N-acetyl-L-cysteine is soluble in water and alcohol, and practically insoluble in chloroform and ether.It is a white to white with light yellow cast powder, and has a pKa of 9.5 at 30 °C. Dosage forms
Acetylcysteine is available in different dosage forms for different indications:

Solution for inhalation (Assist, Mucomyst, Mucosil) – inhaled for mucolytic therapy
Intravenous injection (Assist, Parvolex, Acetadote) – treatment of paracetamol/acetaminophen overdose
Nebulized as an inhaled vapor, particularly in the treatment of cystic fibrosis and other acute pulmonary conditions
Oral solution – various indications
Effervescent tablets
Ocular solution – for mucolytic therapy
Tablets – sometimes in a sustained release formula sold as a nutritional supplement
CapsulesThe IV injection and inhalation preparations are, in general, prescription only, whereas the oral solution and the effervescent tablets are available over the counter in many countries. Acetylcysteine is available as a health supplement in the United States, typically in capsule form. Society and culture
NAC was first studied as a drug in 1963. Amazon removed NAC for sale in the US in 2021, due to claims by the FDA of it being classified as a drug rather than a supplement. As of 21 April 2022, the FDA released draft guidance on FDAs policy regarding products labeled as dietary supplements that contain N-acetyl-L-cysteine.NAC was studied as a drug and is today used as a medicine. It has also been sold as a dietary supplement within the United States prior to the advent of the Dietary Supplement Health Education Act (DSHEA 1994).
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