question: Q:A 52-year-old man comes to the physician because of right knee pain and swelling for 2 days. Four days ago, he tripped at home and landed on his knees. He reports an episode of diarrhea 3 weeks ago that resolved after 4 days without treatment. He has a history of hypertension and hypercholesterolemia, and was recently diagnosed with parathyroid disease. He drinks 1–2 ounces of whiskey daily and occasionally more on weekends. His brother has ankylosing spondylitis. Vital signs are within normal limits. Examination of the right leg shows an abrasion below the patella. There is swelling and tenderness of the right knee; range of motion is limited by pain. Arthrocentesis of the right knee joint yields 15 mL of cloudy fluid with a leukocyte count of 26,300/mm3 (91% segmented neutrophils). Microscopic examination of the synovial fluid under polarized light shows rhomboid-shaped, weakly positively birefringent crystals. Which of the following is the strongest predisposing factor for this patient's condition?? 
  {'A': 'Dyslipidemia', 'B': 'Local skin abrasion', 'C': 'Alcohol consumption', 'D': 'Hyperparathyroidism', 'E': 'Recent gastrointestinal infection'},