In contrast, increasing rates of obesity at a societal level are felt to be due to an easily accessible and palatable diet, increased reliance on cars, and mechanized manufacturing.A 2006 review identified ten other possible contributors to the recent increase of obesity: (1) insufficient sleep, (2) endocrine disruptors (environmental pollutants that interfere with lipid metabolism), (3) decreased variability in ambient temperature, (4) decreased rates of smoking, because smoking suppresses appetite, (5) increased use of medications that can cause weight gain (e.g., atypical antipsychotics), (6) proportional increases in ethnic and age groups that tend to be heavier, (7) pregnancy at a later age (which may cause susceptibility to obesity in children), (8) epigenetic risk factors passed on generationally, (9) natural selection for higher BMI, and (10) assortative mating leading to increased concentration of obesity risk factors (this would increase the number of obese people by increasing population variance in weight). According to the Endocrine Society, there is "growing evidence suggesting that obesity is a disorder of the energy homeostasis system, rather than simply arising from the passive accumulation of excess weight". Diet
A 2016 review supported excess appetite for palatable, high-calorie food (especially fat, sugar, and certain animal proteins) as the primary factor driving obesity worldwide, likely because of imbalances in neurotransmitters affecting the drive to eat. Dietary energy supply per capita varies markedly between different regions and countries. It has also changed significantly over time.
Proctocolitis is a general term for inflammation of the rectum and colon. Signs and symptoms
Cause
Proctocolitis has many possible causes. Common infectious causes of proctocolitis include Chlamydia trachomatis, LGV (Lymphogranuloma venereum), Neisseria gonorrhoeae, HSV, and Helicobacter species. It can also be idiopathic (see colitis), vascular (as in ischemic colitis), or autoimmune (as in inflammatory bowel disease). Diagnosis
Anoscopy can be used to diagnose the majority of cases of proctocolitis. Treatment
Antibiotics, such as ceftriaxone and doxycycline, if there is  infection

See also
Colitis
Proctitis

References


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