Many sets of quadruplets contain a mixture of identical and fraternal siblings, such as three identical and one fraternal, two identical and two fraternal, or two pairs of identicals. One famous set of identical quadruplets was the Genain quadruplets, all of whom developed schizophrenia. Quadruplets are sometimes referred to as "quads" in Britain. Quintuplets
Quintuplets occur naturally in 1 in 55,000,000 births. The first quintuplets known to survive infancy were the identical female Canadian Dionne Quintuplets, born in 1934. Quintuplets are sometimes referred to as "quins" in the UK and "quints" in North America. A famous set of all-girl quintuplets are the Busby quints from the TV series OutDaughtered. Sextuplets
Born in Liverpool, England, on 18 November 1983, the Walton sextuplets were the worlds first all-female surviving sextuplets, and the worlds fourth known set of surviving sextuplets. Another well-known set of sextuplets is the Gosselin sextuplets, born on May 10, 2004, in Hershey, Pennsylvania. Reality television shows Jon & Kate Plus 8 and later Kate Plus 8 have chronicled the lives of these sextuplets. Other shows of this nature include Table for 12 and Sweet Home Sextuplets. Very high-order multiple births
In 1997, the McCaughey septuplets, born in Des Moines, Iowa, became the first septuplets known to survive infancy. Multiple births of as many as eight babies have been born alive, the first surviving set on record goes to the Suleman octuplets, born in 2009 in Bellflower, California. As of 2019, all of them were alive and turned 10 years old.
That way, the risks for the mother and fetuses are decreased. The appropriate number of embryos to be transferred depends on the age of the woman, whether it is the first, second or third full IVF cycle attempt and whether there are top-quality embryos available. According to a guideline from The National Institute for Health and Care Excellence (NICE) in 2013, the number of embryos transferred in a cycle should be chosen as in following table:
Also, it is recommended to use single embryo transfer in all situations if a top-quality blastocyst is available. Management
Bed rest has not been found to change outcomes and therefore is not generally recommended outside of a research study. Selective reduction (procedure)
Selective reduction is the practice of reducing the number of fetuses in a multiple pregnancy; it is also called "multifetal reduction".The procedure generally takes two days; the first day for testing in order to select which fetuses to remove, and the second day for the procedure itself, in which potassium chloride is injected into the heart of each selected fetus under the guidance of ultrasound imaging. Risks of the procedure include bleeding requiring transfusion, rupture of the uterus, retained placenta, infection, a miscarriage, and prelabor rupture of membranes. Each of these appears to be rare.