text: The plant sorghum is well established model organism and can adapt in hot and dry environments. For this reason, it is used as a model to study calmodulins role in plants. Sorghum contains seedlings that express a glycine-rich RNA-binding protein, SbGRBP. This particular protein can be modulated by using heat as a stressor. Its unique location in the cell nucleus and cytosol demonstrates interaction with calmodulin that requires the use of Ca. By exposing the plant to versatile stress conditions, it can cause different proteins that enable the plant cells to tolerate environmental changes to become repressed. These modulated stress proteins are shown to interact with CaM. The CaMBP' genes expressed in the sorghum are depicted as a “model crop” for researching the tolerance to heat and drought stress.