This marked the end of the Great Depression.How the Other Half Lives and Jack Londons The People of the Abyss (1903) discussed homelessness and raised public awareness, which caused some changes in building codes and some social conditions. In England, dormitory housing called "spikes" was provided by local boroughs. By the 1930s in England, there were 30,000 people living in these facilities. In 1933, George Orwell wrote about poverty in London and Paris, in his book Down and Out in Paris and London. In general, in most countries, many towns and cities had an area that contained the poor, transients, and afflicted, such as a "skid row". In New York City, for example, there was an area known as "the Bowery", traditionally, where people with an alcohol use disorder were to be found sleeping on the streets, bottle in hand. In the 1960s in the UK, nature and growing problem of homelessness changed in England as public concern grew. The number of people living "rough" in the streets had increased dramatically. However, beginning with the Conservative administrations Rough Sleeper Initiative, the number of people sleeping rough in London fell dramatically.
Chompret criteria
A 2015 revision of the traditional Chompret criteria for screening has been proposed - a proband who has:
A tumor belonging to LFS tumor spectrum (e.g., premenopausal breast cancer, soft tissue sarcoma, osteosarcoma, CNS tumor, adrenocortical carcinoma) before age 46 years, and at least one first- or second-degree relative with LFS tumor (except breast cancer if the proband has breast cancer) before age 56 years or with multiple tumors at any age
Multiple tumors (except multiple breast tumors), two of which belong to LFS spectrum with the initial cancer occurring before the age of 46 years
An adrenocortical carcinoma, choroid plexus tumor, or rhabdomyosarcoma of embryonal anaplastic subtype, at any age of onset, irrespective of family history
Breast cancer before age 31

Recommendations
Recommendations for individuals from families affected by the syndrome include:
Avoidance of radiation therapy to reduce risk of secondary radiation-induced malignancies
Children and adults undergo comprehensive annual physical examination
Women undergo age-specific breast cancer monitoring beginning at age 25 years
All patients consult a physician promptly for evaluation of lingering symptoms and illnesses

Suggestions
Adults should undergo routine screening for colorectal cancer beginning no later than age 25 years. Individuals should undergo organ-targeted surveillance based on the pattern of cancer observed in their families. Prophylactic mastectomy to reduce the risk of breast cancer is an option. Epidemiology
Li–Fraumeni syndrome (LFS) is rare; as of 2011, cases had been reported in more than 500 families. The syndrome was discovered using an epidemiological approach.