This is because Horners syndrome and oculomotor nerve lesions both cause ptosis. Anisocoria is usually a benign finding, unaccompanied by other symptoms (physiological anisocoria). Old face photographs of patients often help to diagnose and establish the type of anisocoria. It should be considered an emergency if a patient develops acute onset anisocoria. These cases may be due to brain mass lesions which cause oculomotor nerve palsy. Anisocoria in the presence of confusion, decreased mental status, severe headache, or other neurological symptoms can forewarn a neurosurgical emergency. This is because a hemorrhage, tumor or another intracranial mass can enlarge to a size where the third cranial nerve (CN III) is compressed, which results in uninhibited dilatation of the pupil on the same side as the lesion. Popular culture
English singer David Bowie exhibited anisocoria, owing to a teenage injury. In the season 10 Big Bang Theory Comic-Con special, Steve Molaro told a story about how he first met actor Judd Hirsch and was taken aback by his dilated pupil. One of the other writers researched it and discovered that Judd Hirsch has anisocoria. American actress Melissa Benoist developed this condition in 2015. American artist Ze Frank has the condition. He was listed as second author on a paper published in The Journal of Neuroscience, which was featured briefly in episode 21 of the show named a show on May 25, 2012 called My Pupils, explaining that his study of neuroscience of vision was motivated by his harmless anisocoria condition.
Etymology
Anisocoria is composed of prefix, root and suffix:

prefix: aniso- from the Greek language (meaning: unequal), which in turn comes from an: meaning not and iso: meaning equal
the root word: cor, from the Greek word "korē" meaning: pupil of the eye
-ia, which is a Latin suffix meaning: disease; pathological or abnormal conditionThus, anisocoria means the condition of unequal pupil(s). See also
Cycloplegia
Miosis
Mydriasis
Parinauds syndrome
Hippus

References
Further reading
"Anisocoria." "Stedmans Medical Dictionary, 27th ed." (2000). ISBN 0-683-40007-X
Victor, Maurice and Allan H. Ropper. "Adams and Victors Principles of Neurology, 7th ed." (2001). ISBN 0-07-067497-3


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