question: Hi doctor, Before three years, my mother was diagnosed with schizo depressive disorder, when she lost her husband. She is having irritable bowel syndrome and diabetes mellitus. Now at present, she is taking Nexito 10 mg (Escitalopram), Hexinor 2 mg (Trihexyphenidyl Hydrochloride) both taken during day and night and also taking Quetiapine 100 mg only at night for two weeks. Now, she is entirely unresponsive, does not answer the questions correctly, pretty unaware of her behavior, hallucinations, and there is a loss of memory (difficulties to remember at present). Before these medicines, she has been given Risperidone 4 mg (day and night), Procyclidine 5 mg (day and night) and Quetiapine 100 mg (at night). When she was taking these medicines, she felt panic, depressed. There was difficulty in sleeping. Then the doctor changed the medication. But with the current medicines also, the problems have raised. What can we do now, should we include Risperidone with the current drugs to alleviate the symptoms?