GB patent 1472793, John B Glen & Roger James, "Pharmaceutical Compositions", published 1977-05-04,  assigned to Imperial Chemical Industries Ltd
interphalangeal joints of the fingers) and there can be associated tenosynovitis, but there is no erosion or deformation in the long term. Diarrhea may also occur. Mechanism
Immune complexes are thought to cause blood vessel damage, attracting neutrophils into the skin and synovium in BADAS. These antigen-antibody complexes are thought to be caused by excessive exposure to bacterial antigens (especially peptidoglycans). Bacterial overgrowth appears to be a frequent underlying condition. These antibodies possibly stimulate migration of neutrophils into the affected joints and skin. The effect of antibacterial therapy supports a role for bacteria in the disease mechanism (pathogenesis). Diagnosis
A diagnosis of this syndrome is made when an individual has the constellation of the characteristic recurrent neutrophilic dermatosis, flu-like symptoms, arthralgias or arthritis, and myalgias in the setting of a pathology of the bowels that is not best explained by another diagnosis. See also
Sweets syndrome-like dermatosis
List of cutaneous conditions


== References ==