Novolin is the brand name of three distinct insulin-containing products manufactured by Novo Nordisk:

Novolin 70/30, an insulin preparation containing mixed NPH and regular insulin, respectively
Novolin N, an insulin preparation containing NPH insulin
Novolin R, an insulin preparation containing regular insulin

See also
Insulin (medication)


== References ==
A vast amount of carbohydrate binding molecules (lectins) depend on correct glycosylation for appropriate binding; the selectins, involved in leukocyte extravasation, is a prime example. Their binding depends on a correct fucosylation of cell surface glycoproteins. Lack thereof leads to leukocytosis and increase sensitivity to infections as seen in SLC35C1-CDG(CDG-IIc); caused by a GDP-fucose (Fuc) transporter deficiency.All N-linked oligosaccharides originate from a common lipid-linked oligosaccharide (LLO) precursor, synthesized in the ER on a dolichol-phosphate (Dol-P) anchor. The mature LLO is transferred co-translationally to consensus sequence Asn residues in the nascent protein, and is further modified by trimming and re-building in the Golgi. Deficiencies in the genes involved in N-linked glycosylation constitute the molecular background to most of the CDGs. Type I defects involve the synthesis and transfer of the LLO
Type II defects impair the modification process of protein-bound oligosaccharides. Type I
Type II
The mature LLO chain is next transferred to the growing protein chain, a process catalysed by the oligosaccharyl transferase (OST) complex. Once transferred to the protein chain, the oligosaccharide is trimmed by specific glycosidases. This process is vital since the lectin chaperones calnexin and calreticulin, involved in protein quality, bind to the Glc1Man9GlcNAc-structure and assure proper folding. Lack of the first glycosidase (GCS1) causes CDG-IIb. Removal of the Glc residues and the first Man residue occurs in the ER. The glycoprotein then travels to the Golgi, where a multitude of different structures with different biological activities are formed.