question: I ve been having severe pain in my wrist when I move my thumb with swelling in the fatty tissue. At first I thought the pain was due to arthritis (I ll be 53 in Dec) but the pain has now become almost constant. I can no longer lift anything heavy because the pain is so bad. I m an accountant and the pain is really beginning to affect my job. I had a complete thyroidectomy done in 2003 due to hypothyroidism and recently (two weeks ago) had my thyroid bloodwork done and everything came back fine. I have no pain in my fingers or numbness. I had corpal tunnel surgery done 16 years ago. The pain is not at all like the pain of corpal tunnel.