5 (5): CD006685. doi:10.1002/14651858.CD006685.pub4. PMC 7386458. PMID 27153153. Pearce, J. M. (2008). "Kleine–Levin Syndrome: History and Brief Review". European Neurology. 60 (4): 212–4. doi:10.1159/000148694. PMID 18667831. Ramdurg, Santosh (2010). "Kleine–Levin Syndrome: Etiology, Diagnosis, and Treatment". Annals of Indian Academy of Neurology. 13 (4): 241–6. doi:10.4103/0972-2327.74185. PMC 3021925. PMID 21264130. External links

kleine_levin at NINDS
Story of young man with Kleine–Levin syndrome at The New York Times
Also, the rate of lymphocytic infiltration increased in areas where the iodine intake was once low, but increased due to iodine supplementation. "The prevalence of positive serum tests in such areas rises to over 40 percent within 0.5 to 5 years." Age
It has been shown that "the prevalence of positive tests for thyroid antibodies increases with age, with a frequency as high as 33 percent in women 70 years old or older." The mean age of prevalence in women is higher than in men by one year, (58 and 59 years old respectively).Autoimmune thyroiditis can affect children. It is very rare in children under the age of five, but can occur; it accounts for around 40 percent of cases in adolescents with goiters.People with hypothyroidism over the age of 40 have an increased chance of developing autoimmune thyroiditis. Mechanism
Thyroid autoantibodies appear mostly with the presence of lymphocytes in the targeted organ. Lymphocytes produce antibodies targeting three different thyroid proteins: Thyroid peroxidase Antibodies (TPOAb), Thyroglobulin Antibodies (TgAb), and Thyroid stimulating hormone receptor Antibodies (TRAb). The antibody attacks ultimately lead to hypothyroidism, which is caused by replacement of follicular cells with parenchymatous tissue.Some patients who are healthy may be positive for more than one of these antibodies. Doctors who attend to such patients will most likely do routine follow-ups on the patients health since, even though it is highly unlikely that they will present any thyroid problems, there is still a chance that they will develop some type of dysfunction with time.