Based on the data of imaging studies that looked at the localization of processing melodies, it can be inferred that the anatomical location of the processes in consistent with the findings that some SD patients have intact melody recognition. Additionally, the neurobiological basis for musical emotion identification implicated the limbic and paralimbic structures in this process. Overall, the results of these studies suggest that the neurobiological basis of musical semantic memory is bilaterally located in the cerebral hemispheres, likely around the fronto-temporal areas of the brain. Unfortunately, due to the lack of studies studying musical semantic memory, conclusions cannot be more specific. Treatment
There is currently no known curative treatment for SD. The average duration of illness is 8–10 years, and its progression cannot be slowed. Progression of SD can lead to behavioral and social difficulties, thus supportive care is essential for improving quality of life in SD patients as they grow more incomprehensible. Continuous practice in lexical learning has been shown to improve semantic memory in SD patients. No preventative measures for SD are recognized. References
Reference 20: Rohani Omar, Julia C. Halistone, and Jason D. Warren, "Semantic Memory for Music in Dementia," Music Perception 29, no. 5 (June 2012):, doi:10.1525/mp.2012.29.5.467.Reference 21:Lise Gagnon, Isabelle Peretz, and Tamàs Fülöp, "Musical structural determinants of emotional judgments in dementia of the Alzheimer type.," Neuropsychology 23, no. 1 (2009): doi:10.1037/a0013790.Reference 22: J. C. Hailstone, R. Omar, and J. D. Warren, "Relatively preserved knowledge of music in semantic dementia," Journal of Neurology, Neurosurgery & Psychiatry 80, no. 7 (2009): doi:10.1136/jnnp.2008.153130.
Hereditary progressive mucinous histiocytosis is a very rare, benign, non-Langerhans cell histiocytosis. An autosomal dominant or X-linked hereditary disease described on the skin, it has been found almost exclusively in women. One case of the disease in a male patient has been reported. See also
Non-X histiocytosis

References


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