text: ASPM is a gene located on human chromosome 1, band q31 (1q31) which is associated with autosomal recessive primary microcephaly (smaller then average sized head).\n"ASPM" is an acronym for "Abnormal Spindle-like, Microcephaly-associated", According to researchers the ASPM gene variation arose about 5,800 years ago, roughly correlating with the development of written language, spread of agriculture and development of cities.