IGF-1 is responsible for most of the symptoms of acromegaly, and the normalization of its levels can control the symptoms.Long-term treatment studies with pegvisomant as a monotherapy have shown it to be safe, and effective. Research
Some studies show the potential of using pegvisomant as an anti-tumor treatment for certain types of cancers. References
External links
"Pegvisomant". Drug Information Portal. U.S. National Library of Medicine.
Brain scans of both sexes have shown that the pleasure centers of a mans brain show more intense activity than in women during orgasm.Male and female brains demonstrate similar changes during orgasm, with brain activity scans showing a temporary decrease in the metabolic activity of large parts of the cerebral cortex with normal or increased metabolic activity in the limbic areas of the brain.EEG tracings from volunteers during orgasm were first obtained by Mosovich and Tallaferro in 1954. These research workers recorded EEG changes resembling petit mal or the clonic phase of a grand mal seizure. Further studies in this direction were carried out by Sem-Jacobsen (1968), Heath (1972), Cohen et al. (1976), and others. Sarrel et al. reported a similar observation in 1977. These reports continue to be cited. Unlike them, Craber et al. (1985) failed to find any distinctive EEG changes in four men during masturbation and ejaculation; the authors concluded that the case for the existence of EEG changes specifically related to sexual arousal and orgasm remained unproven. So disagreement arises as to whether the experiment conducted by Mosovich & Tallaferro casts a new light on the nature of orgasm. In some recent studies, authors tend to adopt the opposite point of view that there are no remarkable EEG changes during ejaculation in humans. Health
General
Orgasm, and sexual activity as a whole, are physical activities that can require exertion of many major bodily systems.