question: My husband suffers from depression . He was injured at work and we had to deal with Worker s Comp. for 22 months. He had to have total knee replacement and the surgeon has told him he won t be able to return to work. He has applied for dissability but because he s only 47, he was turned down. We have a lawyer and feel he s doing a good job. My husband feels like he should be taking care of his family and of course, staying inside all day certainly doesn t help. Our doctor has tried him on Celexa (29 mg) and Effexor (150 mg). He had 1 refill left on the Effexor so he started taking it again. With all the medicines out there, we don t know which might be best for him. He has an appointment next week with anothe doctor to get a second opinion. He has been on Metformin and Lesinopril but has stopped those since his weight loss from close to 270 down to 217. He s such a wonderful person and am not giving up on getting him help. He just gets very frustrated trying different meds. Any advice you can give will be greatly appreciated! Thanks in advance. I m sorry I can t pay this since I am the only one working. But thank you anyway.