In normal skin, the rate of production equals the rate of loss; about two weeks are needed for a cell to migrate from the basal cell layer to the top of the granular cell layer, and an additional two weeks to cross the stratum corneum. Dermis
The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis. The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone. Structural components of the dermis are collagen, elastic fibers, and ground substance also called extra fibrillar matrix. Within these components are the pilosebaceous units, arrector pili muscles, and the eccrine and apocrine glands. The dermis contains two vascular networks that run parallel to the skin surface—one superficial and one deep plexus—which are connected by vertical communicating vessels. The function of blood vessels within the dermis is fourfold: to supply nutrition, to regulate temperature, to modulate inflammation, and to participate in wound healing. Subcutaneous tissue
The subcutaneous tissue is a layer of fat between the dermis and underlying fascia. This tissue may be further divided into two components, the actual fatty layer, or panniculus adiposus, and a deeper vestigial layer of muscle, the panniculus carnosus. The main cellular component of this tissue is the adipocyte, or fat cell. The structure of this tissue is composed of septal (i.e. linear strands) and lobular compartments, which differ in microscopic appearance.
Microvasculitis refers to a range of diseases or presentations associated with a disease, where there is inflammation of small blood vessels:

Kawasaki disease
Susac syndrome

Nerve microvasculitis
Non-systemic vasculitic neuropathy (NSVN)
Hepatitis C-related cryoglobulinemia neuropathy (CRYOVASC)
Hepatitis B-associated PAN
Diabetic lumbosacral radiculoplexus neuropathy (DLRPN)
Non-diabetic lumbosacral radiculoplexus neuropathy (LRPN)
Diabetic cervical-radiculoplexus neuropathy (DCRPN)
Diabetic Cranio-Cervico-Radiculoplexus Neuropathy
Diabetic Cervical Neuropathy


== References ==