Criteria
Classification with APS requires evidence of both one or more specific, documented clinical events (either a vascular thrombosis and/or adverse obstetric event) and the confirmed presence of a repeated aPL. The Sapporo APS classification criteria (1998, published in 1999) were replaced by the Sydney criteria in 2006.
Diagnosis
Differential diagnosis
The main differential diagnosis is scarlet fever. History
The first outbreak of this disease was reported from the Pacific coastal areas (Primorsky Krai) of Russia in the 1950s. == References ==