- Hyperthermia — elevated body temperature
- Autonomic instability (e.g. tachycardia, high blood pressure, diaphoresis, diarrhoea, etc. )Urinary retention — the inability to pass urine despite having urine to pass. Blood dyscrasias e.g. agranulocytosis (a potentially fatal drop in white blood cell count), leukopaenia (a drop in white blood cell counts but not to as extreme an extent as agranulocytosis), neutropaenia (a drop in neutrophil [the cells of the immune system that specifically destroy bacteria] count), thrombocytopaenia (a dangerous drop in platelet [a cell found in the blood that plays a crucial role in the blood clotting process] counts), purpura (the appearance of red or purple discolourations of the skin that do not blanch when pressure is applied), eosinophilia (raised eosinophil [the cells of the immune system that specifically fights off parasites] count)
Hepatitis — inflammation of the liver
Jaundice
Pigmentary retinopathy
Anaphylactoid reactions
Oedema — the abnormal buildup of fluids in the tissues
Asthma
Coma
Seizures
Confusional states
Disorientation
Incoordination
Ataxia
Tremors
Peripheral neuropathy — nerve damage
Numbness, tingling and paresthesias of the extremities
Dysarthria
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Tinnitus — falsely hearing ringing in the ears. Alteration in EEG patterns
Paralytic ileus — cessation of the peristaltic waves that propel partially digested food through the digestive tract. Hyperpyrexia (elevated body temperature)
Disturbance of accommodation
Increased intraocular pressure
Mydriasis

Pharmacology
Binding affinities (Ki[nM]; for human cloned receptors when available)

See also
Flupentixol/melitracen
Olanzapine/fluoxetine
Tranylcypromine/trifluoperazine


== References ==
Thus, any medication that is metabolized by the CYP3A4 enzyme will potentially have elevated levels when oral clotrimazole is used. The prescribing physician should be aware of any medication the patient is taking prior to starting oral clotrimazole. Certain medications should not be taken with oral clotrimazole. Pharmacology
Pharmacodynamics
Clotrimazole is an imidazole derivative which works by inhibiting the growth of individual Candida or fungal cells by altering the permeability of the fungal cell wall. It binds to phospholipids in the cell membrane and inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production. Clotrimazole may slow fungal growth or result in fungal cell death. Sales volume
Clotrimazole is available as a generic medication, and in 2016 Canesten brand Clotrimazole was one of the biggest-selling branded over-the-counter medications sold in Great Britain, with sales of £39.2 million. References
External links
"Clotrimazole". Drug Information Portal. U.S. National Library of Medicine.