Acute stage
Tranexamic acid within three hours of a head injury decreases the risk of death. Certain facilities are equipped to handle TBI better than others; initial measures include transporting patients to an appropriate treatment center. Both during transport and in hospital the primary concerns are ensuring proper oxygen supply, maintaining adequate blood flow to the brain, and controlling raised intracranial pressure (ICP), since high ICP deprives the brain of badly needed blood flow and can cause deadly brain herniation. Other methods to prevent damage include management of other injuries and prevention of seizures. Some data supports the use of hyperbaric oxygen therapy to improve outcomes. Further research is required to determine the effectiveness and clinical importance of positioning the head at different angles (degrees of head-of-bed elevation) while the person is being treated in intensive care.Neuroimaging is helpful but not flawless in detecting raised ICP. A more accurate way to measure ICP is to place a catheter into a ventricle of the brain, which has the added benefit of allowing cerebrospinal fluid to drain, releasing pressure in the skull. Treatment of raised ICP may be as simple as tilting the persons bed and straightening the head to promote blood flow through the veins of the neck. Sedatives, analgesics and paralytic agents are often used. Propofol and midazolam are equally effective as sedatives.Hypertonic saline can improve ICP by reducing the amount of cerebral water (swelling), though it is used with caution to avoid electrolyte imbalances or heart failure.
Erythema gyratum repens  is a figurate erythema that is rapidly moving and usually a marker of underlying cancer,: 143  usually from the lung. See also
Annular erythema of infancy
List of cutaneous conditions
List of cutaneous conditions associated with internal malignancy
List of migrating cutaneous conditions

References
Further reading
Prouty, Megan; Liu, Deede (2019). "Erythema Gyratum Repens Associated with Anal Cancer". New England Journal of Medicine. 380 (3): e3. doi:10.1056/NEJMicm1805833. ISSN 0028-4793. PMID 30650327. Illustration of the condition


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