Each check-up should incorporate the examination of the patients regional lymph nodes and on a case-by-case basis annual chest X-rays and liver function tests. Spiradenomas
The currently preferred treatment for sporadic SA tumors (including giant vascular eccrine SA) in almost all cases is surgical excision. Many studies recommend wide local surgical excision of these tumors with surgical margins of ≥1 cm in order to ensure that all tumor cells are removed: local lymph node resections are usually reserved for those cases suspected of having lymph node metastases. Mohs micrographic surgery has been used as an alternative to surgical excision for the complete removal of these tumors. Since SA tumors may contain unidentified areas of malignancy and therefore have high recurrence rates, may metastasize to local lymph nodes and/or distant tissues, and can result in overall poor survival times, adjuvant radiation therapy has been used to minimize these aggressive events in SA tumors with equivocal signs of malignancy. However, the effectiveness of these adjuvant therapies has not been established. Adjuvant CO2 laser treatments have been used on occasion to remove these tumors in cases with multiple tumors. Some trials have using botulinum toxin A and triamcinolone injections directly into SA tumors but these trials have had limited success. Spiradenocarcinomas
With only 117 malignant cases reported in the literature as of 2022, there are no standard guidelines for the treatment of SAC tumors. Localized (i.e.
Novolin is the brand name of three distinct insulin-containing products manufactured by Novo Nordisk:

Novolin 70/30, an insulin preparation containing mixed NPH and regular insulin, respectively
Novolin N, an insulin preparation containing NPH insulin
Novolin R, an insulin preparation containing regular insulin

See also
Insulin (medication)


== References ==