During the formative phase, X-ray images typically reveal calcium deposits with uniform density and a clear margin. In the more painful resorptive phase, deposits instead appear cloudy and with unclear margins. By arthroscopy, formative stage deposits appear crystalline and chalk-like, while resorptive stage deposits appear smooth resembling toothpaste. Ultrasound is also used to locate and assess calcium deposits. In the formative stage, deposits are hyperechoic and arc-shaped; in the resorptive stage deposits are less echogenic and appear fragmented. Treatment
The first line of treatment for calcific tendinitis is typically nonsteroidal anti-inflammatory drugs to relieve pain, rest for the affected joint, and sometimes physical therapy to avoid joint stiffness. For those with severe pain direct injections of steroids to the affected site are often effective for pain relief, but may interfere with reabsorption of the calcium deposit. For those whose pain doesnt improve with medication and rest, the deposit can be dissolved and removed with techniques called "ultrasound-guided needling", "barbotage", and "US-PICT" (for "ultrasound percutaneous injection in calcific tenditis"). In each, ultrasound is used to locate the deposit and guide a needle to the affected site. There saline and lidocaine are injected to dissolve the deposit, then removed to wash it away. Another common treatment is extracorporeal shockwave therapy, where pulses of sound are used to break up the deposit and promote healing. There is little standardization of energy levels, duration, and time interval of treatment; though most studies report positive outcomes with low- to medium-energy waves (below 0.28 mJ/mm2).
Any form of decreased appetite that leads to changes in the body (such as weight loss or muscle loss) that is not done intentionally as part of dieting is clinically significant. Physiology of anorexia
Appetite stimulation and suppression is a complex process involving many different parts of the brain and body by the use of various hormones and signals. Appetite is thought to be stimulated by interplay between peripheral signals to the brain (taste, smell, sight, gut hormones) as well as the balance of neurotransmitters and neuropeptides  in the hypothalamus. Examples of these signals or hormones include neuropeptide Y, leptin, ghrelin, insulin, serotonin, and orexins (also called hypocretins). Anything that causes an imbalance of these signals or hormones can lead to the symptom of anorexia. While it is known that these signals and hormones help control appetite, the complicated mechanisms regarding a pathological increase or decrease in appetite are still being explored. Common causes
Acute radiation syndrome
Addisons disease
Alcoholism
Alcohol withdrawal
Anemia
Anorexia nervosa
Anxiety
Appendicitis
Babesiosis
Benzodiazepine withdrawal
Bipolar disorder
Cancer
Cannabinoid hyperemesis syndrome
Cannabis withdrawal
Celiac disease
Chronic kidney disease
Chronic pain
Common cold
Constipation
COPD
COVID-19
Crohns disease
Dehydration
Dementia
Depression
Ebola
Fatty liver disease
Fever
Food poisoning
Gastroparesis
Hepatitis
HIV/AIDS
Hypercalcemia
Hyperglycemia
Hypervitaminosis D
Hypothyroidism and sometimes hyperthyroidism
Irritable bowel syndrome
Ketoacidosis
Kidney failure
Low blood pressure
Mania
Metabolic disorders, particularly urea cycle disorders
MELAS syndrome
Nausea
Opioid use disorder
Pancreatitis
Pernicious anemia
Psychosis
Schizophrenia
Side effect of drugs
Stimulant use disorder
Stomach flu
Stress
Sickness behavior
Superior mesenteric artery syndrome
Syndrome of inappropriate antidiuretic hormone secretion
Tuberculosis
Thalassemia
Ulcerative colitis
Uremia
Vitamin B12 deficiency
Zinc deficiency
Infection: Anorexia of infection is part of the acute phase response (APR) to infection. The APR can be triggered by lipopolysaccharides and peptidoglycans from bacterial cell walls, bacterial DNA, and double-stranded viral RNA, and viral glycoproteins, which can trigger production of a variety of proinflammatory cytokines.