The Stoics held with four basic categories, all viewed as bodies (substantial and insubstantial): (1) substance in the sense of substrate, primary formless matter; (2) quality, matters organization to differentiate and individualize something, and coming down to a physical ingredient such as pneuma, breath; (3) somehow holding (or disposed), as in a posture, state, shape, size, action, and (4) somehow holding (or disposed) toward something, as in relative location, familial relation, and so forth. Immanuel Kant expounded a table of judgments involving four three-way alternatives, in regard to (1) Quantity, (2) Quality, (3) Relation, (4) Modality, and, based thereupon, a table of four categories, named by the terms just listed, and each with three subcategories. Arthur Schopenhauers doctoral thesis was On the Fourfold Root of the Principle of Sufficient Reason. Franz Brentano held that any major philosophical period has four phases: (1) Creative and rapidly progressing with scientific interest and results; then declining through the remaining phases, (2) practical, (3) increasingly skeptical, and (4) literary, mystical, and scientifically worthless—until philosophy is renewed through a new periods first phase. (See Brentanos essay "The Four Phases of Philosophy and Its Current State" 1895, tr. by Mezei and Smith 1998.)
"Fountains syndrome: mental retardation, sensorineural deafness, skeletal abnormalities, and coarse face with full lips". J Med Genet. 26 (11): 722–724. doi:10.1136/jmg.26.11.722. PMC 1015742. PMID 2585470. Fryns JP, Dereymaeker A, Hoefnagels M, Van den Berghe H (1987). "Mental retardation, deafness, skeletal abnormalities, and coarse face with full lips: confirmation of the Fountain syndrome". Am J Med Genet. 26 (3): 551–555. doi:10.1002/ajmg.1320260307. PMID 3565469. Dunkle Mary (1996). "Fountain Syndrome". NORD. Retrieved 26 April 2012. "Fountain syndrome". Ailments.com. 2000. Retrieved 29 April 2012. "Childrens Health:Fountain syndrome". WebMD. 2011. Retrieved 30 April 2012. External links

Online Mendelian Inheritance in Man (OMIM): 229120