title: Nystatin - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 402/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Nystatin
  Revision Date : 24-12-2020
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  Approved : TC, KOH
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  Alert
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  The Antimicrobial Stewardship Team listed this drug under the following category: Unrestricted.
  Nystatin is not suitable for the treatment of invasive fungal disease.
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  Indication
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  1) Prophylaxis in infants at high risk for invasive fungal infections. Criteria for prophylaxis should be determined by local policy. Indications may include: Infants ≤ 28 weeks gestation at birth or < 1000 g birth weight or larger infants with risk, factors including use of broad spectrum antibiotics, having a central venous access device, (PICC/UVC/CVC), receiving parenteral nutrition or inhaled steroids.
  2) Treatment of mucocutaneous candidiasis.
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  Action
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  Fungicidal agent which works by combining with the sterol elements of fungal cell membranes, causing cell death by producing increased cell wall permeability.
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