These may indicate that the disease has spread from the bone into the chest cavity. The breathing problems may be misdiagnosed as asthma, because the damage done to the lungs can cause the same types of changes to lung function testing as seen in asthma. Extension of the lesions into the chest may lead to the development of chylous pleural and pericardial effusions. Chyle is rich in protein and white blood cells that are important in fighting infection. The loss of chyle into the chest can have serious consequences, including infection, malnutrition, and respiratory distress and failure. These complications or their symptoms, such as difficulty breathing, chest pain, poor growth or weight loss, and infection have sometimes been the first indications of the condition. Causes
The specific cause of Gorhams disease remains unknown. Bone mass and strength are obtained and maintained through a process of bone destruction and replacement that occurs at the cellular level throughout a persons life. Cells called osteoclasts secrete enzymes that dissolve old bone, allowing another type of cells called osteoblasts to form new bone. Except in growing bone, the rate of breakdown equals the rate of building, thereby maintaining bone mass. In Gorhams disease, that process is disrupted.Gorham and Stout found that vascular anomalies always occupied space that normally would be filled with new bone and speculated that the presence of angiomatosis may lead to chemical changes in the bone.
From 1988 through 2010, analysis from the United States Government Accountability Office indicates that trusts have paid about 3.3 million claims valued at about $17.5 billion. Notable people
This is a partial list of notable people who have died from lung fibrosis associated with asbestos:

Bernie Banton, social justice advocate
Paul Gleason, Breakfast Club actor
Stephen Jay Gould, Harvard University professor, paleontologist, evolutionary biologist, and historian
Nellie Kershaw, first person diagnosed with asbestos-related disease, 1924
John MacDougall, politician
Steve McQueen, actor
Theodore Sturgeon, writer

References
External links

"Asbestos Toxicity". ATSDR Case Studies in Environmental Medicine. U.S. Department of Health and Human Services. "Asbestos health and safety". British Government Health and Safety Executive. "Asbestos Exposure". National Cancer Institute, USA. 2017-06-15. "Environmental Health Guidance Note — Asbestos" (PDF). Queensland Health. May 2002. Archived from the original (PDF) on 2012-02-27. Retrieved 2011-12-03. "Asbestos". IRIS — Integrated Risk Information System. US Environmental Protection Agency. 2013-03-15. CASRN 1332-21-4.