title: Contraindications - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 535/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Contraindications
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  Resonium A and Calcium Resonium should not be administered orally to neonates and is contraindicated in neonates with reduced gut motility (e.g. post-operatively or drug induced).(2)
  History of hypersensitivity to polystyrene sulfonate resins.
  Serum potassium levels less than 5 mmol/L.
  Obstructive bowel disease.
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  Precautions
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  Hypercalcaemia, hyperparathyroidism: avoid calcium resin.
  Congestive heart failure, hypernatraemia, sodium overload: avoid sodium resin
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  Drug interactions
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  Not applicable
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  Adverse reactions
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  Electrolyte imbalances: Hypokalaemia, hypernatraemia, hypocalcaemia, hypercalcaemia, hypomagnesaemia
  Water overload
  Gastrointestinal: Perforation, haemorrhage, necrotising enterocolitis
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  Compatibility
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  Not applicable
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  Incompatibility
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  Not applicable
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  Stability
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  Suspensions of the resin should be freshly prepared and not stored beyond 24 hours.
  Once reconstituted, Resonium A and Calcium Resonium is a cream to light brown coloured suspension in which small white particulates may remain visible.
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  Storage
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  Store below 30°C.
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  Excipients
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  Resonium A and Calcium Resonium: Saccharin sodium and vanillin.
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