Paranoia perceptions and behavior may be part of many mental illnesses, such as depression and dementia, but they are more prevalent in three mental disorders: paranoid schizophrenia, delusional disorder (persecutory type), and paranoid personality disorder. Treatment
Paranoid delusions are often treated with antipsychotic medication, which exert a medium effect size. Cognitive behavioral therapy (CBT) improves paranoid delusions relative to control conditions according to a meta-analysis. A meta-analysis of 43 studies reported that metacognitive training (MCT) reduces (paranoid) delusions at a medium to large effect size relative to control conditions. History
The word paranoia comes from the Greek παράνοια (paranoia), "madness", and that from παρά (para), "beside, by" and νόος (noos), "mind". The term was used to describe a mental illness in which a delusional belief is the sole or most prominent feature. In this definition, the belief does not have to be persecutory to be classified as paranoid, so any number of delusional beliefs can be classified as paranoia. For example, a person who has the sole delusional belief that they are an important religious figure would be classified by Kraepelin as having pure paranoia. The word “paranoia” is associated from the Greek word “para-noeo”. Its meaning was "derangement", or "departure from the normal". However, the word was used strictly and other words were used such as "insanity" or "crazy", as these words were introduced by Aurelius Cornelius Celsus. The term “paranoia” first made an appearance during plays of Greek tragedians, and was also used by sufficient individuals such as Plato and Hippocrates.
Neurologic examination should assess cognitive and mental abilities, cranial nerve function, motor function, deep tendon reflexes, sensory function, coordination, and gait (if appropriate).Genetic testing

See also
Epilepsy Phenome/Genome Project

References
External links

Bilateral Frontalparietal Polymicrogyria at NIHs Office of Rare Diseases