title: Erythromycin - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 192/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Erythromycin
  Revision Date : 15/12/2020
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  Approved : TC, KOH
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  Alert
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  Risk of infantile hypertrophic pyloric stenosis is significantly higher in neonates treated with erythromycin.16
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  Indication
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  Pertussis – post-exposure prophylaxis and treatment (azithromycin is recommended).
  Chlamydial conjunctivitis and pneumonia
  Treatment of other susceptible bacterial infections in penicillin-allergic infants
  Prokinetic agent for gastrointestinal dysmotility (routine use not recommended)
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  Action
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  Inhibits protein synthesis by attaching to the 50S subunit of the bacterial ribosome in susceptible organisms.
  Motilin receptor agonist.
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  Drug Type
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  Macrolide antibiotic.
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  Trade Name
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  E-Mycin Syrup, EES Granules
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  Presentation
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  200 mg/5 mL suspension (granules for reconstitution), 100 mL
  400 mg/5 mL suspension (granules for reconstitution), 100 mL
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