Doxorubicin fluorescence is quenched by binding to DNA, and shielded by micelle encapsulation. It is also known to self-quench at high concentrations. In contrast, histone binding amplifies fluorescence. References
External links
 Media related to Doxorubicin at Wikimedia Commons
"Doxorubicin". Drug Information Portal. U.S. National Library of Medicine. "Doxorubicin hydrochloride". Drug Information Portal. U.S. National Library of Medicine.
WFH as % of median reference value is calculated this way:
  
    
      
        
          W
          F
          H
        
        =
        
          
            
              weight of a given child
            
            
              median weight for a given child of that height
            
          
        
        ×
        100
      
    
    {\displaystyle \mathrm {WFH} ={\frac {\mbox{weight of a given child}}{\mbox{median weight for a given child of that height}}}\times 100}
  Cutoff points may vary, but <80% (close to −2 Z-score) is often used.