1. Find the smallest positive integer $n$, such that there exist $n$ distinct positive integers $s_{1}, s_{2}, \cdots, s_{n}$, satisfying
$$
\left(1-\frac{1}{s_{1}}\right)\left(1-\frac{1}{s_{2}}\right) \cdots\left(1-\frac{1}{s_{n}}\right)=\frac{51}{2010} .
$$
1. Suppose the positive integer $n$ satisfies the condition, and let $s_{1}=39$.
Thus, $n \geqslant 39$.
Below, we provide an example to show that $n=39$ satisfies the condition.
Take 39 different positive integers:
$$
2,3, \cdots, 33,35,36, \cdots, 40,67,
$$

which satisfy the given equation.
In conclusion, the minimum value of $n$ is 39.