Although surgical options exist for locally advanced disease, they often involve a degree of pelvic exenteration and therefore confer substantial morbidity. For this reason, the management paradigm for locally advanced disease has largely trended toward definitive radiation therapy with concurrent chemotherapy [1,5]. Though data on the use of imaging in vaginal cancer are sparse, insights derived from the study of imaging in cervical cancer have reasonable generalizability to vaginal cancer because of similar tumor biology. Moreover, given the trend toward definitive chemoradiation for both cancers in all but early stage lesions, principles of postchemoradiation the recommendations outlined in this document are informed by principles translated from the literature on cervical cancer. The American College of Radiology seeks and encourages collaboration with other organizations on the development of the ACR Appropriateness Criteria through representation of such organizations on expert panels. Participation on the expert panel does not necessarily imply endorsement of the final document by individual contributors or their respective organization. Reprint requests to: publications@acr.org Staging and Follow-up of Primary Vaginal Cancer imaging in initial and adaptive radiation planning for vaginal cancer is not specifically addressed in this document, and analogous principles for cervical cancer are covered in extensive detail elsewhere [6]. OR Discussion of Procedures by Variant Variant 1: Vaginal cancer. Pretreatment staging. Initial imaging. Although the 2009 FIGO staging system for vaginal cancer indicates that findings on advanced imaging (CT, MRI, PET/CT) should not modify stage designation [4], such imaging findings are routinely employed in clinical practice to prognosticate and guide management decisions in patients with vaginal cancer.
Staging and Follow up of Primary Vaginal Cancer. Although surgical options exist for locally advanced disease, they often involve a degree of pelvic exenteration and therefore confer substantial morbidity. For this reason, the management paradigm for locally advanced disease has largely trended toward definitive radiation therapy with concurrent chemotherapy [1,5]. Though data on the use of imaging in vaginal cancer are sparse, insights derived from the study of imaging in cervical cancer have reasonable generalizability to vaginal cancer because of similar tumor biology. Moreover, given the trend toward definitive chemoradiation for both cancers in all but early stage lesions, principles of postchemoradiation the recommendations outlined in this document are informed by principles translated from the literature on cervical cancer. The American College of Radiology seeks and encourages collaboration with other organizations on the development of the ACR Appropriateness Criteria through representation of such organizations on expert panels. Participation on the expert panel does not necessarily imply endorsement of the final document by individual contributors or their respective organization. Reprint requests to: publications@acr.org Staging and Follow-up of Primary Vaginal Cancer imaging in initial and adaptive radiation planning for vaginal cancer is not specifically addressed in this document, and analogous principles for cervical cancer are covered in extensive detail elsewhere [6]. OR Discussion of Procedures by Variant Variant 1: Vaginal cancer. Pretreatment staging. Initial imaging. Although the 2009 FIGO staging system for vaginal cancer indicates that findings on advanced imaging (CT, MRI, PET/CT) should not modify stage designation [4], such imaging findings are routinely employed in clinical practice to prognosticate and guide management decisions in patients with vaginal cancer.