Efficacy of benzoxazinorifamycins in a mouse model of Chlamydia pneumoniae lung infection.
Campbell LA, Kuo CC, Suchland RJ, Rothstein DM.
The efficacy of rifalazil and other benzoxazinorifamycins was tested in a mouse model of lung infection against Chlamydia pneumoniae. Rifalazil and six related new chemical entities all showed efficacy after one dose per day for 3 days at either 3 or 1 mg/kg of body weight.