Dracunculiasis, also called Guinea-worm disease, is a parasitic infection by the Guinea worm, Dracunculus medinensis. A person becomes infected by drinking water containing water fleas infected with guinea worm larvae. The worms penetrate the digestive tract and escape into the body. Around a year later, the adult worm migrates to an exit site – usually a lower limb – and induces an intensely painful blister on the skin. The blister eventually bursts to form an intensely painful open wound, from which the worm slowly crawls over several weeks. The wound remains painful throughout the worms emergence, disabling the infected person for the three to ten weeks it takes the worm to emerge. During this time, the open wound can become infected with bacteria, leading to death in around 1% of cases.There is no medication to treat dracunculiasis. Instead, the mainstay of treatment is the careful wrapping of the emerging worm around a small stick to encourage its exit. Each day, a few more centimeters of the worm emerge, and the stick is turned to maintain gentle tension. With too much tension, the worm can break and die in the wound, causing severe pain and swelling at the ulcer site. Dracunculiasis is a disease of extreme poverty, occurring in places with poor access to clean drinking water. Prevention efforts center on filtering drinking water to remove water fleas, as well as public education campaigns to discourage people from soaking their emerging worms in sources of drinking water.
In 1981, the steering committee for the United Nations International Drinking Water Supply and Sanitation Decade (a program to improve global drinking water during the decade from 1981 to 1990) adopted the goal of eradicating dracunculiasis as part of their efforts. The following June, an international meeting termed "Workshop on Opportunities for Control of Dracunculiasis" concluded that dracunculiasis could be eradicated through public education, drinking water improvement, and larvicide treatments. In response, India began its national eradication program in 1983. In 1986, the 39th World Health Assembly issued a statement endorsing dracunculiasis eradication and calling on member states to craft eradication plans. The same year,  The Carter Center began collaborating with the government of Pakistan to initiate its national program, which then launched in 1988. By 1996, national eradication programs had been launched in every country with endemic dracunculiasis: Ghana and Nigeria in 1989; Cameroon in 1991; Togo, Burkina Faso, Senegal, and Uganda in 1992;  Benin, Mauritania, Niger, Mali, and Côte dIvoire in 1993; Sudan, Kenya, Chad, and Ethiopia in 1994; Yemen and the Central African Republic in 1995.Each national eradication program had three phases. The first phase consisted of a nationwide search to identify the extent of dracunculiasis transmission and develop national and regional plans of action. The second phase involved the training and distribution of staff and volunteers to provide public education village-by-village, surveil for cases, and deliver water filters. This continued and evolved as needed until the national burden of disease was very low.