text: Pdr1p (Pleiotropic Drug Resistance 1p)  is a transcription factor found in yeast and is a key regulator of genes involved in general drug response. It induces the expression of ATP-binding cassette transporter, which can export toxic substances out of the cell, allowing cells to survive under general toxic chemicals.  It binds to DNA sequences that contain certain motifs called pleiotropic drug response element (PDRE). Pdr1p is encoded by a gene called PDR1 (also known as YGL013C) on chromosome VII.