Transplanting skin derived from genetically modified stem cells onto the wound surfaces has been studied with a report of improvements in one person.A 2017 clinical trial with male RDEB (recessive dystrophic EB) patients conducted successful grafting of type VII gene corrected keratinocytes (COL7A1 gene correction using retrovirus transduction), without any serious adverse effects. Type VII collage formation was observed at the dermis-epidermis junction in significant amounts.A 2020 study demonstrated the safe allogenic grafting of acellular dermal matrix/scaffolds in EB patients without any observed infection or necrosis and instead noted fewer required dressing changes, promoted wound healing, pain reduction, and an overall improvement in the quality of life of the patients. Monitoring
The Epidermolysis Bullosa Disease Activity and Scarring index (EBDASI) is a scoring system that objectively quantifies the severity of EB. The EBDASI is a tool for clinicians and patients to monitor the severity of the disease. It has also been designed to evaluate the response to new therapies for the treatment of EB. The EBDASI was developed and validated by Professor Dedee Murrell and her team of students and fellows at the St George Hospital, University of New South Wales, in Sydney, Australia. It was presented at the International Investigative Dermatology congress in Edinburgh in 2013 and a paper-based version was published in the Journal of the American Academy of Dermatology in 2014. Prognosis
A 2014 study classified cases into three types—EBS, JEB and DEB—and reviewed their times of death. The first two types tended to die in infancy and the last in early adulthood.
The Mg2+ cation being the second most abundant cation in seawater and in rocksalt, the potential release of magnesium ions dissolving in brines intruding the deep geological repository is also expected to minimize the geochemical perturbations. MgO has an important place as a commercial plant fertilizer  and as animal feed. An aerosolized solution of MgO is used in library science and collections management for the deacidification of at-risk paper items. In this process, the alkalinity of MgO (and similar compounds) neutralizes the relatively high acidity characteristic of low-quality paper, thus slowing the rate of deterioration. MgO is also used as a protective coating in plasma displays. Magnesium oxide is used as an oxide barrier in spin-tunneling devices. Owing to the crystalline structure of its thin films, which can be deposited by magnetron sputtering, for example, it shows characteristics superior to those of the commonly used amorphous Al2O3. In particular, spin polarization of about 85% has been achieved with MgO versus 40–60 % with aluminium oxide. The value of tunnel magnetoresistance is also significantly higher for MgO (600% at room temperature and 1,100 % at 4.2 K) than Al2O3 (ca. 70% at room temperature). Precautions
Inhalation of magnesium oxide fumes can cause metal fume fever. See also
Calcium oxide
Barium oxide
Magnesium sulfide
Reactive magnesia

Notes
References
External links
Data page at UCL
Ceramic data page at NIST
NIOSH Pocket Guide to Chemical Hazards at CDC