question: Background: In response to the COVID-19 pandemic, the Oxford Adult CF Centre offered virtual clinics using the NHS Attend Anywhere platform from June 2020. We surveyed patient and staff experience. Methods: An anonymous online patient survey was added to appear at the end of all CF virtual consultations from July to November 2020. A separate anonymous staff survey was distributed by email to all members of the CF multidisciplinary team. Results: 136 responses were received (patient population of 141) and 12/19 (62%) of staff responded. 71% of patients rated a virtual review a very reasonable alternative to face-to-face and 83% felt all their clinical needs were met. 98% rated how comfortable they were to talk to clinicians as 4 or 5/5. 83% staff felt they could provide an acceptable standard of review to most patients. When asked if they could provide a high standard of review, 17% felt they could to most patients, with 58% feeling they could to some patients only. Time efficiency and patient attendance at virtual clinics were perceived as superior to face-to face. 86% of patients rated their satisfaction with the technology as 4 or 5/5, with 100% staff rating as 4/5. 11 negative patient comments related to technology. Poor sound quality and video lag were the main concerns identified by both patients and staff. 82% of patients would like to continue using virtual reviews in future and 100% staff wanted this to be an option for some appointments. Routine clinic visits were rated most popular appointments to be virtual in future by staff and patients. Conclusion: Virtual clinics have been well received by the majority of our adult CF patients during the COVID-19 pandemic. Patients and staff wanted to use virtual reviews in future, although both recognised this is not always suitable for all appointments.