title: Dosage / Interval - Neonatal Intensive Care Drug Manual
text: Medical officer should prescribe (1) brand of IVIg and the % concentration (e.g. Intragam 10), (2) dose in grams and the volume in mL (e.g. 2 g/20 mL) and (3) Rate of infusion (see Administration section)
  Isoimmunisation:
  1 g/kg (range 0.5–1.5 g/kg) IV. Dose may be repeated in 12–24 hours if required.
  Neonatal alloimmune thrombocytopenia (NAIT):
  1 g/kg IV. Repeat if required.
  Immune thrombocytopenic purpura (ITP):
  1 g/kg IV. Repeat if required.
  Immunodeficiency:
  0.4 g/kg IV (dose should be based on number of infections and trough serum IgG concentration [optimally above 6 g/L, higher if there is bronchiectasis]).
  Neonatal myasthenia gravis:
  1 g/kg IV daily for 2 days (total dose: 2 g/kg). If additional therapy required, titrate against clinical response.[9]
  Severe enterovirus infection/myocarditis or hepatitis:
  2 g/kg IV (up to 2.5 g/kg) as a single dose within 3 days of onset.
  Sepsis/infection (prevention or treatment) – not recommended:
  0.5 to 1 g/kg IV repeated at intervals when required has been used.
  Neonatal haemochromatosis:
  1–2 g/kg/day IV following exchange transfusion in the first 7 days and then 1 g/kg weekly, as required.
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