There is not yet sufficient evidence on how effective this combined pentavalent vaccine is in relation to the individual vaccines. References
Further reading
Ramsay M, ed. (2013). "Chapter 16: Haemophilus influenzae type b (Hib)". Immunisation against infectious disease. Public Health England. External sources
"Haemophilus Influenzae Type b (Hib) Vaccine Information Statement". U.S. Centers for Disease Control and Prevention (CDC). 10 August 2021. "Haemophilus B Conjugate Vaccine (Meningococcal Protein Conjugate)". U.S. Food and Drug Administration (FDA). 24 April 2019. "Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)". U.S. Food and Drug Administration (FDA). 24 April 2019. "Hiberix". U.S. Food and Drug Administration (FDA). 3 October 2019.
Klismaphilia (or klysmaphilia), from the Greek words κλύσμα ("enema", from κατακλυσμός, "deluge, flood") and φιλία ("love"), is a paraphilia involving enjoyment of, and sexual arousal from, enemas. History
The term klismaphilia was coined in 1973 by Dr. Joanne Denko, an early investigator in this field, in her article "Klismaphilia: Enema as a Sexual Preference[:] Report of Two Cases," to describe the activities of some of her patients, whom she referred to as klismaphiliacs. Klismaphile has come into use as a synonym for klismaphiliac. Manifestation
Klismaphiles might gain pleasure from a large, water distended belly or the feeling of internal pressure. An enema fetish may include the sexual attraction to the equipment, processes, environments, situations, or scenarios, and some may be sexually aroused by the preparations, such as by the feel and smell of a latex rubber or plastic syringe, by the smell of soapsuds enema solution, or by preparing the recipient. Often, klismaphiles report discovering these desires after a chance administration of an enema sometime in their childhood, but some do report discovering these feelings later on. Klismaphiles can gain satisfaction of enemas through fantasies, by actually receiving or giving one, or through the process of eliminating steps to being administered one (e.g., under the pretense of being constipated). Usually, klismaphiles carry out normal lives and successfully engage in this behavior secretly. An enema can be an auxiliary to, or a substitute for, genital sexual activity.That some women use enemas while masturbating was documented by Alfred Kinsey in "Sexual Behavior in the Human Female."