A sequence of events may also be used to help describe processes in science, technology, and medicine. A sequence of events may be focused on past events (e.g., stories, history, chronology), on future events that must be in a predetermined order (e.g., plans, schedules, procedures, timetables), or focused on the observation of past events with the expectation that the events will occur in the future (e.g., processes, projections). The use of a sequence of events occurs in fields as diverse as machines (cam timer), documentaries (Seconds From Disaster), law (choice of law), finance (directional-change intrinsic time), computer simulation (discrete event simulation), and electric power transmission
(sequence of events recorder). A specific example of a sequence of events is the timeline of the Fukushima Daiichi nuclear disaster. See also
List of UTC timing centers
Time metrology

Organizations
Antiquarian Horological Society – AHS (United Kingdom)
Chronometrophilia (Switzerland)
Deutsche Gesellschaft für Chronometrie – DGC (Germany)
National Association of Watch and Clock Collectors – NAWCC (United States)

References
Further reading
External links

Different systems of measuring time
Time on In Our Time at the BBC
Time in the Internet Encyclopedia of Philosophy, by Bradley Dowden. Le Poidevin, Robin (Winter 2004). "The Experience and Perception of Time". In Edward N. Zalta (ed.). The Stanford Encyclopedia of Philosophy. Retrieved 9 April 2011.
This occurs by blocking the nucleoside transporter (ENT1) through which adenosine enters erythrocyte and endothelial cells.According to Association of Anaesthetists of Great Britain and Ireland 2016 guidelines, dipyridamole is considered to not cause risk of bleeding when receiving neuroaxial anaesthesia and deep nerve blocks. It does not therefore require cessation prior to anaesthesia with these techniques, and can continue to be taken with nerve block catheters in place. Overdose
Dipyridamole overdose can be treated with aminophylline: 6  or caffeine which reverses its dilating effect on the blood vessels. Symptomatic treatment is recommended, possibly including a vasopressor drug. Gastric lavage should be considered. Since dipyridamole is highly protein bound, dialysis is not likely to be of benefit. Mechanisms of action
Dipyridamole has two known effects, acting via different mechanisms of action:

Dipyridamole inhibits the phosphodiesterase enzymes that normally break down cAMP (increasing cellular cAMP levels and blocking the platelet aggregation, response to ADP) and/or cGMP. Dipyridamole inhibits the cellular reuptake of adenosine into platelets, red blood cells, and endothelial cells, leading to increased extracellular concentrations of adenosine. Experimental studies
Dipyridamole is currently undergoing repurposing for treatment of ocular surface disorders. These include pterygium and dry eye disease. The first report of topical dipyridamoles benefit in treating pterygium was published in 2014. A subsequent report of outcomes in 25 patients using topical dipyridamole was presented in 2016. See also
Acetylsalicylic acid/dipyridamole
Cilostazol


== References ==