It was considered acceptable to operate on them without anesthetic because, Sims claimed, African-American women have a naturally higher pain tolerance.The healing process of the VVF procedure is still arduous. To have a successful recovery from the surgery, it must be successful on the first attempt. Dr. J. Marion Sims operations on African-American enslaved women showcase the dangerous nature of the procedure. There still have not been clear instructions on how to properly recover from the procedure other than taking prescribed antibiotics. See also
Colposcopy
Double dye test
Rectovaginal fistula
Urinary incontinence

References


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Famotidine, sold under the brand name Pepcid among others, is a histamine H2 receptor antagonist medication that decreases stomach acid production. It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is taken by mouth or by injection into a vein. It begins working within an hour.Common side effects include headache, intestinal upset, and dizziness. Serious side effects may include pneumonia and seizures. Use in pregnancy appears safe but has not been well studied while use during breastfeeding is not recommended.Famotidine was patented in 1979 and came into medical use in 1985. It is available as a generic medication. In 2019, it was the 104th most commonly prescribed medication in the United States, with more than 6 million prescriptions. Medical uses
Relief of heartburn, acid indigestion, and sour stomach
Treatment for gastric and duodenal ulcers
Treatment for pathologic gastrointestinal hypersecretory conditions such as Zollinger–Ellison syndrome and multiple endocrine adenomas
Treatment for gastroesophageal reflux disease (GERD)
Treatment for esophagitis
Part of a multidrug regimen for Helicobacter pylori eradication, although omeprazole may be somewhat more effective. Prevention of NSAID-induced peptic ulcers. Given to surgery patients before operations to reduce the risk of aspiration pneumonitis. Pharmacokinetics
Famotidine has a delayed onset of action, beginning after 90 minutes. However, famotidine has a duration of effect of at least 540 minutes (9.0 h). At its peak effect, 210 minutes (3.5 h) after administration, famotidine reduces acid secretion by 7.3 mmol per 30 minutes.