Four Evangelists – Matthew, Mark, Luke, and John
Four Doctors of Western Church – Saint Gregory the Great, Saint Ambrose, Saint Augustine, and Saint Jerome
Four Doctors of Eastern Church – Saint John Chrysostom, Saint Basil the Great, and Gregory of Nazianzus and Saint Athanasius
Four Galilean moons of Jupiter – Io, Europa, Ganymede, and Callisto
The Gang of Four was a Chinese communist political faction. The Fantastic Four: Mr. Fantastic, The Invisible Woman, The Human Torch, The Thing. The Teenage Mutant Ninja Turtles: Leonardo, Michelangelo, Donatello, Raphael
The Beatles were also known as the "Fab Four": John Lennon, Paul McCartney, George Harrison, Ringo Starr. Gang of Four is a British post-punk rock band formed in the late 1970s. Four rivers in the Garden of Eden (Genesis 2:10–14): Pishon (perhaps the Jaxartes or Syr Darya), Gihon (perhaps the Oxus or Amu Darya), Hiddekel (Tigris), and Prat (Euphrates). There are also four years in a single Olympiad (duration between the Olympic Games). Many major international sports competitions follow this cycle, among them the FIFA World Cup and its womens version, the FIBA World Championships for men and women, and the Rugby World Cup. There are four limbs on the human body. Four Houses of Hogwarts in the Harry Potter series: Gryffindor, Hufflepuff, Ravenclaw, Slytherin. Four known continents of the world in the A Song of Ice and Fire series: Westeros, Essos, Sothoryos, Ulthos. Each Grand Prix in Nintendos Mario Kart series is divided into four cups and each cup is divided into four courses.
Holistically, there are four elementary arithmetic operations in mathematics: addition (+), subtraction (−), multiplication (×), and division (÷); and four basic number systems, the real numbers 
  
    
      
        
          R
        
      
    
    {\displaystyle \mathbb {R} }
  , rational numbers 
  
    
      
        
          Q
        
      
    
    {\displaystyle \mathbb {Q} }
  , integers 
  
    
      
        
          Z
        
      
    
    {\displaystyle \mathbb {Z} }
  , and natural numbers 
  
    
      
        
          N
        
      
    
    {\displaystyle \mathbb {N} }
  .