One of my biggest fears is getting cancer one day. Especially when 5-10 percent can come from inherited genes.
Yes, the thought of cancer scares me too, I knew it had a genetic connection, but wasn't sure how much.
(specifically, a caretaker gene), found in all humans; its protein, also called by the synonym breast cancer type 2 susceptibility protein, is responsible for repairing DNA.
BRCA2 and BRCA1 are normally expressed in the cells of breast and other tissue, where they help repair damaged DNA or destroy cells if DNA cannot be repaired. They are involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double strand breaks. If BRCA1 or BRCA2 itself is damaged by a
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Indications.
In 2013 in America alone there were 22,000 cases of ovarian cancer diagnosed and reported. Of these 10% were due to an inherited disorder. It is also the fifth most common cancer related cause of death in women. The BRCA1 and BRCA2 genes are the most common inherited genetic mutations which lead to ovarian cancer. As such a preventative surgery such a prophylactic salpingectomy is thought to decrease this risk of getting cancer. Recent research has shown that ovarian cancer may not originate in the ovaries themselves but start