Contrary to the solubilities above, methylprednisolone sodium succinate is soluble in water and alcohol, slightly soluble in acetone and insoluble in chloroform

Chemical properties
Methylprednisolone, or 6α-methylprednisolone, also known as 11β,17,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione, is a synthetic pregnane steroid and a derivative of hydrocortisone (11β,17α,21-trihydroxypregn-4-ene-3,20-dione) and prednisolone (11β,17α,21-trihydroxypregn-1,4-diene-3,20-dione). A variety of methylprednisolone esters with differing characteristics exist and have been marketed for medical use. They include methylprednisolone aceponate (Advantan), methylprednisolone acetate (Depo-Medrol), methylprednisolone succinate (Solu-Medrol), and methylprednisolone suleptanate (Medrosol, Promedrol). Synthesis
Synthetic steroids are synthesized from cholic acid and sapogenins obtained from cattle and plants, respectively. History, society and culture
Methylprednisolone was first synthesized and manufactured by The Upjohn Company (now Pfizer) and Food and Drug Administration (FDA) approved in the United States on 2 October 1957. The patent has since expired, and generics are now available. In 2021, it is ranked as the 153rd most commonly prescribed medication in the United States, with more than four million prescriptions. It has jumped four spots in the rankings from 2017. Methylprednisolone has been a prescribed therapy amidst the COVID-19 pandemic, but there is no evidence it is either safe or effective for this purpose. Research
Methylprednisolone has been a prescribed therapy amidst the COVID-19 pandemic, but there is no evidence it is either safe or effective for this purpose. References
External links
"Methylprednisolone". Drug Information Portal. U.S. National Library of Medicine.
Capillariasis is a disease caused by nematodes in the genus Capillaria. The two principal forms of the disease are:

Intestinal capillariasis, caused by Capillaria philippinensis
Hepatic capillariasis, caused by Capillaria hepatica


== References ==