In medicine, myopathy is a disease of the muscle in which the muscle fibers do not function properly. This results in muscular weakness. Myopathy means muscle disease (Greek : myo- muscle + patheia -pathy : suffering). This meaning implies that the primary defect is within the muscle, as opposed to the nerves ("neuropathies" or "neurogenic" disorders) or elsewhere (e.g., the brain). Muscle cramps, stiffness, and spasm can also be associated with myopathy. Capture myopathy can occur in wild or captive animals, such as deer and kangaroos, and leads to morbidity and mortality. It usually occurs as a result of stress and physical exertion during capture and restraint. Muscular disease can be classified as neuromuscular or musculoskeletal in nature. Some conditions, such as myositis, can be considered both neuromuscular and musculoskeletal. Signs and symptoms
Common symptoms include muscle weakness, cramps, stiffness, and tetany. Systemic diseases
Myopathies in systemic disease results from several different disease processes including endocrine, inflammatory, paraneoplastic, infectious, drug- and toxin-induced, critical illness myopathy, metabolic, collagen related, and myopathies with other systemic disorders. Patients with systemic myopathies often present acutely or sub acutely. On the other hand, familial myopathies or dystrophies generally present in a chronic fashion with exceptions of metabolic myopathies where symptoms on occasion can be precipitated acutely. Most of the inflammatory myopathies can have a chance association with malignant lesion; the incidence appears to be specifically increased only in patients with dermatomyositis.There are many types of myopathy. ICD-10 codes are provided here where available.
It can often be treated by drugs like corticosteroids or immunosuppressants. Inclusion body myositis is a slowly progressive disease that produces weakness of hand grip and straightening of the knees. No effective treatment is known. (M61) Myositis ossificans
(M62.89) Rhabdomyolysis and (R82.1) myoglobinuriasThe Food and Drug Administration is recommending that physicians restrict prescribing high-dose Simvastatin (Zocor, Merck) to patients, given an increased risk of muscle damage. The FDA drug safety communication stated that physicians should limit using the 80-mg dose unless the patient has already been taking the drug for 12 months and there is no evidence of myopathy. "Simvastatin 80 mg should not be started in new patients, including patients already taking lower doses of the drug," the agency states. Statin-associated autoimmune myopathy

Myocardium / cardio-myopathy
(I40) Acute myocarditis
(I41) Myocarditis in diseases classified elsewhere
(I42) Cardiomyopathy
(I42.0) Dilated cardiomyopathy
(I42.1) Obstructive hypertrophy cardiomyopathy
(I42.2) Other hypertrophic cardiomyopathy
(I42.3) Endomyocardial (eosinophilic) disease
Eosinophilic myocarditis
Endomyocardial (tropical) fibrosis
Löfflers endocarditis
(I42.4) Endocardial fibroelastosis
(I42.5) Other restrictive cardiomyopathy
(I42.6) Alcoholic cardiomyopathy
(I42.8) Other cardiomyopathies
Arrhythmogenic right ventricular dysplasia
(I43) Cardiomyopathy in diseases classified elsewhere

Differential diagnosis
At birth

None as systemic causes; mainly hereditaryOnset in childhood

Inflammatory myopathies – dermatomyositis, polymyositis (rarely)
Infectious myopathies
Endocrine and metabolic disorders – hypokalemia, hypocalcemia, hypercalcemiaOnset in adulthood
Inflammatory myopathies – polymyositis, dermatomyositis, inclusion body myositis, viral (HIV)
Infectious myopathies
Endocrine myopathies – thyroid, parathyroid, adrenal, pituitary disorders
Toxic myopathies – alcohol, corticosteroids, narcotics, colchicines, chloroquine
Critical illness myopathy
Metabolic myopathies
Paraneoplastic myopathy

Treatments
Because different types of myopathies are caused by many different pathways, there is no single treatment for myopathy. Treatments range from treatment of the symptoms to very specific cause-targeting treatments.