There are a variety of prescription opioid-based cough relievers, such as hydrocodone and codeine, but have unwanted side effects and potential of abuse and diversion. However, benzonatate is currently the only prescription non-opioid antitussive and its usage has been rapidly increasing. The exact reasons of this increase are unclear. Economics
In the United States between 2004 and 2009, prescriptions increased 50% from 3.1 million to 4.7 million, the market share of benzonatate among antitussives increased from 6.3% to 13%, and the estimated number of children under the age of 10 years receiving benzonatate increased from 10,000 to 19,000. Throughout this same period, greater than 90% of prescriptions were given to those 18 or older. The majority of prescriptions were given by general, family, internal, and osteopathic physicians with pediatricians account for about 3% of prescribed benzonatate.In 2019, it was the 105th most commonly prescribed medication in the United States, with more than 6 million prescriptions. Brand names
Tessalon is a brand name version of benzonatate manufactured by Pfizer, Inc. It is available as perles or capsules. Zonatuss was a brand name manufactured by Atley Pharmaceuticals, Inc. and Vertical Pharmaceuticals, Inc.

References
External links
"Benzonatate". Drug Information Portal. U.S. National Library of Medicine.
Phakomatosis pigmentokeratotica is a rare neurocutanous condition  characterized by the combination of an organoid sebaceous nevus and speckled lentiginous nevus. : 634–5 : 776  It is an unusual variant of  epidermal naevus syndrome. It was first described by Happle et al. It is often associated with neurological or skeletal anomalies such as hemiatrophy, dysaesthesia and hyperhidrosis in a segmental pattern, mild mental retardation, seizures, deafness, ptosis and strabismus. See also
Skin lesion
List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer

References


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