Diagnosis
Diagnosis should be based on the clinical and radiographic findings and a genetic analysis can be assessed. Treatment
Symptomatic individuals should be seen by an orthopedist to assess the possibility of treatment (physiotherapy for muscular strengthening, cautious use of analgesic medications such as nonsteroidal anti-inflammatory drugs). Although there is no cure, surgery is sometimes used to relieve symptoms. Surgery may be necessary to treat misalignment of the hip (osteotomy of the pelvis or the collum femoris) and, in some cases, malformation (e.g., genu varum or genu valgum). In some cases, total hip replacement may be necessary. However, surgery is not always necessary or appropriate.Sports involving joint overload are to be avoided, while swimming or cycling are strongly suggested. Cycling has to be avoided in people having ligamentous laxity. Weight control is suggested.The use of crutches, other deambulatory aids or wheelchair is useful to prevent hip pain. Pain in the hand while writing can be avoided using a pen with wide grip. History
Multiple epiphyseal dysplasia was described separately by Seved Ribbing and Harold Arthur Thomas Fairbank in the 1930s.In 1994, Ralph Oehlmanns group mapped MED to the peri-centromeric region of chromosome 19, using genetic linkage analysis. Michael Briggs group mapped PSACH to the same area. COMP gene was firstly linked to MED and PSACH in 1995. In 1995, the group led by Knowlton did a "high-resolution genetic and physical mapping of multiple epiphyseal dysplasia and pseudoachondroplasia mutations at chromosome 19p13.1-p12. "Research on COMP led to mouse models of the pathology of MED.
Site most often refers to:

Archaeological site
Campsite, a place used for overnight stay in an outdoor area
Construction site
Location, a point or an area on the Earths surface or elsewhere
Website, a set of related web pages, typically with a common domain nameIt may also refer to:

Site, a National Register of Historic Places property type
SITE (originally known as Sculpture in the Environment), an American architecture and design firm
Site (mathematics), a category C together with a Grothendieck topology on C
The Site, a 1990s TV series that aired on MSNBC
SITE Intelligence Group, a for-profit organization tracking jihadist and white supremacist organizations
SITE Institute, a terrorism-tracking organization, precursor to the SITE Intelligence Group
Sindh Industrial and Trading Estate, a company in Sindh, Pakistan
SITE Centers, American commercial real estate company
SITE Town, a densely populated town in Karachi, Pakistan
S.I.T.E Industrial Area, an area in Karachi, Pakistan
Satellite Instructional Television Experiment, an experimental satellite communications project launched in India in 1975
Google Sites, web based website editor

See also
Sites, California
All pages with titles beginning with Site
All pages with titles containing Site