Angelman syndrome signs and symptoms include:  Developmental delays, including no crawling or babbling at 6 to 12 months Intellectual disability No speech or minimal speech Difficulty walking, moving or balancing well Frequent smiling and laughter Happy, excitable personality Sucking or feeding difficulty Trouble going to sleep and staying asleep  People who have Angelman syndrome may also show the following features:  Seizures, usually beginning between 2 and 3 years of age Stiff or jerky movements Small head size, with flatness in the back of the head Tongue thrusting Hair, skin and eyes that are light in color Unusual behaviors, such as hand flapping and arms uplifted while walking Sleep problems Curved spine (scoliosis) 
angelman syndrome signs symptoms include:  developmental delays  including crawling babbling 6 12 months intellectual disability speech minimal speech difficulty walking  moving balancing well frequent smiling laughter happy  excitable personality sucking feeding difficulty trouble going sleep staying asleep  people who angelman syndrome may show following features:  seizures  beginning 2 3 years age stiff jerky movements small head size  flatness back head tongue thrusting hair  skin eyes light color unusual behaviors  hand flapping arms uplifted walking sleep problems curved spine (scoliosis) 
angelman syndrome