Primary hyperoxaluria is a rare condition (autosomal recessive), resulting in increased excretion of oxalate (up to 600 mg a day from normal 50 mg a day), with oxalate stones being common. Signs and symptoms
Primary hyperoxaluria is an autosomal recessive disease, meaning both copies of the gene contain the mutation. Both parents must have one copy of this mutated gene to pass it on to their child, but they do not typically show signs or symptoms of the disease. A single kidney stone in children or recurrent stones in adults is often the first warning sign of primary hyperoxaluria. Other symptoms range from recurrent urinary tract infections, severe abdominal pain or pain in the side, blood in the urine, to chronic kidney disease and kidney failure. The age of symptom onset, progression and severity can vary greatly from one person to another, even among members of the same family. Some individuals may have mild cases that go undiagnosed well into adulthood; others may develop severe complications during infancy, which may result in early death. Pathophysiology
The buildup of oxalate in the body causes increased renal excretion of oxalate (hyperoxaluria), which in turn results in kidney and bladder stones. Stones cause urinary obstruction (often with severe and acute pain), secondary infection of urine and eventually kidney damage. Primary hyperoxaluria is caused by genetic defects that result in the overproduction of oxalate.
Admission may refer to:

Arts and media
"Admissions" (CSI: NY), an episode of CSI: NY
Admissions (film), a 2011 short film starring James Cromwell
Admission (film), a 2013 comedy film
Admission, a 2019 album by Florida sludge metal band Torche
Admission (novel), a 2020 novel by Julie Buxbaum

Legal proceedings
Admission (law), a statement that may be used in court against the person making it
Acceptance of admissible evidence in court
The process of official inclusion in a state, the opposite of secession

Status granted to a person
University and college admission
Admission to the bar, change in status allowing an applicant to become part of a profession

Other uses
The process by which patients enter into inpatient care
Admittance, the inverse of impedance

See also
Admissibility (disambiguation)
List of U.S. states by date of admission to the Union