question: I just started taking prednisone yesterday for a viral infection. No fever. Sore throat and enlarged lymph nodes on the back of my neck. Last night I noticed red spots on my face but I thought I might just be getting an acne breakout. Now they are on my neck, arms, chest and back. They don t really itch and are not very close together. I ve taken prednisone before- about 6 months ago I had mono. Am I having an allergic reaction to it or is it probably something else?