The points to look at are: eye position, eye symmetry and twisting of the nasal tip.The implications of the deformities that are seen are extensively discussed under phenotype. Syndromal craniosynostosis presents with a skull deformity as well as deformities affecting other parts of the body. Clinical examination should in any case include evaluation of the neck, spine, digits and toes. Medical imaging
Radiographic analysis by performing a computed axial tomographic scan is the gold standard for diagnosing craniosynostosis.Plain radiography of the skull may be sufficient for diagnosing a single suture craniosynostosis and should therefore be performed, but the diagnostic value is outweighed by that of the CT-scan. Not only can the sutures be identified more accurately, thus objectively demonstrating a fused suture, but also evaluation of the brain for structural abnormalities and excluding other causes of asymmetric growth are possible at the same time. In addition to this, CT-scanning can visualize the extent of skull deformity, thereby enabling the surgeon to start planning surgical reconstruction. Classification
There are several ways to classify craniosynostosis. For example, one can consider the number of closed sutures. If only one of the four sutures is prematurely closed (single suture craniosynostosis), the craniosynostosis is referred to as simple (or isolated). Whereas when two or more sutures are no longer open, the craniosynostosis is complex. A second classification scheme gives a clinical description of the resulting shape of the skull. This will be further discussed under phenotype. A third classification involves the presence or absence of an identified craniofacial syndrome.
Treatment
The primary goal of surgical intervention is to allow normal cranial vault development to occur. This can be achieved by excision of the prematurely fused suture and correction of the associated skull deformities. If the synostosis goes uncorrected, the deformity will progressively worsen not only threatening the aesthetic aspect, but also the functional aspect. This is especially prevalent with asymmetric conditions, such as unilateral coronal synostosis, with compromised function of the eyes and the jaw. In addition, signs of compromised neurodevelopment have been seen amongst all the synostoses, although this may also be caused by primary maldevelopment of the brain and can thus not be prevented by surgical intervention.There are a few basic elements involved in surgical intervention which is aimed at normalization of the cranial vault:

Surgery for craniosynostosis is often associated with significant perioperative hemorrhage so multiple strategies are often used to minimize blood loss. One such method involves the injection of vasoconstrictive agents (i.e. epinephrine) seven to ten minutes before scalp incision. Additionally, the initiation of surgery should be delayed until blood products are physically present in the operating room. Another general agreement is the avoidance of the use of titanium plates in the fixation of the skull. One potential complication following this procedure involves the gradual movement of the titanium plates towards the brain, induced by resorption of the innermost bone layer of the skull with deposition of new bone on the outermost layer, thereby integrating the titanium plates.