Recurrent aphthous ulcers are common; however, it is not clear whether this is due to Crohns disease or simply that they are common in the general population. Other findings may include diffuse or nodular swelling of the mouth, a cobblestone appearance inside the mouth, granulomatous ulcers, or pyostomatitis vegetans. Medications that are commonly prescribed to treat CD, such as anti-inflammatory and sulfa-containing drugs, may cause lichenoid drug reactions in the mouth. Fungal infection such as candidiasis is also common due to the immunosuppression required in the treatment of the disease. Signs of anemia such as pallor and angular cheilitis or glossitis are also common due to nutritional malabsorption.People with Crohns disease are also susceptible to Angular Stomatitis, an inflammation of the corners of the mouth, and Pyostomatitis Vegetans. Systemic
Like many other chronic, inflammatory diseases, Crohns disease can cause a variety of systemic symptoms. Among children, growth failure is common. Many children are first diagnosed with Crohns disease based on inability to maintain growth. As it may manifest at the time of the growth spurt in puberty, up to 30% of children with Crohns disease may have retardation of growth. Fever may also be present, though fevers greater than 38.5 °C (101.3 °F) are uncommon unless there is a complication such as an abscess. Among older individuals, Crohns disease may manifest as weight loss, usually related to decreased food intake, since individuals with intestinal symptoms from Crohns disease often feel better when they do not eat and might lose their appetite.
Black heel and palm is a skin condition characterized by a sudden shower of minute, black, punctate macules occurring most often on the posterior edge of the plantar surface of one or both heels. : 43

See also
Skin lesion
List of cutaneous conditions


== References ==