Focus on Virgin Enthroned with Saints (Signorelli) and explore the History.
In 1490-1492 Signorelli was in Volterra, a city under Florentine control, under the patronage of the House of Medici. Aside from this Madonna, he painted   an Annunciation, a Circumcision of Christ and, perhaps, the Portrait of Man.
Annunciation Circumcision of Christ Florentine Portrait of Man House of Medici Volterra