Primary pulmonary coccidioidomycosis is an infection caused by inhalation of Coccidioides immitis. : 314   Once pulmonary symptoms subside, about 30% of women and 15% of men will have allergic skin manifestations in the form of erythema nodosum. : 314  A coccidioidoma is a benign localized residual granulomatous lesion or scar that can remain in the lungs tissues following primary pulmonary coccidioidomycosis. See also
Coccidioidomycosis
List of cutaneous conditions


== References ==
Grovers disease (GD) is a polymorphic, pruritic, papulovesicular dermatosis characterized histologically by acantholysis: 529  with or without dyskeratosis. Once confirmed, most cases of Grovers disease last six to twelve months, which is why it was originally called "transient". However it may last much longer. Nevertheless, it is not to be confused with relapsing linear acantholytic dermatosis. Signs and symptoms
Grovers disease often starts quite suddenly. There are intensely itchy spots on the central back, mid chest and occasionally elsewhere. Frequently, it follows sweating or some unexpected heat stress. The itchy eruption lasts an average of 10–12 months. It is characterized by papules and papulovesicles with excoriations occurring on the chest, back, lower sternum, arms, and thighs. The papules are most commonly found on the mid chest. Sometimes the features of Grovers are found in people who do not itch or have a conspicuous rash. Most of the people with Grovers who visit a dermatologist, however, itch a lot. Cause
The cause of Grovers disease is unknown. Suspected triggers of disease activity include heat and sweating, sunlight, and adverse reaction to medications: 24  as well as ionizing radiation, end-stage renal disease/hemodialysis, and mechanical irritation or prolonged bed rest. Some cases of Grovers disease have been associated with medications such as sulfadoxine-pyrimethamine, ribavirin, cetuximab, and interleukin-4 [1,8-15]. One series of 300 patients with Grovers disease reported an association with other coexisting dermatoses including atopic dermatitis, contact dermatitis, and xerosis cutis. Finally, smaller series have detailed an association with pyoderma gangrenosum, bacterial and viral infections, and occasionally, malignancies.