Neurodegenerative Disease, Neuroscience, Translational Research, Neurobiology, Pathology.
amyotrophic lateral sclerosis (ALS) is the presence of misfolded protein deposits in the brain, giving them the collective term ‘proteinopathies’. But what causes these proteins to aggregate and how do they propagate through the brain? Pioneering studies by Lee and colleagues in 2014 and 2015