NSV is the most common type of vitiligo. Non-segmental
In non-segmental vitiligo (NSV), there is usually some form of symmetry in the location of the patches of depigmentation. New patches also appear over time and can be generalized over large portions of the body or localized to a particular area. Extreme cases of vitiligo, to the extent that little pigmented skin remains, are referred to as vitiligo universalis. NSV can come about at any age (unlike segmental vitiligo, which is far more prevalent in teenage years).Classes of non-segmental vitiligo include the following:

Generalized vitiligo: the most common pattern, wide and randomly distributed areas of depigmentation
Universal vitiligo: depigmentation encompasses most of the body
Focal vitiligo: one or a few scattered macules in one area, most common in children
Acrofacial vitiligo: fingers and periorificial areas
Mucosal vitiligo: depigmentation of only the mucous membranes

Segmental
Segmental vitiligo (SV) differs in appearance, cause, and frequency of associated illnesses. Its treatment is different from that of NSV. It tends to affect areas of skin that are associated with dorsal roots from the spinal cord and is most often unilateral. It is much more stable/static in course and its association with autoimmune diseases appears to be weaker than that of generalized vitiligo. SV does not improve with topical therapies or UV light, however surgical treatments such as cellular grafting can be effective. Differential diagnosis
Chemical leukoderma is a similar condition due to multiple exposures to chemicals. Vitiligo however is a risk factor.
See also
Fleischer ring
Hudson-Stahli line
Limbal ring

References


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