It was patented in 1962 and first appeared in the literature in 1964. The drug was first introduced for the treatment of depression in 1966. Society and culture
Generic names
Protriptyline is the English and French generic name of the drug and its INN, BAN, and DCF, while protriptyline hydrochloride is its USAN, USP, and BANM. Its generic name in Spanish and Italian and its DCIT are protriptylina, in German is protriptylin, and in Latin is protriptylinum. Brand names
Protriptyline is or has been marketed throughout the world under a variety of brand names including Anelun, Concordin, Maximed, Triptil, and Vivactil. Availability
The sale of protriptyline was discontinued in the United Kingdom, Australia, and Ireland in 2000. == References ==
In 2012, crofelemer completed a Phase III trial, and it was approved in December 2012 by the FDA for the indication "symptomatic relief of non-infectious diarrhea in patients with HIV/AIDS on anti-retroviral therapy".The drug substance is manufactured by Glenmark Pharmaceuticals, and is manufactured as 125 mg delayed-release tablets by Patheon Pharmaceuticals Inc. for Napo Pharmaceuticals. References
External links
"Crofelemer". Drug Information Portal. U.S. National Library of Medicine.