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Prion Biology (Perspectives CSHL) (Editor: Stanley… - 9781621820932 - koop boek
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9781621820932 (?) of 1621820939
, in Engels, Cold Spring Harbor Laboratory Press, hardeband, Nuwe
Prion-Biology~~Stanley-B-Prusiner, Prion Biology, Hardcover
Data uit 2017-05-11 07:55h
ISBN (alternatiewe skryfwyses): 1-62182-093-9, 978-1-62182-093-2
Editor: Stanley B. Prusiner (?):
Prion Biology (Perspectives CSHL) (2017) (?)
9781621820932 (?) of 1621820939
, in Engels, 352 bladsye, Cold Spring Harbor Laboratory Press, hardeband, Nuwe, eerste uitgawe
Prions are best known as the agents of mad cow and related diseases, and a growing number of proteins with prion-like properties have been implicated in diseases such as Parkinson's. But some recently discovered prion-like proteins do not appear to induce pathological changes and, in fact, may be key players in basic biological processes such as transcription, immune regulation, and memory formation.Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology examines the expanding roles of prions and prion-like proteins in health and disease. The contributors review the structures of prions and prion-like proteins, how they aggregate into amyloid fibrils and other insoluble complexes, and the unique biological properties of the aggregated forms (E.g., infectivity, gain/loss of function, and self-templating). The normal physiological roles of prion-like proteins (E.g., CPEB in the brain and MAVS in the immune response) are discussed, as is the formation of abnormal protein aggregates via prion-like mechanisms in various human diseases.The authors also discuss prions in yeast and other fungi, which are convenient models for studying mechanisms of amyloid formation and propagation. This volume is therefore an essential reference for biochemists, cell and molecular biologists, and all who wish to understand how these alternatively folded, self-propagating proteins function., Hardcover, Edition: 1, Label: Cold Spring Harbor Laboratory Press, Cold Spring Harbor Laboratory Press, Product group: Book, Published: 2017-07-31, Studio: Cold Spring Harbor Laboratory Press, Sales rank: 4887634
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Data uit 2017-05-11 07:55h
ISBN (alternatiewe skryfwyses): 1-62182-093-9, 978-1-62182-093-2
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