Cancer, Cancer Treatments, Biotechnology, Treatment, Science.
mice that were selectively depleted of dLN migratory dendritic cells (migDCs) and treated them with anti-PD-L1 and anti-CD4 antibodies. Upon examining the dLN-tumor OL clones, they noted that ICIs enhanced the priming of polyclonal tumor-reactive T-cells by migDCs in the dLN, resulting in clonal