Further scratching may remove scabs, inhibiting the healing process. Scratching infected areas may also spread the fungus to the fingers and under the fingernails. If not washed away soon enough, it can infect the fingers and fingernails, growing in the skin and in the nails (not just underneath). After scratching, it can be spread to wherever the person touches, including other parts of the body and to ones environment. Scratching also causes infected skin scales to fall off into ones environment, leading to further possible spread. When athletes foot fungus or infested skin particles spread to ones environment (such as to clothes, shoes, bathroom, etc.) whether through scratching, falling, or rubbing off, not only can they infect other people, they can also reinfect (or further infect) the host they came from. For example, infected feet infest ones socks and shoes which further expose the feet to the fungus and its spores when worn again.The ease with which the fungus spreads to other areas of the body (on ones fingers) poses another complication. When the fungus is spread to other parts of the body, it can easily be spread back to the feet after the feet have been treated. And because the condition is called something else in each place it takes hold (e.g., tinea corporis (ringworm) or tinea cruris (jock itch)), persons infected may not be aware it is the same disease.
Allylamines such as terbinafine are considered more efficacious than azoles for the treatment of athletes foot.Severe or prolonged fungal skin infections may require treatment with oral antifungal medication. Topical treatments
There are many topical antifungal drugs useful in the treatment of athletes foot including: miconazole nitrate, clotrimazole, tolnaftate (a synthetic thiocarbamate), terbinafine hydrochloride, butenafine hydrochloride and undecylenic acid. The fungal infection may be treated with topical antifungal agents, which can take the form of a spray, powder, cream, or gel. Topical application of an antifungal cream such as butenafine once daily for one week or terbinafine once daily for two weeks is effective in most cases of athletes foot and is more effective than application of miconazole or clotrimazole. Plantar-type athletes foot is more resistant to topical treatments due to the presence of thickened hyperkeratotic skin on the sole of the foot. Keratolytic and humectant medications such as urea, salicyclic acid (Whitfields ointment), and lactic acid are useful adjunct medications and improve penetration of antifungal agents into the thickened skin. Topical glucocorticoids are sometimes prescribed to alleviate inflammation and itching associated with the infection.A solution of 1% potassium permanganate dissolved in hot water is an alternative to antifungal drugs. Potassium permanganate is a salt and a strong oxidizing agent. Oral treatments
For severe or refractory cases of athletes foot oral terbinafine is more effective than griseofulvin. Fluconazole or itraconazole may also be taken orally for severe athletes foot infections. The most commonly reported adverse effect from these medications is gastrointestinal upset.