This is associated with increased pressure in the eye. Not all people with primary open-angle glaucoma have eye pressure that is elevated beyond normal, but decreasing the eye pressure further has been shown to stop progression even in these cases. The increased pressure is caused by trabecular meshwork blockage. Because the microscopic passageways are blocked, the pressure builds up in the eye and causes imperceptible very gradual vision loss. Peripheral vision is affected first, but eventually the entire vision will be lost if not treated. Diagnosis is made by looking for cupping of the optic nerve. Prostaglandin agonists work by opening uveoscleral passageways. Beta-blockers, such as timolol, work by decreasing aqueous formation. Carbonic anhydrase inhibitors decrease bicarbonate formation from ciliary processes in the eye, thus decreasing the formation of aqueous humor. Parasympathetic analogs are drugs that work on the trabecular outflow by opening up the passageway and constricting the pupil. Alpha 2 agonists (brimonidine, apraclonidine) both decrease fluid production (via inhibition of AC) and increase drainage. Developmental glaucoma
Developmental glaucoma (Q15.0)

Primary congenital glaucoma
Infantile glaucoma
Glaucoma associated with hereditary or familial diseases

Secondary glaucoma
Secondary glaucoma (H40.3-H40.6)

Inflammatory glaucomaUveitis of all types
Fuchs heterochromic iridocyclitisPhacogenic glaucomaAngle-closure glaucoma with mature cataract
Phacoanaphylactic glaucoma secondary to rupture of lens capsule
Phacolytic glaucoma due to phacotoxic meshwork blockage
Subluxation of lensGlaucoma secondary to intraocular hemorrhageHyphema
Hemolytic glaucoma, also known as erythroclastic glaucomaTraumatic glaucomaAngle recession glaucoma: Traumatic recession on anterior chamber angle
Postsurgical glaucomaAphakic pupillary block
Ciliary block glaucomaNeovascular glaucoma (see below for more details)
Drug-induced glaucomaCorticosteroid induced glaucoma
Alpha-chymotrypsin glaucoma.
If all the isopters show similar depression to the same point, it is then called a contraction of visual field. Relative paracentral scotomas are the areas where smaller and dimmer targets are not visualized by the patient. Larger and brighter targets can be seen. Small paracentral depressions, mainly superonasal are seen in normal tension glaucoma (NTG). The generalized depression of the entire field may be seen in cataract also. Baring of blind spot: "Baring of blind spot" means exclusion of blind spot from the central field due to inward curve of the outer boundary of 30° central field. It is only an early non-specific visual field change, without much diagnostic value in glaucoma. Small wing-shaped Paracentral scotoma: Small wing-shaped Paracentral scotoma within Bjerrums area is the earliest clinically significant field defect seen in glaucoma. It may also be associated with nasal steps. Scotoma may be seen above or below the blind spot. Siedels sickle-shaped scotoma: Paracentral scotoma joins with the blind spot to form the Seidel sign. Arcuate or Bjerrums scotoma:  It is formed at later stages of glaucoma by extension of Seidels scotoma in an area either above or below the fixation point to reach the horizontal line. Peripheral breakthrough may occur due to damage of nerve fibers. Ring or Double arcuate scotoma: Two arcuate scotomas join to form a Ring or Double arcuate scotoma. This defect is seen in advanced stages of glaucoma.