The Ramones, an influential early US punk band, referred to inhalant use in several of their songs. The song "Now I Wanna Sniff Some Glue" describes adolescent boredom, and the song "Carbona not Glue" states, "My brain is stuck from shooting glue." An influential punk fanzine about the subculture and music took its name (Sniffin Glue) from the Ramones song. The 1980s punk band The Dead Milkmen wrote a song, "Life is Shit" from their album Beelzebubba, about two friends hallucinating after sniffing glue. Punk-band-turned-hip-hop group the Beastie Boys penned a song "Hold it Now – Hit It", which includes the line "cause Im beer drinkin, breath stinkin, sniffing glue." Their song "Shake Your Rump" includes the lines, "Should I have another sip no skip it/In the back of the ride and bust with the whippits". Pop punk band Sum 41 wrote a song, "Fat Lip", which refers to a character who does not "make sense from all the gas you be huffing..." The song Lança-perfume, written and performed by Brazilian pop star Rita Lee, became a national hit in 1980. The song is about chloroethane and its widespread recreational sale and use during the rise of Brazils carnivals. Inhalants are referred to by bands from other genres, including several grunge bands—an early 1990s genre that was influenced by punk rock.
Although the AWOL machine is marketed as having no downsides, such as the lack of calories or hangovers, Amanda Shaffer of Slate describes these claims as "dubious at best". Although inhaled alcohol does reduce the caloric content, the savings are minimal. After expressed safety and health concerns, sale or use of AWOL machines was banned in a number of American states.The effects of solvent intoxication can vary widely depending on the dose and what type of solvent or gas is inhaled. A person who has inhaled a small amount of rubber cement or paint thinner vapor may be impaired in a manner resembling alcohol inebriation. A person who has inhaled a larger quantity of solvents or gases, or a stronger chemical, may experience stronger effects such as distortion in perceptions of time and space, hallucinations, and emotional disturbances. The effects of inhalant use are also modified by the combined use of inhalants and alcohol or other drugs. In the short term, many users experience headaches, nausea and vomiting, slurred speech, loss of motor coordination, and wheezing. A characteristic "glue sniffers rash" around the nose and mouth is sometimes seen after prolonged use. An odor of paint or solvents on clothes, skin, and breath is sometimes a sign of inhalant abuse, and paint or solvent residues can sometimes emerge in sweat.According to NIH, even a single session of inhalant use "can disrupt heart rhythms and lower oxygen levels", which can lead to death. "Regular abuse can result in serious harm to the brain, heart, kidneys, and liver."