Central centrifugal cicatricial alopecia (CCCA), is a type of alopecia first noticed in African Americans in the 1950s and reported by LoPresti et al. in  1968 as a result of application of petrolatum followed by a stove-heated iron comb. The original theory was that the hot petrolatum would travel down to the hair root, burn the follicle, and after repetitive injury scarring would result. Later CCCA was realized to affect men and women without a history significant for use of such styling techniques. Consequently, the terms "follicular degeneration syndrome" per Sperling and Sau in 1992 and then CCCA per Olsent et al. in 2003 were evolved. Plausible contributing factors may include other African-American styling techniques such as relaxers, tight braids, heavy extensions, certain oils, gels or pomades. Presentation
CCCA usually begins at the central (sagittal) midline of the scalp. It is symmetric and exhibits scarring as the name suggests. It involves solely the top of the scalp or may progress to Hamilton–Norwood scale Type VI or VII. Early symptoms may include pruritus, dysesthesias and tenderness. On examination the skin is thin with few follicular ostia and later in the disease the scalp may appear shiny. Cause
The mechanism of pathology of CCCA remains unknown; thus, the cause has only been postulated and not proven. CCCA is suspected to have a multi-factored cause. However, one theory involves pressure exerted on the internal root sheath leading to damage, which leads to the recruitment of inflammatory cells and the result of scarring.
Shes not the brightest of the family, but shes bubbly and kind. Patton Chase (Ryan Pinkston) – The youngest of the children, and the shortest at 410". This is a source of amusement to the family and shame to the father, and the mother is often overly-nurturing. He takes growth hormones. He is girl-crazy and his typical line to girls (and, in one episode, a guy when he was pretending to be gay to avoid being pulverized) is, "Yes I am, you likey?." It usually works, but his sisters often find it disgusting. Episodes
See also
Arrested Development – in which Richter himself played a set of identical quintuplets. References
External links
Quintuplets at IMDb