Some cases have been reported that the anemia is reversed or heme level is improved through use of moderate to high doses of pyridoxine (vitamin B6). In severe cases of SBA, bone marrow transplant is also an option with limited information about the success rate. Some cases are listed on MedLine and various other medical sites. In the case of isoniazid-induced sideroblastic anemia, the addition of B6 is sufficient to correct the anemia. Deferoxamine, a chelating agent, is used to treat iron overload from transfusions. Therapeutic phlebotomy can be used to manage iron overload. Prognosis
Sideroblastic anemias are often described as responsive or non-responsive in terms of increased hemoglobin levels to pharmacological doses of vitamin B6.1- Congenital: 80% are responsive, though the anemia does not completely resolve. 2- Acquired clonal: 40% are responsive, but the response may be minimal. 3- Acquired reversible: 60% are responsive, but course depends on treatment of the underlying cause. Severe refractory sideroblastic anemias requiring regular transfusions and/or that undergo leukemic transformation (5–10%) significantly reduce life expectancy. See also
Anemia
Siderosis
List of hematologic conditions
Hematopoietic stem cell transplantation

References
External links

GeneReviews/NCBI/NIH/UW entry on X-Linked Sideroblastic Anemia and Ataxia
Foot immersion is a common problem with homeless individuals wearing one pair of socks and shoes for extensive periods of time, especially wet shoes and sneakers from rain and snow. The condition is exacerbated by excessive dampness of the feet for prolonged periods of time. Fungus and bacterial infections prosper in the warm, dark, wet conditions and are characterized by a sickly odor that is distinct to foot immersion. : 27

Prevention
In the British Army, policies were developed to help the soldiers keep their feet dry — the surest way of preventing the disease. Soldiers were told to dry their feet, and keep them dry by changing socks several times a day. After the first year of the First World War, British troops were instructed to keep at least three pairs of socks with them and to frequently change them. The use of whale oil was also successful in combating trench foot. A British battalion in front line positions could be expected to use ten gallons of whale oil every day. References


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