The sensitivity and specificity of MRI for the detection of pituitary abnormality in the patients with ONH and endocrinopathy are 68% to 96% and 83% to 92%, respectively [32,33]. MRI may also complement fundoscopic examination in the primary diagnosis of ONH by direct measurement of the optic nerve size [34]. There is no relevant literature to support the role for IV contrast in the initial evaluation of children without leukocoria with decreased visual acuity or vision loss due to congenital or developmental abnormality. MRI Head There is no relevant literature to support the use of MRI head alone in the initial evaluation of children without leukocoria with decreased visual acuity or vision loss due to congenital or developmental abnormality. MRI of the head is, however, often obtained in conjunction with MRI orbits. MRI Orbits MRI of the orbits alone is useful to evaluate for the abnormalities of the globe and orbits, but this is best performed in association with MRI of the brain, to assess the associated developmental abnormalities of the intracranial structures [2,32-34]. CT Head and Orbits There is no relevant literature to support the use of CT head and orbits in the initial evaluation of children with suspected OPG. CT Head There is no relevant literature to support the use of CT head in the initial evaluation of children with suspected OPG. Orbital Imaging and Vision Loss-Child CT Orbits There is no relevant literature to support the use of CT head in the initial evaluation of children with suspected OPG. CTA Head There is no relevant literature to support the use of CTA head in the initial evaluation of children with suspected OPG. MRA Head There is no relevant literature to support the use of MRA head in the initial evaluation of children with suspected OPG.
Orbital Imaging and Vision Loss Child. The sensitivity and specificity of MRI for the detection of pituitary abnormality in the patients with ONH and endocrinopathy are 68% to 96% and 83% to 92%, respectively [32,33]. MRI may also complement fundoscopic examination in the primary diagnosis of ONH by direct measurement of the optic nerve size [34]. There is no relevant literature to support the role for IV contrast in the initial evaluation of children without leukocoria with decreased visual acuity or vision loss due to congenital or developmental abnormality. MRI Head There is no relevant literature to support the use of MRI head alone in the initial evaluation of children without leukocoria with decreased visual acuity or vision loss due to congenital or developmental abnormality. MRI of the head is, however, often obtained in conjunction with MRI orbits. MRI Orbits MRI of the orbits alone is useful to evaluate for the abnormalities of the globe and orbits, but this is best performed in association with MRI of the brain, to assess the associated developmental abnormalities of the intracranial structures [2,32-34]. CT Head and Orbits There is no relevant literature to support the use of CT head and orbits in the initial evaluation of children with suspected OPG. CT Head There is no relevant literature to support the use of CT head in the initial evaluation of children with suspected OPG. Orbital Imaging and Vision Loss-Child CT Orbits There is no relevant literature to support the use of CT head in the initial evaluation of children with suspected OPG. CTA Head There is no relevant literature to support the use of CTA head in the initial evaluation of children with suspected OPG. MRA Head There is no relevant literature to support the use of MRA head in the initial evaluation of children with suspected OPG.