Extrapolation of data from MRI heart function and morphology without and with IV contrast for patients with known CAD is provided below with a note that there is no information available regarding the presence or absence of chest pain in patients included in those studies [46,48,49,51,52]. A single-center prospective study of 884 patients with known (70%) or suspected (30%) CAD demonstrated that inducible LV wall motion abnormalities during dobutamine CMR predicts cardiac death and myocardial ischemia [46]. A single-center prospective study focusing on women with known or suspected CAD and variable clinical symptoms demonstrated that, similar to men, dobutamine CMR can identify cardiac risk in women with known or suspected IHD [47]. A single-center study of 815 consecutive patients referred for evaluation of suspected myocardial ischemia over a 10-year period has shown that stress CMR with protocol, including stress and rest myocardial perfusion, ventricular function, and late gadolinium enhancement, effectively reclassifies patient risk beyond standard clinical variables, specifically in patients at a moderate to high pretest clinical risk and in patients with established CAD [48]. Chronic Chest Pain-High Probability of CAD Stress CMR has a high NPV for adverse cardiac events in patients with known or suspected CAD [46,47]. A meta- analysis of 14 studies has shown that MRI heart function stress has a high NPV for adverse cardiac events, and the absence of inducible perfusion defect or wall motion abnormality shows a similar ability to identify patients with a low risk for adverse cardiac events among patients with known or suspected CAD [49].
Chronic Chest Pain High Probability of Coronary Artery Disease PCAs. Extrapolation of data from MRI heart function and morphology without and with IV contrast for patients with known CAD is provided below with a note that there is no information available regarding the presence or absence of chest pain in patients included in those studies [46,48,49,51,52]. A single-center prospective study of 884 patients with known (70%) or suspected (30%) CAD demonstrated that inducible LV wall motion abnormalities during dobutamine CMR predicts cardiac death and myocardial ischemia [46]. A single-center prospective study focusing on women with known or suspected CAD and variable clinical symptoms demonstrated that, similar to men, dobutamine CMR can identify cardiac risk in women with known or suspected IHD [47]. A single-center study of 815 consecutive patients referred for evaluation of suspected myocardial ischemia over a 10-year period has shown that stress CMR with protocol, including stress and rest myocardial perfusion, ventricular function, and late gadolinium enhancement, effectively reclassifies patient risk beyond standard clinical variables, specifically in patients at a moderate to high pretest clinical risk and in patients with established CAD [48]. Chronic Chest Pain-High Probability of CAD Stress CMR has a high NPV for adverse cardiac events in patients with known or suspected CAD [46,47]. A meta- analysis of 14 studies has shown that MRI heart function stress has a high NPV for adverse cardiac events, and the absence of inducible perfusion defect or wall motion abnormality shows a similar ability to identify patients with a low risk for adverse cardiac events among patients with known or suspected CAD [49].