question: If the rate of immunization with the vaccine is as high as 85-95% in a society, vulnerable populations who are not vaccinated are also protected. The SARS-CoV-2 pandemic, which caused the COVID-19 disease, continues to spread with new mutations despite all individual and national measures taken. Since there is no effective antiviral drug yet, the most important method of fighting the disease is vaccination. The number of vaccines currently in clinical phase studies is 138 (Phase 1: 36, Phase 2: 65, Phase 3: 31). Bunlar sırasıyla komple viron aşıları (canlı attenüe, inaktif), nükleik asit bazlı DNA ve mRNA aşıları, viral vektör aşıları (replikatif ve nonreplikatif) ve rekombinant protein [protein subunit ve virus like particle (VLP) ] aşılarıdır.