text: I just called the pharmacy I work for to ask the pharmacist on duty..\n\nShe said you should take it with food (or at least something like yogurt or a snack) because it can upset the stomach.\n\nYou should split it up...like take 1 in the morning 1 at night...\n\nAbout taking it with other medications..She said you should take them first and wait about an hour to an hour and 1/2 to take the calcium, not so much because of the calcium absorption, but the medication absorption. She said it can bind with the medication so that you don't get all you should be getting of the Evista, etc.\n\nGood luck!