In severe chronic kidney disease (GFR<30), the EMB dose should be halved (or avoided altogether). The PZA dose is 20 mg/kg/day (UK recommendation) or three-quarters the normal dose (US recommendation), but not much published evidence is available to support this. When using 2HRZ/4HR in patients on dialysis, the drugs should be given daily during the initial high-intensity phase. In the continuation phase, the drugs should be given at the end of each haemodialysis session and no dose should be taken on non-dialysis days. HIV
In patients with HIV, treatment for the HIV should be delayed until TB treatment is completed, if possible. The current UK guidance (provided by the British HIV Association) is

CD4 count over 200—delay treatment until the six months of TB treatment are complete. CD4 count 100 to 200—delay treatment until the initial two-month intensive phase of therapy is complete
CD4 count less than 100—the situation is unclear and patients should be enrolled in clinical trials examining this question. There is evidence that if these patients are managed by a specialist in both TB and HIV then outcomes are not compromised for either disease.If HIV treatment has to be started while a patient is still on TB treatment, then the advice of a specialist HIV pharmacist should be sought. In general, there is no significant interactions with the NRTIs. Nevirapine should not be used with rifampicin. Efavirenz may be used, but dose used depends on the patients weight (600 mg daily if weight less than 50 kg; 800 mg daily if weight greater than 50 kg).
Prevention
To prevent bringing home bed bugs, travelers are advised to take precautions after visiting an infested site: generally, these include checking shoes on leaving the site, changing clothes outside the house before entering, and putting the used clothes in a clothes dryer outside the house. When visiting a new lodging, it is advised to check the bed before taking suitcases into the sleeping area, and putting the suitcase on a raised stand to make bedbugs less likely to crawl in. An extreme measure would be putting the suitcase in the tub. Clothes should be hung up or left in the suitcase, and never left on the floor. Additional preventative measures include sealing cracks and crevices (which are often the sites of bed bug harborages), inspecting furniture, and for exposed travelers to decontaminate clothes and luggage upon returning home. The founder of a company dedicated to bedbug extermination said that 5% of hotel rooms he books into were infested. He advised people never to sit down on public transport; check office chairs, plane seats, and hotel mattresses; and monitor and vacuum home beds once a month. Close all wall openings or gaps; bed bugs tend to hide in dark places and cracked walls are a perfect spot for them to infest. Management
Treatment of bed bug bites requires keeping the person from being repeatedly bitten, and possible symptomatic use of antihistamines and corticosteroids (either topically or systemically).