Subacute cutaneous lupus erythematosus  is a clinically distinct subset of cases of lupus erythematosus that is most often present in white women aged 15 to 40, consisting of skin lesions that are scaly and evolve as poly-cyclic annular lesions or plaques similar to those of plaque psoriasis.Characteristically the lesions appear in sun-exposed areas such as the vee of the neckline or the forearms, but not the face. It may be brought on by sun-sensitizing medications, but is usually associated with autoimmune disorders such as rheumatoid arthritis and Sjögrens syndrome.Therapy generally involves sun avoidance and protection and topical corticosteroids. Sometimes systemic drug treatment is necessary. Besides corticosteroids other immunosuppressants such as methotrexate are also used.Lesions of SCLE may have an annular (shaped like a ring) configuration, with raised red borders and central clearing. See also
Lupus erythematosus
List of cutaneous conditions
List of human leukocyte antigen alleles associated with cutaneous conditions

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However supplementation with Vitamin A would be beneficial only in exceptional cases because normally the local catabolism of vitamin A will be the regulating factor. Squamous metaplasia of breast epithelia is known to be more prevalent in postmenopausal women (where it does not cause any problems at all). Staurosporine, a nonspecific protein kinase C inhibitor can induce squamous metaplasia in breast tissue while other known PKC inhibitors did not show this effect. cAMP stimulation can also induce squamous metaplasia. Research
Multiple imaging modalities may be necessary to evaluate abnormalities of the nipple-areolar complex.In two studies performed in Japan, high-resolution MRI with a microscopy coil yielding 0.137-mm in-plane resolution has been used to confirm the presence of abscesses, isolated fistulas and inflammation and to reveal their position in order to guide surgery. References
Further reading
Kasales CJ, Han B, Smith JS, Chetlen AL, Kaneda HJ, Shereef S (February 2014). "Nonpuerperal mastitis and subareolar abscess of the breast". AJR. American Journal of Roentgenology (review). 202 (2): W133–9. doi:10.2214/AJR.13.10551. PMID 24450694. S2CID 27952386.