In medicine (hematology), bleeding diathesis  is an unusual susceptibility to bleed (hemorrhage) mostly due to hypocoagulability (a condition of irregular and slow blood clotting), in turn caused by a coagulopathy (a defect in the system of coagulation). Therefore, this may result in the reduction of platelets being produced and leads to excessive bleeding. Several types of coagulopathy are distinguished, ranging from mild to lethal. Coagulopathy can be caused by thinning of the skin (Cushings syndrome), such that the skin is weakened and is bruised easily and frequently without any trauma or injury to the body. Also, coagulopathy can be contributed by impaired wound healing or impaired clot formation. Signs and symptoms
Complications
Following are some complications of coagulopathies, some of them caused by their treatments:

Causes
While there are several possible causes, they generally result in excessive bleeding and a lack of clotting. Acquired
Acquired causes of coagulopathy include anticoagulation with warfarin, liver failure, vitamin K deficiency and disseminated intravascular coagulation. Additionally, the hemotoxic venom from certain species of snakes can cause this condition, for example Bothrops, rattlesnakes and other species of viper. Viral hemorrhagic fevers include dengue hemorrhagic fever and dengue shock syndrome. Leukemia may also cause coagulopathy. Furthermore, cystic fibrosis has been known to cause bleeding diathesis, especially in undiagnosed infants, due to malabsorption of fat soluble vitamins like vitamin K.

Autoimmune causes of acquired coagulation disorders
There are autoimmune causes of coagulation disorders. They include acquired antibodies to coagulation factors, termed inhibitors of coagulation. The main inhibitor is directed against clotting factor VIII.
Polysyndactyly is a hereditary anatomical malformation combining polydactyly and syndactyly. There is also a type called crossed polysyndactyly. Signs and symptoms
The way polysyndactyly presents itself varies; when the webbing is mild, it gives the appearance of the extra digit being partially connected to the (otherwise normal) digit next to it, when the webbing is extreme, the extra digit and the digit next to it will have the appearance of one rather enlarged digit (macrodactyly) and will have two or more finger/toe nails growing in the same digit (polyonychia). How the nails look will also vary, from separate supernumerary finger/toe nails to one very wide finger/toe nail. References
External links
Polysyndactyly and Marfans syndrome The case of an Egyptian Jewish family with 17 affected members. The mother also had Marfans syndrome, which she passed on to a daughter who did not have polysyndactyly.