For individuals who begin to experience same-sex attraction, familial support and acceptance consistently predicts positive outcomes. Parents and guardians can support preadolescents, regardless of sexual orientation, by having honest conversations about sex. Specifically, parents can talk and listen in a way that invites preadolescents to have an open discussion about sexual orientation. Home from home
Where development has been optimal, preadolescents come to school for something to be added to their lives; they want to learn lessons...which can lead to their eventually working in a job like their parents. When earlier developmental stages have gone astray, however, then, on the principle that if you miss a stage, you can always go through it later, some middle children come to school for another purpose...[not] to learn but to find a home from home...a stable emotional situation in which they can exercise their own emotional liability, a group of which they can gradually become a part. Divorce
Children at the threshold of adolescence in the nine-to-twelve-year-old group would seem to have particular vulnerabilities to parental separation. Among such problems were the very "eagerness of these youngsters to be co-opted into the parental battling; their willingness to take sides...and the intense, compassionate, caretaking relations which led these youngsters to attempt to rescue a distressed parent often to their own detriment". Media
Preadolescents may well be more exposed to popular culture than younger children and have interests based on internet trends, television shows and movies (no longer just cartoons), fashion, technology, music and social media.
The underlying mechanism is that, with the GnRH antagonist protocol, initial follicular recruitment and selection is undertaken by endogenous endocrine factors prior to starting the exogenous hyperstimulation, resulting in a smaller number of growing follicles when compared with the standard long GnRH agonist protocol.A Cochrane review found administration of hydroxyethyl starch decreases the incidence of severe OHSS. There was insufficient evidence to support routine cryopreservation and insufficient evidence for the relative merits of intravenous albumin versus cryopreservation. Also, coasting, which is ovarian hyperstimulation without induction of final maturation, does not significantly decrease the risk of OHSS.Volume expanders such as albumin and hydroxyethyl starch solutions act providing volume to the circulatory system

Treatment
Treatment of OHSS depends on the severity of the hyperstimulation. Mild OHSS can be treated conservatively with monitoring of abdominal girth, weight, and discomfort on an outpatient basis until either conception or menstruation occurs. Conception can cause mild OHSS to worsen in severity.Moderate OHSS is treated with bed rest, fluids, and close monitoring of labs such as electrolytes and blood counts. Ultrasound may be used to monitor the size of ovarian follicles. Depending on the situation, a physician may closely monitor a womens fluid intake and output on an outpatient basis, looking for increased discrepancy in fluid balance (over 1 liter discrepancy is cause for concern). Resolution of the syndrome is measured by decreasing size of the follicular cysts on 2 consecutive ultrasounds.Aspiration of accumulated fluid (ascites) from the abdominal/pleural cavity may be necessary, as well as opioids for the pain.