Small studies have shown adequate concordance of MRI findings with CT in established cases of DLD utilizing a variety of specialized MRI sequences. Some MRI sequences in the setting of DLD may provide additional functional information such as tissue characterization, gas transfer efficiency, and lung elasticity [106- 118]. Diffuse Lung Disease chest radiograph at time of initial diagnosis of DLD may assist with diagnosis of these other conditions via radiograph on follow-up. FDG-PET/CT Skull Base to Mid-Thigh There is limited research supporting the use of FDG-PET/CT in some DLDs, which does not currently support FDG-PET/CT for imaging of acute exacerbation or acute deterioration of DLD. MRI Chest There is limited research supporting the use of MRI in some DLDs, none of which currently supports the use of MRI for imaging of acute exacerbation or acute deterioration of DLD. FDG-PET/CT Skull Base to Mid-Thigh There is limited research supporting the use of FDG-PET/CT in DLDs. In sarcoidosis, FDG-PET/CT can be used as a marker of disease extent and severity, and it can assist in follow-up and monitoring of treatment response [86,87,89,92,93,95,96,98-100]. Research supporting the use of FDG-PET/CT is more limited in other DLDs but has been evaluated in some studies of lung fibrosis [90,91,102]. Diffuse Lung Disease MRI Chest There is limited research supporting the use of MRI in DLD, none of which currently supports the use of MRI for follow-up imaging. Small studies have shown adequate concordance of MRI findings with CT in established cases of DLD utilizing a variety of specialized MRI sequences. Some MRI sequences in the setting of DLD may provide additional functional information such as tissue characterization, gas transfer efficiency, and lung elasticity. [106- 118]. Radiography Chest There is no research supporting the use of chest radiography over CT for follow-up imaging of confirmed DLD without acute clinical deterioration.
Diffuse Lung Disease. Small studies have shown adequate concordance of MRI findings with CT in established cases of DLD utilizing a variety of specialized MRI sequences. Some MRI sequences in the setting of DLD may provide additional functional information such as tissue characterization, gas transfer efficiency, and lung elasticity [106- 118]. Diffuse Lung Disease chest radiograph at time of initial diagnosis of DLD may assist with diagnosis of these other conditions via radiograph on follow-up. FDG-PET/CT Skull Base to Mid-Thigh There is limited research supporting the use of FDG-PET/CT in some DLDs, which does not currently support FDG-PET/CT for imaging of acute exacerbation or acute deterioration of DLD. MRI Chest There is limited research supporting the use of MRI in some DLDs, none of which currently supports the use of MRI for imaging of acute exacerbation or acute deterioration of DLD. FDG-PET/CT Skull Base to Mid-Thigh There is limited research supporting the use of FDG-PET/CT in DLDs. In sarcoidosis, FDG-PET/CT can be used as a marker of disease extent and severity, and it can assist in follow-up and monitoring of treatment response [86,87,89,92,93,95,96,98-100]. Research supporting the use of FDG-PET/CT is more limited in other DLDs but has been evaluated in some studies of lung fibrosis [90,91,102]. Diffuse Lung Disease MRI Chest There is limited research supporting the use of MRI in DLD, none of which currently supports the use of MRI for follow-up imaging. Small studies have shown adequate concordance of MRI findings with CT in established cases of DLD utilizing a variety of specialized MRI sequences. Some MRI sequences in the setting of DLD may provide additional functional information such as tissue characterization, gas transfer efficiency, and lung elasticity. [106- 118]. Radiography Chest There is no research supporting the use of chest radiography over CT for follow-up imaging of confirmed DLD without acute clinical deterioration.