These patents are in effect until dates ranging between July 17, 2018, and March 31, 2032.Novartis also maintains patents on nepafenac in 26 countries outside the United States. References
External links
"Nepafenac". Drug Information Portal. U.S. National Library of Medicine.
Diagnosis
Diagnosis of subacute bacterial endocarditis can be done by collecting three blood culture specimens over a 24-hour period for analysis, also it can usually be indicated by the existence of:

Oslers nodes
Roths spots
Nail clubbing

Treatment
The standard treatment is with a minimum of four weeks of high-dose intravenous penicillin with an aminoglycoside such as gentamicin. The use of high-dose antibiotics is largely based upon animal models.Leo Loewe of Brooklyn Jewish Hospital was the first to successfully treat subacute bacterial endocarditis with penicillin. Loewe reported at the time seven cases of subacute bacterial endocarditis in 1944. See also
Endocarditis

References
Further references
Goolsby, Mary Jo; Grubbs, Laurie (2011-04-28). Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses. F.A. Davis. ISBN 9780803625174. Silverman, Sol; Eversole, Lewis R.; Truelove, Edmond L. (2002-01-01). Essentials of Oral Medicine. PMPH-USA. ISBN 9781550091465. Kiefer, TL; Bashore, TM (2012). "Infective endocarditis: a comprehensive overview". Reviews in Cardiovascular Medicine. 13 (2–3): e105–20. PMID 23160159. == External links ==