Cognitive deficits become worse at first episode psychosis but then return to baseline, and remain fairly stable over the course of the illness.The deficits in cognition are seen to drive the negative psychosocial outcome in schizophrenia, and are claimed to equate to a possible reduction in IQ from the norm of 100 to 70–85. Cognitive deficits may be of neurocognition (nonsocial) or of social cognition. Neurocognition is the ability to receive and remember information, and includes verbal fluency, memory, reasoning, problem solving, speed of processing, and auditory and visual perception. Verbal memory and attention are seen to be the most affected. Verbal memory impairment is associated with a decreased level of semantic processing (relating meaning to words). Another memory impairment is that of episodic memory. An impairment in visual perception that is consistently found in schizophrenia is that of visual backward masking. Visual processing impairments include an inability to perceive complex visual illusions. Social cognition is concerned with the mental operations needed to interpret, and understand the self and others in the social world. This is also an associated impairment, and facial emotion perception is often found to be difficult. Facial perception is critical for ordinary social interaction. Cognitive impairments do not usually respond to antipsychotics, and there are a number of interventions that are used to try to improve them; cognitive remediation therapy is of particular help.Neurological soft signs of clumsiness and loss of fine motor movement are often found in schizophrenia, which may resolve with effective treatment of FEP.
Mediastinal lymphadenopathy or mediastinal adenopathy is an enlargement of the mediastinal lymph nodes. Causes
There are many possible causes of mediastinal lymphadenopathy, including: 

Tuberculosis
Sarcoidosis
Lung cancer/oesophageal cancer
Lymphangitis carcinomatosa
Cystic fibrosis
Histoplasmosis
Acute lymphoblastic leukemia
Coccidioidomycosis
Lymphoma
Whipples disease
Goodpasture syndrome
Hypersensitivity pneumonitisInflammatory response to Silicone (leaked from ruptured implants) which has migrated and collected in mediastinal lymph nodes. Silicone mediastinal lymphadenopathy. See also
Lymphadenopathy
Mediastinum
Mediastinal lymph node
Mediastinal mass
Neoplasia


== References ==