Active Ingredients Only
Active Ingredients Only
[A picture of a pack of cold medicine. At the top there is a large advert in three lines. In a black line, to the right of the advert, white text states what kind of medicine is in the pack. Below to the left is a square frame listing ingredients. Most of the text inside this frame is unreadable scribbles. To the right of the frame is another advert inside a black frame. On the side of the box are also unreadable scribbles, both at the top and down next to the ingredients list. At the bottom of the box it can be seen how the pack can open up.] Active Ingredients Only TM We're not here to waste your time®
Cold Medicine
Active ingredients [Six lines of scribbles, with first a name, then a statement in brackets and finally a column right of this with a short line of scribbles.]
Inactive ingredients None
No binders!

Commercial medicine typically has one (or a few) "Active" ingredient and many "Inactive" ingredients. Active ingredients are the actual medicine, while inactive ingredients -- such as preservatives, dyes, or binders -- are added to dilute the active ingredient to a healthy level and help the body absorb the dose of active ingredient.
Randall thus presents a pack of cold medicine that has "Active Ingredients Only", which is the name of the brand as can be seen since it has "™" after the name (the unregistered trademark symbol). It has six active ingredients and no inactive ingredients. This is a spoof of the current trend of advertising food as containing "no additives and no preservatives".
Cold medicines are commonly packaged in blister packs, with each dose contained separately, and vegans commonly open up gelatin capsules and discard the capsule, ingesting only the contents of the pill (note that this may not be safe . Please consult your pharmacist or doctor before doing this).  By removing the inactive ingredients of the gelatin and the requirement to open it up, the slogan We're not here to waste your time , is justified.  This slogan is also trademarked.
The slogan is a registered trademark (®) while the product name is a common law trademark. This means that the slogan likely stays the same, while the product name changes from time to time.
In the title text, the medicine company promises their product "Contains the active ingredients from all competing cold medicines, plus the medicines for headaches, arthritis, insomnia, indigestion, and more, because who wants THOSE things?" This may be  be a follow-up (or a wish from Randall) after 1618: Cold Medicine , where Cueball wishes to try all possible types of cold medicine at once. The provided justification for combining all these medications is simple: These medicines cure unpleasant symptoms, so taking them all must be a good thing. What this ignores is that taking medicine intended to solve symptoms one doesn't have can be potentially harmful, and would likely be unavoidable for this product's consumers unless they are suffering from all these conditions simultaneously. Furthermore, mixing medications can often lead to unintended reactions and side effects, and is typically advised against.
Another joke is that popular cold medicines contain no antiviral ingredients at all, and treat symptoms only -- while it might make your runny nose less runny, it will do just as much to clear the rhinovirus causing your runny nose as a sugar pill. This part of the comic may be a follow-up to 1526: Placebo Blocker , where a sugar pill is offered to treat a headache.
A secondary joke is by claiming the active ingredients from all "competing" cold medicines, the company producing this "Active Ingredients Only" may choose whom they say they are competing against.  Some cold medications treat only pain and fever, for example, and do nothing for cough, congestion, runny nose and sneezing.  Doctors recommend medicines which aid for the particular symptoms of the cold one is experiencing.
[A picture of a pack of cold medicine. At the top there is a large advert in three lines. In a black line, to the right of the advert, white text states what kind of medicine is in the pack. Below to the left is a square frame listing ingredients. Most of the text inside this frame is unreadable scribbles. To the right of the frame is another advert inside a black frame. On the side of the box are also unreadable scribbles, both at the top and down next to the ingredients list. At the bottom of the box it can be seen how the pack can open up.] Active Ingredients Only TM We're not here to waste your time®
Cold Medicine
Active ingredients [Six lines of scribbles, with first a name, then a statement in brackets and finally a column right of this with a short line of scribbles.]
Inactive ingredients None
No binders!
