In some types of ED, abnormal development of parts of the eye can result in dryness of the eye, cataracts, and vision defects. Professional eye care can help minimize the effects of ED on vision. Similarly, abnormalities in the development of the ear may cause hearing problems. Respiratory infections can be more common because the normal protective secretions of the mouth and nose are not present. Precautions must be taken to limit infections. Genetics
ED can be classified by inheritance (autosomal dominant, autosomal recessive and X-linked) or by which structures are involved (hair, teeth, nails and/or sweat glands). There are several different types with distinct genetic causes:

Hay–Wells syndrome (Rapp–Hodgkin syndrome) and EEC syndrome are all associated with TP63. Hypohidrotic ectodermal dysplasia can be associated with EDA, EDAR and EDARADD. Margarita Island ectodermal dysplasia is associated with PVRL1. Ectodermal dysplasia with skin fragility is associated with PKP1. Cloustons hidrotic ectodermal dysplasia is associated with GJB6. Naegeli syndrome/Dermatopathia pigmentosa reticulariss is associated with KRT14. Pachyonychia congenita is caused by multiple keratins. Focal dermal hypoplasia is associated with PORCN. Ellis–van Creveld syndrome is associated with EVC. Palmoplantar ectodermal dysplasia refers to several different conditions selectively affecting the hands and feet.
Diagnosis
In terms of the clinical evaluation, clinical features are the classification method

Treatment
Management for this condition is symptom specific

Society and culture
Notable cases
Michael Berryman, American actor with hypohidrotic ectodermal dysplasia
Levi Hawken, New Zealand skateboarder and artist who became well known in 2011 in New Zealand for the "Nek minnit" viral video on YouTube

See also
List of cutaneous conditions
List of cutaneous conditions caused by mutations in keratins

References


== External links ==