The tapeworm from undercooked fish (Diphyllobothrium latum) absorbs huge quantities of vitamin B12, and infested patients often have associated gastric atrophy. The blind loop syndrome may produce deficiency of vitamin B12 or folate. Inadequate use of vitamin B12, which may occur if antimetabolites for the vitamin are employed in the treatment of neoplasiaPernicious anemia is the most common cause of vitamin B12 deficiency. While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B12-deficient anemia as a whole, regardless of cause. Side effects
The literature data on the acute toxicity profile of hydroxocobalamin show it is generally regarded as safe with local and systemic exposure. The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure. The US FDA at the end of 2006 approved the use hydroxocobalamin as an injection for the treatment of cyanide poisoning. The drug causes a reddish discoloration of the urine (chromaturia), which can look like blood in the urine. Properties
Hydroxocobalamin acetate occurs as odorless, dark-red orthorhombic crystals. The injection formulations appear as clear, dark-red solutions. It has a distribution coefficient of 1.133 × 10-5 and a pKa of 7.65. Mechanism of action
Vitamin B12 refers to a group of compounds called cobalamins that are available in the human body in a variety of mostly interconvertible forms.
Koro may refer to:

Geography
Koro Island, a Fijian island
Koro Sea, in the Pacific Ocean
Koro, Ivory Coast
Koro, Mali
Koro, Wisconsin, United States, an unincorporated community

Languages
Koro language (India), an endangered language spoken in Arunachal Pradesh, India
Koro language (New Guinea)
Koro language (Vanuatu)
Koro, a variety of the Maninka language spoken in Ivory Coast

Polynesian culture
Oro, a god in Polynesian mythology
Koro (literally, "grandfather"), a term of respect in the Māori language for a male Kaumātua (tribal elder)

Other uses
Kōrō, a masculine Japanese given name
KORO, a Spanish-language television station in Corpus Christi, Texas, USA
Koro (incense burner), a Japanese incense burner
Koro (medicine), the syndrome in which someone believes their external genitals are retracting
Koro Wachi language, spoken in Nigeria
Musiliu Obanikoro, popularly known as Koro
Nkoroo language, Nigeria