Recent WHO seasonal influenza vaccine composition recommendations:

2020–2021 northern hemisphere
The composition of virus vaccines for use in the 2020–2021 Northern Hemisphere influenza season recommended by the World Health Organization on February 28, 2020, is:for egg-based:

an A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus
an A/Hong Kong/2671/2019 (H3N2)-like virus
a B/Washington/02/2019 (B/Victoria lineage)-like virus
a B/Phuket/3073/2013 (B/Yamagata lineage)-like virusfor cell- or recombinant-based:
an A/Hawaii/70/2019 (H1N1)pdm09-like virus
an A/Hong Kong/45/2019 (H3N2)-like virus
a B/Washington/02/2019 (B/Victoria lineage)-like virus
a B/Phuket/3073/2013 (B/Yamagata lineage)-like virusThe WHO recommends that trivalent vaccines use as their influenza B virus a B/Washington/02/2019 (B/Victoria lineage)-like virus. United StatesThe Vaccines and Related Biological Products Advisory Committee (VRBPAC) of the Food and Drug Administration (FDA) recommended that the quadrivalent formulation of egg-based influenza vaccines for the US 2020–2021 influenza season contain the following:
an A/Guangdong-Maonan/SWL1536/2019 (H1N1)pdm09-like virus;
an A/HongKong/2671/2019 (H3N2)-like virus;
a B/Washington/02/2019-like virus (B/Victoria lineage);
a B/Phuket/3073/2013-like virus (B/Yamagata lineage).The committee recommended that the quadrivalent formulation of cell- or recombinant-based influenza vaccines for the US 2020–2021 influenza season contain the following:
an A/Hawaii/70/2019 (H1N1)pdm09-like virus;
an A/HongKong/45/2019 (H3N2)-like virus;
a B/Washington/02/2019-like virus (B/Victoria lineage);
a B/Phuket/3073/2013-like virus (B/Yamagata lineage)For trivalent influenza vaccines for use in the US for the 2020–2021 influenza season, depending on the manufacturing method of the vaccine, the committee recommended that the A(H1N1)pdm09, A(H3N2) and B/Victoria lineage viruses recommended above for the quadrivalent vaccines be used.
Pili torti (singular pilus tortus; also known as "twisted hairs") is characterized by short and brittle hairs that appear flattened and twisted when viewed through a microscope. : 638 : 764 This phenotype is noted in Menkes disease and Lichen planopilaris. Pili torti can also occur after use of retinoids, such as isotretinoin. See also
List of cutaneous conditions
Crandall syndrome

References


== External links ==