The emperor also goes further than Orion by attributing eunuchs lack of male-female intercourse specifically to castration, which he said was performed with the intention "that they will no longer do the things that males do, or at least to extinguish whatever has to do with desire for the female sex". The 11th century Byzantine monk Nikon of the Black Mountain, opting instead for Orions second alternative, stated that the word came from eunoein (eu "good" + nous "mind"), thus meaning "to be well-minded, well-inclined, well-disposed or favorable", but unlike Orion he argued that this was due to the trust that certain jealous and suspicious foreign rulers placed in the loyalty of their eunuchized servants. Theophylact of Ohrid in a dialogue In Defence of Eunuchs also stated that the origin of the word was from eupnoeic and ekhein, "to have, hold", since they were always "well-disposed" toward the master who "held" or owned them. The 12th century Etymologicum Magnum (s.v. eunoukhos) essentially repeats the entry from Orion, but stands by the first option, while attributing the second option to what "some say". In the late 12th century, Eustathius of Thessalonica (Commentaries on Homer 1256.30, 1643.16) offered an original derivation of the word from eunis + okheuein, "deprived of mating".
First millennium BCE
Mutakkil-Marduk (8th century BCE): Assyrian chief eunuch, eponym of the year 798 BCE in an Assyrian eponym chronicle. Yariri (8th century BCE): regent of Neo-Hittite Carchemish thought likely to be a eunuch. Sin-shumu-lishir (7th century BCE): Assyrian eunuch who attempted to usurp power in the Neo-Assyrian Empire. Aspamistres or Mithridates (5th century BCE): bodyguard of Xerxes I of Persia, and (with Artabanus) his murderer. Artoxares: an envoy of Artaxerxes I and Darius II of Persia. Bagoas (4th century BCE): prime minister of king Artaxerxes III of Persia, and his assassin (Bagoas is an old Persian word meaning eunuch). Bagoas (4th century BCE): a favorite of Alexander the Great. Influential in changing Alexanders attitude toward Persians and therefore in the kings policy decision to try to integrate the conquered peoples fully into his Empire as loyal subjects. He thereby paved the way for the relative success of Alexanders Seleucid successors and greatly enhanced the diffusion of Greek culture to the East. Batis (4th century BCE): resisted Alexander the Great at the Siege of Gaza. Philetaerus (4th/3rd century BCE): founder of the Attalid dynasty of Pergamum
Zhao Gao (died 210 BCE): favourite of Qin Shihuangdi, who plotted against Li Si. Sima Qian (old romanization Ssu-ma Chien; 2nd/1st century BCE): the first person to have practiced modern historiography – gathering and analyzing both primary and secondary sources to write his monumental history of the Chinese Empire. Ganymedes (1st century BCE): highly capable adviser and general of Cleopatra VIIs sister and rival, Princess Arsinoe.