It is simply a nuisance for people to inject whenever they eat carbohydrate or have a high blood glucose reading. It is dangerous in case of mistake (most especially too much insulin). Types
Medical preparations of insulin are never just insulin in water (with nothing else). Clinical insulins are mixtures of insulin plus other substances including preservatives. These prevent the protein from spoiling or denaturing too rapidly, delay absorption of the insulin, adjust the pH of the solution to reduce reactions at the injection site, and so on.Slight variations of the human insulin molecule are called insulin analogues, (technically "insulin receptor ligands") so named because they are not technically insulin, rather they are analogues which retain the hormones glucose management functionality. They have absorption and activity characteristics not currently possible with subcutaneously injected insulin proper. They are either absorbed rapidly in an attempt to mimic real beta cell insulin (as with insulin lispro, insulin aspart, and insulin glulisine), or steadily absorbed after injection instead of having a peak followed by a more or less rapid decline in insulin action (as with insulin detemir and insulin glargine), all while retaining insulins glucose-lowering action in the human body.
Finally, a biopsy of a skin lesion can be performed to rule out any other causes.The immunohistochemical features are very similar to those presented in mycosis fungoides except for the following differences:
More monotonous cellular infiltrates (large, clustered atypical pagetoid cells) in Sézary syndrome
Sometimes absent epidermotropism
Increased lymph node involvement with infiltrates of Sézary syndrome. Treatment
Treatment typically includes some combination of photodynamic therapy, radiation therapy, chemotherapy, and biologic therapy.Treatments are often used in combination with phototherapy and chemotherapy, though pure chemotherapy is rarely used today. No single treatment type has revealed clear-cut benefits in comparison to others, treatment for all cases remains problematic. Radiation therapy
A number of types of radiation therapy may be used including total skin electron therapy. While this therapy does not generally result in systemic toxic effects it can produce side effects involving the skin. It is only available at a few institutions. Chemotherapy
Romidepsin, vorinostat and a few others are a second-line drug for cutaneous T-cell lymphoma. Mogamulizumab has been approved in Japan and the United States. Epidemiology
In the Western population, there are around 3 cases of Sézary syndrome per 1,000,000 people. Sézary disease is more common in males with a ratio of 2:1, and the mean age of diagnosis is between 55 and 60 years of age. See also
List of cutaneous conditions

References
External links

Sezary Syndrome lymphoma information