ITNs and IRS may not be sufficient to eliminate the disease, as these interventions depend on how many people use nets, how many gaps in insecticide there are (low coverage areas), if people are not protected when outside of the home, and an increase in mosquitoes that are resistant to insecticides. Modifications to peoples houses to prevent mosquito exposure may be an important long term prevention measure. Insecticide-treated nets
Mosquito nets help keep mosquitoes away from people and reduce infection rates and transmission of malaria. Nets are not a perfect barrier and are often treated with an insecticide designed to kill the mosquito before it has time to find a way past the net. Insecticide-treated nets (ITNs) are estimated to be twice as effective as untreated nets and offer greater than 70% protection compared with no net. Between 2000 and 2008, the use of ITNs saved the lives of an estimated 250,000 infants in Sub-Saharan Africa. About 13% of households in Sub-Saharan countries owned ITNs in 2007 and 31% of African households were estimated to own at least one ITN in 2008. In 2000, 1.7 million (1.8%) African children living in areas of the world where malaria is common were protected by an ITN. That number increased to 20.3 million (18.5%) African children using ITNs in 2007, leaving 89.6 million children unprotected and to 68% African children using mosquito nets in 2015. Most nets are impregnated with pyrethroids, a class of insecticides with low toxicity. They are most effective when used from dusk to dawn.
CMS prevalence rates reported from the study are summarised below:

Ethiopia [3600–4100 m]: 0%
Tibetan Plateau (Tibetans): 0.91–1.2%
Indian Himalayas [3000–4200 m]: 4–7%
Kyrgyzstan [3000–4200 m]: 4.6%
Tibetan Plateau (Han Chinese): 5.6%
La Paz, Bolivia [3600 m]: 6% to 8%
Bolivia: 8–10%
Cerro de Pasco, Peru [4300 m]: 14.8–18.2%

References
External links

^  Online calculator illustrating blood oxygen carrying capacity at altitude