The minimum inhibitory concentration susceptibility data for a few medically significant bacteria are:
S. aureus: 0.25 μg/mL to 4.0 μg/mL
S. aureus (methicillin resistant or MRSA): 1 μg/mL to 138 μg/mL
S. epidermidis: ≤0.12 μg/mL to 6.25 μg/mL

Side effects
Serum vancomycin levels may be monitored in an effort to reduce side effects, although the value of such monitoring has been questioned. Peak and trough levels are usually monitored, and for research purposes, the area under the concentration curve is also sometimes used. Toxicity is best monitored by looking at trough values.Common adverse drug reactions (≥1% of patients) associated with IV vancomycin include: local pain, which may be severe, and thrombophlebitis. Damage to the kidneys (nephrotoxicity) and to the hearing (ototoxicity) were side effects of the early impure versions of vancomycin, and these were prominent in the clinical trials conducted in the mid-1950s. Later trials using purer forms of vancomycin found nephrotoxicity is an infrequent adverse effect (0.1% to 1% of patients), but this is accentuated in the presence of aminoglycosides.Rare adverse effects (<0.1% of patients) include: anaphylaxis, toxic epidermal necrolysis, erythema multiforme, red man syndrome, superinfection, thrombocytopenia, neutropenia, leukopenia, tinnitus, dizziness and/or ototoxicity, and DRESS syndrome.Vancomycin can induce platelet-reactive antibodies in the patient, leading to severe thrombocytopenia and bleeding with florid petechial hemorrhages, ecchymoses, and wet purpura.Vancomycin has traditionally been considered a nephrotoxic and ototoxic drug, based on observations by early investigators of elevated serum levels in renally impaired patients who had experienced ototoxicity, and subsequently through case reports in the medical literature.
A blighted ovum is a pregnancy in which the embryo never develops or develops and is reabsorbed. In a normal pregnancy, an embryo would be visible on an ultrasound by six weeks after the womans last menstrual period. Anembryonic gestation is one of the causes of miscarriage of a pregnancy.A blighted ovum or anembryonic gestation is characterized by a normal-appearing gestational sac, but the absence of an embryo. It likely occurs as a result of early embryonic death with continued development of the trophoblast. When small, the sac cannot be distinguished from the early normal pregnancy, as there may be a yolk sac, though a fetal pole is not seen. For diagnosis, the sac must be of sufficient size that the absence of normal embryonic elements is established. The criteria depends on the type of ultrasound exam performed. A pregnancy is anembryonic if a transvaginal ultrasound reveals a sac with a mean gestational sac diameter (MGD) greater than 25 mm and no yolk sac, or an MGD >25 mm with no embryo. Transabdominal imaging without transvaginal scanning may be sufficient for diagnosing early pregnancy failure when
an embryo whose crown–rump length is 15 mm or more has no visible cardiac activity. See also
Ovum
Products of conception

References
External links

Blighted Ovum on WebMD
Anembryonic pregnancy on Radiopaedia.org
Johnson, MR; Riddle, AF; Sharma, V; Collins, WP; Nicolaides, KH; Grudzinskas, JG (January 1993). "Placental and ovarian hormones in anembryonic pregnancy". Human Reproduction (Oxford, England). 8 (1): 112–5. doi:10.1093/oxfordjournals.humrep.a137857. PMID 8458911.