Dicloxacillin is a narrow-spectrum β-lactam antibiotic of the penicillin class. It is used to treat infections caused by susceptible (non-resistant) Gram-positive bacteria. It is active against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. Dicloxacillin is available under a variety of trade names including Diclocil (BMS).It was patented in 1961 and approved for medical use in 1968. Medical uses
Dicloxacillin is used to treat mild-to-moderate staphylococcal infections. To decrease the development of resistance, dicloxacillin is recommended to treat infections that are suspected or proven to be caused by beta-lactamase-producing bacteria.Dicloxacillin is similar in pharmacokinetics, antibacterial activity, and indications to flucloxacillin, and the two agents are considered interchangeable. It is believed to have lower incidence of severe hepatic adverse effects than flucloxacillin, but a higher incidence of renal adverse effects.Dicloxacillin is used for the treatment of infections caused by susceptible bacteria. Specific approved indications include:
Staphylococcal skin infections and cellulitis – including impetigo, otitis externa, folliculitis, boils, carbuncles, and mastitis
Pneumonia (adjunct)
Osteomyelitis, septic arthritis, throat infections, streptococcus
Septicaemia
Empirical treatment for endocarditis
Surgical prophylaxis

Available forms
Dicloxacillin is commercially available as the sodium salt, dicloxacillin sodium, in capsules and as a powder for reconstitution. Contraindications
Dicloxacillin is contraindicated in those with a previous history of allergy (hypersensitivity/anaphylactic reaction) to any penicillins.
APL is an abbreviation, acronym, or initialism that may refer to:

Science and technology
132524 APL, an asteroid
Abductor pollicis longus muscle, in the human hand
Acute promyelocytic leukemia, a subtype of acute myelogenous leukemia
Applied Physics Letters, a physics journal
Nampula Airport (IATA airport code: APL), in Mozambique

Computers
.apl, the file extension of the Monkeys Audio metadata file
AMD Performance Library, renamed Framewave, a computer compiler library
APL (programming language), an array-based programming language
APL (codepage), the character set for programming in APL
Address Prefix List, a DNS record type
Address programming language, an early high-level programming language developed in the Soviet Union
Advanced Physical Layer, an extension of Ethernet 10BASE-T1L for field devices
Alexa Presentation Language, a language for developing Amazon Alexa skills

Software licences
Adaptive Public License, an Open Source license from the University of Victoria, Canada
AROS Public License, a license of AROS Research Operating System
Arphic Public License, a free font license

Organizations
APL (shipping company), a Singapore-based container and shipping company
Aden Protectorate Levies, a militia force for local defense of the Aden Protectorate
Advanced Production and Loading, a Norwegian marine engineering company formed in 1993
Afghanistan Premier League, an Afghan Twenty20 cricket league
Afghan Premier League, a mens football league in Afghanistan
American Party of Labor, a Marxist-Leninist anti-revisionist party in the US
American Patriot League, a proposed American football spring league
American Premiere League, a Twenty20 cricket league in the US
American President Lines, a container transportation and shipping company
American Protective League, a World War I-era pro-war organization
Applied Physics Laboratory, at Johns Hopkins University
Association of Pension Lawyers, UK
Aurora Public Library (disambiguation)
Irish Anti-Partition League, a Northern Ireland political organisation

Other uses
apl.de.ap (born 1974), pseudonym of Allan Pineda Lindo, Filipino-American musician
Auxiliary Personal Living, a US Navy hull classification for barracks craft; see Auxiliary ship § Support