Characterization of bone tumors as benign or malignant with MR spectroscopy has shown promise in two small observational studies, although further research is needed [48,49]. Primary Bone Tumors Radiography Skeletal Survey Radiographic survey of the whole body is of limited utility in the evaluation of a suspected primary bone tumor with an indeterminate or aggressive appearance detected on radiographs. The primary utility of radiographic skeletal survey is in evaluating the appearance and distribution of polyostotic bone lesions, which are most commonly multiple myeloma or metastases rather than primary bone lesions. Bone Scan Whole Body Despite its historical utility in further characterizing lesions detected on radiographs, there are no controlled studies in the literature over the last 10 years specifically evaluating the efficacy of bone scan in this role. Bone Scan Whole Body with SPECT or SPECT/CT Area of Interest Despite its historical utility in further characterizing lesions detected on radiographs, there are no controlled studies in the literature over the last 10 years specifically evaluating the efficacy of bone scan in this role. However, recent advances in technology, such as SPECT/CT, may provide a useful tool in the evaluation of primary bone tumors. A retrospective review of 99 patients with 108 vertebral lesions showed that SPECT/CT was superior to planar scintigraphy and SPECT alone, but not CT alone, in the characterization of indeterminate vertebral lesions found on bone scintigraphy [50]. US Area of Interest US is not routinely used in the evaluation of indeterminate or aggressive bone lesions seen on radiographs. There is no relevant literature regarding the use of US in the evaluation of an indeterminate or aggressive lesion detected on radiographs. CT Area of Interest There is no relevant literature regarding the use of CT in the evaluation of bone lesions incidentally found on MRI.
Primary Bone Tumors. Characterization of bone tumors as benign or malignant with MR spectroscopy has shown promise in two small observational studies, although further research is needed [48,49]. Primary Bone Tumors Radiography Skeletal Survey Radiographic survey of the whole body is of limited utility in the evaluation of a suspected primary bone tumor with an indeterminate or aggressive appearance detected on radiographs. The primary utility of radiographic skeletal survey is in evaluating the appearance and distribution of polyostotic bone lesions, which are most commonly multiple myeloma or metastases rather than primary bone lesions. Bone Scan Whole Body Despite its historical utility in further characterizing lesions detected on radiographs, there are no controlled studies in the literature over the last 10 years specifically evaluating the efficacy of bone scan in this role. Bone Scan Whole Body with SPECT or SPECT/CT Area of Interest Despite its historical utility in further characterizing lesions detected on radiographs, there are no controlled studies in the literature over the last 10 years specifically evaluating the efficacy of bone scan in this role. However, recent advances in technology, such as SPECT/CT, may provide a useful tool in the evaluation of primary bone tumors. A retrospective review of 99 patients with 108 vertebral lesions showed that SPECT/CT was superior to planar scintigraphy and SPECT alone, but not CT alone, in the characterization of indeterminate vertebral lesions found on bone scintigraphy [50]. US Area of Interest US is not routinely used in the evaluation of indeterminate or aggressive bone lesions seen on radiographs. There is no relevant literature regarding the use of US in the evaluation of an indeterminate or aggressive lesion detected on radiographs. CT Area of Interest There is no relevant literature regarding the use of CT in the evaluation of bone lesions incidentally found on MRI.