Most patients have severe symptoms lasting a few weeks to six months. 15 to 50 percent of cases involve recurrent bouts of arthritis. Chronic arthritis or sacroiliitis occurs in 15–30 percent of cases. Repeated attacks over many years are common, and patients sometimes end up with chronic and disabling arthritis, heart disease, amyloid deposits, ankylosing spondylitis, immunoglobulin A nephropathy, cardiac conduction abnormalities, or aortitis with aortic regurgitation. However, most people with reactive arthritis can expect to live normal life spans and maintain a near-normal lifestyle with modest adaptations to protect the involved organs. Epidemiology
Because women may be underdiagnosed, the exact incidence of reactive arthritis is difficult to estimate. A few studies have been completed, though. In Norway between 1988 and 1990, the incidence was 4.6 cases per 100,000 for chlamydia-induced reactive arthritis and 5 cases per 100,000 for that induced by enteric bacteria. In 1978 in Finland, the annual incidence was found to be 43.6 per 100,000. History
When reactive arthritis appears in a triad that also includes ophthalmic and urogenital manifestations, the eponym "Reiters syndrome" is often applied; German physician Hans Conrad Julius Reiter described the condition in a soldier he treated during World War I. A number of physicians have suggested that the eponym is undeserved. Reiters Nazi Party affiliation, and in particular his involvement in forced human experimentation in the Buchenwald concentration camp (which, after his capture at the end of World War II, resulted in his prosecution in Nuremberg as a war criminal), have come to overshadow his medical accomplishments.
The first-century BC Latin poet Virgil, in his epic Aeneid, has the Cyclopes: "Brontes and Steropes and bare-limbed Pyracmon" toil under the direction of Vulcan (Hephaestus), in caves underneath Mount Etna and the Aeolian islands. Virgil describes the Cyclopes, in Vulcans smithy forging iron, making a thunderbolt, a chariot for Mars, and Pallass Aegis, with Vulcan interrupting their work to command the Cyclopes to fashion arms for Aeneas. The later Latin poet Ovid also has the Hesiodic Cyclopes Brontes and Steropes (along with a third Cyclops named Acmonides), work at forges in Sicilian caves.According to a Hellenistic astral myth, the Cyclopes were the builders of the first altar. The myth was a catasterism, which explained how the constellation the Altar (Ara) came to be in the heavens. According to the myth, the Cyclopes built an altar upon which Zeus and the other gods swore alliance before their war with the Titans. After their victory, "the gods placed the altar in the sky in commemoration", and thus began the practice, according to the myth, of men swearing oaths upon altars "as a guarantee of their good faith".According to the second-century geographer Pausanias, there was a sanctuary called the "altar of the Cyclopes" on the Isthmus of Corinth at a place sacred to Poseidon, where sacrifices were offered to the Cyclopes. There is no evidence for any other cult associated with the Cyclopes.