question: Q:A 33-year-old man is admitted to hospital with a 1-week history of productive bloody cough, weight loss, and nocturnal sweats. He is of a lower socioeconomic status and has a history of alcohol and drug abuse. On physical examination his vital signs are as follows: blood pressure is 130/70 mm Hg, heart rate is 89/min, respiratory rate is 18/min, and temperature is 37.9℃ (100.2℉). Physical examination is remarkable for a unilateral left-sided focus of diminished vesicular respiration and rales. X-ray shows a focus of infiltration in the upper portion of the left lung that is 2 cm in diameter with signs of cavitation. A nucleic acid amplification test is positive for M. tuberculosis. The patient is prescribed an anti-tuberculosis (TB) regimen that includes rifampin. Which target will be inhibited by rifampin, and which process will be disrupted?? 
  {'A': 'DNA-dependent DNA polymerase, transcription', 'B': 'DNA-dependent RNA polymerase, translation', 'C': 'DNA-dependent RNA polymerase, transcription', 'D': 'DNA-dependent DNA polymerase, translation', 'E': 'DNA-dependent RNA polymerase, splicing'},