CT Neck Neck CT in the evaluation of recurrent or persistent PHPT after prior surgery is most commonly performed without and with IV contrast (4-D parathyroid CT) [34], which is reflected in the published data regarding the performance of neck CT for parathyroid localization in the setting of prior failed surgery. There is no literature regarding the use of CT neck with IV contrast specifically limited to patients with recurrent or persistent PHPT. Additionally, there is no relevant literature regarding the use of CT neck without IV contrast in the evaluation of PHPT. In the setting of recurrent or persistent PHPT, retrospective studies report the sensitivity of CT neck without and with IV contrast to range between 50% and 91% and the PPV to range between 69% and 100% [29,36,40,97]. There is no relevant literature regarding the use of MRI without IV contrast in the evaluation of recurrent or persistent PHPT. Sestamibi Dual-Phase Scan Neck There is no relevant literature regarding the use of planar sestamibi dual-phase scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Dual-Phase Scan with SPECT or SPECT/CT Neck There are limited data regarding the use of sestamibi dual-phase scans with SPECT or SPECT/CT in the setting of prior surgery: Sestamibi Scan and I-123 Thyroid Scan There is no relevant literature regarding the use of planar sestamibi and I-123 scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Scan and Pertechnetate Thyroid Scan There is no relevant literature regarding the use of planar sestamibi and pertechnetate scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Scan and Pertechnetate Thyroid Scan with SPECT or SPECT/CT Neck There is no relevant literature regarding the use of sestamibi and pertechnetate scans with SPECT or SPECT/CT in the evaluation of recurrent or persistent PHPT after prior surgery.
Parathyroid Adenoma. CT Neck Neck CT in the evaluation of recurrent or persistent PHPT after prior surgery is most commonly performed without and with IV contrast (4-D parathyroid CT) [34], which is reflected in the published data regarding the performance of neck CT for parathyroid localization in the setting of prior failed surgery. There is no literature regarding the use of CT neck with IV contrast specifically limited to patients with recurrent or persistent PHPT. Additionally, there is no relevant literature regarding the use of CT neck without IV contrast in the evaluation of PHPT. In the setting of recurrent or persistent PHPT, retrospective studies report the sensitivity of CT neck without and with IV contrast to range between 50% and 91% and the PPV to range between 69% and 100% [29,36,40,97]. There is no relevant literature regarding the use of MRI without IV contrast in the evaluation of recurrent or persistent PHPT. Sestamibi Dual-Phase Scan Neck There is no relevant literature regarding the use of planar sestamibi dual-phase scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Dual-Phase Scan with SPECT or SPECT/CT Neck There are limited data regarding the use of sestamibi dual-phase scans with SPECT or SPECT/CT in the setting of prior surgery: Sestamibi Scan and I-123 Thyroid Scan There is no relevant literature regarding the use of planar sestamibi and I-123 scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Scan and Pertechnetate Thyroid Scan There is no relevant literature regarding the use of planar sestamibi and pertechnetate scans in the evaluation of recurrent or persistent PHPT after prior surgery. Sestamibi Scan and Pertechnetate Thyroid Scan with SPECT or SPECT/CT Neck There is no relevant literature regarding the use of sestamibi and pertechnetate scans with SPECT or SPECT/CT in the evaluation of recurrent or persistent PHPT after prior surgery.