Lisa Lee Dark
Betsy Driver
Casimir Pulaski, hypothesized based on examination of remains

See also
Disorders of sex development
Inborn errors of steroid metabolism
Intersex
List of vaginal anomalies
5α-Reductase 2 deficiency
Androgen insensitivity syndrome

References
Further reading
Han, Thang S.; Walker, Brian R.; Arlt, Wiebke; Ross, Richard J. (17 December 2013). "Treatment and health outcomes in adults with congenital adrenal hyperplasia". Nature Reviews Endocrinology. 10 (2): 115–124. doi:10.1038/nrendo.2013.239. PMID 24342885. S2CID 6090764Figure 2: The adrenal steroidogenesis pathway. {{cite journal}}:  CS1 maint: postscript (link)

External links

Congenital adrenal hyperplasia at Curlie
Congenital cases may have developmental abnormality due to abnormal muscle structure, usually muscle atrophy / hypertrophy or rarely, absence of the muscle and incorrect placement. Specific & common causes include:

Superior oblique Palsy / Congenital fourth nerve palsy
Inferior oblique overaction
Browns syndrome
Duanes retraction syndrome
Double elevator palsy
Fibrosis of rectus muscle in Graves Disease (most commonly inferior rectus is involved)
Surgical trauma to the vertical muscles (e.g. during scleral buckling surgery or cataract surgery causing iatrogenic trauma to the vertical muscles).Sudden onset hypertropia in a middle aged or elderly adult may be due to compression of the trochlear nerve and mass effect from a tumor, requiring urgent brain imaging using MRI to localise any space occupying lesion. It could also be due to infarction of blood vessels supplying the nerve, due to diabetes and atherosclerosis. In other instances it may be due to an abnormality of neuromuscular transmission, i.e., Myasthenia Gravis. Treatment
In general, strabismus can be approached and treated with a variety of procedures. Depending on the individual case, treatment options include:

Correction of refractive errors by glasses
Prism therapy (if tolerated, to manage diplopia)
Vision Therapy
Patching (mainly to manage amblyopia in children and diplopia in adults)
Botulinum toxin injection
Surgical correctionSurgical correction of the hypertropia is desired to achieve binocularity, manage diplopia and/or correct the cosmetic defect. Steps to achieve the same depend on mechanism of the hypertropia and identification of the offending muscles causing the misalignment.