title: Practice points - Neonatal Intensive Care Drug Manual
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  Neonatal Intensive Care Drug Manual
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  bet | 464/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Practice points
  References
  Painter MJ, Scher MS, Stein AD, Armatti S, Wang Z, Gardiner JC, Paneth N, Minnigh B, Alvin J. Phenobarbital compared with phenytoin for the treatment of neonatal seizures. The New England journal of medicine. 1999; 341:485-9.
  Pathak G, Upadhyay A, Pathak U, Chawla D, Goel SP. Phenobarbitone versus phenytoin for treatment of neonatal seizures: an open-label randomized controlled trial. Indian pediatrics. 2013; 50:753-7.
  Slaughter LA, Patel AD, Slaughter JL. Pharmacological treatment of neonatal seizures: a systematic review. Journal of child neurology. 2013; 28:351-64.
  Neonatal seizures. eTG complete. [Internet] Melbourne: Therapeutic Guidelines Limited; 2016.
  Piper JD, Hawcutt DB, Verghese GK, Spinty S, Newland P, Appleton R. Phenytoin dosing and serum concentrations in paediatric patients requiring 20 mg/kg intravenous loading. Archives of disease in childhood. 2014; 99:585-6.
  Nolan SJ, Marson AG, Weston J, Tudur Smith C. Carbamazepine versus phenytoin monotherapy for epilepsy: an individual participant data review. The Cochrane database of systematic reviews. 2015; 8:CD001911.
  Williams A, Martin J, Lucas C, Bolisetty S. Rational dosing of medications for neonates receiving treatment with therapeutic hypothermia for hypoxic-ischaemic encephalopathy: A literature review with evidence based recommendations (thesis).
  Dillman NO, Messinger MM, Dinh KN, et al. Evaluation of the Effects of Extracorporeal Membrane Oxygenation on Antiepileptic Drug Serum Concentrations in Pediatric Patients. J Pediatr Pharmacol Ther. 2017; 22(5):352‐357.
  Loughnan PM, Greenwald A, Purton WW, Aranda JV, Watters G, Neims AH. Pharmacokinetic observations of phenytoin disposition in the newborn and young infant. Archives of disease in childhood. 1977; 52:302-9.
  Al Za'abi M, Lanner A, Xiaonian X, Donovan T, Charles B. Application of routine monitoring data for determination of the population pharmacokinetics and enteral bioavailability of phenytoin in neonates and infants with seizures. Therapeutic drug monitoring. 2006; 28:793-9.
  Frey OR, von Brenndorff AI, Probst W. Comparison of phenytoin serum concentrations in premature neonates following intravenous and oral administration. The Annals of pharmacotherapy. 1998; 32:300-3.
  Wolf GK, McClain CD, Zurakowski D, Dodson B, McManus ML. Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2006;7:434-9; quiz 40.
  ter Heine R, van Maarseveen EM, van der Westerlaken MM, Braun KP, Koudijs SM, Berg MJ, Malingre MM. The quantitative effect of serum albumin, serum urea, and valproic acid on unbound phenytoin concentrations in children. Journal of child neurology. 2014; 29:803-10.
  Kiang TK, Ensom MH. A Comprehensive Review on the Predictive Performance of the Sheiner-Tozer and Derivative Equations for the Correction of Phenytoin Concentrations. Ann Pharmacother. 2016 Apr; 50(4):311-25.
  Trissels 2 compatibility database, Phenytoin monograph, accessed via Micromedex 26/06/2015
  Pfizer Australia Pty Ltd, Dilantin product information, 2013
  Hospira Pty Ltd, DBL Phenytoin Injection BP, 2012
  St. Louis EK, Gidal BE, Henry TR, Kaydanova Y,Krumholz A, McCabe PH, et al. Conversions between monotherapies in epilepsy: Expert consensus. Epilepsy and Behaviour 2007; 11:222-234.
  Australian Injectable Drugs Handbook, 6th Edition, Society of Hospital Pharmacists of Australia 2014.
  Original version Date: 27/6/2016
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  Author: Neonatal Medicines Formulary Consensus Group
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  Current Version number: 4
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  Version Date: 16/12/2020
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  Risk Rating: Low
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  Due for Review: 16/12/2025
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  Approval by: DTC
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  Approval Date: TBA
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