It has common features with other self-diagnosed "mystery syndromes" such as morgellons syndrome or multiple chemical sensitivity. There is no known underlying biological mechanism for the proposed syndrome, and its incidence is also unclear. A lack of clear diagnostic criteria and the variable reporting fraction in different health-care settings make the problem challenging to evaluate.Self-reported symptoms of post-finasteride syndrome include penile atrophy and tissue changes, decreased ejaculate volume and quality, libido loss, erectile dysfunction, loss of penile sensitivity, decreased orgasm sensation, dry skin, metabolic changes, muscle and strength loss, gynecomastia, depression, anxiety, panic attacks, insomnia, anhedonia, concentration problems, memory impairment and suicidal ideation. A meta-analysis found significant association between finasteride use and post-discontinuation depression, suicide ideation, and sexual dysfunction, but the quality of evidence was limited.Plaintiffs have filed over one thousand court cases against Merck over the effects of finasteride. Most were settled by 2018 when Merck paid a lump sum of US$4.3 million to be distributed. As of September 2019, 25 cases remained outstanding in the United States.In 2019 Reuters reported that faulty redactions in court documents revealed allegations from plaintiffs that Merck had known of persistent side effects in their original clinical trials but chose not to disclose them in warning labels. Overdose
Finasteride has been studied in humans at single doses of up to 400 mg and at continuous dosages of up to 80 mg/day for three months, without adverse effects observed. There is no specific recommended antidote for finasteride overdose.
The most probable cause is a low-fiber diet, possibly a result of eating processed food. Diverticulitis is usually seen in about half the American population over the age of 60. Symptoms may include bloating, fever, and nausea. Irritable bowel syndrome, a disorder in the lower intestinal tract, is usually accompanied by other symptoms, such as abdominal pain and diarrhea. It is more common in women and it usually occurs during early adulthood. There are many risk factors such as emotional stress and a low-fiber diet. These can all cause stomach disorders. Nonmedical usage
The word borborygmic has been used in literature to describe noisy plumbing. In Ada, Vladimir Nabokov wrote: "All the toilets and waterpipes in the house had been suddenly seized with borborygmic convulsions". In A Long Way Down (New York: Harper, 1959, p. 54), Elizabeth Fenwick wrote: "The room was very quiet, except for its borborygmic old radiator".Graham Greenes short story "Alas, Poor Maling" tells the tale of a luckless individual whose borborygmus takes the form of irritating noises that he has recently heard. The word borborygmus has also been used in journalism to describe political turbulence. In an article in The Atlantic, Graeme Wood used the word to describe the effects of mass refugee migration into Europe: "Central Europe had to digest a massive refugee flow from Syria and Afghanistan, and the resulting borborygmus upended European politics and enabled a populist wave that has yet to crest." See also
Flatulence
Ileus
Migrating motor complex


== References ==