Accurate details in Wilders novel include the blizzards frequency and the deep cold, the Chicago and North Western Railway stopping trains until the spring thaw because the snow made the tracks impassable, the near-starvation of the townspeople, and the courage of her future husband Almanzo and another man, who ventured out on the open prairie in search of a cache of wheat that no one was even sure existed. The October blizzard brought snowfalls so deep that two-story homes had snow up to the second floor windows. No one was prepared for the deep snow so early in the season and farmers all over the region were caught before their crops had even been harvested, their grain milled, or with their fuel supplies for the winter in place. By January the train service was almost entirely suspended from the region. Railroads hired scores of men to dig out the tracks but it was a wasted effort: As soon as they had finished shoveling a stretch of line, a new storm arrived, filling up the line and leaving their work useless. There were no winter thaws and on February 2, 1881, a second massive blizzard struck that lasted for nine days. In the towns the streets were filled with solid drifts to the tops of the buildings and tunneling was needed to secure passage about town. Homes and barns were completely covered, compelling farmers to tunnel to reach and feed their stock.
Early medical abortion regimens using mifepristone, followed 24–48 hours later by buccal or vaginal misoprostol are 98% effective up to 9 weeks gestational age; from 9 to 10 weeks efficacy decreases modestly to 94%. If medical abortion fails, surgical abortion must be used to complete the procedure.Early medical abortions account for the majority of abortions before 9 weeks gestation in Britain, France, Switzerland, United States, and the Nordic countries.Medical abortion regimens using mifepristone in combination with a prostaglandin analog are the most common methods used for second-trimester abortions in Canada, most of Europe, China and India, in contrast to the United States where 96% of second-trimester abortions are performed surgically by dilation and evacuation.A 2020 Cochrane Systematic Review concluded that providing women with medications to take home to complete the second stage of the procedure for an early medical abortion results in an effective abortion. Further research is required to determine if self-administered medical abortion is as safe as provider-administered medical abortion, where a health care professional is present to help manage the medical abortion. Safely permitting women to self-administer abortion medication has the potential to improve access to abortion. Other research gaps that were identified include how to best support women who choose to take the medication home for a self-administered abortion. Surgical
Up to 15 weeks gestation, suction-aspiration or vacuum aspiration are the most common surgical methods of induced abortion.