In trial, lysine restriction of 70–100 mg/kg/day in children less than 1 year of age, 45–80 mg/kg/day in children between 1–7 years of age, and 20–45 mg/kg/day in children older than 7 years of age were prescribed. Despite the potential of additional benefit from lysine restriction, vitamin B6 supplementation remains the main-stay of treatment given lack of studies thus far demonstrating the safety and efficacy of lysine restriction for this purpose. Monitoring
Plasma and cerebrospinal fluid levels of pipecolic acid are frequently elevated in patients with PDE, though it is a non-specific biomarker. α-aminodipic semialdehyde is elevated in urine and plasma and is a more specific biomarker for PDE. Improvements in these biomarkers have been reported with the implementation of a lysine-restricted diet. Initial studies evaluating the safety and efficacy of lysine restriction evaluated developmental and cognitive outcomes by age-appropriate tests and parental observations. References
External links

GeneReview/NCBI/NIH/UW entry on Pyridoxine-Dependent Seizures
Pyridoxine-dependent epilepsy. Genetics Home Reference. June 17, 2013.
In cases where cerebrospinal fluid builds up, such as in hydrocephalus, the fluid is commonly diverted to the peritoneal cavity by use of a shunt placed by surgery.Body fluid sampling from the peritoneal cavity is called peritoneocentesis. The peritoneal cavity is involved in peritoneal dialysis. See also
Lesser sac
Greater sac

References
External links
peritoneum at The Anatomy Lesson by Wesley Norman (Georgetown University)