If this occurs, individuals usually undergo a more intensive medication regimen than what was originally given to them. Immune checkpoint inhibitors
New treatment options designed to reduce the risk of resistance are currently being researched, such as immune checkpoint inhibitors. Studies of gestational choriocarcinoma demonstrate an increased expression of the ligand PD-L1 and its corresponding receptor PD-1, leading to drug research and development into medications that can block the PD-1 receptor, such as Pembrolizumab. In individuals requiring more intensive chemotherapy options, using an immune checkpoint inhibitor may be preferable to long-term use of multi-agent chemotherapy to prevent prolonged toxicity to the body. Prognosis
The survival rate following treatment with chemotherapy is approximately at least 90%. If gestational choriocarcinoma has spread to the liver in an individual, survival rate may be lower. Overall survival rate is also higher when management of gestational choriocarcinoma occurs in a setting with physicians familiar with the condition. Earlier diagnosis and treatment intervention can lead to greater success in preserving potential of future pregnancy in those seeking it.Return of human chorionic gonadotropic levels to within the bounds of normal values lowers the chance of recurring gestational choriocarcinoma. These levels can be checked monthly as follow-up. If an individual is interested in pregnancy following chemotherapy treatment for gestational choriocarcinoma, it is recommended that they wait a minimum of one year following chemotherapy before they plan to have a child to minimize the chance of miscarriage. == References ==
Triangular alopecia  is hair loss that may be congenital but usually appears in childhood as a focal patch of loss that may be complete or leaving fine vellus hairs behind. : 643  Affected individuals are typically entirely healthy. Hair restoration surgery using follicular unit transplantation has been a successful treatment modality for TTA

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Association with Other Conditions
TTA has been associated with several disorders, such as Phakomatosis pigmentovascularis. And a rare syndrome Setleis syndrome. It is inherited by the autosomal dominant trait and is characterized by cutis aplasia or atrophic skin at the temples, which is said to resemble forceps marks. There may also be a coarse facial appearance, anomalies of the eyelashes and eyebrows, and periorbital puffiness. Frequency
The suggested frequency for this condition in the general population is around 0.11%. The hair loss is non-progressive and does not expand beyond these areas. It is a non-inflammatory, non-scarring form of hair loss easily confused with alopecia areata. In one report, the condition was incorrectly believed by the parents to be induced by doctors inserting intravenous cannulas into scalp vessels during the neonatal period. The condition is permanent and the affected skin does not change later in life.Of the 53 reported cases of TTA, more than half (55.8%) were detected in childhood between the ages of 2 and 9 years, while 36.5% were detected at birth and only 3.8% (only two cases) in adulthood. See also
Alopecia
Skin lesion
List of cutaneous conditions


== References ==