It is typically taken for one to two weeks before entering an area with malaria. Doxycycline and atovaquone/proguanil provide protection within one to two days and may be better tolerated. If a person becomes ill with malaria despite prophylaxis with mefloquine, the use of halofantrine and quinine for treatment may be ineffective. : 4

Malaria treatment
Mefloquine is used as a treatment for chloroquine-sensitive or resistant Plasmodium falciparum malaria, and is deemed a reasonable alternative for uncomplicated chloroquine-resistant Plasmodium vivax malaria. It is one of several drugs recommended by the United States Centers for Disease Control and Prevention. It is not recommended for severe malaria infections, particularly infections from P. falciparum, which should be treated with intravenous antimalarials. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with P. vivax malaria should be treated with a second drug that is effective for the liver phase, such as primaquine. : 4

Resistance to mefloquine
Resistance to mefloquine is common around the west border in Cambodia and other parts of Southeast Asia. The mechanism of resistance is by increase in Pfmdr1 copy number. Adverse effects
Common side effects include vomiting, diarrhea, headaches, and a rash. Severe side effects requiring hospitalization are rare, but include mental health problems such as depression, hallucinations, anxiety and neurological side effects such as poor balance, seizures, and ringing in the ears. Mefloquine is therefore not recommended in people with a history of psychiatric disorders or epilepsy.
A man committing the offence of voyeurism would be liable for imprisonment not less than one year and which may extend up to three years for the first offence, and shall also be liable to fine and for any subsequent conviction would be liable for imprisonment for not less than three years and which may extend up to seven years and with fine. Voyeurism is generally deemed illegal in Singapore. It sentences technologically-enabled voyeurs to a maximum punishment of one years jail and a fine under the context of insulting a womans modesty. Recent cases in 2016 include the sentencing of church facility manager Kenneth Yeo Jia Chuan who filmed women in toilets by planting pinhole cameras in a handicapped toilet at the Church of Singapore at Bukit Timah, and in the unisex toilet of the churchs office at Bukit Timah Shopping Centre.Secret photography by law enforcement authorities is called surveillance and is not considered to be voyeurism, though it may be unlawful or regulated in some countries. Popular culture
Films
Voyeurism is a main theme in films such as The Secret Cinema (1968), Peepers (2010), and Sliver (1993), based on a book of the same name by Ira Levin.