The literature started with the argument that female orgasm is a byproduct of shared early male ontogeny, where male orgasm is an adaptation. Research has shifted to investigate and also support the sire-choice hypothesis, which proposes that female orgasm has been shaped by natural selection to function in the selection of high quality sires (male parents) for offspring. Therefore, orgasm increases the chances of conceiving with males of a high genetic quality. Research by Randy Thornhill et al. (1995) suggested that female orgasm is more frequent during intercourse with a male partner with low fluctuating asymmetry. Selective pressure and mating
Wallen K and Lloyd EA stated, "In men, orgasms are under strong selective pressure as orgasms are coupled with ejaculation and thus contribute to male reproductive success. By contrast, womens orgasms in intercourse are highly variable and are under little selective pressure as they are not a reproductive necessity. "Desmond Morris suggested in his 1967 popular-science book The Naked Ape that the female orgasm evolved to encourage physical intimacy with a male partner and help reinforce the pair bond. Morris suggested that the relative difficulty in achieving female orgasm, in comparison to the males, might be favorable in Darwinian evolution by leading the female to select mates who bear qualities like patience, care, imagination, and intelligence, as opposed to qualities like size and aggression, which pertain to mate selection in other primates. Such advantageous qualities thereby become accentuated within the species, driven by the differences between male and female orgasm.
Screening for critical congenital heart defect should be done on all newborns after 24hours or shortly before discharge. Oxygen saturation is measured in the right hand and either foot.A screening is considered positive if:

Oxygen saturation <90% in either extremity,
Oxygen saturation 90-94% in both extremities on 3 measurements separated by an hour each,
Oxygen saturation difference >3% between both extremities on 3 measurements separated by an hour each. Management
Treatment for blue baby syndrome will depend on the underlying cause. When evaluating a patient for cyanosis or respiratory distress, vital signs should be monitored, especially the patients heart rate and oxygen saturation. It is beneficial to have vascular access established. In newborns, the pulse oximeter is typically placed on the right hand to determine pre-ductal oxygenation, referring to oxygenation before the ductus arteriosus (connection between aorta and pulmonary artery). This gives the oxygenation level the heart and brain receive. Traditionally, supplemental oxygen is given in an escalating manner beginning with free-flowing oxygen, progressing to positive pressure ventilation or continuous positive airway pressure, and ending with mechanical intubation. The goal oxygen saturation is between 85 and 95%. If an infant requires supplemental oxygen for a prolonged time it should be heated and humidified to avoid heat loss. Cyanotic heart disease
Some babies born with cyanotic heart disease are treated with prostaglandin E1 after birth to keep the ductus arteriosus open and allow for more oxygenated blood to be pumped to the body. Many also receive oxygen therapy to increase the percentage of oxygen in the blood.