In those with significant dependence, sudden discontinuation may result in withdrawal symptoms such as status epilepticus. Overdose
A midazolam overdose is considered a medical emergency and generally requires the immediate attention of medical personnel. Benzodiazepine overdose in healthy individuals is rarely life-threatening with proper medical support; however, the toxicity of benzodiazepines increases when they are combined with other CNS depressants such as alcohol, opioids, or tricyclic antidepressants. The toxicity of benzodiazepine overdose and the risk of death are also increased in the elderly and those with obstructive pulmonary disease or when used intravenously. Treatment is supportive; activated charcoal can be used within an hour of the overdose. The antidote for an overdose of midazolam (or any other benzodiazepine) is flumazenil. While effective in reversing the effects of benzodiazepines it is not used in most cases as it may trigger seizures in mixed overdoses and benzodiazepine dependent individuals.Symptoms of midazolam overdose can include:

Detection in body fluids
Concentrations of midazolam or its major metabolite, 1-hydroxymidazolam glucuronide, may be measured in plasma, serum, or whole blood to monitor for safety in those receiving the drug therapeutically, to confirm a diagnosis of poisoning in hospitalized patients, or to assist in a forensic investigation of a case of fatal overdosage. Patients with renal dysfunction may exhibit prolongation of elimination half-life for both the parent drug and its active metabolite, with accumulation of these two substances in the bloodstream and the appearance of adverse depressant effects.
It originates in the substitution of one Nordic capital (Stockholm, Sweden) for another (Helsinki, Finland). It entered popular culture when used in the Bruce Willis film Die Hard, by a doctor appearing on a television show and describing the phenomenon. The bumbling host says this refers to "Helsinki, Sweden", and the doctor corrects him, saying "Finland". History
Stockholm bank robbery
In 1973, Jan-Erik Olsson, a convict on parole, took four employees (three women and one man) of Kreditbanken, one of the largest banks in Stockholm, Sweden, hostage during a failed bank robbery. He negotiated the release from prison of his friend Clark Olofsson to assist him. They held the hostages captive for six days (23–28 August) in one of the banks vaults. When the hostages were released, none of them would testify against either captor in court; instead, they began raising money for their defense.Nils Bejerot, a Swedish criminologist and psychiatrist coined the term after the Stockholm police asked him for assistance with analyzing the victims reactions to the 1973 bank robbery and their status as hostages. As the idea of brainwashing was not a new concept, Bejerot, speaking on "a news cast after the captives release" described the hostages reactions as a result of being brainwashed by their captors. He called it Norrmalmstorgssyndromet (after Norrmalmstorg Square where the attempted robbery took place), meaning "the Norrmalmstorg syndrome"; it later became known outside Sweden as Stockholm syndrome.