Hepatic porphyrias is a form of porphyria in which toxic porphyrin molecules build up in the liver. Hepatic porphyrias can result from a number of different enzyme deficiencies.Examples include (in order of synthesis pathway):
Acute intermittent porphyria
Porphyria cutanea tarda and Hepatoerythropoietic porphyria
Hereditary coproporphyria
Variegate porphyria

See also
Erythropoietic porphyria
Givosiran

References
External links

Porphyrias,+Hepatic at the US National Library of Medicine Medical Subject Headings (MeSH)
www.drugs-porphyria.com
www.porphyria-europe.com
The philosopher Simone Weil wrote that feeding the hungry when you have resources to do so is the most obvious of all human obligations. She says that as far back as Ancient Egypt, many believed that people had to show they had helped the hungry in order to justify themselves in the afterlife. Weil writes that Social progress is commonly held to be first of all, "...a transition to a state of human society in which people will not suffer from hunger." Social historian Karl Polanyi wrote that before markets became the worlds dominant form of economic organization in the 19th century, most human societies would either starve all together or not at all, because communities would invariably share their food.While some of the principles for avoiding famines had been laid out in the first book of the Bible, they were not always understood. Historical hunger relief efforts were often largely left to religious organizations and individual kindness. Even up to early modern times, political leaders often reacted to famine with bewilderment and confusion. From the first age of globalization, which began in the 19th century, it became more common for the elite to consider problems like hunger in global terms. However, as early globalization largely coincided with the high peak of influence for classical liberalism, there was relatively little call for politicians to address world hunger.In the late nineteenth and early twentieth century, the view that politicians ought not to intervene against hunger was increasingly challenged by campaigning journalists.