It was originally developed for adults with focal seizures, but failed a Phase III trial.In December 2001, the European Medicines Agency (EMA) granted stiripentol orphan drug status (designation number EU/3/01/071) for the treatment of severe myoclonic epilepsy of infancy (SMEI, also known as Dravets syndrome) in children and in January 2007, the EMA granted the drug a marketing authorisation for use of the drug as an add-on to other anti-seizure drugs. It was approved in Canada for this use in May 2013. As of 2017, it was also approved for this use in Japan.In August 2018, stiripentol was approved by the US Food and Drug Administration (FDA) as an adjunctive therapy for Dravet Syndrome. Society and culture
Economics
Prior to approval in the US, parents of children with Dravet Syndrome were paying around $1,000 for a month supply to obtain it from Europe. References
External links
"Stiripentol". Drug Information Portal. U.S. National Library of Medicine.
Macrodontia may refer to:

Macrodontia (tooth), a tooth disorder where the teeth are larger than normal
Macrodontia (beetle), a genus of beetles

See also
Macrodonta (disambiguation)