The Tyrannosaurus rex specimen known as "Sue" is believed to have had gout. Research
A number of new medications are under study for treating gout, including anakinra, canakinumab, and rilonacept. Canakinumab may result in better outcomes than a low dose of a glucocorticoid, but costs five thousand times more. A recombinant uricase enzyme (rasburicase) is available but its use is limited, as it triggers an immune response. Less antigenic versions are in development. References
External links

Gout at Curlie
Chisholm, Hugh, ed. (1911). "Gout" . Encyclopædia Britannica. Vol. 12 (11th ed.). Cambridge University Press. pp. 289–291. "Gout". MedlinePlus. U.S. National Library of Medicine.
Crackles are much more common during the inspiratory than the expiratory phase of breathing, but they may be heard during the expiratory phase. Crackles are often associated with inflammation or infection of the small bronchi, bronchioles, and alveoli. Crackles that do not clear after a cough may indicate pulmonary edema or fluid in the alveoli due to heart failure, pulmonary fibrosis, or acute respiratory distress syndrome. Crackles that partially clear or change after coughing may indicate bronchiectasis. Crackles are often described as fine, medium, and coarse. They can also be characterized as to their timing: fine crackles are usually late-inspiratory, whereas coarse crackles are early inspiratory. Fine crackles are soft, high-pitched, and very brief. This sound can be simulated by rolling a strand of hair between ones fingers near the ears, or by moistening ones thumb and index finger and separating them near the ears. Their presence usually indicates an interstitial process, such as pulmonary fibrosis or congestive heart failure. The sounds from interstitial pulmonary fibrosis have been described as sounding like opening a Velcro fastener. Coarse crackles are somewhat louder, lower in pitch, and last longer than fine crackles. Their presence usually indicates an airway disease, such as bronchiectasis.They can also be described as unilateral or bilateral, as well as dry or moist/wet. See also
Bronchophony
Egophony
Consumption
Whooping cough
Croup
Pertussis toxin
Allergic asthma
Respiratory sounds

References
External links

Audio Breath Sounds - Multiple case studies with audio files of lung sounds. R.A.L.E. Repository - sound files of breath sounds