Mutations in the SLC26A2 gene alter the structure of developing cartilage, preventing bones from forming properly and resulting in the skeletal problems characteristic of diastrophic dysplasia. This condition is an autosomal recessive disorder, meaning that the defective gene is located on an autosome, and both parents must carry one copy of the defective gene in order to have a child born with the disorder. The parents of a child with an autosomal recessive disorder are usually not affected by the disorder. Prevalence
Diastrophic dysplasia affects about one in 500,000 births, however; in Finland, this disorder is more common, with about in 1 in 33,000 births being affected by the disorder. See also
Achondrogenesis type 1B

References
This article incorporates some public domain text from The U.S. National Library of Medicine

External links

GeneReviews/NCBI/NIH/UW entry on Diastrophic Dysplasia
References
External links
An academic presentation on gingival recession
Highly informative overview article from the NYTimes.