Mutations in the Reelin signaling pathway are one of the autosomal recessive nonprogressive congenital ataxias with marked cerebellar and vermian hypoplasia and gyral simplification [4]. Developmental causes of nonprogressive congenital ataxia include posterior fossa malformations, such as rhombencephalosynapsis, Dandy-Walker syndrome, and Chiari II malformations [4]. Acquired causes of nonprogressive congenital ataxia include prenatally acquired cerebellar injury such as congenital cytomegalovirus infection, in utero cerebellar stroke, and perinatal disrupted development of the cerebellum as can be seen in premature infants and those with perinatal ischemic injury [51]. In the setting of chronic nonprogressive ataxia, imaging can be helpful in identifying the presence of congenital cerebellar, vermian, brainstem, and supratentorial brain malformations and acquired cerebellar disruptions due to prenatal or perinatal insult, although imaging can be normal in genetic etiologies [1,4,25,40]. CT Head Although CT may provide an assessment of major structural abnormalities in the posterior fossa, CT is less sensitive than MRI for assessment of intracranial structures [14,28]. The use of IV contrast is generally not warranted in assessment of brain structural abnormalities that present with chronic nonprogressive ataxia in children. Ataxia-Child CT Complete Spine There is no relevant literature to support the use of CT complete spine in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Head and Neck There is no relevant literature to support the use of CTA head and neck in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Head There is no relevant literature to support the use of CTA head in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Neck There is no relevant literature to support the use of CTA neck in the initial evaluation of a child with chronic nonprogressive ataxia.
Ataxia Child. Mutations in the Reelin signaling pathway are one of the autosomal recessive nonprogressive congenital ataxias with marked cerebellar and vermian hypoplasia and gyral simplification [4]. Developmental causes of nonprogressive congenital ataxia include posterior fossa malformations, such as rhombencephalosynapsis, Dandy-Walker syndrome, and Chiari II malformations [4]. Acquired causes of nonprogressive congenital ataxia include prenatally acquired cerebellar injury such as congenital cytomegalovirus infection, in utero cerebellar stroke, and perinatal disrupted development of the cerebellum as can be seen in premature infants and those with perinatal ischemic injury [51]. In the setting of chronic nonprogressive ataxia, imaging can be helpful in identifying the presence of congenital cerebellar, vermian, brainstem, and supratentorial brain malformations and acquired cerebellar disruptions due to prenatal or perinatal insult, although imaging can be normal in genetic etiologies [1,4,25,40]. CT Head Although CT may provide an assessment of major structural abnormalities in the posterior fossa, CT is less sensitive than MRI for assessment of intracranial structures [14,28]. The use of IV contrast is generally not warranted in assessment of brain structural abnormalities that present with chronic nonprogressive ataxia in children. Ataxia-Child CT Complete Spine There is no relevant literature to support the use of CT complete spine in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Head and Neck There is no relevant literature to support the use of CTA head and neck in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Head There is no relevant literature to support the use of CTA head in the initial evaluation of a child with chronic nonprogressive ataxia. CTA Neck There is no relevant literature to support the use of CTA neck in the initial evaluation of a child with chronic nonprogressive ataxia.