Notable cases
In 1989, The Golden Girls (1985–1992) featured chronic fatigue syndrome in a two-episode arc, "Sick and Tired: Part 1" and "Part 2", in which protagonist Dorothy Zbornak, portrayed by Bea Arthur, after a lengthy battle with her doctors in an effort to find a diagnosis for her symptoms, is finally diagnosed with CFS. American author Ann Bannon had CFS. Laura Hillenbrand, author of the popular book Seabiscuit, has struggled with CFS since age 19. Research
The different case definitions used to research the illness influence the types of patients selected for studies, and research also suggests subtypes of patients may exist within a heterogeneous population. In one of the definitions, symptoms are accepted that may suggest a psychiatric disorder, while others specifically exclude primary psychiatric disorders. The lack of a single, unifying case definition was criticized in the Institute of Medicines 2015 report for "creating an unclear picture of the symptoms and signs of the disorder" and "complicating comparisons of the results" (study results). : 72 More robust diagnostic methods are being investigated with the aim of identifying unique biomarkers that may be used in clinical testing. In 2019, two different papers were published proposing blood-based biomarkers for CFS. One found that blood cells of CFS patients could be distinguished from healthy controls by their response to hyperosmotic stress. Another found that the red blood cells of CFS patients were stiffer, and thus less able to deform in order to pass through capilliaries. See also
Long COVID
Unrest (2017 film)

References
External links

"CDC – Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)".
Olmesartan/amlodipine/hydrochlorothiazide, sold under the brand name Tribenzor, is a fixed-dose combination medication used to treat high blood pressure. It contains olmesartan medoxomil, an angiotensin-2 receptor antagonist (ARB or A2A), amlodipine, a calcium channel blocker, and hydrochlorothiazide, a diuretic. It is taken by mouth. References
External links
"Amlodipine mixture with hydrochlorothiazide and olmesartan medoxomil". Drug Information Portal. U.S. National Library of Medicine.