Synthesis and evaluation of a novel series of phosphodiesterase IV inhibitors. A potential treatment for asthma.
Beasley SC, Cooper N, Gowers L, Gregory JP, Haughan AF, Hellewell PG, Macari D, Miotla J, Montana JG, Morgan T, Naylor R, Runcie KA, Tuladhar B, Warneck JB.
The synthesis and pharmacological profile of a novel series of potent and selective phosphodiesterase type IV (PDE IV) inhibitors is described.