Molecular Biology, Oncology, Research, Cell Signalling, Medical.
as well as endothelial cell survival, migration, and proliferation (1,3,5). The dimerization of VEGFR-1 and VEGFR-2 as well as the transphosphorylation between the receptors’ intracellular kinase domains is followed by the activation of the VEGF Receptor Tyrosine Kinase (RTK) which induces the