These factors include but are not limited to age, severity of symptoms, type of adjustment disorder, and personal preference.Different ways to help with the disorder include:

Individual Psychotherapy
Family Therapy
Peer Group Therapy
Medication (used only when the symptoms are severe or with a doctors approval)In addition to professional help, parents and caregivers can help their children with their difficulty adjusting by:

offering encouragement to talk about their emotions
offering support and understanding
reassuring the child that their reactions are normal
involving the childs teachers to check on their progress in school
letting the child make simple decisions at home, such as what to eat for dinner or what show to watch on TV
having the child engage in a hobby or activity they enjoy

Criticism
Like many of the items in the DSM, adjustment disorder receives criticism from a minority of the professional community as well as those in semi-related professions outside the healthcare field. First, there has been criticism of its classification. It has been criticized for its lack of specificity of symptoms, behavioral parameters, and close links with environmental factors. Relatively little research has been done on this condition.An editorial in the British Journal of Psychiatry described adjustment disorder as being so "vague and all-encompassing… as to be useless," but it has been retained in the DSM-5 because of the belief that it serves a useful clinical purpose for clinicians seeking a temporary, mild, non-stigmatizing label, particularly for patients who need a diagnosis for insurance coverage of therapy.In the US military there has been concern about its diagnosis in active duty military personnel.
Melphalan, sold under the brand name Alkeran among others, is a chemotherapy medication used to treat multiple myeloma, ovarian cancer, melanoma, and AL amyloidosis. It is taken by mouth or by injection into a vein.Common side effects include nausea and bone marrow suppression. Other severe side effects may include anaphylaxis and the development of other cancers. Use during pregnancy may result in harm to the fetus. Melphalan belongs to the class of nitrogen mustard alkylating agents. It works by interfering with the creation of DNA and RNA.Melphalan was approved for medical use in the United States in 1964. It is on the World Health Organizations List of Essential Medicines. It is available as a generic medication. Medical uses
It is used to treat multiple myeloma, ovarian cancer, AL amyloidosis, and occasionally malignant melanoma. The agent was first investigated as a possible drug for use in melanoma, it was not found to be effective.In 2016, it was approved in the U.S. for:

use as a high-dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation in multiple myeloma (MM) patients
the palliative treatment of MM patients for whom oral therapy is not appropriateMelphalan is used to treat ocular retinoblastoma, a pediatric solid tumor. This is accomplished via transarterial catheter based slow pulsed infusion into the ophthalmic artery.