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Mathematical analysis of sequenced aptamer pools after the Next Generation Sequencing which allows us to choose leading sequences and to estimate the enrichment of aptamers during selection
Estimation of affinity, specificity and dissociation constant of synthetic aptamers using flow cytometry and laser scanning microscopy
Aptamer DESIGN AND 3D Structure
Definition of the of aptamer tertiary structure in buffer using Small Angle X-ray Scattering with the following molecular design
Target Identification and Verification
Protein target identification using Aptamer-facilitated Biomarker Discovery technique and mass-spectrometry analysis with the following target verification by concurrent antibody replacement and co-staining.
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