Clinical signs and symptoms
According to a group case study, the most common symptoms in mild eosinophilic meningitis tend to be headache (with 100% of people in the study suffering from this symptom), photophobia or visual disturbance (92%), neck stiffness (83%), fatigue (83%), hyperesthesias (75%), vomiting (67%), and paresthesias (50%). Incubation period is often 3 weeks, but can be 3–36 days and even 80 days.Possible clinical signs and symptoms of mild and severe eosinophilic meningitis are:

Fever is often minor or absent, but the presence of high fever suggests severe disease. Headaches are progressive and severe, a bitemporal character in the frontal or occipital lobe. Meningismus - neck stiffness
Photophobia - sensitivity to light
Muscle weakness and fatigue
Nausea with or without vomiting
Paresthesias - tingling, prickling, or numbing of skin, may last for several weeks or months
Hyperesthesia - severe sensitivity to touch; may last for several weeks or months
Radiculitis - pain irradiated along certain areas of skin
Bladder dysfunction with urinary retention
Constipation
Brudzińskis sign
Vertigo
Blindness
Paralysis localized to one area; e.g. paralysis of extraocular muscles and facial palsy
General paralysis (flaccid) often ascending in nature starting with the feet and progressing upwards to involve the entire body
Coma
Death

Treatment
The severity and clinical course of Angiostrongylus disease depends significantly on the ingested load of third-stage larvae, creating great variability from case to case, making clinical trials difficult to design, and effectiveness of treatments difficult to discern. Typical conservative medical management including analgesics and sedatives provide minimal relief for the headaches and hyperesthesias.
Atypical lichen myxedematosus  is a skin condition caused by fibroblasts producing abnormally large amounts of mucopolysaccharides. : 186

See also
Lichen myxedematosus
Skin lesion

References


== External links ==