The process is worsened if it is insufficient high-density lipoprotein (HDL), the lipoprotein particle that removes cholesterol from tissues and carries it back to the liver.The foam cells and platelets encourage the migration and proliferation of smooth muscle cells, which in turn ingest lipids, become replaced by collagen, and transform into foam cells themselves. A protective fibrous cap normally forms between the fatty deposits and the artery lining (the intima).These capped fatty deposits (now called atheromas) produce enzymes that cause the artery to enlarge over time. As long as the artery enlarges sufficiently to compensate for the extra thickness of the atheroma, then no narrowing ("stenosis") of the opening ("lumen") occurs. The artery becomes expanded with an egg-shaped cross-section, still with a circular opening. If the enlargement is beyond proportion to the atheroma thickness, then an aneurysm is created. Visible features
Although arteries are not typically studied microscopically, two plaque types can be distinguished:
The fibro-lipid (fibro-fatty) plaque is characterized by an accumulation of lipid-laden cells underneath the intima of the arteries, typically without narrowing the lumen due to compensatory expansion of the bounding muscular layer of the artery wall. Beneath the endothelium, there is a "fibrous cap" covering the atheromatous "core" of the plaque. The core consists of lipid-laden cells (macrophages and smooth muscle cells) with elevated tissue cholesterol and cholesterol ester content, fibrin, proteoglycans, collagen, elastin, and cellular debris.
Tongue-tie, tongue tied or tongue-tied can refer to:

ankyloglossia, a medical condition in which the lingual frenulum (a membrane that connects the tongue to the floor of the mouth) is unusually short, causing restricted movement of the tongue.Other uses include:

Literature
Tongue-Tied, a 1997 novel by Liselotte Marshall
Tongue-Tied (short story collection), a 2002 collection of short stories by Paul Jennings
"Tongue-Tied" a short story included in the collection
Tongue-Tied: How a Tiny String Under the Tongue Impacts Nursing, Speech, Feeding, and More, a 2018 non-fiction book by Dr. Richard Baxter

Music
Tongue Tied (Red Dwarf song), a song by Danny John-Jules in character as the Cat which was featured in the Red Dwarf episode "Parallel Universe" in 1988
"Tongue Tied" (Boom Crash Opera song), 1995
"Tongue-Tied", a song by Earshot from their 2004 album Two
"Tongue Tied" (Eve 6 song), a single from their 1998 album, Eve 6
"Tongue Tied" (Faber Drive song), 2007
"Tongue Tied" (Grouplove song), 2011
"Tongue Tied" (Marshmello, Yungblud and Blackbear song), 2019
"Tongue Tied", a song by Status Quo from their 2007 album In Search of the Fourth Chord

Other uses
Tongue-tie (tack), a piece of equipment sometimes used on racehorses
"Tongue-Tied" (Orange Is the New Black), a 2015 television episode
Miley Cyrus: Tongue Tied, a 2014 short film starring Miley Cyrus