title: Administration - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 470/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Administration
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  Oral
  Generally avoid administration with feeds (refer to evidence summary section).
  Separate calcium supplements by at least 2 hours.
  IV
  As part of parenteral nutrition fluid – refer to individual parenteral nutrition formulations.
  IV infusion for treatment of acute hypophosphataemia:
  IV sodium dihydrogen phosphate or IV potassium dihydrogen phosphate: Infuse over at least 6 hours. For severe hypophosphataemia infuse over 8–12 hours. Maximum infusion rate of 0.2 mmol/kg/h.
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  Monitoring
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  Phosphate, calcium, magnesium, alkaline phosphatase concentrations are required at least fortnightly or more often if required. Once these concentrations normalise, serum analysis may be performed once monthly for 6 months or at the discretion of the clinician.10
  Urinary calcium and phosphate and Tubular Reabsorption Phosphate (TRP)%, parathormone, and vitamin D concentrations may be useful under certain circumstances .
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