Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women. It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women. The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others). A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications. EE/DRSP is marketed widely throughout the world.In 2019, it was the 148th most commonly prescribed medication in the United States, with more than 4 million prescriptions. See also
Ethinylestradiol/drospirenone/levomefolic acid
Ethinylestradiol/drospirenone/prasterone
Estradiol/drospirenone
List of combined sex-hormonal preparations § Estrogens and progestogens

References
External links
"Drospirenone mixture with estradiol". Drug Information Portal. U.S. National Library of Medicine.
Furthermore,  cigarette smoke was discovered to increase COX-2 and PGE2 expression in fibroblasts, which could indicate the role of cigarette smoke in Reinkes edema.While smoking is a clear risk factor to Reinkes edema, other risk factors are being identified to explain Reinkes edema in nonsmokers. Research has suggested the role of bacterial colonies in non-neoplastic lesions such as Reinkes edema. Using pyrosequencing, strains of S. pseudopneumoniae were found as the dominant bacterial strain across most non-neoplastic lesions. Of all the sequences analyzed, streptococcus represented 72.9% of bacteria found within these lesions. While smoking, gastric reflux, and vocal abuse have been more widely agreed upon in literature as risk factors for Reinkes edema, the altered bacterial cultures could be developed as a diagnostic tool in the future.The majority of the research within the last ten years focuses on improving surgery for Reinkes edema. Due to the importance of the Reinkes space in speech, it is important that minimally invasive techniques be perfected that minimize the risk of complications. The CO2 laser has been successfully incorporated into the surgical technique, however, there are several other lasers being investigated for use in Reinkes edema. These include photoangiolytic lasers and potassium titanyl phosphate lasers. See also
List of voice disorders
Histology of the Vocal Folds

References
Notes"Benign Vocal Lesions - Nodules, Polyps, Cysts". The Center for Voice at Northwestern University. Archived from the original on August 17, 2007. Retrieved July 24, 2007. External links

"Illustration of Reinkes Edema". The Center for Voice at Northwestern University. Archived from the original on August 17, 2007.