question: Q:A 57-year-old woman comes to the physician because of increasing wrinkles on her face and sagging skin. She says that her skin used to be smooth and firm. Examination shows diffuse xerosis and mild atrophy, laxity, and fine wrinkles on the periorbital skin. Which of the following processes is most likely involved in the development of this patient's skin findings?? 
  {'A': 'Decrease in lysyl oxidase activity', 'B': 'Decrease in elastin fiber assembly', 'C': 'Increase in fibroblast activity', 'D': 'Increase in lipofuscin deposition', 'E': 'Decreased crosslinking of collagen fibrils'},