It is also one of several antibacterial drugs recommended for the treatment of infections known to be caused by anaerobic Gram-negative rods.Piperacillin-tazobactam is recommended by the National Institute for Health and Care Excellence as initial empiric treatment for people with suspected neutropenic sepsis.Piperacillin is used to treat patients diagnosed with various internal infections such as abdominal, bacteremia, gynecological, respiratory, and urinary, mainly caused by Pseudomonas aeruginosa and other infectious bacteria. They are primarily used in current and former neutropenic patients, and patients with biliary tract infections. Other uses include applications in surgical infection prophylaxis; in biliary surgery, a single dose of piperacillin is administered intravenously to inhibit the development of acute cholangitis and prevent wound infections. The combination of piperacillin and an aminoglycoside is commonly used to treat severe infections, but due to the incompatibilities in drug interaction, they are administered separately. Pneumonia
The piperacillin-tazobactam (piptaz) antibiotic commonly used with an aminoglycoside retains similar levels of drug safety and efficacy as other antibiotic combinations such as ceftazidime with the aminoglycoside tobramycin in the treatment of patients with hospital acquired pneumonia. In a clinical comparison primarily targeting patients not initially placed in intensive care units, piperacillin-tazobactam was found to produce higher clinical and microbiological rates of success. By contrast, the drug efficacy of ceftazidime and piperacillin-tazobactam resulted in similar response rates (61.5% and 63.9 respectively) when tobramycin was added into both groups.
The presumed source of infections was one of the family’s  four Labrador retrievers, two of which were found to already have been infected with D. caninum. The second additional case occurred in an 18-month-old male. Mother found motile proglottids in the child’s diaper and again, the child was symptom-free. A puppy in the household was found to be infected and thus was the source of the child infection. Young children and toddlers are at a greater risk of infection because of how they interact with their pets. A human may attain an infection by accidentally ingesting an infected flea through food contamination or through the saliva of pets. Most infections are asymptomatic, but sometimes these symptoms may be identified in an infected individual: mild diarrhea, abdominal colic, anorexia, restlessness, constipation, rectal itching, and pain due to emerging proglottids through the anal cavity. Treatment and prevention
As with most tapeworm infections, the drugs of choice to kill adult tapeworms are praziquantel or niclosamide. Pets can be prevented from becoming infested with tapeworm if they are treated prophylactically with a product which kills the intermediate host (the flea) before the infective metacestode can develop. Some isoxazoline products are registered to prevent flea tapeworm infestations using this method. Gallery
References
External links
tapeworms from The Pet Health Library