It may be further divided as nonamnestic single- or multiple-domain MCI, and these individuals are believed to be more likely to convert to other dementias (for example, dementia with Lewy bodies).The International Classification of Diseases classifies MCI as a "mental and behavioural disorder." Causes
Mild cognitive impairment (MCI) may be caused due to alteration in the brain triggered during early stages of Alzheimers disease or other forms of dementia. Exact causes of MCI are unknown. It is controversial whether MCI even should be identified as a disorder.Risk factors of both dementia and MCI are considered to be the same: these are aging, genetic (heredity) cause of Alzheimers or other dementia, and cardiovascular disease.Individuals with MCI have increased oxidative damage in their nuclear and mitochondrial brain DNA. Diagnosis
The diagnosis of MCI requires considerable clinical judgement, and as such a comprehensive clinical assessment including clinical observation, neuroimaging, blood tests and neuropsychological testing are best in order to rule out an alternate diagnosis. MCI is diagnosed when there is:
Evidence of memory impairment
Preservation of general cognitive and functional abilities
Absence of diagnosed dementia

Neuropathology
Although amnestic MCI patients may not meet criteria for Alzheimers disease, patients may be in a transitional stage of evolving Alzheimers disease.Magnetic resonance imaging can observe deterioration, including progressive loss of gray matter in the brain, from mild cognitive impairment to full-blown Alzheimer disease. A technique known as PiB PET imaging is used to show the sites and shapes of beta amyloid deposits in living subjects using a 11C tracer that binds selectively to such deposits.
Vasopressin also plays a role in autism, major depressive disorder, bipolar disorder, and schizophrenia. See also
Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH)
Oxytocin
Vasopressin receptor
Vasopressin receptor antagonists
Copeptin
Anterior Pituitary
Hypothalamus

References


== Further reading ==