In those with Tourette syndrome and ADHD, donepezil may reduce tics while it had no effect on ADHDs symptoms. Pervasive developmental disorder
Donepezil along with other cholinesterase inhibitors is suggested as having potential for trouble behaviors, irritability, hyperactivity, and difficulty in social communication which are typically seen in those with pervasive developmental disorder, pervasive developmental disorder not otherwise specified, or autism spectrum disorder. References
Further reading
Brenner, George D.; George M. Brenner (2000). Pharmacology. Philadelphia: W. B. Saunders. ISBN 978-0-7216-7757-6. Louise Welbanks (2000). Compendium of Pharmaceuticals and Specialities (25th ed.). Canadian Pharmacists Association. ISBN 978-0-919115-76-7. External links
"Donepezil". Drug Information Portal. U.S. National Library of Medicine. "Donepezil hydrochloride". Drug Information Portal. U.S. National Library of Medicine.
Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. It can be taken by mouth, injected into a vein, used topically as a skin cream, or as eye drops.Side effects with short-term use include nausea and feeling tired. More severe side effects include psychiatric problems, which may occur in about 5% of people. Common side effects with long term use include bone loss, weakness, yeast infections, and easy bruising. While short-term use in the later part of pregnancy is safe, long-term use or use in early pregnancy is occasionally associated with harm to the baby. It is a glucocorticoid made from hydrocortisone (cortisol).Prednisolone was discovered and approved for medical use in 1955. It is on the World Health Organizations List of Essential Medicines. It is available as a generic medication. In 2019, it was the 139th most commonly prescribed medication in the United States, with more than 4 million prescriptions.