title: Adverse reactions - Neonatal Intensive Care Drug Manual
text: Hyperkalaemia: Can develop rapidly and asymptomatically and is potentially fatal.
  Pain or phlebitis may occur.
  Cardiovascular: Hypotension, cardiac depression, arrhythmias and heart block.
  ECG abnormalities: - Disappearance of P wave, widening and slurring of QRS complex, changes of the ST segment, tall peaked T waves.
  Gastrointestinal: Vomiting, diarrhoea and abdominal discomfort.
  Other: Listlessness, flaccid paralysis.
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  Compatibility
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  Fluids: Sodium chloride 0.9%, sodium chloride 0.45%, Hartmann’s, Ringer’s, pre-mixed amino-acid formulations(6). Glucose containing solutions, but NOT PREFFERED as glucose may further decrease serum potassium level.
  Y-site: Do not add other drugs to pre-mixed potassium chloride bags.
  Aciclovir, aminophylline, amiodarone, ampicillin, atracurium, atropine, azathioprine, aztreonam, calcium gluconate, caspofungin, cefazolin, cefotaxime, cefoxitin, ceftazidime, ceftriaxone, clindamycin, dexamethasone, dexmedetomidine, digoxin, dopamine, ephedrine sulfate, fentanyl, fluconazole, furosemide, ganciclovir, gentamicin, glyceryl trinitrate, heparin, hydrocortisone, insulin, labetalol, lidocaine, linezolid, magnesium sulfate, metoclopramide, midazolam, milrinone, morphine, neostigmine, noradrenaline, paracetamol, piperacillin-tazobactam, ranitidine, remifentanil, sodium bicarbonate, tobramycin, vancomycin, verapamil, zidovudine.(6)
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