title: Contraindications - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 471/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Contraindications
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  Hyperphosphataemia, dehydration, severe renal insufficiency, shock.
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  Precautions
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  Hypernatraemia (avoid sodium dihydrogen phosphate).
  Hyperkalaemia (avoid potassium dihydrogen phosphate)
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  Drug Interactions
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  Calcium and magnesium antacids (e.g. acetate, carbonate, citrate, hydroxide etc.) reduce phosphate absorption — separate doses by at least 2 hours.
  Additive effects with other drugs that may prolong QT interval.
  Potassium dihydrogen phosphate preparation may increase the risk of hyperkalaemia when used in conjunction with potassium sparing diuretics (e.g. spironolactone).
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