A total of 40 subjects will be divided into two parts for manual scoring, which includes not only the accuracy of the discrimination to FYTF-919 or placebo independently, which is the primary outcome in this study, but also the physical (color, odor, taste) consistency of the two drugs. Another important outcome from manual scoring is the accuracy of the discrimination between FYTF-919 and placebo determined by random self-cross-control. Intelligent sensory technology scoring is also used to compare differences in smell and taste. That is, the electronic nose technology and the electronic tongue technology were used to compare the consistency of odor related parameters and taste related parameters of the two drugs, and the similarity was compared.
TCM is an essential context of the ICH management in Chinese culture. Given the potential benefits of Chinese herbal medicine FYTF-919 in reducing haematoma and bleeding after acute ICH from fundamental research and small clinical studies, more reliable evidence is required to guide ICH treatment using TCM. This study is based on manual scoring and intelligent sensory technology scoring methods, which are used to compare physical consistency between preparation of FYTF-919 and its placebo, simultaneously the two drugs are evaluated in a blinded way. Therefore, the efficacy of placebo preparation of FYTF-919 and feasibility of its application in randomized, double-blind, placebo-controlled clinical trials will be obtained.