title: Dosage/Interval - Neonatal Intensive Care Drug Manual
text: Term neonate (37+0 weeks and over)
  PO: Loading dose of 10 microgram/kg/dose 8-hourly for 3 doses, followed by
  Maintenance dose of 8 microgram/kg/dose daily (may increase up to 12 microgram/kg/day according to therapeutic drug monitoring and in consultation with cardiologist)
  IV: Loading and maintenance doses are 75% of oral dose.
  Preterm neonate:
  PO: Loading dose of 10 microgram/kg/dose 8-hourly for 3 doses, followed by
  Maintenance dose of 5–7.5 microgram/kg/dose daily (up to 12 microgram/kg/day according to therapeutic monitoring and in consultation with cardiologist)
  IV: Loading and maintenance doses are 75% of oral dose.
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