Of Irish-Catholic descent and a convent-school education, Leprohon published her first poetry, at age 17, in the Literary Garland, followed by serialized novels of manners set in England, published annually from 1848 to 1851.
Par la suite, son regard se tourne vers la société québécoise. L'action de The Manor House of de Villerai (publié sous forme de feuilleton dans le The Family Herald ; trad.