title: Maximum daily dose - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 298/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Maximum daily dose
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  2 g/kg/day.
  Enterovirus infection: 2.5 g/kg/day
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  Route
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  Intravenous.
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  Preparation/Dilution
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  Obtain written consent from parent or guardian.
  All opened bottles must be used immediately.
  Do not shake bottles to avoid foaming.
  A ‘peel-off’ identification label with Batch Number and Expiry Date is to be placed on the patient’s Blood Component order form.
  Allow preparation to reach room temperature and inspect for turbidity or sediments. If seen, return to Blood Bank.
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  Administration
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  Infusion rate: 0.5 mL/kg/hour for 60 minutes; then 1 mL/kg/hour for next 60 minutes; 2 mL/kg/hour for next 60 minutes; then 4 mL/kg/hour (at a maximum rate of 25 mL/hour).
  To be checked by two Registered Nurses.
  Requires a surgically clean procedure.
  Given via intravenous cannula, central line, long line or port.
  Administered by infusion pump.
  A blood filter is not required, but may be used.
  Sodium chloride 0.9% may be used as a flush at the end of the infusion.
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  Monitoring
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  Vital sign monitoring of temperature, heart rate, respiratory rate and blood pressure to be recorded before commencement of infusion.
  If the patient is unwell or there are any concerns particularly regarding the baseline observations, the medical officer should be contacted before the infusion commences.
  Vital signs (temperature, heart rate, respiratory rate) should then be checked and recorded:
  Within 15 minutes after the start of the infusion;
  Hourly during the infusion;
  At the end of the infusion.
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