text: The main function of the DREAM complex is to repress G1/S and G2/M gene expression during quiescence (G). Entry into the cell cycle dissociates p130 from the complex and leads to subsequent recruitment of activating E2F proteins. This allows for the expression of E2F regulated late G1 and S phase genes. BMYB (MYBL2), which is repressed by the DREAM complex during G is also able to be expressed at this time, and binds to MuvB during S phase to promote the expression of key G/M phase genes such as CDK1 and CCNB1. FOXM1 is then recruited in G to further promote gene expression (e.g. AURKA). During late S phase BMYB is degraded via CUL1 (SCF complex), while FOXM1 is degraded during mitosis by the APC/C. Near the end of the cell cycle, the DREAM complex is re-assembled by DYRK1A to repress G1/S and G2/M genes.