Sensory processing therapy
This therapy retains all of the above-mentioned four principles and adds:
Intensity (person attends therapy daily for a prolonged period of time)
Developmental approach (therapist adapts to the developmental age of the person, against actual age)
Test-retest systematic evaluation (all clients are evaluated before and after)
Process driven vs. activity driven (therapist focuses on the "just right" emotional connection and the process that reinforces the relationship)
Parent education (parent education sessions are scheduled into the therapy process)
"Joie de vivre" (happiness of life is therapys main goal, attained through social participation, self-regulation, and self-esteem)
Combination of best practice interventions (is often accompanied by integrated listening system therapy, floor time, and electronic media such as Xbox Kinect, Nintendo Wii, Makoto II machine training and others)While occupational therapists using a sensory integration frame of reference work on increasing a childs ability to adequately process sensory input, other OTs may focus on environmental accommodations that parents and school staff can use to enhance the childs function at home, school, and in the community. These may include selecting soft, tag-free clothing, avoiding fluorescent lighting, and providing ear plugs for "emergency" use (such as for fire drills). Evaluation of treatment effectiveness
A 2019 review found sensory integration therapy to be effective for autism spectrum disorder.
Although hydroxyzine has a long elimination half-life and produces antihistamine for as long as 24 hours, the CNS effects of hydroxyzine and other antihistamines with long half-lives seem to diminish after 8 hours.Administration in geriatrics differs from the administration of hydroxyzine in younger patients; according to the FDA, there have not been significant studies made (2004), which include population groups over 65, which provide a distinction between elderly aged patients and other younger groups. Hydroxyzine should be administered carefully in the elderly with consideration given to possible reduced elimination. Chemistry
Hydroxyzine is a member of the diphenylmethylpiperazine class of antihistamines. Hydroxyzine is supplied mainly as a dihydrochloride salt (hydroxyzine hydrochloride) but also to a lesser extent as an embonate salt (hydroxyzine pamoate). The molecular weights of hydroxyzine, hydroxyzine dihydrochloride, and hydroxyzine pamoate are 374.9 g/mol, 447.8 g/mol, and 763.3 g/mol, respectively. Due to their differences in molecular weight, 1 mg hydroxyzine dihydrochloride is equivalent to about 1.7 mg hydroxyzine pamoate. Analogues
Analogues of hydroxyzine include buclizine, cetirizine, cinnarizine, cyclizine, etodroxizine, meclizine, and pipoxizine among others. Synthesis
Hydroxyzine is synthesized by the alkylation of 1-(4-chlorobenzhydryl)piperazine with 2-(2-chloroethoxy)ethanol:

Society and culture
Brand names
Hydroxyzine preparations require a doctors prescription. The drug is available in two formulations, the pamoate (anxiolytic) and the dihydrochloride or hydrochloride salts (antihistamine). Vistaril, Equipose, Masmoran, and Paxistil are preparations of the pamoate salt, while Atarax, Alamon, Aterax, Durrax, Tran-Q, Orgatrax, Quiess, and Tranquizine are of the hydrochloride salt. References
External links
"Hydroxyzine". Drug Information Portal. U.S. National Library of Medicine.