question: My wife is suffering from mild scleroderma, now the skin of face and neck have become very supple. she was treated with Methotrexate for 2 weeks.Now she has fibromyalgia symptoms with neuritic pain left leg and anaesthesia in left foot. Sural nerve biopsy was done which showed polyneuritis.She cant walk , becomes breathless.She has reflux oesophagitis, proved by endoscopy. Angiogram was done it is normal.She is on pregabalin 75 mg BD. She has mild pedal oedema. She has sleeplessness also.It is bizarre of symptoms.I will be glad if you can throw some light