text: As the ordinate scale spans the entire range of theoretically possible  vales, from  to  one can see at a glance at an Eadie–Hofstee plot how well the experimental design fills the theoretical design space, and the plot makes it impossible to hide poor design. By contrast, the other well known straight-line plots make it easy to choose scales that suggest that the design is better than it is. Faulty design, as shown in the right-hand diagram, is common with experiments with a substrate that is not soluble enough or too expensive to use concentrations above , and in this case  cannot be estimated satisfactorily. The opposite case, with  values concentrated above  (left-hand diagram) is less common but not unknown, as for example in a study of nitrate reductase.