Investing, Biotechnology, Venture Capital, Science, Immune System.
extend their half-life (t1/2) and area under the curve (AUC). This can be achieved through half-life extension (HLE) techniques, such as: 1. Fusion to polymers 2. Albumin fusions 3. Antibody Fc domains (often made monovalent through knob-in-hole mutations) By extending the half-life of cytokines,