Burning feet syndrome, also known as Grierson-Gopalan syndrome, is a medical condition that causes severe burning and aching of the feet, hyperesthesia, and vasomotor changes of the feet that lead to excessive sweating. It can even affect the eyes, causing scotoma and amblyopia. The condition occurs more frequently in women, and usually manifests itself when a person is between twenty and forty years old. Presentation
The burning heat is usually limited to the soles of the feet, but may extend up to the ankles or lower legs of some patients. The burning can sometimes be accompanied by feelings of pins and needles or tingling in these regions. Nighttime is when almost all people with this syndrome report the heat symptoms being the worst, with the condition getting better as morning comes. Those who have psychosomatic disorders sometimes display psychological symptoms along with the burning of feet associated with the syndrome. For most, there is no redness of the skin of their feet during the heat sensations, and almost never is there accompanying tenderness along with it. Causes
Burning feet syndrome can be inherited, or it can be caused by pressure being put on the nerves. Links also exist between this syndrome and diseases such as hypothyroidism, diabetes mellitus, and rheumatoid arthritis; links are also believed to exist between this syndrome and Zinc deficiency. It is also linked to vitamin B (specifically pantothenic acid) deficiencies and kidney failure. It seems to be a small fiber neuropathy. Diagnosis
Diagnosis is mainly clinical.
This in turn affects the human immune systems ability to fight infection, in total there are 9 possible types of this condition. Diagnosis
Chronic mucocutaneous candidiasis can be diagnosed in an affected individual via the following methods/tests:

Types
Treatment
Management for an individual with chronic mucocutaneous candidiasis consists of the following (relapse occurs once treatment is ceased, in many cases):
Systemic anti-fungal therapy (e.g., Fluconazole)
Transfer factor
Combination therapy
Screening (annually)

See also
Candidiasis
List of cutaneous conditions

Notes
^  Indicates 9 references to specific, numbered pages in the Online Mendelian Inheritance in Man database. References
Further reading
Kauffman, Carol A.; Pappas, Peter G.; Sobel, Jack D.; Dismukes, William E. (2011). Essentials of Clinical Mycology. Springer Science & Business Media. ISBN 9781441966407. Retrieved 9 June 2017. Ostler, H. Bruce (2004). Diseases of the Eye and Skin: A Color Atlas. Lippincott Williams & Wilkins. ISBN 9780781749992. Retrieved 9 June 2017. == External links ==