Do you know anything about the designer Donna Karen?
Yes, I do.  She is an american fasion designer and creator the DKNY clothing labels.  She's quite famous.
Where do they sell her clothing items - in malls or more upscale places?
She sold the company in 2001 to Louis Vuitton Moet Hennessy.  Her clothing was typically found in malls
So does she still design or is she out of the business?
LVMH
LVMH Moët Hennessy – Louis Vuitton SE (), also known as LVMH, is a French multinational luxury goods conglomerate headquartered in Paris. The company was formed in 1987 under the merger of fashion house Louis Vuitton with Moët Hennessy, a company formed after the 1971 merger between the champagne producer Moët & Chandon and Hennessy, the cognac manufacturer. It controls around 60 subsidiaries that each manage a small number of prestigious brands. The subsidiaries are often managed independently. The oldest of the LVMH brands is wine producer Château d'Yquem
Vuitton Moët Hennessy). In 2015 Donna Karan left as chief designer at Donna Karan International, to focus on her Urban Zen brand and Urban Zen Foundation philanthropy. LVMH sold Donna Karan International, with the 'Donna Karan' and 'DKNY' brands, to the G-III Apparel Group in 2016 for $650 million. G-III, based in New York City, is a manufacturer and distributor of clothing and accessories under their owned brands, licensed brands, and private label brands.
Donna Karan New York