title: Analysis of 3d image data as 2d
body: <p>I have a tif image of size around ~10 Gb. I need to perform object classification or pixel classification in this image. The dimension of image data has zyx form. My voxel size in x=0.6, y=0.6 and z=1.2. Z is the depth of the object. My RAM can not take whole image. </p>
  
  <p>If I do classification of pixels in each Z plane separately and then merge to get the final shape and volume of object. </p>
  
  <p><strong>Would I loose any information and my final shape or volume of object will be wrong?</strong>   </p>