question: * Diagnosed with m in 2010 and initially treated with Hormonal injections, anti-androgen tablets and bisphosphonate ( Lucrin, Androcur to Casodex, Zometa)* Radiotherapy in 2011 for ?Bony pain* Started on Chemotherapy with Docetaxel (Textotere) 2013* Now rising PSA and evidence of disease progression on CT and Bone scan