Diverticulitis
Inflammation of the diverticulum can mimic symptoms of appendicitis, i.e., periumbilical tenderness and intermittent crampy abdominal pain. Perforation of the inflamed diverticulum can result in peritonitis. Diverticulitis can also cause adhesions, leading to intestinal obstruction.Diverticulitis may result from:

Association with the mesodiverticular band attaching to the diverticulum tip where torsion has occurred, causing inflammation and ischaemia. Peptic ulceration resulting from ectopic gastric mucosa of the diverticulum
Following perforation by trauma or ingested foreign material e.g. stalk of vegetable, seeds or fish/chicken bone that become lodged in Meckels diverticulum. Luminal obstruction due to tumors, enterolith, foreign body, causing stasis or bacterial infection. Association with acute appendicitis

Intestinal obstruction
Symptoms: Vomiting, abdominal pain and severe or complete constipation. The vitelline vessels remnant that connects the diverticulum to the umbilicus may form a fibrous or twisting band (volvulus), trapping the small intestine and causing obstruction. Localised periumbilical pain may be experienced in the right lower quadrant (like appendicitis). "Incarceration": when a Meckels diverticulum is constricted in an inguinal hernia, forming a Littré hernia that obstructs the intestine. Chronic diverticulitis causing stricture
Strangulation of the diverticulum in the obturator foramen. Tumors e.g. carcinoma: direct spread of an adenocarcinoma arising in the diverticulum may lead to obstruction
Lithiasis, stones that are formed in Meckels diverticulum can:Extrude into the terminal ileum, leading to obstruction
Induce local inflammation and intussusception.The diverticulum itself or tumour within it may cause intussusception. For example, from the ileum to the colon, causing obstruction. Symptoms of this include "currant jelly" stools and a palpable lump in the lower abdomen.
Epidemiology
Meckels diverticulum occurs in about 2% of the population. Prevalence in males is 3–5 times higher than in females. Only 2% of cases are symptomatic, which usually presents among children at the age of 2.Most cases of Meckels diverticulum are diagnosed when complications manifest or incidentally in unrelated conditions such as laparotomy, laparoscopy or contrast study of the small intestine. Classic presentation in adults includes intestinal obstruction and inflammation of the diverticulum (diverticulitis). Painless rectal bleeding most commonly occurs in toddlers.Inflammation in the ileal diverticulum has symptoms that mimic appendicitis, therefore its diagnosis is of clinical importance. Detailed knowledge of the pathophysiological properties is essential in dealing with the life-threatening complications of Meckels diverticulum. References
External links
Meckels Diverticulum at eMedicine