text: As found by Brooks, et al., while lactate is disposed of mainly through oxidation and only a minor fraction supports gluconeogenesis, lactate is the main gluconeogenic precursor during sustained exercise.
  Brooks demonstrated in his earlier studies that little difference in lactate production rates were seen in trained and untrained subjects at equivalent power outputs.  What was seen, however, was more efficient clearance rates of lactate in the trained subjects suggesting an upregulation of MCT protein.
  Local lactate use depends on exercise exertion.  During rest, approximately 50% of lactate disposal take place through lactate oxidation whereas in time of strenuous exercise (50-75% VO2 max) approximately 75-80% of lactate is used by the active cell, indicating lactate’s role as a major contributor to energy conversion during increased exercise exertion.