Tight clothing, and clothing made of heavy, nonbreathable materials
Deodorants, depilation products, shaving of the affected area – their association with HS is still an ongoing debate among researchers. Drugs, in particular oral contraceptive pills and lithium. Hot and especially humid climates. Predisposing factors
Genetic factors: an autosomal dominant inheritance pattern has been proposed. Endocrine factors: sex hormones, especially an excess of androgens, are thought to be involved, although the apocrine glands are not sensitive to these hormones. Women often have outbreaks before their menstrual period and after pregnancy; HS severity usually decreases during pregnancy and after menopause.Some cases have been found to result from mutations in the NCSTN, PSEN1, or PSENEN genes. The genes produce proteins that are all components of a complex called gamma- (γ-) secretase. This complex cuts apart (cleaves) many different proteins, which is an important step in several chemical signaling pathways. One of these pathways, known as notch signaling, is essential for the normal maturation and division of hair follicle cells and other types of skin cells. Notch signaling is also involved in normal immune system function. Studies suggest that mutations in the NCSTN, PSEN1, or PSENEN gene impair notch signaling in hair follicles. Although little is known about the mechanism, abnormal notch signaling appears to promote the development of nodules and to lead to inflammation in the skin. In addition,  the composition of the intestinal microflora and as a consequence dietary patterns appear to play a role.
Discusses relationship between hymen and concept of virginity. Putting tampon in painlessly Radiology (US - ultrasound) of Hydrocolpos
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