text: Since  a mature erythrocyte does not contain a nucleus (not a typical eukaryotic cell) , it is commonly referred to as a corpuscle.\nIn sickle cell anemia the cell takes on a sickle shape, does not carry a sufficient amount of oxygen, and may even clog up arterioles and capillaries. This is an inherited disease , more common with black people of African decent. The individual may be a "carrier" in the heterozygous condition, suffering ill effects during exertion or at high altitudes. The full blown disease occurs in the homozygous recessive condition.\nA similar disease, "Coolies anemia" (spelling?) is prevalent among people decending from the Mediterranian area.