Apremilast may also be used to treat oral ulcers associated with Behçets disease.Interferon alpha-2a may also be an effective alternative treatment, particularly for the genital and oral ulcers as well as ocular lesions. Azathioprine, when used in combination with interferon alpha-2b also shows promise, and colchicine can be useful for treating some genital ulcers, erythema nodosum, and arthritis. Benzathine‐penicillin may also reduce new arthritic attacks.Thalidomide has also been used due to its immune-modifying effect. Dapsone and rebamipide have been shown, in small studies, to have beneficial results for mucocutaneous lesions.Given its rarity, the optimal treatment for acute optic neuropathy in Behçets disease has not been established. Early identification and treatment are essential. Response to ciclosporin, periocular triamcinolone, and IV methylprednisone followed by oral prednisone has been reported although relapses leading to irreversible visual loss may occur even with treatment. Immunosuppressants such as interferon-alpha and tumour necrosis factor antagonists may improve though not completely reverse symptoms of ocular Behçets disease, which may progress over time despite treatment. When symptoms are limited to the anterior chamber of the eye prognosis is improved. Posterior involvement, particularly optic nerve involvement, is a poor prognostic indicator. Secondary optic nerve atrophy is frequently irreversible. Lumbar puncture or surgical treatment may be required to prevent optic atrophy in cases of intracranial hypertension refractory to treatment with immunomodulators and steroids.IVIG could be a treatment for severe or complicated cases.
Joe: Americas Elite
The Plague, a duo of demonic assassins in the movie Hobo with a Shotgun

Films and television
Plague (1979 film), a science-fiction film
The Plague (1992 film), a drama film
The Plague (2006 film), a horror film
Plague (2014 film), an Australian horror film
La peste (TV series), Spanish historical drama series broadcast in the UK as The Plague

Games
Corrupted Blood incident, a virtual plague that occurred in the video game World of Warcraft
Plague Inc., a strategy game for smartphones and tablets by Ndemic Creations
Plague!, a card game about the Black Plague in England
Plague of Shadows (Plague Knight), a character and DLC gamemode for Shovel Knight
The Plague, a playable killer character of Babylonian origin from the asymmetrical-survival horror Dead by Daylight

Literature
Plague, a 2000 young adult novel by Malcolm Rose
Plague, a 1977 thriller novel by Graham Masterton
Plague 99, a novel by Jean Ure
The Plague (novel), a novel by Albert Camus
"The Plague" (Dragon Prince), an epidemic which affects both humans and dragons in Melanie Rawns novel
The Plague (magazine), New York Universitys comedy magazine

Music
Artists
The Plague (American band), a hardcore punk band from Cleveland
The Plague (English band), a punk rock band
The Plague (New Zealand band), a theatrical punk/art rock band

Albums
Plague (Klinik album)
Plagues (album), by The Devil Wears Prada
The Plague, by Demon
The Plague (Brotha Lynch Hung album)

EPs
The Plague (Nuclear Assault EP)
The Plague (I Hate Sally EP)

Songs
"Plague", by Crystal Castles from the 2012 album III
"The Plague", by Demon from the 1983 album by the same name
"The Plague," an unreleased song by The Mountain Goats that appears on the 2020 live album The Jordan Lake Sessions

Musicals
Plague!