text: LiHMDS is often used in organic chemistry as a strong non-nucleophilic base. Its conjugate acid has a pK of ~26, making it is less basic than other lithium bases, such as LDA (pK of conjugate acid ~36). It is relatively more sterically hindered and hence less nucleophilic than other lithium bases. It can be used to form various organolithium compounds, including acetylides or lithium enolates.
  where Me = . As such, it finds use in a range of coupling reactions, particularly carbon-carbon bond forming reactions such as the Fráter–Seebach alkylation and mixed Claisen condensations.
  An alternative synthesis of tetrasulfur tetranitride entails the use of  as a precursor with pre-formed S&ndash;N bonds.  is prepared by the reaction of lithium bis(trimethylsilyl)amide and sulfur dichloride ().
  The  reacts with the combination of  and sulfuryl chloride () to form , trimethylsilyl chloride, and sulfur dioxide: