For example, after using a very helium-rich trimix at the deepest part of the dive, a diver will switch to mixtures containing progressively less helium and more oxygen and nitrogen during the ascent. Nitrogen diffuses into tissues 2.65 times slower than helium but is about 4.5 times more soluble. Switching between gas mixtures that have very different fractions of nitrogen and helium can result in "fast" tissues (those tissues that have a good blood supply) actually increasing their total inert gas loading. This is often found to provoke inner ear decompression sickness, as the ear seems particularly sensitive to this effect. Bubble formation
The location of micronuclei or where bubbles initially form is not known. The most likely mechanisms for bubble formation are tribonucleation, when two surfaces make and break contact (such as in joints), and heterogeneous nucleation, where bubbles are created at a site based on a surface in contact with the liquid. Homogeneous nucleation, where bubbles form within the liquid itself is less likely because it requires much greater pressure differences than experienced in decompression. The spontaneous formation of nanobubbles on hydrophobic surfaces is a possible source of micronuclei, but it is not yet clear if these can grow large enough to cause symptoms as they are very stable.Once microbubbles have formed, they can grow by either a reduction in pressure or by diffusion of gas into the gas from its surroundings. In the body, bubbles may be located within tissues or carried along with the bloodstream.
It became "quite common" for members of the Tractarian movement within the Anglican Communion to practice self-flagellation using a discipline.Historically speaking, in the 11th century, Peter Damian, a Benedictine Christian monk in the Roman Catholic tradition, taught that spirituality should manifest itself in physical discipline; he admonished those who sought to follow Christ to practice self-flagellation for the duration of the time it takes one to recite forty Psalms, increasing the number of flagellations on holy days of the liturgical calendar. For Damian, only those who shared in the sufferings of Christ could be saved. Throughout Christian history, the mortification of the flesh, wherein one denies themselves physical pleasures, has been commonly followed by members of the clergy, especially in Christian monasteries and convents; the 11th-century Dominicus Loricatus repeated the entire Psalter twenty times in one week, accompanying each psalm with a hundred lash-strokes to his back. The distinction of the Flagellants was to take this self-mortification into the cities and other public spaces as a demonstration of piety. Flagellantism
Flagellantism was a 14th-century movement, consisting of penitents in the Catholic Church. It began as a Christian pilgrimage and was later condemned by the Catholic Church as heretical. The followers were noted for including public flagellation in their rituals. This was a common practice during the Black Death, or the Great Plague. Spread in the 14th century
The first recorded incident was in Central Italy in Perugia, in 1259, the year after severe crop damage and famine throughout Europe.