"Spurious hermaphroditism" was coined in 1836 by J. Y. Simpson.Although "pseudohermaphroditism" persisted in the International Classification of Diseases, Versions 9 (ICD-9) and 10 (ICD-10) as 752.7 (Indeterminate sex and pseudohermaphroditism) and Q56 (Interdeterminate sex and pseudohermaphroditism), it has since been removed in the eleventh version (ICD-11), in favor of LD2A.Y (Other specified malformative disorders of sex development).Some experts have indicated that both pseudohermaphroditism (also called false hermaphroditism) and true hermaphroditism are outdated, confusing, and potentially pejorative, indicating replacement with "disorders of sex development", "disorders of sexual development", "differences of sex development" (all abbreviated as DSD) or "intersex".Additionally, intersex activists have noted that: "The qualifiers pseudo and true are even more harmful [than hermaphrodite on its own], because they imply a sort of authenticity, or lack of same, that carry powerful emotional baggage". Dreger et al had also noted that "division of many intersex types into true hermaphroditism, male pseudohermaphroditism, and female pseudohermaphroditism is scientifically specious and clinically problematic". See also
(DoDI) 6130.03, 2018, section 5, 13f and 14m
Disorders of sex development
Intersex medical interventions
Diophantus of Abae
Callon of Epidaurus
Complete Androgen Insensitivity Syndrome

References


== External links ==
Clofazimine, sold under the brand name Lamprene, is a medication used together with rifampicin and dapsone to treat leprosy. It is specifically used for multibacillary (MB) leprosy and erythema nodosum leprosum. Evidence is insufficient to support its use in other conditions though a retrospective study found it 95% effective in the treatment of Mycobacterium avium complex (MAC) when administered with a macrolide and ethambutol, as well as the drugs amikacin and clarithromycin. However, in the United States, clofazimine is considered an orphan drug, is unavailable in pharmacies, and its use in the treatment of MAC is overseen by the Food and Drug Administration. It is taken orally.Common side effects include abdominal pain, diarrhea, itchiness, dry skin, and change in skin color. It can also cause swelling of the lining of the gastrointestinal tract, increased blood sugar, and sensitivity to the sun. It is unclear if use during pregnancy is safe. Clofazimine is a phenazine dye and is believed to work by interfering with DNA.Clofazimine was discovered in the 1950s at Trinity College, Dublin, and approved for medical use in the United States in 1986. It is on the World Health Organizations List of Essential Medicines. In the United States it is not available commercially but can be obtained from the US Department of Health and Human Services. Medical uses
The primary use of clofazimine is for the treatment of leprosy.