question: Hello doctor, I was diagnosed with MGUS (IGA) when I was seeing a neurologist for some burning in my palms of my hands and soles of my feet which is awful at night and prohibits me from sleeping. This has been going on for six months but has gotten worse so I went back to the neurologist. Neurologist ordered an MRI for next week to see if the six white matter brain lesions I had were changed. Since the MGUS, I followed up with hematologist three times and he said my numbers are so low they do not show up on M spike. All other labs were normal. I saw a dermatologist to see if burning was skin related. She said no maybe vascular so I saw a cardiovascular doctor who is also running tests. I also saw a rheumatologist so does not believe it is rheumatology based on blood work. My question is if my numbers at hematology were so low they do not show M spike could they be causing the random burning in the palms of my hands and soles of my feet. Just want answers and as of right now I get the neuro saying it is MGUS and hematologist saying it neuro. I am scared and exhausted. Please help. My Primary complaint is burning red palms of my hands and red soles of my feet, not fire engine red just slightly red. My hands tend to get a little swollen on the top and my veins are swollen and then it goes away and my hands are looking normal and are cold sometimes. Well, it happens all day regardless of what I am doing with the activity is it randomly pops up definitely when I am moving around or running the vacuum or doing something like that but it is really bad at night. So far I have done myeloma profile, CBC, ANA, and CRP tests.