Schistosomiasis caused by trematodes of the genus Schistosoma: As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis
Paragonimiasis caused by infection with lung flukes, mostly of the species Paragonimus westermani
Fasciolopsiasis caused by intestinal fluke Fasciolopsis buski

Side effects
The majority of side effects develop due to the release of the contents of the parasites as they are killed and the consequent host immune reaction. The heavier the parasite burden, the heavier and more frequent the side effects normally are. Central nervous system (CNS): Frequently occurring side effects are dizziness, headache, and malaise. Drowsiness, somnolence, fatigue, and vertigo have also been seen. Almost all patients with cerebral cysticercosis experience CNS side effects related to the cell-death of the parasites (headache, worsening of pre-existing neurological problems, seizures, arachnoiditis, and meningism). These side effects may be life-threatening and can be reduced by coadministration of corticosteroids. All patients with cerebral cysticercosis are strongly recommended to be  hospitalized during treatment. Gastrointestinal tract: About 90% of all patients have abdominal pain or cramps with or without nausea and vomiting. Diarrhea may develop and may be severe with colic. Sweating, fever, and sometimes bloody stools may occur together with diarrhea. Liver: Asymptomatic and transient increases of liver enzymes (AST and ALT) are noted frequently (up to 27%). No case of symptomatic liver damage has been seen so far.
Kaicide (Taiwan)
Milbemax (combination with milbemycin oxime) (Novartis) for veterinary use
Popantel (Jurox)
PraziPro (Hikari) for aquarium use
Praz-Tastic (NFP/National Fish Pharmaceuticals) for aquarium use
Pure Prazi (COTS Koi/Children of the Sun Koi) for aquarium use
PraziPure (J.K.O., Inc. d/b/a Kodama Koi Farm & Kodama Koi Garden; licensed by COTS Koi) for aquarium use
Profender (combination with emodepside) (Bayer) for veterinary use
Tape Worm Tabs (Trade Winds) for veterinary use
Zentozide (Berich (Thailand) Co)

Regulatory approval
Praziquantel is on the World Health Organizations List of Essential Medicines.Praziquantel is not licensed for use in humans in the UK, but it can be imported when necessary on a named-patient basis. It is available in the UK as a veterinary anthelmintic. Praziquantel is FDA approved in the US for the treatment of schistosomiasis and liver flukes, although it is effective in other infections. Veterinary medicine
Salmon poisoning disease
Diplozoon paradoxum and other Trematoda infections of many fish speciesIt may cause problems in dogs with MDR1 mutations. See also
Fenbendazole
Oxfendazole
Nocodazole

References
External links

"Praziquantel (Rx) Biltricide". Medscape. WebMD. Retrieved 2015-11-01. "Praziquantel". Drug Information Portal. U.S. National Library of Medicine.