question: Humanity could face the COVID-19 epidemic to crystallize a sustainable future for the water, hygiene, and food sectors. The epidemic has affected the sustainability of water, food, and health institutions in Egypt. Water consumption levels have increased in the agricultural sector to ensure food security. Regular handwashing is one of the most important measures to prevent the epidemic, and this has an impact on water consumption. The purpose of the research is to reshape sustainable development trajectory due to COVID-19 pandemic in Egypt through three interdependent phases: the first is devoted to forecast how the pandemic could be spreading in Egypt, the second is assigned to foresee implications and consequences of the pandemic on water, food, and human activities, and the third is dedicated to exploring how Egypt could utilize non-conventional water resources as a precious resource to fight the pandemic and explore sustainable recovery strategies. The results could be summarized as the diffusion of COVID-19 pandemic may be considered a group of evolutionary processes. The vision of growth to a limit may be applied; the number of cases of COVID-19 grows rapidly, but the growth will be reduced due to negative feedback signals from the environment. The paper concludes that the COVID-19 epidemic could be addressed by enhancing the water sector to better cope with future shocks. Water, food, health, and work opportunities could be provided and managed sustainably. The need to provide water to wash the hands of all citizens has been emphasized to fight the coronavirus. Non-conventional water resources could be an engine to ambitious plans to drive economic growth through megaprojects. Egypt would enable transforming this crisis into an opportunity to accelerate the pace of action towards achieving Sustainable Development Goals.