Well more cases have been reported when used in combination  with sorbitol and other cases have occurred when used alone. Interactions
Polystyrene sulfonates can bind to various drugs within the digestive tract and thus lower their absorption and effectiveness. Common examples include lithium, thyroxine, and digitalis. In September 2017, the FDA recommended separating the dosing of polystyrene sulfonate from any other oral medications by at least three hours to avoid any potential interactions. Mechanism of action
Hyperkalemia
Polystyrene sulfonates release sodium or calcium ions in the stomach in exchange for hydrogen ions. When the resin reaches the large intestine the hydrogen ions are exchanged for free potassium ions; the resin is then eliminated in the feces. The net effect is lowering the amount of potassium available for absorption into the blood and increasing the amount that is excreted via the feces. The effect is a reduction of potassium levels in the body, at a capacity of 1 mEq of potassium exchanged per 1 g of resin. Production and chemical structure
Polystyrene sulfonic acid, the acid whose salts are the polystyrene sulfonates, has the idealized formula (CH2CHC6H4SO3H)n.  The material is prepared by sulfonation of polystyrene:

(CH2CHC6H5)n  +  n SO3   →   (CH2CHC6H4SO3H)nSeveral methods exist for this conversion, which can lead to varying degree of sulfonation. Usually the polystyrene is crosslinked, which keeps the polymer from dissolving. Since the sulfonic acid group (SO3H) is strongly acidic, this polymer neutralizes bases.
Panophthalmitis is the inflammation of all coats of the animal eye including intraocular structures. It can be caused by infection, particularly from Pseudomonas species, such as Pseudomonas aeruginosa, Clostridium species, Whipples disease, and also fungi. It can also be cause by other stress. References
Further reading
Font, R. L. (1967). "Endogenous Mycotic Panophthalmitis Caused by Blastomyces dermatitidis". Archives of Ophthalmology. 77 (2): 217–22. doi:10.1001/archopht.1967.00980020219012. ISSN 0003-9950. PMID 6019015. Chawla, Rohan, et al. "Case report of tuberculous panophthalmitis." Medical Science Monitor 10.10 (2004): CS57-CS59. == External links ==