It is also recommended that if the patient also has anemia that ferrous sulfate (200 mg) be administered three times daily at the same time as anthelmintic treatment; this should be continued until hemoglobin values return to normal which could take up to 3 months.Hookworm infection can be treated with local cryotherapy when the hookworm is still in the skin.Albendazole is effective both in the intestinal stage and during the stage the parasite is still migrating under the skin.In case of anemia, iron supplementation can cause relief symptoms of iron-deficiency anemia. However, as red blood cell levels are restored, shortage of other essentials such as folic acid or vitamin B12 may develop, so these might also be supplemented. During the 1910s, common treatments for hookworm included thymol, 2-naphthol, chloroform, gasoline, and eucalyptus oil. By the 1940s, the treatment of choice used tetrachloroethylene, given as 3 to 4 cc in the fasting state, followed by 30 to 45 g of sodium sulfate. Tetrachloroethylene was reported to have a cure rate of 80 percent for Necator infections, but 25 percent in Ancylostoma infections, and often produced mild intoxication in the patient. Reinfection and drug resistance
Other important issues related to the treatment of hookworm are reinfection and drug resistance. It has been shown that reinfection after treatment can be extremely high. Some studies even show that 80% of pretreatment hookworm infection rates can be seen in treated communities within 30–36 months.
If ineffective, splenectomy should be considered.If refractory to both these therapies, other options include rituximab, danazol, cyclosphosphamide, azathioprine, or ciclosporin. High-dose intravenous immune globulin may be effective in controlling hemolysis, but the benefit is short lived (1–4 weeks), and the therapy is very expensive. See also
List of circulatory system conditions

References
External links
Case report of warm-antibody autoimmune hemolytic anemia with typical laboratory findings. Clinical Cases and Images
The wAIHA Warriors is a 501(c)3 support and advocacy group for caregivers and patients of warm autoimmune hemolytic anemia. www.waihawarriors.org