Thus, non secretive adenomas may be either null cell adenomas or a more specific adenoma that, however, remains non-secretive. Any type of pituitary adenocarcinoma listed in the table below may cause compressive symptoms due to local expansion in addition to the systemic effects of secreted hormones listed in the pathology column. Null cell adenomas by definition do not secrete hormones, but they commonly cause compressive effects on the pituitary stalk (stalk effect). This leads to decreased levels of dopamine from the hypothalamus reaching the anterior pituitary gland. Dopamine exerts an inhibitory effect on prolactin secretion. With the absence of this inhibitory effect, prolactin levels increase and are often increased in null cell adenomas. This leads to symptoms of hypogonadism. Pituitary incidentalomas
Pituitary incidentalomas are pituitary tumors that are characterized as an incidental finding. They are often discovered by computed tomography (CT) or magnetic resonance imaging (MRI), performed in the evaluation of unrelated medical conditions such as suspected head trauma, in cancer staging or in the evaluation  of nonspecific symptoms such as dizziness and headache. It is not uncommon for them to be discovered at autopsy. In a meta-analysis, adenomas were found in an average of 16.7% in postmortem studies, with most being  microadenomas (<10mm); macrodenomas accounted for only 0.16% to 0.2% of the decedents.
Erythema elevatum diutinum is a form of vasculitis. : 835 It has been described as a paraneoplastic syndrome. See also
Cutaneous small-vessel vasculitis
List of cutaneous conditions

References


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