To be initiated under a guru, one must have had no caffeine, alcohol, nicotine or other drugs, for at least a year.Caffeinated beverages are widely consumed by Muslims today. In the 16th century, some Muslim authorities made unsuccessful attempts to ban them as forbidden "intoxicating beverages" under Islamic dietary laws. Other organisms
Recently discovered bacteria Pseudomonas putida CBB5 can live on pure caffeine and can cleave caffeine into carbon dioxide and ammonia.Caffeine is toxic to birds and to dogs and cats, and has a pronounced adverse effect on mollusks, various insects, and spiders. This is at least partly due to a poor ability to metabolize the compound, causing higher levels for a given dose per unit weight. Caffeine has also been found to enhance the reward memory of honey bees. Research
Caffeine has been used to double chromosomes in haploid wheat. See also
Theobromine
Theophylline
Methylliberine
Adderall
Amphetamine
Cocaine
Nootropic
Wakefulness-promoting agent

References
Notes
Citations

Bibliography
Bersten I (1999). Coffee, Sex & Health: A history of anti-coffee crusaders and sexual hysteria. Sydney: Helian Books. ISBN 978-0-9577581-0-0. Carpenter M (2015). Caffeinated: How Our Daily Habit Helps, Hurts, and Hooks Us. Plume. ISBN 978-0142181805. Pendergrast M (2001) [1999]. Uncommon Grounds: The History of Coffee and How It Transformed Our World. London: Texere. ISBN 978-1-58799-088-5. Pollan M (2021). This Is Your Mind on Plants. Penguin Press. ISBN 9780593296905. External links

GMD MS Spectrum
Caffeine: ChemSub Online
Caffeine at The Periodic Table of Videos (University of Nottingham)
The McMredie-McBride hypothesis explains that the limbs of the infants become malformed as a result of the thalidomide harming the neural tissue—simply because the neural tissue has such a large impact on formation and development of the limbs. Causes
Thalidomide
Thalidomide was released onto the market in 1958 in West Germany under the name Contergan. Primarily prescribed as a sedative or hypnotic, thalidomide also claimed to cure "anxiety, insomnia, gastritis, and tension". Afterwards it was used against nausea and to alleviate morning sickness in pregnant women. Thalidomide became an over-the-counter drug in Germany around 1960, i.e. it could be bought without a prescription. Shortly after the drug was sold, in Germany between 5,000 and 7,000 infants were born with phocomelia. Only 40% of these children survived.Research also proves that although phocomelia did exist through the 1940s and 1950s cases of severe phocomelia multiplied in the 1960s when thalidomide was released in Germany; the direct cause was traced to thalidomide. The statistic was given that "50 percent of the mothers with deformed children had taken thalidomide during the first trimester of pregnancy." Throughout Europe, Australia and the United States 10,000 cases were reported of infants with phocomelia; only 50% of the 10,000 survived. Thalidomide became effectively linked to death or severe disabilities among babies. Those subjected to thalidomide while in the womb experienced limb deficiencies in that the long limbs either were not developed or presented themselves as stumps. Other effects included deformed eyes, hearts, alimentary and urinary tracts, blindness and deafness.