Diagnosis
Clinical features of myxedema coma:
Cardiovascular
Bradycardia
Bundle branch blocks
Complete heart block and arrhythmias
Cardiomegaly
Elevated diastolic blood pressure—early
Hypotension—late
Low cardiac output
Non-specific ECG findings
Pericardial effusion
Polymorphic ventricular tachycardia (torsades de pointes)
Prolonged QT interval
Respiratory
Hypoxia
Hypercapnia
Hyperventilation
Myxedema of the larynx
Pleural effusion
Gastrointestinal
Abdominal distention
Abdominal pain
Anasarca
Anorexia and nausea
Decreased motility
Fecal impaction and constipation
Gastrointestinal atony or ileus
Myxedema or toxic megacolon—late
Neurogenic oropharyngeal dysphagia
ileus
Neurological
Altered mentation
Coma
Confusion and obtundation
Delayed tendon reflexes
Depression
Poor cognitive function
Psychosis
Seizures
Renal and urinary function
Bladder dystonia and distension
Fluid retention
Appearance and dermatological
Alopecia
Coarse, sparse hair
Dry, cool, doughy skin
Myxedematous face
Generalized swelling
Goiter
Macroglossia
Non-pitting edema
Ptosis
Periorbital edema
Surgical scar from prior thyroidectomy
HypothermiaLaboratory features in myxedema coma:
Anemia
Elevated creatine kinase (CPK)
Elevated creatinine
Elevated transaminases
Hypercapnia
Hypercholesterolemia (elevated LDL)
Hyperlipidemia
Hypoglycemia
Hyponatremia
Hypoxia
Leukopenia
Respiratory acidosis

Epidemiology
Hypothyroidism is four times more common in women than men. The incidence of myxedema coma has been reported to be 0.22 per 1000000 per year but the data is limited and especially lacking in countries outside the western world and countries along the equator. Myxedema coma is most common in people 60 years old and older and is most common in the winter months when hypothermia is more common. See also
Thyroid storm
Euthyroid sick syndrome

References


== External links ==
The Indian Institute of Infrastructure and Construction Kollam or IIIC-Kollam is a public institute of international standard situated at Chavara in Kollam, Kerala. The initiative has been undertaken by the Government of Kerala with the support of the Government of India. The academy is coming under the Kerala Academy for Skills Excellence (KASE) to support the skill development programmes for construction related occupations

History
The construction academy was first proposed by the LDF ministry during 2008. They started the background works for the academy and named the project as Kerala Construction Academy, proposed at Chathannoor in Kollam district. When UDF came into power, they have shifted the project from Chathannoor to chavara and renamed as Indian Institute of Infrastructure and Construction. Campus
The institute is on a 9.02 acres (36,500 m2) campus along the NH-66, near chavara in Kollam Metropolitan Area. KASE has developed a Master Plan and detailed design for the campus with 235,100 square feet (21,800 m2) of facilities including an administrative block, training block, canteen, and substation. Foundation stone was laid by the then Chief Minister of Kerala Mr. Oommen Chandy on 15 March 2013. The campus was inaugurated for academic activities by the Hon. Chief Minister Shri. Pinarayi Vijayan in August 2018. Courses
During the initial phase, there will be three technician and managerial level courses along with a course in supervisory level. There will be an advanced certificate programme also in plumbing engineering. Candidates with SSLC, Plus Two, ITI, diploma, degree and B.Tech qualification can join for the courses.