Adverse effects
The high cure rates and long survival of many people with Hodgkin lymphoma has led to a high concern with late adverse effects of treatment, including cardiovascular disease and second malignancies such as acute leukemias, lymphomas, and solid tumors within the radiation therapy field. Most people with early-stage disease are now treated with abbreviated chemotherapy and involved site radiation therapy rather than with radiation therapy alone. Clinical research strategies are exploring reduction of the duration of chemotherapy and dose and volume of radiation therapy in an attempt to reduce late morbidity and mortality of treatment while maintaining high cure rates. Hospitals are also treating those who respond quickly to chemotherapy with no radiation.In childhood cases of Hodgkin lymphoma, long-term endocrine adverse effects are a major concern, mainly gonadal dysfunction and growth retardation. Gonadal dysfunction seems to be the most severe endocrine long-term effect, especially after treatment with alkylating agents or pelvic radiotherapy.It is possible that patients undergoing a chemotherapy need a platelet transfusion. If a stem cell transplantation is necessary for the treatment of a relapse, graft-versus-host diseases might occur. Supportive treatment
Adding physical exercises to the standard treatment for adult patients with haematological malignancies like Hodgkin lymphoma may result in little to no difference in the mortality, the quality of life and the physical functioning. These exercises may result in a slight reduction in depression. Furthermore, aerobic physical exercises probably reduce fatigue. The evidence is very uncertain about the effect on anxiety and serious adverse events.
Daniel Hauser, whose mother fled with him in 2009 in order to prevent him from undergoing chemotherapy. Tessa James, Australian actress, was diagnosed in 2014. Sean Kent, American stand up comedian and actor. Was diagnosed in 2002 while writing on a TV show. After three months in remission the cancer returned and he was given an autologous stem cell transplant at City of Hope Cancer Hospital in Los Angeles. Currently lives in Texas with his wife and family and still performs many weeks a year. Mario Lemieux, Hall of Fame NHL player, co-owner of the Pittsburgh Penguins and founder of the Mario Lemieux Foundation, diagnosed in 1993. Dinu Lipatti (1917–1950), Romanian classical pianist and composer. Diagnosed in 1947, received cortisone treatment in 1949; died from a burst abscess on his one lung. Jack Lisowski, English snooker player, diagnosed in 2008 at the age of 16. Mamta Mohandas, Indian film actress and producer, diagnosed in 2010. Nanni Moretti, Italian actor and director. Laura Packard, health care activist diagnosed in 2017, spoke at the 2020 Democratic National Convention. Nikola Pokrivač, Croatian soccer midfielder, diagnosed in 2015. Anthony Rizzo, MLB All-Star first baseman for the New York Yankees, diagnosed in May 2008 while signed as a minor league player for the Boston Red Sox. Dave Roberts, MLB outfielder and manager of the Los Angeles Dodgers. Diagnosed in March 2010 while he was a coach for the San Diego Padres. Chip Roy, Texas congressman.