Some symptoms that are more closely associated with liver disease include yellow skin (also called jaundice), abdominal swelling due to fluid in the abdominal cavity, easy bruising from blood clotting abnormalities, loss of appetite, unintentional weight loss, abdominal pain, nausea, vomiting, or feeling tired. Risk factors
Since HCC mostly occurs in people with cirrhosis of the liver, risk factors generally include factors which cause chronic liver disease that may lead to cirrhosis. Still, certain risk factors are more highly associated with HCC than others. For example, while heavy alcohol consumption is estimated to cause 60–70% of cirrhosis, the vast majority of HCC occurs in cirrhosis attributed to viral hepatitis (although there may be overlap). Recognized risk factors include:

Chronic viral hepatitis (estimated cause of 80% cases globally)
Chronic hepatitis B (about 50% cases)
Chronic hepatitis C (about  25% cases)
Toxins:
Alcohol use disorder: the most common cause of cirrhosis
Aflatoxin
Iron overload state (hemochromatosis)
Pyrrolizidine alkaloids
Metabolic:
Nonalcoholic steatohepatitis: up to 20% progress to cirrhosis 
Nonalcoholic fatty liver disease
Type 2 diabetes (probably aided by obesity)
Congenital disorders:
Alpha 1-antitrypsin deficiency
Wilsons disease (controversial; while some theorise the risk increases, case studies are rare and suggest the opposite where Wilsons disease actually may confer protection)
Hemophilia, although statistically associated with higher risk of HCC, this is due to coincident chronic viral hepatitis infection related to repeated blood transfusions over lifetime.The significance of these risk factors varies globally. In regions where hepatitis B infection is endemic, such as southeast China, hepatitis B is the predominant cause.
Activity may refer to:

Action (philosophy), in general
Human activity: human behavior, in sociology behavior may refer to all basic human actions, economics may study human economic activities and along with cybernetics and psychology may study their modulation
Recreation, or activities of leisure
The Aristotelian concept of energeia, Latinized as actus
Activity (UML), a major task in Unified Modeling Language
Activity, the rate of catalytic activity, such as enzyme activity (enzyme assay), in physical chemistry and enzymology
Thermodynamic activity, the effective concentration of a solute for the purposes of  mass action
Activity (project management)
Activity, the number of radioactive decays per second
Activity (software engineering)
Activity (soil mechanics)
HMS Activity (D94), an aircraft carrier of the Royal Navy
"Activity", a song by Way Out West from Intensify
Cultural activities, activities referred to culture. See also
Activity theory, a learning theory in education
Social activity (disambiguation), several concepts in the social sciences
Activiti (software), an open source Business Process Management platform
Active (disambiguation)