Side effects
The most common side effects are dizziness (11.5%) and constipation (10.9%). Other side effects include headache and nausea. Drug interactions
Ranolazine is metabolized mainly by the CYP3A enzyme. It also inhibits another metabolizing enzyme, cytochrome CYP2D6. For this reason, the doses of ranolazine and drugs that interact with those enzymes need to be adjusted when they are used by the same patient. Ranolazine should not be used with drugs such as ketoconazole, clarithromycin, and nelfinavir that strongly inhibit CYP3A, nor with drugs that activate CYP3A, such as rifampin and phenobarbital.For drugs that are moderate CYP3A inhibitors, such as diltiazem, verapamil, and erythromycin, the dose of ranolazine should be reduced.Drugs that are metabolized by CYP2D6, such as tricyclic antidepressants, may need to be given at reduced doses when administered with ranolazine. Mechanism of action
Ranolazine inhibits persistent or late inward sodium current (INa) in heart muscle in a variety of voltage-gated sodium channels. Inhibiting that current leads to reductions in intracellular calcium levels. This in turn leads to reduced tension in the heart wall, leading to reduced oxygen requirements for the muscle. The QT prolongation effect of ranolazine on the surface electrocardiogram is the result of inhibition of IKr, which prolongs the ventricular action potential.
Yasmin, Yasmine or Yasmina may refer to:

Yasmin (given name), a common female nameYasmin - Jasmine Flower

Yasmin (musician), a female British DJ and singer-songwriter
Yasmine (singer), a female Belgian singer, presenter and television personality. Yasmin (drug), marketing name of a birth control pill
Yasmin, a doll in the Bratz fashion doll line

Film and television
Yasmin (1955 film), a 1955 Hindi film directed by Abdur Rashid Kardar and starring Vyjayanthimala
Yasmin (2004 film), a 2004 English film directed by Kenneth Glenaan and starring Archie Panjabi
Yasmine (film), a 2014 Bruneian film
Yasmins Getting Married, an Australian reality television show
Yasmina (film), a 1927 French silent film

See also
Jasmin (disambiguation)
Jasmine (disambiguation)
Yasemin (disambiguation)