Prior to beginning his comedy career, Bob Saget made a documentary short called "Through Adams Eyes" documenting his young nephews experiences undergoing facial reconstructive surgery due to Treacher Collins; the film won a student Academy Award. The disorder was featured on the show Nip/Tuck, in the episode "Blu Mondae". TLCs Born Without a Face features Juliana Wetmore, who was born with the most severe case in medical history of this syndrome and is missing 30%–40% of the bones in her face.In 2010, BBC Three documentary Love Me, Love My Face covered the case of a man, Jono Lancaster, with the condition. In 2011, BBC Three returned to Jono to cover his and his partner Lauras quest to start a family, in So What If My Baby Is Born Like Me?, which first aired as part of a BBC Three season of programmes on parenting. The first film was replayed on BBC One shortly ahead of the second films initial BBC Three broadcast. Lancasters third BBC Three film, Finding My Family on Facebook, which looked at adoption, aired in 2011.In Wonder, a childrens novel, the main character is a child who has Treacher Collins syndrome. A 2017 film adaptation of Wonder, starring Julia Roberts, Owen Wilson and Jacob Tremblay, was released in November 2017.Alison Midstokke, who appears in the drama film Happy Face (2018), is an actress and activist who has the condition. See also
First arch syndrome
Franceschetti-Klein syndrome
Hearing loss with craniofacial syndromes

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Pimecrolimus is an immunomodulating agent of the calcineurin inhibitor class used in the treatment of atopic dermatitis (eczema). It is available as a topical cream, once marketed by Novartis (however, Galderma has been promoting the compound in Canada since early 2007) under the trade name Elidel. Medical uses
It has been proven to be effective in various inflammatory skin diseases, e.g., seborrheic dermatitis,  cutaneous lupus erythematosus, oral lichen planus,  vitiligo, and psoriasis. Tacrolimus and pimecrolimus are both calcineurin inhibitors and function as immunosuppressants. Side effects
In January 2006, the United States Food and Drug Administration (FDA) announced that Elidel packaging would be required to carry a black box warning regarding the potential increased risk of lymph node or skin cancer, as for the similar drug tacrolimus, whereas current practice by UK dermatologists is not to consider this a significant real concern and they are increasingly recommending the use of such new drugs.Importantly, although the FDA has approved updated black-box warning for tacrolimus and pimecrolimus, the recent report of the American Academy of Dermatology Association Task Force finds that there is no causal proof that topical immunomodulators cause lymphoma or nonmelanoma skin cancer, and systemic immunosuppression after short-term or intermittent long-term topical application seems an unlikely mechanism. Another recent review of evidence concluded that postmarketing surveillance shows no evidence for this systemic immunosuppression or increased risk for any malignancy. However, strong debates and controversies continue regarding the exact indications of immunomodulators and their duration of use in the absence of active controlled trials.