text: All things being equal, the higher the frequency,the more energetic the effect- So, a laser with a frequency in the yellow range, for example, would have less effect than one in the blue range, which has a higher frequency.  The ultimate would likely be an ultraviolet laser, which is very high energy and slightly penetrating as well.  Theoretically, and X-ray laser would be the most devastating, because of the penetration, but as far as I know, that is still a long ways off.