptic condition , One plaque will treated with Intralesional injection of trimethinolone acetonide (10mg/ml) at dosage of 0.1 ml/ cm2 .~another plaque will treated with Intralesional injection of distilled water as controed plaque.~Patients will take 6 sessions every 2 weeks for 3 months and will followed up at 2 month and 3 months after treatment .
The aim of the present study is to evaluate the efficacy of intralesional injection of methotrexate in comparison with Intralesional Injection of Triamcinolone Acetonid in localized psoriasis (body surface area < 10%) .