Data for DCP probe BAY-678
SGC Frankfurt
SGC Frankfurt donated chemical probe project: BAY-678 was donated by Bayer. Website: https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/BAY-678. Control: BAY-677. References: 1. von Nussbaum, Franz, Volkhart M J Li, Swen Allerheiligen, Sonja Anlauf, Lars Bärfacker, Martin Bechem, Martina Delbeck, Mary F Fitzgerald, Michael Gerisch, Heike Gielen-Haertwig, Helmut Haning, Dagmar Karthaus, Dieter Lang, Klemens Lustig, Daniel Meibom, Joachim Mittendorf, Ulrich Rosentreter, Martina Schäfer, Stefan Schäfer, Jens Schamberger, Leila A Telan, and Adrian Tersteegen. 2015. ‘Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases’. ChemMedChem 10(7):1163–73. PMID: 26083237 (Compound 20).