Felbamate interacts with several other AEDs, including phenytoin, valproate, and carbamazepine; dosage adjustments may be necessary to avoid adverse effects. Concomitant administration of felbamate and carbamazepine decreases blood levels of both drugs, while increasing the level of carbamazepine-10,11 epoxide, the active metabolite of carbamazepine. History
Felbamate was discovered by Frank Berger at Wallace Laboratories. References
External links
Felbatol: Prescribing Information
RxList: Felbamate contains extensive information including the patient warning and a sample consent form. Hard Choices with Felbamate
Newer Antiepileptic Drugs: Gabapentin, Lamotrigine, Felbamate, Topiramate and Fosphenytoin
MedPonte Pharmaceuticals
GnRH insensitivity is the second most common cause of IHH, responsible for up to 20% of cases.A minority of less than 5-10% is due to inactivating mutations in genes which positively regulate GnRH secretion such as CHD7, KISS1R, and TACR3.The causes of about 25% of all IHH cases are still unknown. Genetics
Treatment
See also
Hypogonadotropic hypogonadism
Hypergonadotropic hypogonadism
Kallmann syndrome
Genetics of GnRH deficiency conditions
HPG axis
Gonads (testicles and ovaries)
GnRH and gonadotropins (FSH and LH)
Sex hormones (androgens and estrogens)
Fertile eunuch syndrome

References


== External links ==