Rarely, a Meckels diverticulum containing ectopic pancreatic tissue can present with abdominal pain and increased serum amylase levels, mimicking acute pancreatitis. Complications
The lifetime risk for a person with Meckels diverticulum to develop certain complications is about 4–6%. Gastrointestinal bleeding, peritonitis or intestinal obstruction may occur in 15–30% of symptomatic people (Table 1). Only 6.4% of all complications require surgical treatment, and untreated Meckels diverticulum has a mortality rate of 2.5–15%.Table 1 – Complications of Meckels Diverticulum:

Bleeding
Bleeding of the diverticulum is most common in young children, especially in males who are less than 2 years of age. Symptoms may include bright red blood in stools (hematochezia), weakness, abdominal tenderness or pain, and even anaemia in some cases.Bleeding may be caused by:

Ectopic gastric or pancreatic mucosa:Where diverticulum contains embryonic remnants of mucosa of other tissue types. Secretion of gastric acid or alkaline pancreatic juice from the ectopic mucosa leads to ulceration in the adjacent ileal mucosa i.e. peptic or pancreatic ulcer. Pain, bleeding or perforation of the bowel at the diverticulum may result. Mechanical stimulation may also cause erosion and ulceration.Gastrointestinal bleeding may be self-limiting but chronic bleeding may lead to iron deficiency anaemia.The appearance of stools may indicate the nature of the bleeding:

Tarry stools: Alteration of blood produced by slow bowel transit due to minor bleeding in upper gastrointestinal tract
Bright red blood stools: Brisk bleeding
Stools with blood streak: Anal fissure
"Currant jelly" stools: Ischaemia of the intestine leads to copious mucus production and may indicate that one part of the bowel invaginates into another intussusception.
Epidemiology
Meckels diverticulum occurs in about 2% of the population. Prevalence in males is 3–5 times higher than in females. Only 2% of cases are symptomatic, which usually presents among children at the age of 2.Most cases of Meckels diverticulum are diagnosed when complications manifest or incidentally in unrelated conditions such as laparotomy, laparoscopy or contrast study of the small intestine. Classic presentation in adults includes intestinal obstruction and inflammation of the diverticulum (diverticulitis). Painless rectal bleeding most commonly occurs in toddlers.Inflammation in the ileal diverticulum has symptoms that mimic appendicitis, therefore its diagnosis is of clinical importance. Detailed knowledge of the pathophysiological properties is essential in dealing with the life-threatening complications of Meckels diverticulum. References
External links
Meckels Diverticulum at eMedicine