Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections, hydatid disease, and giardia, among others. It is taken by mouth.Mebendazole is usually well tolerated. Common side effects include headache, vomiting, and ringing in the ears. If used at large doses it may cause bone marrow suppression. It is unclear if it is safe in pregnancy. Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type.Mebendazole came into use in 1971, after it was developed by Janssen Pharmaceutica in Belgium. It is on the World Health Organizations List of Essential Medicines. Mebendazole is available as a generic medication. Medical use
Mebendazole is a highly effective, broad-spectrum antihelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm (pinworm), and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract. Other drugs are used to treat worm infections outside the digestive tract, as mebendazole is poorly absorbed into the bloodstream. Mebendazole is used alone in those with mild to moderate infestations. It kills parasites relatively slowly, and in those with very heavy infestations, it can cause some parasites to migrate out of the digestive system, leading to appendicitis, bile duct problems, or intestinal perforation. To avoid this, heavily infested patients may be treated with piperazine, either before or instead of mebendazole. Piperazine paralyses the parasites, causing them to pass in the feces.
Alexis Littre (17 July 1654 – 3 February 1726) was a French physician and anatomist born in Cordes (currently Cordes-Tolosannes in the department of Tarn-et-Garonne). Biography
Littre studied medicine in Montpellier and Paris, receiving his doctorate in 1691. In 1699 he became a member of the Académie des Sciences. In Paris, he taught anatomy and was the author of numerous medical publications. He was the first to give a description of a hernial protrusion of an intestinal diverticulum. This condition is now referred to as "Littres hernia".He also described the mucous urethral glands of the male urethra. These structures were to become known as "Littres glands", and their inflammation is sometimes called "littreitis".In his 1710 treatise Diverses observations anatomiques, Littre was the first to suggest the possibility of performing a lumbar colostomy for an obstruction of the colon.Jean Louis Petit was one of his students. So was Jacques-Bénigne Winslow in 1707. He died in Paris. References
Alexis de Littre @ Who Named It

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External links
Online articles by Littré 10 articles (2012-05-15) on the site of the Académie des sciences. Cotlar, Alvin M. (January 2002). "Historical landmarks in operations on the colon—surgeons courageous". Current Surgery. Elsevier. 59 (1): 91–95. doi:10.1016/s0149-7944(01)00606-7. ISSN 0149-7944. PMID 16093113. Bernard Le Bovier de Fontenelle, Éloge de Monsieur Littré, p. 129, at Google Books, 1754, p. 129 (Eulogy)