On the other hand, soft tissue and medullary cavity is better imaged by MRI scan.Most times, the early signs of osteosarcoma are caught on X-rays taken during routine dental check-ups. Osteosarcoma frequently develops in the mandible (lower jaw); accordingly, dentists are trained to look for signs that may suggest osteosarcoma. Even though radiographic findings for this cancer vary greatly, one usually sees a symmetrical widening of the periodontal ligament space. A dentist who has reason to suspect osteosarcoma or another underlying disorder would then refer the patient to an Oral & Maxillofacial surgeon for biopsy. A biopsy of suspected osteosarcoma outside of the facial region should be performed by a qualified orthopedic oncologist. The American Cancer Society states: "Probably in no other cancer is it as important to perform this procedure properly. An improperly performed biopsy may make it difficult to save the affected limb from amputation." It may also metastasise to the lungs, mainly appearing on the chest X-ray as solitary or multiple round nodules most common at the lower regions. Variants
Conventional: osteoblastic, chondroblastic, fibroblastic OS
Telangiectatic OS
Small cell OS
Low-grade central OS
Periosteal OS
Paraosteal OS
Secondary OS
High-grade surface OS
Extraskeletal OS

Treatment
A complete radical, surgical, en bloc resection of the cancer, is the treatment of choice in osteosarcoma.
Alexis Littre (17 July 1654 – 3 February 1726) was a French physician and anatomist born in Cordes (currently Cordes-Tolosannes in the department of Tarn-et-Garonne). Biography
Littre studied medicine in Montpellier and Paris, receiving his doctorate in 1691. In 1699 he became a member of the Académie des Sciences. In Paris, he taught anatomy and was the author of numerous medical publications. He was the first to give a description of a hernial protrusion of an intestinal diverticulum. This condition is now referred to as "Littres hernia".He also described the mucous urethral glands of the male urethra. These structures were to become known as "Littres glands", and their inflammation is sometimes called "littreitis".In his 1710 treatise Diverses observations anatomiques, Littre was the first to suggest the possibility of performing a lumbar colostomy for an obstruction of the colon.Jean Louis Petit was one of his students. So was Jacques-Bénigne Winslow in 1707. He died in Paris. References
Alexis de Littre @ Who Named It

Notes
External links
Online articles by Littré 10 articles (2012-05-15) on the site of the Académie des sciences. Cotlar, Alvin M. (January 2002). "Historical landmarks in operations on the colon—surgeons courageous". Current Surgery. Elsevier. 59 (1): 91–95. doi:10.1016/s0149-7944(01)00606-7. ISSN 0149-7944. PMID 16093113. Bernard Le Bovier de Fontenelle, Éloge de Monsieur Littré, p. 129, at Google Books, 1754, p. 129 (Eulogy)