Some research examines the differences and comorbidity when looking into birth-related posttraumatic stress disorder, or postpartum posttraumatic stress disorder, and postpartum depression. In the recent research, similarities and differences in symptoms have been identified when it comes to postpartum posttraumatic stress disorder and postpartum depression. Although both diagnoses have overlap in their diagnostic criteria, some of the criteria specific to postpartum depression include intense hopelessness and sadness, excessive worry or anxiety, intrusive thoughts of harm to oneself or harm to the baby, feelings of guilt or thoughts of worthlessness, and a change in appetite which could result in under-eating or overeating. On the other hand, diagnostic criteria specific to postpartum posttraumatic stress disorder includes being easily startled, recurring nightmares and flashbacks, avoiding the baby or anything that reminds one of birth, aggression, irritability, and panic attacks. Although these are the symptoms that often help differentiate between postpartum posttraumatic stress disorder and postpartum depression, it is important to note that some of these symptoms can cross over to the other diagnosis (e.g., someone meeting the diagnostic criteria of postpartum depression may also present with panic attacks, or someone meeting the diagnostic criteria for postpartum posttraumatic stress disorder may experience depressive episodes, etc.). Another crucial element in diagnosing postpartum posttraumatic stress disorder following childbirth is when there is a real or perceived trauma before, during, or following childbirth, which is not always required when it comes to diagnosing someone with postpartum depression.
Targeted treatments, such as immunotherapy, hormonal therapy and kinase inhibitors, are being evaluated for tumors that do not respond to chemotherapy. Prognosis
The 1997 International Germ Cell Consensus Classification is a tool for estimating the risk of relapse after treatment of malignant germ-cell tumor. A small study of ovarian tumors in girls reports a correlation between cystic and benign tumors, and conversely, solid and malignant tumors. Because the cystic extent of a tumor can be estimated by ultrasound, MRI, or CT scan before surgery, this permits selection of the most appropriate surgical plan to minimize risk of spillage of a malignant tumor.Access to appropriate treatment has a large effect on outcome. A 1993 study of outcomes in Scotland found that for 454 men with nonseminomatous (nongerminomatous) GCTs diagnosed between 1975 and 1989, five-year survival increased over time and with earlier diagnosis. Adjusting for these and other factors, survival was 60% higher for men treated in a cancer unit that treated the majority of these men,  though the unit treated more men with the worst prognosis.Choriocarcinoma of the testicles has the worst prognosis of all germ-cell cancers. See also
Embryonic stem cells
Cancer research

References
External links

humpath #2658 (Pathology images)
Childhood Extracranial Germ Cell Tumors
Extragonadal Germ Cell Tumors
Ovarian Germ Cell Tumors
Packer RJ, Cohen BH, Cooney K, Coney K (2000). "Intracranial germ cell tumors". The Oncologist. 5 (4): 312–320. doi:10.1634/theoncologist.2000-0312. PMID 10964999. Cancer.Net: Germ Cell Tumor