Mild-to-moderate IPF has been characterized by the following functional criteria:
Forced vital capacity (FVC) of ≥50%
DLCO of ≥30%
6MWT distance ≥150 meters. Treatment
The goals of treatment in IPF are essentially to reduce the symptoms, stop disease progression, prevent acute exacerbations, and prolong survival. Preventive care (e.g. vaccinations) and symptom-based treatment should be started early in every patient. Oxygen therapy
In the 2011 IPF guidelines, oxygen therapy, or supplementary oxygen for home use, became a strong recommendation for use in those patients with significantly low oxygen levels at rest. Although oxygen therapy has not been shown to improve survival in IPF, some data indicate an improvement in exercise capacity. Pulmonary rehabilitation
Fatigue and loss of muscular mass are common and disabling problems for patients with IPF. Pulmonary rehabilitation may alleviate the overt symptoms of IPF and improve functional status by stabilizing and/or reversing the extrapulmonary features of the disease. The number of published studies on the role of pulmonary rehabilitation in idiopathic pulmonary fibrosis is small, but most of these studies have found significant short-term improvements in functional exercise tolerance, quality of life, and dyspnea on exertion. Typical programs of rehabilitation include exercise training, nutritional modulation, occupational therapy, education and psychosocial counseling. In the late phase of disease, IPF patients tend to discontinue physical activity due to increasing dyspnea. Whenever possible, this should be discouraged. Medications
A number of treatments have been investigated in the past for IPF, including interferon gamma-1β, bosentan, ambrisentan, and anticoagulants, but these are no longer considered effective treatment options.
Taeniasis is an infection within the intestines by adult tapeworms belonging to the genus Taenia. There are generally no or only mild symptoms. Symptoms may occasionally include weight loss or abdominal pain. Segments of tapeworm may be seen in the stool. Complications of pork tapeworm may include cysticercosis.Types of Taenia that cause infections in humans include Taenia solium (pork tapeworm), Taenia saginata (beef tapeworm), and Taenia asiatica (Asian tapeworm). Taenia saginata is due to eating contaminated undercooked beef while Taenia solium and Taenia asiatica is from contaminated undercooked pork. Diagnosis is by examination of stool samples.Prevention is by properly cooking meat. Treatment is generally with praziquantel, though niclosamide may also be used. Together with cysticercosis, infections affect about 50 million people globally. The disease is most common in the developing world. In the United States less than 1,000 cases occur a year. Signs and symptoms
Taeniasis generally has few or no symptoms. It takes about 8 weeks from infection for adult worms to form and can last for years without treatment.Infection may be suspected when a portion of the worm is passed in the stool. It is not generally fatal. Pork tapeworm
Infection in the intestines by the adult T. solium worms is normally asymptomatic. Heavy infection can result in anaemia and indigestion.A complication, known as cysticercosis, may occur if the eggs of the pork tapeworm are eaten. This typically occurs from vegetables or water contaminated by feces from someone with pork tapeworm taeniasis.