Blood flow is restored most rapidly in the first day or two after a PE. Improvement slows thereafter and some deficits may be permanent. There is controversy over whether small subsegmental PEs need treatment at all and some evidence exists that patients with subsegmental PEs may do well without treatment.Once anticoagulation is stopped, the risk of a fatal pulmonary embolism is 0.5% per year.Mortality from untreated PEs was said to be 26%. This figure comes from a trial published in 1960 by Barrit and Jordan, which compared anticoagulation against placebo for the management of PE. Barritt and Jordan performed their study in the Bristol Royal Infirmary in 1957. This study is the only placebo-controlled trial ever to examine the place of anticoagulants in the treatment of PE, the results of which were so convincing that the trial has never been repeated as to do so would be considered unethical. That said, the reported mortality rate of 26% in the placebo group is probably an overstatement, given that the technology of the day may have detected only severe PEs. Predicting mortality
The PESI and sPESI (= simplified Pulmonary Embolism Severity Index) scoring tools can estimate mortality of patients. The Geneva prediction rules and Wells criteria are used to calculate a pre-test probability of patients to predict who has a pulmonary embolism. These scores are tools to be used with clinical judgment in deciding diagnostic testing and types of therapy. The PESI algorithm comprises 11 routinely available clinical variables.
Acneiform eruptions
Acneiform eruptions are caused by changes in the pilosebaceous unit.Acne aestivalis (Mallorca acne)
Acne conglobata
Acne cosmetica (cosmetic acne)
Acne fulminans (acute febrile ulcerative acne)
Acne keloidalis nuchae (acne keloidalis, dermatitis papillaris capillitii, folliculitis keloidalis, folliculitis keloidis nuchae, nuchal keloid acne)
Acne mechanica
Acne medicamentosa
Acne miliaris necrotica (acne varioliformis)
Acne vulgaris (acne simplex)
Acne with facial edema (solid facial edema)
Blepharophyma
Erythrotelangiectatic rosacea (erythematotelangiectatic rosacea, vascular rosacea)
Excoriated acne (acne excoriée des jeunes filles, Pickers acne)
Glandular rosacea
Gnathophyma
Gram-negative rosacea
Granulomatous facial dermatitis
Granulomatous perioral dermatitis
Halogen acne
Hidradenitis suppurativa (acne inversa, pyoderma fistulans significa, Verneuils disease)
Idiopathic facial aseptic granuloma
Infantile acne
Lupoid rosacea (granulomatous rosacea, micropapular tuberculid, rosacea-like tuberculid of Lewandowsky)
Lupus miliaris disseminatus faciei
Metophyma
Neonatal acne (acne infantum, acne neonatorum, neonatal cephalic pustulosis)
Occupational acne
Oil acne
Ocular rosacea (ophthalmic rosacea, ophthalmorosacea)
Otophyma
Periorificial dermatitis
Persistent edema of rosacea (chronic upper facial erythematous edema, Morbihans disease, rosaceous lymphedema)
Phymatous rosacea
Pomade acne
Papulopustular rosacea (inflammatory rosacea)
Perifolliculitis capitis abscedens et suffodiens (dissecting cellulitis of the scalp, dissecting folliculitis, perifolliculitis capitis abscedens et suffodiens of Hoffman)
Perioral dermatitis
Periorbital dermatitis (periocular dermatitis)
Pyoderma faciale (rosacea fulminans)
Rhinophyma
Rosacea (acne rosacea)
Rosacea conglobata
Synovitis–acne–pustulosis–hyperostosis–osteomyelitis syndrome (SAPHO syndrome)
Steroid rosacea
Tar acne
Tropical acne

Autoinflammatory syndromes
Autoinflammatory syndromes are a group of inherited disorders characterized by bouts of inflammatory skin lesions and periodic fevers. Blau syndrome  
Chronic infantile neurologic cutaneous and articular syndrome
Familial cold urticaria (familial cold autoinflammatory syndrome)
Familial Mediterranean fever
Hyper-IgD syndrome
Majeed syndrome
Muckle–Wells syndrome
TNF receptor associated periodic syndrome (familial Hibernian fever, TRAPS, tumor necrosis factor receptor associated periodic syndrome)

Chronic blistering
Chronic blistering cutaneous conditions have a prolonged course and present with vesicles and bullae.