Non-pharmacological, non-interventional, prospective, monocentric study involving the use of biological materials.~There will be two cohorts:~COVID + cohort: 50 patients with positive nasopharyngeal swab and / or BAL.~Control Cohort: 20 patients with non-SARS-CoV-2 related pneumonia.~The study involves analyzing biological samples collected for normal clinical practice.~In particular:~blood samples will be used for PROS and Sflt1 assay, haematological, biochemical and coagulation tests.~Samples deriving from nasopharyngeal swab or from Broncho-Alveolar Lavage (BAL) liquid will be used for Real time PCR analysis to evaluate the viral load of SARS CoV-2.
The aim of this study is to compare plasma S Protein levels to SARS-CoV-2 viral load in COVID positive patients.