If there are mouth ulcers or skin lesions, the disease is likely to be widespread.Two presentations are known, firstly the acute or subacute form, which predominantly affects children and young adults, and the chronic form, predominantly affecting adult men. Most cases are infected before age 20, although symptoms may present many years later. Juvenile (acute/subacute) form
The juvenile, acute form is characterised by symptoms, such as fever, weight loss and feeling unwell together with enlarged lymph nodes and enlargement of the liver and spleen. This form is most often disseminated, with symptoms manifesting depending on the organs involved. Skin and mucous membrane lesions are often present, and bone involvement may occur in severe cases. This acute, severe presentation may mimic tuberculosis, lymphoma or leukaemia. Adult (chronic) form
The chronic form presents months to years after the initial infection occurs and most frequently presents with dry cough and shortness of breath. Other symptoms include excess salivation, difficulty swallowing, and difficulties with voice control. Upper respiratory tract mucosal lesions may be present, as well as increased mucus production and coughing up blood. Both pulmonary and extrapulmonary involvement is common.Up to 70% of cases have mucosal involvement, with lesions often found in the mouth, oropharynx, larynx, and palate. Classic lesions are superficial painful granular ulcers, with small spots of bleeding. Cause
Paracoccidioidomycosis is caused by two species of fungi that can exist as a mold or yeast depending on temperature, P. brasiliensis and P. lutzii.
Pes (Latin for "foot") or the acronym PES may refer to:

Pes
Pes (unit), a Roman unit of length measurement roughly corresponding with a foot
Pes or podatus, a Neume § Neumes representing two notes
Pes (rural locality), several rural localities in Russia
Pes (river), a river in northwestern Russia
Pes (anatomy), zoological term for the distal portion of the hind limb of tetrapod animals
Talipes equinovarus (pes equinovarus), clubfoot
Talipes cavus (pes cavus), clawfoot
Talipes planus (pes planus), flat feet
Talipes valgus (pes valgus), valgus deformity of the foot
Talipes varus (pes varus), varus deformity of the foot
Pes anserinus (leg)
Pes anserine bursitis, inflammatory of the inner knee at the bursa of the pes anserinus
Parotid plexus, pes anserinus of the facial nerve

PES
Education
PES University, formerly P.E.S.