to destroy the organic texture and vital functions of; to produce gangrene in.-to destroy the active powers or essential qualities of; to change by chemical action.-to deaden by religious or other discipline, as the carnal affections, bodily appetites, or worldly desires; to bring into subjection; to abase; to humble.-to affect with vexation, chagrin, or humiliation; to humble; to depress.-to lose vitality and organic structure, as flesh of a living body; to gangrene.-to practice penance from religious motives; to deaden desires by religious discipline.-to be subdued; to decay, as appetites, desires, etc.