text: I would definitely not recommend it since Adderall is a stimulant and can cause a panic attack in a panic-prone person.  There are better meds to combine with Zoloft if you have panic problems along with attention problems.  I personally feel that Adderall is too powerful a stimulant to be used in a panic-prone person but I am not a pharmacist (only a psychology graduate student who took psychopharmacology and loved it).  Please ask your doctor or better a pharmacist before taking that combination.  I doubt it would be fatal but it could cause a panic attack and would not likely be helpful in any way.