text: Short term mem loss is the biggest thing I believe. Herb smoking hasnt really lead to any other bigger things, like cancer, infections, etc. Although it is a "gateway" drug... Most people who do pot, just do pot. \n\nPersonal experience- Smoked a little one night. Stayed up all night - Smoked a lot the next day - And here I am now... In the questions.... THe worst I can sum things up right now "Everything is nice and slow.... very tired, face is sore."