title: Drug Interactions - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
  |
  bet | 396/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Drug Interactions
  |
  Should be given with close monitoring to patients exposed to monoamine oxidase inhibitors because severe, prolonged hypertension may result.
  |
  Adverse Reactions
  |
  Systemic hypertension especially at higher doses.
  Reflex bradycardia and arrhythmia.
  Tissue necrosis at infusion site with extravasation. [see special comments]
  Renal and digital ischaemia may occur.
  Prolonged administration of any potent vasopressor may result in plasma volume depletion which should be continuously corrected by appropriate fluid and electrolyte replacement therapy.
  |
  Compatibility
  |
  Fluids: Glucose 5%, sodium chloride 0.9% with glucose 5%, sodium chloride 0.9%, lactated Ringer’s solution.
  Y-site: Amiodarone, anidulafungin, bivalirudin, caspofungin, ceftaroline fosamil, cisatracurium, dexmedetomidine, dobutamine, dopamine, doripenem, esmolol, ethanol, haloperidol lactate, heparin sodium, hydrocortisone sodium succinate, labetalol, midazolam, milrinone, morphine sulfate, mycophenolate mofetil, potassium chloride, remifentanil, sodium nitroprusside, tigecycline.
  |
  |
  |
  | |