question: Herein, we present the case of a 55-year-old patient who developed a severe zoster reaction after receiving the AstraZeneca COVID-19 vaccine. Although zoster reactivation has already been observed with various vaccines, the extent and length of this reaction raise serious concerns. Hopefully, the outcome of this patient was favorable. The case of this patient, who could have only received a single dose of the vaccine, suggests that immunity after this type of vaccine vanishes rapidly and booster shots will be of crucial importance in the future. [ FROM AUTHOR] Copyright of Our Dermatology Online / Nasza Dermatologia Online is the property of Our Dermatology Online and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)