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Home > A Level and IB > Psychology > Psychology - Genetic explanations of schizophrenia
Psychology - Genetic explanations of schizophreniaPowerpoint Presentation 90.32 Kb

 Genetic explanations of
schizophrenia…read more
 Family studies
To investigate the transmission of
schizophrenia, studies compare rates of
schizophrenia is relatives of diagnosed
cases in relatives of controls.
First degree relatives share an average of
50% of their genes and second degree
relatives share an average of 25% of their
Therefore, if there is genetic transmission
involved in schizophrenia, we would expect
that the closer the biological relationship,
the greater the risk of developing
schizophrenia.…read more
 Kendler et al found a risk of 3.7% in first
degree relatives of people with
schizophrenia, as compared to a lifetime
risk in a normal control group of only
0.2%…read more
 The Copenhagen High-Risk
Study ­ Kety et al
A prospective, longitudinal study carried
out in Denmark beginning in 1962.
Kety et al identified 207 offspring of
mothers diagnosed with schizophrenia
(high-risk group) along with a matched
control of 104 children with healthy
mothers (low-risk group).
The children were matched on key
variables including age, gender and
parental socio-economical status…read more
 Schizophrenia was diagnosed in 16.2%
of the high-risk group compared with
1.9% in the low-risk group.
There was also a greater rate of
schizotypal personality disorder in the
high-risk group.
This seems to provide good evidence for
a genetic influence.…read more
 Evaluation of Kety et al
Advantage of a longitudinal prospective
study ­ does not rely on retrospective
data. The study was conducted over
several years ­ important because
schizophrenia can develop at any point
in an individual's life.
Children were matched on relevant
variables which is important because
factors such as socio-economic status
are known to be a risk factor in…read more
 




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