It has a sensitivity of 80% and specificity of 73% in detecting pancreatic adenocarcinoma, and is used for following known cases rather than diagnosis. Histopathology
The most common form of pancreatic cancer (adenocarcinoma) is typically characterized by moderately to poorly differentiated glandular structures on microscopic examination. There is typically considerable desmoplasia or formation of a dense fibrous stroma or structural tissue consisting of a range of cell types (including myofibroblasts, macrophages, lymphocytes and mast cells) and deposited material (such as type I collagen and hyaluronic acid). This creates a tumor microenvironment that is short of blood vessels (hypovascular) and so of oxygen (tumor hypoxia). It is thought that this prevents many chemotherapy drugs from reaching the tumor, as one factor making the cancer especially hard to treat. Staging
Exocrine cancers
Pancreatic cancer is usually staged following a CT scan. The most widely used cancer staging system for pancreatic cancer is the one formulated by the American Joint Committee on Cancer (AJCC) together with the Union for International Cancer Control (UICC). The AJCC-UICC staging system designates four main overall stages, ranging from early to advanced disease, based on TNM classification of Tumor size, spread to lymph Nodes, and Metastasis.To help decide treatment, the tumors are also divided into three broader categories based on whether surgical removal seems possible: in this way, tumors are judged to be "resectable", "borderline resectable", or "unresectable".
Criminology
Non-consensual voyeurism is considered to be a form of sexual abuse. When the interest in a particular subject is obsessive, the behaviour may be described as stalking. The United States FBI assert that some individuals who engage in "nuisance" offences (such as voyeurism) may also have a propensity for violence based on behaviours of serious sex offenders. An FBI researcher has suggested that voyeurs are likely to demonstrate some characteristics that are common, but not universal, among serious sexual offenders who invest considerable time and effort in the capturing of a victim (or image of a victim); careful, methodical planning devoted to the selection and preparation of equipment; and often meticulous attention to detail.Little to no research has been done into the demographics of voyeurs. Legal status
Voyeurism is not a crime at common law. In common law countries it is only a crime if made so by legislation. In Canada, for example, voyeurism was not a crime when the case Frey v. Fedoruk et al. arose in 1947. In that case, in 1950, the Supreme Court of Canada held that courts could not criminalise voyeurism by classifying it as a breach of the peace and that Parliament would have to specifically outlaw it. On November 1, 2005, this was done when section 162 was added to the Canadian Criminal Code, declaring voyeurism to be a sexual offence when it violates a reasonable expectation of privacy.