Neurodegenerative Disease, Neuroscience, Translational Research, Neurobiology, Pathology.
misfolded TAR DNA-binding protein 43 (TDP-43) are characteristic of FTLD-TDP and ALS. In her 2018 paper, Lee demonstrated the cell-to-cell transmission of TDP-43 in mice for the first time. In fact, this groundbreaking study showed that injecting human-derived abnormal TDP-43 into mice brain