Bupropion also improves depression in bipolar disorder, with the efficacy and risk of affective switch being similar to other antidepressants.Bupropion has several features that distinguish it from other antidepressants: for instance, unlike the majority of antidepressants, it does not usually cause sexual dysfunction, and the occurrence of sexual side effects is not different from placebo. Bupropion treatment is not associated with weight gain; on the contrary, the majority of studies observed significant weight loss in bupropion-treated participants. Bupropion treatment also is not associated with the sleepiness that may be produced by other antidepressants. Bupropion is more effective than selective serotonin reuptake inhibitors (SSRIs) at improving symptoms of hypersomnia and fatigue in depressed patients. There appears to be a modest advantage for the SSRIs compared to bupropion in the treatment of depression with high anxiety; they are equivalent for depression with moderate or low anxiety.The addition of bupropion to a prescribed SSRI is a common strategy when people do not respond to the SSRI, and it is supported by clinical trials; however, it appears to be inferior to the addition of atypical antipsychotic aripiprazole. Smoking cessation
Prescribed as an aid for smoking cessation bupropion reduces the severity of craving for tobacco and withdrawal symptoms such as depressed
mood, irritability, difficulty concentrating, and increased appetite. Initially, bupropion slows the weight gain that often occurs in the first weeks after quitting smoking.
Research also shows that BDD is linked to high comorbidity and suicidality rates. Furthermore, it appears that Caucasian women show higher rates of body dissatisfaction than women of different ethnic backgrounds and societies.Socio-cultural models depict and emphasise the way thinness is valued, and beauty is obsessed over in Western culture, where advertising, marketing and social media play a large role in manicuring the ‘perfect’ body shape, size and look. The billions of dollars spent to sell products become causal factors of image conscious societies. Advertising also supports a specific ideal body image and creates a social capital in how individuals can acquire this ideal.However, personal attitudes towards the body do vary cross-culturally. Some of this variability can be accounted for due to factors such as food insecurity, poverty, climate, and fertility management. Cultural groups who experience food insecurity generally prefer larger-bodied women, however, many societies that have abundant access to food also value moderate to larger bodies. This is evident in a comparative study of body image, body perception, body satisfaction, body-related self-esteem and overall self-esteem of German, Guatemalan Q’eqchi’ and Colombian women. Unlike the German and Colombian women, the Q’eqchi’ women in this study live in the jungles of Guatemala and remain relatively removed from modern technology and secure food resources. The study found that the Q’eqchi’ women did not have notably higher body satisfaction when compared to the German or Colombian women.