The unique frontal lobe cognitive changes of progressive supranuclear palsy (apathy, loss of spontaneity, slowing of thought processes, and loss of executive functions) were first described by Albert and colleagues in 1974. Society and culture
There are several organizations around the world that support PSP patients and the research into PSP and related diseases, such as corticobasal degeneration (CBD) and multiple system atrophy (MSA). Canada: PSP Society of Canada, a federally registered non-profit organization which serves patients and families dealing with PSP, CBD and MSA, set up in 2017 through the help of CurePSP in the USA
France: Association PSP France, a nonprofit patient association set up in 1996 through the help of PSPA in the UK. It also gives support to French speaking patients in Quebec, Morocco, Algeria, Belgium and Lebanon
UK: PSPA, a national charity for information, patient support and research of PSP and CBD, set up in 1995
Ireland: PSPAI, a body which aims to get PSP better known
US: CurePSP, a nonprofit organization for promoting awareness, care and research of PSP, CBD, MSA "and other prime of life neurodegenerative diseases"

In popular culture
In the 2020 American musical comedy-drama television series, Zoeys Extraordinary Playlist, the title characters father (Mitch Clarke, played by Peter Gallagher) has PSP and dies in the final episode of the first season.American singer Linda Ronstadt was diagnosed with PSP in 2019, subsequent to an initial diagnosis of Parkinsons disease in 2014. See also
Lytico-bodig disease (Parkinsonism-Dementia Complex of Guam)
Annonacin


== References ==
Multiple evanescent white dot syndrome (MEWDS) is an uncommon inflammatory condition of the retina that typically affects otherwise healthy young females in the second to fourth decades of life. The typical patient with MEWDS is a healthy middle aged female age 15-50. There is a gender disparity as women are affected with MEWDS four times more often than men. Roughly 30% of patients have experienced an associated viral prodrome. Patients present with acute, painless, unilateral change in vision. Presentation
Patients commonly present with acute unilateral painless decreased vision and photopsias. Presentations like central or paracentral scotoma, Floaters and dyschromatopsia are less common. An antecedent viral prodrome occurs in approximately one-third of cases. Myopia is commonly seen in patients. Eye exam during the acute phase of the disease reveals multiple discrete white to orange spots at the level of the RPE or deep retina, typically in a perifoveal location (around the fovea). Optic disc oedema may also seen occasionally. Cause
The etiology of multiple evanescent white dot syndrome is currently unknown. However, it is associated with the Pfizer vaccine according to the Jerusalem Post, August 4, 2021. Diagnosis
Visual field abnormalities are variable and include generalized depression of visual field, paracentral or peripheral scotoma and enlargement of the blind spot. Fluorescein angiography of the eye reveals characteristic punctate hyperfluorescent lesions in a wreath-like configuration surrounding the fovea. Indocyanine green angiography reveals hypofluorescent lesions in a greater number compared with other studies. Fundus autofluorescence (FAF) has been shown to be a noninvasive method to demonstrate the subretinal spots in MEWDS.