As of 2019, ivermectin tablets (Stromectol) in the United States were the least expensive treatment option for lice in children at approximately US$9.30, while Sklice, an ivermectin lotion, cost around US$300 for 120 mL (4 US fl oz).As of 2019, the cost effectiveness of treating scabies and lice with ivermectin has not been studied. Brand names
It is sold under the brand names Heartgard, Sklice and Stromectol in the United States, Ivomec worldwide by Merial Animal Health, Mectizan in Canada by Merck, Iver-DT in Nepal by Alive Pharmaceutical and Ivexterm in Mexico by Valeant Pharmaceuticals International. In Southeast Asian countries, it is marketed by Delta Pharma Ltd. under the trade name Scabo 6. The formulation for rosacea treatment is sold under the brand name Soolantra. While in development, it was assigned the code MK-933 by Merck. Research
Parasitic disease
Ivermectin has been researched in laboratory animals, as a potential treatment for trichinosis. Tropical diseases
As of 2016 ivermectin was studied as a potential antiviral agent against chikungunya and yellow fever. In chikungunya, ivermectin showed a wide in vitro safety margin as an antiviral.Ivermectin is also of interest in the prevention of malaria, as it is toxic to both the malaria plasmodium itself and the mosquitos that carry it. A direct effect on malaria parasites could not be shown in an experimental infection of volunteers with Plasmodium falciparum.
The superior pubic ligament connects together the two pubic bones superiorly, extending laterally as far as the pubic tubercles. The inferior ligament in the pubic arch is also known as the arcuate pubic ligament or subpubic ligament; it is a thick, triangular arch of ligamentous fibers, connecting together the two pubic bones below, and forming the upper boundary of the pubic arch. Above, it is blended with the interpubic fibrocartilaginous lamina; laterally, it is attached to the inferior rami of the pubic bones; below, it is free, and is separated from the fascia of the urogenital diaphragm by an opening through which the deep dorsal vein of the penis passes into the pelvis. Fibrocartilage
Fibrocartilage is composed of small, chained bundles of thick, clearly defined, type I collagen fibers. This fibrous connective tissue bundles have cartilage cells between them; these cells to a certain extent resemble tendon cells. The collagenous fibers are usually placed in an orderly arrangement parallel to tension on the tissue. It has a low content of glycosaminoglycans (2% of dry weight). Glycosaminoglycans are long, unbranched polysaccharides (relatively complex carbohydrates) consisting of repeating disaccharide units. Fibrocartilage does not have a surrounding perichondrium. Perichondrium surrounds the cartilage of developing bone; it has a layer of dense, irregular connective tissue and functions in the growth and repair of cartilage. Hyaline cartilage
Hyaline cartilage is the white, shiny gristle at the end of long bones. This cartilage has poor healing potential, and efforts to induce it to repair itself frequently end up with a similar, but poorer fibrocartilage.