question: Two versions of radioisotope carbon-14 labelled chlorantraniliprole, 3-bromo-N-(4-chloro-2-methyl-6-(methyl[carbonyl-14C]carbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-1 H-pyrazole-5-carboxamide(2, 55.6 mCi, radiochemical purity 99.8%, chemical purity 99.1%, specific activity 52.45 mCi/mmol) and 3-bromo-N-(4-chloro-2-methyl-6-(methylcarbamoyl)phenyl)-1-(3-chloropyridin-2-yl)-1 H-pyrazole-5-[carbonyl-14C]carboxamide(3, 58.6 mCi, radiochemical purity 99.6%, chemical purity98.4%, specific activity 52.30 mCi/mmol), were synthesized from barium [14C]carbonate via eight-step radioactive reactions including Grignard reaction, nucleophilic substitution, amination reaction, condensation, and etc. Pure C-14 labelled products were obtained after RP-HPLC purification in the overall radiochemical yield of 32% and 52%, respectively. The products were characterized by ESI-MS,1 H NMR and HPLC-FSA. Their technical data was determined by TLC-IIA, HPLC-LSC, HPLCFSA/PDA/MS and LSC, respectively. These products could be used as radiotracers and meet the requirement of the study on the metabolism of chlorantraniliprole for registration in China.