question: Q:A 62-year-old woman comes to the physician because of a 2-month history of a rash on her ankles with intermittent itching. After the rash developed, she started applying a new scented lotion to her legs daily. She works as a cashier at a grocery store. She has type 2 diabetes mellitus and hypertension. Current medications include metformin and enalapril. Examination shows enlarged superficial veins of the right lower extremity and red-brown discoloration with indistinct margins over the medial ankles. There is 1+ edema in the lower extremities. Which of the following is the most likely cause of this patient’s skin findings?? 
  {'A': 'Bacterial spread through the superficial dermis', 'B': 'Contact of antigen with pre-sensitized T lymphocytes', 'C': 'Intracellular accumulation of sorbitol', 'D': 'Infection with dermatophyte', 'E': 'Dermal deposition of hemosiderin\n"'},