(S)-Oxybutynin has not been clinically tested for its spasmolytic effects, but may be clinically useful for the same indications as the racemate, without the unpleasant anticholinergic side effects. Brand names
Oxybutynin is available by mouth in generic formulation and under the brand names Ditropan, Lyrinel XL, Ditrospam, Kentera, and Aquiette, as a transdermal patch under the brand name Oxytrol, and as a topical gel under the brand name Gelnique. See also
Arecoline

References
External links
"Oxybutynin". Drug Information Portal. U.S. National Library of Medicine.
The condition was first described between 1888 and 1891. Signs and symptoms
The condition is typically seen in premature infants, and the timing of its onset is generally inversely proportional to the gestational age of the baby at birth (i.e., the earlier a baby is born, the later signs of NEC are typically seen).Initial symptoms include feeding intolerance and failure to thrive, increased gastric residuals, abdominal distension, and bloody stools. Symptoms may progress rapidly to abdominal discoloration with intestinal perforation and peritonitis and systemic hypotension requiring intensive medical support. Cause
The exact cause is unclear. Several risk factors have been implicated:

Maternal factors
Acid-suppressing medications
Chorioamnionitis
Cocaine abuse
In utero growth restriction
Increased body mass index
Intrahepatic cholestasis during pregnancy
Lack of prenatal steroids
Mode of delivery
Placental abruption
Pre-eclampsia
Smoking

Main risk factors
Low birth weight
Prematurity
Formula feeding (bovine based)
Intestinal dysbiosis

Other risk factors
Acute hypoxia
Antibiotic exposure
Blood transfusions
Cardiac anomalies
Neonatal anemia
Poor intestinal perfusion
Prolonged use of indomethacin for patent  ductus arteriosus closure

Diagnosis
Diagnosis is usually suspected clinically, but often requires the aid of diagnostic imaging, most commonly radiography, which can show the intestines and may show areas with death tissue or a bowel perforation.