My uncle suffers from alcoholism. His drinking has resulted in mental and physical health problems.
That is too bad, have you tried to get him to quit?
No, I'm not that close to him. It's not good to drink a lot of alcohol as it can affect the brain, liver, pancreas, and immune system.
I only drink during special occasions.
That's not so bad. As long as you don't drink large amounts over a long time period, have difficulty cutting down, or your usage doesn't lead to social/health problems, you're not an alcoholic. 
Yes, I rarely drink more than one. The only exception is New Years Eve.
That's a good time to drink. A time that isn't good to drink is during pregnancy, as that can cause damage to the baby.
I am a man, so I can't get pregnant. But that makes total sense.
Alcoholism
Alcoholism, also known as alcohol use disorder (AUD), is a broad term for any drinking of alcohol that results in mental or physical health problems. The disorder was previously divided into two types: alcohol abuse and alcohol dependence. In a medical context, alcoholism is said to exist when two or more of the following conditions are present: a person drinks large amounts of alcohol over a long time period, has difficulty cutting down, acquiring and drinking alcohol takes up a great deal of time, alcohol is
strongly desired, usage results in not fulfilling responsibilities, usage results in social problems, usage results in health problems, usage results in risky situations, withdrawal occurs when stopping, and alcohol tolerance has occurred with use. Risky situations include drinking and driving or having unsafe sex, among other things. Alcohol use can affect all parts of the body, but it particularly affects the brain, heart, liver, pancreas and immune system. This can result in mental illness, Wernicke–Korsakoff syndrome, irregular heartbeat, an impaired immune