title: Continuous infusion - Neonatal Intensive Care Drug Manual
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  Neonatal Intensive Care Drug Manual
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  bet | 528/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Continuous infusion
  Use the 50 mg/2 mL injection (Zantac) for IV infusion: Draw up 0.2 mL/kg (5 mg/kg of ranitidine) and make up to 50 mL with sodium chloride 0.9%, glucose 5% or glucose 10%. Infuse at a rate of 1 mL/hour = 100 microg/kg/hour
  Ranitidine Sandoz 50 mg/5 mL injection has no stability data at room temperature and therefore not recommended for IV infusion.
  Administration
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  IV bolus: Administer dose over at least 5 minutes.
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  Monitoring
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  Nil
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  Contraindications
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  Patients with known hypersensitivity to any component of the preparation.
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  Precautions
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  Caution should be observed in patients with hepatic dysfunction since ranitidine is metabolised by the liver. Ranitidine is excreted via the kidneys. In the presence of severe renal impairment, plasma concentrations of ranitidine are increased and elimination prolonged. Bradycardia — ensure recommended rates of administration as not exceeded.
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