text: Cholinergic crisis, sometimes known by the mnemonic "SLUDGE syndrome" (Salivation, Lacrimation, Urination, Defecation, Gastrointestinal distress and Emesis), can be a consequence of:
  * Contamination with - or excessive exposure to - certain chemicals including:
  **nerve agents, (e.g., sarin, VX, Novichok agents).
  **organophosphorus insecticides (e.g., parathion, aldicarb)
  **nicotine poisoning can be thought of as a subset of cholinergic crisis, as it also involves excessive parasympathetic stimulation.
  * Ingestion of certain poisonous fungi (particularly the muscarine-containing members of the genera Inocybe and Clitocybe).
  *In medicine, this is seen in patients with myasthenia gravis who take too high a dose of medications such as cholinesterase inhibitors, or seen following general anaesthesia, when too high a dose of a cholinesterase inhibitor drug is given to reverse surgical muscle paralysis.