However, it remains insufficient evidences related to the efficacy of pharmacological treatment in PLMD, and its use has been based on the dopaminergic medication effect on RLS. Therefore, a careful clinical monitoring with any pharmacological use in PLMD is recommended. Epidemiology
PLMD is estimated to occur in approximately 4% of adults (aged 15–100), but is more common in the elderly, especially females, with up to 11% experiencing symptoms. PLMD appears to be related to restless legs syndrome (RLS) - a study of 133 people found that 80% of those with RLS also had PLMS. However the opposite is not true: many people who have PLMS do not also have restless legs syndrome.PLMD is an uncommon childhood disorder. Based on adult criteria and PSG analysis, studies showed prevalence of isolated PLMD in children population with no other comorbidity about 1.2 to 1.5%. There was also evidence for 5.6 to 7.7% of children with PLMI > 5/hr. Periodic limb movements during sleep are associated with a lower quality of life in children with monosymptomatic nocturnal enuresis

See also
Hypnic jerk
Restless legs syndrome

References


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Trichofolliculoma is a cutaneous condition characterized by a benign, highly structured tumor of the pilosebaceous unit. : 671

See also
Multiple familial trichoepithelioma
Pilomatricoma
Skin lesion
List of cutaneous conditions

References


== External links ==