Livedo reticularis is a common skin finding consisting of a mottled reticulated vascular pattern that appears as a lace-like purplish discoloration of the skin. The discoloration is caused by reduction in blood flow through the arterioles that supply the cutaneous capillaries, resulting in deoxygenated blood showing as blue discoloration. This can be a secondary effect of a condition that increases a persons risk of forming blood clots, including a wide array of pathological and nonpathological conditions. Examples include hyperlipidemia, microvascular hematological or anemia states, nutritional deficiencies, hyper- and autoimmune diseases, and drugs/toxins. The condition may be normal or related to more severe underlying pathology. Its differential diagnosis is broadly divided into possible blood diseases, autoimmune (rheumatologic) diseases, cardiovascular diseases, cancers, and endocrine disorders. It can usually (in 80% of cases) be diagnosed by biopsy.It may be aggravated by exposure to cold, and occurs most often in the lower extremities.The conditions name derives from the Latin livere which means bluish, and reticular which refers to the net-like pattern. Causes
A number of conditions may cause the appearance of livedo reticularis:

Cutis marmorata telangiectatica congenita, a rare congenital condition
Sneddon syndrome – association of livedoid vasculitis and systemic vascular disorders, such as  strokes, due to underlying genetic cause
Idiopathic livedo reticularis – the most common form of livedo reticularis, completely benign condition of unknown cause affecting mostly young women during the winter: It is a lacy purple appearance of skin in extremities due to sluggish venous blood flow. It may be mild, but ulceration may occur later in the summer.
Diuretics: Patients treated with fenoprofen may be resistant to the effects of loop diuretics and thiazides. Hydantoins, sulfonamides, sulfonylureas: Fenoprofen may displace these drugs from their binding site. Lithium: Renal Cl of lithium may be reduced and plasma levels may be elevated, which may increase the risk of lithium toxicity. Methotrexate: May increase methotrexate levels. Phenobarbital: May decrease fenoprofen t 1⁄2 . Dosage adjustments of fenoprofen may be required if phenobarbital is added or withdrawn. SSRIs (e.g. fluoxetine, citalopram): The risk of GI effects may be increased. Laboratory test interactions
False elevation in free and total serum T 3 as measured by Amerlex-M kit. Brand names
UK - Fenopron (Typharm Limited)
See also
Ibuprofen
Ketoprofen
Thalidomide
Chirality
Chiral drugs
Chiral inversion

References
External links
Fenoprofen info from Drugs.com