The results of the study suggest that people with iRBD are more likely to report having a first-degree relative with the same sleep disorder than people of the same age and sex that do not have the disorder. More research needs to be conducted to further understand the hereditary nature of sleep disorders. A population susceptible to the development of sleep disorders includes people who have experienced a traumatic brain injury (TBI). Because many researchers have focused on this issue, a systematic review was conducted to synthesize their findings. The results indicate that individuals who experienced a TBI are most disproportionately at risk for developing narcolepsy, obstructive sleep apnea, excessive daytime sleepiness, and insomnia. The studys complete findings can be found in the table below:

Sleep disorders and Neurodegenerative Diseases
Neurodegenerative diseases have often been associated with sleep disorders, mainly when they are characterized by abnormal accumulation of alpha-synuclein, such as multiple system atrophy (MSA), Parkinsons disease (PD) and Lewy body disease (LBD). For instance, people diagnosed with PD have often presented different kinds of sleep concerns, commonly in regard to insomnia (around 70% of the PD population), hypersomnia (more than 50% of the PD population), and REM sleep behavior disorder (RBD) - that may affect around 40% of the PD population and it is associated with increased motor symptoms.
A placental site nodule (PSN) is benign remnant from a previous pregnancy. Presentation
They are typically asymptomatic and found incidentally. Pathology
PSNs are intermediate trophoblastic remnants. Diagnosis
PSN are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage. Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site. Prognosis
PSN are benign. Once removed, they do not require any treatment and do not recur. See also
Gestational trophoblastic disease
Placental site trophoblastic tumour

References


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