Babies with XLA generally appear healthy for the first few months because they're protected by the antibodies they got from their mothers before birth. When these antibodies clear from their systems, the babies begin to develop often severe, recurrent bacterial infections — such as of the ears, lungs, sinuses and skin — that can be life-threating. XLA Male infants born with XLA have: XLA  Very small tonsils Small or no lymph nodes  Causes            X-linked inheritance pattern with carrier mother       Open pop-up dialog box          Close    X-linked inheritance pattern with carrier mother   X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier.               X-linked inheritance pattern with carrier mother       Open pop-up dialog box           X-linked inheritance pattern with carrier mother       Open pop-up dialog box  Open pop-up dialog box       Close    X-linked inheritance pattern with carrier mother   X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier.          Close    X-linked inheritance pattern with carrier mother   X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier.        Close    X-linked inheritance pattern with carrier mother   X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier.     Close    Close  Close X-linked inheritance pattern with carrier mother   X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier.  X-linked inheritance pattern with carrier mother Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier. Women can pass down X-linked recessive disorders such as X-linked agammaglobulinemia. A woman who is a carrier of an X-linked recessive disorder has a 25% chance of having an unaffected son, a 25% chance of having an affected son, a 25% chance of having an unaffected daughter and a 25% chance of having a daughter who also is a carrier. X-linked agammaglobulinemia is caused by a genetic mutation. People with the condition can't produce antibodies that fight infection. About 40% of people with the condition have a family member who has it. Complications People with XLA can live relatively normal lives and should be encouraged to participate in regular activities for their ages. However, recurrent infections related to XLA will likely require careful attention and aggressive treatment. They can cause organ damage and be life-threatening. XLA XLA Possible complications include:  Chronic lung disease Increased risk of certain cancers Infectious arthritis Increased risk of central nervous system infections from live vaccines                   By Mayo Clinic Staff By Mayo Clinic Staff  X-linked agammaglobulinemia care at Mayo Clinic 
babies xla generally healthy first months they're protected antibodies mothers birth  antibodies clear systems  babies begin develop severe  recurrent bacterial infections — ears  lungs  sinuses skin — can life-threating  xla male infants born xla have: xla  small tonsils small lymph nodes  causes            x-linked inheritance pattern carrier mother       open pop-up dialog box          close    x-linked inheritance pattern carrier mother   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier                x-linked inheritance pattern carrier mother       open pop-up dialog box           x-linked inheritance pattern carrier mother       open pop-up dialog box  open pop-up dialog box       close    x-linked inheritance pattern carrier mother   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier           close    x-linked inheritance pattern carrier mother   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier         close    x-linked inheritance pattern carrier mother   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier      close    close  close x-linked inheritance pattern carrier mother   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier   x-linked inheritance pattern carrier mother women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier  women can pass down x-linked recessive disorders x-linked agammaglobulinemia  woman who carrier x-linked recessive disorder 25% chance unaffected son  25% chance affected son  25% chance unaffected daughter 25% chance daughter who carrier  x-linked agammaglobulinemia caused genetic mutation  people condition can't produce antibodies fight infection  40% people condition family member who it  complications people xla can live normal lives encouraged participate regular activities ages  however  recurrent infections xla will likely require careful attention aggressive treatment  can cause organ damage life-threatening  xla xla possible complications include:  chronic lung disease increased risk cancers infectious arthritis increased risk central nervous system infections live vaccines                   mayo clinic staff mayo clinic staff  x-linked agammaglobulinemia care mayo clinic 
x linked agammaglobulinemia