This can result in paradoxical stimulation of prostate cancer growth with bicalutamide and is responsible for the phenomenon of the antiandrogen withdrawal syndrome, where antiandrogen discontinuation paradoxically slows the rate of prostate cancer growth.In transgender women, breast development is a desired effect of antiandrogen or estrogen treatment. Breast development and gynecomastia induced by bicalutamide is thought to be mediated by increased activation of the ER secondary to blockade of the AR (resulting in disinhibition of the ER in breast tissue) and increased levels of estradiol. In addition to fat deposition, connective tissue growth, and ductal development, bicalutamide has been found to produce moderate lobuloalveolar development of the breasts. However, full lobuloalveolar maturation necessary for lactation and breastfeeding will not occur without progestogen treatment.Bicalutamide monotherapy seems to have minimal effect on testicular spermatogenesis, testicular ultrastructure, and certain aspects of male fertility. This seems to be because testosterone levels in the testes (where ≈95% of testosterone in males is produced) are extremely high (up to 200-fold higher than circulating levels) and only a small fraction (less than 10%) of the normal levels of testosterone in the testes are actually necessary to maintain spermatogenesis. As a result, bicalutamide appears to not be able to compete with testosterone in this sole part of the body to an extent sufficient to considerably interfere with androgen signaling and function.
Martian dust storms are formed when solar heating warms the Martian atmosphere and causes the air to move, lifting dust off the ground. The chance for storms is increased when there are great temperature variations like those seen at the equator during the Martian summer. See also
Coccidioidomycosis
Dry line
Dust storm warning
Haboob
Iberulites
List of dust storms
Mineral dust
Saharan Air Layer
Shamal (wind)
Sirocco

References
External links

12-hour U.S. map of surface dust concentrations Mouse-over an hour block on the row for Surface Dust Concentrations
Dust in the Wind Archived 2020-04-16 at the Wayback Machine
Photos of the April 14 1935 and September 2 1934 dust storms in the Texas Panhandle hosted by the Portal to Texas History. University of Arizona Dust Model Page
Photos of a sandstorm in Riyadh in 2009 from the BBC Newsbeat website
Dust storm in Phoenix Arizona via YouTube