Symptoms accumulate over several months and include fever, cough, difficulty breathing, wheezing, and weight loss. Individuals with chronic eosinophilic pneumonia are often misdiagnosed with asthma before the correct diagnosis is made. Eosinophilic pneumonia due to medications or environmental exposures is similar and occurs after an exposure to a known offending agent. Eosinophilic pneumonia due to parasitic infections has a similar prodrome in addition to a host of different symptoms related to the variety of underlying parasites. Eosinophilic pneumonia in the setting of cancer often develops in the context of a known diagnosis of lung cancer, cervical cancer, or other certain types of cancer. Pathophysiology
Eosinophilic pneumonia can develop in several different ways depending on the underlying cause of the disease. Eosinophils play a central role in defending the body against infection by parasites. Many diseases, such as asthma and eczema, are caused when eosinophils overreact to environmental triggers and release an excess of chemicals, e.g., cytokines and histamine. The common characteristic among different causes of eosinophilic pneumonia is eosinophil overreaction or dysfunction in the lungs. Medications and environmental exposures
Medications, substance abuse, and environmental exposures may all trigger eosinophil dysfunction. Medications such as nonsteroidal anti-inflammatory drugs (e.g., ibuprofen), nitrofurantoin, phenytoin, L-tryptophan, daptomycin and ampicillin, and drugs of abuse such as inhaled heroin and cocaine may trigger an allergic response which results in eosinophilic pneumonia. Chemicals such as sulfites, aluminum silicate, and cigarette smoke can cause eosinophilic pneumonia when inhaled.
Timolol can also lead to fainting, congestive heart failure, depression, confusion, worsening of Raynauds syndrome and impotence.Side effects when given in the eye include: burning sensation, eye redness, superficial punctate keratopathy, corneal numbness. Formulations
It is available in tablet and liquid formulations.For ophthalmic use, timolol is also available combined:

with carbonic anhydrase inhibitors:
timolol and brinzolamide
timolol and dorzolamide
with α2 agonists:
timolol and brimonidine
with prostaglandin analogs:
timolol and latanoprost
timolol and travoprost

Brand names
Timolol is marketed under many trade names worldwide. Timolol eye drops are marketed under the brand name Istalol among others. References
External links
"Timolol". Drug Information Portal. U.S. National Library of Medicine. "Timolol Ophthalmic". Drug Information Portal. U.S. National Library of Medicine. "Timolol maleate". Drug Information Portal. U.S. National Library of Medicine. "Timolol Ophthalmic". MedlinePlus.