Given $N$ positive integers such that the greatest common divisors of all nonempty subsets of them are pairwise distinct. What is the smallest number of prime factors of the product of all $N$ numbers?

[i] Proposed by Aleksandr Golovanov [/i]
1. **Understanding the Problem:**
   We are given \( N \) positive integers such that the greatest common divisors (GCDs) of all nonempty subsets of them are pairwise distinct. We need to find the smallest number of prime factors of the product of all \( N \) numbers.

2. **Case Analysis for \( N = 1 \):**
   - If \( N = 1 \), we have only one number. The GCD of the single number with itself is the number itself. To satisfy the condition of distinct GCDs, the number must be 1 (since 1 has no prime factors).
   - Therefore, for \( N = 1 \), the smallest number of prime factors is \( 0 \).

3. **Case Analysis for \( N \geq 2 \):**
   - Assume there is a solution with \( N - 1 \) prime factors. Let these primes be \( p_1, p_2, \ldots, p_{N-1} \).
   - Let our numbers be \( a_1, a_2, \ldots, a_N \).
   - We will build a set \( S \) as follows:
     - For each \( i = 1, 2, \ldots, N-1 \), pick an integer \( a_j \) such that \( a_j \) does not belong to \( S \) and \( v_{p_i}(a_j) \) is minimal among those \( a_k \) not in \( S \).
     - Add this \( a_j \) to \( S \).
   - By the end of this algorithm, we have \( |S| = N-1 \). Let the elements of \( S \) be \( s_1, s_2, \ldots, s_{N-1} \), and let \( s \) be the number not in \( S \).
   - Now, consider \( \gcd(s_1, s_2, \ldots, s_{N-1}) \) and \( \gcd(s_1, s_2, \ldots, s_{N-1}, s) \). These two GCDs must be distinct, but they are not, which leads to a contradiction.

4. **Construction with \( N \) Prime Factors:**
   - Let \( P \) be the product of the first \( N \) primes, i.e., \( P = p_1 p_2 \cdots p_N \).
   - Define \( a_i = \frac{P}{p_i} \) for all \( 1 \leq i \leq N \), where \( p_i \) is the \( i \)-th prime.
   - Each number \( a_i \) can be thought of as a binary string of \( N \) bits, with \( 1 \) everywhere except in the \( i \)-th place.
   - The GCD of any subset of these numbers is the AND of the corresponding binary strings, which is unique for each subset.

5. **Conclusion:**
   - The smallest number of prime factors of the product of all \( N \) numbers is \( N \) for \( N \geq 2 \).

The final answer is \( \boxed{ N } \) for \( N \geq 2 \) and \( 0 \) for \( N = 1 \).