In 1986 Dyazide was the most prescribed drug in the US and had $325 million in sales, making it SmithKline Beckmans second-biggest seller behind Tagamet.The patents had expired on Dyazide in 1980, but complications arose with the introductions of generics, because the formulation of Dyazide resulted in variable batches that made it impossible for generic manufacturers to show that their versions were bioequivalent.Bolar Pharmaceutical was in the running to be the first to bring a generic, but its application was delayed by these concerns about whether its formulation provided the same amount of each drug; these were complicated by accusations that Bolar had fraudulently substituted Dyazide for its own version to conduct studies that were submitted to the FDA. Shortly after Bolars generic was approved, further concerns were raised with regard to Bolars applications to market generics more generally; these findings among others raised widespread concern among doctors and the public over whether generics were really the same as branded drugs. Bolar ended up recalling its generic form of Dyazide and withdrawing the product in 1990. In 1991 the US Justice Department on behalf of the FDA filed 20 criminal charges against Bolar for its fraud, and early the next year Bolar pled guilty and agreed to pay a $10M fine.
Amok may refer to:

Running amok, the act of behaving disruptively or uncontrollably. Film
Amok (1934 film), a French film
Amok (1944 film), a Mexican romantic drama
Amok (1983 film), a Moroccan drama

Literature
Amok (comics), an Italian comic book series
Amok (novella), by Stefan Zweig, 1922
Amok, a 1974 novel by Harry Thürk
Amok, a 2003 novel by Krystian Bala

Music
Amok (The Late B.P. Helium album), 2004
Amok (Sentenced album), 1995
Amok (Atoms for Peace album), 2013

Other uses
Steamed curry (Khmer: អាម៉ុក, amŏk), name in Cambodia for a curry steam-cooked in banana leaves
Fish amok, a Cambodian steamed fish curry
Amok (video game), a 1996 video game for the Sega Saturn
Mok language, also known as Amok
Amok (publisher), now Frémok, a Franco-Belgian comics publishing house
Amok Press, a defunct American book imprint

See also
All pages with titles beginning with Amok
All pages with titles containing Amok
"Amok Time", a 1967 episode of Star Trek: The Original Series
Amuck!, a 1972 Italian giallo film
AMOC (disambiguation)