[null, {"document_url": "https://rd.springer.com/chapter/10.1007/978-1-4899-7146-3_4", "unformatted_src": "https://media.springernature.com/w306/springer-static/cover/book/978-1-4899-7146-3.jpg", "src": "https://media.springernature.com/w306/springer-static/cover/book/978-1-4899-7146-3.jpg"}, null]


Profound Retardation and Multiple Impairment Profound Retardation and Multiple Impairment pp 54-67 | Cite as

Prader — Willi Syndrome



Prader—Willi Syndrome (PWS) was first described in 1956 by Swiss doctors, Andrea Prader, Heinrich Willi and Alexis Labhart, as a result of their observations of five male and four female patients, who ranged in age from 5 to 23 years old. They described the syndrome as a ‘not infrequent, clearly defined, unique clinical syndrome’ (Prader, Labhart and Willi, 1956). PWS was independently first described in England by Dr B.M. Laurance (1961, 1967), and later by Professor V. Dubowitz (1969). The main features of the syndrome are:


Temper Tantrum Calorific Requirement Willi Syndrome Mental Retar High Pain Threshold





© Springer Science+Business Media Dordrecht 1987




Waters J. (1987) Prader — Willi Syndrome. In: Profound Retardation and Multiple Impairment. Springer, Boston, MA



