Chest CT with or without intravenous (IV) contrast may be obtained as a part of posttherapy surveillance in selected high-risk groups or patients with an advanced FIGO stage [81,83,84]. MRI Pelvis Recurrent tumor appears as a mass with high signal intensity on T2WI and intensely enhances following IV contrast administration [93]. MRI has a role in the evaluation of surgical resectability if the pelvis is the sole site of recurrence [36]. However, there is insufficient data to support the routine use of MRI for surveillance of asymptomatic patients [80]. MRI Abdomen MRI may also be used for assessment of metastasis of the liver, adrenals, brain, bones, and soft-tissue when metastases are clinically suspected and need further investigation. However, there is insufficient data to support the routine use of MRI for surveillance of asymptomatic patients [80]. Radiography Chest Chest radiographs have been advocated for the detection of asymptomatic chest recurrences, often on a semi-annual or annual basis. However, the rate of detection for asymptomatic chest recurrences found on chest radiographs ranges only from 0% to 20% [87,90]. Thus, this procedure may be useful when lung metastases are clinically suspected. US Pelvis Transvaginal Because many of the recurrences are detected during physical examination, the use of routine pelvic is not advocated [21,87]. US Pelvis Transabdominal Because many of the recurrences are detected during the physical examination, the use of routine pelvic US is not advocated [21,87]. US Abdomen Because many of the recurrences are detected during the physical examination, the use of abdominal US is not advocated [21,87]. Variant 6: Posttherapy evaluation of clinically suspected recurrence of known endometrial cancer. Most patients are cured following primary treatment, and approximately 25% to 30% of patients with high-risk EC may develop recurrent disease [91].
Pretreatment Evaluation and Follow Up of Endometrial Cancer. Chest CT with or without intravenous (IV) contrast may be obtained as a part of posttherapy surveillance in selected high-risk groups or patients with an advanced FIGO stage [81,83,84]. MRI Pelvis Recurrent tumor appears as a mass with high signal intensity on T2WI and intensely enhances following IV contrast administration [93]. MRI has a role in the evaluation of surgical resectability if the pelvis is the sole site of recurrence [36]. However, there is insufficient data to support the routine use of MRI for surveillance of asymptomatic patients [80]. MRI Abdomen MRI may also be used for assessment of metastasis of the liver, adrenals, brain, bones, and soft-tissue when metastases are clinically suspected and need further investigation. However, there is insufficient data to support the routine use of MRI for surveillance of asymptomatic patients [80]. Radiography Chest Chest radiographs have been advocated for the detection of asymptomatic chest recurrences, often on a semi-annual or annual basis. However, the rate of detection for asymptomatic chest recurrences found on chest radiographs ranges only from 0% to 20% [87,90]. Thus, this procedure may be useful when lung metastases are clinically suspected. US Pelvis Transvaginal Because many of the recurrences are detected during physical examination, the use of routine pelvic is not advocated [21,87]. US Pelvis Transabdominal Because many of the recurrences are detected during the physical examination, the use of routine pelvic US is not advocated [21,87]. US Abdomen Because many of the recurrences are detected during the physical examination, the use of abdominal US is not advocated [21,87]. Variant 6: Posttherapy evaluation of clinically suspected recurrence of known endometrial cancer. Most patients are cured following primary treatment, and approximately 25% to 30% of patients with high-risk EC may develop recurrent disease [91].