text: See also: Dihydroxylation
  In a vicinal diol, the two hydroxyl groups occupy vicinal positions, that is, they are attached to adjacent atoms. These compounds are called glycols. Examples include ethane-1,2-diol or  ethylene glycol HO−(CH)−OH, a common ingredient of antifreeze products. Another example is propane-1,2-diol, or alpha propylene glycol, HO−CH−CH(OH)−CH, used in the food and medicine industry, as well as a relatively non-poisonous antifreeze product.
  On commercial scales, the main route to vicinal diols is the hydrolysis of epoxides. The epoxides are prepared by epoxidation of the alkene. An example in the synthesis of trans-cyclohexanediol or by microreactor:
  For academic research and pharmaceutical areas, vicinal diols are often produced from the oxidation of alkenes, usually with dilute acidic potassium permanganate or Osmium tetroxide. Osmium tetroxide can similarly be used to oxidize alkenes to vicinal diols. The chemical reaction called Sharpless asymmetric dihydroxylation can be used to produce chiral diols from alkenes using an osmate reagent and a chiral catalyst. Another method is the Woodward cis-hydroxylation (cis diol) and the related Prévost reaction (anti diol), which both use iodine and the silver salt of a carboxylic acid.
  Other routes to vic-diols are the hydrogenation of acyloins and the pinacol coupling reaction.