Lymphangiomatosis is a condition where a lymphangioma is not present in a single localised mass, but in a widespread or multifocal manner. It is a rare type of tumor which results from an abnormal development of the lymphatic system.It is thought to be the result of congenital errors of lymphatic development occurring prior to the 20th week of gestation. Lymphangiomatosis is a condition marked by the presence of cysts that result from an increase both in the size and number of thin-walled lymphatic channels that are abnormally interconnected and dilated. 75% of cases involve multiple organs. It typically presents by age 20 and, although it is technically benign, these deranged lymphatics tend to invade surrounding tissues and cause problems due to invasion and/or compression of adjacent structures. The condition is most common in the bones and lungs and shares some characteristics with Gorham’s disease. Up to 75% of patients with lymphangiomatosis have bone involvement, leading some to conclude that lymphangiomatosis and Gorham’s disease should be considered as a spectrum of disease rather than separate diseases. When it occurs in the lungs, lymphangiomatosis has serious consequences and is most aggressive in the youngest children. When the condition extends into the chest it commonly results in the accumulation of chyle in the linings of the heart and/or lungs.Chyle is composed of lymph fluid and fats that are absorbed from the small intestine by specialized lymphatic vessels called lacteals during digestion.
Autoimmune
Multiple sclerosis (neurologic pain interpreted as muscular)
Myositis
Mixed connective tissue disease
Lupus erythematosus
Fibromyalgia syndrome
Familial Mediterranean fever
Polyarteritis nodosa
Devics disease
Morphea
Sarcoidosis

Metabolic defect
Carnitine palmitoyltransferase II deficiency
Conns syndrome
Adrenal insufficiency
Hyperthyroidism
Hypothyroidism
Diabetes
Hypogonadism
Postorgasmic illness syndrome

Other
Chronic fatigue syndrome (aka myalgic encephalomyelitis)
Channelopathy
Ehlers Danlos Syndrome
Stickler Syndrome
Hypokalemia
Hypotonia
Exercise intolerance
Mastocytosis
Peripheral neuropathy
Eosinophilia myalgia syndrome
Barcoo Fever
Herpes
Hemochromatosis
Delayed onset muscle soreness
HIV/AIDS
Generalized anxiety disorder
Tumor-induced osteomalacia
Hypovitaminosis D
Infarction

Withdrawal syndrome from certain drugs
Sudden cessation of high-dose corticosteroids, opioids, barbiturates, benzodiazepines, caffeine, or alcohol can induce myalgia. Treatment
When the cause of myalgia is unknown, it should be treated symptomatically. Common treatments include heat, rest, paracetamol, NSAIDs, massage, cryotherapy and muscle relaxants. See also
Arthralgia
Myopathy
Myositis

References


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