Excoriation: A punctate or linear abrasion produced by mechanical means (often scratching), usually involving only the epidermis, but commonly reaching the papillary dermis
Ulcer: An ulcer is a discontinuity of the skin exhibiting complete loss of the epidermis and often portions of the dermis. Fissure is a lesion in the skin that is usually narrow but deep. Induration is dermal thickening causing the cutaneous surface to feel thicker and firmer. Atrophy refers to a loss of skin, and can be epidermal, dermal, or subcutaneous. With epidermal atrophy, the skin appears thin, translucent, and wrinkled. Dermal or subcutaneous atrophy is represented by depression of the skin. Maceration: softening and turning white of the skin due to being consistently wet. Umbilication is formation of a depression at the top of a papule, vesicle, or pustule. Phyma: A tubercle on any external part of the body, such as in phymatous rosacea

Configuration
"Configuration" refers to how lesions are locally grouped ("organized"), which contrasts with how they are distributed (see next section). Distribution
"Distribution" refers to how lesions are localized. They may be confined to a single area (a patch) or may exist in several places. Some distributions correlate with the means by which a given area becomes affected. For example, contact dermatitis correlates with locations where allergen has elicited an allergic immune response. Varicella zoster virus is known to recur (after its initial presentation as chicken pox) as herpes zoster ("shingles").
Such measurements can be useful to avoid central nervous system toxicity in any person receiving large doses of the drug on a chronic basis, but they are especially relevant to patients with kidney failure, who may accumulate the drug due to reduced urinary excretion rates. Manufacture
The production of benzylpenicillin involves fermentation, recovery and purification of the penicillin.The fermentation process of the production of benzylpenicillin creates the product. The presence of the product in solution inhibits the reaction and reduces the product rate and yield. Thus, in order to obtain the most product and increase the rate of reaction, it is continuously extracted. This is done by mixing the mold with either glucose, sucrose, lactose, starch, or dextrin, nitrate, ammonium salt, corn steep liquor, peptone, meat or yeast extract, and small amounts of inorganic salts.The recovery of the benzylpenicillin is the most important part of the production process because it affects the later purification steps if done incorrectly. There are several types of techniques used to recover benzyl penicillin: aqueous two-phase extraction, liquid membrane extraction, microfiltration, and solvent extraction. Extraction is more commonly used in the recovery process.In the purification step, the benzylpencillin is separated from the extraction solution. This is normally done by using a separation column. Synonyms
Penicillin II (old UK nomenclature for naming penicillins)

References
External links
"Benzylpenicillin". Drug Information Portal. U.S. National Library of Medicine.