The muscle cell may also be disorganized because the aggregates may interrupt other filament structures and/or normal cellular function.Desminopathies are very rare diseases and As of 2004 only 60 patients have been diagnosed, however this number probably does not accurately represent the population due to frequent mis or under diagnosis. Diagnosis
Desminopathies are diagnosed by genetic analysis. Because mutations in several further genes might be pathogenic for skeletal and cardiac myopathies, gene panels or whole exome sequence analysis are mostly used. Sanger sequencing is consequently used to verify NGS-data. Treatment
There is currently no cure for the disease but treatments to help the symptoms are available. Prognosis
Prognosis strongly depends on which subtype of disease it is. Some are deadly in infancy but most are late onset and mostly manageable. References


== External links ==
U.S. National Library of Medicine. Emergency Use Authorization (EUA) review for bamlanivimab
Emergency Use Authorization (EUA) for bamlanivimab/etesevimab
Frequently Asked Questions on the Emergency Use Authorization for bamlanivimab and etesevimab