In terms of steroid strength, it is more potent than hydrocortisone, and less potent than dexamethasone.Some low-quality evidence suggests the use of mometasone for symptomatic improvement in children with adenoid hypertrophy.Mometasone is used to alleviate inflammation and itchiness in skin conditions that respond to treatment with glucocorticoids such as psoriasis and atopic dermatitis.Nasal mometasone is used in adults (including the elderly) and children over two years of age, to diminish the symptoms of hay fever (seasonal allergic rhinitis) and other allergies (perennial rhinitis), including nasal congestion, discharge, pruritus, and sneezing and to treat nasal polyps.It is not useful for the common cold. Asthma
Mometasone furoate can be used with formoterol for the treatment of asthma, due to its anti-inflammatory properties. Contraindications
People should not use inhaled mometasone or mometasone nasal spray if:

glaucoma or cataracts
hypersensitivity or allergic to any ingredient in mometasoneThose who are using mometasone nasal or inhaled for a long period of time (e.g. more than three months) should get regular eye exams to check for glaucoma and cataracts and should take precautions to avoid infections such as taking a vitamin D supplement, staying away from those with an infection (chickenpox, measles, colds or flu, COVID-19), washing foods, hand washing and calling a family doctor at the first sign of a severe infection. People should not use mometasone topical (skin cream) if:

hypersensitive or allergic to any ingredient in the skin creamMometasone furoate is in class C in terms of safety while use during pregnancy. Therefore, its risks to the baby cannot be ruled out.
Therefore, the use in pregnancy is not recommended. Side effects
The nasal spray form of mometasone may cause the following side effects:

headache
Viral upper respiratory infections
sore throat
nose bleeds
cough
muscle and joint painSerious side effects include: Thrush (fungal infection in the nose or throat), slow wound healing, eye problems such as glaucoma or cataracts, weakened immune system (immunodeficiency) which causes an increased susceptibility to infections and adrenal insufficiency. The inhaled form of mometasone for asthma may cause the following side effects

headache
stuffy or runny nose
dry throat
swelling of nose, throat and sinuses
flu like symptoms
painful menstrual periodsSerious side effects may include: allergic reactions (anaphylaxis), increased risk of osteoporosis, glaucoma and cataracts, thrush in the mouth or throat, growth retardation in children, bronchospasms, adrenal insufficiency and weakened immune system which causes an increased susceptibility to infections. The topical (skin cream) version may cause:

burning and itching at the application site
acne
changes in skin color
dryness at application site
skin soresThe only serious side effect that is known with mometasone topical is adrenal insufficiency. Pharmacology
Pharmacodynamics
Mometasone furoate reduces inflammation by causing several effects:
Reversing the activation of inflammatory proteins
Activating the secretion of anti-inflammatory proteins
Stabilizing cell membranes
Decreasing the influx of inflammatory cellsIn addition to the glucocorticoid properties of mometasone furoate, it is a very potent agonist of the progesterone receptor as well as a partial agonist of the mineralocorticoid receptor. Mechanism of action
Mometasone, like other corticosteroids, possesses anti-inflammatory, antipruritic, and vasoconstrictive properties. For allergies, corticosteroids reduce the allergic reactions in various types of cells (mastocytes and eosinophils) that are responsible for allergic reactions.