Virginia Satir expanded on the concept of how individuals behave and communicate in groups by describing several family roles that can serve to stabilize expected characteristic behavior patterns in a family. For instance, if one child is considered to be a "rebel child", a sibling may take on the role of the "good child" to alleviate some of the stress in the family. This concept of role reciprocity is helpful in understanding family dynamics because the complementary nature of roles makes behaviors more resistant to change. It is good to understand that most depression in children and adolescents begin right in the home. Parents are advised to treat their children properly and learn to fully understand their child/children, and also give them adequate attention, love, care and quick response to their useful needs. Parents and Guardians should detest ignoring their children or wards and give them attention because neglect can lead to shame, loss of self-confidence, frustration and finally depression. Antidepressants
As of 2021, the FDA has approved the selective serotonin reuptake inhibitors (SSRIs) fluoxetine and escitalopram for the treatment of depression in adolescents but other SSRIS or serotonin norepinephrine reuptake inhibitors (SNRIs) are often used off label for treatment. Clinicians usually recommend one of these SSRIs as a first line treatment for depression in adolescence. These drugs act on the serotonin system that affects mood, arousal, anxiety, impulses, and aggression. SSRIs also appear to indirectly influence other neurotransmitter systems, including those involving norepinephrine and dopamine.
Urinary preparations
Purified urinary FSH (75 IU FSH and ≤ 2 IU of LH)Generic
urofollitropin for injection, purified.Brands
Bravelle, U.S., (≤ 2 IU LH)
Metrodin, U.S. and Canada, (≤ 1 IU LH)
Fertinorm Hp, (Canada)Highly purified urinary FSH (75 IU FSH and ≤ 0.1 IU LH/1000 IU FSH)Generic
urofollitropin for injection, (highly) purified.Dosage
typically 75 - 300, but as high as 600 IU / dayBrands
Fertinex (≤ 0.1 IU LH/1000 IU FSH)

Recombinant preparations
Follitropin alfaGeneric
Follitropin alfa injectionBrandsGonal-f
Cinnal-f
Fertilex
Ovaleap
BemfolaFollitropin betaGeneric
follitropin beta injectionBrands
Follistim AQ
PuregonFollitropin deltaGeneric
follitropin delta injectionBrands
RekovelleThe package insert for Gonal-f states that based on physio-chemical tests and bioassays that follitropin beta and follitropin alfa are indistinguishable. Two studies showed no difference. However, a more recent study showed there may be a slight clinical difference, with the alfa form tending towards a higher pregnancy rate and the beta form tending towards a lower pregnancy rate, but with significantly higher estradiol (E2) levels.The package insert for Puregon states that structural analysis shows that the amino acid sequence of follitropin beta is identical to that of natural human follicle stimulating hormone (hFSH). Further, the ogliosaccharide side chains are very similar, but not completely identical to that of natural hFSH. However, these small differences do not affect the bioactivity compared to natural hFSH. Gonal-f was approved for medical use in the European Union in October 1995.Puregon was approved for medical use in the European Union in February 1996.Rekovelle was approved for medical use in the European Union in December 2016. Biosimilars
Ovaleap was approved for medical use in the European Union in September 2013.