Patch testing is recommended by some in cases which are resistant to treatment and where allergic contact dermatitis is suspected. Prognosis
Most cases of angular cheilitis respond quickly when antifungal treatment is used. In more long standing cases, the severity of the condition often follows a relapsing and remitting course over time. The condition can be difficult to treat and can be prolonged. Epidemiology
AC is a relatively common condition, accounting for between 0.7 – 3.8% of oral mucosal lesions in adults and between 0.2 – 15.1% in children, though overall it occurs most commonly in adults in the third to sixth decades of life. It occurs worldwide, and both males and females are affected. Angular cheilitis is the most common presentation of fungal and bacterial infections of the lips. Etymology
The term "angular cheilitis" is from Ancient Greek, χείλος meaning lip and -itis meaning inflammation. References


== External links ==
Adapalene/benzoyl peroxide, sold under the brand name Epiduo among others, is a fixed-dose combination medication for the treatment of severe acne vulgaris. It consists of a combination of adapalene and benzoyl peroxide in a topical gel formulation. Medical uses
Adapalene/benzoyl peroxide is indicated for the topical treatment of acne vulgaris. Side effects
Commonly reported side effects include the following:
Skin redness
Scaling
Dry skin
Contact dermatitis
Skin irritation
Stinging
Burning

Research
Meta-analysis of clinical trials has shown this combined therapy to be more effective than either of its ingredients by themselves.The use of adapalene/benzoyl peroxide in combination with oral antibiotics (lymecycline) has been studied; the combination was well tolerated and showed an improved success rate compared to those receiving only antibiotics (47.6% vs. 33.7%, P = 0.002). References
External links
"Adapalene mixture with benzoyl peroxide". Drug Information Portal. U.S. National Library of Medicine.