Typically, the following triad of attack types appears; while the three types usually appear simultaneously, they also can occur independently of each other:
Lightning attacks: Sudden, severe myoclonic convulsions of the entire body or several parts of the body in split seconds, and the legs in particular are bent (flexor muscle convulsions here are generally more severe than extensor ones). Nodding attacks: Convulsions of the throat and neck flexor muscles, during which the chin is fitfully jerked towards the breast or the head is drawn inward. Salaam or jackknife attacks: a flexor spasm with rapid bending of the head and torso forward and simultaneous raising and bending of the arms while partially drawing the hands together in front of the chest and/or flailing. If one imagined this act in slow motion, it would appear similar to the Muslim ceremonial greeting (Salaam), from which this type of attack derives its name. Cause
It is still unknown which bio-chemical mechanisms lead to the occurrence of West syndrome. It is known to be a malfunction of neurotransmitter function, or more precisely, a malfunction in the regulation of the GABA transmission process. Another possibility being researched is a hyper-production of the corticotropin-releasing hormone (CRH). It is possible that more than one factor is involved. Both hypotheses are supported by the effect of certain medications used to treat West syndrome.Cases of epilepsy have been historically divided into three different groups: symptomatic, cryptogenic, and unknown.
Olmesartan/amlodipine/hydrochlorothiazide, sold under the brand name Tribenzor, is a fixed-dose combination medication used to treat high blood pressure. It contains olmesartan medoxomil, an angiotensin-2 receptor antagonist (ARB or A2A), amlodipine, a calcium channel blocker, and hydrochlorothiazide, a diuretic. It is taken by mouth. References
External links
"Amlodipine mixture with hydrochlorothiazide and olmesartan medoxomil". Drug Information Portal. U.S. National Library of Medicine.