In animals such as horses and other working animals, saddle sores often form on either side of the withers, which is the area where the front of a saddle rests, and also in the girth area behind the animals elbow, where they are known as a girth gall. Saddle sores can occur over the loin, and occasionally in other locations. These sores are usually caused by ill-fitting gear, dirty gear, lack of proper padding, or unbalanced loads. Reducing friction is also of great help in preventing equine saddle sores. Where there is swelling but not yet open sores, the incidence of sore backs may be reduced by loosening the girth without immediately removing the saddle after a long ride, thus allowing normal circulation to return slowly. See also
Bicycling
Pack saddle


== References ==
Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin that covers the vulva. VIN is an intraepithelial neoplasia, and can disappear without treatment. VINs are benign but if the changes become more severe, there is a chance of cancer developing after many years, and so it is referred to as a precancerous condition. Classification
Medically speaking, the term denotes a squamous intraepithelial lesion of the vulva that shows dysplasia with varying degrees of atypia. The epithelial basement membrane is intact and the lesion is thus not invasive but has invasive potential. The terminology of VIN evolved over several decades. In 1989 the Committee on Terminology, International Society for the Study of Vulvar Disease (ISSVD) replaced older terminology such as vulvar dystrophy, Bowens disease, and Kraurosis vulvae by a new classification system for Epithelial Vulvar Disease:

Nonneoplastic epithelial disorders of vulva and mucosa:
Lichen sclerosus
Squamous hyperplasia
Other dermatoses
Mixed neoplastic and nonneoplastic disorders
Intraepithelial neoplasia
Squamous vulvar intraepithelial neoplasia (VIN), previously classified as VIN 1-3:Non-squamous intraepithelial neoplasia
Extramammary Pagets disease
Tumors of melanocytes, noninvasive
Invasive disease (vulvar carcinoma)The ISSVD further revised this classification in 2004, replacing the three-grade system  with a single-grade system in which only the high-grade disease is classified as VIN. VIN is subdivided into: (Robbins Pathological Basis of Disease, 9th Ed)
Classic vulvular intraepithelial neoplasia: associated with developing into the warty and basaloid type carcinoma. This is associated with carcinogenic genotypes of HPV and/or HPV persistence factors such as cigarette smoking or immunocompromised states.