Elevation of the nail bed can occur. In rare cases, the tumors may present in other body areas, such as the gastric antrum or glans penis. Treatment is essentially the same.Malignant glomus tumors, or glomangiosarcomas, are extremely rare and usually represent a locally infiltrative malignancy. However, metastases do occur and are usually fatal. Diagnosis
Cancerous glomus tumors are exceedingly rare. Criteria for the diagnosis of malignancy in glomus tumors are:
Tumor size of more than 2 centimeters and subfascial or visceral location. Atypical mitotic figures. Marked nuclear atypia and any level of mitotic activity. Pericytes of ZimmermanCancerous glomus tumors have been subdivided into three categories based on their histologic appearance: locally infiltrative glomus tumors (LIGT), glomangiosarcomas arising in benign glomus tumors (GABG), and glomangiosarcomas arising de novo (GADN).A few cases of cancerous glomus tumors have been reported; however, they are usually only locally invasive, and metastases are exceedingly rare. There is one report of widespread metastases of a malignant glomus tumor involving the skin, lungs, jejunum, liver, spleen, and lymph nodes. Another report of a malignant glomus tumor (glomangiosarcoma) with metastases from the skin. A malignant glomus tumor one arose from the kidneys. Differential
The probable misdiagnosis of many of these lesions as hemangiomas or venous malformations also makes an accurate assessment of incidence difficult. Treatment
Surgical excision is the preferred treatment for benign glomus tumors. Epidemiology
The exact rate of glomus tumors is unknown. The multiple variant is rare, accounting for less than 10% of all cases.
Sex
Solitary glomus tumors, particularly subungual lesions, are more common in females than in males. Multiple lesions are slightly more common in males. Age
Solitary glomus tumors are more frequent in adults than in others. Multiple glomus tumors develop 11–15 years earlier than single lesions; about one third of the cases of multiple tumors occur in those younger than 20 years. Congenital glomus tumors are rare; they are plaguelike in appearance and are considered a variant of multiple glomus tumors. See also
Coccygeal glomus
List of cutaneous conditions
Myopericytoma

References
External links

synd/1584 at Who Named It? 00314 at CHORUS