The eradication of yellow fever strengthened the relationship between the US and Mexico, which had not been very good in the years prior. The eradication of yellow fever was also a major step toward better global health.In 1927, scientists isolated the yellow fever virus in West Africa. Following this, two vaccines were developed in the 1930s. Max Theiler led the completion of the 17D yellow fever vaccine in 1937, for which he was subsequently awarded the Nobel Prize in Physiology or Medicine. That vaccine, 17D, is still in use, although newer vaccines, based on vero cells, are in development (as of 2018). Current status
Using vector control and strict vaccination programs, the urban cycle of yellow fever was nearly eradicated from South America. Since 1943, only a single urban outbreak in Santa Cruz de la Sierra, Bolivia, has occurred. Since the 1980s, however, the number of yellow fever cases has been increasing again, and A. aegypti has returned to the urban centers of South America. This is partly due to limitations on available insecticides, as well as habitat dislocations caused by climate change. It is also because the vector control program was abandoned. Although no new urban cycle has yet been established, scientists believe this could happen again at any point. An outbreak in Paraguay in 2008 was thought to be urban in nature, but this ultimately proved not to be the case.In Africa, virus eradication programs have mostly relied upon vaccination.
Hence it is not surprising that OWT therapy has not become popular and is very sparingly used across the globe. References
External links
"Levothyroxine". Drug Information Portal. U.S. National Library of Medicine. "Levothyroxine sodium". Drug Information Portal. U.S. National Library of Medicine. "Real-world Evidence from a Narrow Therapeutic Index Product (Levothyroxine) Reflects the Therapeutic Equivalence of Generic Drug Products". U.S. Food and Drug Administration (FDA). 19 November 2020.