SPECT or SPECT/CT MPI Rest and Stress Utilizing intravenously administered tracers, Single-photon emission computed tomography (SPECT) or SPECT/CT (ie, SPECT with CT attenuation correction) can provide insights into cardiac pathophysiology, including abnormalities of ventricular function (global and regional) and myocardial perfusion imaging (MPI) [23-25]. FDG-PET/CT Heart and Rb-82 PET/CT Heart Utilizing rubidium-82 (Rb-82), PET/CT is capable of reflecting myocardial physiology, including perfusion, wall motion, and cardiac flow reserve; this can be valuable in assessing HF [23-25]. Evaluation of myocardial viability can be performed utilizing fluorine-18-2-fluoro-2-deoxy-D-glucose (FDG) as the PET agent [23-25]. MRI Heart Cardiac MRI remains heavily reliant on electrocardiographic referencing of imaging data acquisition to the cardiac cycle and uses a magnetic field and radio waves to create detailed tomographic or volumetric images of high contrast. Depending upon the imaging acquisition employed and whether or not a gadolinium-based contrast agent was used and how and when administered relative to data acquisition, images demonstrating a range of abnormalities of (1) anatomy (eg, reduced thickness of ventricular wall, enlargement of atrial cavity, or increased thickness of pericardial sac); (2) histology (eg, myocardial edema, infiltration, deposition, or fibrosis); or (3) physiology (eg, depressed LVEF, restrictive transatrioventricular diastolic inflow, or reduced resting versus stress-induced myocardial strain or first-pass perfusion) [26-28]. These capabilities are potentially beneficial in assessing HF. Potential complications must be considered on a patient-by-patient basis before its use.
Suspected New Onset and Known Nonacute Heart Failure. SPECT or SPECT/CT MPI Rest and Stress Utilizing intravenously administered tracers, Single-photon emission computed tomography (SPECT) or SPECT/CT (ie, SPECT with CT attenuation correction) can provide insights into cardiac pathophysiology, including abnormalities of ventricular function (global and regional) and myocardial perfusion imaging (MPI) [23-25]. FDG-PET/CT Heart and Rb-82 PET/CT Heart Utilizing rubidium-82 (Rb-82), PET/CT is capable of reflecting myocardial physiology, including perfusion, wall motion, and cardiac flow reserve; this can be valuable in assessing HF [23-25]. Evaluation of myocardial viability can be performed utilizing fluorine-18-2-fluoro-2-deoxy-D-glucose (FDG) as the PET agent [23-25]. MRI Heart Cardiac MRI remains heavily reliant on electrocardiographic referencing of imaging data acquisition to the cardiac cycle and uses a magnetic field and radio waves to create detailed tomographic or volumetric images of high contrast. Depending upon the imaging acquisition employed and whether or not a gadolinium-based contrast agent was used and how and when administered relative to data acquisition, images demonstrating a range of abnormalities of (1) anatomy (eg, reduced thickness of ventricular wall, enlargement of atrial cavity, or increased thickness of pericardial sac); (2) histology (eg, myocardial edema, infiltration, deposition, or fibrosis); or (3) physiology (eg, depressed LVEF, restrictive transatrioventricular diastolic inflow, or reduced resting versus stress-induced myocardial strain or first-pass perfusion) [26-28]. These capabilities are potentially beneficial in assessing HF. Potential complications must be considered on a patient-by-patient basis before its use.