Find all real solutions of the system of equations
$$\begin{cases}  x^2 + y^2 + u^2 + v^2 = 4 \\ xu + yv + xv + yu = 0  \\ xyu + yuv + uvx + vxy = - 2 \\ xyuv = -1 \end{cases}$$
We are given the system of equations:
\[
\begin{cases}
x^2 + y^2 + u^2 + v^2 = 4 \\
xu + yv + xv + yu = 0 \\
xyu + yuv + uvx + vxy = -2 \\
xyuv = -1
\end{cases}
\]

1. **Analyzing the second equation:**
   \[
   xu + yv + xv + yu = 0
   \]
   This can be factored as:
   \[
   (x + y)(u + v) = 0
   \]
   This implies either \(x + y = 0\) or \(u + v = 0\). We will consider the case \(u + v = 0\). The case \(x + y = 0\) can be handled analogously.

2. **Substituting \(v = -u\):**
   \[
   v = -u
   \]
   Substituting \(v = -u\) into the equations, we get:
   \[
   x^2 + y^2 + u^2 + (-u)^2 = 4 \implies x^2 + y^2 + 2u^2 = 4
   \]
   \[
   xy(-u) + y(-u)u + u(-u)x + (-u)xy = -2 \implies -xyu - yu^2 - u^2x - uxy = -2
   \]
   Simplifying the third equation:
   \[
   -2xyu - 2yu^2 = -2 \implies xy + yu = 1
   \]
   \[
   xyuv = -1 \implies xy(-u)u = -1 \implies -xyu^2 = -1 \implies xyu^2 = 1
   \]

3. **Solving for \(xy\) and \(u\):**
   \[
   xyu^2 = 1 \implies u^2 = \frac{1}{xy}
   \]
   Substituting \(u^2 = \frac{1}{xy}\) into the first equation:
   \[
   x^2 + y^2 + 2 \left(\frac{1}{xy}\right) = 4
   \]
   Let \(xy = a\):
   \[
   x^2 + y^2 + \frac{2}{a} = 4
   \]

4. **Using the identity \(x^2 + y^2 = (x + y)^2 - 2xy\):**
   \[
   x + y = 2a \implies x^2 + y^2 = (2a)^2 - 2a = 4a^2 - 2a
   \]
   Substituting this into the equation:
   \[
   4a^2 - 2a + \frac{2}{a} = 4
   \]
   Multiplying through by \(a\) to clear the fraction:
   \[
   4a^3 - 2a^2 + 2 = 4a \implies 4a^3 - 2a^2 - 4a + 2 = 0
   \]
   Factoring the cubic equation:
   \[
   (a - 1)(a + 1)(2a - 1) = 0
   \]
   Thus, the possible values for \(a\) are:
   \[
   a = 1, \quad a = -1, \quad a = \frac{1}{2}
   \]

5. **Finding corresponding values for \(x\) and \(y\):**
   - For \(a = 1\):
     \[
     xy = 1, \quad x + y = 2 \implies x, y \text{ are roots of } t^2 - 2t + 1 = 0 \implies (t - 1)^2 = 0 \implies x = 1, y = 1
     \]
   - For \(a = -1\):
     \[
     xy = -1, \quad x + y = -2 \implies x, y \text{ are roots of } t^2 + 2t - 1 = 0 \implies t = -1 \pm \sqrt{2} \implies x = -1 + \sqrt{2}, y = -1 - \sqrt{2}
     \]
   - For \(a = \frac{1}{2}\):
     \[
     xy = \frac{1}{2}, \quad x + y = 1 \implies x, y \text{ are roots of } t^2 - t + \frac{1}{2} = 0 \implies t = \frac{1 \pm i\sqrt{3}}{2} \implies \text{No real solutions}
     \]

The final answer is \( \boxed{ (x, y, u, v) = (1, 1, 1, -1), (-1 + \sqrt{2}, -1 - \sqrt{2}, 1, -1) } \)