Krukenberg tumors are most commonly metastases from gastric cancer, particularly adenocarcinoma, or breast cancer particularly invasive lobular breast carcinoma, but they can arise in the appendix, colon, small intestine, rectum, gallbladder, and urinary bladder or gallbladder, biliary tract, pancreas, ampulla of Vater or uterine cervix.Immunohistochemistry may help in diagnosing Krukenberg tumors from primary ovarian neoplasms but needs to be applied with discretion. For example, tumors that are immunoreactive to CEA or cytokeratin 20 (CK20) and negative for cytokeratin 7 (CK7) may be more likely to be of colorectal origin. Treatment and prognosis
Since Krukenberg tumors are secondary (metastatic), management might logically be driven by identifying and treating the primary cancer. The optimal treatment of Krukenberg tumors is unclear. The role of surgical resection has not been adequately addressed but if metastasis is limited to the ovaries, surgery may improve survival. The role of chemotherapy and/or radiotherapy is uncertain but may sometimes be beneficial. History
Krukenberg tumors are named after Friedrich Ernst Krukenberg (1871–1946),  who reported what he thought was a new type of primary ovarian malignancy in 1896;  six years later these were shown to be of metastatic gastrointestinal tract origin. However, Paget had described the process in 1854. References
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Junctional epidermolysis bullosa may refer to:

Junctional epidermolysis bullosa (medicine)
Junctional epidermolysis bullosa (veterinary medicine)