Fosdenopterin (or cyclic pyranopterin monophosphate, cPMP), sold under the brand name Nulibry, is a medication used to reduce the risk of death due to a rare genetic disease known as molybdenum cofactor deficiency type A.The most common side effects include complications related to the intravenous line, fever, respiratory infections, vomiting, gastroenteritis, and diarrhea.Fosdenopterin was approved for medical use in the United States in February 2021,  It is the first medication approved by the U.S. Food and Drug Administration (FDA) for the treatment of molybdenum cofactor deficiency type A. and in the European Union in September 2022. Medical uses
Fosdenopterin is indicated to reduce the risk of mortality in people with molybdenum cofactor deficiency  (MoCD) type A. Mechanism of action
People with molybdenum cofactor deficiency type A cannot produce cyclic pyranopterin monophosphate (cPMP) in their body. Fosdenopterin is an intravenous medication that replaces the missing cPMP. cPMP is a precursor to molybdopterin, which is required for the enzyme activity of sulfite oxidase, xanthine dehydrogenase/oxidase and aldehyde oxidase. History
Fosdenopterin was developed at the German universities TU Braunschweig and the University of Cologne.The effectiveness of fosdenopterin for the treatment of MoCD-A was demonstrated in thirteen treated participants compared to eighteen matched, untreated participants. The participants treated with fosdenopterin had a survival rate of 84% at three years, compared to 55% for the untreated participants.The U.S. Food and Drug Administration (FDA) granted the application for fosdenopterin priority review, breakthrough therapy, and orphan drug designations along with a rare pediatric disease priority review voucher.
Heather may refer to:

Plants
The heather family, or Ericaceae, particularly:
Common heather or ling, Calluna
Various species of the genus Cassiope
Various species of the genus Erica

Name
Heather (given name)
Heather (surname)

Arts and media
Heathers, a 1989 film directed by Michael Lehmann
Heathers: The Musical, a musical by Laurence OKeefe based on the film
Heathers (TV series), a 2018 television series based on the film
"Heather" (The Secret Circle), a television episode

Music
Heathers (band), an acoustic singing duo from Ireland
"Heather" (Beatles song), an unreleased 1968 song by Paul McCartney and Donovan
"Heather" (Conan Gray song), a 2020 song by American singer Conan Gray
"Heather", a song from fusion drummer Billy Cobhams 1974 album Crosswinds
"Heather", a 2001 song by Paul McCartney from the album Driving Rain
"Heather", a song from Patent Pending by Heavens
"Heather", a version of the Johnny Pearson song, "Autumn Reverie", which appeared on the Carpenters album Now & Then
”Heather”, a song from I Know Leopard’s album Love is a Landmine

Places
Heather, Leicestershire, a village in England
Heather Preceptory, a preceptory of the Knights Hospitaller, established in the above village
Heather St Johns Football Club, an English football club based in the above village
Heather, Missouri, a community in the United States
Heather, Washington, an unincorporated community in the United States

Other uses
Heather (fabric), interwoven yarns of mixed colours producing muted greyish shades with flecks of colour
Heather (yacht), the original name of the yacht USS Sea Gull, built in 1902
Heather, brand name of a progestogen-only pill containing norethisterone (norethindrone)

See also
Heath (disambiguation)
Heather Hills (disambiguation)
Hurricane Heather