Vaccinations
People with RA have an increased risk of infections and mortality and recommended vaccinations can reduce these risks. The inactivated influenza vaccine should be received annually. The pneumococcal vaccine should be administered twice for people under the age 65 and once for those over 65. Lastly, the live-attenuated zoster vaccine should be administered once after the age 60, but is not recommended in people on a tumor necrosis factor alpha blocker. Prognosis
The course of the disease varies greatly. Some people have mild short-term symptoms, but in most the disease is progressive for life. Around 25% will have subcutaneous nodules (known as rheumatoid nodules); this is associated with a poor prognosis. Prognostic factors
Poor prognostic factors include,

Persistent synovitis
Early erosive disease
Extra-articular findings (including subcutaneous rheumatoid nodules)
Positive serum RF findings
Positive serum anti-CCP autoantibodies
Positive serum 14-3-3η (YWHAH) levels above 0.5 ng/ml 
Carriership of HLA-DR4 "Shared Epitope" alleles
Family history of RA
Poor functional status
Socioeconomic factors
Elevated acute phase response (erythrocyte sedimentation rate [ESR], C-reactive protein [CRP])
Increased clinical severity. Mortality
RA reduces lifespan on average from three to twelve years. Young age at onset, long disease duration, the presence of other health problems, and characteristics of severe RA—such as poor functional ability or overall health status, a lot of joint damage on x-rays, the need for hospitalisation or involvement of organs other than the joints—have been shown to associate with higher mortality. Positive responses to treatment may indicate a better prognosis.
Hidrocystoma (also known as cystadenoma, a Molls gland cyst, and a sudoriferous cyst) is an adenoma of the sweat glands. : 787 Hidrocystomas are cysts of sweat ducts, usually on the eyelids. : 664  They are not tumours (a similar-sounding lesion called hidroadenoma is a benign tumour). The three types of "sweat" glands are: True sweat glands or eccrine glands, sebaceous glands, which have an oily secretion around hair follicles, and apocrine glands, which have more oily product than eccrine glands and are found on the face, armpit, and groin. Hidrocystomas usually arise from apocrine glands. They are also called cysts of Moll or sudoriferous cysts. A type of hidroadenoma that arises from eccrine glands is uncommon. Other related conditions on the eyelids include chalazion (a granulomatous reaction to sebaceous glands on the eyelid), lacrimal duct cysts (cysts related to tear ducts), and nasolacrimal duct cysts (the nasolacrimal duct drains tears into the nose via a punctum on the lower eyelid). Additional images
See also
Syringoma
Acrospiroma
Seborrheic keratosis
List of cutaneous conditions
List of cutaneous neoplasms associated with systemic syndromes

References


== External links ==