Fever has been described in teaching texts as assisting the healing process in various ways, including:

increased mobility of leukocytes;: 1044 
enhanced leukocyte phagocytosis;: 1030 
decreased endotoxin effects;: 1029  and
increased proliferation of T cells. : 1030 : 212

Advantages and disadvantages
Having a fever response in response to an infectious disease is generally regarded as protective, whereas fever in non-infections may be maladaptive. Studies have not been consistent on whether treating fever generally worsens or improves mortality risk. Benefits or harms may depend on the type of infection, health status of the patient and other factors. Studies using warm-blooded vertebrates suggest that they recover more rapidly from infections or critical illness due to fever. In sepsis, fever is associated with reduced mortality. Pathophysiology of fever induction
Hypothalamus
Temperature is regulated in the hypothalamus. The trigger of a fever, called a pyrogen, results in the release of prostaglandin E2 (PGE2). PGE2 in turn acts on the hypothalamus, which creates a systemic response in the body, causing heat-generating effects to match a new higher temperature set point. There are four receptors in which PGE2 can bind (EP1-4), with a previous study showing the EP3 subtype is what mediates the fever response. Hence, the hypothalamus can be seen as working like a thermostat. When the set point is raised, the body increases its temperature through both active generation of heat and retention of heat. Peripheral vasoconstriction both reduces heat loss through the skin and causes the person to feel cold.
POIS that is manifest from the first ejaculations in adolescence is called primary type; POIS that starts later in life is called secondary type.Many individuals with POIS report lifelong premature ejaculation, with intravaginal ejaculation latency time (IELT) of less than one minute. The 7 clusters of symptoms of criterion 1:

Synonyms and related conditions
POIS has been called by a number of other names, including "postejaculatory syndrome", "postorgasm illness syndrome", "post ejaculation sickness", and "post orgasmic sick syndrome".Dhat syndrome is a condition, first described in 1960 in India, with symptoms similar to POIS. Dhat syndrome is thought to be a culture-bound psychiatric condition and is treated with cognitive behavioral therapy along with anti-anxiety and antidepressant drugs.Post-coital tristesse (PCT) is a feeling of melancholy and anxiety after sexual intercourse that lasts anywhere from five minutes to two hours. PCT, which affects both men and women, occurs only after sexual intercourse and does not require an orgasm to occur, and in that its effects are primarily emotional rather than physiological. By contrast, POIS affects only men, consists primarily of physiological symptoms that are triggered by ejaculation and that can last, in some people, for up to a week. While PCT and POIS are distinct conditions, some doctors speculate that they could be related.An array of more subtle and lingering symptoms after orgasm, which do not constitute POIS, may contribute to habituation between mates.