Trandolapril has a half-life of about 6 hours, and trandolaprilat has a half life of about 10 h. Trandolaprilat has about eight times the activity of its parent drug. About one-third of trandolapril and its metabolites are excreted in the urine, and about two-thirds of trandolapril and its metabolites are excreted in the feces. Serum protein binding of trandolapril is about 80%. Mode of action
Trandolapril acts by competitive inhibition of angiotensin converting enzyme (ACE), a key enzyme in the renin–angiotensin system which plays an important role in regulating blood pressure. References
External links
Trandolapril Information - rxlist.com (Rxlist.com, The Internet Drug Index)
Unless the organizations rules require it, a summary of the discussions in a meeting is neither necessary nor appropriate.The minutes of certain groups, such as a corporate board of directors, must be kept on file and are important legal documents. Minutes from board meetings are kept separately from minutes of general membership meetings within the same organization. Also, minutes of executive sessions may be kept separately. Committees are not required to keep formal minutes although less formal notes may be taken. For committees, their formal records are the reports submitted to their parent body. Format
The format of the minutes can vary depending on the standards established by an organization, although there are general guidelines. Roberts Rules of Order contains a sample set of minutes.Generally, minutes begin with the name of the body holding the meeting (e.g., a board) and may also include the place, date, list of people present, and the time that the chair called the meeting to order.Since the primary function of minutes is to record the decisions made, all official decisions must be included. If a formal motion is proposed and seconded, then (regardless whether it passes) this is recorded. The voting tally may also be included. The part of the minutes dealing with a routine motion might note merely that a particular motion was "moved by Ann and passed". It is not strictly necessary to include the name of the person who seconds a motion.