In Philippa Gregorys novel Wideacre (1987), the main character Beatrice Lacey nearly becomes addicted to laudanum when her eventual husband Dr. John MacAndrew prescribes it to her after her mothers death. In the adaptation Interview with the Vampire (1994), which was based on the 1976 novel with the same name, Claudia uses laudanum to try and dispose of Lestat: Under the pretext of making peace, she offers him some drunk noble-blood twins to feed on, when she actually had them overdosed with the said drug. In the film Tombstone (1993), Mattie Earp (Dana Wheeler-Nicholson), Wyatt Earps wife is addicted to laudanum. At the beginning of the film at the train station after her husband introduces her to his brothers and sisters-in-law she states, "Well, Wyatt, I couldnt find a single store that had laudanum anywhere." Her sister-in-law Louisa Earp (Lisa Collins) later said " Matter, Honey? Did you say you needed some laudanum? [...] I have some right here," hands Mattie a bottle and says, "Just be careful, now. Its full of hop," to which Mattie replies, "Oh, dont worry. I just get headaches sometimes." Later in the bedroom she and Wyatt shares, Mattie drinking out of a bottle, shows the effects of laudanum, hiding the bottle as Wyatt enters the bedroom asking, "Is that the opium Lou gave you? Its a new bottle, isnt it?
An electrocardiogram (ECG) undertaken during an episode of AVRT demonstrates typical features of retrograde (inverted) p-waves in the inferior leads II, III, aVF, and V4–V6 with a long RP′ interval. The P:QRS ratio would be 1:1 and they would be narrow complexes. Treatment
Termination of an episode of AVRT in PJRT can be achieved with vagal manouvres, antiarrhythmic medications or DC cardioversion. Long-term management is best achieved with catheter ablation. Prognosis
Without treatment, the prevalence of tachycardia-induced cardiomyopathy has been reported to be between 20% and 50%, however most patients who undergo ablation have significant improvement in their cardiac function 


== References ==