text: Asymmetric ester hydrolysis with pig liver esterase is the enantioselective conversion of an ester to a carboxylic acid through the action of the enzyme pig liver esterase (EC 3.1.1.1). Asymmetric ester hydrolysis involves the selective reaction of one of a pair of either enantiotopic (within the same molecule and related by a symmetry plane of the molecule) or enantiomorphic (in enantiomeric molecules and related as mirror images) ester groups.