Molecular Biology, Oncology, Research, Cell Signalling, Medical.
(PLC-γ-PKC-MAPK) pathway, which is the pathway of interest that will be explained in this section (4). In this system, the VEGF-A molecule binds to and dimerizes VEGFR-1 and VEGFR-2, and signal transduction networks initiated by the VEGF-A/VEGFR2 complex promote angiogenesis, vascular permeability,