Propranolol
Bucindolol (has additional α1-blocking activity)
Carteolol
Carvedilol (has additional α1-blocking activity)
Labetalol (has intrinsic sympathomimetic activity and additional α1-blocking activity)
Nadolol
Oxprenolol (has intrinsic sympathomimetic activity)
Penbutolol (has intrinsic sympathomimetic activity)
Pindolol (has intrinsic sympathomimetic activity)
Sotalol (not considered a "typical beta blocker")
Timolol

β1-selective agents
β1-selective beta blockers are also known as cardioselective beta blockers. Pharmacologically, the beta-blockade of the B1 receptors in the heart will act on cAMP. The function of cAMP as a second messenger in the cardiac cell is that it phosphorylates the LTCC and the ryanodine receptor to increase intracellular calcium levels and cause contraction. Beta-blockade of the B1 receptor will inhibit cAMP from phosphorylating, and it will decrease the ionotrophic and chronotropic effect. Note that drugs may be cardioselective, or act on B1 receptors in the heart only, but still have instrinsic sympathomimetic activity. Acebutolol (has intrinsic sympathomimetic activity, ISA)
Atenolol
Betaxolol
Bisoprolol
Celiprolol (has intrinsic sympathomimetic activity)
Metoprolol
Nebivolol
EsmololNebivolol and Bisoprolol are the most β1 cardioselective beta blockers.
In 1964, James Black synthesized the first clinically significant beta blockers—propranolol and pronethalol; it revolutionized the medical management of angina pectoris and is considered by many to be one of the most important contributions to clinical medicine and pharmacology of the 20th century.For the treatment of primary hypertension, meta-analyses of studies which mostly used atenolol have shown that although beta blockers are more effective than placebo in preventing stroke and total cardiovascular events, they are not as effective as diuretics, medications inhibiting the renin–angiotensin system (e.g., ACE inhibitors), or calcium channel blockers. Medical uses
Large differences exist in the pharmacology of agents within the class, thus not all beta blockers are used for all indications listed below.