text: Yes, you should be concerned.\n In those with liver disease or those who take blood thinning medications (such as heart patients) biochemical events cannot lead to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin-\nbasically those with advanced liver disease do not produce enough chemicals to produce clotting.\n a person can bleed to death. \ni wish i could tell you something positive. seek the advice of a doctor asap.\n\ngood luck.