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Tamura Lab : Yamagata Univ.
37. Kudo S., Shiino H., Furuta S., Tamura Y.* (2020) Yeast transformation stress, together with loss of Pah1, phosphatidic acid phosphatase, leads to Ty1 retrotransposon insertion into te INO4 gene FASEB J., 34(3) 4749-4763.
33. Sakaue H., Shiota T., Ishizaka N., Kawano S., Tamura Y., Tan KS., Imai K., Motono C., Hirokawa T., Taki K., Miyata N., Kuge O., Lithgow T., and Endo T.* (2019) Porin Associates with Tom22 to Regulate te Mitochondrial Protein Gate Assembly Mol. Cell, 73, 1044–1055
32. Sawasato K., Sato R., Nishikawa H., Iimura N., Kamemoto Y., Fujikawa K., Yamaguchi T., Kuruma Y., Tamura Y., Endo T., Ueda T., Shimamoto K. and Nishiyama K.* (2019) CdsA is involved in biosynthesis of glycolipozyme MPIase essential for membrane protein integration in vivo. Sci. Rep., 9, Article number: 1372
31. Ueda E., Tamura Y., Sakaue H., Kawano S., Kakuta C., Matsumoto S., and Endo T.* (2019) Myristoyl group-aided protein import into te mitochondrial intermembrane space. Sci. Rep., 9, Article number: 1185.
30. Kojima R., Kakimoto Y., Furuta S., Itoh K., Sesaki H., Endo T., and Tamura Y.* (2019) Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport. Cell Rep., 26, 518–528.
29. Tashiro, S. Caaveiro, J. Nakakido, M. Tanabe, A. Nagatoishi, S. Tamura, Y. Matsuda, N. Liu, D. Hoang, Q. and Tsumoto, K.* (2018). Discovery and Optimization of Inhibitors of te Parkinson's Disease Associated Protein DJ-1. ACS. Chem. Biol., 13(9):2783-2793. doi: 10.1021/acschembio.8b00701.
28. Kakimoto, Y. Tashiro, S. Kojima, R. Morozumi, Y. Endo, T. & Tamura, Y.* (2018) Visualizing multiple inter-organelle contact sites using te organelle-targeted split-GFP system. Sci. Rep., 8, Article number: 6175. doi:10.1038/s41598-018-24466-0
27. Kawano, S. Tamura, Y. Kojima, R. Bala, S. Asai,  Michel, EA. Kornmann, B. Riezman, I.Riezman, H. Sakae, Y. Okamoto, Y. and Endo T.* (2018). Structure–function insights into direct lipid transfer between membranes by Mmm1–Mdm12 of ERMES.
J. Cell. Biol. 217, 959–974. DOI: 10.1083/jcb.201704119.
26. Miwa, K., Kojima, R., Obita, T., Ohkuma, Y., Tamura, Y., and Mizuguchi, M.* (2016). Crystal Structure of Human General Transcription Factor TFIIE at Atomic Resolution. J. Mol. Biol. 428, 4258-4266. doi: 10.1016/j.jmb.2016.09.008.
25. Kojima R. Kajiura S. Sesaki H. Endo T. Tamura Y.* (2016) Identification of multi-copy suppressors for endoplasmic reticulum-mitochondria tethering proteins in Saccharomyces cerevisiae. FEBS Lett. 590, 3061-70. DOI: 10.1002/1873-3468.12358
24. Arakawa S. Yunoki K. Izawa T. Tamura Y. Nishikawa S and Endo T.* (2016) Quality control of nonstop membrane proteins at te ER membrane and in te cytosol. Sci. Rep. 6, Article number: 30795; doi: 10.1038/srep30795
23. Kojima. R. Endo T. and Tamura Y.* (2016) A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. Sci. Rep. 6, Article number: 30777 doi:10.1038/srep30777
22. Miyata N. Watanabe Y. Tamura Y. Endo T. and Kuge O.* (2016) Phosphatidylserine transport by Ups2-Mdm35 for phosphatidylethanolamine synthesis in respiration-active mitochondria. J. Cell Biol. 214, 77-88. doi: 10.1083/jcb.201601082
21. Watanabe, Y., Tamura, Y., Kawano, S., and Endo T.* (2015) Structural and mechanistic insights into phospholipid transfer by Ups1–Mdm35 in mitochondria. Nat. Commun. 6, Article number: 7922 doi:10.1038/ncomms8922
20. Koyano F., Okatsu K., Kosako H., Tamura Y., Go E., Kimura M., Kimura Y., Tsuchiya H., Yoshihara H., Hirokawa T., Endo T., Fon EA., Trempe J., Saeki Y., Tanaka K.* and Matsuda N.* (2014) Ubiquitin is phosphorylated by PINK1 to activate Parkin. Nature, 510,162-166
19. Song, J., Tamura Y., Yoshihisa T. and Endo T.* (2014) A novel import route for an N-anchor mitochondrial outer membrane protein aided by te TIM23 complex (2014) EMBO Rep.,15, 670-677.
18. Okamoto, H., Miyagawa, A., Shiota, T., Tamura, Y. and Endo, T.* (2014) Intra-molecular disulfide bond of Tim22 maintains integrity of te TIM22 complex in te mitochondrial inner membrane. J. Biol. Chem., 289, 4827-4838.
17. Tamura, Y., Harada, Y., Nishikawa, S., Yamano, K., Kamiya, M., Shiota, T., Kuroda, T., Kuge, O., Sesaki, H., Imai, K., Tomii, K. and Endo, T.* (2013) Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria. Cell Metab., 17, 709-718.
16. Itoh, K., Tamura, Y., Iijima, M. and Sesaki, H.* (2013) Effects of Fcj1-Mos1 and mitochondrial division on aggregation of mitochondrial DNA nucleoids and organelle morphology. Mol. Biol. Cell, 24, 1842-1851.
15. Tamura Y.*, Onguka O, Itoh K, Endo T, Iijima M, Claypool S.M.*, Sesaki H* (2012) Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P.  J. Biol. Chem., 287, 43961-43971. *Co-corresponding authors.
14. Shiota, T.†, Maruyama, M.†, Miura, M.†, Tamura, Y.†, Yamano, K., Esaki, M. and Endo, T.* (2012) Te Tom40 assembly process probed using te attachment of different intramitochondria sorting signals. Mol. Biol. Cell, 23, 3936-3947. †Equal contribution.
13. Tamura, Y.*, Onguka, O., Aiken Hobbs, A.E., Jensen, R.E., Iijima, M., Claypool, S.M.* and Sesaki, H.* (2012) Role for two conserved intermembrane space proteins, Ups1p and Ups2p, in intra-mitochondrial phospholipid trafficking.  J. Biol. Chem., 287, 15205-15218. *Co-corresponding authors.
12. Trushina, E., Nemutlu, E., Zhang, S., Christensen, T., Camp, J., Mesa, J., Siddiqui, A., Tamura, Y., Sesaki, H., Wengenack, T.M., Dzeja, P.P. and Poduslo, J.F.* (2012) Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease. PLoS One, 7, e32737.
11. Zhang, Z., Wakabayashi, N., Wakabayashi, J., Tamura, Y., Song, W.J., Sereda, S., Clerc, P., Polster, B.M., Aja, S.M., Pletnikov, M.V., Kensler, T.W., Shirihai, O.S., Iijima, M., Hussain, M.A. and Sesaki, H.* (2011) Te dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells. Mol. Biol. Cell, 22, 2235-2245.
10. Tamura, Y., Iijima M., and Sesaki H.* (2010) Mdm35p imports Ups proteins into te mitochondrial intermembrane space by functional complex formation. EMBO J., 29, 2875- 2887.
9. Harada, Y., Tamura, Y., and Endo. T.* (2010) Identification of yeast Art5 as a multicopy suppressor for te mitochondrial translocator maintenance protein Tam41. Biochem. Biophys. Res. Commun., 392, 228-233.
8. Wakabayashi, J., Zhang, Z., Wakabayashi, N., Tamura, Y., Fukaya, M., Kensler, T. W., Iijima, M., and Sesaki, H.* (2009) Te dynamin-related GTPase Drp1 is required for embryonic and brain development in mice.  J. Cell Biol., 186, 805-816.
7. Tamura, Y., Endo, T., Iijima, M., and Sesaki, H.* (2009) Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria.  J. Cell Biol., 185, 1029-1045.
6. Tamura, Y., Harada, Y., Shiota, T., Yamano, K., Watanabe, K., Yokota, M., Yamamoto, H., Sesaki, H. and Endo, T.* (2009) Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import.  J. Cell Biol., 184, 129-141.
5. Dunn, C.D., Tamura, Y., Sesaki, H. and Jensen, R.E.* (2008) Mgr3p and Mgr1p are adaptors for te mitochondrial i-AAA protease complex. Mol. Biol. Cell, 19, 5387-5397.
4. Tamura, Y.†, Harada, Y.†, Yamano, K., Watanabe, K., Ishikawa, D., Ohshima, C., Nishikawa, S., Yamamoto, H. and Endo, T.* (2006) Identification of Tam41 maintaining integrity of te TIM23 protein translocator complex in mitochondria. J. Cell Biol., 174, 631-637. †Equal contribution.
3. Yamamoto, H., Momose, T., Yatsukawa, Y., Ohshima, C., Ishikawa, D., Sato, T., Tamura, Y., Ohwa, Y. and Endo, T.* (2005) Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across te inner membrane. FEBS Lett., 579, 507-511.
2. Ishikawa, D., Yamamoto, H., Tamura, Y., Moritoh, K. and Endo, T.* (2004) Two novel proteins in te mitochondrial outer membrane mediate beta-barrel protein assembly. J. Cell Biol., 166, 621-627.
1. Yamamoto, H., Esaki, M., Kanamori, T., Tamura, Y., Nishikawa, S. and Endo, T.* (2002) Tim50 is a subunit of te TIM23 complex that links protein translocation across te outer and inner mitochondrial membranes. Cell, 111, 519-528.
9. Tamura Y. Kawano S. and  Endo T*. (2020) Lipid homeostasis in mitochondria.  Biol Chem., 401(6-7):821-833. doi: 10.1515/hsz-2020-0121.
8. Tamura Y.* Kawano S. and  Endo T. (2018) Organelle contact zones as sites for lipid transfer,  J. Biochem.,165(2), ,115–123 (DOI:  10.1093/jb/mvy088).
7. Endo T. and  Tamura Y. Kawano S. (2018) Phospholipid transfer by ERMES components.  Aging. 10, 139-201 (DOI:  10.18632/aging.101434).
6. Endo T. and  Tamura Y. (2018) News and Views;  Shuttle mission in te mitochondrial intermembrane space.  EMBO J. e98993 (DOI 10.15252/embj.201898993).
5. Tamura Y.* Sesaki H. and Endo T. (2014) Phospholipid transport via mitochondria. Traffic. 15, 933-945.
4. Zhang Q., Tamura Y., Roy M., Adachi Y., Iijima M., Sesaki H.* (2014) Biosynthesis and Roles of Phospholipids in Mitochondrial Fusion, Division and Mitophagy. Cell. Mol. Life Sci. 71, 3767-78.
3. Tamura, Y.* and Endo, T. (2013) Unveiling te last missing link of te cardiolipin synthetic pathway in mitochondria. Aging, 5, 392-393. (Editorial)
2. Tamura, Y., Itoh, K. and Sesaki, H.* (2011). SnapShot: Mitochondrial dynamics. Cell 145,1158-1158e1.
1. Cerveny, K.L., Tamura, Y., Zhang, Z., Jensen, R.E. and Sesaki, H.* (2007) Regulation of mitochondrial fusion and division. Trends Cell Biol., 17, 563-569.
7. 田村康(2022)ミトコンドリアを介したオルガネラコンタクトサイト,腎臓内科,Vol. 15, No. 5, 582-588
6. 田村康,田代晋也(2022)クローズアップ実験法,Split−GFPプローブを用いた生細胞におけるオルガネラコンタクトサイトを可視化・定量化する技術,実験医学 Vol. 40 No.9(6月号), 1449-1457
4. 田村康,河野慎,遠藤斗志也(2019)ミトコンドリアを介した脂質輸送と代謝,実験医学(増刊)ミトコンドリアと疾患・老化,Vol. 37 No.12, 37-44.
3. 田村康,河野慎,遠藤斗志也(2018)ミトコンドリアと小胞体間のオルガネラコンタクト,生体の科学 第69巻 第6号 2018年 特集:細胞高次機能をつかさどるオルガネラコミュニケーション
2. 田村康,河野慎,遠藤斗志也(2018)ミトコンドリアと小胞体のクロストーク,月刊「細胞」2018年 7月号 オルガネラのバイオロジー 最前線 Te leading edge of organelle biology
1. 田村康,遠藤斗志也(2013)Tam41はミトコンドリアにおけるカルジオリピン合成に必要なCDP-ジアシルグリセロール合成酵素である,ライフサイエンス新着論文レビュー (First Author’s) http://first.lifesciencedb.jp/archives/7035
3. Tamura Y.,* Kojima R., Endo T. (2019) Advanced In Vitro Assay System to Measure Phosphatidylserine and Phosphatidylethanolamine Transport at ER/Mitochondria Interface. In: Drin G. (eds) Intracellular Lipid Transport. Methods in Molecular Biology, vol 1949. Humana Press, New York, NY
2. Tamura Y.* and Endo T. (2017) Role of intra- and inter-mitochondrial membrane contact sites in yeast phospholipid biogenesis, Organelle Contact Sites: From Molecular Mechanism to Disease, Advances in Experimental Medicine and Biology (ed Mitsuo Tagaya, Thomas Simmen), Springer. DOI: 10.1007/978-981-10-4567-7
1. Tamura, Y., Iijima, M., and Sesaki, H. (2009). Mitochondrial dynamics: fusion and division, In Te Handbook of Cell Signaling (ed. Ralph Bradshaw and Edward Dennis), Elsevier, Inc.
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