While coprological diagnosis of fasciolosis is possible from 8- to 12-week post-infection (WPI), F. hepatica specific-antibodies are recognized using ELISA or Western blot after 2-4 week post-infection. Therefore, these methods provide early detection of the infection. Prevention
In some areas special control programs are in place or have been planned. The types of control measures depend on the setting (such as epidemiologic, ecologic, and cultural factors). Strict control of the growth and sale of watercress and other edible water plants is important. Individual people can protect themselves by not eating raw watercress and other water plants, especially from endemic grazing areas. Travelers to areas with poor sanitation should avoid food and water that might be contaminated (tainted). Vegetables grown in fields, that might have been irrigated with polluted water, should be thoroughly cooked, as should viscera from potentially infected animals. Treatment
Humans
Several drugs are effective for fascioliasis, both in humans and in domestic animals. The drug of choice in the treatment of fasciolosis is triclabendazole, a member of the benzimidazole family of anthelmintics. The drug works by preventing the polymerization of the molecule tubulin into the cytoskeletal structures, microtubules. Resistance of F. hepatica to triclabendazole has been recorded in Australia in 1995 and Ireland in 1998.Praziquantel treatment is ineffective. There are case reports of nitazoxanide being successfully used in human fasciolosis treatment in Mexico. There are also reports of bithionol being used successfully.Nitazoxanide has been found effective in trials, but is currently not recommended.
Countries where fasciolosis in livestock was repeatedly reported:
Europe: UK, Ireland, France, Portugal, Spain, Switzerland, Italy, Netherlands, Germany, Poland
Asia: Turkey, Russia, Thailand, Iraq, Iran, China, Vietnam, India, Nepal, Japan, Korea, Philippines
Africa: Kenya, Zimbabwe, Nigeria, Egypt, Gambia, Morocco
Australia and the Oceania: Australia, New Zealand
Americas: United States, Mexico, Cuba, Peru, Chile, Uruguay, Argentina, Jamaica, BrazilOn September 8, 2007, Veterinary officials in South Cotabato, Philippines said that laboratory tests on samples from cows, carabaos, and horses in the provinces 10 towns and lone city showed the level of infection at 89.5%, a sudden increase of positive cases among large livestock due to the erratic weather condition in the area. They must be treated forthwith to prevent complications with surra and hemorrhagic septicemia diseases. Surra already affected all barangays of the Surallah town. See also
Fasciolopsiasis
Clonorchiasis
Fh8 - chemical produced by fasciolosis infection in the liver

References
External links

Fasciolosis Overview Archived 2008-02-04 at the Wayback Machine at CDC
Immunodiagnosis of fasciolosis in Bolivian Altiplano
Fasciolosis Archived 2009-03-10 at the Wayback Machine
Pictures of adult flukes
Pictures of F. hepatica eggs