Medications do not help retrograde ejaculation if there has been permanent damage to the prostate or the testes from radiation. Medications also do not help if prostate surgery has resulted in damage to the muscles or nerves. Medications only work if there has been mild nerve damage caused by diabetes, multiple sclerosis, or mild spinal cord injury. Medications
Tricyclic antidepressants like imipramine. Antihistamines like chlorphenamine. Decongestants like ephedrine and phenylephrine.These medications tighten the bladder neck muscles and prevent semen from going backwards into the bladder. However, the medications do have many side effects and they have to be taken at least 1–2 hours prior to sexual intercourse. In many cases, the medications fail to work at the right time because most men are not able to predict when they will have an orgasm. Infertility treatments
If a couple is experiencing infertility as a result of retrograde ejaculation and medications are not helping, the collection of the semen collection may undergo a special procedure. First, the patient alkalinizes his urine by intake of sodium bicarbonate (3g dissolved in water in the evening before bed, and then another dose after complete bladder emptying  right before going to the laboratory). Before semen collection the patient must empty his bladder. The patient then has to masturbate in one container and immediately after has to urinate in another container. The males ejaculate may be centrifuged from urine voided, and the isolated sperm injected directly into the woman through the use of intrauterine insemination.
Botryomycosis; is a rare chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera. : 255 Botryomycosis has been known to affect humans, horses, cattle, swine, dogs and cats. Presentation
Associated conditions
There are only a handful of documented cases of botryomycosis in humans, and its pathogenesis is not completely understood. However, it is usually described in individuals with impaired immunity, or with an underlying disease such as diabetes mellitus, cystic fibrosis or HIV infection. Causes
Staphylococcus aureus is usually the organism that causes the infection, however it can also be caused by Pseudomonas aeruginosa, Pneumocystis carinii, Proteus spp. and Actinobacillus lignieresii or other species of bacteria. The anatomic structure of its lesion is similar to that of actinomycosis and eumycetoma, and its granules resemble the sulfur granules of actinomycosis. Diagnosis
History
The disease was originally discovered by Otto Bollinger (1843–1909) in 1870, and its name was coined by Sebastiano Rivolta (1832–1893) in 1884. The name refers to its grape-like granules (Gr. botryo = grapes) and the mistakenly implied  fungal etiology (Gr. mykes = fungus). In 1919 the bacterial origin of the infection was discovered. Notes
Concise Review of Veterinary Microbiology - Quinn and Markey 2003

External links
Essay on Pulmonary Botryomycosis