There are two things making people crazy in a bad way - the economy and the politics.
More people than ever who have irrational fears? Want to reduce ill will, madness, and that queasy feeling your supervisor is out to lay you off and send your job to China? 
Make the economic system and the political system more honest, compassionate and user friendly.

Feeling under the weather? Make our weather great again. Fight climate change.

Are there more people than ever who can't tell real reality from fake reality? Make the media start telling the truth, the whole truth and nothing but the truth.

And, by the way, just because you're not paranoid doesn't mean the CIA isn't out to do you in.

Then we round up all the psychiatrists and make them wear clown outfits with huge oversized shoes so they can't get away.

Then change all drug stores into pot dispensaries. Finally, disband Big Pharma, take their trillions of dollars and give it to the poor.
   There you go.  I feel cheerful already.