Before 24 weeks PROM occurs in fewer than 1% of pregnancies. Prognosis is primarily determined by complications related to prematurity such as necrotizing enterocolitis, intraventricular hemorrhage, and cerebral palsy. Signs and symptoms
Most women will experience a painless leakage of fluid out of the vagina. They may notice either a distinct "gush" or a steady flow of small amounts of watery fluid in the absence of steady uterine contractions. Loss of fluid may be associated with the baby becoming easier to feel through the belly (due to the loss of the surrounding fluid), decreased uterine size, or meconium (fetal stool) seen in the fluid. Risk factors
The cause of PROM is not clearly understood, but the following are risk factors that increase the chance of it occurring. In many cases, however, no risk factor is identified. Infections: urinary tract infection, sexually transmitted diseases, lower genital tract infections (e.g. bacterial vaginosis), infections within the amniotic sac membranes (chorioamnionitis)
Tobacco use during pregnancy
Illicit drug use during pregnancy
Having had PROM or preterm delivery in previous pregnancies
Polyhydramnios: too much amniotic fluid 
Multiple gestation: being pregnant with two or more fetuses at one time
Having had episodes of bleeding anytime during the pregnancy
Invasive procedures (e.g. amniocentesis)
Nutritional deficits
Cervical insufficiency: having a short or prematurely dilated cervix during pregnancy
Low socioeconomic status
Being underweight

Pathophysiology
Weak membranes
Fetal membranes likely break because they become weak and fragile. This weakening is a normal process that typically happens at term as the body prepares for labor and delivery. However, this can be a problem when it occurs before 37 weeks (preterm).
Such challenges can appear in one or several sensory systems of the somatosensory system, vestibular system, proprioceptive system, interoceptive system, auditory system, visual system, olfactory system, and gustatory system.While many people can present one or two symptoms, sensory processing disorder has to have a clear functional impact on the persons life:
Signs of over-responsivity, including, for example, dislike of textures such as those found in fabrics, foods, grooming products or other materials found in daily living, to which most people would not react, and serious discomfort, sickness or threat induced by normal sounds, lights, ambient temperature, movements, smells, tastes, or even inner sensations such as heartbeat.Signs of under-responsivity, including sluggishness and lack of responsiveness. Sensory cravings, including, for example, fidgeting, impulsiveness, and/or seeking or making loud, disturbing noises; and sensorimotor-based problems, including slow and uncoordinated movements or poor handwriting. Sensory discrimination problems, which might manifest themselves in behaviors such as things constantly dropped.Symptoms may vary according to the disorders type and subtype present. Relationship to other disorders
Sensory integration and processing difficulties can be a feature of a number of disorders, including anxiety problems, attention deficit hyperactivity disorder (ADHD), food intolerances, behavioral disorders, and particularly, autism spectrum disorders.