title: Dosage / Interval - Neonatal Intensive Care Drug Manual
text: |
  Neonatal Intensive Care Drug Manual
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  bet | 500/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Dosage / Interval
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  Premedication for endotracheal intubation*
  IV: Start at 1 mg/kg and titrate dose of 2.5 mg/kg to infant response (check eye lash reflex every 10 seconds – average ranging from 1.0 to 3.6 mg/kg.
  Premedication for MIST or InSurE procedures*
  IV 1 mg/kg (maximum 1.5 mg/kg) (CAUTION: Increases the chance of needing non-invasive respiratory support).
  *NOTE: Propofol may be used alone or in combination with other sedatives/analgesics. Reduce propofol dose by 40–60% if combined with other sedatives/analgesics.
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  Maximum daily dose
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  Premedication: 6 mg/kg.
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  Route
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  IV bolus
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  Preparation/Dilution
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  Use undiluted or dilute to a minimum concentration of 2 mg/mL with glucose 5%.
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  Administration
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  Slow IV bolus over at least 20 seconds.
  Do not use filter.20
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  Monitoring
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  Continuous cardiorespiratory monitoring.
  Resuscitation facilities must be readily available.
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