text: In biological systems, phosphorus can be found as free phosphate anions in solution (inorganic phosphate) or bound to organic molecules as various organophosphates.
  Inorganic phosphate is generally denoted P and at physiological (homeostatic) pH primarily consists of a mixture of  and  ions. At a neutral pH, as in the cytosol (pH = 7.0), the concentrations of the orthophoshoric acid and its three anions have the ratios
  Thus, only  and  ions are present in significant amounts in the cytosol (62% , 38% ). In extracellular fluid (pH = 7.4), this proportion is inverted (61% , 39% ).
  Inorganic phosphate can also be present as pyrophosphate anions , which give orthophosphate by hydrolysis:
  : + HO  2 
  Organic phosphates are commonly found in the form of esters as nucleotides (e.g. AMP, ADP, and ATP) and in DNA and RNA. Free orthophosphate anions can be released by the hydrolysis of the phosphoanhydride bonds in ATP or ADP. These phosphorylation and dephosphorylation reactions are the immediate storage and source of energy for many metabolic processes. ATP and ADP are often referred to as high-energy phosphates, as are the phosphagens in muscle tissue.  Similar reactions exist for the other nucleoside diphosphates and triphosphates.