Susceptible bacteria
According to the product package insert, ofloxacin is effective against these microorganisms:Aerobic Gram-positive microorganisms:

Staphylococcus aureus (methicillin-susceptible strains)
Streptococcus pneumoniae (penicillin-susceptible strains)
Streptococcus pyogenesAerobic Gram-negative microorganisms 

Citrobacter koseri (Citrobacter diversus)
Enterobacter aerogenes
Escherichia coli
Haemophilus influenzae
Klebsiella pneumoniae
Neisseria gonorrhoeae
Proteus mirabilis
Pseudomonas aeruginosaOther microorganisms:

Chlamydia trachomatis

Adverse effects
In general, fluoroquinolones are well tolerated, with most side effects being mild to moderate. On occasion, serious adverse effects occur. Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes. A U.S. Centers for Disease Control study found patients treated with fluoroquinolones experienced adverse events severe enough to lead to an emergency department visit more frequently than those treated with cephalosporins or macrolides, but less frequently than those treated with penicillins, clindamycin, sulfonamides, or vancomycin.Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class. Among these, tendon problems and exacerbation of the symptoms of the neurological disorder myasthenia gravis are the subject of "black box" warnings in the United States. The most severe form of tendonopathy associated with fluoroquinolone administration is tendon rupture, which in the great majority of cases involves the Achilles tendon. Younger people typically experience good recovery, but permanent disability is possible, and is more likely in older patients. The overall frequency of fluoroquinolone-associated Achilles tendon rupture in patients treated with ciprofloxacin or levofloxacin has been estimated at 17 per 100,000 treatments.
Bleb or bulla
The most common disease causing blebs or bullae is paraseptal emphysema though centrilobular emphysema may sometimes be involved. Other conditions associated with lung bullae are:
Other conditions associated with lung bullae are:

Alpha 1-antitrypsin deficiency
Marfan syndrome
Ehlers–Danlos syndromes
Cocaine smoking
Sarcoidosis
HIV/AIDS
Intravenous substance abuse

Cyst
A pulmonary cyst is not necessarily the same type of cyst seen in many cystic lung diseases. The cyst for example in pneumocystis pneumonia is not the same as the pulmonary cyst. Cystic lung diseases include:

Langerhans cell histiocytosis (LCH)
Lymphangioleiomyomatosis (LAM)
Lymphocytic interstitial pneumonia (LIP)
Birt–Hogg–Dubé syndrome
Pneumocystis pneumonia
Pulmonary amyloidosis
Light chain deposition disease
Lung metastases rarely cause multiple cystic lung lesions. This form of presentation has been described in metastatic sarcomas. Incidental blebs and cysts
A focal lung pneumatosis that is an incidental imaging finding such as on a CT scan, without suspicious findings (such as findings indicating any of the diseases listed above), generally does not indicate further follow-up. Cavity

Two infectious diseases that are commonly associated with cavities of lung tissue are Mycobacterium tuberculosis and Klebsiella pneumoniae. The formation of cavities is due to tissue necrosis and creates an environment that allows the pathogen to expand in numbers and spread further.In the absence of infectious symptoms, a lung nodule with cavitation is a suspected lung cancer. == References ==