CT Neck Without and With IV Contrast There is no relevant literature to support the use of CT neck without and with IV contrast for the evaluation of known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, or cancer of unknown primary of the head and neck. CT Neck Without IV Contrast There is no relevant literature to support the use of CT neck without IV contrast for the evaluation of known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, or cancer of unknown primary of the head and neck. Contrast enhancement is imperative in order to correctly identify and delineate recurrence, distinguishing it from treatment changes. CTA Neck With IV Contrast There is no relevant literature to support the use of CTA of the neck with IV contrast in the follow-up imaging or evaluation of suspected or known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, Assessment of Head and Neck Cancer or cancer of unknown primary of the head and neck. In the specific case of recurrent disease encroaching on the carotid arteries, CTA of the neck can be used to identify patients at high risk of bleeding [41]. FDG-PET/CT Skull Base to Mid-Thigh FDG-PET/CT allows for the assessment of treatment response and detection and localization of recurrence, regional nodal disease, and distant metastases. The evaluation of the posttreatment of the neck is complicated by significant treatment-related changes that can be difficult to distinguish from persistent disease after therapy or recurrence. Studies have shown FDG-PET/CT to have high sensitivity and specificity for detection of local and nodal recurrence, with a higher sensitivity and similar or higher specificity to CT or MRI of the neck [117,119,126-128]. FDG-PET/CT has a very high NPV and therefore is very accurate in excluding recurrence [129-131].
Staging and Post Therapy Assessment of Head and Neck Cancer. CT Neck Without and With IV Contrast There is no relevant literature to support the use of CT neck without and with IV contrast for the evaluation of known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, or cancer of unknown primary of the head and neck. CT Neck Without IV Contrast There is no relevant literature to support the use of CT neck without IV contrast for the evaluation of known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, or cancer of unknown primary of the head and neck. Contrast enhancement is imperative in order to correctly identify and delineate recurrence, distinguishing it from treatment changes. CTA Neck With IV Contrast There is no relevant literature to support the use of CTA of the neck with IV contrast in the follow-up imaging or evaluation of suspected or known recurrence of treated cancer of the oral cavity, oropharynx, hypopharynx, larynx, Assessment of Head and Neck Cancer or cancer of unknown primary of the head and neck. In the specific case of recurrent disease encroaching on the carotid arteries, CTA of the neck can be used to identify patients at high risk of bleeding [41]. FDG-PET/CT Skull Base to Mid-Thigh FDG-PET/CT allows for the assessment of treatment response and detection and localization of recurrence, regional nodal disease, and distant metastases. The evaluation of the posttreatment of the neck is complicated by significant treatment-related changes that can be difficult to distinguish from persistent disease after therapy or recurrence. Studies have shown FDG-PET/CT to have high sensitivity and specificity for detection of local and nodal recurrence, with a higher sensitivity and similar or higher specificity to CT or MRI of the neck [117,119,126-128]. FDG-PET/CT has a very high NPV and therefore is very accurate in excluding recurrence [129-131].