References
This article contains text from the public domain document "Questions and Answers about Shoulder Problems" (PDF). National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health Public Health Service. U.S. Department of Health and Human Services. March 2006. NIH Publication No. 01-4865. Archived from the original (PDF) on 10 May 2007. External links
 
Rotator Cuff Tears. Wheeless Textbook of Orthopedics. A description of rotator cuff tears from Wheeless
Physiotherpy program for rortator cuff tears
Approximately 80% of males with myotubular myopathy diagnosed by muscle biopsy have mutations in MTM1, and about 7% of these mutations are genetic deletions.Centronuclear myopathies where the genetic abnormality is NOT sex-linked (e.g., not located on the X chromosome) are considered autosomal. Autosomal abnormalities can either be dominant or recessive, and are often referred to as AD for "autosomal dominant" or AR for "autosomal recessive").Many researchers use the term "myotubular myopathy" (MTM) only for cases when the genetic test has come back positive for abnormalities (genetic mutations) at the MTM1 gene on the X chromosome. Cases with a centronuclear (nucleus in the center) appearance on muscle biopsy but a normal genetic test for MTM1 would be referred to as centronuclear myopathy until such time as a specific genetic site is identified to give a more detailed sub-classification.The possible combinations of inheritance of myotubular myopathy are as follows:

Sporadic cases have also been reported where there is no previous family history (these cases are presumably due to a new mutation that was not present in either parent). Pathology
On examination of muscle biopsy material, the nuclear material is located predominantly in the center of the muscle cells, and is described as having any "myotubular" or "centronuclear" appearance. In terms of describing the muscle biopsy itself, "myotubular" or "centronuclear" are almost synonymous, and both terms point to the similar cellular-appearance among MTM and CNM.