However, IV urography has been largely replaced by contrast-enhanced, high-resolution helical CT with digital reconstruction. Treatment
Often, aggressive treatment is unnecessary for people with MSK disease that does not cause any symptoms (asymptomatic). In such cases, treatment may consist of maintaining adequate fluid intake, with the goal of decreasing the risk of developing kidney stones (nephrolithiasis). Cases of recurrent kidney stone formation may warrant evaluation for possible underlying metabolic abnormalities.In patients with low levels of citrate in the urine (hypocitraturia) and incomplete distal renal tubular acidosis, treatment with potassium citrate helps prevent the formation of new kidney stones. Urinary tract infections, when they occur, should also be treated.Patients with the more rare form of MSK marked by chronic pain typically require pain management. Non-obstructing stones in MSK can be associated with significant and chronic pain even if theyre not passing. It is not certain what causes this pain, but researchers have proposed that the small numerous stones seen in MSK may cause obstruction of the small tubules and collecting ducts in the kidney. This pain can be constant, can often be debilitating and treatment is challenging. Narcotic medication, even in large quantities, is sometimes not adequate. Some success with pain control has been reported using laser lithotripsy (called "ureteroscopic laser papillotomy"). Epidemiology
In the general population, the frequency of medullary sponge kidney disease is reported to be 0.02–0.005%; that is, 1 in 5000 to 1 in 20,000.
Juvenile plantar dermatosis  is a condition usually seen in children between the ages of 3 and 14, and involves the cracking and peeling of weight bearing areas of the soles of the feet. One of the earliest descriptions was made by British dermatologist Darrell Wilkinson. See also
Sulzberger–Garbe syndrome
List of cutaneous conditions

References


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