question: I have liver mets, primary found in rectum was removed surgically. liver mets were found to be carcinoids. first treated with sandostatin 20mg/once a month. then larger 3 tumours were chemo embulised. since chromogranin kept on rising, sandostatin LAR was stopped and i have gone through 3 cycles of Lu177 PRRT in AIIMS. the tumours have increased 10% in last 9 months and chromogronin is 6 times normal values. it seems PRRT is not working. what next can be done? any latest development on this score . please advise