This is associated with increased pressure in the eye. Not all people with primary open-angle glaucoma have eye pressure that is elevated beyond normal, but decreasing the eye pressure further has been shown to stop progression even in these cases. The increased pressure is caused by trabecular meshwork blockage. Because the microscopic passageways are blocked, the pressure builds up in the eye and causes imperceptible very gradual vision loss. Peripheral vision is affected first, but eventually the entire vision will be lost if not treated. Diagnosis is made by looking for cupping of the optic nerve. Prostaglandin agonists work by opening uveoscleral passageways. Beta-blockers, such as timolol, work by decreasing aqueous formation. Carbonic anhydrase inhibitors decrease bicarbonate formation from ciliary processes in the eye, thus decreasing the formation of aqueous humor. Parasympathetic analogs are drugs that work on the trabecular outflow by opening up the passageway and constricting the pupil. Alpha 2 agonists (brimonidine, apraclonidine) both decrease fluid production (via inhibition of AC) and increase drainage. Developmental glaucoma
Developmental glaucoma (Q15.0)

Primary congenital glaucoma
Infantile glaucoma
Glaucoma associated with hereditary or familial diseases

Secondary glaucoma
Secondary glaucoma (H40.3-H40.6)

Inflammatory glaucomaUveitis of all types
Fuchs heterochromic iridocyclitisPhacogenic glaucomaAngle-closure glaucoma with mature cataract
Phacoanaphylactic glaucoma secondary to rupture of lens capsule
Phacolytic glaucoma due to phacotoxic meshwork blockage
Subluxation of lensGlaucoma secondary to intraocular hemorrhageHyphema
Hemolytic glaucoma, also known as erythroclastic glaucomaTraumatic glaucomaAngle recession glaucoma: Traumatic recession on anterior chamber angle
Postsurgical glaucomaAphakic pupillary block
Ciliary block glaucomaNeovascular glaucoma (see below for more details)
Drug-induced glaucomaCorticosteroid induced glaucoma
Alpha-chymotrypsin glaucoma.
Trichoepithelioma is a neoplasm of the adnexa of the skin. Its appearance is similar to basal cell carcinoma. One form has been mapped to chromosome 9p21. Types
Trichoepitheliomas may be divided into the following types:: 672 
Multiple familial trichoepithelioma
Solitary trichoepithelioma
Desmoplastic trichoepithelioma

Pathology
Trichoepitheliomas consists of nests of basaloid cells, with palisading. They lack the myxoid stroma and artefactual clefting seen in basal cell carcinoma. Mitoses are uncommon when compared to basal cell carcinoma. Diagnosis
Trichoepiteliomas often contain Merkel cells; an immunostain for CK20 can be used to demonstrate this. See also
Trichoblastoma
Pilomatricoma
CYLD cutaneous syndrome
List of cutaneous conditions
List of cutaneous neoplasms associated with systemic syndromes

References


== External links ==