History
The introduction and use of ampicillin alone started in 1961. The development and introduction of this drug allowed the use of targeted therapies against gram-negative bacteria. With the rise of beta-lactamase producing bacteria, ampicillin and the other penicillin-derivatives became ineffective to these resistant organisms. With the introduction of beta-lactamase inhibitors such as sulbactam, combined with ampicillin made beta-lactamase producing bacteria susceptible. Formulation
Ampicillin-sulbactam only comes in a parenteral formulation to be either used as intravenous or intramuscular injections, and can be formulated for intravenous infusion. It is formulated in a 2:1 ratio of ampicillin:sulbactam. The commercial preparations available include:
1.5 grams (1 gram ampicillin and 0.5 gram sulbactam)→Brand names: Unasyn, Unasyn ADD-Vantage, Unasyn Piggyback

3 grams (2 grams ampicillin and 1 gram sulbactam)→Brand names: Unasyn, Unasyn ADD-Vantage, Unasyn Piggyback

15 grams (10 grams ampicillin and 5 grams sulbactam)→Brand name: Unasyn

Society and culture
Names
Unasyn (US)
Subacillin (Taiwan)
Unictam (Egypt)
Ultracillin (Egypt)
Fortibiotic
Sulbin (Egypt)
Novactam (Egypt)
Sulbacin (Kenya)

References
External links
"Ampicillin mixture with Sulbactam". Drug Information Portal. U.S. National Library of Medicine.
Even with their best criterion, they found dyscalculia diagnoses for children longitudinally did not persist; only 65% of students who were ever diagnosed over the course of four years were diagnosed for at least two years. The percentage of children who were diagnosed in two consecutive years was further reduced. It is unclear whether this was the result of misdiagnosed children improving in mathematics and spatial awareness as they progressed as normal, or that the subjects who showed improvement were accurately diagnosed, but exhibited signs of a non-persistent learning disability. Persistence in adults
There are very few studies of adults with dyscalculia who have had a history of it growing up, but such studies have shown that it can persist into adulthood. It can affect major parts of an adults life. Most adults with dyscalculia have a hard time processing math at a 4th grade level. For 1st-4th grade level, many adults will know what to do for the math problem, but they will often get them wrong because of "careless errors", although they are not careless when it comes to the problem. The adults cannot process their errors on the math problems or may not even recognize that they have made these errors. Visual-spatial input, auditory input, and touch input will be affected due to these processing errors.