text: I'm guessing that you are aware that anophthalmus is the absence of one or both eyeballs.  At this point, there is no treatment other than taking adaptive measures to compensate for the lack of depth perception (for unilateral cases) or blindness (for bilateral cases).  However, the absence of an eyeball can lead to growth retardation of the facial bones on that side, so surgeons will sometimes implant tissue expanders to promote more normal development and eventually put in a glass prosthesis.