In contrast, magnetization transfer ratio and the diffusion coefficient show a loss of tissue in the rings of the lesion. Lesions under MRI
The features of the MRI and the characteristics of the lesion can be correlated when a biopsy has been taken, providing a way to standardize the future MRI diagnosisBalós concentric sclerosis lesions can be distinguished from normal lesions on MRI showing alternating hypointense and hyperintense layersBalós concentric lesions can be viewed using the myelin water imaging techniques. This is a special MRI sequence that shows the myelins percentage of water content.Pattern III lesions, including Baló lesions, have a specific initiation pattern under MRI (MRILIP) consisting in showing Gadolinium enhancement before FLAIR MRI appearance.Under 7-Tesla MRI Ball lesions show a center vein, like in MS. Treatment
Treatment with corticosteroids is usual to relieve inflammation. Epidemiology
The disease is more common in Chinese and Filipino populations (both Asiatic) than in caucasoids.Balo-like lesions have been reported to appear also in Tumefactive inflammatory leukoencephalopathy

Associations
A possible association with psoriasis and autoimmune thyroiditis has been reported

Pattern III (Baló-like) demyelinating spectrum
Baló-like lesions were classified as MS lesion pattern III in the MS spectrum. They have been reported alone, but also associated to standard multiple sclerosis, neuromyelitis optica, CADASIL and progressive multifocal leukoencephalopathyThere is an overlap between what is considered Baló concentric sclerosis and some atypical cases of multiple sclerosis. A special subtype of multiple sclerosis presents Baló-like lesions (pattern III lesions) creating an intersection between these two conditions.Some patients with BCS present oligoclonal bands while others do not.
Nature Clinical Practice Neurology. 3 (9): E1. doi:10.1038/ncpneuro0619. PMID 17805242. S2CID 33938721. == External links ==