The human leg, in the general word sense, is the entire lower limb of the human body, including the foot, thigh or sometimes even the hip or gluteal region. However, the definition in human anatomy refers only to the section of the lower limb extending from the knee to the ankle, also known as the crus or, especially in non-technical use, the shank. Legs are used for standing, and all forms of locomotion including recreational such as dancing, and constitute a significant portion of a persons mass. Female legs generally have greater hip anteversion and tibiofemoral angles, but shorter femur and tibial lengths than those in males. Structure
In human anatomy, the lower leg is the part of the lower limb that lies between the knee and the ankle. Anatomists restrict the term leg to this use, rather than to the entire lower limb. The thigh is between the hip and knee and makes up the rest of the lower limb. The term lower limb or lower extremity is commonly used to describe all of the leg. The leg from the knee to the ankle is called the crus. The calf is the back portion, and the tibia or shinbone together with the smaller fibula make up the front of the lower leg. Evolution has provided the human body with two distinct features: the specialization of the upper limb for visually guided manipulation and the lower limbs development into a mechanism specifically adapted for efficient bipedal gait.
It is also useful for preventing hyperammonemia caused as a side effect of administration of valproic acid. Small intestine bacterial overgrowth
Lactulose is used as a test of small intestine bacterial overgrowth (SIBO). Recently, the reliability of it for diagnosing SIBO has been seriously questioned. A large amount of it is given with subsequent testing of molecular hydrogen gas in the breath. The test is positive if an increase in exhaled hydrogen occurs before that which would be expected by normal  digestion by the normal gut flora in the colon. An earlier result has been hypothesized to indicate digestion occurring within the small intestine. An alternate explanation for differences in results is the variance in small bowel transit time among tested subjects. Pregnancy
No evidence of harm to the baby has been found when used during pregnancy. It is generally regarded as safe during breastfeeding. Side effects
Common side effects of lactulose are abdominal cramping, borborygmus, and flatulence. In normal individuals, overdose is considered uncomfortable, but not life-threatening. Uncommon side effects are nausea and vomiting. In sensitive individuals, such as the elderly or people with reduced kidney function, excess lactulose dosage can result in dehydration and electrolyte disturbances such as low magnesium levels. Ingestion of lactulose does not cause a weight gain because it is not digestible, with no nutritional value. Although lactulose is less likely to cause dental caries than sucrose, as a sugar, a potential for this exists. This should be taken into consideration when taken by people with a high susceptibility to this condition.