Researchers at the Abramson Cancer Center of the University of Pennsylvania School of Medicine reported preliminary success in the use of gene therapy, through genetically modified T cells, to treat CLL. The findings, which were published in August 2011, were based on data from three patients who had modified T cells injected into their blood. The T cells had been modified to express genes that would allow the cells to proliferate in the body and destroy B cells including those causing the leukemia. Two patients went into remission, while the presence of leukemia in the third patient reduced by 70%.One of the patients had been diagnosed with CLL for 13 years, and his treatment was failing before he participated in the clinical trial. One week after the T cells were injected, the leukemia cells in his blood had disappeared. The T cells were still found in the bloodstream of the patients six months after the procedure, meaning they would be able to fight the disease should leukemia cells return. This was the first time scientists "have used gene therapy to successfully destroy cancer tumors in patients with advanced disease".Research is also investigating therapies targeting B cell receptor signalling. Syk inhibitors fostamatinib and entospletinib are currently in trials. The trial of a combination of ibrutinib and venetoclax had encouraging results in a small number of people.People with CLL undergoing immunotherapy with chimeric antigen receptor T cells have been found to have a high response rate.
Late-night TV entertainer David Letterman and former astronaut Story Musgrave were both stalked by Margaret Mary Ray, who had erotomania.Michael David Barrett allegedly had erotomania, stalking ESPN correspondent Erin Andrews across the country, trying to see her and taking lewd videos.Many cases of obsession or stalking can be linked to erotomania but do not always necessarily go hand in hand. In media
Nurse Betty (2000)
A main character in Orange Is the New Black, Lorna Morello, exhibits erotomanic behavior towards a man she has delusions of being engaged to. He Loves Me... He Loves Me Not (2002)
A 2011 episode (Series 5, Episode 3) of the British TV series Lewis features a character with erotomania, referred to in the show as de Clérambaults syndrome. Enduring Love (1997)
Criminal Minds Season 1, Episode 5: Broken Mirror. Doc Martin Season 6, Episode 3: The Tameness of a Wolf

See also
Further reading
Remington GJ, Jeffries JJ (1994). "Erotomanic delusions and electroconvulsive therapy: a case series". J Clin Psychiatry. 55 (7): 306–8. PMID 8071292. Anderson CA, Camp J, Filley CM (1998). "Erotomania after aneurysmal subarachnoid hemorrhage: case report and literature review". J Neuropsychiatry Clin Neurosci. 10 (3): 330–7. doi:10.1176/jnp.10.3.330. PMID 9706541. {{cite journal}}:  CS1 maint: multiple names: authors list (link)
Frank Bruni, Behind the Jokes, a Life Of Pain and Delusion; For Letterman Stalker, Mental Illness Was Family Curse and Scarring Legacy, New York Times, November 22, 1998
Foster, David & Levinson, Arlene.