Hirschsprung disease (HD) is a distinctive congenital disease with the absence of ganglion cells in the distal intestine leads to distal bowel obstruction and defecation disorders. HD is a rare disease, with a reported incidence of 1:5,000, requiring proper surgical treatment for the maintenance of normal or near-normal bowel movement.To date, there is insufficient evidence to recommend a preferred or superior method for the surgical repair, and a transanal endorectal pull-through or laparoscopic-assisted transanal endorectal pull-through was the most common procedure for correction of HD,which may have faster recovery and less rate of complication compared to other surgical approaches.The outcomes of HD has been widely evaluated in the past decades,and bowel dysfunction,consist of soling, incontinence and constipation, had been proven as the most common complication,which may be a ongoing issue and lead to social problems,which should not be ignored. A lot of studies has been designed to explore the trend toward to normal bowel habits from preschool and early childhood age to adolescence or adult,however,no identified improvement of bowel habits was completely confirmed.In contrast,there were many reports proved that poor bowel function in preschool and early childhood may lead to social problems and depression in adolescence or adult.The reasons of poor dysfunction of HD in preschool and early childhood were complicated and undefined,including length of aganglionic segement,anastomotic leakage or redo-PT,unsuitable timing of surgery,etc.Thus,the present study was designed to seek the risk factors for bowel dysfunction of HD,which is meaningful to maintain or improve the bowel function in preschool and early childhood.
Bowel dysfunction has been proven as the most common complication after pull-through(PT) of Hirschsprung disease(HD) at preschool and early childhood age,which may persist to adulthood and lead to social problems.The reason of bowel dysfunction is complicated and the risk factors were not defined.The present study was designed to seek the risk factors for bowel dysfunction of HD at preschool and early childhood age.