False negatives are often common with serum precipitins because of lack of testing reagents for many antigens.Precipitating IgG antibodies against fungal or avian antigens can be detected in the laboratory using the traditional Ouchterlony immunodiffusion method wherein precipitin lines form on agar plate. The ImmunoCAP technology has replaced this time-consuming, labor-intensive method with their automated CAP assays and FEIA (Fluorescence enzyme immunoassay) that can detect IgG antibodies against Aspergillus fumigatus (Farmers lung or for ABPA) or avian antigens (Bird Fanciers Lung). Differential Diagnosis
Organic dust toxic syndrome presents similarly with fevers, chills a few hours after exposure to bioaerosols with toxins from fungi, however this is not a true hypersensitivity reaction because it occurs on initial exposure without a preceding sensitization In chronic disease, HP must be differentiated from very similarly presenting idiopathic pulmonary fibrosis.Although overlapping in many cases, hypersensitivity pneumonitis may be distinguished from occupational asthma in that it is not restricted to only occupational exposure, and that asthma generally is classified as a type I hypersensitivity. Unlike asthma, hypersensitivity pneumonitis targets lung alveoli rather than bronchi.Similarly, sarcoidosis has noncaseating granuloma formation, however hilar adenopathy is often seen on chest radiographs. Treatment
The best treatment is to avoid the provoking allergen, as chronic exposure can cause permanent damage and acute disease is often self-limiting. The identification of the provoking antigen and its location must be ascertained by conducting an exposure assessment. Home cleaning is one method of antigen avoidance.
Deaf-mute is a term which was used historically to identify a person who was either deaf and used sign language or both deaf and could not speak. The term continues to be used to refer to deaf people who cannot speak an oral language or have some degree of speaking ability, but choose not to speak because of the negative or unwanted attention atypical voices sometimes attract. Such people communicate using sign language. Some consider it to be a derogatory term if used outside its historical context; the preferred term today is simply "deaf". Historical usage of "deaf-mute" and other terms
United Kingdom
In 19th century British English "mute" and "dumb" meant "non-speaking", and were not pejorative terms. For example, in 1889 Queen Victoria instigated the Royal Commission on The Blind, the Deaf and Dumb etc.in the United Kingdom. The intention was to examine contemporary education and employment of blind or deaf people, with a view to improving conditions for them. The Oxford English Dictionary states that the North American pejorative usage of the word to imply stupidity was first noted in the UK in 1928. According to the OED, "deaf-mute" was coined in the early 19th century as a medical term for an inability to speak as a consequence of deafness. There is no mention of offensiveness of this term in the UK. North America
The primary definition of "dumb" in Websters Dictionary is "lacking intelligence" or "stupid". Its second definition of the word is "lacking the ability to speak ... now often offensive".