Outdoor activities such as hiking, camping, or hunting where plague-infected animals may be found, increase the risk of contracting septicemic plague, and so do certain occupations such as veterinary or other animal-related work. Diagnosis
A doctor or veterinarian will perform a physical exam which includes asking about the medical history and possible sources of exposure. The following possible test could include:

Blood samples (detecting antibodies)
Culture samples of body fluids (check for the bacteria Yersinia pestis)
Kidney and liver testing
Checking lymphatic system for signs of infection
Examining body fluids for abnormal signs
Checking for swelling
Checking for signs of dehydration
Checking for fever
Checking for lung infection

Prevention
The following steps and precautions should be used to avoid infection of the septicemic plague:
Caregivers of infected patients should wear masks, gloves, goggles and gowns
Take antibiotics if close contact with infected patient has occurred
Use insecticides throughout house
Avoid contact with dead rodents or sick cats
Set traps if mice or rats are present around the house
Do not allow family pets to roam in areas where plague is common
Flea control and treatment for animals (especially rodents)

Treatment
Starting antibiotics early is a first step in treating septicemic plague in humans. One of the following antibiotics may be used:
Streptomycin
Gentamicin
Tetracycline or Doxycycline
Chloramphenicol
CiprofloxacinLymph nodes may require draining and the patient will need close monitoring.In animals, antibiotics such as tetracycline or doxycycline can be used. Intravenous drip may be used to assist in dehydration scenarios. Flea treatment can also be used. In some cases euthanasia may be the best option for treatment and to prevent further spreading. Prognosis
Untreated septicemic plague is almost always fatal.
Secondary hyperparathyroidism  is the medical condition of excessive secretion of parathyroid hormone (PTH) by the parathyroid glands in response to hypocalcemia (low blood calcium levels), with resultant hyperplasia of these glands. This disorder is primarily seen in patients with chronic kidney failure. It is sometimes abbreviated "SHPT" in medical literature. Signs and symptoms
Bone and joint pain are common, as are limb deformities. The elevated PTH has also pleiotropic effects on the blood, immune system, and neurological system. Cause
Chronic kidney failure is the most common cause of secondary hyperparathyroidism. Failing kidneys do not convert enough vitamin D to its active form, and they do not adequately excrete phosphate. When this happens, insoluble calcium phosphate forms in the body and removes calcium from the circulation. Both processes lead to hypocalcemia and hence secondary hyperparathyroidism. Secondary hyperparathyroidism can also result from malabsorption (chronic pancreatitis, small bowel disease, malabsorption-dependent bariatric surgery) in that the fat-soluble vitamin D can not get reabsorbed. This leads to hypocalcemia and a subsequent increase in parathyroid hormone secretion in an attempt to increase the serum calcium levels. A few other causes can stem from inadequate dietary intake of calcium, a vitamin D deficiency, or steatorrhea. Diagnosis
The PTH is elevated due to decreased levels of calcium or 1,25-dihydroxy-vitamin D3. It is usually seen in cases of chronic kidney disease or defective calcium receptors on the surface of parathyroid glands. Treatment
If the underlying cause of the hypocalcemia can be addressed, the hyperparathyroidism will resolve.