Synthesis and screening of (E)-1-(β-D-galactopyranosyl)-4-(aryl)but-3-ene-2-one against Mycobacterium tuberculosis.
Mugunthan G, Ramakrishna K, Sriram D, Yogeeswari P, Ravindranathan Kartha KP.
A series of galactose-derived aryl enones were synthesised and screened against Mycobacterium tuberculosis H(37)Rv. Preliminary results were promising with MIC values in the range 1.56-12.5 μg/mL.