The lips appear dry, atrophic and fissured. Angular cheilitis is sometimes also present. Other causes
Lupus erythematosus, sometimes termed "lupus cheilitis"
Crohns disease (angular cheilitis)
"Nutritional cheilitis", e.g. pyridoxine (vitamin B6) deficiency
Lichen planus
Pemphigoid
Xerostomia

References
External links

 Media related to Cheilitis at Wikimedia Commons
Hypoplasminogenemia, also known as plasminogen deficiency type 1, is a genetic disorder characterized by a lack of the protein plasminogen, which is responsible for the ability of the body to break down fibrin clots. Plasminogen deficiency leads to an accumulation of fibrin, causing the development of growths (lesions) that can impair normal tissue and organ function and may lead to blindness when these lesions affect the eyes.It is caused by mutations in the PLG gene. Treatment
Plasminogen, human-tvmh (Ryplazim) was approved for medical use in the United States in June 2021. It is the first therapy for hypoplasminogenemia approved by the U.S. Food and Drug Administration (FDA). References
External links
Congenital plasminogen deficiency MeSH, National Library of Medicine