title: Drug Interactions - Neonatal Intensive Care Drug Manual
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  Neonatal Intensive Care Drug Manual
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  bet | 569/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Drug Interactions
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  Sotalol clearance is reduced by alcohol.
  Other interactions include: Insulin and oral hypoglycaemics (hypo- and hyperglycaemia); calcium channel blockers (hypotension, bradycardia, heart failure); clonidine (hypertension); drugs that prolong the Qtc interval (quinolone antibiotics).
  Sotalol interactions have been reported with other antiarrhythmics: Class IA agents, disopyramide and quinidine; class IB, tocainide, mexiletine and lignocaine; class IC, flecainide and propafenone; class III, amiodarone; and class IV antiarrhythmic agents. Concomitant use of sotalol with these agents and with other beta-blocking drugs is not recommended.
  Concomitant use of sotalol and diuretics may increase the cardiotoxicity.
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