text: Orthotricyclen-lo. Not as much estrogen as regular, so no weird mood swings or weight gain. They say you can have break-through bleeding in the middle of the cycle, but I haven't had that problem. However, all estrogen/progestin pills can cause migraines, and I am having them. But I can't prove that's the cause. Also, it's kind of a pain to have to get a prescription, but it's better than yucky condoms.