Also, topical treatment of eyes of dry eye mice (Aire knockout mouse model of dry eye) restored tearing, and suppressed both corneal staining and the size of inflammatory foci in lacrimal glands. Additional causes
Aging is one of the most common causes of dry eyes because tear production decreases with age. Several classes of medications (both prescription and OTC) have been hypothesized as a major cause of dry eye, especially in the elderly. Particularly, anticholinergic medications that also cause dry mouth are believed to promote dry eye. Dry eye may also be caused by thermal or chemical burns, or (in epidemic cases) by adenoviruses. A number of studies have found that diabetics are at increased risk for the disease.About half of all people who wear contact lenses complain of dry eyes. There are two potential connections between contact usage and dry eye. Traditionally, it was believed that soft contact lenses, which float on the tear film that covers the cornea, absorb the tears in the eyes. The connection between a loss in nerve sensitivity and tear production is also the subject of current research.Dry eye also occurs or becomes worse after LASIK and other refractive surgeries, in which the corneal nerves which stimulate tear secretion are cut during the creation of a corneal flap. Dry eye caused by these procedures usually resolves after several months, but it can be permanent.
Diagnostic criteria
Three or more of the following five criteria must be met:

Age 50 years or more
New developed headache
Tenderness of the superficial temporal artery
Elevated sedimentation rate, at least 50 mm/hour (blood test that reveals inflammatory activity)
Giant cell arteritis in a biopsy specimen from the temporal artery

Takayasus arteritis
Symptoms
Starts with nonspecific symptoms such as:

Localized joint pain
Fever
Fatigue
Headaches
Rashes
Weight loss
Diagnosis usually does not happen until the blockage causes deficient blood flow to the extremities or to a stroke. Classification criteria
Three or more of the following six criteria must be met:

Age when disease starts is under 50
Decreased brachial artery pulse
Systolic blood pressure differs by more than 10mmHg between arms
Cramping caused by exercise in the extremities
Abnormal sounds (through stethoscope) over subclavian arteries or abdominal aorta
A narrowing or blockage in the aorta, its primary branches, or large arteries as seen through a radiograph of the arteries.