If indeed this disorder was so common historically, this may point away from modern theories that suggest links between endometriosis and dioxins, PCBs, and chemicals.The early treatment of endometriosis was surgical and included oophorectomy (removal of the ovaries) and hysterectomy (removal of the uterus). In the 1940s, the only available hormonal therapies for endometriosis were high-dose testosterone and high-dose estrogen therapy. High-dose estrogen therapy with diethylstilbestrol for endometriosis was first reported by Karnaky in 1948 and was the main pharmacological treatment for the condition in the early 1950s. Pseudopregnancy (high-dose estrogen–progestogen therapy) for endometriosis was first described by Kistner in the late 1950s. Pseudopregnancy as well as progestogen monotherapy dominated the treatment of endometriosis in the 1960s and 1970s. These agents, although efficacious, were associated with intolerable side effects. Danazol was first described for endometriosis in 1971 and became the main therapy in the 1970s and 1980s. In the 1980s GnRH agonists gained prominence for the treatment of endometriosis and by the 1990s had become the most widely used therapy. Oral GnRH antagonists such as elagolix were introduced for the treatment of endometriosis in 2018. Society and culture
Public figures
A number of public figures have spoken about their experience with endometriosis, including:

Halsey
Emma Bunton
Whoopi Goldberg
Mel Greig
Abby Finkenauer
Julianne Hough
Bridget Hustwaite
Padma Lakshmi
Dolly Parton
Daisy Ridley
Emma Roberts
Kirsten Storms
Chrissy Teigen
Emma Watkins
Danielle Collins
Emma Barnett
Jennifer Boyce - bass player of Ball Park Music

Economic burden
The economic burden of endometriosis is widespread and multifaceted.
Chronic actinic dermatitis is a condition where a subjects skin becomes inflamed due to a reaction to sunlight or artificial light. Patients often have other related conditions of the skin that cause dermatitis in response to a variety of stimuli (e.g., flowers, sunscreens, cosmetics, etc.). Symptoms
Once affected, the symptoms may not show for several days. The symptoms can be severe burning, itching, swelling and pain in the affected areas. The areas exposed to sunlight may have the appearance of a sunburn - where clothing is worn the skin is protected. There is no known reaction to moonlight, but reflections from windows and mirrors of sunlight can still cause damage. Diagnosis
Diagnosis can occur at any age, ranging from soon after birth to adulthood. A GP may refer a patient to a dermatologist if the condition is not showing clear symptoms, and a variety of tests - usually completed at a hospital - can then determine the exact nature and cause of the patients condition. Reactions, which vary depending on the severity of the case, include rashes, flared bumpy patches, affected areas being extremely hot to touch, and outbreaks shortly (or within 24 hours) after direct or indirect exposure to UVA and/or UVB light. The skin most likely reacts on the upper chest, hands and face, however it is not unlikely for reactions to happen all over the body. The patient may feel burning, stinging or throbbing sensations in these areas, which causes mild, yet uncomfortable pain in some patients.