For women with Lynch syndrome, a yearly CA-125 blood test can be used to screen for ovarian cancer, however there is limited data on the efficacy of this test in reducing mortality.Other cancers
There are also strategies for detecting other cancers early or reducing the chances of developing them that people with Lynch syndrome can discuss with their doctor, however their effectiveness is not clear. These options include:

Upper endoscopies to detect stomach and small bowel cancer every 3–5 years, starting at age 30 at the earliest (preferably in a research setting)
Annual urinalysis to detect bladder cancer, starting at age 30 at the earliest (preferably in a research setting)
Annual physical and neurological exams to detect cancer in the central nervous system (brain or spinal cord), starting at age 25 at the earliest

Amsterdam criteria
The following are the Amsterdam criteria in identifying high-risk candidates for molecular genetic testing:Amsterdam I Criteria (all bullet points must be fulfilled): The Amsterdam I criteria were published in 1990; however, were felt to be insufficiently sensitive.
Unfortunately, having chronic erythrocyte transfusions, it can be extremely harmful to the body and can cause severe complications.To help with dry eye symptoms and visual function, topical lubrication can be used. A more invasive way to help treat Gunthers disease would be to have surgery. There have been numerous studies that have stated that bone marrow transplantation is successful. This is a recently new development for Gunthers disease so the long-term effects are still unresourced. If a patient has a life-threatening infectious complication then bone marrow transplantation is no longer relevant for them. There are also reports that stem cell transplantation is successful in a limited number of participants

Eponym
The disorder is named after the German physician who discovered it, Hans Günther (1884-1956). See also
Porphyria cutanea tarda
List of cutaneous conditions
List of dental abnormalities associated with cutaneous conditions

References
External links
Porphyria, congenital erythropoietic at NIHs Office of Rare Diseases