text: *one ATP by direct phosphorylation of GDP
  *two ATP from oxidation of FADH
  *three ATP at a time for the NADH + H produced within the α-ketoglutarate dehydrogenase reaction, the malate dehydrogenase reaction and the malate decarboxylase reaction.
  <br />
  Due to low glutamate dehydrogenase and glutamate pyruvate transaminase activities, in tumor cells the conversion of glutamate to alpha-ketoglutarate mainly takes place via glutamate oxaloacetate transaminase.