The doctrine of asatkaryavada affirms that the effect does not inhere in the cause, but is a new arising. See Nyaya for some details of the theory of causation in the Nyaya school. In Brahma Samhita, Brahma describes Krishna as the prime cause of all causes.Bhagavad-gītā 18.14 identifies five causes for any action (knowing which it can be perfected): the body, the individual soul, the senses, the efforts and the supersoul. According to Monier-Williams, in the Nyāya causation theory from Sutra I.2.I,2 in the Vaisheshika philosophy, from causal non-existence is effectual non-existence; but, not effectual non-existence from causal non-existence. A cause precedes an effect. With a threads and cloth metaphors, three causes are:

Co-inherence cause: resulting from substantial contact, substantial causes, threads are substantial to cloth, corresponding to Aristotles material cause. Non-substantial cause: Methods putting threads into cloth, corresponding to Aristotles formal cause. Instrumental cause: Tools to make the cloth, corresponding to Aristotles efficient cause.Monier-Williams also proposed that Aristotles and the Nyayas causality are considered conditional aggregates necessary to mans productive work. Buddhist philosophy
Karma is the causality principle focusing on 1) causes, 2) actions, 3) effects, where it is the minds phenomena that guide the actions that the actor performs. Buddhism trains the actors actions for continued and uncontrived virtuous outcomes aimed at reducing suffering. This follows the Subject–verb–object structure.The general or universal definition of pratityasamutpada (or "dependent origination" or "dependent arising" or "interdependent co-arising") is that everything arises in dependence upon multiple causes and conditions; nothing exists as a singular, independent entity.
Cefditoren also known as cefditoren pivoxil (trade names Zostom-O, Meiact, and Spectracef) is a broad-spectrum antibiotic, taken by mouth to treat pneumonia and other infections. It is a third-generation oral cephalosporin with a broad spectrum of activity against bacterial pathogens, including both Gram-positive and Gram-negative bacteria, and it is effective against some antibiotic-resistant bacteria because it is not susceptible to hydrolysis by many common beta-lactamases. The United States Food and Drug Administration approved cefditoren pivoxil for adults and adolescents (12 years of age or older) in 2001. In 2018 Zuventus Healthcare received approval for cefditoren pivoxil dry powder for suspension (100 mg / 5mL) for the treatment of mild to moderate infection in children (2 months to 12 years of age) which are caused by susceptible strains of the designated microorganisms.Cefditoren pivoxil may also reduce lung inflammation and epithelial damage by a non-bactericidal mechanism. It was patented in 1984 and approved for medical use in 1994. Structure
Like other cephalosporins, cefditoren has a β-lactam ring at the 7 position of cephalosporin ring that is responsible for its inhibitory action on bacterial cell wall synthesis. In addition to the cephem nucleus common to all cephalosporins, cefditoren has an aminothiazole group that enhances its activity against Gram-negative organisms, a methylthiazole group that enhances its activity against Gram-positive organisms, a methoxyimino group that gives it stability against β-lactamases, and a pivoxil ester group that enhances oral bioavailability. Antimicrobial activity
The spectrum of cefditoren includes both Gram-positive and Gram-negative bacterial species.