Six or more spots of at least 5mm in diameter in pre-pubertal children and at least 15mm in post-pubertal individuals is one of the major diagnostic criteria for NF1. Prognosis
Café au lait spots are usually present at birth, permanent, and may grow in size or increase in number over time.Cafe au lait spots are themselves benign and do not cause any illness or problems. However, they may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome.The size and shape of the spots can vary in terms of description. In Neurofibromatosis Type 1, the spots tend to be described as ovoid, with smooth borders. In other disorders, the spots can be less ovoid, with jagged borders. In Neurofibromatosis Type 1, the spots tend to resemble the "coast of California," rather than the "coast of Maine," meaning the edges are smoother and more linear. Treatment
Café au lait spots can be removed with lasers. Results are variable as the spots are often not completely removed or can come back after treatment. Often, a test spot is treated first to help predict the likelihood of treatment success. See also
Birthmark
Nevus
List of cutaneous conditions
List of conditions associated with café au lait macules

References
External links

eMedicine
This procedure greatly decreases the rate of miscarriage for women with this anomaly. Prevalence
The prevalence of uterine malformation is estimated to be 6.7% in the general population, slightly higher (7.3%) in the infertility population, and significantly higher in a population of women with a history of recurrent miscarriages (16%). See also
Uterus didelphys
Uterus § Other animals – where some malformations in humans are "normal"

References
External links
BBC NEWS - Triplets for woman with two wombs