text: The versatility of the Sonogashira reaction makes it a widely used reaction in the synthesis of a variety of compounds. One such pharmaceutical application is in the synthesis of SIB-1508Y, which is more commonly known as Altinicline. Altinicline is a nicotinic acetylcholine receptor agonist that has shown potential in the treatment of Parkinsons disease, Alzheimers disease, Tourette's syndrome, schizophrenia, and attention deficit hyperactivity disorder (ADHD). As of 2008, Altinicline has undergone Phase II clinical trials.
  The Sonogashira cross coupling reaction can be used in the synthesis of imidazopyridine derivatives.