Conversely, there is also fear that people may associate attitudes with higher-functioning people in minimally conscious state with people in persistent vegetative state, thus minimizing the value of their lives. Regulating therapeutic nihilism
Currently, risk aversion dominates the ethical landscape when research involves those with impaired decision-making abilities. Fears of therapeutic adventurism has led to a disproportionate view about the under-appreciation of potential benefits and an overstatement of risks. Thus, recognizing this distortion is important in order to calculate the right balance between protecting vulnerable populations that cannot provide autonomous consent and potentially restorative clinical trials. Notable examples
Jackie Wilson (June 9, 1934 – January 21, 1984) American soul and rock and roll singer who fell into a coma after collapsing on stage, woke up but quickly fell back into a coma for the rest of his life. Jan Grzebski (1942–2008), a Polish railroad worker who fell into a minimally conscious state in 1988 and woke up in 2007. Terry Wallis (1964-2022). This American man was in a coma for nearly a year after a truck accident, then a minimally conscious state for 19 years. Martin Pistorius (born 1975). Because of a mystery illness, the South African spent three years in a vegetative state, four years in a minimally conscious state, and five years unable to move anything other than his eyes (locked-in syndrome). In 1999, he fully awakened, and has since recovered to the point that he was able to become a web designer, developer, and author.
Lupus vasculitis is a complication of systemic lupus erythematosus in which the autoimmune response causes the deposition of immune complexes, such as rheumatoid factor, within the blood vessels. It may manifest in as high as 56% of lupus patients throughout their life, in contrast to antiphospholipid syndrome which has a prevalence of 15%. Vasculitis more often affects younger men. == References ==