Newborns
There has been no established safety and effectiveness for use in premature infants and neonates. Elderly
No overall differences in safety or effectiveness were observed in clinical trials comparing elderly and younger subjects, however the trials could not eliminate the possibility that some older individuals may have a higher level of sensitivity. Additional considerations
People with kidney disease and those on hemodialysis may need the dose adjusted. Cefazolin levels are not significantly affected by liver disease. As with other antibiotics, cefazolin may interact with other medications being taken. Some important drugs that may interact with cefazolin such as probenecid. Side effects
Side effects associated with use of cefazolin therapy include:
Common (1-10%): diarrhea, stomach pain or upset stomach, vomiting, and rash. Uncommon (<1%): dizziness, headache, fatigue, itching, transient hepatitis.Patients with penicillin allergies could experience a potential reaction to cefazolin and other cephalosporins. As with other antibiotics, patients experiencing watery and/or bloody stools occurring up to three months following therapy should contact their prescriber.Like those of several other cephalosporins, the chemical structure of cefazolin contains an N-methylthiodiazole (NMTD or 1-MTD) side-chain. As the antibiotic is broken down in the body, it releases free NMTD, which can cause hypoprothrombinemia (likely due to inhibition of the enzyme vitamin K epoxide reductase) and a reaction with ethanol similar to that produced by disulfiram (Antabuse), due to inhibition of aldehyde dehydrogenase. Those with an allergy to penicillin may develop a cross sensitivity to cefazolin. Mechanism of action
Cefazolin inhibits cell wall biosynthesis by binding penicillin-binding proteins which stops peptidoglycan synthesis.
Zarah may refer to:

Zarah (television personality), a Filipino-American, also a singer
Zarah Garde-Wilson (born 1978), Australian solicitor
Zarah Ghahramani (born 1981), Iranian-born author living in Australia
Zarah Leander (1907 – 1981), Swedish actress and singer
Zarah, or Ich weiss, es wird einmal ein Wunder geschehen, a song by Nina Hagen
Fort Zarah

See also
Zahra (name)
Zara (disambiguation)
Zaraah Abrahams, English actress