Furthermore, the combination of isatuximab and pomalidomide will lead to an extra enhanced antitumor activity in MM cells. Thus, pomalidomide in vivo and in vitro leads to an increase of the activity of isatuximab.Animal studies in reproduction toxicity have not yet been carried out. So, the risks of birth defects and miscarriage risks are unknown. Names
Isatuximab is the United States Adopted Name (USAN).It was developed by ImmunoGen and Sanofi-Aventis with the development name SAR-650984. See also
Daratumumab, another anti-CD38 antibody

References
External links
"Isatuximab". Drug Information Portal. U.S. National Library of Medicine. Clinical trial number NCT02990338 for "Multinational Clinical Study Comparing Isatuximab, Pomalidomide, and Dexamethasone to Pomalidomide and Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma Patients (ICARIA-MM)" at ClinicalTrials.gov
Coccidia in chickens
Coccidiosis is a significant disease for chickens, especially affecting the young chicks. It can be fatal or leave the bird with compromised digestion. There are chick feed mixes that contain a coccidiostat to manage exposure levels and control disease. In an outbreak, coccidiocidal medications are given. Examples are toltrazuril (Baycox) or amprolium. After multiple infections, surviving chickens become resistant to the coccidia. Coccidia in cattle
Coccidiosis (in cattle also known as Eimeriosis) is one of the most important diseases in calves and youngstock both under housing conditions and when grazing. Symptoms are generally caused by the species Eimeria zuernii and Eimeria bovis and include loss of appetite, fatigue, dehydration, and watery, sometimes bloody, diarrhoea. Outbreaks are known to occur in cattle herds. The parasite can infect all animals on the farm and in some countries the parasite is present on all farms. Coccidiosis affects the growth and sometimes survival of the calves and consequently affect the production and the profitability of cattle livestock production. Coccidia in goats
Coccidiosis is also present in goats, and is the largest cause of diarrhea in young goats. It can also cause high temperature and loss of appetite. Genera and species that cause coccidiosis
Genus Isospora is the most common cause of intestinal coccidiosis in dogs and cats. Species of Isospora are host-specific, infecting only one species. Species that infect dogs include I. canis, I. ohioensis, I. burrowsi, and I. neorivolta. Species that infect cats include I. felis and I. rivolta. The most common symptom is diarrhea.