A Li-ion battery is a kind of flow battery which can be seen in the image on the right. Furthermore, a Li-ion battery is an example of a secondary cell since it is rechargeable. It can both act as a galvanic or electrolytic cell. Li-ion batteries use lithium ions as the solute in the electrolyte which are dissolved in an organic solvent. Lithium electrodes were first studied by G.N. Lewis and F.G. Keyes in 1913. In the following century these electrodes were used to create and study the first Li-ion batteries. Li-ion batteries are very popular due to their great performance. Applications include mobile phones and electric cars. Due to their popularity, much research is being done to reduce the cost and increase the safety of Li-ion batteries. An integral part of the Li-ion batteries are their anodes and cathodes, therefore much research is being done into increasing the efficiency, safety and reducing the costs of these electrodes specifically. Cathodes
In Li-ion batteries the cathode consists of a intercalated lithium compound (a layered material consisting of layers of molecules composed of lithium and other elements). A common element which makes up part of the molecules in the compound is cobalt. Another frequently used element is manganese. The best choice of compound usually depends on the application of the battery. Advantages for cobalt-based compounds over manganese-based compounds are their high specific heat capacity, high volumetric heat capacity, low self-discharge rate, high discharge voltage and high cycle durability.
The renin–angiotensin system may be subsequently activated, because of the decrease in perfusion of juxtaglomerular apparatus, which may result in hypertension. : 554

Nonproliferative
This is characterised by forms of glomerulonephritis in which the number of cells is not changed. These forms usually result in the nephrotic syndrome. Causes include:

Minimal change disease
Minimal change disease is characterised as a cause of nephrotic syndrome without visible changes in the glomerulus on microscopy. Minimal change disease typically presents with  edema, an increase in proteins passed from urine and decrease in blood protein levels, and an increase in circulating lipids (i.e., nephrotic syndrome) and is the most common cause of the nephrotic syndrome in children. Although no changes may be visible by light microscopy, changes on electron microscopy within the glomeruli may show a fusion of the foot processes of the podocytes (cells lining the basement membrane of the capillaries of glomerulus). It is typically managed with corticosteroids and does not progress to chronic kidney disease. : 500 : 550

Focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis is characterised by a sclerosis of segments of some glomeruli. It is likely to present as a nephrotic syndrome. This form of glomerulonephritis may be associated with conditions such as HIV and heroin abuse, or inherited as Alport syndrome. The cause of about 20–30% of focal-segmental glomerulosclerosis is unknown. On microscopy, affected glomeruli may show an increase in hyalin, a pink and homogenous material, fat cells, an increase in the mesangial matrix and collagen.