Ensure adequate tissue perfusion (maintain SvO2 >70 with use of blood or dobutamine)
Address the underlying problem (i.e., antibiotic for infection, stent or CABG (coronary artery bypass graft surgery) for infarction, steroids for adrenal insufficiency, etc...)The best way to determine if a person will benefit from fluids is by doing a passive leg raise followed by measuring the output from the heart. Medication
Chronic hypotension sometimes requires the use of medications. Some medications that are commonly used include Fludrocortisone, Erythropoietin, and Sympathomimetics such as Midodrine and Noradrenaline and precursor (L-DOPS). Fludrocortisone is the first-line therapy (in the absence of heart failure) for patients with chronic hypotension or resistant orthostatic hypotension. It works by increasing the intravascular volume. Midodrine is a therapy used for severe orthostatic hypotension, and works by increasing peripheral vascular resistance. Noradrenaline and its precursor L-DOPS are used for primary autonomic dysfunction by increasing vascular tone. Erythropoietin is given to patients with neurogenic orthostatic hypotension and it works through increasing vascular volume and viscosity. Pediatrics
The definition of hypotension changes in the pediatric population depending on the childs age as seen in the table below. The clinical history provided by the caretaker is the most important part in determining the cause of hypotension in pediatric patients. Symptoms for children with hypotension include increased sleepiness, not using the restroom as much (or at all), having difficulty breathing or breathing rapidly, or syncope. The treatment for hypotension in pediatric patients is similar to the treatment in adults by following the four first steps listed above (see Treatment).
They are so expensive that gene therapy for haemophilia might be less expensive, especially for people with severe hemophilia. See also
Damoctocog alfa pegol, a recombinant antihemophilic factor VIII
Efmoroctocog alfa, a recombinant antihemophilic factor VIII
Moroctocog alfa, a recombinant antihemophilic factor VIII
Susoctocog alfa, a recombinant antihemophilic factor VIII
Turoctocog alfa, a recombinant antihemophilic factor VIII

References
External links
"Blood-coagulation factor VIII, procoagulant". Drug Information Portal. U.S. National Library of Medicine. "Beroctocog alfa". Drug Information Portal. U.S. National Library of Medicine. "Antihemophilic Factor (Recombinant) Monograph for Professionals". Drugs.com. "Antihemophilic Factor (Recombinant), Porcine Sequence Monograph for Professionals". Drugs.com. "Antihemophilic Factor (recombinant), Fc Fusion Protein Monograph for Professionals". Drugs.com. "Antihemophilic Factor (recombinant), Glycopegylated-exei Monograph for Professionals". Drugs.com.