Primary cutaneous coccidioidomycosis is a skin condition caused by Coccidioides immitis following a definite history of inoculation or a colonized splinter found in the skin lesion. : 315

See also
Coccidioidomycosis
List of cutaneous conditions


== References ==
Infection spreads rapidly as the gases produced by the bacteria expand and infiltrate healthy tissue in the vicinity. Because of its ability to quickly spread to surrounding tissues, gas gangrene should be treated as a medical emergency. Gas gangrene is caused by bacterial exotoxin-producing clostridial species, which are mostly found in soil, and other anaerobes such as Bacteroides and anaerobic streptococci. These environmental bacteria may enter the muscle through a wound and subsequently proliferate in necrotic tissue and secrete powerful toxins that destroy nearby tissue, generating gas at the same time. A gas composition of 5.9% hydrogen, 3.4% carbon dioxide, 74.5% nitrogen, and 16.1% oxygen was reported in one clinical case.Gas gangrene can cause necrosis, gas production, and sepsis. Progression to toxemia and shock is often very rapid. Other types
Necrotizing fasciitis, also known as hemolytic streptococcal gangrene, is a very rare infection that spreads deep into the body along tissue planes. It is characterized by infection with S.pyogenes, a gram-positive cocci bacteria. Noma is a gangrene of the face common in Africa and Asia, with 99% of cases occurring there, whereas the disease is practically non-existent in other continents. Fournier gangrene is a type of necrotizing fasciitis that usually affects the genitals and groin. Venous limb gangrene may be caused by heparin-induced thrombocytopenia and thrombosis. Severe mesenteric ischemia may result in gangrene of the small intestine. Severe ischemic colitis may result in gangrene of the large intestine. Treatment
Treatment varies based on the severity and type of gangrene.