	CgNa has an effect on tetrodotoxin-sensitive sodium channels. More specifically, in mammals it affects isoforms rNav1.3/β1, mNav1.6/β1; it has lower affinity to the cardiac isoform hNav1.3/β1. The toxin seems to have no effect on other mammalian Nav channel subtypes, although its effect on subtype rNav1.1 and Nav1.9 has not been tested.