Dystonic movements can augment hyperkinetic movements, especially when linked to voluntary movements.Blepharospasm is a type of dystonia characterized by the involuntary contraction of the muscles controlling the eyelids. Symptoms can range from a simple increased frequency of blinking to constant, painful eye closure leading to functional blindness.Oromandibular dystonia is a type of dystonia marked by forceful contractions of the lower face, which causes the mouth to open or close. Chewing motions and unusual tongue movements may also occur with this type of dystonia.Laryngeal dystonia or spasmodic dysphonia results from abnormal contraction of muscles in the voice box, resulting in altered voice production. Patients may have a strained-strangled quality to their voice or, in some cases, a whispering or breathy quality.Cervical dystonia (CD) or spasmodic torticollis is characterized by muscle spasms of the head and neck, which may be painful and cause the neck to twist into unusual positions or postures.Writers cramp and musicians cramp is a task-specific dystonia, meaning that it only occurs when performing certain tasks. Writers cramp is a contraction of hand and/or arm muscles that happens only when a patient is writing. It does not occur in other situations, such as when a patient is typing or eating. Musicians cramp occurs only when a musician plays an instrument, and the type of cramp experienced is specific to the instrument. For example, pianists may experience cramping of their hands when playing, while brass players may have cramping or contractions of their mouth muscles.
Lamivudine/tenofovir disoproxil, sold under the brand name Cimduo among others, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS in adults and children weighing more than 35 kilograms (77 lb). It contains lamivudine and tenofovir disoproxil. It is taken by mouth.Lamivudine/tenofovir was approved for medical use in the United States in February 2018. References
Further reading
"WHO Public Assessment Report: HA414 - Lamivudine/Tenofovir disoproxil fumarate - 300mg/300mg - Tablets - Mylan Laboratories Ltd - India". World Health Organization (WHO). Archived from the original on 26 March 2020. External links
"Lamivudine". Drug Information Portal. U.S. National Library of Medicine. "Tenofovir disoproxil". Drug Information Portal. U.S. National Library of Medicine. "Tenofovir disoproxil fumarate". Drug Information Portal. U.S. National Library of Medicine.