Cleavage and recyclization of the lactone ring of pilocarpine (1) and of isopilocarpine (2) in D2O with varying pD have been studied by 13C nmr spectroscopy.
On a étudié, par spectroscopie rmn du 13C, la coupure et la recyclisation du cycle lactonique de la pilocarpine (1) et de l'isopilocarpine (2) dans la D2O à des pD variables.