This was a single center, Phase 1, open-label SAD and MAD study designed to assess safety, tolerability and PK of orally administered THR-1442 tablets in Chinese healthy adults.~Subjects were enrolled to receive 20mg THR-1442 tablet in Single dose group (20mg*1 day) and multiple dose group(20mg*7days).~Blood samples for THR-1442 plasma concentrations were collected 0h till to 48hours.
The purpose of this study was to investigate Safety, tolerability and pharmacokinetics in Chinese healthy subjects.