The spotters ability to see what radar cannot is especially important as distance from the radar site increases, because the radar beam becomes progressively higher in altitude further away from the radar, chiefly due to curvature of Earth, and the beam also spreads out. Visual evidence
Storm spotters are trained to discern whether or not a storm seen from a distance is a supercell. They typically look to its rear, the main region of updraft and inflow. Under that updraft is a rain-free base, and the next step of tornadogenesis is the formation of a rotating wall cloud. The vast majority of intense tornadoes occur with a wall cloud on the backside of a supercell.Evidence of a supercell is based on the storms shape and structure, and cloud tower features such as a hard and vigorous updraft tower, a persistent, large overshooting top, a hard anvil (especially when backsheared against strong upper level winds), and a corkscrew look or striations. Under the storm and closer to where most tornadoes are found, evidence of a supercell and the likelihood of a tornado includes inflow bands (particularly when curved) such as a "beaver tail", and other clues such as strength of inflow, warmth and moistness of inflow air, how outflow- or inflow-dominant a storm appears, and how far is the front flank precipitation core from the wall cloud.
Methazolamide (trade name Neptazane) is a potent carbonic anhydrase inhibitor. It is indicated in the treatment of increased intraocular pressure (IOP) in chronic open-angle glaucoma and secondary glaucoma. Also it is used preoperatively in acute angle-closure (narrow-angle) glaucoma where lowering the IOP is desired before surgery. This drug has displayed teratogenic effects in rats. Compared to another drug in the same class, Acetazolamide, Methazolamide requires a lower dose when administered to patients. References
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