question: I am having numbness and pain in my toes on each foot. Toes # 2 & 3. I have several medical conditions you should know. Fallopian tube cancer in remission, chronic headaches from a compressed trigeminal nerve in the root of my brain (I receive nerve block shots for them), CKD stage 2, Barrett’s esophagus, and hypothyroidism. I also deal with severe fatigue, memory issues and shortness of breath. My question is should I be concerned about this pain and numbness in my toes or is this just a side effect of nerve block shots, especially since I receive about 25 shots up my neck, head and face.