A decrease in hippocampal volume is one of the factors linked to the development of the disease. However, there still remains the problem of increasing motivation for, and maintaining participation in physical activity. Supervised sessions are recommended. In the UK healthy eating advice is offered alongside exercise programs.An inadequate diet is often found in schizophrenia, and associated vitamin deficiencies including those of folate, and vitamin D are linked to the risk factors for the development of schizophrenia and for early death including heart disease. Those with schizophrenia possibly have the worst diet of all the mental disorders. Lower levels of folate and vitamin D have been noted as significantly lower in first episode psychosis. The use of supplemental folate is recommended. A zinc deficiency has also been noted. Vitamin B12 is also often deficient and this is linked to worse symptoms. Supplementation with B vitamins has been shown to significantly improve symptoms, and to put in reverse some of the cognitive deficits. It is also suggested that the noted dysfunction in gut microbiota might benefit from the use of probiotics. Prognosis
Schizophrenia has great human and economic costs. It decreases life expectancy by between 20 and 28 years. This is primarily because of its association with heart disease, diabetes, obesity, poor diet, a sedentary lifestyle, and smoking, with an increased rate of suicide playing a lesser role. Side effects of antipsychotics may also increase the risk.Almost 40% of those with schizophrenia die from complications of cardiovascular disease which is seen to be increasingly associated.
Such a procedure is unnecessary, given that situs inversus rarely causes any additional symptoms. No treatment, medical or surgical, is prescribed for situs inversus patients, with medical professionals instead treating any other symptoms the patient may have with awareness of the unique anatomy of the patient. Epidemiology
Situs inversus is very rare, affecting 0.01% of the population. This is equivalent to 1 in 10,000 people. History
Dextrocardia (the heart being located on the right side of the thorax) was seen and drawn by Leonardo da Vinci, and then recognised by Marco Aurelio Severino in 1643. Situs inversus was first described more than a century later by Matthew Baillie. Etymology
The term situs inversus is a short form of the Latin phrase situs inversus viscerum, meaning "inverted position of the internal organs". Notable cases
Notable individuals with documented cases of situs inversus include:

Enrique Iglesias, a Spanish singer, songwriter, actor and record producer. Catherine OHara, Canadian-American actress, writer and comedian. Randy Foye, an American basketball player in the NBA. He has suffered no discernible complications, and the condition is not expected to affect his career as a professional athlete, as all his organs are in reverse. Ginggaew Lorsoongnern, a Thai convict executed by firing squad. Her condition was discovered after she was shot in the left side of her chest and survived. After waking up in the morgue she was taken back and executed. Tim Miller, director of the Ashtanga Yoga Center in Carlsbad, California.