It was similarly merged into autism spectrum disorder in the International Classification of Diseases (ICD-11) as of 2021.There is no single treatment, and the UKs National Health Service (NHS) guidelines suggest that treatment of any form of autism should not be a goal, since autism is not a disease that can be removed or cured. According to the Royal College of Psychiatrists, while co-occurring conditions might require treatment, management of autism itself is chiefly about the provision of the education, training and social support/care required to improve the persons ability to function in the everyday world. The effectiveness of particular interventions for autism is supported by only limited data. Interventions may include social skills training, cognitive behavioral therapy, physical therapy, speech therapy, parent training, and medications for associated problems, such as mood or anxiety. Autistic characteristics tend to become less obvious in adulthood, but social and communication difficulties usually persist.Some autistic people,  as well as a number of researchers, have advocated a shift in attitudes toward the view that autism spectrum disorder is a difference, rather than a disease that must be treated or cured. Critics have bemoaned the entrenchment of some of these groups opinions.In 2015, Aspergers was estimated to affect 37.2 million people globally, or about 0.5% of the population. The exact percentage of people affected is not firmly established. Autism spectrum disorder is diagnosed in males more often than females, and females are typically diagnosed at a later age.
Contraindications
Contradindications include:
Hypersensitivity to trihexyphenidyl
Narrow angle glaucoma
Ileus (disruption of the normal propulsive ability of the intestine)
Caution: People with obstructive diseases of the urogenital tract, people with a known history of seizures and those with potentially dangerous tachycardia
People under 18 years of age should not be treated due to a lack of clinical experience. People should allow a period to adjust to the dose when first starting trihexyphenidyl and when the dose has been increased or added to a regimen with other drugs because acute somnolence and accumulated fatigue can make it particularly dangerous to operate an automobile, heavy machinery etc. Adverse effects
Dose-dependent side effects are frequent, but typically lessen over time as the body adapts to the medication. All of the following symptoms considered, Artane has been shown to dramatically and consistently improve neurologic defects in people aged 16–86 over the course of five years. People who are older or who have psychiatric conditions may become confused or develop delirium. Side effects include but are not limited to:
Central nervous system: drowsiness, vertigo, headache, and dizziness are frequent. With high doses nervousness, agitation, anxiety, delirium, and confusion are noted. Trihexyphenidyl may be abused due to a short acting mood-elevating and euphoric effect. The normal sleep architecture may be altered (REM sleep depression). Trihexyphenidyl may lower the seizure-threshold. Peripheral side effects: dry mouth, impaired sweating, abdominal discomfort, nausea, and constipation are frequent. Tachycardia or heart palpitations (fast heart rate) may be noted. Allergic reactions are rare, but may occur.