Molecular Biology, Genetics, Genomics, Biology, Disease.
debilitating neurodegenerative condition, AD is characterized by hallmark protein aggregates: Amyloid-beta (Aβ) Plaques: Derivatives of aberrant APP cleavage, exacerbated by mutations in genes such as APP, PSEN1, or PSEN2. Tau Neurofibrillary Tangles: Resulting from hyperphosphorylation events