A few possible treatment options are to reconstruct the nose with a forehead flap or reconstruct the nasal dorsum with a bone graft, for example a rib graft. The nasal reconstruction with a forehead flap is based on the repositioning of a skin flap from the forehead to the nose. A possible downside of this reconstruction is that once you performed it at a younger age, you can’t lengthen the flap at a later stage. A second operation is often needed if the operation is done on early age, because the nose has a restricted growth in the cleft area. Repair of the ala (wing of the nose) often requires the inset of cartilage graft, commonly taken from the ear. Treatment of midface anomalies
The treatment of soft tissue parts of midface anomalies is often a reconstruction from a skin flap of the cheek. This skinflap can be used for other operations in the further, as it can be raised again and transposed again. In the treatment of midface anomalies there are generally more operations needed. Bone tissue reconstruction of the midface often occurs later than the soft tissue reconstruction. The most common method to reconstruct the midface is by using the fracture/ incision lines described by René Le Fort. When the cleft involves the maxilla, it is likely that the impaired growth will result in a smaller maxillary bone in all 3 dimensions (height, projection, width). Treatment of mouth anomalies
There are several options for treatment of mouth anomalies like Tessier cleft number 2-3-7 .
To date, two population-based nationwide studies have been conducted both estimating a prevalence about 1 in 5,000 live female births. According to some reports, Queen Amalia of Greece may have had the syndrome, but a 2011 review of the historical evidence concludes that it is not possible to determine the inability of her and her husband to have a child. Their inability to conceive an heir contributed to the overthrow of the king King Otto. People with MRKH
Ben Barres, transgender male scientist
Esther Morris Leidolf, medical sociologist and intersex activist
Stephanie Lum, Australian intersex activist
Shon Klose, Australian intersex activist and musician
Jaclyn Schultz, Miss Michigan

Suspected cases
Eva Braun
Amalia of Oldenburg

See also
MURCS association
Cervical agenesis
WNT4 deficiency
SERKAL syndrome
Regenerative medicine
MRKH AUSTRIA

References
Further reading
External links
Online Mendelian Inheritance in Man (OMIM): 277000
American College of Obstetricians and Gynecologists, Müllerian Agenesis: Resource Overview