text: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans.
  This gene encodes an inositol polyphosphate 5-phosphatase.  The responsible gene locus is at Xq26.1. This phosphatase enzyme is in part responsible for regulating membrane trafficking actin polymerization, and is located in several subcellular parts of the trans-Golgi network.
  Deficiencies in OCRL-1 may cause with oculocerebrorenal syndrome and also have been linked to Dent's disease.