title: Dose adjustment - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
  |
  bet | 356/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Dose adjustment
  Maximum dose
  Total cumulative dose
  Route
  IV, IM, Oral, Sublingual, Intranasal.
  Preparation
  IV
  Sedation using 5 mg/1 mL strength
  Infusion strength
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  Prescribed amount
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  1 mL/hour = 1 microgram/kg/minute
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  3 mg/kg midazolam and make up to 50 mL
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  Draw up 0.6 mL/kg (3 mg/kg of midazolam) and add glucose 5%, glucose 10% or sodium chloride 0.9% to make final volume 50 mL. Infuse at a rate of 1 mL/ hour = 1 microgram/kg/minute.
  Sedation using 5mg/5 mL strength
  Infusion strength
  |
  Prescribed amount
  |
  1 mL/hour = 1 microgram/kg/minute
  |
  3 mg/kg midazolam and make up to 50 mL
  |
  Draw up 3 mL/kg (3 mg/kg of midazolam) and add glucose 5%, glucose 10% or sodium chloride 0.9% to make final volume 50 mL. Infuse at a rate of 1 mL/ hour = 1 microgram/kg/minute.
  Seizures using 5 mg/1 mL strength
  Infusion strength
  |
  Prescribed amount
  |
  1mL/hour = 5microgram/kg/minutes
  |
  15mg/kg midazolam and make up to 50mL
  |
  Draw up 3 mL/kg (15 mg/kg of midazolam) and add glucose 5%, glucose 10% or sodium chloride 0.9% to make final volume 50 mL. Infuse at a rate of 1 mL/hour = 5 microgram/kg/minute.
  Seizures using 5 mg/5 mL strength (not to be used for babies over 3.3 Kg)
  Infusion strength
  |
  Prescribed amount
  |
  1mL/hour = 5microgram/kg/minutes
  |
  15mg/kg midazolam and make up to 50mL
  |
  Draw up 15 mL/kg (15 mg/kg of midazolam) and add glucose 5%, glucose 10% or sodium chloride 0.9% to make final volume 50 mL. Infuse at a rate of 1 mL/hour = 5 microgram/kg/minute.
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