With decreased sleep, a person is increasing Aβ production and decreasing Aβ clearance, resulting in Aβ accumulation. Receiving adequate sleep (approximately 7–8 hours) every night has become a potential lifestyle intervention to prevent the development of AD.Stress is a risk factor for the development of Alzheimers. The mechanism by which stress predisposes someone to development of Alzheimers is unclear, but it is suggested that lifetime stressors may affect a persons epigenome, leading to an overexpression or under expression of specific genes. Although the relationship of stress and Alzheimers is unclear, strategies to reduce stress and relax the mind may be helpful strategies in preventing the progression or Alzheimers disease. Meditation, for instance,  is a helpful lifestyle change to support cognition and well-being, though further research is needed to assess long-term effects. Management
There is no cure for Alzheimers disease; available treatments offer relatively small symptomatic benefits but remain palliative in nature. Treatments can be divided into pharmaceutical, psychosocial, and caregiving. Pharmaceutical
Medications used to treat the cognitive problems of Alzheimers disease include: four acetylcholinesterase inhibitors (tacrine, rivastigmine, galantamine, and donepezil) and memantine, an NMDA receptor antagonist. The acetylcholinesterase inhibitors are intended for those with mild to severe Alzheimers, whereas memantine is intended for those with moderate or severe Alzheimers disease. The benefit from their use is small.Reduction in the activity of the cholinergic neurons is a well-known feature of Alzheimers disease.
Parliamentary Commissioner for the Environment, New Zealand government agency

Political parties
Spain
PCE, Communist Party of Spain or "Partido Comunista de España"
PCE(i), Communist Party of Spain (International)(1975) or Partido Comunista de España(Internacional)
PCE(m-l), Communist Party of Spain (Marxist–Leninist) or Partido Comunista de España (Marxista-Leninista)
PCE(ML), Communist Party of Spain (Marxist–Leninist) (historical) or Partido Comunista de España (Marxista-Leninista)
PCE(M-R), Workers Party of Spain–Communist Unity or Partido de los Trabajadores de España–Unidad Comunista
PCE(R), Communist Party of Spain (Reconstituted) or Partido Comunista de España (Reconstituido)

Other countries
Parti Communautaire Européen, a political party in Belgium
Partido Comunista del Ecuador, the Communist Party of Ecuador

Other
ISO 639:pce or Palaung language, spoken in Burma and neighboring countries
Passenger car equivalent, a measure of traffic flow
PCE-842-class patrol craft, U.S. Navy patrol craft escorts, many of which were transferred to the Philippine Navy
Power cost equalization, a state subsidy in Alaska
Parduice