WHO asserts that a water level of 0.01 mg/L (10 ppb) poses a risk of 6 in 10,000 chance of lifetime skin cancer risk and contends that this level of risk is acceptable.One of the worst incidents of arsenic poisoning via well water occurred in Bangladesh, which the World Health Organization called the "largest mass poisoning of a population in history" recognized as a major public health concern. The contamination in the Ganga-Brahmaputra fluvial plains in India and Padma-Meghna fluvial plains in Bangladesh demonstrated adverse impacts on human health.Mining techniques such as hydraulic fracturing may mobilize arsenic in groundwater and aquifers due to enhanced methane transport and resulting changes in redox conditions, and inject fluid containing additional arsenic. Groundwater
In the US, the U.S. Geological Survey estimates that the median groundwater concentration is 1 μg/L or less, although some groundwater aquifers, particularly in the western United States, can contain much higher levels. For example, median levels in Nevada were about 8 μg/L but levels of naturally occurring arsenic as high as 1000 μg/L have been measured in the United States in drinking water.Geothermally active zones occur at hotspots where mantle-derived plumes ascend, such as in Hawaii and Yellowstone National Park, US. Arsenic is an incompatible element (does not fit easily into the lattices of common rock-forming minerals). Concentrations of arsenic are high mainly in geothermal waters that leach continental rocks.
In pediatric medicine, acrocephalosyndactyly is the common presentation of craniosynostosis and syndactyly. When there is also polydactyly the classification is acrocephalopolysyndactyly. Cause
Diagnosis
Classification
It has several different types:

type I – Apert syndrome: 577 
type II – Crouzon syndrome: 577 
type III – Saethre–Chotzen syndrome
type IV – Goodman Syndrome
type V – Pfeiffer syndromeA related term, acrocephalopolysyndactyly, refers to the inclusion of polydactyly to the presentation. It also has multiple types:

type I – Noack syndrome; now classified with Pfeiffer syndrome
type II – Carpenter syndrome
type III – Sakati–Nyhan–Tisdale syndrome
type IV – Goodman syndrome; now classified with Carpenter syndrome
type V – Pfeiffer syndromeIt has been suggested that the distinction between "acrocephalosyndactyly" versus "acrocephalopolysyndactyly" should be abandoned. Treatment
See also
List of skin conditions
Oxycephaly

References
External links

Acrocephalosyndactylia at the US National Library of Medicine Medical Subject Headings (MeSH)