Most deaths following remission are from other causes, such as second malignancies, which in one study occurred in 8% of patients. In this study, second malignancies accounted for 41% of deaths, and heart disease, 29%. Survival rates were 88% at 6.3 years and 82% at 7.9 years.In another study, 10-year survival rate was estimated to be approximately 77%. Epidemiology
Acute promyelocytic leukemia represents 10–12% of AML cases. The median age is approximately 30–40 years, which is considerably younger than the other subtypes of AML (70 years), however in elderly population APL has peculiar characteristics. Incidence is higher among individuals of Latin American or South European origin. It can also occur as a secondary malignancy in those that receive treatment with topoisomerase II inhibitors (such as the anthracyclines and etoposide) due to the carcinogenic effects of these agents, with patients with breast cancer representing the majority of such patients. Around 40% of patients with APL also have a chromosomal abnormality such as trisomy 8 or isochromosome 17 which do not appear to impact on long-term outcomes. References
External links

Sanz, Miguel A.; Grimwade, David; Tallman, Martin S.; Lowenberg, Bob; Fenaux, Pierre; Estey, Elihu H.; Naoe, Tomoki; Lengfelder, Eva; Büchner, Thomas; Döhner, Hartmut; Burnett, Alan K.; Lo-Coco, Francesco (2009). "Management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the European Leukemia Net". Blood. 113 (9): 1875–1891. doi:10.1182/blood-2008-04-150250. hdl:1765/18239. PMID 18812465. PDQ Adult Treatment Editorial Board (2002–2020). "Adult Acute Myeloid Leukemia Treatment (PDQ®): Patient Version". Adult Acute Myeloid Leukemia Treatment (PDQ®). National Cancer Institute (US). PMID 26389377.
Prurigo is an itchy eruption of the skin.Specific types include:

Prurigo nodularis
Actinic prurigo
Besniers prurigo (a specific type of atopic dermatitis). References


== External links ==