It would be informative to see research about the effects of prohibition on substance abuse in towns and villages. I have had students in villages ask me whether pot or methamphetamine is safer and that they lean toward trying meth because it is the easiest substance to acquire and they want to experiment (alcohol being more expensive than either of these). In other villages, gas huffing has caused terrible ripple effects because it is easily accessible and very cheap. 
Prohibition seems like a great option when you ignore the reality of black markets and the underlying problem of the attraction to substance abuse in ALL western communities. Is there a corporation interested/doing this research?