question: Q:A 10-month-old boy is referred to the hospital because of suspected severe pneumonia. During the first month of his life, he had developed upper airway infections, bronchitis, and diarrhea. He has received all the immunizations according to his age. He failed to thrive since the age of 3 months. A month ago, he had a severe lung infection with cough, dyspnea, and diarrhea, and was unresponsive to an empiric oral macrolide. Upon admission to his local hospital, the patient has mild respiratory distress and crackles on auscultation. The temperature is 39.5°C (103.1°F), and the oxygen saturation is 95% on room air. The quantitative immunoglobulin tests show increased IgG, IgM, and IgA. The peripheral blood smear shows leukocytosis and normochromic normocytic anemia. The chloride sweat test and tuberculin test are negative. The chest X-ray reveals bilateral pneumonia. The bronchoalveolar lavage and gram stain report gram-negative bacteria with a growth of Burkholderia cepacia on culture. The laboratory results on admission are as follows:
  Leukocytes 36,600/mm3
  Neutrophils 80%
  Lymphocytes 16%
    Eosinophils 1%
  Monocytes 2%
  Hemoglobin 7.6 g/dL
  Creatinine 0.8 mg/dL
  BUN 15 mg/dL
  Which of the following defects of neutrophil function is most likely responsible?? 
  {'A': 'Absent respiratory burst', 'B': 'Leukocyte adhesion molecule deficiency', 'C': 'X-linked agammaglobulinemia', 'D': 'Phagocytosis defect', 'E': 'Lysosomal trafficking defect'},