Genetics, Covid-19, Vaccines, Research, Dna.
with dCas12a and gRNAs harbouring a single spacer complementary to promoters in front crt genes. © Cell pellet obtained after growing transformants of strain CAR-041 with (left panel) gRNAs used in singleplex downregulation for targeting crtI, crtE and crtYB. For comparison transformants with