Livedoid vasculopathy  is a chronic cutaneous disease seen predominantly in young to middle-aged women. One acronym used to describe its features is "Painful purpuric ulcers with reticular pattern of the lower extremities" (PURPLE). It can be divided into a primary (or idiopathic) form and a secondary form, which has been associated with a number of diseases, including chronic venous hypertension and varicosities. : 343

See also
List of cutaneous conditions
Livedo
Livedo reticularis
Livedoid dermatitis

References
External links

DermNet vascular/livedoid-vasculitis
Nathalie syndrome is a rare genetic developmental defect during embryogenesis disorder and is thought to be hereditary.In 1975 a physician described four siblings in a Dutch family with symptoms of the condition; the condition was named after the oldest sibling.According to Orphanet, the condition occurs in 1 in 1 million people.Children with this condition appear younger than their age. Nathalie syndrome can cause disability and death around early or mid adulthood. Sudden death, cardiomyopathy, and heart failure have been reported in some cases. == References ==