Grenzach-Wyhlen is a municipality in Lörrach in Baden-Württemberg, Germany. It is on the right bank of the Rhine, 7 km east of Basel, and 8 km south of Lörrach. The municipality has borders to Inzlingen and Rheinfelden (Baden) in Germany, and Riehen (BS), Birsfelden (BL) and Kaiseraugst (AG) in Switzerland.