question: my grandma's bp is 204 over 92 and she takes lisinopril -her doc just increased the dose from 10mgs to 20 a day... however it seems by the end of the day her bp goes back up to the 204 over 92.  We just started the 20 mgs today... she took one at 5am (bp was high) and another at 9:30 am.  Bp was fine all day.  Just took it before she went to bed and it was high... we will call and schedule an appointment with her doc tomorrow for this week.  She has had a history of high bp.  Should we space out the pills 12 hours apart?