The symptoms progress over time, often beginning as a tingling sensation in the ball of the foot.Mortons neuroma lesions have been found using MRI in patients without symptoms. Diagnosis
Negative signs include a lack of obvious deformities, erythema, signs of inflammation, or limitation of movement. Direct pressure between the metatarsal heads will replicate the symptoms, as will compression of the forefoot between the finger and thumb so as to compress the transverse arch of the foot. This is referred to as Mulders sign.There are other causes of pain in the forefoot that often lead to miscategorization as neuroma, such as capsulitis, which is an inflammation of ligaments that surround two bones at the level of the joint. If the ligaments that attach the phalanx (bone of the toe) to the metatarsal bone are impacted, the resulting inflammation may put pressure on an otherwise healthy nerve and produce neuroma-type symptoms. Additionally, an intermetatarsal bursitis between the third and fourth metatarsal bones will also give neuroma-type symptoms because it too puts pressure on the nerve. Freiberg disease, which is an osteochondritis of the metatarsal head, causes pain on weight-bearing or compression. Other conditions that could be clinically confused with a neuroma include stress fractures/reactions and plantar plate disruption. Histopathology
Microscopically, the affected nerve is markedly distorted, with extensive concentric perineural fibrosis. The arterioles are thickened and occlusion by thrombi are occasionally present.
Astasia-abasia refers to the inability to either stand or walk in a normal manner. Astasia refers to the inability to stand upright unassisted. Abasia refers to lack of motor coordination in walking. The term abasia literally means that the base of gait (the lateral distance between the two feet) is inconstant or unmeasurable. When seen in conversion disorder, the gait is bizarre and is not suggestive of a specific organic lesion: often the patient sways wildly and nearly falls, recovering at the last moment. An acquired total inability to stand and walk can be seen in organic neurological diseases, including stroke, Parkinsons disease, damage to the cerebellum, Guillain–Barré syndrome, normal pressure hydrocephalus and many others. In normal pressure hydrocephalus, for example, when the condition remains untreated, the patients gait becomes shortened, with frequent shuffling and falls; eventually standing, sitting, and even rolling over in bed become impossible. This advanced state is referred to as "hydrocephalic astasia-abasia". Phobias
Astasia and/or abasia are  associated with the corresponding fears of walking and/or standing, variously called stasophobia, basophobia, stasiphobia, basiphobia, stasobasophobia, stasibasiphobia, etc., sometimes turning into pathological forms, i.e., phobias. See also
Blocqs disease, an illness named after Paul Oscar Blocq

References


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