text: The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon bonds (C-C bonds). This reaction was discovered in 1988 by Tamejiro Hiyama and Yasuo Hatanaka as a method to form carbon-carbon bonds synthetically with chemo- and regioselectivity. The Hiyama coupling has been applied to the synthesis of various natural products. 
  :* : aryl, alkenyl or alkynyl
  :* : aryl, alkenyl, alkynyl or alkyl
  :* : Cl, F or alkyl
  :* : Cl, Br, I or OTf