Individuals will be less likely to invest money and effort towards growth in such unstable and violent conditions. One of the possible proves might be the study of Baten and Gust that used "regicide" as measurement unit to approximate the influence of interpersonal violence and depict the influence of high interpersonal violence on economic development and level of investments. The results of the research prove the correlation of the human capital and the interpersonal violence.In 2016, the Institute for Economics and Peace, released the Economic Value of Peace report, which estimates the economic impact of violence and conflict on the global economy, the total economic impact of violence on the world economy in 2015 was estimated to be $13.6 trillion in purchasing power parity terms. Religion and politics
Religious and political ideologies have been the cause of interpersonal violence throughout history.
Brimonidine is a medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. In rosacea it improves the redness. It is used as eye drops or applied to the skin.Common side effects when used in the eyes include itchiness, redness, and a dry mouth. Common side effects when used on the skin include redness, burning, and headaches. More significant side effects may include allergic reactions and low blood pressure. Use in pregnancy appears to be safe. When applied to the eye it works by decreasing the amount of aqueous humor made while increasing the amount that drains from the eye. When applied to the skin it works by causing blood vessels to contract.Brimonidine was patented in 1972 and came into medical use in 1996. It is available as a generic medication. In 2019, it was the 217th most commonly prescribed medication in the United States, with more than 2 million prescriptions. Medical uses
Brimonidine is indicated for the lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is also the active ingredient of brimonidine/timolol along with timolol maleate. A 2017 Cochrane review found insufficient evidence to determine if brimonidine slows optic nerve damage.In 2013, the FDA approved topical application of brimonidine 0.33% gel for persistent facial redness of rosacea. Mechanism of action
Brimonidine is an α2 adrenergic agonist.α2 agonists, through the activation of a G protein-coupled receptor, inhibit the activity of adenylate cyclase. This reduces cAMP and hence aqueous humour production by the ciliary body.