Sigh
Sigh
[Cueball is standing behind Megan, who's sitting and watching TV.] Cueball: Hey, is that Downtown Abbey ? What town is it in the downtown of, anyway? Megan: *siiiiiiigh* Cueball: — girl look at that body.
[Caption below the panel:] We should thank LMFAO for giving us such a great way to respond to exasperated sighs.

Cueball is mispronouncing the name of the British TV show, also available in the US, Downton Abbey . Mispronouncing the title as DownTOWN Abbey causes Megan to sigh because it is such a common and stupid mistake to fans of the show. Mispronouncing the title changes the meaning from being about the eponymous Yorkshire Country Estate (pronounced doun -tuhn ab -ee /ˌdaʊntən ˈæbi/) to being about a monastery in the midst of a large city (incorrectly pronounced doun-toun ab -ee /ˈdaʊnˌtaʊn ˈæbi/). In the UK the CBD, the Central Business District (the big middly bit), is simply called the "city centre".
LMFAO is a ubiquitous group in the US on radio, TV and even strange commercials with rodents riding in cars with their song, Party Rock Anthem . However, this comic is a reference to another one of their songs, "Sexy And I Know It." The relevant lyrics are:
sigh … girl look at that body sigh … girl look at that body sigh … girl look at that body ah-ah, I work out!
The title text is referring to the multiple uses of that lyric throughout the song, creating a steady rhythm.
[Cueball is standing behind Megan, who's sitting and watching TV.] Cueball: Hey, is that Downtown Abbey ? What town is it in the downtown of, anyway? Megan: *siiiiiiigh* Cueball: — girl look at that body.
[Caption below the panel:] We should thank LMFAO for giving us such a great way to respond to exasperated sighs.
