text: Conducting clinical trials of vaccines during epidemics and pandemics is subject to ethical concerns. For diseases with high mortality rates like Ebola, assigning individuals to a placebo or control group can be viewed as a death sentence. In response to ethical concerns regarding clinical research during epidemics, the National Academy of Medicine authored a report identifying seven ethical and scientific considerations. These considerations are:
  * Scientific value
  * Social value
  * Respect for persons
  * Community engagement
  * Concern for participant welfare and interests
  * A balance towards benefit over risks
  * Post-trial access to tested therapies that had been withheld during the trial