Its still possible to drown even after learning to swim (because of the state of the water and other circumstances), so its recommended to choose swimming places that are safe and kept under surveillance. Additional education: The WHO recommends training the general public in first-aid for the drowned, cardiopulmonary resuscitation (CPR), and to behave safely when in the water. It is recommended to teach those who cannot swim to keep themselves away from deep waters. Pool fencing: Every private and public swimming pool should be fenced and enclosed on every side, so no person can access the water unsupervised. The "Raffarin law", applied in France in 2003, forced the fencing of pools. Pool drains: Swimming pools often have drainage systems to cycle the water. Drains without covers can injure swimmers by trapping hair or other parts of the body, leading to immobilization and drowning. Drains should not suction too strongly. It is recommended for a pool to have many small drainage holes instead of a single large one. Periodic revisions are required to certify that the system is working well. Caution with certain conditions: Some conditions require one to be cautious when near water. For example, epilepsy and other seizure disorders may increase the possibility of drowning during a convulsion, making it more dangerous to swim, dive, and bathe. It is recommended that people with these conditions take showers rather than baths and are taught about the dangers of drowning. Alcohol or drugs: Alcohol and drugs increase the probability of drowning.
The elimination half-life range of quazepam is between 27 and 41 hours. Mechanism of action
Quazepam modulates specific GABAA receptors via the benzodiazepine site on the GABAA receptor. This modulation enhances the actions of GABA, causing an increase in opening frequency of the chloride ion channel which results in an increased influx of chloride ions into the GABAA receptors. Quazepam, unique amongst benzodiazepine drugs selectively targets type1 benzodiazepine receptors which results reduced sleep latency in promotion of sleep. Quazepam also has some anticonvulsant properties. EEG and sleep
Quazepam has potent sleep inducing and sleep maintaining properties. Studies in both animals and humans have demonstrated that EEG changes induced by quazepam resemble normal sleep patterns whereas other benzodiazepines disrupt normal sleep. Quazepam promotes slow wave sleep. This positive effect of quazepam on sleep architecture may be due to its high selectivity for type1 benzodiazepine receptors as demonstrated in animal and human studies. This makes quazepam unique in the benzodiazepine family of drugs. Drug misuse
Quazepam is a drug with the potential for misuse. Two types of drug misuse can occur, either recreational misuse where the drug is taken to achieve a high, or when the drug is continued long term against medical advice. References
External links
"Quazepam". Drug Information Portal. U.S. National Library of Medicine.