question: hiMy wife is 24 week pregnant. during last week ultrasound Dr' told us there is single echogenic foci in the left ventrical of baby's heart. As per her it is a marker of Trisomy 21.  however the definative test to ascertain is amniocentesis. >we are worried after this as amnio carries risk of miscarriage at 1:200.  we want to know how much serious is this finding are we are worrying too much? does risk of having down sydrome baby is increased for my wife and if by how much.  my wife haven't undergone tripple screen test. does Down syndrome is heridetry as wife parents are perfectly normal.