In children who are aged greater than 48 hours, serum glucose on average ranges from 70 to 100 mg/dL (3.9-5.5 mmol/L), similar to adults, with hypoglycemia being far less common. Diagnostic approach
The most reliable method of identifying hypoglycemia is through identifying Whipples triad. The components of Whipples triad are a blood sugar level below 70 mg/dL (3.9 mmol/L), symptoms related to low blood sugar, and improvement of symptoms when blood sugar is restored to normal. Identifying Whipples triad in a patient helps to avoid unnecessary diagnostic testing and decreases healthcare costs.In those with a history of diabetes treated with insulin, glinides, or sulfonylurea, who demonstrate Whipples triad, it is reasonable to assume the cause of hypoglycemia is due to insulin, glinides, or sulfonylurea use. In those without a history of diabetes with hypoglycemia, further diagnostic testing is necessary to identify the cause. Testing, during an episode of hypoglycemia, should include the following:

Plasma glucose level, not point-of-care measurement
Insulin level
C-peptide level
Proinsulin level
Beta-hydroxybutyrate level
Oral hypoglycemic agent screen
Response of blood glucose level to glucagon
Insulin antibodiesIf necessary, a diagnostic hypoglycemic episode can be produced in an inpatient or outpatient setting. This is called a diagnostic fast, in which a patient undergoes an observed fast to cause a hypoglyemic episode, allowing for appropriate blood work to be drawn.
Notable persons
John Belluso, writer for the CBS television show Ghost Whisperer, used a wheel chair from the age of 13 because of the Camurati–Engelmann syndrome. He died on February 10, 2006, at the age of 36 in New York City. References
Further reading
Camurati-Engelmann disease on Genetic Home Reference
GeneReviews/NCBI/NIH/UW entry on Camurati-Engelmann Disease
Wallace, Stephanie E.; Wilcox, William R. (1 January 1993). Camurati-Engelmann Disease. GeneReviews. University of Washington, Seattle. PMID 20301335. == External links ==