1. (6 points) Calculate: $1.25 \times 6.21 \times 16+5.8=$
【Solution】Solve: $1.25 \times 6.21 \times 16+5.8$
$$
\begin{array}{l}
=(1.25 \times 8) \times(2 \times 6.21)+5.8 \\
=10 \times 12.42+5.8 \\
=124.2+5.8 \\
=130
\end{array}
$$

Therefore, the answer is: 130