In this study, MRI performed better than CT, which had a pooled sensitivity and specificity of 51% (95% CI, 36%- 67%) and 87% (95% CI, 81%-92%), respectively [12]. Another meta-analysis of 72 studies showed MRI had comparable performance to CT and inferior performance to PET, with a sensitivity of 58% and a specificity of 93% compared to 75% and 98% for PET and 58% and 92% for CT [36]. MRI Abdomen Without IV Contrast MRI abdomen without IV contrast may be employed for the assessment of nodal and distant metastatic disease and may be obtained along with the pelvic MRI performed for local disease extent assessment. Although IV contrast administration is preferred because it may increase the conspicuity of small lesions, it still demonstrates inherent superior soft tissue contrast compared to CT, and the DWI/ADC images may help to detect small metastatic foci. MRI Pelvis Without and With IV Contrast Evaluation for pelvic and lower para-aortic lymph node metastases can be performed at the time of local disease assessment, preferably with IV contrast. Nodes are considered abnormal on MRI if their axial short axis is >0.8 cm in the pelvis or if they display abnormal morphologic characteristics such as rounded shape, loss of the normal fatty hilum, heterogenous signal, or more pronounced diffusion restriction than uninvolved lymph nodes. Using these criteria, a meta-analysis of 115 studies published from 2000 to 2019 showed MRI performed comparably with PET with a pooled sensitivity and specificity of 57% (95% CI, 49%-64%) and 93% (95% CI, 89%-95%), compared to 57% (95% CI, 48%-65%) and 95% (95% CI, 93%-97%) for PET. In this study, MRI performed better than CT, which had a pooled sensitivity and specificity of 51% 57% (95% CI, 49%-64%) and 93% (95% CI, 89%-95%), compared to 57% (95% CI, 48%-65%) and 95% (95% CI, 93%-97%), respectively [12].
Pretreatment Evaluation and Follow up of Invasive Cancer of the Cervix. In this study, MRI performed better than CT, which had a pooled sensitivity and specificity of 51% (95% CI, 36%- 67%) and 87% (95% CI, 81%-92%), respectively [12]. Another meta-analysis of 72 studies showed MRI had comparable performance to CT and inferior performance to PET, with a sensitivity of 58% and a specificity of 93% compared to 75% and 98% for PET and 58% and 92% for CT [36]. MRI Abdomen Without IV Contrast MRI abdomen without IV contrast may be employed for the assessment of nodal and distant metastatic disease and may be obtained along with the pelvic MRI performed for local disease extent assessment. Although IV contrast administration is preferred because it may increase the conspicuity of small lesions, it still demonstrates inherent superior soft tissue contrast compared to CT, and the DWI/ADC images may help to detect small metastatic foci. MRI Pelvis Without and With IV Contrast Evaluation for pelvic and lower para-aortic lymph node metastases can be performed at the time of local disease assessment, preferably with IV contrast. Nodes are considered abnormal on MRI if their axial short axis is >0.8 cm in the pelvis or if they display abnormal morphologic characteristics such as rounded shape, loss of the normal fatty hilum, heterogenous signal, or more pronounced diffusion restriction than uninvolved lymph nodes. Using these criteria, a meta-analysis of 115 studies published from 2000 to 2019 showed MRI performed comparably with PET with a pooled sensitivity and specificity of 57% (95% CI, 49%-64%) and 93% (95% CI, 89%-95%), compared to 57% (95% CI, 48%-65%) and 95% (95% CI, 93%-97%) for PET. In this study, MRI performed better than CT, which had a pooled sensitivity and specificity of 51% 57% (95% CI, 49%-64%) and 93% (95% CI, 89%-95%), compared to 57% (95% CI, 48%-65%) and 95% (95% CI, 93%-97%), respectively [12].