Other
Other uses include for dopamine-responsive dystonia (DRD) and restless legs syndrome.There is tentative evidence that it is useful in amblyopia when used with other treatments. Side effects
Common side effects include dizziness, drowsiness, blurred vision, vomiting, nausea, dry mouth, low appetite, heartburn, diarrhea, constipation, frequent sneezing, stuffiness of the nose, any of the symptoms of ordinary common cold, cough, muscle pain, hallucinations, numbness or a tingling sensation, disturbances of sleep, skin rash, itching, and/or headache.Less common, but more serious, side effects can include very frequent blinking or twitching of the eyes, fainting, mood changes such as confusion, depression, hallucinations, thoughts of suicide, or unusual strong urges (such as increased gambling), increases in the sex-drive, delusions (strongly-felt belief in something which is obviously not true), worsening of involuntary movements or spasms, and/or other movement problems. Patients should report these to their doctors as soon as possible. Mechanism of action
Levodopa is converted to dopamine via the action of a naturally occurring enzyme called DOPA decarboxylase. This occurs both in the peripheral circulation and in the central nervous system after levodopa has crossed the blood brain barrier. Activation of central dopamine receptors improves the symptoms of Parkinsons disease; however, activation of peripheral dopamine receptors causes nausea and vomiting.
It is important to train the calves relatively close to failure, which is 0-4 repetitions away from technical failure. They recover quickly, often requiring rest times of as little as 10 seconds and often no more than 60 seconds. Ensuring a 1-2 second pause at the top and bottom of the movement will put more emphasis on the muscle, and less emphasis on the achilles tendon. See also
Gastrocnemius muscle
Calf (disambiguation)
Calf raises
Shin
Sciatica


== References ==