question: Curriculum leaders in medical education responded to the COVID-19 pandemic in 2020 by converting in-person formal learning (lectures, small groups, etc.) to on-line formats, removing medical students from clinical environments, creating interim learning opportunities to replace in-person clinical learning, developing plans to keep learners safe for their eventual return to clinical environments, and restructuring schedules. In this article, we describe and discuss five strategic implications of the pandemic's impact on curriculum development in medical education.