Given the extensive literature and sequence data from treated individuals infected with HIV-1 subtype B, patterns of mutations associated with resistance to specific drugs have become increasingly recognizable, making it possible to recommend alternative treatment regimens; however, such data are generally not available for non-B subtypes.
Le développement de la résistance à ces médicaments résulte d’une combinaison de l’échec d’un traitement virologique et d’une suppression virale incomplète.