title: Application '/LM/W3SVC/1/ROOT/' with physical root '' failed to load clr and managed application
body: <p>My Web API runs OK most of the time in IIS v.10 on Windows Server 2016. However, an error occurs from time to time and I can't figure out the error source or cause. The corresponding Windows Logs/Application error log record is as follows</p>
  
  <pre><code>    Application '/LM/W3SVC/1/ROOT/MyWebAPI' with physical root '....\MyWebAPI\' failed to load clr and managed application. 
  Managed server didn't initialize after 120000 ms.
     Process Id: 4840. 
     File Version: 12.2.19169.6. Description: IIS ASP.NET Core Module V2 Request Handler. Commit: e7f262e33108e92fc8805b925cc04b07d254118b 
  </code></pre>
  
  <p>The error results in <em>HTTP Error 500.30 - ANCM In-Process Start Failure</em> on the client side. After that, MyWebAPI stops working and I have to recycle MyWebAPI application pool manually. 
  Can anybody help, please? </p>