	From 11–12 October 1942, it led DesDiv 31 against Guadalcanal, accompanied by the battleships and and aircraft carriers and , CruDiv 4's , and CruDiv 5's . "Isuzu" provided cover with DesDivs 15 and 31 and also fired on Marine batteries on Tulagi Island during the Bombardment of Henderson Field, Guadalcanal by the "Kongō" and "Haruna".