Mitral valve regurgitation is often mild and progresses slowly. Some people with mitral valve regurgitation might not have symptoms for many years. But sometimes, mitral valve regurgitation develops quickly. This condition, called acute mitral valve regurgitation, causes sudden signs and symptoms. Fatigue is a common but nonspecific symptom of mitral valve regurgitation. Other signs and symptoms of mitral valve regurgitation include:  Sound of blood flow across the valve (heart murmur) Irregular heartbeat (arrhythmia) Shortness of breath (dyspnea), especially when lying down Sensation of a rapid, pounding or fluttering heartbeat (palpitations) Swollen feet or ankles (edema) 
mitral valve regurgitation mild progresses slowly  people mitral valve regurgitation symptoms years  sometimes  mitral valve regurgitation develops quickly  condition  called acute mitral valve regurgitation  causes sudden signs symptoms  fatigue common nonspecific symptom mitral valve regurgitation  signs symptoms mitral valve regurgitation include:  sound blood flow across valve (heart murmur) irregular heartbeat (arrhythmia) shortness breath (dyspnea)  especially lying down sensation rapid  pounding fluttering heartbeat (palpitations) swollen feet ankles (edema) 
mitral valve regurgitation