Conditions with similar symptoms must first be ruled out.There is a certain criteria that must be met for the diagnosis. A blood test can rule in or rule out the presence of the MECP2 mutation, however, this mutation is present in other conditions as well.For a classic diagnosis, all four criteria for ruling in a diagnosis must be met, as well as the two criteria for ruling out a diagnosis. Supportive criteria may also be present, but are not required for diagnosis. For an atypical or variant diagnosis, at least two of the four criteria for ruling in the diagnosis must be met, as well as five of the eleven supportive criteria. A period of symptom regression followed by recovery or symptom stabilization must also occur. Children are often misdiagnosed as having autism, cerebral palsy, or another form of developmental delay.
(The exception is the vaginal suppository, which is not available as a generic in the US). Veterinary use
The veterinary uses of clindamycin are quite similar to its human indications, and include treatment of osteomyelitis, skin infections, and toxoplasmosis, for which it is the preferred drug in dogs and cats. They can be used both by mouth and topically. A disadvantage is that bacterial resistance can develop fairly quickly. Gastrointestinal upset may also occur. Toxoplasmosis rarely causes symptoms in cats, but can do so in very young or immunocompromised kittens and cats. References
External links
"Clindamycin". Drug Information Portal. U.S. National Library of Medicine. "Clindamycin hydrochloride". Drug Information Portal. U.S. National Library of Medicine. Clinical trial number NCT04370548 for "DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE)" at ClinicalTrials.gov