Experimental therapies that are currently not approved for treatment as of March 2022 include the following:
A gene therapy treatment that is in early-phase clinical trials, with the technology licensed to AvroBio. Plant-based ERT (pegunigalsidase alfa) under development by the company Protalix
The substrate reduction therapy Venglustat (Ibiglustat) under development by Sanofi-Genzyme
Bio-better ERT (CDX-6311) under pre-clinical development by the company Codexis
A gene therapy (ST-920) under development by the company Sangamo. Organ-specific treatment
Pain associated with Fabry disease may be partially alleviated by enzyme replacement therapy in some patients, but pain management regimens may also include analgesics, anticonvulsants, and nonsteroidal anti-inflammatory drugs, though the latter are usually best avoided in kidney disease. The kidney failure seen in some of those with Fabry disease sometimes requires haemodialysis. The cardiac complications of Fabry disease include abnormal heart rhythms, which may require a pacemaker or implantable cardioverter-defibrillator, while the restrictive cardiomyopathy often seen may require diuretics. Prognosis
Life expectancy with Fabry disease for males was 58.2 years, compared with 74.7 years in the general population, and for females 75.4 years compared with 80.0 years in the general population, according to registry data from 2001 to 2008. The most common cause of death was cardiovascular disease, and most of those had received kidney replacements. Epidemiology
Fabry disease is panethnic, but due to its rarity, determining an accurate disease frequency is difficult. Reported incidences, ranging from one in 476,000 to one in 117,000 in the general population, may largely underestimate the true prevalence.
The Village (Korean drama): "Achiaras Secret" features daughters of a serial rapist who find each other because they share Fabry disease. Doctor John (Korean drama): In episode two, a prisoner is diagnosed with Fabry disease. In Lincoln Rhyme: Hunt for the Bone Collector, a copycat of the titular Bone Collector has Fabry disease and takes Galafold, which allows the detectives to learn his identity. Partners for Justice 2  (Korean drama), features Doctor K, who had Fabry disease. Doc (Italian drama): Series two features an episode with a tennis player who is diagnosed with Fabry disease

See also
Migalastat

References
Further reading
James, William D.; Berger, Timothy G.; Elston, Dirk (2006). Andrews Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 978-0-7216-2921-6. Schiffmann, Raphael; Kopp, Jeffrey B.; Austin, Howard A.; Sabnis, Sharda; Moore, David F.; Weibel, Thais; Balow, James E.; Brady, Roscoe O. (June 2001). "Enzyme replacement therapy in Fabry disease: a randomized controlled trial". JAMA. 285 (21): 2743–2749. doi:10.1001/jama.285.21.2743. PMID 11386930. Wilcox, William R.; Banikazemi, Maryam; Guffon, Nathalie; Waldek, Stephen; Lee, Philip; Linthorst, Gabor E.; Desnick, Robert J.; Germain, Dominique P. (July 2004). "Long-term safety and efficacy of enzyme replacement therapy for Fabry disease". American Journal of Human Genetics. 75 (1): 65–74. doi:10.1086/422366. PMC 1182009. PMID 15154115. External links

Fabry Disease Information Page at NINDS
Fabry disease at NLM Genetics Home Reference