Dandruff is a skin condition that mainly affects the scalp. Symptoms include flaking and sometimes mild itchiness. It can result in social or self-esteem problems. A more severe form of the condition, which includes inflammation of the skin, is known as seborrhoeic dermatitis.The cause is unclear, but believed to involve a number of genetic and environmental factors; the condition may worsen in the winter. It is not due to poor hygiene, and the underlying mechanism involves the excessive growth of skin cells. Diagnosis is based on symptoms.There is no known cure for dandruff. Antifungal cream, such as ketoconazole, or salicylic acid may be used to try to improve the condition. Dandruff affects about half of adults, with males more often affected than females. In addition, people in all areas of the world are affected. Onset is usually at puberty, and it becomes less common after the age of 50. Signs and symptoms
The main symptoms of dandruff are an itchy scalp and flakiness. Red and greasy patches of skin and a tingly feeling on the skin are also symptoms. Causes
The cause is unclear but believed to involve a number of genetic and environmental factors. As the skin layers continually replace themselves, cells are pushed outward where they die and flake off. For most individuals, these flakes of skin are too small to be visible. However, certain conditions cause cell turnover to be unusually rapid, especially in the scalp.
It is hypothesized that for people with dandruff, skin cells may mature and be shed in 2–7 days, as opposed to around a month in people without dandruff. The result is that dead skin cells are shed in large, oily clumps, which appear as white or grayish flakes on the scalp, skin and clothes. According to one study, dandruff has been shown to be possibly the result of three factors:
Skin oil, commonly referred to as sebum or sebaceous secretions
The metabolic by-products of skin micro-organisms (most specifically Malassezia yeasts)
Individual susceptibility and allergy sensitivity. Microorganisms
Older literature cites the fungus Malassezia furfur (previously known as Pityrosporum ovale) as the cause of dandruff. While this species does occur naturally on the skin surface of people both with and without dandruff, in 2007, it was discovered that the responsible agent is a scalp specific fungus, Malassezia globosa, that metabolizes triglycerides present in sebum by the expression of lipase, resulting in a lipid byproduct: oleic acid. During dandruff, the levels of Malassezia increase by 1.5 to 2 times its normal level. Oleic acid penetrates the top layer of the epidermis, the stratum corneum, and evokes an inflammatory response in susceptible people which disturbs homeostasis and results in erratic cleavage of stratum corneum cells. Seborrhoeic dermatitis
In seborrhoeic dermatitis, redness and itching frequently occur around the folds of the nose and eyebrow areas, not just the scalp. Dry, thick, well-defined lesions consisting of large, silvery scales may be traced to the less common condition of scalp psoriasis.