chimeric antigen receptor T cells directed against CD19) in adult patients with DLBCL, NOS who have relapsed after or are refractory to two or more lines of systemic therapy. The Committee for Orphan Medicinal Products of the European Medicines Agency recommends tisagenlecleucel retain its orphan drug designation. The USA Food and Drug Administration (FDA) has also approved the use of this drug for relapsed or refractory DLBCL of the large B-cell lymphoma subtype in patients who have failed after two or more lines of systemic therapy. Monoclonal antibodies directed against CD19, CD22, CD30, and PD-L1 have been developed for use as immunotherapeutic agents in other hematological malignancies and are being or plan to be tested for their usefulness in DLBCL, NOS. In August 2020, the FDA approved the humanized Fc-modified cytolytic CD19 targeting monoclonal antibody tafasitamab in combination with lenalidomide as a treatment for adult patients with relapsed or refractory DLBCL. In April 2021, the FDA approved the CD19-directed antibody-drug conjugate loncastuximab tesirine as a treatment for adult patients with relapsed or refractory DLBCL after systemic therapy. Emerging therapies
Neoplastic cell expression of CD30 in DLBCL, NOS is a favorable prognostic indicator; in these cases, brentuximab vedotin may be a useful addition to chemotherapy treatment protocols. This agent is a CD30-targeting antibody that delivers a toxin, monomethyl auristatin E, to CD30-expressing cells, has therapeutic efficacy against other CD30-expressing lymphomas, and may prove useful in treating the 10–15% of DLBCL, NOS cases expressing this protein.
African histoplasmosis
Alternariosis
Antibiotic candidiasis (iatrogenic candidiasis)
Black piedra
Candidal intertrigo
Candidal onychomycosis
Candidal paronychia
Candidal vulvovaginitis
Candidid
Chromoblastomycosis (chromomycosis, cladosporiosis, Fonsecas disease, Pedrosos disease, phaeosporotrichosis, verrucous dermatitis)
Chronic mucocutaneous candidiasis
Coccidioidomycosis (California disease, desert rheumatism, San Joaquin Valley fever, valley fever)
Congenital cutaneous candidiasis
Cryptococcosis
Dermatophytid
Diaper candidiasis
Disseminated coccidioidomycosis (coccidioidal granuloma)
Distal subungual onychomycosis
Entomophthoromycosis
Erosio interdigitalis blastomycetica 
Favus
Fungal folliculitis (majocchi granuloma)
Fusariosis
Geotrichosis
Granuloma gluteale infantum
Histoplasmosis (cave disease, Darlings disease, Ohio Valley disease, reticuloendotheliosis)
Hyalohyphomycosis
Kerion
Lobomycosis (keloidal blastomycosis, lacaziosis, Lobos disease)
Mucormycosis
Mycetoma (Madura foot, maduromycosis)
North American blastomycosis (blastomycetic dermatitis, blastomycosis, Gilchrists disease)
Onychomycosis (dermatophytic onychomycosis, ringworm of the nail, tinea unguium)
Oral candidiasis (thrush)
Otomycosis
Perianal candidiasis
Perlèche (angular cheilitis)
Phaeohyphomycosis
Piedra (trichosporosis)
Pityrosporum folliculitis
Primary cutaneous aspergillosis
Primary cutaneous coccidioidomycosis
Primary cutaneous histoplasmosis
Primary pulmonary coccidioidomycosis
Primary pulmonary histoplasmosis
Progressive disseminated histoplasmosis
Proximal subungual onychomycosis
Rhinosporidiosis
South American blastomycosis (Brazilian blastomycosis, paracoccidioidal granuloma, paracoccidioidomycosis)
Sporotrichosis (rose-gardeners disease)
Systemic candidiasis
Tinea barbae (barbers itch, ringworm of the beard, tinea sycosis) 
Tinea capitis (herpes tonsurans, ringworm of the hair, ringworm of the scalp, scalp ringworm, tinea tonsurans)
Tinea corporis (ringworm, tinea circinata, tinea glabrosa)
Tinea corporis gladiatorum
Tinea cruris (crotch itch, eczema marginatum, gym itch, jock itch, ringworm of the groin)
Tinea faciei
Tinea imbricata (tokelau)
Tinea incognito
Tinea manuum
Tinea nigra (superficial phaeohyphomycosis, tinea nigra palmaris et plantaris)
Tinea pedis (athletes foot, ringworm of the foot)
Tinea versicolor (dermatomycosis furfuracea, pityriasis versicolor, tinea flava)
White piedra
White superficial onychomycosis
Zygomycosis (phycomycosis)

Parasitic infestations, stings, and bites
Parasitic infestations, stings, and bites in humans are caused by several groups of organisms belonging to the following phyla: Annelida, Arthropoda, Bryozoa, Chordata, Cnidaria, Cyanobacteria, Echinodermata, Nemathelminthes, Platyhelminthes, and Protozoa.