Failure to respond to NSAIDs within one week (indicated by persistence of fever, worsening of condition, new pericardial effusion, or continuing chest pain) likely indicates that a cause other than viral or idiopathic is in process.Colchicine, which has been essential to treat recurrent pericarditis, has been supported for routine use in acute pericarditis by recent prospective studies. Colchicine can be given 0.6 mg twice a day (0.6 mg daily for patients <70 kg) for 3 months following an acute attack. It should be considered in all patients with acute pericarditis, preferably in combination with a short-course of NSAIDs. For patients with a first episode of acute idiopathic or viral pericarditis, they should be treated with an NSAID plus colchicine 1–2 mg on first day followed by 0.5 daily or twice daily for three months. It should be avoided or used with caution in patients with severe chronic kidney disease, hepatobiliary dysfunction, blood dyscrasias, and gastrointestinal motility disorders.Corticosteroids are usually used in those cases that are clearly refractory to NSAIDs and colchicine and a specific cause has not been found. Systemic corticosteroids are usually reserved for those with autoimmune disease. Prognosis
One of the most feared complications of acute pericarditis is cardiac tamponade. Cardiac tamponade is accumulation of enough fluid in the pericardial space --- pericardial effusion --- to cause serious obstruction to the inflow of blood to the heart. Signs of cardiac tamponade include distended neck veins, muffled heart sounds when listening with a stethoscope, and low blood pressure (together known as Becks triad).
In adults, evidence of the effectiveness of various non-surgical interventions is less clear.Both positive fusional vergence (PFV) and negative fusional vergence (NFV) can be trained, and vergence training should normally include both. Surgical correction options are also available, but the decision to proceed with surgery should be made with caution as convergence insufficiency generally does not improve with surgery. Bilateral medial rectus resection is the preferred type of surgery. However, the patient should be warned about the possibility of uncrossed diplopia at distance fixation after surgery. This typically resolves within one to three months postoperatively. The exophoria at near often recurs after several years, although most patients remain asymptomatic. Reading difficulty
In some cases, convergence Insufficiency can be the underlying cause of difficulty learning to read. As a result of the eyes not converging on the same point for sustained periods of time when reading, words can appear blurry or double because the brain is receiving two different images. Convergence insufficiency is not a learning disability. However, some children with the condition who are struggling to learn to read can be confused for having dyslexia due to difficulty learning to read. Children struggling with symptoms such as letters appearing blurry or double and experience tiredness or headaches when reading should consult an optometrist. Prevalence
Among fifth and sixth grade children convergence insufficiency is 13%. In studies that used standardized definitions of convergence insufficiency, investigators have reported a prevalence of 4.2% to 6% in school and clinic settings.