Clinical trial number NCT02817828 for "E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - EU/Russia Study" at ClinicalTrials.gov
Clinical trial number NCT02817841 for "E4 FREEDOM (Female Response Concerning Efficacy and Safety of Estetrol/Drospirenone as Oral Contraceptive in a Multicentric Study) - United States/Canada Study" at ClinicalTrials.gov
Surgery works by changing the shape of the cornea. Far-sightedness primarily affects young children, with rates of 8% at 6 years and 1% at 15 years. It then becomes more common again after the age of 40, known as presbyopia, affecting about half of people. Best treatment option to correct hypermetropia due to aphakia is IOL implantation.Other common types of refractive errors are near-sightedness, astigmatism, and presbyopia. Signs and symptoms
In young patients, mild hypermetropia may not produce any symptoms. The signs and symptoms of far-sightedness include blurry vision, frontal or fronto temporal headaches, eye strain, tiredness of eyes etc. The common symptom is eye strain. Difficulty seeing with both eyes (binocular vision) may occur, as well as difficulty with depth perception. The asthenopic symptoms and near blur are usually seen after close work, especially in the evening or night. Complications
Far-sightedness can have rare complications such as strabismus and amblyopia. At a young age, severe far-sightedness can cause the child to have double vision as a result of "over-focusing".Hypermetropic patients with short axial length are at higher risk of developing primary angle closure glaucoma, so, routine gonioscopy and glaucoma evaluation is recommended for all hypermetropic adults. Causes
Simple hypermetropia, the most common form of hypermetropia, is caused by normal biological variations in the development of eyeball. Aetiologically, causes of hypermetropia can be classified as:

Axial: Axial hypermetropia occur when the axial length of eyeball is too short. About 1 mm decrease in axial length cause 3 diopters of hypermetropia. One condition that cause axial hypermetropia is nanophthalmos.