Jody Roberts, a reporter for the Tacoma News Tribune, disappeared in 1985, only to be found 12 years later in Sitka, Alaska, living under the name of "Jane Dee Williams". While there were some initial suspicions that she had been faking amnesia, some experts have come to believe that she genuinely experienced a protracted fugue state. David Fitzpatrick, who had dissociative fugue disorder, was profiled in the UK on Fives television series Extraordinary People. He entered a fugue state on December 4, 2005, and was working on regaining his entire lifes memories at the time of his appearance in his episode of the documentary series. Hannah Upp, a teacher originally from Salem, Oregon, was given a diagnosis of dissociative fugue after she had disappeared from her New York home in August 2008 and was rescued from the New York Harbor 20 days later. News coverage at the time focused on her refusal to speak to detectives right after she was found  and the fact that she was seen checking her email at Apple Stores while she was missing. This coverage has since led to criticism of the often "condemning and discrediting" attitude toward dissociative conditions. On September 3, 2013, she went into another fugue, disappearing from her new job as a teachers assistant  at Crossway Community Montessori in Kensington, Maryland. She was found unharmed September 5, 2013, in Wheaton, Maryland.
The status of the patients renal function and hepatic function must also be taken into consideration to avoid an accumulation that may lead to a fatal drug overdose. Ofloxacin is eliminated primarily by renal excretion. However, the drug is also metabolized and partially cleared through the liver. Modification of the dosage is required using the table found within the package insert for those with impaired liver or kidney function (particularly for patients with severe renal dysfunction). However, since the drug is known to be substantially excreted by the kidneys, the risk of toxic reactions to this drug may be greater in patients with impaired renal function. The duration of treatment depends upon the severity of infection and the usual duration is 7 to 14 days. Antibiotic use and bacterial resistance
Resistance to ofloxacin and other fluoroquinolones may evolve rapidly, even during a course of treatment. Numerous pathogens, including Staphylococcus aureus, enterococci, and Streptococcus pyogenes now exhibit resistance worldwide.Floxacin and other fluoroquinolones had become the most commonly prescribed class of antibiotics to adults in 2002. Nearly half (42%) of these prescriptions were for conditions not approved by the U.S. Food and Drug Administration (FDA), such as acute bronchitis, otitis media, and acute upper respiratory tract infection, according to a study that was supported in part by the Agency for Healthcare Research and Quality. Additionally they are commonly prescribed for medical conditions that are not even bacterial to begin with, such as viral infections, or those to which no proven benefit exists. References
External links
"Ofloxacin". Drug Information Portal.