Investing, Biotechnology, Venture Capital, Science, Immune System.
strategies for taming cytokine pleiotropy (the ability to affect multiple cell types) through protein engineering. IL-2 signals through the dimeric IL-2Rβγ or trimeric IL-2Rαβγ receptor complexes, with the IL-2Rα (CD25) subunit being constitutively expressed on regulatory T cells (Tregs). A