The overall mortality rate from HUS is 5–15%. Children and the elderly have a worse prognosis.Patients with aHUS generally have poor outcomes, with up to 50% progressing to end-stage renal disease (ESRD) or irreversible brain damage; as many as 25% die during the acute phase. Epidemiology
The country with the highest incidence of HUS is Argentina and it performs a key role in the research of this condition. In the United States, the overall incidence of HUS is estimated at 2.1 cases per 100,000 persons/year, with a peak incidence between six months and four years of age.HUS and the E. coli infections that cause it have been the source of much negative publicity for the FDA, meat industries, and fast-food restaurants since the 1990s, especially in the contaminations linked to Jack in the Box restaurants. In 2006, an epidemic of harmful E. coli emerged in the United States due to contaminated spinach. In June, 2009, Nestlé Toll House cookie dough was linked to an outbreak of E. coli O157:H7 in the United States, which sickened 70 people in 30 states.In May, 2011 an epidemic of bloody diarrhea caused by E. coli O104:H4-contaminated fenugreek seeds hit Germany. Tracing the epidemic revealed more than 3,800 cases, with HUS developing in more than 800 of the cases, including 36 fatal cases. Nearly 90% of the HUS cases were in adults. References
External links
GeneReviews/NCBI/NIH/UW entry on Atypical hemolytic–uremic syndrome
Symptoms
Dust mite allergy symptoms include:

Cough
Facial pressure and pain
Itchy, red or watery eyes
Itchy nose, roof of the mouth or throat
Nasal congestion
Postnasal drip
Runny nose, sneezing
Swollen, blue-colored skin under the eyesIf the dust mite allergy contributes to asthma:

Audible whistling or wheezing sound when exhaling
Bouts of coughing or wheezing that are worsened by a respiratory virus such as a cold or the flu
Chest tightness or pain
Difficulty breathing
Trouble sleeping caused by shortness of breath, coughing or wheezing

Cross-reactivity to shellfish allergy
Tropomyosin, the major allergen in dust mites, is also responsible for shellfish allergy. Exposure to inhaled tropomyosins from dust mites is thought to be the primary sensitizer for shellfish allergy, an example of inhalant-to-food cross-reactivity. Epidemiological surveys have confirmed correlation between shellfish and dust mite sensitizations. An additional confirmation was seen in Orthodox Jews with no history of shellfish consumption, in that skin tests confirming dust mite allergy were also positive for shellfish tropomyosin. In addition to tropomyosin, the proteins arginine kinase and hemocyanin seem to have a role in cross-reactivity to dust mites. Prevention
House dust mites are present indoors wherever humans live. Positive tests for dust mite allergies are extremely common among people with asthma. Dust mites are microscopic arachnids whose primary food is dead human skin cells, but they do not live on living people. They and their feces and other allergens that they produce are major constituents of house dust, but because they are so heavy they are not suspended for long in the air.