In November 2017, Sanofi acknowledged that some participants were put at risk of severe dengue if they had no prior exposure to the infection; subsequently the Philippine government suspended the mass immunization program with the backing of the WHO which began a review of the safety data.Phase III trials in Latin America and Asia involved over 31,000 children between the ages of two and 14 years. In the first reports from the trials, vaccine  efficacy was 56.5% in the Asian study  and 64.7% in the Latin American study in patients who received at least one injection of the vaccine. Efficacy varied by serotype. In both trials vaccine reduced by about 80% the number of severe dengue cases. An analysis of both the Latin American and Asian studies at the 3rd year of follow-up showed that the efficacy of the vaccine was 65.6% in preventing hospitalization in children older than nine years of age, but considerably greater (81.9%) for children who were seropositive (indicating previous dengue infection) at baseline. The vaccination series consists of three injections at 0, 6 and 12 months. The vaccine was approved in Mexico, Philippines, and Brazil in December 2015, and in El Salvador, Costa Rica, Paraguay, Guatemala, Peru, Indonesia, Thailand and Singapore in 2016. Tradenamed Dengvaxia, it is approved for use for those aged nine and older and can prevent all four serotypes.
Patrice ONeal: American standup comedian who had on several occasions mentioned his appreciation for golden showers, even stating that his girlfriend noticing that his urine tasted like "birthday cake" is how he came to find out that he suffered from diabetes. Annie Sprinkle: an American porn actress, later turned sex educator and advocate for female sexual enjoyment. Her stage name is derived from her obsession with fluids. Troughman: an Australian noted in the Sydney media for lying down in urinal troughs at Sydney Mardi Gras parties and other events. Ian Watkins: the former lead singer for the Welsh rock band Lostprophets. Convicted in December 2013 of numerous child sex abuse charges, which include urolagnia. See also
Urination and sexual activity
Urophagia

References
External links
 Media related to Urolagnia at Wikimedia Commons