text: The word proteomics was first used in 1994 by Marc Wilkins as the study of “the protein equivalent of a genome”. It is defined as all of the proteins expressed in a biological system under specific physiologic conditions at a certain point in time.  It can change with any biochemical alteration, and so it can only be defined under certain conditions.  Neuroproteomics is a subset of this field dealing with the complexities and multi-system origin of neurological disease.  Neurological function is based on the interactions of many proteins of different origin, and so requires a systematic study of subsystems within its proteomic structure.