question: hi   my uncle  took a callous off his big toe, he developed staph infection and is on antibiotics. If he goes off the medication the hole gets bigger. He is borderline diabetic but the Dr isn't putting him on insulin.  Is the hole not getting better because of the staph and or because he hasn't been given insulin??? He has been dealing with this for a yr and 1/2. HE HAS SEEN SEVERAL DR.S noone has been able to fix this hole in his big toe...last but not least  he has neuropathy of the feet.....   If I had this I would be crying in pain because the hole is big.Frustrated in Green Bay