Relapse rate has been recorded as high as 50%. Many children have been brought into remission after a second stem cell transplant.After bone marrow transplant, the relapse rate for children with JMML may be as high as 50%. Relapse often occurs within a few months after transplant and the risk of relapse drops considerably at the one-year point after transplant. A significant number of JMML patients do achieve complete remission and long-term cure after a second bone marrow transplant, so this additional therapy should always be considered for children who relapse. Frequency
JMML accounts for 1–2% of childhood leukemias each year; in the United States, an estimated 25-50 new cases are diagnosed each year, which also equates to about 3 cases per million children. There is no known environmental cause for JMML. Since about 10% of patients are diagnosed before 3 months of age, it is thought that JMML is a congenital condition in these infants

History
Juvenile myelomonocytic leukemia (JMML) is a myelodysplastic and myeloproliferative disorder. The diagnostic criteria were originally laid down by Neimeyer et al. in 1997 and 1998 and were incorporated in the WHO classification in 2008. See also
List of cutaneous conditions
Hematologic disease
List of cancer types

References


== External links ==
Eastern Christianity
Archpriest, also protopope (Greek: πρωτοπαπᾶς, protopapas) or protopresbyter (Greek: πρωτοπρεσβύτερος, protopresbyteros), is a clerical rank, a title of honor given to non-monastic priests and is conferred by a bishop with the laying on of hands and prayer. An archpriest typically wears an epigonation, a vestment originally worn only by bishops; however, details vary locally, and in some places being given the epigonation is an honor that typically precedes being made an archpriest and in other places, it is an honor that is given to only some archpriests. An archpriest also wears a pectoral cross both as part of his street clothes and when vested. The ceremony for making an archpriest is analogous to other clerical promotions bestowed with cheirothesia: at the little entrance of the divine liturgy, the candidate is conducted to the ambo in the middle of the church where the bishop is at the time, and the bishop blesses him and says a prayer addressed to Christ asking to "... endue our brother (name) with Thy Grace, and adorn him with virtue to stand at the head of the Presbyters of Thy people, and make him to be a good example to them that are with him ..."In the Russian tradition, protopresbyter is a higher rank than archpriest, as explained in a translation by the Orthodox Church in America:

Although entitled "for the making of a Protopresbyter" it is clear that what is now known as an "Archpriest" is what is usually meant.