As a result, the World Health Organization currently takes into account both molecular genetics and morphology to classify rhabdomyosarcoma into the embryonal, alveolar, spindle cell/sclerosing, and pleomorphic subtypes.When examining Embroynal Rhabdomyosarcoma tumors vs. Alveolar Rhabdomyosarcoma tumors, a 2013 study had discovered that there were more rates of mutation in ERMS tumors. The study had use whole genome sequencing to sequence the DNA from 16 RMS tumors and found that RAS pathway mutations tend to be more associated with intermediate and high risk embryonal Rhabdomyosarcoma. Additionally, Embryonal Rhabdomyosarcoma tends to be more common in males versus females, with an occurrence of 1.4:1. Histology
Embryonal rhabdomyosarcoma has been informally classified as a "small round blue cell tumor" because of the characteristic microscopic appearance of its cells after histological staining with hematoxylin and eosin. Histologically, embryonal rhabdomyosarcoma commonly presents as alternating loose and dense patches of cells, including round cell and spindle cell components. The heterogenous structure resembles striated muscle at various embryonal developmental stages. Location
Embryonal rhabdomyosarcoma can develop in soft tissues throughout the body, however, it is commonly found in the "head and neck area or in the genital or urinary organs"  The botryoid variant of ERMS occurs in mucosal-lined organs such as the common bile duct, bladder, and vagina. The etymology for this variant name comes from "grape clusters", referring to the gross appearance of grape-like masses. Epidemiology of RMS
RMS has a higher incidence of affecting males compared to females.
Surgical therapies include:

Distal and proximal osteotomies of the 5th metatarsal can be used to correct the intermetatarsal and metatarsophalangeal angle causing the TB. Diagnosis
Tailors bunion is easily diagnosed because the protrusion is visually apparent. X-rays may be ordered to help the surgeon find out the severity of the deformity. Types of Tailors bunions
Type 1: The head of the 5th metatarsal is thickened and enlarged. Type 2: A 5th metatarsal with an increased lateral curve and a normal fourth and fifth inter-metatarsal angle. Type 3: Has the greatest lateral angular disposition of the 5th metatarsal compared to the 4th metatarsal, this phenomenon increases the 4th and 5th inter-metatarsal angles. This is generally the most symptomatic type of Tailors bunion. Type 4: A combination of at least two types of bunionettes (TB). Lesser toe deformities leading to falls
Five studies examined associations between falls and foot disorders. Significant associations were found between falls and plantar fasciitis, corns or bunions and lesser toe deformity (such as Tailors bunions). The results of these studies show that "Older people who fell were more likely to have foot pain, hallux valgus, and lesser toe deformity". See also

Tailors muscle
Bunion, also known as hallux valgus, a similar condition of the big toe. == References ==