Uses
Medical
Methyltestosterone is or has been used in the treatment of delayed puberty, hypogonadism, cryptorchidism, and erectile dysfunction in males, and in low doses to treat menopausal symptoms (specifically for osteoporosis, hot flashes, and to increase libido and energy), postpartum breast pain and engorgement, and breast cancer in women. It is specifically approved in the United States for the treatment of hypogonadism and delayed puberty in males and the treatment of advanced inoperable breast cancer in females. It was also approved in low doses in combination with esterified estrogens for the treatment of moderate to severe vasomotor symptoms associated with menopause in women in the United States, but this formulation was discontinued and hence is no longer used.Methyltestosterone is less effective in inducing masculinization than testosterone, but is useful for maintaining established masculinization in adults.The dosages of methyltestosterone used are 10 to 50 mg/day in men for common medical uses like hypogonadism and delayed puberty as well as physique- and performance-enhancing purposes and 2.5 mg/day in women for menopausal symptoms. Higher dosages of 50 to 200 mg/day have been used to treat women with inoperable breast cancer that has failed to respond to other therapies, although such dosages are associated with severe irreversible virilization. Non-medical
Methyltestosterone is used for physique- and performance-enhancing purposes by competitive athletes, bodybuilders, and powerlifters, although it is not commonly used relative to other AAS for such purposes. Available forms
Methyltestosterone is typically used as an oral medication.
KP does not bear any known, long-term health implications, nor is it associated with increased mortality or morbidity. It is not related to goose bumps, which result from muscle contractions, except that both occur in the area where the hair shaft exits the skin. Gallery
Treatment
KP is medically harmless, but many individuals may seek treatment, as the condition can cause emotional distress. Topical creams and lotions are currently the most commonly used treatment for KP, specifically those consisting of moisturizing or keratolytic treatments, including urea, lactic acid, glycolic acid, salicylic acid, vitamin D, fish oil, or topical retinoids such as tretinoin. Improvement of the skin often takes months, and the bumps are likely to return. Limiting time in the shower and using gentle exfoliation to unplug pores can help. Many products are available that apply abrasive materials, with alpha or beta hydroxy acids to assist with exfoliation. Some cases of KP have been successfully treated with laser therapy, which involves passing intense bursts of light into targeted areas of the skin. Depending on the bodys response to the treatment, multiple sessions over the course of a few months may be necessary. Epidemiology
Worldwide, KP affects an estimated 30 to 50% of the adult population, and around 50 to 80% of all adolescents. It is more common in women than in men, and it is often present in otherwise healthy individuals. The skin condition is prevalent in persons of all ethnicities, and no particular ethnicity is at higher risk for developing KP.