Genetic studies of Sayyids of the Indian sub-continent
The authors of the study, the Y chromosomes of self-identified Syeds from the Indian sub-continent are no less diverse than those non-Syeds from the same regions, suggested that Syed status, rather than being strictly patrilineal, may have been passed through other routes.The paper, "Y chromosomes of self-identified Syeds from the Indian subcontinent", by Elise M. S. Belle, Saima Shah, Tudor Parfitt, and Mark G. Thomas showed that "self-identified Syeds had no less genetic diversity than those non-Syeds from the same regions, suggesting that there is no biological basis to the belief that self-identified Syeds in this part of the world share a recent common ancestry. However, self-identified men belonging to the ‘Islamic honorific lineages’ (Syeds, Hashemites, Quraysh and Ansari) show a greater genetic affinity to Arab populations—despite the geographic distance – than do their neighbouring populations from South Asia.In Northern India, 29 per cent of the Shia Muslim belong to haplogroup J. There are 18 per cent belonging mainly to haplogroup J2 and another 11 per cent belong to haplogroup J1, which both represent Middle Eastern lineages. J1 is exclusively Near Eastern. Southeast Asia
Most of the Alawi Sayyids who moved to Southeast Asia were descendants of Ali ibn Husayn Zayn al-Abidin, especially of Ba Alawi sada, many of which were descendants of migrants from Hadhramaut. Even though they are alleged descendants of Husayn, it is uncommon for the female Sayyids to be called Sayyidah; they are more commonly called Sharifah.
Stiff skin syndrome (also known as "Congenital fascial dystrophy") is a cutaneous condition characterized by ‘rock hard’ induration, thickening of the skin and subcutaneous tissues, limited joint mobility, and mild hypertrichosis in infancy or early childhood. Immunologic abnormalities or vascular hyperactivity are not present in patients.Not much is known about it, cause or treatment, and further investigation is required, as it has only been reported 41 times throughout history. Genetics
This condition is associated with mutations in the Fibrillin 1 (FBN1) gene. Diagnosis
Differential diagnosis
Other conditions associated with mutations in this gene include acromicric dysplasia, Marfan syndrome and its variant Marfanoid–progeroid–lipodystrophy syndrome, autosomal dominant Weill-Marchesani syndrome, isolated ectopia lentis, MASS phenotype, and Shprintzen-Goldberg syndrome. See also
Scleroderma
Self-healing papular mucinosis
List of cutaneous conditions

References


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