Rather, as SHPT is typically a disorder of MGD and is therefore treated with BNE, the role of initial imaging is to accurately identify all eutopic and potential ectopic or supernumerary glands in an attempt to decrease surgical failure rates [12-14]; accordingly, these criteria focus on imaging test sensitivity and PPV. It is possible that multiple imaging modalities may be utilized in combination during the initial imaging evaluation of SHPT in an attempt to maximize the accuracy and confidence of parathyroid localization via concordant imaging results. This is supported by limited literature specific to SHPT [12] and otherwise inferred from data regarding PHPT [16-23] showing improved sensitivity and PPV in parathyroid lesion localization with a combination of examinations over each examination in isolation. MRI Neck There is no relevant literature regarding the use of MRI neck performed without IV contrast, with IV contrast, or without and with IV contrast in the evaluation of SHPT. Parathyroid Adenoma neoplasia; patients with SHPT comprised 55% of the cohort. On a per-lesion basis, the reported sensitivity of sestamibi dual-phase scans with SPECT in detecting ectopic glands was 29% [110]. Sestamibi Scan and I-123 Thyroid Scan There is no relevant literature regarding the use of planar sestamibi scan and I-123 thyroid scan in the evaluation of SHPT. Sestamibi Scan and Pertechnetate Thyroid Scan There is no relevant literature regarding the use of planar sestamibi scan and pertechnetate thyroid scan in the evaluation of SHPT. Sestamibi Scan and Pertechnetate Thyroid Scan with SPECT or SPECT/CT Neck There is no relevant literature regarding the use of sestamibi scan and pertechnetate thyroid scan with SPECT or SPECT/CT in the evaluation of SHPT. Venous Sampling Parathyroid There is no relevant literature regarding the use of venous sampling in the evaluation of SHPT. Variant 4: Adult or child. Tertiary hyperparathyroidism. Initial imaging.
Parathyroid Adenoma. Rather, as SHPT is typically a disorder of MGD and is therefore treated with BNE, the role of initial imaging is to accurately identify all eutopic and potential ectopic or supernumerary glands in an attempt to decrease surgical failure rates [12-14]; accordingly, these criteria focus on imaging test sensitivity and PPV. It is possible that multiple imaging modalities may be utilized in combination during the initial imaging evaluation of SHPT in an attempt to maximize the accuracy and confidence of parathyroid localization via concordant imaging results. This is supported by limited literature specific to SHPT [12] and otherwise inferred from data regarding PHPT [16-23] showing improved sensitivity and PPV in parathyroid lesion localization with a combination of examinations over each examination in isolation. MRI Neck There is no relevant literature regarding the use of MRI neck performed without IV contrast, with IV contrast, or without and with IV contrast in the evaluation of SHPT. Parathyroid Adenoma neoplasia; patients with SHPT comprised 55% of the cohort. On a per-lesion basis, the reported sensitivity of sestamibi dual-phase scans with SPECT in detecting ectopic glands was 29% [110]. Sestamibi Scan and I-123 Thyroid Scan There is no relevant literature regarding the use of planar sestamibi scan and I-123 thyroid scan in the evaluation of SHPT. Sestamibi Scan and Pertechnetate Thyroid Scan There is no relevant literature regarding the use of planar sestamibi scan and pertechnetate thyroid scan in the evaluation of SHPT. Sestamibi Scan and Pertechnetate Thyroid Scan with SPECT or SPECT/CT Neck There is no relevant literature regarding the use of sestamibi scan and pertechnetate thyroid scan with SPECT or SPECT/CT in the evaluation of SHPT. Venous Sampling Parathyroid There is no relevant literature regarding the use of venous sampling in the evaluation of SHPT. Variant 4: Adult or child. Tertiary hyperparathyroidism. Initial imaging.