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Now showing items 1-20 of 44
Effect of ghrelin on glucose-insulin homeostasis: therapeutic implications
Sangiao-Alvarellos, Susana; Cordido, Fernando (Hindawi, 2010)
[Abstract] Ghrelin is a 28-amino-acid peptide that displays a strong growth hormone- (GH-) releasing activity through the activation of the growth hormone secretagogue receptor (GHSR). The first studies about role of ghrelin ...
Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients
Pérez-Fontán, Miguel; Rodríguez Carmona, Ana; Barreda, D.; López-Muñiz, Andrés; Blanco-Castro, N.; García Falcón, María Teresa (Karger, 2010)
[Abstract] Background: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Method: Observational study of a cohort of 269 patients starting PD in a single unit. ...
Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism
Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)
[Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...
Changes in hypothalamic expression of the Lin28/let-7 system and related MicroRNAs during postnatal maturation and after experimental manipulations of puberty
Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Ruiz-Pino, Francisco; Navarro, V.M.; Sánchez-Garrido, M.A.; León, Silvia; Diéguez, Carlos; Cordido, Fernando; Matagne, V.; Dissen, G.A.; Ojeda, S.R.; Pinilla, Leonor; Tena-Sempere, Manuel (Endocrine Society, 2013)
[Abstract] Lin28 and Lin28b are related RNA-binding proteins that inhibit the maturation of miRNAs of the let-7 family and participate in the control of cellular stemness and early embryonic development. Considerable ...
Resultados del trabajo cooperativo de los registros españoles de diálisis peritoneal: análisis de 12 años de seguimiento
Remón Rodríguez, César; Quirós Ganga, Pedro; Portolés-Pérez, José; Gómez-Roldán, Carmina; Miguel-Carrasco, Alfonso; Borrás Sans, Mercé; Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sánchez-Álvarez, Emilio; Rodríguez Suárez, Carmen (Sociedad Española de Nefrología, 2014)
[Resumen] Introducción y objetivos: Actualmente no existe un registro que muestre en su conjunto y globalidad la realidad de la diálisis peritoneal (DP) en España. Sin embargo, para distintos congresos y reuniones se ha ...
Importance of exercise in the control of metabolic and inflammatory parameters at the moment of onset in type 1 diabetic subjects
Martínez-Ramonde, T.; Alonso, N.; Cordido, Fernando; Cervelló, E.; Cañizares, Angelina; Martínez-Peinado, P.; Sempere, J.M.; Roche, E. (Thieme, 2014-05-05)
[Abstract] The onset of type 1 diabetes coincides with the final phase of B-cell destruction. In some cases, this period is characterized by the presence of a functional reserve of B-cells, favouring an adequate metabolic ...
Compared decline of residual kidney function in patients treated with automated peritoneal dialysis and continuous ambulatory peritoneal dialysis: a multicenter study
Pérez-Fontán, Miguel; Remón Rodríguez, César; Borrás Sans, Mercé; Sánchez Álvarez, Emilio; da Cunha Naveira, Marta; Quirós Ganga, Pedro; López-Calviño, Beatriz; Rodríguez Suárez, Carmen; Rodríguez-Carmona, Ana (Karger, 2015-01-08)
[Abstract] BACKGROUND: There is controversy concerning the compared rates of decline of residual kidney function (RKF) in patients treated with continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal ...
Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome
Margusino-Framiñán, Luis; Pértega-Díaz, Sonia; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Pita-Gutiérrez, Francisco; Pita-Fernández, Salvador; Cordido, Fernando (Elsevier, 2015-08-20)
[Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment.  Objective. Taking the results of an earlier ...
Influence of Age on Rat Bone-Marrow Mesenchymal Stem Cells Potential
Fafián Labora, Juan Antonio; Fernández-Pernas, Pablo; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Oreiro, Natividad; Sangiao-Alvarellos, Susana; Mateos, Jesús; Arufe, M.C. (Nature, 2015-11-19)
[Abstract] Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone ...
Adenomas hipofisarios no funcionantes: valoración de la invasión, persistencia, recurrencia y del índice de proliferación celular Ki-67
García Sancho de la Jordana, P.; Pia Marengo, A.; San Martín Tresols, L.; Simó Servat, A.; Arcano, Karina; Vidal, N.; Triviño, Vanessa; Iglesias, P.; Cordido, Fernando; Villabona, Carles (Elsevier, 2016)
Adenoma hipofisiario no funcionante: estudio clínico y patológico
Triviño, Vanessa; García, P.; Díez, J.J.; Cordido, Fernando; Villabona, Carles; Iglesias, P.; Arcano, Karina (Elsevier, 2016)
La expresión génica de FNDC5 en distintos tejidos, y los niveles circulantes de irisina, están modificados por la dieta y las condiciones hormonales
Cordido, Fernando; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Pena-Bello, Lara; Sangiao-Alvarellos, Susana (Elsevier, 2016)
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
Varela-Rodríguez, Bárbara María; Pena-Bello, Lara; Juiz-Valiña, Paula; Vidal Bretal, Beatriz; Cordido, Fernando; Sangiao-Alvarellos, Susana (Nature, 2016-07-19)
[Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ...
Circulating levels of irisin in hypopituitary and normal subjects
Pena-Bello, Lara; Pértega-Díaz, Sonia; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Eiras-Leal, Raquel; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Pérez-Fontán, Miguel; Cordido, María; Cordido, Fernando (PLoS ONE, 2016-07-29)
[Abstract] Context. The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP) is a situation characterized by decreased GH secretion and an ...
Serum levels of the adipomyokine irisin in patients with chronic kidney disease
Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel; Sangiao-Alvarellos, Susana; García Falcón, María Teresa; Pena-Bello, Lara; López-Muñiz, Andrés; Cordido, Fernando (Elsevier, 2016-12-14)
[Abstract] Background. Irisin is an adipomyokine with claimed anti-obesity and anti-diabetic effects. This hormone has been insufficiently studied in patients with advanced chronic kidney disease (CKD).  Objective. To ...
Treatment adherence to pegvisomant (somavert®) in Spain: PEGASO study
Cámara, Rosa; Venegas, Eva; García-Arnés, Juan Antonio; Cordido, Fernando; Aller, J.; Martín, Víctor; Sánchez-Cenizo, Laura; Mir, Nuria (Oxford, 2017)
¿Existe relacion entre los parametros de composicion corporal y el riesgo de infección peritoneal (IP) en dialisis peritoneal (DP)?: estudio longitudinal
Fiel, D. Carvalho; López-Iglesias, Antía; García-Enríquez, Alba; García Gago, L.; Bravo González-Blas, L.; Otero Alonso, P.; Rodríguez-Carmona, Ana; Pérez-Fontán, Miguel (Sociedad Gallega de Nefrología, 2017)
Low serum levels of vitamin D are associated with progression of subclinical atherosclerotic vascular disease in peritoneal dialysis patients: a prospective, multicenter study
Pérez-Fontán, Miguel; Borrás Sans, Mercé; Bajo Rubio, María Auxiliadora; Rodríguez Carmona, Ana; Betriu, Angels; Valdivielso, José Manuel; Fernández, Elvira (Karger, 2017-02-25)
[Abstract] Background: The prevalence of subclinical atherosclerosis and the main predictors of progression of this condition in patients undergoing peritoneal dialysis (PD) have been insufficiently investigated. Objectives ...
Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test
Pena-Bello, Lara; Seoane-Pillado, Teresa; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Cordido, María; Cordido, Fernando (Elsevier para European Federation of Internal Medicine, 2017-06-09)
[Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...
Peritoneal water transport characteristics of diabetic patients undergoing peritoneal dialysis: a longitudinal study
Fernandes, Ana; Ribera-Sánchez, Roi; Rodríguez Carmona, Ana; López-Iglesias, Antía; Leite-Costa, Natacha; Pérez-Fontán, Miguel (Karger, 2017-06-21)
[Abstract] Background: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal ...
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