title: Glucagon - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 247/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Glucagon
  Revision Date : 15-12-2020
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  Approved : TC, KOH
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  Alert
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  Do not run through filter or TPN
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  Indication
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  Management of neonatal hypoglycaemia:
  Refractory to intravenous glucose infusions;
  When glucose infusion is unavailable.
  Management of hyperinsulinaemic hypoglycaemia (e.g. congenital hyperinsulinism).
  Adjunctive treatment of beta-blocker overdose.
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  Action
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  Stimulates hepatic gluconeogenesis and glycogenolysis. Glucagon has a positive inotropic action.
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  Drug type
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  Polypeptide hormone – hyperglycaemic agent
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  Trade name
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  GlucaGen HypoKit 1 mg/mL
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  Presentation
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  1 mg/mL vial.
  1 unit of glucagon = 1 mg (1000 microgram) glucagon
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  Dose
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  IV bolus/IM/SC
  200 microgram/kg/dose. Do not exceed 1 mg/dose. IV glucose is to be administered as soon as possible.
  IV infusion
  5–20 microgram/kg/hour.
  Consider starting dose of 20 microgram/kg/hour and decrease carefully, monitoring blood glucose, until the minimum effective dose is reached.
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