To remove the growths, the patient underwent may surgical procedures where the nodules were effectively excised. The growth was described as a:“ten centimetre, firm, lobulated mass with skin ulceration and muscle involvement was removed. Microscopic examination revealed infiltrating nests of medium to large epithelial cells embedded in a chondromyxoid matrix with few scattered plasmacytoid myoepithelial cells. There was brisk mitosis as well as large areas of tumour necrosis. All auxiliary lymph nodes were negative for tumour.” (Garcia, Atun, and Fernando, 2016)From this information, Garcia, Atun, and Fernando diagnosed the patient with malignant chondroid syringoma. After the surgery, the patient developed further growths on the scalp, face, body, upper right arm, and right foot. He was recommended chemotherapy however died before treatment began. Lymph node metastasis after excision
This journal, written by Watarai, Amoh, Aki, Takasu, and Katsuoka discusses a case of malignant chondroid syringoma on a forty-six-year-old man and the state his diagnosis 12 years after excision. Originally in 1996, the man observed an “asymptomatic, enlarging nodule” (Watarai, Amoh, Aki, Takasu, and Katsuoka, 2011) on the sole of his right foot and proceeded to undergo an initial biopsy where he was not diagnosed. Physically, the nodule was “solitary, dome-shaped, skin coloured, and firm,” (Watarai, Amoh, Aki, Takasu, and Katsuoka, 2011) and was 30 mm x 30 mm. The tumour underwent excision utilising a three-millimetre margin. The nodule was then replaced with grafting of the transplanted skin.
Spinal muscular atrophy with lower extremity predominance, sometimes called lower extremity-predominant spinal muscular atrophy, may refer to:

Spinal muscular atrophy with lower extremity predominance 1
Spinal muscular atrophy with lower extremity predominance 2A
Spinal muscular atrophy with lower extremity predominance 2B

See also
Spinal muscular atrophies