What is the ones digit of\[222,222-22,222-2,222-222-22-2?\]$\textbf{(A) } 0\qquad\textbf{(B) } 2\qquad\textbf{(C) } 4\qquad\textbf{(D) } 6\qquad\textbf{(E) } 8$
We can rewrite the expression as \[222,222-(22,222+2,222+222+22+2).\]
We note that the units digit of the addition is $0$ because all the units digits of the five numbers are $2$ and $5*2=10$, which has a units digit of $0$.
Now, we have something with a units digit of $0$ subtracted from $222,222$. The units digit of this expression is obviously $2$, and we get $\boxed{B}$ as our answer.
i am smart 
~ Dreamer1297