text: Among the array of substrates that can be altered by CK2 many of them have been found in increased prevalence in cancers of the breast, lung, colon, and prostate. An increased concentration of substrates in cancerous cells infers a likely survival benefit to the cell, and activation of many of these substrates requires CK2. As well the anti-apoptotic function of CK2 allows the cancerous cell to escapes cell death and continue proliferating. Having roles in cell cycle regulation may also indicate CK2's role in allowing cell cycle progression when normally it should have been ceased. This also promotes CK2 as a possible therapeutic target for cancer drugs. When added with other potent anti-cancer therapies, a CK2 inhibitor may increase the effectiveness of the other therapy by allowing drug-induced apoptosis to occur at a normal rate.