The proponents of mumps as a cause pointed to this as the effect of the recent implementation of widespread mumps immunization.Evidence that viral infection may play a role as a cause or trigger of EFE was greatly reinforced by the study directed by Towbin in the virus laboratory of Texas Childrens Hospital. They applied the methods of todays genetics to old preserved specimens from autopsies of patients with EFE done well before mumps immunization began and found mumps genome in the tissues of over 80% of these patients. It seems undeniable that transplacental mumps infection had been in the past the major cause of EFE, and that immunization was indeed the cause of EFE having become rare.Non-infectious causes of EFE have also been studied, spurred by the opening of new avenues of genetics research. Now there are specific named genes associated with certain cardiomyopathies, some of which show the characteristic reaction of EFE. A typical example is Barth syndrome and the responsible gene, tafazzin.Developments in echocardiography, both the technology of the machines and the skill of the operators, have made it no longer necessary to see the endocardium at autopsy. EFE can now be found non-invasively by the recording of increased endocardial echos.
Transient lingual papillitis  are painful, hypertrophic, red and white lingual papillae on the tongue. Cause
Transient lingual papillitis can affect males and females as early as 3 years of age. In many cases, the cause is unknown. Some dental professionals believe the inflammation is due to chronic irritation from teeth, fillings, or dental appliances. Stress, poor nutrition, smoking, and alcohol use may also be initiating factors. == References ==