Medical uses
Furosemide is primarily used  for the treatment of edema, but also in some cases of hypertension (where there is also kidney or heart impairment). It is often viewed as a first-line agent in most people with edema caused by congestive heart failure because of its anti-vasoconstrictor and diuretic effects. Compared with furosemide, however, torasemide (aka "torsemide") has been demonstrated to show improvements to heart failure symptoms, possibly lowering the rates of rehospitalisation associated with heart failure, with no difference in risk of death. Torsemide may also be safer than furosemide.Furosemide is also used for liver cirrhosis, kidney impairment, nephrotic syndrome, in adjunct therapy for swelling of the brain or lungs where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration. Kidney disease
In chronic kidney diseases with hypoalbuminemia, furosemide is used along with albumin to increase diuresis. It is also used along with albumin in nephrotic syndrome to reduce edema. Other information
Furosemide is mainly excreted by tubular secretion in the kidney. In kidney impairment, clearance is reduced, increasing the risk of adverse effects. Lower initial doses are recommended in older patients (to minimize side-effects) and high doses may be needed in kidney failure. It can also cause kidney damage; this is mainly by loss of excessive fluid (i.e., dehydration), and is usually reversible.Furosemide acts within 1 hour of oral administration (after IV injection, the peak effect is within 30 minutes).
Freckles (spots of melanin on the skin, and distinct from moles) are known to be influenced by sunlight.Studies have found that sunburns and too much time in the sun can increase the risk factors for melanoma. This is in addition to those who have dysplastic nevi being at higher risk of this cancer (the uncertainty is in regard to acquiring benign moles). To prevent and reduce the risk of melanoma caused by UV radiation, the American Academy of Dermatology and the National Cancer Institute recommends staying out of the sun between 10 a.m. and 4 p.m. standard time (or whenever ones shadow is shorter than ones height). The National Cancer Institute also recommends wearing long sleeves and trousers, hats with a wide brim, sunscreens, and sunglasses that have UV-deflecting lenses. Diagnosis
Clinical diagnosis can be made with the naked eye using the ABCD guideline or by using dermatoscopy. An online-screening test is also available to help screen out benign moles. Classification
Melanocytic nevi can mainly be classified by depth, being congenital versus acquired, and/or specific dermatoscopy or histopathology patterns:

Depth

Congenital versus acquired
Congenital nevus: Small to large nevus present at or near time of birth. Small ones have low potential for forming melanomas, however the risk increases with size, as in the giant pigmented nevus. Acquired nevus:  Any melanocytic nevus that is not a congenital nevus or not present at birth or near birth.Specific dermatoscopy or histopathology patterns
Recurrence
Recurrent nevus:  Any incompletely removed nevus with residual melanocytes left in the surgical wound.