Online Mendelian Inheritance in Man (OMIM): 106210 AN
Online Mendelian Inheritance in Man (OMIM): 106220 Aniridia and absent patella
Online Mendelian Inheritance in Man (OMIM): 106230 Aniridia, microcornea, and  spontaneously reabsorbed cataract
Online Mendelian Inheritance in Man (OMIM): 206700 Aniridia, cerebellar ataxia, and mental deficiency (Gillespie syndrome)

Mutational analysis
Molecular (DNA) testing for PAX6 gene mutations (by sequencing of the entire coding region and deletion/duplication analysis) is available for isolated aniridia and the Gillespie syndrome. For the WAGR syndrome, high-resolution cytogenetic analysis and fluorescence in situ hybridization (FISH) can be utilized to identify deletions within chromosome band 11p13, where both the PAX6 and WT1 genes are located. Symptoms
Aniridia can cause many symptoms, such as:

Poor vision (not always present)
More sensitivity to light
Fast, uncontrolled, shaking "to and from" eye movements (nystagmus)
Eyes dont line up (strabismus)

Treatment
In May 2018, the U.S. Food and Drug Administration approved the CustomFlex Artificial Iris, the first synthetic iris for use in adults and children with congenital aniridia or iris defects related to other conditions, such as albinism, traumatic injury, or surgical removal due to ocular melanoma. The artificial iris is a surgically implanted device made of thin, foldable, medical-grade silicone and is custom-sized and colored for each individual patient. The prosthetic iris is held in place by the anatomical structures of the eye or, if needed, by sutures. See also
WAGR syndrome
Scleral lenses

References
External links

GeneReviews/NCBI/NIH/UW entry on Aniridia
NCBI/Molecular diagnosis of aniridia
OMIM entries on Aniridia
GeneReviews/NIH/NCBI/UW entry on Wilms Tumor Overview
Mepivacaine  is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine. Mepivacaine became available in the United States in the 1960s. Mepivacaine is used in any infiltration and local anesthesia. It is supplied as the hydrochloride salt of the racemate, which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.Mepivacaine was originally synthesized in Sweden at the laboratory of Bofors Nobelkrut in 1956. References
External links
Mepivacaine at RxList