title: Contraindications - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 563/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Contraindications
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  Oral: Infants who are not taking any enteral nutrition, acute gastrointestinal illness including ileus, necrotising enterocolitis, intestinal obstruction.
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  Precautions
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  Impaired renal function, cardiac insufficiency, pre-existing oedema with sodium retention.
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  Drug Interactions
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  No information.
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  Adverse Reactions
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  Hypernatraemia, volume overload, congestive heart failure, respiratory distress
  Hyperchloraemia, hypercalciuria
  Disseminated intravascular coagulation (DIC) is associated with inadvertent injections of sodium chloride into blood vessels of the uterus or placenta due to hypernatraemic shock. Not reported in infants.
  Osmotic demyelinating syndrome.
  Fever
  IV site: Extravasation, phlebitis, venous thrombosis.
  Oral: Gastric irritation.
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