question: Q:A 33-year-old woman comes to the physician for week-long episodes of headaches that have occurred every four weeks for the last year. During these episodes she also has bouts of lower abdominal pain and breast tenderness. She is often irritable at these times. Her menses occur at regular 28-day intervals with moderate flow. Her last menstrual period was 3 weeks ago. She drinks two to five beers on social occasions and used to smoke a pack of cigarettes daily, but stopped 6 months ago. Her mother and sister have hypothyroidism. Physical examination shows no abnormalities. Which of the following is most likely to confirm the diagnosis?? 
  {'A': 'Detailed psychosocial assessment', 'B': 'Therapeutic trial with nicotine gum', 'C': 'Assessment of thyroid hormones', 'D': 'Serial measurements of gonadotropin levels', 'E': 'Maintaining a menstrual diary'},