They each combine demographic and laboratory data to estimate severity or probability of death. Examples include APACHE II, Ranson, BISAP, and Glasgow. The Modified Glasgow criteria suggests that a case be considered severe if at least three of the following are true:
Age > 55 years
Blood levels:
PO2 oxygen < 60 mmHg or 7.9 kPa
White blood cells > 15,000/µlitre
Calcium < 2 mmol/litre
Blood urea nitrogen  > 16 mmol/litre
Lactate dehydrogenase (LDH) > 600iu/litre
Aspartate transaminase (AST) > 200iu/litre
Albumin < 32g/litre
Glucose > 10 mmol/litreThis can be remembered using the mnemonic PANCREAS:

PO2 oxygen < 60 mmHg or 7.9 kPa
Age > 55
Neutrophilia white blood cells > 15,000/µlitre
Calcium < 2 mmol/litre
Renal function (BUN) > 16 mmol/litre
Enzymes lactate dehydrogenase (LDH) > 600iu/litre aspartate transaminase (AST) > 200iu/litre
Albumin < 32g/litre
Sugar glucose > 10 mmol/litreThe BISAP score (blood urea nitrogen level >25 mg/dl (8.9 mmol/L), impaired mental status, systemic inflammatory response syndrome, age over 60 years, pleural effusion) has been validated as similar to other prognostic scoring systems. Epidemiology
Globally the incidence of acute pancreatitis is 5 to 35 cases per 100,000 people. The incidence of chronic pancreatitis is 4–8 per 100,000 with a prevalence of 26–42 cases per 100,000. In 2013 pancreatitis resulted in 123,000 deaths up from 83,000 deaths in 1990. Costs
In adults in the United Kingdom, the estimated average total direct and indirect costs of chronic pancreatitis is roughly £79,000 per person on an annual basis. Acute recurrent pancreatitis and chronic pancreatitis occur infrequently in children, but are associated with high healthcare costs due to substantial disease burden.
Traditionally, people were not allowed to eat until the inflammation resolved but more recent evidence suggests early feeding is safe and improves outcomes, and may result in an ability to leave the hospital sooner.Due to inflammation occurring in pancreatitis, proinflammatory cytokines secreted into the bloodstream can cause inflammation throughout the body, including the lungs and can manifest as ARDS. Because pancreatitis can cause lung injury and affect normal lung function, supplemental oxygen is occasionally delivered through breathing tubes that are connected via the nose (e.g., nasal cannulae) or via a mask. The tubes can then be removed after a few days once it is clear that the condition is improving. Dehydration may result during an episode of acute pancreatitis, so fluids will be provided intravenously. Opioids may be used for the pain. When the pancreatitis is due to gallstones, early gallbladder removal also appears to improve outcomes. Severe acute pancreatitis
Severe pancreatitis can cause organ failure, necrosis, infected necrosis, pseudocyst, and abscess. If diagnosed with severe acute pancreatitis, people will need to be admitted to a high-dependency unit or intensive care unit. It is likely that the levels of fluids inside the body will have dropped significantly as it diverts bodily fluids and nutrients in an attempt to repair the pancreas. The drop in fluid levels can lead to a reduction in the volume of blood within the body, which is known as hypovolemic shock. Hypovolemic shock can be life-threatening as it can very quickly starve the body of the oxygen-rich blood that it needs to survive.