It has also been noted that the timing of the operation, plays a role in survival, it is preferable to delay the surgery if possible (6 hours in cases of nontransmural MI, 3 days in cases of transmural MI)CABG of coronary lesions is also indicated in mechanical complications of an infarction (ventricular septal defect, papillary muscle rupture or myocardial rupture) should be addressed There are no absolute contraindications of CABG but severe disease of other organs such as liver or brain, limited life expectancy, fragility should be taken into consideration when planning the treatment path of a patient. Other cardiac surgery
CABG is also performed when a patient is to undergo another cardiac surgical procedure, most commonly for valve disease, and at angiography a significant lesion of the coronaries is found. CABG can be employed in other situations other than atheromatic disease of native heart arteries, like for the dissection of coronary arteries (where a rupture of the coronary layers creates a pseudo-lumen and diminishes blood delivery to the heart) caused e.g. by pregnancy, tissue diseases as Enhler-Danlos, Marfan Syndrome, cocaine abuse or Percutaneous Coronary Intervention). A coronary aneurysm is another reason for CABG, for a thrombus might develop within the vessel, and  possibly travel further. CABG vs PCI
CABG and percutaneous coronary intervention (PCI) are the two modalities the medical community has to revascularize stenotic lesions of the cardiac arteries.
LIMA to LAD is performed in the operating theatre and other lesions are treated with PCI, either at the operating room, right after the anastomosis or serval days later. After the procedure
After the procedure, the patient is usually transferred to the intensive care unit, where they are extubated if it hasnt been done already in the operating theatre. The following day they exit the ICU, and 4 days later, if no complications occur, the patient is discharged from the hospital.A series of drugs are commonly used in the early postoperative period. Dobutamine, a beta agent, can be used to increase the cardiac output that sometimes occurs some hours after the operation. Beta blockers are used to prevent atrial fibrillation and other supraventricular arrhythmias. Biatrial pacing through the pacing wires inserted at operation might help towards preventing atrial fibrillation. Aspirin 80mg is used to prevent graft failure. Angiotensin-converting enzyme (ACE) inhibitors and Angiotensin receptor blockers (ARBs) are used to control blood pressure, especially in patients with low cardiac function (<40%). Amlodipine, a calcium channel blocker, is used for patients that radial artery was used as a graft.After the discharge, patients might suffer from insomnia, low appetite, decreased sex drive, and memory problems. This effect is usually transient and lasts 6 to 8 weeks. A tailored exercise plan usually benefits the patient. Results
CABG is the best procedure to reduce mortality from severe CAD and improve quality of life. Operative mortality relates strongly to age of patient.