Removal or enucleation of the eye is a last resort option if the eye already has become blind and painful.Repeated blood transfusions may be needed to control anemia, and thrombocytopenia can be managed with splenectomy. Prognosis
The neurological symptoms are progressive and can lead to severe spasticity, bulbar symptoms and dysarthria within one to two decades. The life span is shorter than normal. Death occurs between 2 and 30 years of age, depending on the severity of the syndrome. The immediate cause of death is pneumonia, fulminant intestinal bleeding or multiple organ dysfunction.If not treated, the retinal detachment can lead to ischemia and growth of new blood vessels over the iris and anterior chamber angle. This in turn can cause secondary glaucoma, cataract and, ultimately, blindness of the eye. Epidemiology
This syndrome is usually sporadic although families with two or more affected siblings of both sexes are known. History
A child who was eventually diagnosed with cerebroretinal microangiopathy with calcifications and cysts was first described in the literature in 1987. The disorder was suspected of being allelic with either the Revesz syndrome or leukoencephalopathy with calcifications and cysts.
Dissociation, in the wide sense of the word, is an act of disuniting or separating a complex object into parts. Dissociation may also refer to:

Dissociation (chemistry), general process in which molecules or ionic compounds (complexes, or salts) split into smaller particles, usually in a reversible manner
Dissociation (neuropsychology), identification of the neural substrate of a particular brain function through various methods
Dissociation (psychology), an experience of having ones attention and emotions detached from the environment
Dissociation (rhetoric), a rhetorical device in which the speaker separates a notion considered to form a unitary concept into two new notions to affect an audience in some way
Dissociation (album), by the Dillinger Escape Plan, 2016

See also
Dissociation: Progress in the Dissociative Disorders (1988-1997) published by International Society for the Study of Trauma and Dissociation
"Disassociation", a 2021 song by the Rions
Dissociative, a class of hallucinogen
All pages with titles beginning with Dissociation
All pages with titles containing Dissociation