question: Q:An inpatient psychiatrist recently had two patients who developed serious gastrointestinal infections while taking clozapine. He was concerned that his patients had developed agranulocytosis, a relatively rare but dangerous adverse event associated with clozapine. When the psychiatrist checked the absolute neutrophil count (ANC) of both patients, one was 450/mm3, while the other was 700/mm3 (N=1,500/mm3). According to the clozapine REMS (Risk Evaluation and Mitigation Strategy) program, severe neutropenia in clozapine recipients has often been defined as an absolute neutrophil count (ANC) less than 500/mm3. Changing the cutoff value to 750/mm3 would affect the test performance of ANC with regard to agranulocytosis in which of the following ways?? 
  {'A': 'Increased positive predictive value', 'B': 'Decreased true positives', 'C': 'Unchanged specificity', 'D': 'Increased false positives', 'E': 'Decreased sensitivity\n"'},