title: Frusemide - Neonatal Intensive Care Drug Manual
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  Neonatal Intensive Care Drug Manual
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  bet | 221/654 | Sana | 03.01.2022 | Hajmi | 1,5 Mb. | | #14803 |
  Frusemide
  Revision Date : 15-12-2020
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  Approved : TC, KOH
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  Alert
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  Indication
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  Heart failure.
  Fluid overload.
  Short-term treatment in infants with or developing chronic lung disease.
  Oliguric renal failure.
  Diuresis renography.
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  Action
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  Potent loop diuretic. Inhibits sodium and chloride absorption in the ascending limb of the loop of Henle and in the proximal and the distal tubules.
  Furosemide causes urinary losses of water, sodium (increases fractional excretion of sodium by 20–25%),2 potassium and chloride. Urinary losses of calcium and magnesium and urinary pH are increased.
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  Drug Type
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  Loop diuretic.
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  Trade Name
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  IV: Furosemide Sandoz Injection, Furosemide-Claris, Lasix High Dose Concentrate, Lasix Solution. [Excipients: Sodium hydroxide, sodium chloride and water for injection].
  Oral: Lasix oral solution. Note: Contains 12.7% v/v alcohol. [Other Excipients: Sorbitol, glycerol, sodium hydroxide, methyl hydroxybenzoate, propyl hydroxybenzoate, quinoline yellow, sunset yellow FCF, orange flavour, purified water]
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  Presentation
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  IV: 20 mg/2 mL, 40 mg/4 mL or 250 mg/25 mL
  Oral: 10 mg/mL, 30 mL
  Note: Commercial preparation “Lasix” contains 12.7% v/v alcohol.
  Non-alcohol containing suspension can be compounded by local pharmacy.
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