title: Route
    
  Dose - Neonatal Intensive Care Drug Manual
text: Loading dose: 20 mg/kg
  Maintenance dose: Start 12 hours after loading dose.
  First 7 days of life:
  Term infants: 2.5 mg/kg/dose every 12 hours (range 4–8 mg/kg/day)
  Preterm infants: 2.5 mg/kg/dose every 24 hours. Titrate as per serum concentrations.
  8–30 days:
  Term infants: 2.5 mg/kg/dose every 8 hours (range 4–8 mg/kg/day)
  Preterm infants: 2.5 mg/kg/dose every 12 hours. Titrate as per serum concentrations.
  Beyond 30 days:
  Term infants: 2.5 mg/kg/dose every 6 hours
  Preterm infants: 2.5 mg/kg/dose every 8 hours. Titrate as per serum concentrations.
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