The needle is inserted along the long axis, at a 30-degree angle, of the mesial or distal root for single rooted teeth and on the mesial and distal roots of multi-rooted teeth. Bevel orientation toward the root provides easier advancement of the needle apically. When the needle reaches between the root and crestal bone, significant resistance is experience. Anesthetic deposition is recommended at 0.2 mL, per root or site, over minimally 20 seconds. For its success, the anesthetic must be administered under pressure. It must not leak out of the sulcus into the mouth. Withdraw needle for minimally 10–15 seconds to permit complete deposition of solution. This can be slower than other injections as there is pressure build-up from the anesthetic administration. Blanching of the tissue is observed and may be more evident when vasoconstrictors are used. It is caused by a temporary obstruction of blood flow to the tissue.Syringes:

Standard syringes can be used. The intraligamentary syringe offers mechanical advantage by using a trigger-grasp or click apparatus to employ a gear or lever that improves control and results in increased force to push the anesthetic cartridges rubber stopper forward for medication deposition with greater ease. C-CLADs (computer controlled local anesthetic delivery devices) can be used. Its usage of computer microprocessors allows for control of fluid dynamics and anesthetic deposition. This minimizes subjective flow rates and variability in pressure.
Malignant triton tumor (MTT) is a relatively rare, aggressive tumor made up of both malignant schwannoma cells and malignant rhabdomyoblasts. It is classified as a malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation.The unusual name "triton" was first used in reference to observation of supernumerary limbs containing bone and muscle growing on the backs of triton salamanders after the implantation of sciatic nerve tissue. Diagnosis
There are three diagnostic criteria proposed:
The tumor arises along a peripheral nerve, or in a ganglioneuroma, or in a patient with neurofibromatosis type 1 (NF1), or has a metastatic character. The growth characteristics of the tumor is typical for a Schwann cell tumor. Rhabdomyoblasts arise within the body of the tumor. Treatment
References
Bibliography
Stasik CJ, Tawfik; Tawfik, O (2006). "Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor)". Arch Pathol Lab Med. 130 (12): 1878–81. doi:10.5858/2006-130-1878-MPNSTW. PMID 17149968.