Common Cold
Common Cold
[Three large viruses hang in the air in front of Cueball. The one closest to Cueball looks a bit like the virus causing the corona pandemic, although it is made clear it is not this type of virus. The other two are put together in small circles. The one behind the corona-like virus has 7 small circles, four in a group, one above and two below. The other has three circles. They are not so closely knit together, and may instead represent three smaller viruses rather than one large. The corona type virus addresses Cueball with a starburst above it indicating it speaks the lines above.] Corona-like virus: Hi there! We're the viruses that cause the common cold. Corona-like virus: This handwashing... Corona-like virus: It stops when this is all over, right?
[Same setting in a slimmer panel.] Corona-like virus: It's just, it's making things really hard for us, too. Corona-like virus: Maybe we could make a deal?
[Same setting in a frame-less panel. The large virus also speaks as indicated with a starburst above it.] Large virus: We won't kill you! Large virus: We just want to get back in your throat and make you feel gross now and then. Corona-like virus: Show us some mercy?
[Zoom in on Cueball, beat panel.]
[In the close-up of Cueball, he lifts his hand up, which has been balled into a fist. He is emphatic in his reply.] Cueball: No.

This comic is another in a series of comics related to the COVID-19 pandemic .
This comic with talking viruses was followed by a comic debating if viruses are Alive Or Not ?
Many of the measures humans have undertaken to fight SARS-CoV-2, such as careful hand-washing and sanitizing of frequently-touched surfaces, are effective against most pathogens. Hence, one of the ironic silver linings of the coronavirus pandemic is that the aggressive implementation of these measures is likely to slow the spread, not only of SARS-CoV-2 but of many common illnesses. If these measures become long-term social expectations, they may improve public health long after the current pandemic has passed.
Hand-washing with soap is a particularly effective way to disable coronaviruses and influenza viruses, which have a viral envelope .
Most common colds are caused by a rhinovirus , a non-encapsulated virus that is not as sensitive to soap. Nonetheless, proper and frequent hand-washing appears to reduce the spread of most viruses, by removing biological residue which harbors the virus. Hence, more aggressive hygiene is likely to have at least some impact on most easily transmissible diseases.
In this strip, Randall addresses the matter from the point of view of viruses. Specifically, those that cause the common cold , imagining them as sentient entities, with spreading infection as their conscious goal. Much like in 2287: Pathogen Resistance , the humor comes from the perspective flip, where health measures intend to protect us are seen by the pathogens as terrifying attacks. In this strip, the cold viruses become aware that more aggressive hygiene measures are putting them at risk, and hope to negotiate with humanity, on the grounds that, unlike SARS-CoV-2, they are rarely fatal. Their hope seems to be that, once the current pandemic is brought under control, humanity will abandon these measures, and allow them to freely spread, once again.
Cueball's adamant refusal likely reflects Randall's hope that this pandemic will result in lasting changes, slowing the spread of all diseases, including those which are merely very unpleasant, as opposed to actually fatal. By treating this as a conscious battle, people may be more inclined to be vigilant, and not allow the enemy any opportunity to recover.
While colds are unlikely to kill otherwise healthy humans, they still cause symptoms that can be painful, even debilitating, in the short term. Previous strips made reference to the miserable nature of the disease.  In December 2015, Randall released both 1612: Colds and 1618: Cold Medicine .
The what if? book previously dealt with the plausibility of eliminating the common cold through aggressive physical distancing alone. The section in that book concluded that total elimination would be impractical. However, the current situation suggests that minimizing the spread of disease by careful hygiene measures is realistic.
In the title text, Randall mentions a virus with the name metapneumovirus . He states that this is easily the common cold virus with the coolest name. But that does not mean it warrants our sympathy (as it is present in up to 40% of colds, and can be deadly in vulnerable populations). And he finishes by stating that "Colds suck. No mercy." So Randall would not be sorry to see the common cold eliminated, or at least substantially contained, by our coronavirus precautions.
[Three large viruses hang in the air in front of Cueball. The one closest to Cueball looks a bit like the virus causing the corona pandemic, although it is made clear it is not this type of virus. The other two are put together in small circles. The one behind the corona-like virus has 7 small circles, four in a group, one above and two below. The other has three circles. They are not so closely knit together, and may instead represent three smaller viruses rather than one large. The corona type virus addresses Cueball with a starburst above it indicating it speaks the lines above.] Corona-like virus: Hi there! We're the viruses that cause the common cold. Corona-like virus: This handwashing... Corona-like virus: It stops when this is all over, right?
[Same setting in a slimmer panel.] Corona-like virus: It's just, it's making things really hard for us, too. Corona-like virus: Maybe we could make a deal?
[Same setting in a frame-less panel. The large virus also speaks as indicated with a starburst above it.] Large virus: We won't kill you! Large virus: We just want to get back in your throat and make you feel gross now and then. Corona-like virus: Show us some mercy?
[Zoom in on Cueball, beat panel.]
[In the close-up of Cueball, he lifts his hand up, which has been balled into a fist. He is emphatic in his reply.] Cueball: No.
