Binge eating habits are often associated  with changes in food preferences (cravings for more sweets, carbohydrates), eating inedible objects and snatching food from others. Recent findings from structural MRI research have indicated that eating changes in FTD are associated with atrophy (wasting) in the right ventral insula, striatum, and orbitofrontal cortex.People with FTD show marked deficiencies in executive functioning and working memory. Most become unable to perform skills that require complex planning or sequencing. In addition to the characteristic cognitive dysfunction, a number of primitive reflexes known as frontal release signs are often able to be elicited. Usually the first of these frontal release signs to appear is the palmomental reflex which appears relatively early in the disease course whereas the palmar grasp reflex and rooting reflex appear late in the disease course.In rare cases, FTD can occur in people with amyotrophic lateral sclerosis (ALS) a motor neuron disease. The prognosis for people with ALS is worse when combined with FTD, shortening survival by about a year. Genetics
A higher proportion of frontotemporal dementias seem to have a familial component than other neurodegenerative diseases such as Alzheimers disease. More and more mutations and genetic variants are being identified all the time, needing constant updating of genetic influences. Tau-positive frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) is caused by mutations in the MAPT gene on chromosome 17 that encodes the tau protein. It has been determined that there is a direct relationship between the type of tau mutation and the neuropathology of gene mutations.
Kevin Moore (1958–2013), English footballer
Pat Moran (1947–2011), British record producer, singer and Mellotron player with progressive rock band Spring
Ernie Moss (1949–2021), English footballer
Nic Potter (1951–2013), British bassist for Van der Graaf Generator
Christina Ramberg (1946–1995), American painter associated with the Chicago Imagists
David Rumelhart (1942–2011), American cognitive psychologist
Colin Savage, father of footballer Robbie Savage
Sir Nicholas Wall (1945–2017), English judge
Mark Wirtz (1943–2020), pop musician, composer and producer

See also
References
Further reading
External links
OMIM on Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis and Chromosome 9 Open Reading Frame 72; C9ORF72