The provisional representation of species addressed by the resource has been indicated in the TaxBox on this page by a superscript yb beside the species name. Development of YersiniaBase was funded by the University of Malaya and the Ministry of Education, Malaysia. Pathogenesis
Y. pestis is the causative agent of plague. The disease caused by Y. enterocolitica is called yersiniosis. Yersinia may be associated with Crohns disease, an inflammatory autoimmune condition of the gut. Iranian sufferers of Crohns disease were more likely to have had earlier exposure to refrigerators at home, consistent with its unusual ability to thrive at low temperatures. Yersinia is implicated as one of the causes of reactive arthritis worldwide.Also, the genus is associated with pseudoappendicitis, which is an incorrect diagnosis of appendicitis due to a similar presentation. History
Y. pestis, the first known species, was identified in 1894 by A.E.J. Yersin, a Swiss bacteriologist, and Kitasato Shibasaburō, a Japanese bacteriologist. It was formerly described as Pasteurella pestis (known trivially as the plague-bacillus) by Lehmann and Neumann in 1896. In 1944, van Loghem reclassified the species P. pestis and P. rondentium into a new genus, Yersinia. Following the introduction of the bacteriological code, it was accepted as valid in 1980. References
External links
Yersinia Enterocolitis Mimicking Crohns Disease in a Toddler
Sweden: Pork warnings over new stomach illness
Yersinia genomes and related information at PATRIC, a Bioinformatics Resource Center funded by NIAID
YersiniaBase
This is in order to allow production of normal basement membrane and division of normal epithelium. Often further treatment is necessary, such as a keratotomy, which is superficial cutting or piercing of the cornea. There are two main types used in dogs: multiple punctate keratotomy (MPK) and grid keratotomy (GK). MPK involves making small superficial punctures into the cornea with a needle. GK is more commonly used and involves making parallel and perpendicular scratches in the corneal surface. Usually only topical anesthesia is necessary. By scoring the corneal surface, anchoring points are provided for attachment of new epithelium. Of course, these procedures should only be performed by a veterinarian, particularly one with some experience in this treatment. Complete healing takes about three to four weeks. Keratotomies may lead to corneal sequestration in cats. Other medications have been shown to be useful in topical treatment of refractory ulcers, including glycosaminoglycans such as sodium hyaluronate and chondroitin sulfate, aminocaproic acid, and acetylcysteine. Melting ulcers
Melting ulcers are a type of corneal ulcer involving progressive loss of stroma in a dissolving fashion. This is most commonly seen in Pseudomonas infection, but it can be caused by other types of bacteria or fungi. These infectious agents produce proteases and collagenases which break down the corneal stroma. Complete loss of the stroma can occur within 24 hours. Treatment includes antibiotics and collagenase inhibitors such as acetylcysteine and homologous blood serum. Surgery may be necessary.