One-third to one-half of infants are stillborn, with all but a few dying in the neonatal period.In cases of monoamniotic twins where one is affected, the twin with sirenomelia is protected from Potter sequence (particularly pulmonary hypoplasia and abnormal facies) by the normal twins production of amniotic fluid. Epidemiology
This condition is found in approximately one out of every 100,000 live births; studies produce rates from 1 in 68,741 to 1 in 97,807. It is 100 to 150 times more likely in identical (monozygotic) twins than in singletons or fraternal twins. Sirenomelia is not associated with any ethnic background, but fetuses with sirenomelia are more likely to be male. Etymology
The word sirenomelia derives from the ancient Greek word seirēn, referring to the mythological Sirens, who were sometimes depicted as mermaids, and melos, meaning "limb". History
Sirenomelia was first reported in 1542. In 1927, Otto Kampmeier discovered the association between sirenomelia and single umbilical artery. Notable individuals
Only a few individuals who had some functioning kidney tissue have survived the neonatal period. Tiffany Yorks
Tiffany Yorks of Clearwater, Florida (May 7, 1988 – February 24, 2016) underwent successful surgery in order to separate her legs before she was a year old. She was the longest-surviving sirenomelia patient to date. She had mobility issues due to her fragile leg bones, and compensated by using crutches or a wheelchair. She died on February 24, 2016, at the age of 27.
Oophoritis is an inflammation of the ovaries. It is often seen in combination with salpingitis (inflammation of the fallopian tubes). It may develop in response to infection. See also
Pelvic inflammatory disease

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