When kept dry and away from further trauma, the nail will reattach from the base upward (i.e., from proximal to distal).The aim of treatement is also to eliminate onychomycosis that is a major cause of onycholysis .Anti-biotics like Terbinafin and itraconazole in the form of oral pills should be given for 6 to 8 weeks. If the underlying cause of the condition is not found and the nail continues to detach despite conservative treatment, the nail bed may begin to form a granular layer of abnormal cells on its surface. After six months of detachment, this layer is likely to prevent the adhesion of any new nail tissue, possibly leading to permanent deformity. Etymology
The word onycholysis comes from onycho-, from Ancient Greek ὄνυξ ónuks nail, and Ancient Greek λύσις lúsis lysis/disintegration. See also
List of cutaneous conditions
Plummers nail

References


== External links ==
Diagnosis
The hallmark features of this syndrome are poorly developed fingernails, toenails, and patellae (kneecaps). Sometimes, this disease causes the affected person to have either no thumbnails or a small piece of a thumbnail on the edge of the thumb. The lack of development or complete absence of fingernails results from the loss of function mutations in the LMX1B gene. This mutation may cause a reduction in dorsalising signals, which then results in the failure to normally develop dorsal specific structures such as nails and patellae. Other common abnormalities include elbow deformities, abnormally shaped pelvic (hip) bones, and kidney disease. Treatment
Treatment for NPS varies depending on the symptoms observed. Perform screening for kidney disease and glaucoma, surgery, intensive physiotherapy, or genetic counseling. ACE inhibitors are taken to treat proteinuria and hypertension in NPS patients. Dialysis and kidney transplant. Physical therapy, bracing and analgesics for joint pain. See also
List of cutaneous conditions
List of radiographic findings associated with cutaneous conditions

References
External links
GeneReview/NCBI/NIH/UW entry on nail–patella syndrome