In 2006, a German research group analyzed family members of Wiskotts three cases, and surmised they probably shared a novel frameshift mutation of the first exon of the WASp gene. References
Further reading
GeneReviews/NIH/NCBI/UW entry on WAS-Related Disorders including Wiskott-Aldrich syndrome WAS X-linked thrombocytopenia XLT and X-linked congenital neutropenia XLN
Immune Deficiency Foundation - "Wiskott-Aldrich Syndrome"
Wiskott-Aldrich Foundation


== External links ==
Most facilities require that patients have a person with them to help them home afterwards (depending on the sedation method used). One common after-effect from the procedure is a bout of flatulence and minor wind pain caused by air insufflation into the colon during the procedure. An advantage of colonoscopy over X-ray imaging or other less invasive tests is the ability to perform therapeutic interventions during the test. A polyp is a growth of excess of tissue that can develop into cancer. If a polyp is found, for example, it can be removed by one of several techniques. A snare device can be placed around a polyp for removal. Even if the polyp is flat on the surface it can often be removed. For example, the following shows a polyp removed in stages:

Pain management
The pain associated with the procedure is not caused by the insertion of the scope but rather by the inflation of the colon in order to do the inspection. The scope itself is essentially a long, flexible tube about a centimeter in diameter — that is, as big around as the little finger, which is less than the diameter of an average stool. The colon is wrinkled and corrugated, somewhat like an accordion or a clothes-dryer exhaust tube, which gives it the large surface area needed for water absorption.