This is also a reason why mens acne tends to remain a problem for longer once its developed. Acne in general is hereditary from parents to child, so genetics play a factor as well. People who already have acne and have a problematic skin type that tends to create clogged pores are more likely to develop acne mechanica as well. Research Directions
Although not exactly having to do with acne mechanica and the heat or pressure stressors that cause it, there is still not a lot of research relating to different organs health relating to acne appearing on different areas of the body and face. A correlation between the two could be explored in future studies. See also
List of cutaneous conditions


== References ==
Genetics
This condition is caused by mutations in the WFS1 gene, these mutations are inherited in an autosomal dominant manner, meaning that for a person to exhibit the symptoms of Wolfram-like syndrome, they must have at least one copy of the mutation that is responsible for the phenotype of the disorder, this mutation is usually inherited, but there are cases where the mutation is de novo, meaning that it wasnt inherited from either parent, but rather the result of a spontaneous error in cell division.This gene encodes a protein called wolframin, the mutations typically found in people with this condition cause the production of a protein that is either absent or has little to no function at all.Mutations in this gene are also associated with other disorders affecting vision or hearing, (aside from Wolfram syndrome) such as non-syndromic autosomal dominant deafness type 6., isolated autosomal dominant congenital cataract, etc. In rare cases, a mutation in the CDK13 gene instead of the WFS1 gene is responsible for the disorder, this genetic mutation has only been described in 3 affected children belonging to a consanguineous Pakistani family who, in addition to the typical symptoms of the disorder, also had anomalies affecting the gastrointestinal tract, congenital heart defects, and clinodactyly.