Interrupted aortic arch is a very rare heart defect (affecting 3 per million live births) in which the aorta is not completely developed. There is a gap between the ascending and descending thoracic aorta. In a sense it is the complete form of a coarctation of the aorta. Almost all patients also have other cardiac anomalies, including a ventricular septal defect (VSD), aorto-pulmonary window, and truncus arteriosus. There are three types of interrupted aortic arch, with type B being the most common. Interrupted aortic arch (especially Type B) is often associated with DiGeorge syndrome. Signs and symptoms
Patients with an interrupted aortic arch usually have symptoms from birth, with nearly all presenting symptoms within two weeks (when the ductus arteriosus is usually closed). Causes
It is thought that an interrupted aortic arch occurs through excessive apoptosis in the developing, embryonic aorta. Around 50% of patients have DiGeorge syndrome. Diagnosis
It can be diagnosed with a standard echocardiogram. An echocardiogram can also aid in classifying the type of defect. The diagnosis can also be made prior to birth via ultrasound. Patients will have a loss of appetite, appear tired and weak, and exhibit rapid breathing and a rapid heart rate. If the condition progresses, the infant may turn pale, feel cold in the lower half of the body, and have a weak pulse due to insufficient blood flow.
Yaz may refer to:

People
Yazmith Bataz (born 1972), Mexican sprinter
Yaz Mubarakai (born 1975), Australian politician
Carl Yastrzemski (born 1939), American Hall-of-Fame baseball player
Mike Yastrzemski (born 1990), American professional baseball player, grandson of Carl

Other uses
Yaz culture, an early Iron Age culture of Bactria and Margiana, c. 1500-1100 BC
Yaz-class river patrol craft, Russian Coast Guard vessels
YAZ, IATA code for Tofino Airport in Tofino, British Columbia, Canada
yaz, ISO 639-3 code for the Yakö language, spoken by the Yakö people of Nigeria
Yaz (band) or  Yazoo, an English synth-pop band
Yaz Pistachio, a female character from the comic strip Bloom County
Yaz (drug), a brand name for a birth control pill containing drospirenone that may also be used for other indications
YAZ, a programmer toolkit for development of Z39.50 clients and servers

See also
Yazz (born 1960), pseudonym used by English singer Yasmin Evans
Yazz The Greatest, a stage name of American actor and rapper Bryshere Y. Gray