For each patient the following will be done :~History taking including ( age, sex, disease duration, family history, history of drug intake, smoking and history of any associated disease ).~All patients will give a written, informed consent for induction.~Basic photographs will be taken to assess site, size (by cm), number, Extent of the patch using D5300 camera with lens (18-55).~Patients will be subjected to 3 session of trichloroacetic acid (TCA) 35% one month apart.~serial photographs and dermoscopic examination every month will be done and patient will be score.~Efficacy will be assessed using prognostic scoring system for density, pigmentation, and texture of growing hair.~histopathological examination will be done before the first session and one month after third session.
Abstract: Alopecia areata is believed to be an autoimmune disease resulting from a breach in the immune privilege of the hair follicles causing non scarring hair loss.~Methods: our study included 40 patients from may 2019 to july 2022 diagnosed clinically, dermatoscopically and pathologically as alopecia areata Data were enrolled from department of dermatology and venereology, Al-Hussein hospital.