title: Contraindications - Neonatal Intensive Care Drug Manual
text: Use with caution in preterm infants and infants with poor myocardial contractility as a sole inotrope/vasopressor.
  Thyrotoxicosis – may cause severe hypertension.
  Ensure adequate circulating blood volume prior to commencement.
  Avoid in hypertension.
  Overdosage may result in severe hypertension, reflex bradycardia, marked increase in peripheral resistance and decreased cardiac output.
  The infusion site should be checked frequently for free flow. Care should be taken to avoid extravasation into the tissues which may cause local necrosis.
  Do not cease infusion abruptly.
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