text: DNA is a major example of a supramolecular polymer. protein Much effort has been develoted to related but synthetic materials. At the same time, their reversible and dynamic nature make supramolecular polymers bio-degradable, which surmounts hard-to-degrade issue of covalent polymers and makes supramolecular polymers a promising platform for biomedical applications. Being able to degrade in biological environment lowers potential toxicity of polymers to a great extent and therefore, enhances biocompatibility of supramolecular polymers.