title: Midazolam - Neonatal Intensive Care Drug Manual
text: Midazolam
  Revision Date : 16-11-2020
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  Approved: TC, KOH
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  Alert
  High risk medication causing significant patient harm when used in error.
  Indication
  Sedation during ventilation or procedure.
  Treatment of refractory seizure.
  Action
  Intensify the physiological inhibitory mechanisms mediated by gamma-aminobutyric acid (GABA) by accumulation and occupation of benzodiazepine receptors. Anti-anxiety properties are related to increasing the glycine inhibitory neurotransmitter.
  Drug type
  Short acting benzodiazepine.
  Trade name
  Hypnovel, Midazolam Alphapharm,, Midazolam Pfizer,, Midazolam-Baxter, B.Braun Midazolam, Midazolam Accord, Midazolam Apotex.
  Presentation
  5 mg/mL, 5mg/5mL, 150mg/10mL and 15mg/3mL ampoules used for IV and oral use
  Dose
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