Molecular Dynamics, Protein Folding, Alphafold.
Steinegger, co-author of the ColabFold paper who led the development of MMSeqs2, using MMSeqs2 can decrease the time to build MSAs from hours to minutes with the the paper claiming a speedup up of 40 to 60 times. The key to MSA speedups is a novel strategy of pre-filtering with a k-mer search (a