There is not enough evidence of antihistamine efficacy as an add-on therapy with nasal steroids in the management of intermittent or persistent allergic rhinitis in children, so its adverse effects and additional costs must be considered.Ophthalmic antihistamines (such as azelastine in eye drop form and ketotifen) are used for conjunctivitis, while intranasal forms are used mainly for sneezing, rhinorrhea, and nasal pruritus.Antihistamine drugs can have undesirable side-effects, the most notable one being drowsiness in the case of oral antihistamine tablets. First-generation antihistamine drugs such as diphenhydramine cause drowsiness, while second- and third-generation antihistamines such as cetirizine and loratadine are less likely to.Pseudoephedrine is also indicated for vasomotor rhinitis. It is used only when nasal congestion is present and can be used with antihistamines. In the United States, oral decongestants containing pseudoephedrine must be purchased behind the pharmacy counter in an effort to prevent the manufacturing of methamphetamine. Desloratadine/pseudoephedrine can also be used for this condition

Steroids
Intranasal corticosteroids are used to control symptoms associated with sneezing, rhinorrhea, itching, and nasal congestion. Steroid nasal sprays are effective and safe, and may be effective without oral antihistamines.
Platybasia is a spinal disease of a malformed relationship between the occipital bone and cervical spine. It may be caused by Pagets disease. Platybasia is also a feature of Gorlin-Goltz syndrome, commonly known as basal cell nevus syndrome. It may be developmental in origin or due to softening of the skull base bone, allowing it to be pushed upward. The developmental variant is the result of a wider angle between the skull base of the frontal or anterior fossa and the clivus, which defines the anterior wall of the posterior fossa. It is sometimes associated with other congenital abnormalities of the bone structure, such as fusion of the first cervical vertebrae to the skull atlas assimilation. Further reading
Pearce JM (2007). "Platybasia and basilar invagination". Eur. Neurol. 58 (1): 62–4. doi:10.1159/000102172. PMID 17483591. == External links ==