It has been hypothesized that this could be due to facial hypertrichosis.Hypertrichosis (often mistakenly classified as hirsutism) is a well documented condition in horses with a hormonal disorder of the hypothalamus, called Cushings disease. It is the most common endocrine disease of the middle-aged to older horse, often resulting in fatal laminitis. It can be successfully controlled by medications if diagnosed early. See also
Jesús Aceves, the first person with hypertrichosis to perform in the UK in thirty years. Stephan Bibrowski (1890–1932), known as Lionel the Lion-faced Man. Krao Farini (1876–1926), known as The Missing Link. Fedor Jeftichew (1868–1904), known as Jo-Jo the Dog-Faced Boy. Human Nature, a 2001 American-French film where one of the main characters has hypertrichosis. Fur: An Imaginary Portrait of Diane Arbus, a 2006 American film where one of the main characters has hypertrichosis. Milo, a 2012 (Netherlands) movie about a 10-year-old boy with hypersensitive skin. Moon of Desire, a 2014 Filipino TV drama with a girl that has hypertrichosis as the main protagonist. The True Adventures of Wolfboy, a 2019 Drama Movie about a 13-year-old boy that has hypertrichosis. References
External links

The Hairy Family of Burma
Neuropathology
Microscopic features of PKAN include high levels of iron in the globus pallidus and the pars reticulata of substantia nigra, evident as a characteristic rust-brown discoloration in a pattern called the eye-of-the-tiger sign; lipofuscin and neuromelanin concentrated in the iron-accumulating areas; oval, nonnucleated structures representing swollen axons whose cytoplasm swells with vacuoles, referred to as spheroids, axon schollen, or neuroaxonal dystrophy; and Lewy bodies. Treatment
Phosphopantothenate has been shown to treat PKAN in a human, and also in a mouse model of the disease. Pantethine (a precursor of pantetheine) has been studied and shown to be effective in a mouse and in a fruit fly model of the disease. Prognosis
Survival rates for those diagnosed with typical PKAN, and left untreated is 11.18 years with a standard deviation of 7.8 years. A study reporting good outcomes in a single patient with late onset PKAN has been performed. Epidemiology
Prevalence data regarding this disorder remains incomplete, however it is estimated that anywhere between 1 in 1,000,000 to 3 in 1,000,000 individuals will be affected by this disorder (based upon observed cases in a population), but once again this is only an estimate as the disease is so rare it is difficult to statistically and accurately ascertain. History
PKAN was first described by Hallervorden and Spatz (1922). Their discovery was brought about by a diagnosis of a family of 12 in which five sisters exhibited progressively increasing dementia and dysarthria. Autopsies revealed brown discolorations in different areas of the brain (particularly of interest were the globus pallidus and substantia nigra regions).