destitute or deprived of inhabitants; deserted; uninhabited; hence, gloomy; as, a desolate isle; a desolate wilderness; a desolate house.-laid waste; in a ruinous condition; neglected; destroyed; as, desolate altars.-left alone; forsaken; lonely; comfortless.-lost to shame; dissolute.-destitute of; lacking in.-to make desolate; to leave alone; to deprive of inhabitants; as, the earth was nearly desolated by the flood.-to lay waste; to ruin; to ravage; as, a fire desolates a city.