Kabuki syndrome (also previously known as Kabuki-makeup syndrome (KMS) or Niikawa–Kuroki syndrome) is a congenital disorder of genetic origin. It affects multiple parts of the body, with varying symptoms and severity, although the most common is the characteristic facial appearance.It is quite rare, affecting roughly one in 32,000 births. It was first identified and described in 1981 by two Japanese groups, led by scientists Norio Niikawa and Yoshikazu Kuroki. It is named Kabuki syndrome because of the facial resemblance of affected individuals to stage makeup used in kabuki, a Japanese traditional theatrical form. Signs and symptoms
Specific symptoms for Kabuki syndrome vary, with large differences between affected individuals. Most people with Kabuki syndrome have distinctive facial features that include arched eyebrows, long eyelashes, elongated eyelids with lower lids that turn out, prominent ears, a flat tip of the nose and a downward slant to the mouth.Overlapping phenotypic features for patients between KDM6A and KDM6B variations include prominent ears, abnormal dentition, congenital heart disease, feeding difficulties, cryptorchidism, joint hypermobility, developmental delay, hypotonia, and behavioral difficulties. Other common symptoms are skeletal abnormalities, short stature, heart defects, feeding difficulties and a failure to thrive, vision and hearing difficulties, weak muscle tone (hypotonia), small head size (microcephaly), and frequent infections.Mild to moderate intellectual disability and mild to severe developmental delay are often associated with Kabuki syndrome. Infants and young children often experience difficulties relating to hypotonia, feeding issues/failure to thrive, infections, surgical repair of heart and palate defects and developmental delays.Young children with Kabuki syndrome benefit from early intervention services.
Amok may refer to:

Running amok, the act of behaving disruptively or uncontrollably. Film
Amok (1934 film), a French film
Amok (1944 film), a Mexican romantic drama
Amok (1983 film), a Moroccan drama

Literature
Amok (comics), an Italian comic book series
Amok (novella), by Stefan Zweig, 1922
Amok, a 1974 novel by Harry Thürk
Amok, a 2003 novel by Krystian Bala

Music
Amok (The Late B.P. Helium album), 2004
Amok (Sentenced album), 1995
Amok (Atoms for Peace album), 2013

Other uses
Steamed curry (Khmer: អាម៉ុក, amŏk), name in Cambodia for a curry steam-cooked in banana leaves
Fish amok, a Cambodian steamed fish curry
Amok (video game), a 1996 video game for the Sega Saturn
Mok language, also known as Amok
Amok (publisher), now Frémok, a Franco-Belgian comics publishing house
Amok Press, a defunct American book imprint

See also
All pages with titles beginning with Amok
All pages with titles containing Amok
"Amok Time", a 1967 episode of Star Trek: The Original Series
Amuck!, a 1972 Italian giallo film
AMOC (disambiguation)