Society and culture
As of July 2017 it was marketed under many brand names worldwide: Allersoothe, Antiallersin, Anvomin, Atosil, Avomine, Closin N, Codopalm, Diphergan, Farganesse, Fenazil, Fenergan, Fenezal, Frinova, Hiberna, Histabil, Histaloc, Histantil, Histazin, Histazine, Histerzin, Lenazine, Lergigan, Nufapreg, Otosil, Pamergan, Pharmaniaga, Phenadoz, Phenerex, Phenergan, Phénergan, Pipolphen, Polfergan, Proazamine, Progene, Prohist, Promet, Prometal, Prometazin, Prometazina, Promethazin, Prométhazine, Promethazinum, Promethegan, Promezin, Proneurin, Prothazin, Prothiazine, Prozin, Pyrethia, Quitazine, Reactifargan, Receptozine, Romergan, Sominex, Sylomet, Xepagan, Zinmet, and Zoralix. It is also marketed in many combination drug formulations:

with carbocisteine as Actithiol Antihistaminico, Mucoease, Mucoprom, Mucotal Prometazine, and Rhinathiol;
with paracetamol (acetaminophen) as Algotropyl, Calmkid, Fevril, Phen Plus, and Velpro-P;
with paracetamol  and dextromethorphan as Choligrip na noc, Coldrex Nočná Liečba, Fedril Night Cold and Flu, Night Nurse, and Tachinotte;
with paracetamol, phenylephrine, and salicylamide as Flukit;
with dextromethorphan as Axcel Dextrozine and Hosedyl DM;
with dextromethorphan and ephedrine as Methorsedyl;
with dextromethorphan and pseudoephedrine as Sedilix-DM;
with dextromethorphan and phenylephedrine as Sedilix-RX;
with pholcodine as Codo-Q Junior and Tixylix;
with pholcodine and ephedrine as Phensedyl Dry Cough Linctus;
with pholcodine and phenylephedrine as Russedyl Compound Linctus;
with pholcodine and phenylpropanolamine as Triple P;
with codeine as Kefei and Procodin;
with codeine and ephedrine as Dhasedyl, Fendyl, and P.E.C. ;
with ephedrine  and dextromethorphan as Dhasedyl DM;
with glutamic acid as Psico-Soma, and Psicosoma;
with noscapine as Tussisedal; and
with chlorpromazine  and phenobarbital as Vegetamin. Recreational use
The recreational drug lean, also known as purple drank among other names, often contains a combination of promethazine with codeine-containing cold medication. Product liability lawsuit
In 2009, the US Supreme Court ruled on a product liability case involving promethazine.
Despite a scarcity of controlled studies on alternative medicine and IC/BPS, "rather good results have been obtained" when acupuncture is combined with other treatments.Biofeedback, a relaxation technique aimed at helping people control functions of the autonomic nervous system, has shown some benefit in controlling pain associated with IC/BPS as part of a multimodal approach that may also include medication or hydrodistention of the bladder. Prognosis
IC/BPS has a profound impact on quality of life. A 2007 Finnish epidemiologic study showed that two-thirds of women at moderate to high risk of having interstitial cystitis reported impairment in their quality of life and 35% of people with IC reported an impact on their sexual life. A 2012 survey showed that among a group of adult women with symptoms of interstitial cystitis, 11% reported suicidal thoughts in the past two weeks. Other research has shown that the impact of IC/BPS on quality of life is severe and may be comparable to the quality of life experienced in end-stage kidney disease or rheumatoid arthritis.International recognition of interstitial cystitis has grown and international urology conferences to address the heterogeneity in diagnostic criteria have recently been held. IC/PBS is now recognized with an official disability code in the United States of America. Epidemiology
IC/BPS affects men and women of all cultures, socioeconomic backgrounds, and ages. Although the disease was previously believed to be a condition of menopausal women, growing numbers of men and women are being diagnosed in their twenties and younger. IC/BPS is not a rare condition.