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Musculoskeletal System - Cartilage Development

From Embryology Fetal head (week 12)

The mesoderm forms nearly all the connective tissues of the musculoskeletal system. Each tissue (cartilage, bone, and muscle) goes through many different mechanisms of differentiation. Recent studies[1] show that Sox9 acts as a key regulator of early chondrocyte differentiation.

Some Recent Findings



Development Overview

Mesoderm Development

Somite Development

Limb Development



Masaharu Takigawa CCN2: a master regulator of the genesis of bone and cartilage. J Cell Commun Signal: 2013, 7(3);191-201 PubMed 23794334

| MC3709051 | J Cell Commun Signal. Yasuhiko Kawakami, Joaquín Rodriguez-León, Juan Carlos Izpisúa Belmonte The role of TGFbetas and Sox9 during limb chondrogenesis. Curr. Opin. Cell Biol.: 2006, 18(6);723-9 PubMed 17049221

Mary B Goldring, Kaneyuki Tsuchimochi, Kosei Ijiri The control of chondrogenesis. J. Cell. Biochem.: 2006, 97(1);33-44 PubMed 16215986

Lillian Shum, Glen Nuckolls The life cycle of chondrocytes in the developing skeleton. Arthritis Res.: 2002, 4(2);94-106 PubMed 11879545


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Search Pubmed: Cartilage Development | chondroblast Development | chondroclast Development



Glossary Links

Cite this page: Hill, M.A. 2017 Embryology Musculoskeletal System - Cartilage Development. Retrieved October 24, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Musculoskeletal_System_-_Cartilage_Development

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