Prognosis
VAP occurring early after intubation typically involves fewer resistant organisms and is thus associated with a more favorable outcome. Because respiratory failure requiring mechanical ventilation is itself associated with a high mortality, determination of the exact contribution of VAP to mortality has been difficult. As of 2006, estimates range from 33% to 50% death in patients who develop VAP. Mortality is more likely when VAP is associated with certain microorganisms (Pseudomonas, Acinetobacter), blood stream infections, and ineffective initial antibiotics. VAP is especially common in people who have acute respiratory distress syndrome (ARDS). Epidemiology
Between 8 and 28% of patients receiving mechanical ventilation are affected by VAP. VAP can develop at any time during ventilation, but occurs most often in the first week of mechanical ventilation. There is some evidence for gender differences in the course of VAP: men have been found to get VAP more often, but women are more likely to die after contracting VAP. Recent reports indicate that patients with Coronavirus disease 2019 who require mechanical ventilation in an Intensive care unit are at increased risk of ventilator-associated pneumonia, compared to patients without COVID-19 ventilated in the same unit and patients who had viral pneumonitis arising from viruses other than SARS-CoV-2. Why this increased susceptibility should be present remains uncertain, as the noted reports adjusted for duration of ventilation, it is likely that the increased susceptibility relates impaired innate immunity in the lungs.
Others liken the pain and sensation to a chemical burn that doesnt go away. It is a mistake to think that the reaction is like a sunburn, it is far deeper in the skin and often requires the use of ingestible steroids as well as topical steroids in order to alleviate the condition to a degree. The best protection is to be fully covered from sunlight, even when cloudy or hazy. The use of UV-rated clothing is suggested as well as a UV-rated umbrella for outdoors. See also
List of cutaneous conditions
Photosensitivity with HIV infection
Skin lesion

References


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