Mohr–Tranebjærg syndrome (MTS) is a rare X-linked recessive syndrome also known as deafness–dystonia syndrome and caused by mutation in the TIMM8A gene. It is characterized by clinical manifestations commencing with early childhood onset hearing loss, followed by adolescent onset progressive dystonia or ataxia, visual impairment from early adulthood onwards and dementia from the 4th decade onwards. The severity of the symptoms may vary, but they progress usually to severe deafness and dystonia and sometimes are accompanied by cortical deterioration of vision and mental deterioration. Signs and Symptoms
Mohr-Tranebjærg is characterized by a variety of symptoms affecting hearing loss. In the span of a subject with Mohr-Tranebjærg, by the age of early childhood, around 18 months, the development of quickly progressive prelingual or postlingual sensorineural hearing loss. The presence of auditory symptoms is characterized by preserved oto-acoustic emissions, abnormal auditory brain stem response, poor speech, and worsening in auditory symptoms even with auditory devices. Also, neuropsychological manifestations, possibly consisting of personality changes, paranoia, and mild intellectual deficit could emerge. During adolescence, there is a possibility that a slowly progressive movement disorder, similar to gegenhalten, dystonia, or ataxia could develop. Patients with Mohr-Tranebjærg experience reduced visual acuity, photophobia, acquired color vision defect and central scotomas developing at around 20 years of age, and leading to more severe blindness by age 30 or 40.The first symptom of DDON syndrome is hearing loss caused by nerve damage in the inner ear (sensorineural hearing loss), which begins in early childhood.
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Archaeological site
Campsite, a place used for overnight stay in an outdoor area
Construction site
Location, a point or an area on the Earths surface or elsewhere
Website, a set of related web pages, typically with a common domain nameIt may also refer to:

Site, a National Register of Historic Places property type
SITE (originally known as Sculpture in the Environment), an American architecture and design firm
Site (mathematics), a category C together with a Grothendieck topology on C
The Site, a 1990s TV series that aired on MSNBC
SITE Intelligence Group, a for-profit organization tracking jihadist and white supremacist organizations
SITE Institute, a terrorism-tracking organization, precursor to the SITE Intelligence Group
Sindh Industrial and Trading Estate, a company in Sindh, Pakistan
SITE Centers, American commercial real estate company
SITE Town, a densely populated town in Karachi, Pakistan
S.I.T.E Industrial Area, an area in Karachi, Pakistan
Satellite Instructional Television Experiment, an experimental satellite communications project launched in India in 1975
Google Sites, web based website editor

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Sites, California
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