Many people who present with secondary syphilis (40–85% of women, 20–65% of men) do not report previously having had the classical chancre of primary syphilis. Latent
Latent syphilis is defined as having serologic proof of infection without symptoms of disease. It develops after secondary syphilis and is divided into early latent and late latent stages. Early latent syphilis is defined by the World Health Organization as less than 2 years after original infection. Early latent syphilis is infectious as up to 25% of people can develop a recurrent secondary infection (during which spirochetes are actively replicating and are infectious). Two years after the original infection the person will enter late latent syphilis and is not as infectious as the early phase. The latent phase of syphilis can last many years after which, without treatment, approximately 15-40% of people can develop tertiary syphilis. Tertiary
Tertiary syphilis may occur approximately 3 to 15 years after the initial infection, and may be divided into three different forms: gummatous syphilis (15%), late neurosyphilis (6.5%), and cardiovascular syphilis (10%). Without treatment, a third of infected people develop tertiary disease. People with tertiary syphilis are not infectious.Gummatous syphilis or late benign syphilis usually occurs 1 to 46 years after the initial infection, with an average of 15 years. This stage is characterized by the formation of chronic gummas, which are soft, tumor-like balls of inflammation which may vary considerably in size. They typically affect the skin, bone, and liver, but can occur anywhere.Cardiovascular syphilis usually occurs 10–30 years after the initial infection.
We deeply regret that it happened, and we apologize to all the individuals who were affected by such abhorrent research practices." The experiments were led by physician John Charles Cutler who also participated in the late stages of the Tuskegee syphilis experiment. Names
It was first called grande verole or the "great pox" by the French. Other historical names have included "button scurvy", sibbens, frenga and dichuchwa, among others. Since it was a disgraceful disease, the disease was known in several countries by the name of their neighbouring country. The English, the Germans, and the Italians called it "the French disease", while the French referred to it as the "Neapolitan disease". The Dutch called it the "Spanish/Castilian disease". To the Turks it was known as the "Christian disease", whilst in India, the Hindus and Muslims named the disease after each other. References
Further reading
Ghanem KG, Ram S, Rice PA (February 2020). "The Modern Epidemic of Syphilis". N. Engl. J. Med. 382 (9): 845–54. doi:10.1056/NEJMra1901593. PMID 32101666. S2CID 211537893. Ropper AH (October 2019). "Neurosyphilis". N. Engl. J. Med. 381 (14): 1358–63. doi:10.1056/NEJMra1906228. PMID 31577877. S2CID 242487360. External links

"Syphilis - CDC Fact Sheet" Centers for Disease Control and Prevention (CDC)
UCSF HIV InSite Knowledge Base Chapter: Syphilis and HIV Archived 20 January 2013 at the Wayback Machine
Recommendations for Public Health Surveillance of Syphilis in the United States 
Pastuszczak, M.; Wojas-Pelc, A. (2013). "Current standards for diagnosis and treatment of syphilis: Selection of some practical issues, based on the European (IUSTI) and U.S. (CDC) guidelines". Advances in Dermatology and Allergology.