Alcohol intolerance  is due to a genetic polymorphism of the enzyme alcohol dehydrogenase, the enzyme that metabolises ingested alcohol. This polymorphism is most often reported in Asian patients. It can also be an effect or side effect associated with certain drugs such as disulfiram, metronidazole, or nilutamide. Stuffy nose and skin flushing are the most common symptoms when ingesting alcohol. It may also be characterized as intolerance causing hangover symptoms similar to the "disulfiram-like reaction" of aldehyde dehydrogenase deficiency or chronic fatigue syndrome. Severe pain after drinking alcohol may indicate a more serious condition.If people are intolerant, some non-alcoholic beverages may be a problem, similar to alcohol-containing medications, vinegar, inhalation of alcohol or the vapour of alcohol-containing cleaning agents.Drinking alcohol first or afterwards together with calcium cyanamide, an inorganic compound used as a fertilizer, can cause permanent or long lasting intolerance (nitrolime disease), contributing  together with other substances to the accumulation of harmful acetaldehyde by inhibiting the enzyme acetaldehyde dehydrogenase. See also
Disulfiram-like drug
Alcohol flush reaction


== References ==
Labour or labor may refer to:

Childbirth, the delivery of a baby
Labour (human activity), or work
Manual labour, physical work
Wage labour, a socioeconomic relationship between a worker and an employer
Organized labour and the labour movement, consisting principally of labour unions
The Labour Party (UK)

Literature
Labor (journal), an American quarterly on the history of the labor movement
Labour/Le Travail, an academic journal focusing on the Canadian labour movement
Labor (Tolstoy book) or The Triumph of the Farmer or Industry and Parasitism (1888)

Places
La Labor, Honduras
Labor, Koper, Slovenia

Other uses
Labor (album), a 2013 album by MEN
Labor (area), a Spanish customary unit
"Labor", an episode of TV series Superstore
Labour (constituency), a functional constituency in Hong Kong elections
Labors, fictional robots in Patlabor

People with the surname
Earle Labor (born 1928), professor of American literature
Jérémy Labor (born 1992), French footballer
Josef Labor (1842–1924), Austrian musician and composer

See also
Labor Day (disambiguation)
Labour law
Labour Party (disambiguation)
Work (disambiguation)
All pages with titles beginning with Labour
All pages with titles containing Labour
All pages with titles beginning with Labor
All pages with titles containing Labor