It can be given subcutaneously, intramuscularly, intravenously, or, when a tablet is crushed, in the conjunctiva of the eye. The oral route is ineffective, as apomorphine cannot cross the blood–brain barrier fast enough, and blood levels dont reach a high enough concentration to stimulate the chemoreceptor trigger zone. It can remove around 40–60% of the contents in the stomach.One of the reasons apomorphine is a preferred drug is its reversibility: in cases of prolonged vomiting, the apomorphine can be reversed with dopamine antagonists like the phenothiazines (for example, acepromazine). Giving apomorphine after giving acepromazine, however, will no longer stimulate vomiting, because apomorphines target receptors are already occupied. An animal who undergoes severe respiratory depression due to apomorphine can be treated with naloxone.Apomorphine does not work in cats, who have too few dopamine receptors. See also
Apomorphine (data page)
Propylnorapomorphine

References
External links
"Apomorphine". Drug Information Portal. U.S. National Library of Medicine.
Rheumatoid disease did not develop in this latter variant.Today, a primarily auto-immune cause predominates literature with speculation that IH may be an inherited conditionOn the basis that IH is periodic in its presentation, early researchers proposed links with malaria where symptoms are also cyclical, even though the two have different duration cycles. Treatment with quinine (and arsenic) compounds were trialled with little benefit. Links to other infectious disease have also been posited over the years. These included Brucella, gonorrhoea, and syphilis.Adrenaline injections, mercury, various hormone treatments (ovarian extracts, growth hormone, stilboestrol), and ergotamine tartrate are among other treatments at some time used without significant or long-term benefit. Physiotherapy, surgery, exclusion diets (following allergen testing) have similarly shown no particular success in early reports of IH. References


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