History
Marfan syndrome is named after Antoine Marfan, the French pediatrician who first described the condition in 1896 after noticing striking features in a five-year-old girl. The gene linked to the disease was first identified by Francesco Ramirez at the Mount Sinai Medical Center in New York City in 1991. Famous patients
Famous people who have had Marfan syndrome include:

Isaiah Austin
Javier Botet
Austin Carlile
Bradford Cox
Euell Gibbons
Flo Hyman
Jonathan Jeanne
Vincent Schiavelli
Troye Sivan
John TavenerIn addition the following historical figures and celebrities often appear on lists of people with Marfan syndrome, but from case to case the evidence is speculative, questionable, or even refuted. See also
Ehlers–Danlos syndrome
Kashin–Beck disease
Loeys–Dietz syndrome
Nail-Patella syndrome
Mitral valve prolapse

Bibliography
Lorenz, Megaera. "Lorenz, Maegara "The Mystery of Akhenaton: Genetics or Aesthetics"". Heptune.com. Archived from the original on February 8, 2010. Retrieved March 21, 2010. Montserrat, Dominic (2003) [2000]. Akhenaten: History, Fantasy and Ancient Egypt (1st paperback ed.). London; New York: Routledge. ISBN 0415301866. Reeves, Nicholas (2019) [2001]. Akhenaten: Egypts False Prophet (Electronic ed.). London; New York: Thames & Hudson. ISBN 978-0-500-29469-7. LCCN 00108868. References
External links

Marfan syndrome at Curlie
Orphanets disease page on Marfan syndrome
This is consistent with the observation that animal screening models indicate putative antidepressant activity for this compound, although one study has been negative. Formal clinical trials in depressed patients have not been reported.It has also been investigated for use in the treatment of cancer. Captopril stereoisomers were also reported to inhibit some metallo-β-lactamases. Adverse effects
Adverse effects of captopril include cough due to increase in the plasma levels of bradykinin, angioedema, agranulocytosis, proteinuria, hyperkalemia, taste alteration, teratogenicity, postural hypotension, acute renal failure, and leukopenia. Except for postural hypotension, which occurs due to the short and fast mode of action of captopril, most of the side effects mentioned are common for all ACE inhibitors. Among these, cough is the most common adverse effect. Hyperkalemia can occur, especially if used with other drugs which elevate potassium level in blood, such as potassium-sparing diuretics. Other side effects are:

Itching
Headache
Tachycardia
Chest pain
Palpitations
Dysgeusia
WeaknessThe adverse drug reaction (ADR) profile of captopril is similar to other ACE inhibitors, with cough being the most common ADR. However, captopril is also commonly associated with rash and taste disturbances (metallic or loss of taste), which are attributed to the unique thiol moiety. Overdose
ACE inhibitor overdose can be treated with naloxone. History
In the late 1960s, John Vane of the Royal College of Surgeons of England was working on mechanisms by which the body regulates blood pressure. He was joined by Sérgio Henrique Ferreira of Brazil, who had been studying the venom of a Brazilian pit viper, the jararaca (Bothrops jararaca), and brought a sample of the vipers venom.