Tendinopathy involves cellular apoptosis, matrix disorganization and neovascularization.Classic characteristics of "tendinosis" include degenerative changes in the collagenous matrix, hypercellularity, hypervascularity, and a lack of inflammatory cells which has challenged the original misnomer "tendinitis".Histological findings include granulation tissue, microrupture, degenerative changes, and there is no traditional inflammation. As a consequence, "lateral elbow tendinopathy or tendinosis" is used instead of "lateral epicondylitis".Examination of tennis elbow tissue reveals noninflammatory tissue, so the term "angiofibroblastic tendinosis" is used.Cultures from tendinopathic tendons contain an increased production of type III collagen.Longitudinal sonogram of the lateral elbow displays thickening and heterogeneity of the common extensor tendon that is consistent with tendinosis, as the ultrasound reveals calcifications, intrasubstance tears, and marked irregularity of the lateral epicondyle. Although the term "epicondylitis" is frequently used to describe this disorder, most histopathologic findings of studies have displayed no evidence of an acute, or a chronic inflammatory process. Histologic studies have demonstrated that this condition is the result of tendon degeneration, which causes normal tissue to be replaced by a disorganized arrangement of collagen. Therefore, the disorder is more appropriately referred to as "tendinosis" or "tendinopathy" rather than "tendinitis".Colour Doppler ultrasound reveals structural tendon changes, with vascularity and hypo-echoic areas that correspond to the areas of pain in the extensor origin.Load-induced non-rupture tendinopathy in humans is associated with an increase in the ratio of collagen III:I proteins, a shift from large to small diameter collagen fibrils, buckling of the collagen fascicles in the tendon extracellular matrix, and buckling of the tenocyte cells and their nuclei.
Shes not the brightest of the family, but shes bubbly and kind. Patton Chase (Ryan Pinkston) – The youngest of the children, and the shortest at 410". This is a source of amusement to the family and shame to the father, and the mother is often overly-nurturing. He takes growth hormones. He is girl-crazy and his typical line to girls (and, in one episode, a guy when he was pretending to be gay to avoid being pulverized) is, "Yes I am, you likey?." It usually works, but his sisters often find it disgusting. Episodes
See also
Arrested Development – in which Richter himself played a set of identical quintuplets. References
External links
Quintuplets at IMDb