Another monoclonal antibody treatment, lebrikizumab, is in phase 3 trials in the US; the drug has been granted Fast Track Designation by the FDA, and Eli Lilly and Company is expected to apply for FDA approval of the drug in the second half of 2022.Some JAK inhibitors such as abrocitinib, trade name Cibinquo, and upadacitinib, trade name Rinvoq, have been approved in the US for the treatment of moderate-to-severe eczema as of January 2022. Tentative, low-quality evidence indicates that allergy immunotherapy is effective in AD. This treatment consists of a series of injections or drops under the tongue of a solution containing the allergen.Antibiotics, either by mouth or applied topically, are commonly used to target overgrowth of S. aureus in the skin of people with AD, but a 2019 meta-analysis found no clear evidence of benefit. Light
A more novel form of treatment involves exposure to broad- or narrow-band ultraviolet (UV) light. UV radiation exposure has been found to have a localized immunomodulatory effect on affected tissues and may be used to decrease the severity and frequency of flares. In particular, the usage of UVA1 is more effective in treating acute flares, whereas narrow-band UVB is more effective in long-term management scenarios. However, UV radiation has also been implicated in various types of skin cancer, and thus UV treatment is not without risk. UV phototherapy is not indicated in young adults and children due to this risk of skin cancer with prolonged use or exposure.
Out may refer to:

Arts, entertainment, and media
Films
Out (1957 film), a documentary short about the Hungarian Revolution of 1956
Out (1982 film), an American film directed by Eli Hollander
Out (2002 film), a Japanese film based on the novel by Natsuo Kirino and directed by Hideyuki Hirayama
Out (2013 film), a Canadian short comedy film directed by Jeremy LaLonde
Out (2017 film), a Slovak film directed by György Kristóf
Out (2020 film), an American animated film produced by Pixar

Music
Out (jazz) or outside, an approach to jazz improvisation
OUT, a band produced by Adam Walton
OUT, a 1994 album by Nav Katze
Out (In Essence), a 1991 album by Fluke

Television
Out (miniseries), a 1978 British television crime drama starring Tom Bell
"Out" (Dark Angel), a television episode

Other uses in arts, entertainment, and media
Out (magazine), an LGBT fashion, entertainment, and lifestyle magazine
Out (novel), a 1997 novel by Natsuo Kirino
OUTeverywhere, a community website for LGBT people around the world

Sports and recreation
Out (baseball), a play which retires the batter or a base runner
Out (cricket), the loss of a wicket by a batsman; also known as "dismissal"
Out (poker), an unseen card which is expected to win a hand, if drawn
Out (route), a pattern run by a receiver in American football

Sexuality
Coming out, publicly revealing ones own LGBT status
Outing, publicly revealing someone elses LGBT status

Mathematics
Out(Fn), the outer automorphism group of a free group on n generators
Outer automorphism group, a quotient Out(G) of the automorphism group

Transport
Outwood railway station, West Yorkshire, National Rail station code

Other uses
Out, a procedure word in voice radio communication

See also
Outing (disambiguation)
Outside (disambiguation)
All pages with titles containing Out
All pages with titles beginning with Out