The cellular function that links them is a common signalling pathway that brings information from outside the cell to the nucleus. This pathway is called the Ras-MAP-kinase signal transduction pathway (Ras-MAPK Pathway). References
Some text in this article was originally taken from http://ghr.nlm.nih.gov/condition=costellosyndrome, a public domain source

External links

GeneReviews: Costello Syndrome
GeneReviews: Daisys battle with Costello Syndrome
The underlying causes of the condition, such as over-prescription of anticoagulants, must be addressed as well so that the hemopericardium does not return.While hemopericardium itself is not fatal, it may lead to cardiac tamponade, which can be deadly if not treated promptly. One study found that cardiac tamponade was fatal in 13.3% of cases in which it was not caused by a malignant disease. Research
Studies have shown that hemopericardium can occur spontaneously in people with essential thrombocythemia, although this is relatively rare. It is a more common occurrence in patients who have been over-prescribed anticoagulants. Regardless of the underlying cause of the hemopericardium, pericardiocentesis has shown to be the best treatment method for the condition. References


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