question: Q:A 24-year-old woman comes to the clinic because her period is 4 weeks late, and she is experiencing fatigue and morning nausea. She had her last period almost 8 weeks ago. She is gravida 0 para 0 with previously regular menses and an unremarkable medical history. She had her menarche at the age of 13 years. She has a single sexual partner and does not use contraception. At presentation, her vital signs are within normal limits. Gynecological examination reveals breast and uterine enlargement. There is also cyanosis and softening in the cervical and vaginal regions. Which of the following statements is correct?? 
  {'A': 'The venous congestion in the patient’s reproductive organs is due to the influence of estrogens', 'B': 'Estrone has the largest blood concentration among the estrogens in this patient', 'C': 'Hyperestrogenemia is the most probable cause of this patient’s menstrual delay', 'D': 'In the patient’s condition, blood estrogen level falls dramatically', 'E': 'As the patient’s condition progresses, her estriol levels may rise up to 1000-fold'},