BritLofex is only available by prescription. Lofexidine was first approved by the US FDA on May 16, 2018, under the brand name Lucemyra, produced by US WorldMeds. It was noted as the first, non-opioid drug approved in the US for the treatment of opioid withdrawal. See also
Methadone
Naltrexone
Clonidine


== References ==
Craniodiaphyseal dysplasia (CDD), also known as lionitis, is an extremely rare autosomal recessive bone disorder that causes calcium to build up in the skull, disfiguring the facial features and reducing life expectancy. These calcium deposits decrease the size of cranial foramina, and can decrease the circumference of the cervical spinal canal. In the few cases recorded, most died in childhood. Cause
The underlying genetics are uncertain. Diagnosis
Among the medical signs are dacryocystitis, seizures, intellectual disability, and paralysis, each of which is a complication resulting from the diminutive foramina. A common sign reported as a result of the disease has been widely spaced eyes. Society
Peter Bogdanovichs 1985 drama film Mask drew public attention to the case of Roy L. "Rocky" Dennis, an American boy who died of the disorder in 1978.In the American medical drama Greys Anatomy episode "Yesterday", Jesse Plemons plays a teenage boy with lionitis. The main character of the two-issue comic book miniseries Friday the 13th: How I Spent My Summer Vacation by Wildstorm Productions is a 13-year-old boy with the disorder. In the anthology television series American Horror Story season 1, Beauregard, the brother of Tate and Adelaide, had lionitis. See also
Leontiasis ossea

References
External links
Craniodiaphyseal dysplasia at orpha.net