In making this decision, the FDA considered the potential risks associated with the drug, the life-threatening and debilitating nature of the disease, and the lack of available therapies.The application for viltolarsen was granted priority review designation and the FDA granted the approval to NS Pharma, Inc.

Society and culture
Economics
Viltolarsen costs around US$733,000 per year for a person that weighs 30 kilograms (66 lb). References
Further reading
Dhillon S (July 2020). "Viltolarsen: First Approval". Drugs. 80 (10): 1027–1031. doi:10.1007/s40265-020-01339-3. PMID 32519222. S2CID 219542850. Dzierlega K, Yokota T (June 2020). "Optimization of antisense-mediated exon skipping for Duchenne muscular dystrophy". Gene Ther. 27 (9): 407–416. doi:10.1038/s41434-020-0156-6. PMID 32483212. S2CID 219157034. Hwang J, Yokota T (October 2019). "Recent advancements in exon-skipping therapies using antisense oligonucleotides and genome editing for the treatment of various muscular dystrophies". Expert Rev Mol Med. 21: e5. doi:10.1017/erm.2019.5. PMID 31576784. S2CID 203641010. Roshmi RR, Yokota T (October 2019). "Viltolarsen for the treatment of Duchenne muscular dystrophy". Drugs Today. 55 (10): 627–639. doi:10.1358/dot.2019.55.10.3045038. PMID 31720560. S2CID 207935659. External links
"Viltolarsen". Drug Information Portal. U.S. National Library of Medicine (NLM). Clinical trial number NCT02740972 for "Safety and Dose Finding Study of NS-065/NCNP-01 in Boys With Duchenne Muscular Dystrophy (DMD)" at ClinicalTrials.gov
The prediction that childhood porencephaly is caused by hypercoagulable state, a condition where one has a higher chance of developing blood clots, was supported by the significance of the factor V G1691A mutation. Also, pregnant women in hypercoagulable state can cause the fetus to have the same risks, therefore possibly causing fetal loss, brain damage, lesions, and infections that lead to porencephaly. However, other different prothrombotic risk factors individually did not reach statistical significance to link it to the development of porencephaly, but a combination of multiple prothrombotic risk factors in the porencephaly group was significant. Overall, factor V G1691A mutation has been linked to the development of porencephaly. However, this one mutation is not the cause of porencephaly, and whether further prothrombiotic risk factors are associated with porencephaly still remains unknown. Cocaine and other street drugs
In utero exposure to cocaine and other street drugs can lead to porencephaly. Diagnostics
The presence of porencephalic cysts or cavities can be detected using trans-illumination of the skull of infant patients. Porencephaly is usually diagnosed clinically using the patients and families history, clinical observations, or based on the presence of certain characteristic neurological and physiological features of porencephaly. Advanced medical imaging with computed tomography (CT), magnetic resonance imaging (MRI), or with ultrasonography can be used as a method to exclude other possible neurological disorders. The diagnosis can be made antenatally with ultrasound. Other assessments include memory, speech, or intellect testing to help further determine the exact diagnose of the disorder.