xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT06040879</url>
    </required_header>
    <id_info>
      <org_study_id>HMU09.2023</org_study_id>
      <nct_id>NCT06040879</nct_id>
    </id_info>
    <brief_title>PENG Block and Lateral Femoral Cutaneous Nerve Block For Hip Replacement Surgery</brief_title>
    <official_title>Postoperative Analgesia Outcomes Of Pericapsular Nerve Group Block (PENG Block) Combined With Lateral Femoral Cutaneous Nerve Block After Hip Replacement Surgery: A Randomized Controlled Study</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>Hanoi Medical University</agency>
        <agency_class>Other</agency_class>
      </lead_sponsor>
    </sponsors>
    <source>Hanoi Medical University</source>
    <oversight_info>
      <has_dmc>Yes</has_dmc>
      <is_fda_regulated_drug>No</is_fda_regulated_drug>
      <is_fda_regulated_device>No</is_fda_regulated_device>
    </oversight_info>
    <brief_summary>
      <textblock>
        Background: this study aimed to describe the pain relief outcomes after hip replacement&#xD;
        surgery by continuous Pericapsular Nerve Group Block (PENG Block) in combination with lateral&#xD;
        femoral cutaneous nerve (LFCN) block under the guidance of ultrasound.&#xD;
  &#xD;
        Methods: patients who had hip surgery at E University hospital, Hanoi, Vietnam from August&#xD;
        2021 to August 2022 belonged to two groups: group of patients with pain relief with PENG&#xD;
        block in combination with LFCN block (PENG BLOCK group) and group of patients with&#xD;
        patient-controlled intravenous analgesia (PCA group). Outcomes regarding clinical and pain&#xD;
        score from initiation of insertion or PCA insertion (H0) to after 72 hours (H72) were&#xD;
        recorded.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        First, patients were explained about the study and asked to sign written informed consent if&#xD;
        they agreed to participate in the study. Next, the patient was instructed to use the visual&#xD;
        analogue scale (VAS) for pain score, as well as how to press the button to request pain&#xD;
        relief. Then, a monitor was installed and operated to assess the clinical parameters&#xD;
        (electrocardiogram, blood pressure, SpO2, arterial blood pressure, temperature). The patient&#xD;
        was oxygenated 3-5 liters/minute and performed a peripheral intravenous line, with an 18G&#xD;
        catheter, infused with 0.9% NaCl solution. Spinal anesthesia was administered with&#xD;
        ropivacaine 0.5% and fentanyl.&#xD;
  &#xD;
        During and after the surgery, a group of patients received intravenous morphine analgesia via&#xD;
        PCA (concentration 1mg/ml, bolus dose of 1mg, lock time 10 minutes, maximum dose 10mg/4&#xD;
        hours). The remaining group of patients receive pain relief by PENG block and LFCN block. In&#xD;
        this group, the ultrasound probe was placed horizontally from the anterior superior iliac&#xD;
        spine, and was moved along the femoral arc defining the pubic spine. Then, the transducer was&#xD;
        rotated 45 degrees, moved parallel to the femoral arch identifying the anterior inferior&#xD;
        iliac spine (AIIS), iliopubic eminence (IPE) and inferior lumbosacral head. The ultrasound&#xD;
        probe was moved lightly until the upper end of the femoral head was identified. Next, a 120&#xD;
        mm Tuohy 18G anesthetic needle was used under ultrasound guidance, which was moved lateral to&#xD;
        medial in the plane between the ultrasound transducer and the superior tip of the femoral&#xD;
        head. Then, 10 mL of ropivacaine 0.25% was injected through the anesthetic needle tip.&#xD;
  &#xD;
        Data were collected at different times including: before surgery, before anesthesia, during&#xD;
        surgery and after surgery. The information was recorded in the medical record.&#xD;
  &#xD;
        Preoperative data: the collected information included the general characteristics of the&#xD;
        study patients including age, gender, weight, height, history of smoking/motion sickness,&#xD;
        diagnosis, health classification according to ASA, liver and kidney function tests. With&#xD;
        pre-anesthesia data, information was collected including pulse, blood pressure, respiratory&#xD;
        rate, SpO2.&#xD;
  &#xD;
        Intraoperative data: the information collected includes information about anesthesia and&#xD;
        surgical procedure.&#xD;
  &#xD;
        Post-operative data: the collected information includes blood test results (urea, creatinine,&#xD;
        liver enzymes), pain score (Visual analogue scale - VAS - scale from 0 to 10, the higher the&#xD;
        score, the higher the pain level. more), analgesic drugs consumption status, respiratory and&#xD;
        circulatory changes, adverse events, and analgesic satisfaction. Time was recorded from&#xD;
        initiation of catheterization or PCA insertion (H0) to after 72 hours (H72).&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Completed</overall_status>
    <start_date type="Actual">August 1, 2021</start_date>
    <completion_date type="Actual">September 3, 2022</completion_date>
    <primary_completion_date type="Actual">August 31, 2022</primary_completion_date>
    <phase>N/A</phase>
    <study_type>Interventional</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <allocation>Randomized</allocation>
      <intervention_model>Parallel Assignment</intervention_model>
      <intervention_model_description>PCA group and PENG BLOCK group</intervention_model_description>
      <primary_purpose>Supportive Care</primary_purpose>
      <masking>Single (Participant)</masking>
    </study_design_info>
    <primary_outcome>
      <measure>VAS score at rest and on movement</measure>
      <time_frame>Time was recorded from initiation of catheterization or PCA insertion (H0) to after 72 hours (H72)</time_frame>
      <description>the average VAS score (Visual Analogue Scale) at rest and on movement of both groups. The Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be'). Ask the patient to rate their current level of pain by placing a mark on the line. Use a ruler to measure the distance in centimetres from the 'no pain marker' (or zero) to the current pain mark.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Side effects</measure>
      <time_frame>Time was recorded from initiation of catheterization or PCA insertion (H0) to after 72 hours (H72)</time_frame>
      <description>Rate of vomitting/nausea, itchy, urinary retention, respiratory failure postoperative of both groups.</description>
    </primary_outcome>
    <number_of_arms>2</number_of_arms>
    <enrollment type="Actual">60</enrollment>
    <condition>POSTOPERATIVE ANALGESIA</condition>
    <arm_group>
      <arm_group_label>PENG BLOCK</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>receiving pain relief through PENG and LFCN block</description>
    </arm_group>
    <arm_group>
      <arm_group_label>PCA</arm_group_label>
      <arm_group_type>Active Comparator</arm_group_type>
      <description>receiving morphine PCA analgesia</description>
    </arm_group>
    <intervention>
      <intervention_type>Procedure</intervention_type>
      <intervention_name>PERICAPSULAR NERVE GROUP BLOCK COMBINED WITH LATERAL FEMORAL CUTANEOUS NERVE BLOCK</intervention_name>
      <description>During and after the surgery, a group of patients received intravenous morphine analgesia via PCA (concentration 1mg/ml, bolus dose of 1mg, lock time 10 minutes, maximum dose 10mg/4 hours). The remaining group of patients receive pain relief by PENG block and LFCN block. In this group, the ultrasound probe was placed horizontally from the anterior superior iliac spine, and was moved along the femoral arc defining the pubic spine. Then, the transducer was rotated 45 degrees, moved parallel to the femoral arch identifying the anterior inferior iliac spine (AIIS), iliopubic eminence (IPE) and inferior lumbosacral head. The ultrasound probe was moved lightly until the upper end of the femoral head was identified. Next, a 120 mm Tuohy 18G anesthetic needle was used under ultrasound guidance, which was moved lateral to medial in the plane between the ultrasound transducer and the superior tip of the femoral head. Then, 10 mL of ropivacaine 0.25% was injected through the anesthetic needle tip</description>
      <arm_group_label>PCA</arm_group_label>
      <arm_group_label>PENG BLOCK</arm_group_label>
    </intervention>
    <eligibility>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
            -  American Society of Anesthesiologists (ASA) physical status I-III.&#xD;
  &#xD;
            -  Patients had hip replacement surgery.&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
            -  infection of the anesthetized area.&#xD;
  &#xD;
            -  coagulation disorders&#xD;
  &#xD;
            -  organs dysfunction&#xD;
  &#xD;
            -  allergy to anesthetics&#xD;
  &#xD;
            -  did not cooperate with physicians&#xD;
  &#xD;
            -  history of opioid dependence&#xD;
  &#xD;
            -  inability to participate in the study&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>18 Years</minimum_age>
      <maximum_age>80 Years</maximum_age>
      <healthy_volunteers>No</healthy_volunteers>
    </eligibility>
    <overall_official>
      <last_name>Tu Nguyen, Professor</last_name>
      <role>Study Director</role>
      <affiliation>Hanoi Medical University</affiliation>
    </overall_official>
    <location>
      <facility>
        <name>Hanoi Medical University</name>
        <address>
          <city>Hanoi</city>
          <country>Vietnam</country>
        </address>
      </facility>
    </location>
    <location_countries>
      <country>Vietnam</country>
    </location_countries>
    <link>
      <url>https://www.who.int/news-room/fact-sheets/detail/musculoskeletal-conditions</url>
      <description>Related Info</description>
    </link>
    <results_reference>
      <citation>Ferguson RJ, Palmer AJ, Taylor A, Porter ML, Malchau H, Glyn-Jones S. Hip replacement. Lancet. 2018 Nov 3;392(10158):1662-1671. doi: 10.1016/S0140-6736(18)31777-X.</citation>
      <PMID>30496081</PMID>
    </results_reference>
    <results_reference>
      <citation>Ferrata P, Carta S, Fortina M, Scipio D, Riva A, Di Giacinto S. Painful hip arthroplasty: definition. Clin Cases Miner Bone Metab. 2011 May;8(2):19-22.</citation>
      <PMID>22461810</PMID>
    </results_reference>
    <results_reference>
      <citation>YaDeau JT, Tedore T, Goytizolo EA, Kim DH, Green DS, Westrick A, Fan R, Rade MC, Ranawat AS, Coleman SH, Kelly BT. Lumbar plexus blockade reduces pain after hip arthroscopy: a prospective randomized controlled trial. Anesth Analg. 2012 Oct;115(4):968-72. doi: 10.1213/ANE.0b013e318265bacd. Epub 2012 Jul 19.</citation>
      <PMID>22822195</PMID>
    </results_reference>
    <results_reference>
      <citation>Duarte LT, Beraldo PS, Saraiva RA. [Effects of epidural analgesia and continuous lumbar plexus block on functional rehabilitation after total hip arthroplasty]. Rev Bras Anestesiol. 2009 Sep-Oct;59(5):531-44. doi: 10.1016/s0034-7094(09)70078-9. Portuguese.</citation>
      <PMID>19784509</PMID>
    </results_reference>
    <results_reference>
      <citation>Singelyn FJ, Ferrant T, Malisse MF, Joris D. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous femoral nerve sheath block on rehabilitation after unilateral total-hip arthroplasty. Reg Anesth Pain Med. 2005 Sep-Oct;30(5):452-7. doi: 10.1016/j.rapm.2005.05.008.</citation>
      <PMID>16135349</PMID>
    </results_reference>
    <results_reference>
      <citation>Lin DY, Morrison C, Brown B, Saies AA, Pawar R, Vermeulen M, Anderson SR, Lee TS, Doornberg J, Kroon HM, Jaarsma RL. Pericapsular nerve group (PENG) block provides improved short-term analgesia compared with the femoral nerve block in hip fracture surgery: a single-center double-blinded randomized comparative trial. Reg Anesth Pain Med. 2021 May;46(5):398-403. doi: 10.1136/rapm-2020-102315. Epub 2021 Feb 26.</citation>
      <PMID>33637625</PMID>
    </results_reference>
    <results_reference>
      <citation>Shafiq F, Hamid M, Samad K. Complications and interventions associated with epidural analgesia for postoperative pain relief in a tertiary care hospital. Middle East J Anaesthesiol. 2010 Oct;20(6):827-32.</citation>
      <PMID>21526668</PMID>
    </results_reference>
    <results_reference>
      <citation>Rasouli MR, Viscusi ER. Adductor Canal Block for Knee Surgeries: An Emerging Analgesic Technique. Arch Bone Jt Surg. 2017 May;5(3):131-132. No abstract available.</citation>
      <PMID>28656158</PMID>
    </results_reference>
    <results_reference>
      <citation>Kamel I, Ahmed MF, Sethi A. Regional anesthesia for orthopedic procedures: What orthopedic surgeons need to know. World J Orthop. 2022 Jan 18;13(1):11-35. doi: 10.5312/wjo.v13.i1.11. eCollection 2022 Jan 18.</citation>
      <PMID>35096534</PMID>
    </results_reference>
    <verification_date>September 2023</verification_date>
    <study_first_submitted>September 7, 2023</study_first_submitted>
    <study_first_submitted_qc>September 14, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">September 18, 2023</study_first_posted>
    <last_update_submitted>September 14, 2023</last_update_submitted>
    <last_update_submitted_qc>September 14, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">September 18, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Sponsor</responsible_party_type>
    </responsible_party>
    <keyword>Pericapsular Nerve Group Block</keyword>
    <keyword>lateral femoral cutaneous nerve</keyword>
    <keyword>multimodal analgesia</keyword>
    <keyword>ultrasound-guided analgesia</keyword>
    <keyword>patient-controlled analgesia</keyword>
    <condition_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Agnosia</mesh_term>
    </condition_browse>
    <patient_data>
      <sharing_ipd>Yes</sharing_ipd>
      <ipd_description>We agree that all results and conclusion of this research will be used fully for other researchers</ipd_description>
      <ipd_info_type>Study Protocol</ipd_info_type>
      <ipd_info_type>Statistical Analysis Plan (SAP)</ipd_info_type>
      <ipd_info_type>Informed Consent Form (ICF)</ipd_info_type>
      <ipd_info_type>Clinical Study Report (CSR)</ipd_info_type>
      <ipd_info_type>Analytic Code</ipd_info_type>
      <ipd_time_frame>from September 2023 to the unidentified time</ipd_time_frame>
      <ipd_access_criteria>anesthesiologists, surgeons all over the world</ipd_access_criteria>
    </patient_data>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT06040879
  org study id: HMU09.2023
  nct id: NCT06040879
  lead sponsor: 
  has dmc: Yes
  is fda regulated drug: No
  is fda regulated device: No
  Background: this study aimed to describe the pain relief outcomes after hip replacement
        surgery by continuous Pericapsular Nerve Group Block (PENG Block) in combination with lateral
        femoral cutaneous nerve (LFCN) block under the guidance of ultrasound.
  
        Methods: patients who had hip surgery at E University hospital, Hanoi, Vietnam from August
        2021 to August 2022 belonged to two groups: group of patients with pain relief with PENG
        block in combination with LFCN block (PENG BLOCK group) and group of patients with
        patient-controlled intravenous analgesia (PCA group). Outcomes regarding clinical and pain
        score from initiation of insertion or PCA insertion (H0) to after 72 hours (H72) were
        recorded.
  First, patients were explained about the study and asked to sign written informed consent if
        they agreed to participate in the study. Next, the patient was instructed to use the visual
        analogue scale (VAS) for pain score, as well as how to press the button to request pain
        relief. Then, a monitor was installed and operated to assess the clinical parameters
        (electrocardiogram, blood pressure, SpO2, arterial blood pressure, temperature). The patient
        was oxygenated 3-5 liters/minute and performed a peripheral intravenous line, with an 18G
        catheter, infused with 0.9% NaCl solution. Spinal anesthesia was administered with
        ropivacaine 0.5% and fentanyl.
  
        During and after the surgery, a group of patients received intravenous morphine analgesia via
        PCA (concentration 1mg/ml, bolus dose of 1mg, lock time 10 minutes, maximum dose 10mg/4
        hours). The remaining group of patients receive pain relief by PENG block and LFCN block. In
        this group, the ultrasound probe was placed horizontally from the anterior superior iliac
        spine, and was moved along the femoral arc defining the pubic spine. Then, the transducer was
        rotated 45 degrees, moved parallel to the femoral arch identifying the anterior inferior
        iliac spine (AIIS), iliopubic eminence (IPE) and inferior lumbosacral head. The ultrasound
        probe was moved lightly until the upper end of the femoral head was identified. Next, a 120
        mm Tuohy 18G anesthetic needle was used under ultrasound guidance, which was moved lateral to
        medial in the plane between the ultrasound transducer and the superior tip of the femoral
        head. Then, 10 mL of ropivacaine 0.25% was injected through the anesthetic needle tip.
  
        Data were collected at different times including: before surgery, before anesthesia, during
        surgery and after surgery. The information was recorded in the medical record.
  
        Preoperative data: the collected information included the general characteristics of the
        study patients including age, gender, weight, height, history of smoking/motion sickness,
        diagnosis, health classification according to ASA, liver and kidney function tests. With
        pre-anesthesia data, information was collected including pulse, blood pressure, respiratory
        rate, SpO2.
  
        Intraoperative data: the information collected includes information about anesthesia and
        surgical procedure.
  
        Post-operative data: the collected information includes blood test results (urea, creatinine,
        liver enzymes), pain score (Visual analogue scale - VAS - scale from 0 to 10, the higher the
        score, the higher the pain level. more), analgesic drugs consumption status, respiratory and
        circulatory changes, adverse events, and analgesic satisfaction. Time was recorded from
        initiation of catheterization or PCA insertion (H0) to after 72 hours (H72).
  allocation: Randomized
  intervention model: Parallel Assignment
  intervention model description: PCA group and PENG BLOCK group
  primary purpose: Supportive Care
  masking: Single (Participant)
  measure: VAS score at rest and on movement
  time frame: Time was recorded from initiation of catheterization or PCA insertion (H0) to after 72 hours (H72)
  description: the average VAS score (Visual Analogue Scale) at rest and on movement of both groups. The Visual Analogue Scale (VAS) measures pain intensity. The VAS consists of a 10cm line, with two end points representing 0 ('no pain') and 10 ('pain as bad as it could possibly be'). Ask the patient to rate their current level of pain by placing a mark on the line. Use a ruler to measure the distance in centimetres from the 'no pain marker' (or zero) to the current pain mark.
  measure: Side effects
  time frame: Time was recorded from initiation of catheterization or PCA insertion (H0) to after 72 hours (H72)
  description: Rate of vomitting/nausea, itchy, urinary retention, respiratory failure postoperative of both groups.
  arm group label: PENG BLOCK
  arm group type: Experimental
  description: receiving pain relief through PENG and LFCN block
  arm group label: PCA
  arm group type: Active Comparator
  description: receiving morphine PCA analgesia
  intervention type: Procedure
  intervention name: PERICAPSULAR NERVE GROUP BLOCK COMBINED WITH LATERAL FEMORAL CUTANEOUS NERVE BLOCK
  description: During and after the surgery, a group of patients received intravenous morphine analgesia via PCA (concentration 1mg/ml, bolus dose of 1mg, lock time 10 minutes, maximum dose 10mg/4 hours). The remaining group of patients receive pain relief by PENG block and LFCN block. In this group, the ultrasound probe was placed horizontally from the anterior superior iliac spine, and was moved along the femoral arc defining the pubic spine. Then, the transducer was rotated 45 degrees, moved parallel to the femoral arch identifying the anterior inferior iliac spine (AIIS), iliopubic eminence (IPE) and inferior lumbosacral head. The ultrasound probe was moved lightly until the upper end of the femoral head was identified. Next, a 120 mm Tuohy 18G anesthetic needle was used under ultrasound guidance, which was moved lateral to medial in the plane between the ultrasound transducer and the superior tip of the femoral head. Then, 10 mL of ropivacaine 0.25% was injected through the anesthetic needle tip
  arm group label: PCA
  arm group label: PENG BLOCK
  criteria: 
  gender: All
  minimum age: 18 Years
  maximum age: 80 Years
  healthy volunteers: No
  last name: Tu Nguyen, Professor
  role: Study Director
  affiliation: Hanoi Medical University
  facility: 
  country: Vietnam
  url: https://www.who.int/news-room/fact-sheets/detail/musculoskeletal-conditions
  description: Related Info
  citation: Ferguson RJ, Palmer AJ, Taylor A, Porter ML, Malchau H, Glyn-Jones S. Hip replacement. Lancet. 2018 Nov 3;392(10158):1662-1671. doi: 10.1016/S0140-6736(18)31777-X.
  PMID: 30496081
  citation: Ferrata P, Carta S, Fortina M, Scipio D, Riva A, Di Giacinto S. Painful hip arthroplasty: definition. Clin Cases Miner Bone Metab. 2011 May;8(2):19-22.
  PMID: 22461810
  citation: YaDeau JT, Tedore T, Goytizolo EA, Kim DH, Green DS, Westrick A, Fan R, Rade MC, Ranawat AS, Coleman SH, Kelly BT. Lumbar plexus blockade reduces pain after hip arthroscopy: a prospective randomized controlled trial. Anesth Analg. 2012 Oct;115(4):968-72. doi: 10.1213/ANE.0b013e318265bacd. Epub 2012 Jul 19.
  PMID: 22822195
  citation: Duarte LT, Beraldo PS, Saraiva RA. [Effects of epidural analgesia and continuous lumbar plexus block on functional rehabilitation after total hip arthroplasty]. Rev Bras Anestesiol. 2009 Sep-Oct;59(5):531-44. doi: 10.1016/s0034-7094(09)70078-9. Portuguese.
  PMID: 19784509
  citation: Singelyn FJ, Ferrant T, Malisse MF, Joris D. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous femoral nerve sheath block on rehabilitation after unilateral total-hip arthroplasty. Reg Anesth Pain Med. 2005 Sep-Oct;30(5):452-7. doi: 10.1016/j.rapm.2005.05.008.
  PMID: 16135349
  citation: Lin DY, Morrison C, Brown B, Saies AA, Pawar R, Vermeulen M, Anderson SR, Lee TS, Doornberg J, Kroon HM, Jaarsma RL. Pericapsular nerve group (PENG) block provides improved short-term analgesia compared with the femoral nerve block in hip fracture surgery: a single-center double-blinded randomized comparative trial. Reg Anesth Pain Med. 2021 May;46(5):398-403. doi: 10.1136/rapm-2020-102315. Epub 2021 Feb 26.
  PMID: 33637625
  citation: Shafiq F, Hamid M, Samad K. Complications and interventions associated with epidural analgesia for postoperative pain relief in a tertiary care hospital. Middle East J Anaesthesiol. 2010 Oct;20(6):827-32.
  PMID: 21526668
  citation: Rasouli MR, Viscusi ER. Adductor Canal Block for Knee Surgeries: An Emerging Analgesic Technique. Arch Bone Jt Surg. 2017 May;5(3):131-132. No abstract available.
  PMID: 28656158
  citation: Kamel I, Ahmed MF, Sethi A. Regional anesthesia for orthopedic procedures: What orthopedic surgeons need to know. World J Orthop. 2022 Jan 18;13(1):11-35. doi: 10.5312/wjo.v13.i1.11. eCollection 2022 Jan 18.
  PMID: 35096534
  responsible party type: Sponsor
  mesh term: Agnosia
  sharing ipd: Yes
  ipd description: We agree that all results and conclusion of this research will be used fully for other researchers
  ipd info type: Study Protocol
  ipd info type: Statistical Analysis Plan (SAP)
  ipd info type: Informed Consent Form (ICF)
  ipd info type: Clinical Study Report (CSR)
  ipd info type: Analytic Code
  ipd time frame: from September 2023 to the unidentified time
  ipd access criteria: anesthesiologists, surgeons all over the world