text: Some catastrophins affect catastrophe by binding to the ends of microtubules and promoting the dissociation of tubulin dimers.
  Different mathematical models of microtubule development are being developed to take into account in vitro and in vivo observations. Meanwhile, there are new in vitro models of microtubule polymerization dynamics, of which catastrophins take a part in, being tested to emulate in vivo behaviors of microtubules.