Megalopapilla is a non-progressive human eye condition in which the optic nerve head (optic disc) has an enlarged diameter, exceeding 2.1 mm with no other morphological abnormalities. Clinical features
In megalopapilla the optic disc diameter exceeds 2.1 mm (or surface area more than 2.5 mm2) with an increased cup-to-disc ratio. Although the optic disc is looks abnormal, the disc colour, sharpness of disc margin, rim volume, configuration of blood vessels and intraocular pressure will be normal. Visual field is normal except for an enlarged blind spot. Visual acuity may be normal, or occasionally reduced. Types
There are two types of megalopapilla. Type 1, which is the most common, is bilateral with a normal configuration of the optic cup. Type 2 is unilateral with a superiorly displaced cup that eliminates the adjacent neuro-retinal rim. Diagnosis and differential diagnosis
Large disc size can be seen in fundus examination by ophthalmoscopy. Since OCT is not influenced by disc size, it can be used in differentiating normal and glaucomatous eyes with large discs.Since the clinical appearance of megalopapilla resembles that of glaucomatous optic disc, it should be differentiated from Normal tension glaucoma and other pseudo-glaucomatous diseases. Other conditions that resembles megalopapilla includes coloboma of optic disc and orbital optic disc glioma. History
Bock and Franceschetti were the first to use the term megalopapilla to describe larger-than-normal optic disks. == References ==
Stasis dermatitis refers to the skin changes that occur in the leg as a result of "stasis" or blood pooling from insufficient venous return; the alternative name of varicose eczema comes from a common cause of this being varicose veins.Insufficient venous return results in increased pressure in the capillaries with the result that both fluid and cells may "leak" out of the capillaries. This results in red cells breaking down, with iron containing hemosiderin possibly contributing to the pathology of this entity. Symptoms
Stasis dermatitis may be characterized by:

Skin that appears thin, brown and tissue-like, with possible skin lesions (macule or patches), red spots, superficial skin irritation and/or darkening and/or thickening of the skin at the ankles or legs
Weak skin may ulcerate in some areas and legs, ankles, or other areas may become swollen
Open sores, ulcers
Itching and/or leg pains
Sometimes pain may persist from swollen tissues and may feel like "stabbing" or "needle pricks"If skin continues to deteriorate and breaks down, a venous ulcer (also known as a stasis ulcer) may form. Without proper wound care, open cracks predispose patients for the entry of a bacterial infection, causing cellulitis in the leg. Diagnosis
Stasis dermatitis is diagnosed clinically by assessing the appearance of red plaques on the lower legs and the inner side of the ankle. Stasis dermatitis can resemble a number of other conditions, such as cellulitis and contact dermatitis, and at times needs the use of a duplex ultrasound to confirm the diagnosis or if clinical diagnosis alone is not sufficient.