question: Uganda continues extensive mobilization and administration of the Covid 19 vaccine to its people albeit some vaccine hesitancy with in the population. Amongst the health workers however, approximately 70% had received their first dose while 40% had received their second dose of the Covid-19 vaccine by September 2021 respectively. These figures represent a recognizable acceptance rate among health workers. Exploring motivators to vaccine uptake among health workers is vital for the governments general population vaccine rollout plan. We conducted 12 focus group discussions and 20 in-depth interviews with health workers (vaccinated and unvaccinated) to understand motivators to vaccine acceptance in their own perspective in central and eastern Uganda. Reported motivators to vaccine acceptance included; risk susceptibility/protection, fear of death and/or cost of treatment and experiences of Covid related grief. Other were trust in the vaccine, call to government policy and vaccine success stories elsewhere, real or perceived benefits of vaccination and peer influence. We recommend intensified dissemination of health worker tailor made tools/guides for information, education and communication about the Covid 19 vaccine. The tools need to emphasize the elicited themes/motivators. We also recommend use of peers who have taken up the vaccine and survived Covid-19 or got a mild form of the disease to elicit positive peer influence about the vaccine amongst health workers. The information dissemination and peer narratives could be done through the health workers social media platforms, union or association websites, personal statements, editorials or other media.