Ostomy-related complications
Common complications of an ostomy (a common surgery in Crohns disease) are: Mucosal edema, Peristomal dermatitis, Retraction, Ostomy prolapse, Mucosal/skin detachment, Hematoma, Necrosis, Parastomal hernia, and Stenosis. Etiology
The etiology of Crohns disease is unknown. Many theories have been disputed, with four main theories hypothesized to be the primary mechanism of Crohns disease. In autoimmune diseases, antibodies and T lymphocytes are the primary mode of inflammation. These cells and bodies are part of the adaptive immune system, or the part of the immune system that learns to fight foreign bodies when first identified. Autoinflammatory diseases are diseases where the innate immune system, or the immune system we are genetically coded with, is designed to attack our own cells. Crohns disease likely has involvement of both the adaptive and innate immune systems. Autoinflammatory theory
Crohns disease can be described as a multifactorial autoinflammatory disease. The etiopathogenesis of Crohns disease is still unknown. In any event, a loss of the regulatory capacity of the immune apparatus would be implicated in the onset of the disease. In this respect interestingly enough, as for Blaus disease (a monogenic autoinflammatory disease), the NOD2 gene mutations have been linked to Crohns disease. However, in Crohns disease, NOD2 mutations act as a risk factor, being more common among Crohns disease patients than the background population, while in Blaus disease NOD2 mutations are linked directly to this syndrome, as it is an autosomal-dominant disease.
Intravascular papillary endothelial hyperplasia is a rare, benign tumor. It may mimic an angiosarcoma, with lesions that are red or purplish 5-mm to 5-cm papules and deep nodules on the head, neck, or upper extremities. : 592

Pathology
Histopathology Images
See also
List of cutaneous conditions

References


== External links ==