Essentially, rectal prolapses may be:
full thickness (complete), where all the layers of the rectal wall prolapse, or involve the mucosal layer only (partial)
external  if they protrude from the anus and are visible externally, or internal if they do not
circumferential, where the whole circumference of the rectal wall prolapse, or segmental if only parts of the circumference of the rectal wall prolapse
present at rest, or occurring during straining.External (complete) rectal prolapse (rectal procidentia, full thickness rectal prolapse, external rectal prolapse) is
a full thickness, circumferential, true intussusception of the rectal wall which protrudes from the anus and is visible externally.Internal rectal intussusception (occult rectal prolapse, internal procidentia) can be defined as a funnel shaped infolding of the upper rectal (or lower sigmoid) wall that can occur during defecation. This infolding is perhaps best visualised as folding a sock inside out, creating "a tube within a tube". Another definition is "where the rectum collapses but does not exit the anus". Many sources differentiate between internal rectal intussusception and mucosal prolapse, implying that the former is a full thickness prolapse of rectal wall. However, a publication by the American Society of Colon and Rectal Surgeons stated that internal rectal intussusception involved the mucosal and submucosal layers separating from the underlying muscularis mucosa layer attachments, resulting in the separated portion of rectal lining "sliding" down. This may signify that authors use the terms internal rectal prolapse and internal mucosal prolapse to describe the same phenomena.
Fixed drug reactions,  are common and so named because they recur at the same site with each exposure to a particular medication. Medications inducing fixed drug eruptions are usually those taken intermittently. Signs and symptoms
A painful and itchy reddish/purple patch of skin that occurs in the same location with repeated exposures to the culprit drug is the classic presentation of a fixed drug reaction. The lips, genitals, and hands are often involved. Cause
Medications that are commonly implicated as a cause of fixed drug eruptions include the following:

Cetirizine
Ciprofloxacin
Clarithromycin
Cotrimoxazole
Doxycycline
Fluconazole
NSAIDs (e.g., ibuprofen, etoricoxib, naproxen)
Phenytoin
Pseudoephedrine
Trimethoprim

See also
Drug eruption
List of cutaneous conditions
List of human leukocyte antigen alleles associated with cutaneous conditions
Stevens–Johnson syndrome

References


== External links ==