text: The gauche effect is very sensitive to solvent effects, due to the large difference in polarity between the two conformers. For example, 2,3-dinitro-2,3-dimethylbutane, which in the solid state exists only in the gauche conformation, prefers the gauche conformer in benzene solution by a ratio of 79:21, but in carbon tetrachloride, it prefers the anti conformer by a ratio of 58:42. Another case is trans-1,2 difluorocyclohexane, which has a larger preference for the di-equatorial conformer, rather than the anti-diaxial conformer, in more polar solvents.