Although clinical trials only revealed an increased risk of insomnia, post-marketing surveillance showed that the drugs are associated with a possible increase in suicidal behavior and other side effects such as agitation, aggression, anxiousness, dream abnormalities and hallucinations, depression, irritability, restlessness, and tremor.In September 2019, the Pediatric Advisory Committee and the Drug Safety and Risk Management Advisory Committee met to discuss a pediatric-focused safety review of neuropsychiatric events with montelukast.In March 2020, the FDA required a boxed warning for montelukast to strengthen an existing warning about the risk of neuropsychiatric events associated with the drug in the wake of an increase in case reporting of neuropsychiatric events around the time of the initial communications about the concern from FDA in 2008. The boxed warning advises health care providers to avoid prescribing montelukast for people with mild symptoms, particularly those with allergic rhinitis because there are many other effective, less-concerned allergy medicines that are also indicated for the mild cases.In the FDAs self-conducted data analysis in comparison to their received case reports which were dependent on peoples self-claims, the propensity of developing neuropsychiatric disorders after montelukast use does not outpace that of inhaled corticosteroids; and there were no statistically significant risks of new-onset neuropsychiatric disorders among males, females, patients 12 years and older, patients with a psychiatric history, or after the 2008 FDA communication and prescribing information changes that first publicized the concern.
Both fetal malpresentation and cervical dystocia may result in obstructed labor. The cause of prolonged labor will determine the medical intervention that needs to take place. Medical professionals can either engage in preventive measures or turn to surgical methods of removing the fetus. If not handled properly or immediately treated, both the woman and the fetus can suffer a variety of long term complications, the most serious of which is death. There is no "quick fix" to prolonged labor, but there are preventive measures that can be taken, such as oxytocin infusions. In order to properly and safely deliver the baby, doctors will often intervene in child birth and conduct assisted vaginal delivery through the use of forceps or a vacuum extractor, or perform a Caesarean section. Signs and symptoms
Symptoms include:
Labor extends beyond 18 hours
Dehydration and exhaustion of the mother
Pain around the back, sides, and thighs of the mother as a result of extreme muscle pressure
Severe pain when labor begins
Increased heart rate of the mother
Swollen large intestine on either side of the uterus as a result of gas build up
Uterus sensitivity
Ketosis
Distress of the fetus
Uterine ruptures

Complications
Distress to the fetus as a result of decreasing oxygen levels
Internal bleeding of the fetuss head (intracranial hemorrhage)
Higher chance of operative delivery
Risks of long-term injuries to the infant such as hypoxic-ischemic encephalopathy (HIE) or cerebral palsy
Infection of the uterus
Damage to the birth canal
Postpartum infection
Postpartum hemorrhage

Prolonged latent labor
The term describes labor that occurs very slowly.