question: Q:A 3-year-old girl is brought to the emergency room because of a 5-day history of high fever and fatigue. During this time she has been crying more than usual and eating less. Her mother says that the child has also complained about pain in her arms and legs for the past 3 days. She was born at term and has been otherwise healthy. She appears ill. Her temperature is 39.5°C (103.1°F), pulse is 128/min, and blood pressure is 96/52 mm Hg. The lungs are clear to auscultation. A grade 3/6 systolic murmur is heard at the apex. There is mild tenderness to palpation of the left upper quadrant with no guarding or rebound. The spleen is palpated 3 cm below the left costal margin. There is no redness or swelling of the joints. Laboratory studies show:
  Hemoglobin 11.8 g/dL
  Leukocyte count 16,300/mm3
  Platelet count 220,000/mm3
  Erythrocyte sedimentation rate 50 mm/h
  Serum
  Glucose 96 mg/dL
  Creatinine 1.7 mg/dL
  Total bilirubin 0.4 mg/dL
  AST 18 U/L
  ALT 20 U/L
  Urine
  Protein 2+
  RBC casts rare
  RBC 10/hpf
  WBC 1–2/hpf
  Which of the following is the most appropriate next step in management?"? 
  {'A': 'Administer intravenous vancomycin', 'B': 'Measure rheumatoid factors', 'C': 'Obtain 3 sets of blood cultures', 'D': 'Obtain a transesophageal echocardiography', 'E': 'Obtain a renal biopsy'},