text: The adducts formed by the addition of ammonia to aldehydes have long been studied.  Compounds containing both a primary amino group and a hydroxyl group bonded to the same carbon atom are rarely stable, as they tend to dehydrate to form imines which polymerise to hexamethylenetetramine. A rare stable example is the adduct of ammonia and hexafluoroacetone, .
  The C-substituted derivatives are obtained by reaction of aldehydes and ammonia: