title: Beta-blocker overdose - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 248/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Beta-blocker overdose: Refer to evidence summary.
  Dose adjustment
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  Therapeutic hypothermia – No information.
  ECMO – NO information.
  Renal impairment – No information.
  Hepatic impairment – No information.
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  Maximum dose
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  Maximum stat dose: 1 mg (1000 microgram)
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  Total cumulative dose
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  Route
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  IV, IM, SC
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  Preparation
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  IV bolus/IM/SC:
  Reconstitute 1 mg (1000 microgram) glucagon vial with 1 mL of diluent provided (water for injection) to make a 1 mg/mL (1000 microgram/mL) solution.
  IV infusion
  SINGLE STRENGTH infusion:
  Infusion Strength
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  Prescribed amount
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  1 mL/hour = 10 microgram/kg/hour
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  0.5 mg/kg (0.5 mL/kg) glucagon to make up to 50 mL
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  Add 1 mL of diluent provided (water for injection) to the 1 mg vial (1000 microgram of glucagon) to make a 1mg/mL solution.
  FURTHER DILUTE
  Draw up 0.5 mL/kg (0.5 mg/kg of glucagon) of the above solution and make up to a final volume of 50 mL with glucose 5% to make a final concentration of 10 microgram/kg/mL.
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