Unfortunately, there are currently no drug treatments that decrease these patients risk of dying in the longer term, at 3–12 months and beyond.Weak evidence suggests milk thistle extracts may improve survival in alcoholic liver disease and improve certain liver tests (serum bilirubin and GGT) without causing side effects, but a firm recommendation cannot be made for or against milk thistle without further study. The modified Maddreys discriminant function may be used to evaluate the severity and prognosis in alcoholic hepatitis and evaluates the efficacy of using alcoholic hepatitis corticosteroid treatment. Autoimmune hepatitis
Autoimmune hepatitis is commonly treated by immunosuppressants such as the corticosteroids prednisone or prednisolone, the active version of prednisolone that does not require liver synthesis, either alone or in combination with azathioprine, and some have suggested the combination therapy is preferred to allow for lower doses of corticosteroids to reduce associated side effects, although the result of treatment efficacy is comparative.Treatment of autoimmune hepatitis consists of two phases; an initial and maintenance phase. The initial phase consists of higher doses of corticosteroids which are tapered down over a number of weeks to a lower dose. If used in combination, azathioprine is given during the initial phase as well. Once the initial phase has been completed, a maintenance phase that consists of lower dose corticosteroids, and in combination therapy, azathioprine until liver blood markers are normalized. Treatment results in 66-91% of patients achieving normal liver test values in two years, with the average being 22 months.
These populations include people who are:

Intravenous drug users (past or current)
Intranasal illicit drug users
HIV-positive
Men who have sex with men
Incarcerated, or who have been in the past
On long-term hemodialysis, or who have been in the past
Recipients of tattoos in an "unregulated setting"
Recipients of blood products or organs prior to 1992 in the United States
Adults in the United States born between 1945 and 1965
Born to HCV-positive mothers
Pregnant, and engaging in high-risk behaviors
Workers in a healthcare setting who have had a needlestick injury
Blood or organ donors. Sex workersFor people in the groups above whose exposure is ongoing, screening should be periodic, though there is no set optimal screening interval. The AASLD recommends screening men who have sex with men who are HIV-positive annually. People born in the US between 1945 and 1965 should be screened once (unless they have other exposure risks).Screening consists of a blood test that detects anti-hepatitis C virus antibody. If anti-hepatitis C virus antibody is present, a confirmatory test to detect HCV RNA indicates chronic disease. Hepatitis D
The CDC, WHO, USPSTF, AASLD, and ACOG recommend screening people at high risk for hepatitis D infection. These populations include people who are:

Intravenous drug users (past or current)
Intranasal illicit drug users
Incarcerated, or who have been in the past
Workers in a healthcare setting who have had a needlestick injury
Blood or organ donors. Sex workersHepatitis D is extremely rare. Symptoms include chronic diarrhea, anal and intestinal blisters, purple urine, and burnt popcorn scented breath. Screening consists of a blood test that detects the anti-hepitits D virus antibbody.