Erythema multiforme major  is a form of rash with skin loss or epidermal detachment. The term "erythema multiforme majus" is sometimes used to imply a bullous (blistering) presentation.According to some sources, there are two conditions included on a spectrum of this same disease process:

Stevens–Johnson syndrome (SJS)
Toxic epidermal necrolysis (TEN) which described by Alan Lyell and previously called Lyell syndrome[5].In this view, EM major, SJS and TEN are considered a single condition, distinguished by degree of epidermal detachment.However, a consensus classification separates erythema multiforme minor, erythema multiforme major, and SJS/TEN as three separate entities. References

5. Orphanet Journal of Rare Diseases 2010, 5:39 doi:10.1186/1750-1172-5-39


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Clevidipine also contains glycerin (22.5 mg/mL), purified egg yolk phospholipids (12 mg/mL), and sodium hydroxide to adjust pH. Clevidipine has a pH of 6.0–8.0
In the perioperative patient population Clevidipine produces a 4–5% reduction in systolic blood pressure within 2–4 minutes after starting a 1–2 mg/hour IV infusion. In studies up to 72 hours of continuous infusion, there was no evidence of tolerance. In most patients, full recovery of blood pressure is achieved in 5–15 minutes after the infusion is stopped. Stereochemistry
Clevidipine contains a stereocenter and consists of two enantiomers. This is a racemate, ie a 1: 1 mixture of ( R ) – and the ( S ) - form:

Dosage and administration
Aseptic technique should be used when handling Cleviprex since it contains phospholipids and can support microbial growth. Cleviprex is administered intravenously and should be titrated to achieve the desired blood pressure reduction. Blood pressure and heart rate should be monitored continually during infusion. Cleviprex is a single use product that should not be diluted and should not be administered in the same line as other medications. Once the stopper is punctured, Cleviprex should be used within 12 hours and any unused portion remaining in the vial should be discarded. Change IV lines in accordance with hospital protocol. An IV infusion at 1–2 mg/hour is recommended for initiation and should be titrated by doubling the dose every 90 seconds. As the blood pressure approaches goal, the infusion rate should be increased in smaller increments and titrated less frequently.