Cancer, Research, Nobel Prize, Immune System, Physiology.
(Yervoy®). Honjo discovered another immune blocking protein called programmed cell death protein-1 (PD-1). FDA-approved therapies that target PD-1 Include pembrolizumab (Keytruda®) and nivolumab (Opdivo®). While this particular approach to immunotherapy got its start in the solid tumors, the