Adverse effects for inhalational formulations of acetylcysteine include nausea, vomiting, stomatitis, fever, rhinorrhea, drowsiness, clamminess, chest tightness, and bronchoconstriction. Although infrequent, bronchospasm has been reported to occur unpredictably in some patients.Adverse effects for oral formulations of acetylcysteine have been reported to include nausea, vomiting, rash, and fever.Large doses in a mouse model showed that acetylcysteine could potentially cause damage to the heart and lungs. They found that acetylcysteine was metabolized to S-nitroso-N-acetylcysteine (SNOAC), which increased blood pressure in the lungs and right ventricle of the heart (pulmonary artery hypertension) in mice treated with acetylcysteine. The effect was similar to that observed following a 3-week exposure to an oxygen-deprived environment (chronic hypoxia). The authors also found that SNOAC induced a hypoxia-like response in the expression of several important genes both in vitro and in vivo. The implications of these findings for long-term treatment with acetylcysteine have not yet been investigated. The dose used by Palmer and colleagues was dramatically higher than that used in humans, the equivalent of about 20 grams per day. Nonetheless, positive effects on age-diminished control of respiration (the hypoxic ventilatory response) have been observed previously in human subjects at more moderate doses.Although N-acetylcysteine prevented liver damage in mice when taken before alcohol, when taken four hours after alcohol it made liver damage worse in a dose-dependent fashion. Pharmacology
Pharmacodynamics
Acetylcysteine serves as a prodrug to L-cysteine, a precursor to the biologic antioxidant glutathione. Hence administration of acetylcysteine replenishes glutathione stores.
Importance of father or father-figure
Involved fathers offer developmentally specific provisions to their children and are impacted themselves by doing so. Active father figures may play a role in reducing behavior and psychological problems in young adults. An increased amount of father–child involvement may help increase a childs social stability, educational achievement,: 5  and their potential to have a solid marriage as an adult. Their children may also be more curious about the world around them and develop greater problem solving skills. Children who were raised with fathers perceive themselves to be more cognitively and physically competent than their peers without a father. Mothers raising children together with a father reported less severe disputes with their child.The father-figure is not always a childs biological father and some children will have a biological father as well as a step- or nurturing father. When a child is conceived through sperm donation, the donor will be the "biological father" of the child. Fatherhood as legitimate identity can be dependent on domestic factors and behaviors. For example, a study of the relationship between fathers, their sons, and home computers found that the construction of fatherhood and masculinity required that fathers display computer expertise. Determination of parenthood
Roman law defined fatherhood as "Mater semper certa; pater est quem nuptiae demonstrant" ("The [identity of the] mother is always certain; the father is whom the marriage vows indicate"). The recent emergence of accurate scientific testing, particularly DNA testing, has resulted in the family law relating to fatherhood experiencing rapid changes.