This is down from 27 cases in 2020, and dramatically less than the estimated 3.5 million annual cases in 20 countries in 1986 – the year the World Health Assembly called for dracunculiasis eradication. Dracunculiasis remains endemic in just four countries: Chad, Ethiopia, Mali, and South Sudan.Dracunculiasis is a disease of extreme poverty, occurring in places where there is poor access to clean drinking water. Cases tend to be split roughly equally between males and females, and can occur in all age groups. Within a given place, dracunculiasis risk is linked to occupation; people who farm or fetch drinking water are most likely to be infected.Cases of dracunculiasis have a seasonal cycle, though the timing varies by location. Along the Sahara deserts southern edge, cases peak during the mid-year rainy season (May–October) when stagnant water sources are more abundant. Along the Gulf of Guinea, cases are more common during the dry season (October–March) when flowing water sources dry up. History
Dracunculiasis has been with humans for at least 3,000 years, as the remnants of a guinea worm infection have been found in the mummy of a girl entombed in Egypt around 1,000 BCE. Diseases consistent with the effects of dracunculiasis are referenced by writers throughout antiquity. The disease of "fiery serpents" that plagues the Hebrews in the Old Testament (around 1250 BCE) is often attributed to dracunculiasis.
Functionally, the subcutaneous fat insulates the body, absorbs trauma, and serves as a reserve energy source. Diseases of the skin
Diseases of the skin include skin infections and skin neoplasms (including skin cancer). History
In 1572, Geronimo Mercuriali of Forlì, Italy, completed De morbis cutaneis (On the diseases of the skin). It is considered the first scientific work dedicated to dermatology. Diagnoses
The physical examination of the skin and its appendages, as well as the mucous membranes, forms the cornerstone of an accurate diagnosis of cutaneous conditions. Most of these conditions present with cutaneous surface changes termed "lesions," which have more or less distinct characteristics. Often proper examination will lead the physician to obtain appropriate historical information and/or laboratory tests that are able to confirm the diagnosis. Upon examination, the important clinical observations are the (1) morphology, (2) configuration, and (3) distribution of the lesion(s). With regard to morphology, the initial lesion that characterizes a condition is known as the "primary lesion", and identification of such a lesions is the most important aspect of the cutaneous examination. Over time, these primary lesions may continue to develop or be modified by regression or trauma, producing "secondary lesions". However, with that being stated, the lack of standardization of basic dermatologic terminology has been one of the principal barriers to successful communication among physicians in describing cutaneous findings. Nevertheless, there are some commonly accepted terms used to describe the macroscopic morphology, configuration, and distribution of skin lesions, which are listed below.