title: Adverse Reactions - Neonatal Intensive Care Drug Manual
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  Neonatal Intensive Care Drug Manual
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  bet | 300/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Adverse Reactions
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  If adverse reactions occur, the first response should be to stop the infusion, then notify Medical Officer.
  Severe reactions are uncommon especially in neonates. In older patients are most likely to occur during the first infusion, but may occur subsequently.
  Anaphylactic reactions are rare: urticaria, angioedema, bronchospasm and hypotension. Anaphylactic reactions may require oxygen, adrenaline (epinephrine) and steroids depending on severity of the reaction.
  More common reactions are: flushing, fever, headache, pallor, shivering and tachycardia.
  Other reported reactions: dyspnoea, chest tightness, tachycardia or hypotension without anaphylaxis, transient haemolytic anaemia, abdominal pain and renal failure.
  Milder reactions often resolve after the infusion has been stopped. If so, after discussion with medical staff, the infusion may be recommenced at a slower rate after at least 15 minutes.
  Subsequent infusions should be commenced and escalated at a slower rate.
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  Compatibility
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  Sodium chloride 0.9% for priming and flushing. Others not tested.
  Administer through a separate line.
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