A brief trial of corticosteroids can be diagnostic for allergic causes, as the eosinophilia should resolve with suppression of the immune over-response. Neoplastic disorders are diagnosed through the usual methods, such as bone marrow aspiration and biopsy for the leukemias, MRI/CT to look for solid tumors, and tests for serum LDH and other tumor markers. Treatment
Treatment is directed toward the underlying cause. However, in primary eosinophilia, or if the eosinophil count must be lowered, corticosteroids such as prednisone may be used. However, immune suppression, the mechanism of action of corticosteroids, can be fatal in patients with parasitosis. List of causes
Eosinophilia can be idiopathic (primary) or, more commonly, secondary to another disease. In the Western World, allergic or atopic diseases are the most common causes, especially those of the respiratory or integumentary systems. In the developing world, parasites are the most common cause. A parasitic infection of nearly any bodily tissue can cause eosinophilia. Diseases that feature eosinophilia as a sign include:

Allergic disorders
Asthma
Hay fever
Drug allergies
Allergic skin diseasesPemphigus
Dermatitis herpetiformis
IgG4-related disease
Parasitic infections
Addisons disease and stress-induced suppression of adrenal gland function
Some forms of malignancy
Acute lymphoblastic leukemia
Chronic myelogenous leukemia
Eosinophilic leukemia
Clonal eosinophilia
Hodgkin lymphoma
Some forms of non-Hodgkin lymphoma
Lymphocyte-variant hypereosinophilia
Systemic mastocytosis
Systemic autoimmune diseasesSystemic lupus erythematosus
Kimura disease
Eosinophilic granulomatosis with polyangiitis
Eosinophilic fasciitis
Eosinophilic myositis
Eosinophilic myocarditis
Eosinophilic esophagitis
Eosinophilic gastroenteritis
Cholesterol embolism (transiently)
Coccidioidomycosis (Valley fever), a fungal disease prominent in the US Southwest. Human immunodeficiency virus infection
Interstitial nephropathy
Hyperimmunoglobulin E syndrome, an immune disorder characterized by high levels of serum IgE
Idiopathic hypereosinophilic syndrome.
Dissecting cellulitis of the scalp, also known as dissecting folliculitis, perifolliculitis capitis abscedens et suffodiens of Hoffman, perifolliculitis abscedens et suffodiens, or folliculitis abscedens et suffodiens, is an inflammatory condition of the scalp that can lead to scarring alopecia, which begins with deep inflammatory nodules, primarily over occiput, that progresses to coalescing regions of boggy scalp. Boggy tissue has a high fluid level that results in a spongy feeling. Isotretinoin  proves to be the medicine of choice for the treatment of the disease. : 649 : 761

See also
List of cutaneous conditions

References


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