For a sufficiently strong storm, air may sink over a layer deep enough to suppress cloud formation, thereby creating a clear "eye". Weather in the eye is normally calm and free of convective clouds, although the sea may be extremely violent. The eye is normally circular and is typically 30–65 km (19–40 mi) in diameter, though eyes as small as 3 km (1.9 mi) and as large as 370 km (230 mi) have been observed.The cloudy outer edge of the eye is called the "eyewall". The eyewall typically expands outward with height, resembling an arena football stadium; this phenomenon is sometimes referred to as the "stadium effect". The eyewall is where the greatest wind speeds are found, air rises most rapidly, clouds reach their highest altitude, and precipitation is the heaviest. The heaviest wind damage occurs where a tropical cyclones eyewall passes over land.In a weaker storm, the eye may be obscured by the central dense overcast, which is the upper-level cirrus shield that is associated with a concentrated area of strong thunderstorm activity near the center of a tropical cyclone.The eyewall may vary over time in the form of eyewall replacement cycles, particularly in intense tropical cyclones. Outer rainbands can organize into an outer ring of thunderstorms that slowly moves inward, which is believed to rob the primary eyewall of moisture and angular momentum. When the primary eyewall weakens, the tropical cyclone weakens temporarily.
Rib and vertebrae anomalies
Intracranial calcification
Skeletal abnormalities: bifid ribs, kyphoscoliosis, early calcification of falx cerebri (diagnosed with AP radiograph)
Distinct faces: frontal and temporoparietal bossing, hypertelorism, and mandibular prognathism
Bilateral ovarian fibromas
10% develop cardiac fibromas

Cause
Mutations in the human homologue of Drosophila patched (PTCH1), a tumor suppressor gene on chromosome 9, were identified as the underlying genetic event in this syndrome. Diagnosis
Diagnosis of NBCCS is made by having two major criteria or one major and two minor criteria. [1]
The major criteria consist of the following:

more than 2 BCCs or 1 BCC in a person younger than 20 years;
odontogenic keratocysts of the jaw
3 or more palmar or plantar pits
ectopic calcification or early (<20 years) calcification of the falx cerebri
bifid, fused, or splayed ribs
first-degree relative with NBCCS.The minor criteria include the following:

macrocephaly. congenital malformations, such as cleft lip or palate, frontal bossing, eye anomaly (cataract, coloboma, microphthalmia, nystagmus). other skeletal abnormalities, such as Sprengel deformity, pectus deformity, polydactyly, syndactyly or hypertelorism. radiologic abnormalities, such as bridging of the sella turcica, vertebral anomalies, modeling defects or flame-shaped lucencies of hands and feet. ovarian and cardio fibroma or medulloblastoma (the latter is generally found in children below the age of two).People with NBCCS need education about the syndrome, and may need counseling and support, as coping with the multiple BCCs and multiple surgeries is often difficult. They should reduce UV light exposure, to minimize the risk of BCCs. They should also be advised that receiving Radiation therapy for their skin cancers may be contraindicated.