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Cicatricial pemphigoid | definition of cicatricial pemphigoid by Medical dictionary

cicatricial pemphigoid

Related to cicatricial pemphigoid: Ocular Cicatricial Pemphigoid


Etymology: L, cicatrix, scar; Gk, pemphix, blister or bubble + eidos, form
a benign, chronic, usually bilateral, subepidermal blistering disease chiefly involving the mucous membranes, especially those of the mouth and eye. It heals by scarring and may lead to slow shrinkage of the affected tissues, and to blindness if untreated. Also called benign mucosal pemphigoid. Cicatricial pemphigoid

cic·a·tri·cial pem·phi·goid

(sik'ă-trish'ăl pem'fi-goyd)
A chronic disease that produces adhesions and progressive cicatrization and shrinkage of the conjunctival, oral, and vaginal mucous membranes.

pemphigoid, cicatricialÂ

A rare, idiopathic, chronic systemic disease, most commonly of the elderly and characterized by recurrent blisters and bullae of the skin and mucous membranes, with subsequent scarring and shrinkage. The disease may affect only the conjunctiva (ocular pemphigoid). In this case, the clinical picture is a conjunctivitis with hyperaemia, mucous discharge and small vesicles, which on bursting result in ulceration, pseudomembranes, conjunctival subepithelial fibrosis and conjunctival shrinkage. The disease may give rise to adhesion between the palpebral and bulbar conjunctiva (symblepharon), ankyloblepharon, xerophthalmia, keratoconjunctivitis sicca, entropion, trichiasis and dry eye with corneal ulcer. There is pain or irritation and blurred vision. Treatment includes corticosteroids, surgery for entropion and trichiasis, and keratoprosthesis if vision is affected. Syn. benign mucous pemphigoid. See pseudomembranous conjunctivitis; Stevens-Johnson syndrome; ocular ferning test.

be·nign mu·cous mem·brane pem·phi·goid

(bĕ-nin myūkŭs membrān pemfi-goyd)
Blistering disease chiefly involving the subepidermal mucous membranes of mouth and eye (ocular pemphigus); usually chronic, benign, and typically bilateral. Scarring can occur and may lead to progressive shrinkage and tightening of the affected mucous membranes and connective tissues.
Synonym(s): cicatricial pemphigoid, ocular cicatricial pemphigoid.

cicatricial pemphigoid (sikətrishəl pem´figoid´),

n See pemphigoid, benign mucous membrane.


1. resembling pemphigus.
2. a group of skin disorders similar to but clearly distinguishable from pemphigus.
bullous pemphigoid
an autoimmune disease of skin and oral mucosa with vesicles, bullae and ulcerations; occurs rarely in dogs and humans.
a form that involves the oral and ocular mucosa.


Pure ocular cicatricial pemphigoid is a unique clinical and immunopathological entity distinct from bullous pemphigoid and other subsets identified by antigenic specificity of autoantibodies," Archives of Dermatology, vol.
Mucous Membrane Pemphigoid with Tracheal Involvement
Kirtschig G, Marinkovich MP, Burgeson RE, Yancey KB: Anti-basement membrane autoantibodies in patients with anti-epilegrin cicatricial pemphigoid bind the alpha subunit of laminin subunit of laminin 5.
The etiopathogenesis of autoimmune bullous diseases/Otoimmun bulloz hastaliklarin etyopatogenezi
Topical tacrolimus for oral cicatricial pemphigoid.
A systematic review of management of oral lichen planus
Ahmed AR, Kurgis BS, Rogers RS 3rd: Cicatricial pemphigoid.
The clinical diagnosis of autoimmune bullous diseases/Otoimmun bulloz hastaliklarin klinik tanisi
The differential diagnosis included Behcet's disease, cicatricial pemphigoid, a fixed drug reaction, and allergic contact dermatitis.
Tongue erosions and diet cola
She said it does not scar except in vulvovaginal areas, where it can lead to disfigurements similar to cicatricial pemphigoid.
Lichen planus and beyond: a review of erosive noninfectious skin diseases
Patients with cicatricial pemphigoid or mucous membrane pemphigoid have benefited from IVIg.
IVIg gains second-line utility for skin diseases: inflammatory, autoimmune diseases
In yet another group of patients, mucin deficiency due to Stevens-Johnson syndrome or ocular cicatricial pemphigoid is the underlying mechanism of dry eye.
Dry eye in present scenario
Sacher C, Hunzelmann N: Cicatricial pemphigoid (mucous membrane pemphigoid): current and emerging therapeutic approaches.
Treatment of subepidermal autoimmune bullous diseases/Subepidermal otoimmun bulloz hastaliklarin tedavisi
The common condition was cicatricial pemphigoid, which is a nonspecific skin disease that can affect mucous membranes in the eyes, mouth, vagina, and vulva.
Skin disorders common cause of vulvovaginal symptoms, expert says
Cicatricial pemphigoid is a vesiculobullous disease of the skin that may be found in the oral cavity.
Oral cicatricial pemphigoid
These include pemphigus vulgaris (PV),pemphigus foliaceous (PF), pemphigus herpetiformis, bullous pemphigoid (BP),linear bullous dermatosis (LAD), cicatricial pemphigoid (CP), epidermolysis bullosa acquisita(psoriasis bullosa acquisita) and a novel bullous dermatosis targeting 200kDa molecule present in the lower lamina lucida.
Coexistence of psoriasis with bullous pemphigoid: a case report