Most marsupial and eutherian mammals have a reproductive cycle known as the oestrous cycle (U.S: estrous cycle). Females are sexually active only during the oestrous stage, when they are 'on heat' for a few days each month. If an ovum is not fertilized, the endometrium (uterus lining) is resorbed. Oestrus cycles may occur once or twice a year, or many times a year. Each group of mammals has its own frequency.