Recognised patterns of clinical features include respiratory, eye, gastrointestinal, genitourinary and central nervous system. There is also a widespread type that occurs in immunocompromised people. Typical symptoms are of a mild cold or resembling the flu; fever, nasal congestion, coryza, cough, and pinky-red eyes. Infants may also have symptoms of an ear infection. Onset is usually two to fourteen days after exposure to the virus. There may be tiredness, chills, muscle aches, or headache. However, some people have no symptoms. Generally, a day or two after developing a sore throat with large tonsils, glands can be felt in the neck. Illness is more likely to be severe in people with weakened immune systems, particularly children who have had a hematopoietic stem cell transplantation. Sometimes there is a skin rash. Respiratory tract
Preschool children with adenovirus colds tend to present with a nasal congestion, runny nose and abdominal pain. There may be a harsh barking cough. It is frequently associated with a fever and a sore throat. Up to one in five infants with bronchiolitis will have adenovirus infection, which can be severe. Bronchiolitis obliterans is uncommon, but can occur if adenovirus causes pneumonia with prolonged fever, and can result in difficulty breathing. It presents with a hyperinflated chest, expiratory wheeze and low oxygen. Severe pneumonia is most common in very young children age three-to-18 months and presents with sudden illness, ongoing cough, high fever, shortness of breath and a fast rate of breathing. There are frequently wheezes and crackles on breathing in and out.
Previous terminology
Sexual sadism is the term previously employed by the DSM-III-R, DSM-IV, and DSM-IV-TR, where it was classified as a paraphilia. In these versions of the DSM, sexual sadism pertained only to the infliction of real (not simulated) suffering (p. 530). The condition was renamed sexual sadism disorder in DSM-5. Sexual sadism was the term employed in the DSM-III, classifying the condition as a paraphilia. The DSM-III noted that "the imagery in a Paraphilia, such as simulated bondage, may be playful and harmless and acted out with a mutually consenting partner….In more extreme form, paraphilic imagery is acted out with a nonconsenting partner, and is noxious and injurious to the partner" (p. 267). In DSM-III, sexual sadism could be diagnosed if:

the person repeatedly and intentionally inflicted suffering on a nonconsenting person, to experience sexual excitement
repeatedly or exclusively preferred simulated or mild suffering with a consenting sexual partner
employs extensive, permanent, or potentially fatal suffering to achieve sexual excitement, regardless of the consent of the other person.Sadism was the term employed by the DSM-II. In that manual, the condition was classified as a sexual deviation, which was used to describe "individuals whose sexual interests are directed primarily toward…coitus performed under bizarre circumstances" (p. 44). The term "paraphilia" did not exist in the DSM-II, and diagnoses did not have specific criteria until DSM-III. Sexual sadism was the phrase mentioned in DSM-I as one of the sexual deviations (p. 39), but neither it (nor any of the other sexual deviations) received a specific label or diagnostic criteria.