The study is prospective, comparative, open label. Participants are Vietnamese children. Prescribing drops : 1 drops/eye/night/ 12 months Wash-out: 12 months The atropine drops in this study are commercially available.
The goal of this clinical trial is to compare the efficacy of 2 low-dose atropine drops (0,01%; 0,05%) in Vietnamese children. The main questions it aims to answer are:~How is the difference in efficacy among 3 groups: atropine 0,01% vs 0,05% vs spectacles?~How is the difference in side effects among 3 groups: atropine 0,01% vs 0,05% vs spectacles?~How is the difference in rebound phenomena between 2 atropine groups?