This may cause a sensation of mass or fullness in the lower abdomen, pain in the stomach and back, along with problems with urinating and bowel movements. Chemical exposure of the vaginal epithelia may lead to tissue damage (up to and including necrosis) and swelling (edema). The edematous blockage of the vagina results in identical symptomatology as the imperforate hymen. Cervical atresia is a relatively rare Mullerian duct anomaly of the female reproductive tract. It is associated with acute or chronic pain in the abdomen or pelvic pain along with other reproductive problems. A significant share of the women with cervical atresia have it since birth, that is, congenital cervical atresia. However, Cervical Atresia is distinct from other Mullerian duct anomalies. Vaginal atresia: Vaginal atresia is another congenital defect which results in the uterovaginal outflow tract obstruction. it occurs when the caudal portion of the vagina fails to form and is rather replaced with fibrous tissues only. Vaginal atresia has three basic categories of anomalies- vaginal agenesis, ambiguous genitalia, and imperforate anus and urogenital sinus variants. The different features associated with an ambiguous genitalia which might eventually lead to a blockage of menstrual blood flow are:  i) Rugal folds over the labia ii) Mass in an apparent labium iii) Excess clitoral tissue. Due to these anomalies, there are chances that the menstrual blood would not be able to flow out of the vagina, eventually leading to hematocolpos.
Transverse vaginal septum: A transverse vaginal septum is another medical condition whereby an extra horizontal wall of tissue that has formed during embryological development creates a blockage in the vagina. Transverse vaginal septa are relatively rare anomalies, occurring in about 1 in 70,000 girls. The diagnosis can be made at various ages, from neonates presenting with hydrocolpos to young women presenting with primary amenorrhea and pelvic pain due to the development of hematocolpos. Often, women might have a normal hymeneal opening but this wall of tissue might be blocking the access to the vaginal canal. A small opening in the septum called the fenestration allows the menstrual blood to flow out of the vagina. However, it takes longer than the usual menstrual cycle. For the women who do not have a fenestration, blood will pool in the upper vagina and this would lead to serious abdominal pain. This also results in infertility. Treatment
As the causes for Hematocolpos are diverse, there are different surgical treatments which needs to be undertaken to cure it. Surgical interventions for congenital cervical atresia range from complete hysterectomy with canalization to conservative options, such as uterine cavity catheterization.For the women who have an imperforate hymen, a minor surgery is required incising the extra hymen membrane. It is generally treated surgically, with a hymenotomy or other surgery to remove any tissue that blocks the menstrual flow.