Alcohol especially has a large effect on young and developing brains and chances of further abuse, the culture surrounding the acceptable age of drinking therefore can be a biosocial factor. This however isnt always preventable, alcohol when consumed during pregnancy is profoundly damaging. The umbilical cord allows the mothers blood alcohol to reach the infant. Consumption of alcohol during pregnancy can result in miscarriage, and a number of physical and cognitive that can last a lifetime to the child. Therefore the biological implications of alcohol abuse are also further reaching than just the physical issues experienced by the consumer. Diagnosis
DSM-IV
Alcohol abuse was defined in the DSM-IV as a maladaptive pattern of drinking. For its diagnosis, at least one of the following criteria had to be fulfilled in the last 12 months:

Recurrent use of alcohol resulting in a failure to fulfill major role obligations at work, school, or home
Recurrent alcohol use in situations in which it is physically hazardous
Recurrent alcohol-related legal problems
Continued alcohol use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of alcohol

DSM-5
The alcohol abuse diagnosis is no longer used in the DSM-5 (released in 2013), it is now part of the alcohol use disorder diagnosis. Of the four alcohol abuse criteria, all except the one referring to alcohol-related legal problems are included in the alcohol use disorder criteria. Screening
The Alcohol Use Disorders Identification Test (AUDIT) is considered the most accurate alcohol screening tool for identifying potential alcohol misuse, including dependence.
Prognosis
The overall 5-year survival rate for follicular thyroid cancer is 91%, and the 10-year survival rate is 85%.By overall cancer staging into stages I to IV, follicular thyroid cancer has a 5-year survival rate of 100% for stages I and II, 71% for stage III, and 50% for stage IV.Compared to other variants of Follicular cell derived thyroid cancer, bone metastases are commonly associated with follicular carcinoma. In the present study a high rate of bone metastases of 34% was observed. References
External links

Thyroid cancer at DMOZ Archived 2017-03-14 at the Wayback Machine
Cancer Management Handbook: Thyroid and Parathyroid Cancers
Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer The American Thyroid Association Guidelines Taskforce (2015).