text: The Baylis–Hillman reaction is a route for C-C bond formation between an alpha, beta-unsaturated carbonyl and an aldehyde, which requires a nucleophilic catalyst, usually a tertiary amine, for a Michael-type addition and elimination. The stereoselectivity of these reactions is usually poor.  Lanthanum(III)-containing CLAs have been demonstrated to improve stereoselectivity. Similarly, a chiral amine may also be used to achieve stereoselectivity.
  The product obtained by the reaction using the chiral catalyst was obtained in good yield with excellent enantioselectivity.