Oral agents
Aspirin
Clopidogrel
Cilostazol
Ticlopidine
Ticagrelor
Prasugrel

Drugs that stimulate platelet production
Thrombopoietin mimetics
Desmopressin
Factor VIIa

Intravenous agents
Abciximab
Eptifibatide
Tirofiban
Others: oprelvekin, romiplostim, eltrombopag, argatroban

Therapy with platelets
Transfusion
Indications
Platelet transfusion is most frequently used to correct unusually low platelet counts, either to prevent spontaneous bleeding (typically at counts below 10×109/L) or in anticipation of medical procedures that will necessarily involve some bleeding. For example, in patients undergoing surgery, a level below 50×109/L is associated with abnormal surgical bleeding, and regional anaesthetic procedures such as epidurals are avoided for levels below 80×109/L. Platelets may also be transfused when the platelet count is normal but the platelets are dysfunctional, such as when an individual is taking aspirin or clopidogrel. Finally, platelets may be transfused as part of a massive transfusion protocol, in which the three major blood components (red blood cells, plasma, and platelets) are transfused to address severe hemorrhage. Platelet transfusion is contraindicated in thrombotic thrombocytopenic purpura (TTP), as it fuels the coagulopathy. Collection
Platelets are either isolated from collected units of whole blood and pooled to make a therapeutic dose, or collected by platelet apheresis: blood is taken from the donor, passed through a device which removes the platelets, and the remainder is returned to the donor in a closed loop. The industry standard is for platelets to be tested for bacteria before transfusion to avoid septic reactions, which can be fatal.
As a result, pingueculae tend to occur more often on the nasal side of the eye. While most pingueculae are found in people over the age of 40, they are not uncommon in 20- and 30-year-old adults who spend significant time in the sun. The surface of the conjunctival tissue overlying a pinguecula interferes with the normal spreading of the tear film. The tear ferning test reveals abnormalities of the mucous component of the tear film, making it useful as a predictor of a persons tolerance of hydrophilic soft contact lenses. Contact lens intolerance can also result from the elevation of the peripheral edge of the contact lens if it overlies a pinguecula. The plural form of pinguecula is pingueculae. Pinguecula is derived from the Latin word "pinguis" for fat or grease. Associated conditions
A pinguecula is one of the differential diagnoses for a limbal nodule. It may have an increased prevalence in Gauchers disease. Diagnosis
Diagnosis of pinguecula is usually done by an eye care professional during routine eye examination using slit lamp. Conjunctival biopsy may be advised if malignancy is suspected. Treatment
Pingueculae may enlarge slowly over time, but are a benign condition, usually requiring no treatment. Artificial tears may help to relieve discomfort, if it occurs. If cosmesis is a concern, or if there is discomfort in contact lens use, surgical excision may be done. Occasionally, a pinguecula may become inflamed, a condition called pingueculitis. The cause of pingueculitis is unknown and there are no known infectious agents associated with it.