North America and Western Europe
The most common malignant tumors in the liver represent metastases (spread) from tumors which originate elsewhere in the body. Among cancers that originate from liver tissue, HCC is the most common primary liver cancer. In the United States, the US surveillance, epidemiology, and end results  database program, shows that HCC accounts for 65% of all cases of liver cancers. As screening programs are in place for high-risk persons with chronic liver disease, HCC is often discovered much earlier in Western countries than in developing regions such as sub-Saharan Africa.Acute and chronic hepatic porphyrias (acute intermittent porphyria, porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria) and tyrosinemia type I are risk factors for hepatocellular carcinoma. The diagnosis of an acute hepatic porphyria (AIP, HCP, VP) should be sought in patients with HCC without typical risk factors of hepatitis B or C, alcoholic liver cirrhosis, or hemochromatosis. Both active and latent genetic carriers of acute hepatic porphyrias
are at risk for this cancer, although latent genetic carriers have developed the cancer at a later age than those with classic symptoms. Patients with acute hepatic porphyrias should be monitored for HCC.The incidence of HCC is relatively lower in the Western Hemisphere than in Eastern Asia. However, despite the statistics being low, the diagnosis of HCC has increased since the 1980s and it is continuing to increase, making it one of the rising causes of death due to cancer. The common risk factor for HCC is hepatitis C, along with other health issues.
Sterile or sterility may refer to:

Asepsis, a state of being free from biological contaminants
Sterile (archaeology), a sediment deposit which contains no evidence of human activity
Sterilization (microbiology), any process that eliminates or kills all forms of life or removes them from an item or a field
Sterility (physiology), an inability of a living organism to effect sexual reproduction
Infertility, a medical condition which prevents a person, an animal or a plant from bearing children, especially through natural means
Sterile Records, a record label which was formed by Nigel Ayers and Caroline K of the post-industrial music group Nocturnal Emissions in London in 1979

See also
Sterilization (disambiguation)