Reperfusion protection in obligate hibernators
Obligatory hibernators such as the ground squirrels show resistance to ischemia/reperfusion (I/R) injury in liver, heart, and small intestine during the hibernation season when there is a switch from carbohydrate metabolism to lipid metabolism for cellular energy supply. This metabolic switch limits anaerobic metabolism and the formation of lactate, a herald of poor prognosis and multi-organ failure (MOF) after I/R injury. In addition, the increase in lipid metabolism generates ketone bodies and activates peroxisome proliferating-activated receptors (PPARs), both of which have been shown to be protective against I/R injury. See also
Crush syndrome
Ischemic stroke
Myocardial infarction — Reperfusion
Therapeutic hypothermia
Hypothermia therapy for neonatal encephalopathy
Remote ischemic conditioning
Ischemia-reperfusion injury of the appendicular musculoskeletal system

References


== External links ==
Laryngotracheitis may refer to:

the combination of the following two medical conditions: laryngitis and tracheitis
a disease of poultry caused by Gallid alphaherpesvirus 1