 Signs and symptoms of familial Mediterranean fever usually begin during childhood. They occur in bouts called attacks that last 1-3 days. Arthritic attacks may last for weeks or months. Signs and symptoms of FMF attacks vary, but can include: FMF  Fever Abdominal pain Chest pain, which can make it hard to breathe deeply Painful, swollen joints, usually in the knees, ankles and hips A red rash on your legs, especially below your knees Muscle aches A swollen, tender scrotum  The attacks generally resolve spontaneously after a few days. Between attacks, you'll likely feel back to your typical health. Symptom-free periods may be as short as a few days or as long as several years. In some people, the first sign of FMF is amyloidosis. With amyloidosis, the protein amyloid A, which is not typically found in the body, builds up in organs ⸺ especially the kidneys ⸺ causing inflammation and interfering with their function.
 signs symptoms familial mediterranean fever begin childhood  occur bouts called attacks last 1-3 days  arthritic attacks may last weeks months  signs symptoms fmf attacks vary  can include: fmf  fever abdominal pain chest pain  can hard breathe deeply painful  swollen joints  knees  ankles hips red rash legs  especially knees muscle aches swollen  tender scrotum  attacks generally resolve spontaneously days  attacks  you'll likely feel back typical health  symptom-free periods may short days long years  people  first sign fmf amyloidosis  amyloidosis  protein amyloid a  typically found body  builds organs ⸺ especially kidneys ⸺ causing inflammation interfering function
familial mediterranean fever