The study has three main objects:~to evaluate the optimal time of blood sampling (gestational week 7-8 or 11-14)~to evaluate whole genome amplification prior to genetic analysis og isolated fetal cells (only relevant for monogenic disorders)~evaluating specificity and sensitivity compared to chorionic villus sampling
The study aims to evaluate cell-based non-invasive prenatal testing (cbNIPT) as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for hereditary disorders.