In one study it was reported that people experienced side effects when taking bisphosphonates for six months, however the quality of evidence was low. None of these drugs should be used by people with severe kidney disease. Neridronate
Etidronate disodium The approved regimen is once daily for six months; a higher dose is more commonly used. No food, beverage, or medications should be consumed for two hours before and after taking. The course should not exceed six months, but repeat courses can be given after rest periods, preferably of three to six months duration. Pamidronate disodium in intravenous form: the approved regimen uses an infusion over four hours on each of three consecutive days, but a more commonly used regimen is over two to four hours for two or more consecutive or nonconsecutive days. Alendronate sodium is given as tablets once daily for six months; patients should wait at least 30 minutes after taking before eating any food, drinking anything other than tap water, taking any medication, or lying down (patient may sit). Tiludronate disodium is taken once daily for three months; they may be taken any time of day, as long as there is a period of two hours before and after resuming food, beverages, and medications. Risedronate sodium tablet taken once daily for 2 months is the prescribed regimen; patients should wait at least 30 minutes after taking before eating any food, drinking anything other than tap water, taking any medication, or lying down (patient may sit).
Myopericarditis is a combination of both myocarditis and pericarditis appearing in a single individual, namely inflammation of both the pericardium and the heart muscle. It can involve the presence of fluid in the heart. Risk factors
The appearance of myopericarditis is associated with infections such as acute tonsillitis, pneumonia, and gastroenteritis.Smallpox vaccination has been a known risk factor for myocarditis and pericarditis since the 1950s. In 1983, an incidence of myocarditis of 1 per 10 000 was reported among Finnish military personnel. Among US military service members vaccinated between December 2002 and March 2003 with Dryvax smallpox vaccine 18 cases of probable myopericarditis were reported, which was an incidence of 7.8 per 100 000 over 30 days.A meta-review from 2022 shows that the overall risk for myopericarditis after receiving a COVID-19 vaccine is low. In addition, the incidence of myopericarditis is significantly higher with a smallpox vaccination in comparison with a COVID-19 vaccination. The ACAM2000 smallpox vaccine has been known to cause myopericarditis in some people. Etymology
When ventricular function is normal, the term myopericarditis is used. Cases with impaired function are labeled perimyocarditis, though the two terms are often used interchangeably. Both will be reflected on an ECG.In a different naming scheme, inflammation that is predominantly pericarditis with some myocardial involvement is called myopericarditis, while predominant myocarditis with some pericardial involvement is called perimyocarditis. == References ==