These lung injuries can be contributed by water aspiration and also irritants present in the water such as microbial pathogens leading to complications such as lung infection that can develop in adult respiratory disease syndrome later on in life. Some literature suggests that occurrences of drowning can lead to acute kidney injury from lack of blood flow and oxygenation due to shock and global hypoxia. These kidney injury can cause irreversible damage to the kidneys and may require long-term treatment such as renal replacement therapy. Infant Risk
Children are overrepresented in drowning statistics, with children aged 0–4 years old having the highest number of deaths due to unintentional downing. In 2019 alone 32,070 children between the ages 1–4 years old died as a result of unintentional drowning, equating to an age-adjusted fatality of 6.04 per 100,000 children. Infants are particularly vulnerable because while their mobility develops quickly, their perception concerning their ability for locomotion between surfaces develops slower. An infant can have full control of their movements, but simply wont recognize that water does not provide the same support for crawling as hardwood floors would. An infant’s capacity for movement needs to be met with an appropriate perception of surfaces of support (and avoidance of surfaces that do not support locomotion) to avoid drowning. By crawling and interacting with their environment, infants learn to distinguish surfaces offering support for locomotion from those that do not, and their perception of surface characteristics will improve, as well as their perception of falls risk, over several weeks.
Patients undergoing therapy to suppress the immune system are at risk for hemorrhagic cystitis due to either the direct effects of chemotherapy or activation of dormant viruses in the kidney, ureter, or bladder. Diagnosis
Diagnosis is made by history and examination.In immunocompromised patients, pus is present in the urine but often no organism can be cultured. In children, polymerase chain reaction sequencing of urine can detect fragments of the infectious agent.The procedure differs somewhat for women and men. Laboratory testing of urine samples now can be performed with dipsticks that indicate immune system responses to infection, as well as with microscopic analysis of samples. The presence of hematuria, or blood in the urine, may indicate acute UTIs, kidney disease, kidney stones, inflammation of the prostate (in men), endometriosis (in women), or cancer of the urinary tract. In some cases, blood in the urine results from athletic training, particularly in runners. Treatment
Unfortunately mesna  is ineffective as a treatment once hemorrhagic cystitis has developed. Although rare, once a case of radiation-induced hemorrhagic cystitis is diagnosed there is no empirically-proven treatments to heal this type of condition, which can severely degrade a patients quality of life and might possibly lead to kidney failure with risk of death. Viral hemorrhagic cystitis in children generally spontaneously resolves within a few days. The first step in the treatment of HC should be directed toward clot evacuation. Bladder outlet obstruction from clots can lead to urosepsis,  bladder rupture, and kidney failure.