The FDA approved dexmedetomidine for use in dogs in 2006 and cats in 2007.In 2015, the European Medicines Agency and the FDA approved an oromucosal gel form of dexmedetomidine marketed as Sileo (Zoetis) for use in dogs for relief of noise aversion. References
External links
"Dexmedetomidine". Drug Information Portal. U.S. National Library of Medicine. "Dexmedetomidine hydrochloride". Drug Information Portal. U.S. National Library of Medicine.
Zoonosis, pasteurellosis can be transmitted to humans through cats.Other locations are possible, such as septic arthritis, meningitis, and acute endocarditis, but are very rare. Diagnosis
Diagnosis is made with isolation of Pasteurella multocida in a normally sterile site (blood, pus, or cerebrospinal fluid). Treatment
As the infection is usually transmitted into humans through animal bites, antibiotics usually treat the infection, but medical attention should be sought if the wound is severely swelling. Pasteurellosis is usually treated with high-dose penicillin if severe. Either tetracycline or chloramphenicol provides an alternative in beta-lactam-intolerant patients. However, it is most important to treat the wound. Animals
P. multocida causes numerous pathological conditions in domestic animals. It often acts with other infectious agents, such as  Chlamydia and Mycoplasma species and viruses. Environmental conditions (transportation, housing deficiency, and bad weather) also play a role. These diseases are considered caused by P. multocida, alone or associated with other pathogens:

Shipping fever in cattle and sheep  ("shipping fever" may also be caused by Mannheimia haemolytica, in the absence of P. multocida, and M. haemolytica serovar A1 is known as the most common cause of the disease. The pathologic condition commonly arises where the causative organism becomes established by secondary infection, following a primary bacterial or viral infection, which may occur after stress, e.g. from handling or transport.)