Later that year it was independently described as "spun-glass hair" by J.D. Stroud and A.H. Mehregan. The currently used term was coined in the early 1980s. However, the UHS phenotype was recorded well before the first literature report in 1973. A children’s story published in Germany in 1845 detailed a character named “Struwwelpeter” or “Shockheaded Peter,” presumably to describe the frizzy nature of a patient’s hair with UHS. This children’s story was later translated by Mark Twain and the character was instead called “Slovenly Peter.”Evidence of familial transmission of UHS prior to 1973 also comes from case studies. In 1983, Garty et al. described the case of a 2-year-old boy whose father, grandfather, and great-grandfather were all said to have the same condition at a young age—difficulty combing their hair. In 1993, Zanca and Zanca found a book from 1912 that details the observations, made by Le Double and Houssay (in their book “Les Velus”), of people with “mop hair” that does not tolerate combing. Current research
The American Hair Research Society studies hair growth disorders and possible treatments for them. In addition to UHS, these disorders include alopecia areata, telogen effluvium, cicatricial alopecia, female and male pattern hair loss, trichotillomania, and hair shaft defects. The society was founded in 1989 by a group of dermatologists and has grown to include general physicians, scientific researchers, and other collaborative partners to advance research on human hair. It is one of the only non-profit research centers on hair disorders in the Americas.
Acquired idiopathic generalized anhidrosis (AIGA) is characterized by generalized absence of sweating without other autonomic and neurologic dysfunction.AIGA is classified into 3 subgroups: idiopathic pure sudomotor failure (IPSF), sweat gland failure (SGF), and sudomotor neuropathy, with each subgroup presenting a different pathogenesis. Diagnosis
Quantitative sudomotor axon reflex test and microneurography are used in the diagnosis of AIGA. However, these refined methods are mostly used for research purposes and not generally available.Skin biopsy analysis may play a crucial role in the identification of AIGA subgroups. See also
Hypohidrosis

References


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