More recently, however, a meta-analysis has shown that overall cancer rates are barely increased with an odds ratio of 1.07, which suggests that an impact on mortality from cancer is small or zero. Epidemiology
The prevalence of 677T homozygosity varies with race. 18-21% of Hispanics and Southern Mediterranean populations have this variant, as do 6-14% of North American Whites and <2% of Blacks living outside of Africa. The prevalence of the 1298C mutation is lower, at 4-12% for most tested populations.A study in 2000 had identified only 24 cases of severe MTHFR deficiency (from nonsense mutations) across the whole world. See also
Hyperhomocysteinemia
Homocystinuria
Cystathionine beta synthase

References


== External links ==
Calcinosis is the formation of calcium deposits in any soft tissue. It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure. Types
Dystrophic calcification
The most common type of calcinosis is dystrophic calcification. This type of calcification can occur as a response to any soft tissue damage, including that involved in implantation of medical devices. Metastatic calcification
Metastatic calcification involves a systemic calcium excess imbalance, which can be caused by hypercalcemia, kidney failure, milk-alkali syndrome, lack or excess of other minerals, or other causes. Tumoral calcinosis
The cause of the rare condition of tumoral calcinosis is not entirely understood. It is generally characterized by large, globular calcifications near joints. See also
Calcification
Calcinosis cutis
Dermatomyositis
Fahrs syndrome
Hyperphosphatemia
Primrose syndrome
Scleroderma

References
External links
 Media related to Calcinosis at Wikimedia Commons