Cabergoline, sold under the brand name Dostinex among others, is a dopaminergic medication used in the treatment of high prolactin levels, prolactinomas, Parkinsons disease, and for other indications. It is taken by mouth. Cabergoline is an ergot derivative and a potent dopamine D2 receptor agonist.Cabergoline was patented in 1980 and approved for medical use in 1993. Medical uses
Lactation suppression
Hyperprolactinemia
Adjunctive therapy of prolactin-producing pituitary gland tumors (prolactinomas);
Monotherapy of Parkinsons disease in the early phase;
Combination therapy, together with levodopa and a decarboxylase inhibitor such as carbidopa, in progressive-phase Parkinsons disease;
In some countries also: ablactation and dysfunctions associated with hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, nonpuerperal mastitis and galactorrhea);
Treatment of uterine fibroids. Adjunctive therapy of acromegaly, cabergoline has low efficacy in suppressing growth hormone levels and is highly efficient in suppressing hyperprolactinemia that is present in 20-30% of acromegaly cases; growth hormone and prolactin are similar structurally and have similar effects in many target tissues, therefore targeting prolactin may help symptoms when growth hormone secretion can not be sufficiently controlled by other methods;Cabergoline is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine, though in pregnancy bromocriptine is often still chosen since there is less data on safety in pregnancy for cabergoline. Off-label
It has at times been used as an adjunct to SSRI antidepressants as there is some evidence that it counteracts certain side effects of those drugs, such as reduced libido and anorgasmia.
Zar may refer to:

Places
Zar, Armenia
Zar, Azerbaijan
Žár, Czech Republic
Zar, Iran, in Markazi Province
Zeraq, or Zar, Hamadan Province, Iran
Żar, Łódź Voivodeship, Poland
Żar (mountain), in Poland
Žar Mountain, a mountain range in Kosovo
South African Republic (Dutch: Zuid-Afrikaanse Republiek)

People
Surname
Chet Zar (born 1967), American artist; son of James Zar
Heather Zar (born ? ), South African pediatrician, respiratory specialist, writer, and professor
Ibn Abi Zar (died between 1310 and 1320), Moroccan historian and poet; presumed author of the medieval history of Morocco, Rawd al-Qirtas
James Zar (1941–2015), American artist; father of Chet Zar
Jerrold Zar (born 1941), American biologist and professor
Lwi Zar (born 1976), Burmese politician
Mordechai Zar (1914–1982), Israeli politician
Moshe Zar (born 1938), Israeli settlement leader and religious Zionist
Paul Zar (born 1967), American bobsledder and Olympic competitor
Pe Thein Zar (1943–2018), Burmese-born Australian student leader, lawyer, revolutionary and freedom fighter, and writer
Rose Zar (1922–2001), a Polish Holocaust survivor, human rights activist, and author
Sarah Zar (born ? ), American visual and performance artist, musician, songwriter, and writer

Given name
Zar Wali Khan (born 1953), Pakistani Islamic scholar
Zar Gul Khan (fl. 2017), Pakistani politician
Zar Lawrence (born 1982), New Zealand rugby player
Zar Randeri (pen name of Bharucha Hasim bin Yusuf; 1887–? ), Indian Gujarati poet and translator
Zar Zar Myint (born 1993), Burmese footballer
Zar Zari Zar Baksh (fl.c.