There may be multiple determinants of violence against civilians in such situations. Economic violence includes attacks motivated by economic gain—such as attacks carried out with the purpose of disrupting economic activity, denying access to essential services, or creating economic division and fragmentation. Clearly, acts committed by domestic and subnational groups can have multiple motives. Slow violence is a long-duration form of violence which is often invisible (at least to those not impacted by it), such as environmental degradation, pollution and climate change. Warfare
War is a state of prolonged violent large-scale conflict involving two or more groups of people, usually under the auspices of government. It is the most extreme form of collective violence. War is fought as a means of resolving territorial and other conflicts, as war of aggression to conquer territory or loot resources, in national self-defence or liberation, or to suppress attempts of part of the nation to secede from it. There are also ideological, religious and revolutionary wars.Since the Industrial Revolution the lethality of modern warfare has grown. World War I casualties were over 40 million and World War II casualties were over 70 million. Interpersonal
Interpersonal violence is divided into two subcategories: Family and intimate partner violence—that is, violence largely between family members and intimate partners, usually, though not exclusively, taking place in the home. Community violence—violence between individuals who are unrelated, and who may or may not know each other, generally taking place outside the home.
Vasopressin stimulates the release of ACTH, which indirectly increases responsiveness of alpha-1 receptor in blood vessel smooth muscle, increasing vessel tone and blood pressure. Several studies have shown that Desmopressin does not stimulate ACTH release (except in Cushings Disease), and therefore does not directly raise blood pressure, however, one study showed that it stimulates ACTH release in over 50% of healthy subjects. Additionally, desmopressin is able to enhance ACTH and cortisol release in normal subjects following oCRH administration, but not in patients with anorexia nervosa. Chemistry
Desmopressin (1-deamino-8-D-arginine vasopressin) is a synthetic form of the normal human hormone arginine vasopressin (the antidiuretic hormone, or ADH), a peptide containing nine amino acids. Compared to vasopressin, desmopressins first amino acid has been deaminated, and the arginine at the eighth position is in the dextro rather than the levo form (see stereochemistry). References
Further reading
Leissinger, C; Becton, D; Cornell, C Jr; Cox Gill, J (2001). "High-dose DDAVP intranasal spray (Stimate) for the prevention and treatment of bleeding in patients with mild haemophilia A, mild or moderate type 1 von Willebrand disease and symptomatic carriers of haemophilia A.". Haemophilia. 7 (3): 258–66. doi:10.1046/j.1365-2516.2001.00500.x. PMID 11380629. S2CID 20472310. External links
"Desmopressin". Drug Information Portal. U.S. National Library of Medicine.