Return-to-school
The resumption of low-risk school activities should begin as soon as the student feels ready and has completed an initial period of cognitive rest of no more than 24–48 hours following the acute injury. Long absences from school are not suggested, however, the return to school should be gradual and step-wise. Prolonged complete mental or physical rest (beyond 24–48 hours after the accident that lead to the concussion) may worsen outcomes, however, rushing back to school before the person is ready, has also been associated with longer-lasting symptoms and an extended recovery time. Students with a suspected concussion are required to see a doctor for an initial medical assessment and for suggestions on recovery, however, medical clearance is not required for a student to return to school. Since students may appear normal, continuing education of relevant school personnel may be needed to ensure appropriate accommodations are made such as part-days and extended deadlines. Accommodations should be based on the monitoring of symptoms that are present during the return-to-school transition including headaches, dizziness, vision problems, memory loss, difficulty concentrating, and abnormal behavior. Students must have completely resumed their school activities (without requiring concussion-related academic supports) before returning to full-contact sports. Return-to-sport
For persons participating in athletics, it is suggested that participants progress through a series of graded steps. These steps include:

Immediately after injury: 24–48 hours (maximum) of relative physical and cognitive rest. Stage 1: Gentle daily activities such as walking in the house, gentle housework, and light school work that do not make symptoms worse. No sports activities.
Increased expression of ICAM-1 has been observed within the inflamed intestinal mucosa of people with ulcerative colitis, pouchitis and Crohns, where ICAM-1 over production correlated with disease activity. This suggests that ICAM-1 is a potential therapeutic target in the treatment of these diseases.Cannabinoid CB2 receptor agonists are found to decrease the induction of ICAM-1 and VCAM-1 surface expression in human brain tissues and primary human brain endothelial cells (BMVEC) exposed to various pro-inflammatory mediators.In 2014, an alliance among the Broad Institute, Amgen and Massachusetts General Hospital formed with the intention to "collect and analyze patient DNA samples to identify and further validate genetic targets. "In 2015, a meta-analysis on 938 IBD patients and 953 controls, IBD was significantly associated with having higher odds of vitamin D deficiency.Gram-positive bacteria present in the lumen could be associated with extending the time of relapse for ulcerative colitis.Bidirectional pathways between depression and IBD have been suggested  and psychological processes have been demonstrated to influence self-perceived physical and psychological health over time. IBD-disease activity may impact quality of life and over time may significantly affect individuals mental well-being, which may be related to the increased risk to develop anxiety and/or depression. On the other hand, psychological distress may also influence IBD activity.Higher rates of anxiety and depression are observed among those with IBD compared to healthy individuals, which correlated with disease severity. Moreover, anxiety and depression rates increase during active disease compared with inactive phases. See also
Inflammatory bowel disease-22
World Inflammatory Bowel Disease Day

References
External links
Inflammatory bowel disease at Curlie