The first inactive tetanus toxoid was discovered and produced in 1924. A more effective adsorbed version of the vaccine, created in 1938, was proven to be successful when it was used to prevent tetanus in the military during World War II. DTP (which is the combined vaccine for diphtheria, tetanus, and pertussis) was first used in 1948, and was continued until 1991, when it was replaced with an acellular form of the pertussis vaccine due to safety concerns. Half of those who received the DTP vaccine had redness, swelling, and pain around the injection site, which convinced researchers to find a replacement vaccine. Two new vaccines were launched in 1992. These combined tetanus and diphtheria with acellular pertussis (TDaP or DTaP), which could be given to adolescents and adults (as opposed to previously when the vaccine was only given to children). References
Further reading
Liang JL, Tiwari T, Moro P, Messonnier NE, Reingold A, Sawyer M, Clark TA (April 2018). "Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP)" (PDF). MMWR Recomm Rep. 67 (2): 1–44. doi:10.15585/mmwr.rr6702a1. ISSN 1057-5987. PMC 5919600. PMID 29702631. Kahn KE, Black CL, Ding H, Williams WW, Lu PJ, Fiebelkorn AP, Havers F, DAngelo DV, Ball S, Fink RV, Devlin R (September 2018). "Influenza and Tdap Vaccination Coverage Among Pregnant Women - United States, April 2018" (PDF). MMWR Morb. Mortal. Wkly. Rep. 67 (38): 1055–1059. doi:10.15585/mmwr.mm6738a3. PMC 6188122. PMID 30260946. World Health Organization (2018).
In 2014, the global market for deodorants was estimated at US$13.00 billion with a compound annual growth rate of 5.62% between 2015 and 2020. Medical conditions
Osmidrosis or bromhidrosis is defined by a foul odor due to a water-rich environment that supports bacteria, which is caused by an abnormal increase in perspiration (hyperhidrosis). This can be particularly strong when it happens in the axillary region (underarms). In this case, the condition may be referred to as axillary osmidrosis. The condition can also be known medically as apocrine bromhidrosis, ozochrotia, fetid sweat, body smell, or malodorous sweating.Trimethylaminuria (TMAU), also known as fish odor syndrome or fish malodor syndrome, is a rare metabolic disorder where trimethylamine is released in the persons sweat, urine, and breath, giving off a strong fishy odor or strong body odor. See also
References
External links
Flores, Graciela (November 4, 2004). "Immunity, smell linked". The Scientist Magazine.