Toxicology also manifests in the autonomic nervous system, primarily at the neuromuscular junction, resulting in ataxia and extrapyramidal side effects and the feeling of heaviness in the legs, and at sympathetic post-ganglionic junctions, causing urinary retention, pupil dilation, tachycardia, irregular urination, and dry red skin caused by decreased exocrine gland secretions, and mucous membranes. Considerable overdosage can lead to myocardial infarction (heart attack), serious ventricular arrhythmias, coma, and death. Such a side effect profile is thought to give ethanolamine-class antihistamines a relatively low abuse liability. An antidote that can be used for dimenhydrinate poisoning is physostigmine. Brand names
Dimenhydrinate is marketed under many brand names: in the US, Mexico, Turkey and Serbia as Dramamine; in Ukraine as Driminate; in Canada, Costa Rica, and India as Gravol; in Iceland as Gravamin; in Russia and Croatia as Dramina; in South Africa and Germany as Vomex; in Australia and Austria as Vertirosan; in Brazil as Dramin; in Colombia as Mareol; in Ecuador as Anautin; in Hungary as Daedalon; in Indonesia as Antimo; in Italy as Xamamina or Valontan; in Peru as Gravicoll; in Poland and Slovakia as Aviomarin; in Portugal as Viabom, Vomidrine, and Enjomin; in Spain as Biodramina; in Thailand as Daimenin; in Israel as Travamin; in Pakistan as Gravinate; and in Ethiopia as dimenhydrinate. Popular culture
Modest Mouse produced a song titled "Dramamine" on their 1996 debut album This Is a Long Drive for Someone with Nothing to Think About. The song uses side effects of the drug as a metaphor for the deteriorating state of a personal relationship.
Extremities may refer to:

Anatomy
The distal limb (forearm or lower leg) of a tetrapod animal, more specifically its distalmost portion, including:
Hand, a prehensile, multi-digited organ at the distal end of upper limb (arm) of bipedal primates (especially humans) that is highly adapted for grasping and fine manipulation of objects
Foot, the terminal portion of a quadruped tetrapods limb that mainly bears weight and allows terrestrial locomotion. In toe-walking ungulates, the term typically refers to the hoofed portion of the foot. Paw, a furry, padded foot with claws, common in many quadruped animals
Appendage, any external body part that protrudes outwards from an organisms core, such as a limb, tail, ear, nose, horn/antler, external genitalia, antenna, tusk/mouthpart or raptorial

Other
Extremities (play), a 1982 play by William Mastrosimone
Extremities (film), a 1986 film based on the play

See also
Extreme (disambiguation)