Persistent antisocial behavior, as well as a lack of regard for others in childhood and adolescence, is known as conduct disorder and is the precursor of ASPD. About 25–40% of youths with conduct disorder will be diagnosed with ASPD in adulthood.Conduct disorder (CD) is a disorder diagnosed in childhood that parallels the characteristics found in ASPD and is characterized by a repetitive and persistent pattern of behavior in which the basic rights of others or major age-appropriate norms are violated. Children with the disorder often display impulsive and aggressive behavior, may be callous and deceitful, and may repeatedly engage in petty crime such as stealing or vandalism or get into fights with other children and adults. This behavior is typically persistent and may be difficult to deter with threat or punishment. Attention deficit hyperactivity disorder (ADHD) is common in this population, and children with the disorder may also engage in substance use. CD is differentiated from oppositional defiant disorder (ODD) in that children with ODD do not commit aggressive or antisocial acts against other people, animals, and property, though many children diagnosed with ODD are subsequently re-diagnosed with CD.Two developmental courses for CD have been identified based on the age at which the symptoms become present. The first is known as the "childhood-onset type" and occurs when conduct disorder symptoms are present before the age of 10 years.
Risk Factors
Infection with certain strains of Neisseria gonorrhoeae
Prolonged infection
Female sex (due to asymptomatic infection, and therefore prolonged infection)
Sexual promiscuity
Immune system deficiencies
Infection during menstruation, pregnancy, or in the puerperium period

Symptoms
Fever
Migratory arthralgias
Hemorrhagic pustules
Tenosynovitis
Rarely headache, neck stiffness, and visual changes (associated with meningitis)

Treatment
Treatment typically consists of cephalosporin and fluoroquinolone antibiotics. Gonococcemia is typically treated with intravenous or intramuscular cephalosporin antibiotics. Approximately 10-30% of gonorrheal infections present with a co-infection of chlamydia, so it is common to add a one-time dose of oral azithromycin or doxycycline for coverage of Chlamydia trachomatis. Bacterial resistance to antibiotics is increasingly common in Neisseria gonorrhoeae, so it is often advised to check susceptibility of the bacterial culture and then adjust the antibiotic therapy as needed. Pathogenesis
Neisseria gonorrhoeae is transmitted during sexual contact with an infected individual. The bacteria invade the non-ciliated columnar epithelium of the urogenital tract, oral mucosa, or anal mucosa following exposure. Invasion of the host cells is made possible due to virulence factors such as Pili, LOS, Opa, and others. Similarly, these virulence factors can be used for avoiding the host immune system, which may explain prolonged infection, bacterial resistance, and gonococcemia. See also
Primary gonococcal dermatitis
List of cutaneous conditions


== References ==