Two to three doses of SP has been proven to reduce the levels of placental malaria  and had a reduced risk of moderate to severe anemia. Prevention
Ways to minimise exposure to the Anopheles mosquito include:

Indoor residual sprays are one of the most utilised methods of malaria prevention by the Global Malaria Eradication Campaign. Spraying is a method used to control malaria epidemics. Nets treated with insecticide are effective at preventing mosquito contact for three years. The World Health Organization (WHO) specifically protects younger children and pregnant women in order to reduce the risk of spreading quartan fever within the population. Sulfadoxine-pyrimethamine (SP) administration to pregnant women is also a source of prevention in order to reduce the risks of maternal anaemia, low birth rate, and perinatal mortality. SP reduces the impact quartan fever may have on newborns and decrease the mortality rate. This method of prevention is known as "chemoprevention." House improvement is also a method of prevention. Traditional houses consisting of natural materials are susceptible to gaps which allow entry to Anopheles mosquitoes. House improvements including sealed windows and doors reduce the risk of coming in contact with the infected mosquitoes. Larval source management is the control and monitoring of aquatic environments in order to prevent Anopheles mosquitoes from fully developing. Mosquitoes require aquatic environments in order to fully mature and develop. Once the mosquito eggs hatch, the larva must live in the water and develop into pupa. The pupa stage then matures into a fully developed mosquito and emerges from its aquatic habitat.
Uninucleated merozoites can also mature into uninucleate gametocytes which can invade and infect other female Anopheles mosquitoes during feeding, thus spreading the disease onto a wider population of humans. Diagnosis
Fevers in intervals of 72 hours distinguish quartan fever from other forms of malaria where fevers range in 48 hour intervals or fever spikes that occur sporadically.Early indications of quartan fever include having irritated spots, welts, hives and burning skin, however this is dependent on individuals tolerance to mosquito bites and may not be evident on some people. With the Anopheles malaria mosquitoes, the welts are most likely to not appear unless there are severe allergic reactions.The prepatent period is the time interval for when parasites infect a host and when they can be detected on a thick blood film. For quartan fever, P. malariae has a prepatent period ranging from 16 to 59 days. Specifically in the case of quartan fever, the rupturing of liver stage schizonts releases merozoites. This stage of the P. malariae life cycle is known as the "ring stages" and are the first stages which can be detected in human blood for diagnosis. Medical procedures that diagnose a patient with quartan fever
Blood smears can be used to detect the parasites within red blood cells, thick blood smears are typically used initially to detect the parasites, then it is followed by thin blood smears which can detect the parasites as the morphology of erythrocytes is maintained through the process.