Callosities arise naturally and are present even in late-term whale fetuses, although the work of lice digging into the surface of the skin may make them more jagged and hard over time.Callosities are found on the upper surface of the whales head, above the eyes, on the jawline and chin and surrounding the blowholes. Callosities form a unique pattern on every right whale and though callosities which are overgrown break off, the patterns do not change over a lifetime. This makes them a very useful tool for the purposes of photo-identification and conservation.The evolutionary significance of callosities is unknown. Male right whales have a higher density of callosities than females. Males have been observed scratching one another with their callosities and it has been suggested by Payne & Dorsey (1983) that they are a sexually dimorphic feature, used for intra-specific sexual aggression. That explanation is not entirely satisfactory, because it does not account for the appearance of callosities in females. It has been proposed that the barnacles attached to callosities are important in helping fend off attacks by orcas. See also
Callus

Notes
References
Steudel, K (1981). "Functional Aspects of Primate Pelvic Structure: A Multivariate Approach" (PDF). American Journal of Physical Anthropology. 55 (3): 399–410. doi:10.1002/ajpa.1330550314. PMID 6791507. Archived from the original (PDF) on 2010-06-10. Retrieved 2009-07-19. Callosities by Mason T. Weinrich in the Encyclopedia of Marine Mammals. ISBN 0-12-551340-2. A Dictionary of Zoology 1999, Oxford University Press 1999
"On Butts and Baboons". Artsibasheva, A.  http://monkeybuiznezz.wordpress.com/2012/09/27/on-butts-and-baboons/
Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. It is used together with a diabetic diet and exercise. It is not indicated for use by itself in type 1 diabetes. It is taken by mouth. Effects generally begin within half an hour and can last for up to a day.Common side effects include nausea, diarrhea, low blood sugar, and headache. Other side effects include sleepiness, skin rash, and shakiness. The dose may need to be adjusted in those with liver or kidney disease. Use during pregnancy or breastfeeding is not recommended. It works by stimulating the pancreas to release insulin and increases tissue sensitivity to insulin.Glipizide was approved for medical use in the United States in 1984. It is available as a generic medication. In 2020, it was the 49th most commonly prescribed medication in the United States, with more than 13 million prescriptions. Mechanism of action
Glipizide sensitizes the beta cells of pancreatic islets of Langerhans insulin response, meaning that more insulin is released in response to glucose than would be without glipizide ingestion. Glipizide acts by partially blocking potassium channels among beta cells of pancreatic islets of Langerhans. By blocking potassium channels, the cell depolarizes, which results in the opening of voltage-gated calcium channels. The resulting calcium influx encourages insulin release from beta cells. History
It was patented in 1969 and approved for medical use in 1971. Glipizide was approved for medical use in the United States in 1984.