Compute $\int_{-\infty}^{+\infty}(1+\frac{1}{v^2})\exp(-\frac{u^2}{2\sigma_1^2\sigma_2^2}(\sigma_2v+\frac{\sigma_1}{v})^2)\,dv$ 
Compute $$\int_{-\infty}^{+\infty}(1+\frac{1}{v^2})e^{-\frac{u^2}{2\sigma_1^2\sigma_2^2}(\sigma_2v+\frac{\sigma_1}{v})^2}\,dv$$

Does this integral has a close form solution? What if $\sigma_1=\sigma_2=1$, $u=\sqrt2$, i.e, $$\int_{-\infty}^{+\infty}(1+\frac{1}{v^2})e^{-(v+\frac{1}{v})^2}dv$$

First we analyze the special case in which $u=\sqrt2$, and $\sigma_1=\sigma_2=1$.  Noting that $\left(x+\frac 1x\right)^2=\left(x-\frac 1x\right)^2 +4$, we have
$$\begin{align}
I&=\int_{-\infty}^\infty\left(1+\frac1{x^2}\right)e^{-\left(x+\frac 1x\right)^2}\,dx\\\\
&=e^{-4}\int_{-\infty}^\infty\left(1+\frac1{x^2}\right)e^{-\left(x-\frac 1x\right)^2}\,dx \tag 1\\\\
&=2e^{-4}\int_{-\infty}^\infty e^{-u^2}\,du \tag 2\\\\
&=2\sqrt{\pi}e^{-4}
\end{align}$$

CAUTION: 
In going from $(1)$ to $(2)$, we first split the integral as 
$$\int_{-\infty}^\infty\left(1+\frac1{x^2}\right)e^{-\left(x-\frac 1x\right)^2}\,dx=\int_{-\infty}^0 \left(1+\frac1{x^2}\right)e^{-\left(x-\frac 1x\right)^2}\,dx+\int_{0}^\infty\left(1+\frac1{x^2}\right)e^{-\left(x-\frac 1x\right)^2}\,dx \tag 3$$
Then, we separately enforce the substitution $u=x-\frac1x$ in each of the integrals on the right-hand side of $(3)$.


For the general case, we enforce the substitution $x\to \sqrt{\frac{\sigma_1}{\sigma_2}}x$ to obtain
$$\begin{align}
I&=\sqrt{\frac{\sigma_2}{\sigma_1}}\int_{-\infty}^\infty \left(\frac{\sigma_1}{\sigma_2}+\frac1{x^2}\right)e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x+\frac 1x\right)^2}\,dx\\\\
&=\sqrt{\frac{\sigma_2}{\sigma_1}}\int_{-\infty}^\infty \left(1+\frac1{x^2}\right)e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x+\frac 1x\right)^2}\,dx+\sqrt{\frac{\sigma_2}{\sigma_1}}\left(\frac{\sigma_1}{\sigma_2}-1\right)\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x+\frac 1x\right)^2}\,dx\\\\
&=2\sqrt{\frac{\sigma_2}{\sigma_1}}e^{-2\frac{u^2}{\sigma_1\sigma_1}}\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,d\left(x-\frac1x\right)\\\\
&+\sqrt{\frac{\sigma_2}{\sigma_1}}\left(\frac{\sigma_1}{\sigma_2}-1\right)e^{-2\frac{u^2}{\sigma_1\sigma_1}}\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,dx\\\\
&=2\sigma_2e^{-2\frac{u^2}{\sigma_1\sigma_1}}\sqrt{\frac{2\pi}{u^2}}+\sqrt{\frac{\sigma_2}{\sigma_1}}\left(\frac{\sigma_1}{\sigma_2}-1\right)e^{-\frac{u^2}{2\sigma_1\sigma_1}}\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,dx \tag4
\end{align}$$
Making the substitution $x\to 1/x$ in the integral on the right-hand side of $(4)$ over the intervals $0$ to $\infty$ and $-\infty$ to $0$ separately, reveals
$$\begin{align}
\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,dx&=\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\frac{1}{x^2}\,dx\\\\
&= \frac12\int_{-\infty}^\infty \left(1+\frac1{x^2}\right)e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,dx\\\\
&=\int_{-\infty}^\infty e^{-\frac{u^2}{2\sigma_1\sigma_1}\left(x-\frac 1x\right)^2}\,d\left(x-\frac1x\right)\\\\
&=\sqrt{\frac{2\pi \sigma_1\sigma_2}{u^2}}\tag 5
\end{align}$$
Substituting $(5)$ into $(4)$ yields

$$\bbox[5px,border:2px solid #C0A000]{I=\left(\sigma_1+\sigma_2\right)\sqrt{\frac{2\pi}{u^2}}e^{-2\frac{u^2}{\sigma_1\sigma_1}}}$$

