question: OBJECTIVE: Describe the experience lived in an interdisciplinary follow-up care center for mastectomized women at a public university in Sao Paulo during the beginning of the COVID-19 pandemic METHOD: Experience report on the health care provided in the health center for mastectomized women RESULTS: The care was provided three times a week by an interdisciplinary health team The mentioned areas that cover the women care in the center: Physical, Psychological, Social Support and Health Education CONCLUSIONS: The attention by an interdisciplinary team becomes prevalent in the care of mastectomized women, since cancer and its treatment produce various changes in women's lives in the short and long term, so follow-up and support must be biopsychosocial, covering all areas that may be affected, especially during the pandemic