Periodontal disease occurs when a number of anaerobic bacteria living on the tooth surface cause infections, which leads to a potentially sustained immune response. Diabetes is a type of condition in which infections are easier to get, and hyperglycemia contributes to the mechanism causing oral complications. Prevention
The American College of Endocrinology (ACE) and the American Association of Clinical Endocrinologists (AACE) have developed lifestyle intervention guidelines for preventing the onset of type 2 diabetes:

Healthy diet (a diet with limited refined carbohydrates, added sugars, trans fats, as well as limited intake of sodium and total calories)
Physical fitness (30–45 minutes of cardiovascular exercise per day, 3–5 days a week)
Weight loss by as little as 5–10 percent may have a significant impact on overall health

Management
There is evidence that prediabetes is a curable disease state. Although some drugs can delay the onset of diabetes, lifestyle modifications play a greater role in the prevention of diabetes. Intensive weight loss and lifestyle intervention, if sustained, may improve glucose tolerance substantially and prevent progression from IGT to type 2 diabetes. The Diabetes Prevention Program (DPP) study found a 16% reduction in diabetes risk for every kilogram of weight loss. Reducing weight by 7% through a low-fat diet and performing 150 minutes of exercise a week is the goal. The ADA guidelines recommend modest weight loss (5–10% body weight), moderate-intensity exercise (30 minutes daily), and smoking cessation.There are many dietary approaches that can reduce the risk of progression to diabetes.
Some of the surgeries may include duodenojejunostomy, laparoscopic duodenojejunostomy, or laparoscopic surgery.The timeline for recovery is 7 weeks. Epidemiology
No statistical information has been identified. Megaduodenum is an uncommon disease, and because of its extreme rarity of the condition only few cases has been reported in the literatures. Current Research
Since Megaduodenum is a rare disease, treatments and decisions are made based on the patients initial conditions and their responses to the provided treatments or surgeries.There are currently several ongoing clinical trials for megaduodenum. One study involves research of idiopathic megaduodenum in children which is a rare condition. The purpose of this study is to present the management of idiopathic megaduodenum in children. References
Further reading
Basilisco, G (1997). "Hereditary megaduodenum". The American Journal of Gastroenterology. 92 (1): 150–3. PMID 8995957. Law, David H.; Ten Eyck, Edward A. (1962). "Familial megaduodenum and megacystis". The American Journal of Medicine. 33 (6): 911. doi:10.1016/0002-9343(62)90222-X. Sturtevant, Mills (1939). "Megaduodenum and Duodenal Obstruction: Criteria for Diagnosis". Radiology. 33 (2): 185–8. doi:10.1148/33.2.185. Raia, Arrigo; Acquaroni, Danilo; Netto, Alipio Correa (1961). "Pathogenesis and treatment of acquired megaduodenum". The American Journal of Digestive Diseases. 6 (8): 757–71. doi:10.1007/BF02231059. PMID 13739156. S2CID 7354820. Gillespie, H. W. (1939). "Megaduodenum and Gastromegaly". British Journal of Radiology. 12 (136): 221–4. doi:10.1259/0007-1285-12-136-221. == External links ==