Plato believed that time was made by the Creator at the same instant as the heavens. He also says that time is a period of motion of the heavenly bodies. Aristotle believed that time correlated to movement, that time did not exist on its own but was relative to motion of objects. he also believed that time was related to the motion of celestial bodies; the reason that humans can tell time was because of orbital periods and therefore there was a duration on time.The Vedas, the earliest texts on Indian philosophy and Hindu philosophy dating back to the late 2nd millennium BC, describe ancient Hindu cosmology, in which the universe goes through repeated cycles of creation, destruction and rebirth, with each cycle lasting 4,320 million years.Ancient Greek philosophers, including Parmenides and Heraclitus, wrote essays on the nature of time.Plato, in the Timaeus, identified time with the period of motion of the heavenly bodies. Aristotle, in Book IV of his Physica defined time as number of movement in respect of the before and after.In Book 11 of his Confessions, St. Augustine of Hippo ruminates on the nature of time, asking, "What then is time? If no one asks me, I know: if I wish to explain it to one that asketh, I know not." He begins to define time by what it is not rather than what it is,
an approach similar to that taken in other negative definitions.
Monocytosis is an increase in the number of monocytes circulating in the blood. Monocytes are white blood cells that give rise to macrophages and dendritic cells in the immune system. In humans, monocytosis occurs when there is a sustained rise in monocyte counts greater than 800/mm3 to 1000/mm3.Monocytosis has sometimes been called mononucleosis, but that name is usually reserved specifically for infectious mononucleosis. Causes
Monocytosis often occurs during chronic inflammation. Diseases that produce such a chronic inflammatory state:
Infections: tuberculosis, brucellosis, listeriosis, subacute bacterial endocarditis, syphilis, and other viral infections and many protozoal and rickettsial infections (e.g. kala azar, malaria, Rocky Mountain spotted fever). Blood and immune causes: chronic neutropenia and myeloproliferative disorders. Autoimmune diseases and vasculitis: systemic lupus erythematosus, rheumatoid arthritis and inflammatory bowel disease. Malignancies: Hodgkins disease and certain leukaemias, such as chronic myelomonocytic leukaemia (CMML) and monocytic leukemia. Recovery phase of neutropenia or an acute infection. Obesity (cf. Nagareddy et al. (2014), Cell Metabolism, Vol. 19, pp 821–835)
Miscellaneous causes: sarcoidosis, lipid storage disease and ZNFX1 deficiency.During these stages of extreme inflammation, monocytosis can damage tissues because it increases the activation of the immune response and prevents the inflammation from subsiding which is seen in cases where sepsis occurs. Diagnosis
Blood Test (CBC) (Normal range of Monocytes: 1-10%) (Normal range in males: 0.2-0.8 x 103/microliter)
Blood test checking for monocytosis (Abnormal ranges: >10%) (Abnormal range in males: >0.8 x 103/microliter)

Treatment
Ceftriaxone if there is typhoid fever and levofloxacin or moxifloxacin. Gentamicin and doxycyclin if brucellosis. References


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