It carries a quite small risk of central retinal artery obstruction, focal depigmentation in dark-skinned patients, and inadvertent ocular penetration. It is considered a simple and effective treatment option, one with high success rates. It may give the same results as surgical treatment (I&C). Larger, long-standing lesions are best treated surgically. Considering the surgical risks, steroid injection is believed to be a safer procedure in marginal lesions and lesions close to lacrimal punctum.One injection alone has a success rate of about 80%; if requested, a second injection can be given 1–2 weeks later. Carbon dioxide laser
Chalazion excision using a CO2 laser is also a safer procedure, with minimal bleeding and no eye patching  required. See also
Stye

References
External links

 Media related to Chalazion at Wikimedia Commons
The most common side effects with vonicog alfa (which may affect up to 1 in 10 patients) are dizziness, vertigo (a spinning sensation), dysgeusia (taste disturbances), tremor, rapid heartbeat, deep venous thrombosis (blood clot in a deep vein, usually in the leg), hypertension (high blood pressure), hot flush, vomiting, nausea (feeling sick), pruritus (itching), chest discomfort, sensations like numbness, tingling, pins and needles at the site of infusion, and an abnormal reading on the electrocardiogram (ECG). References
Further reading
AusPAR: Vonicog alfa. Therapeutic Goods Administration (TGA) (Report). October 2020. External links
"Vonicog alfa". Drug Information Portal. U.S. National Library of Medicine.