Frequent colon cleansing can lead to dependence on enemas to defecate and some herbs may reduce the effectiveness of, or increase the risks associated with the use of prescription medications. Effectiveness and risks
The symptoms that are attributed to autointoxication—headache, fatigue, loss of appetite and irritability—may be caused by mechanical distention within the bowel, such as irritable bowel syndrome, rather than toxins from putrefying food. The benefits anecdotally attributed to colon cleansing are vague and the claims made by manufacturers and practitioners are based on a flawed understanding of the body. There is little evidence of actual benefit to the procedure, and no evidence that it can alleviate the symptoms that are attributed to the theories of colon cleansing.As the colon normally expels waste, colon cleansing is generally unneeded. Colonic irrigation can disrupt the bowels normal flora, and, if done frequently, can result in electrolyte depletion with dehydration. Rare but severe adverse events have been rectal perforation, as well as amoebic infection, from poorly sterilised equipment. Others claim that colon cleansing may impede the colons shedding of dead cells.Excessive use of enemas has also been associated with heart problems, such as heart failure, as well as heart attacks related to electrolyte imbalances when performed as a coffee enema. Frequent enemas or other colon-cleansing tools may lead to dependence and inability to defecate without assistance, as well as potential withdrawal symptoms. Herbs taken orally may modulate the absorption or the activity of prescription medications.Medical doctor Harriet Hall writes that "The colon cleanses itself...
Ribavirin, also known as tribavirin, is an antiviral medication used to treat RSV infection, hepatitis C and some viral hemorrhagic fevers. For hepatitis C, it is used in combination with other medications such as simeprevir, sofosbuvir, peginterferon alfa-2b or peginterferon alfa-2a. Among the viral hemorrhagic fevers it is used for Lassa fever, Crimean–Congo hemorrhagic fever, and Hantavirus infection but should not be used for Ebola or Marburg infections. Ribavirin is taken by mouth or inhaled.Common side effects include feeling tired, headache, nausea, fever, muscle pains, and an irritable mood. Serious side effects include red blood cell breakdown, liver problems, and allergic reactions. Use during pregnancy results in harm to the baby. Effective birth control is recommended for both males and females for at least seven months during and after use. The mechanism of action of ribavirin is not entirely clear.Ribavirin was patented in 1971 and approved for medical use in 1986. It is on the World Health Organizations List of Essential Medicines. It is available as a generic medication. Medical uses
Ribavirin is used primarily to treat hepatitis C and viral hemorrhagic fevers (which is an orphan indication in most countries). In this former indication the oral (capsule or tablet) form of ribavirin is used in combination with pegylated interferon alfa, including in people coinfected with hepatitis B, HIV and in the pediatric population.