xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT06018077</url>
    </required_header>
    <id_info>
      <org_study_id>GO22/297</org_study_id>
      <nct_id>NCT06018077</nct_id>
    </id_info>
    <brief_title>Chemerin in Colorectal Cancer and Its Relationship With Diet Quality</brief_title>
    <official_title>Investıgatıon of The Relatıonshıps Between Serum Chemerın Levels, Dıet Qualıty, Inflammatory and Phytochemıcal Indıces in Adults wıth Colorectal Cancer</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>Hacettepe University</agency>
        <agency_class>Other</agency_class>
      </lead_sponsor>
      <collaborator>
        <agency>Ankara Bilkent City Hospital</agency>
        <agency_class>Other</agency_class>
      </collaborator>
    </sponsors>
    <source>Hacettepe University</source>
    <oversight_info>
      <has_dmc>No</has_dmc>
      <is_fda_regulated_drug>No</is_fda_regulated_drug>
      <is_fda_regulated_device>No</is_fda_regulated_device>
    </oversight_info>
    <brief_summary>
      <textblock>
        To investigate the relationship between serum chemerin levels of individuals with colorectal&#xD;
        cancer and systematic inflammatory response parameters such as C-reactive protein(CRP) and&#xD;
        albumin, and to investigate the relationship of these biomarkers with dietary inflammatory&#xD;
        index, phytochemical, anthropometric measurements, and dietary inflammatory index, which is&#xD;
        calculated with the data obtained from the 24-hour food consumption record and food&#xD;
        consumption frequency questionnaire. The aim of this study is to examine the relationships&#xD;
        between the index and dietary antioxidant capacity and to compare them with those of healthy&#xD;
        individuals.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        The research will be executed. with 52 adult individuals between the ages of 18-65 who&#xD;
        applied to the Ankara City Hospital Oncology Hospital Medical Oncology outpatient clinic,&#xD;
        newly diagnosed with colorectal cancer (except for Stage IV), and 52 healthy adult&#xD;
        individuals without any chronic disease, matched for age, gender, and BMI. Individuals will&#xD;
        be told about the study in detail and those who accept will be included in the study by&#xD;
        signing an informed consent form. A data collection form containing health and demographic&#xD;
        information will be applied to the participants; Then, after 8-12 hours of fasting, body&#xD;
        composition analysis (body fat ratio, muscle ratio, visceral fat level, resting metabolic&#xD;
        rate) will be performed with the Omron BF511, a body composition analysis scale that works&#xD;
        with the bioelectrical impedance method, and within the scope of anthropometric measurements,&#xD;
        body weight, height length, BMI measurements will be taken. Body mass index (BMI) will be&#xD;
        obtained by dividing the body weight (kg) by the square of the height in meters. After 8-12&#xD;
        hours of fasting, 5 ml of venous blood will be taken from the participants by the nurses of&#xD;
        the Medical Oncology Clinic, and the serum obtained after centrifugation will be analyzed in&#xD;
        accordance with the manufacturer's kit protocols and in duplicate, the C-reactive protein&#xD;
        (CRP) level will be analyzed by the immunoturbidimetric method and the albumin Bromocresol&#xD;
        Green-Dye binding method, and chemerin level by enzyme-linked immunoassay (ELISA) method.&#xD;
        Nutritional status of individuals will be evaluated with a 24-hour retrospective food&#xD;
        consumption record and food consumption frequency questionnaire, and dietary inflammatory&#xD;
        index, phytochemical index, and dietary antioxidant capacity will be calculated from the&#xD;
        obtained records. In order to measure the inflammatory potential of the diet, the Dietary&#xD;
        Inflammatory Index (DII) was developed based on the pro-inflammatory and anti-inflammatory&#xD;
        effects of different dietary components on various inflammatory biomarkers. The&#xD;
        &quot;Phytochemical Index&quot; method was used to calculate the total phytochemical intake from the&#xD;
        diet. The total antioxidant capacity of the diet was calculated using data obtained from&#xD;
        dietary intake records based on Ferric Reducing Ability of Plasma (FRAP) methods.&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Recruiting</overall_status>
    <start_date type="Actual">October 15, 2022</start_date>
    <completion_date type="Anticipated">August 31, 2025</completion_date>
    <primary_completion_date type="Anticipated">June 15, 2024</primary_completion_date>
    <study_type>Observational [Patient Registry]</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <observational_model>Case-Control</observational_model>
      <time_perspective>Cross-Sectional</time_perspective>
    </study_design_info>
    <target_duration>1 Day</target_duration>
    <primary_outcome>
      <measure>Serum chemerin level</measure>
      <time_frame>12 months</time_frame>
      <description>The blood obtained from individuals after 8-12 hours of fasting will be analyzed in duplicate with the enzyme-linked immunity test (ELISA) method from the serum obtained after centrifugation, in accordance with the manufacturer's kit protocols.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Body weight</measure>
      <time_frame>12 months</time_frame>
      <description>The body weights of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Body fat percentage</measure>
      <time_frame>12 months</time_frame>
      <description>The body fat percentage of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Body muscle percentage</measure>
      <time_frame>12 months</time_frame>
      <description>The body muscle percentage of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Visseral fat level</measure>
      <time_frame>12 months</time_frame>
      <description>The visseral fat level of the individuals will be measured by using Omron BF511 brand bioelectrical impedance device while they are on an empty stomach and wearing light clothes without metal objects.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Serum albumin level</measure>
      <time_frame>12 months</time_frame>
      <description>The blood obtained from individuals after 8-12 hours of fasting will be analyzed from the serum obtained after centrifugation, in duplicate using the Bromocresol Green-Dye binding method, in accordance with the manufacturer's kit protocols.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Serum C-reaktive protein (CRP)</measure>
      <time_frame>12 months</time_frame>
      <description>The blood obtained from individuals after 8-12 hours of fasting will be analyzed in duplicate with the immunoturbidimetric method from the serum obtained after centrifugation, in accordance with the manufacturer's kit protocols.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Body Mass Index (BMI)</measure>
      <time_frame>12 months</time_frame>
      <description>Body mass index (BMI) will be obtained by dividing the body weight (kg) by the square of the height in meters.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Resting Metabolic Rate (RMR)</measure>
      <time_frame>12 months</time_frame>
      <description>The resting metabolic rate of the individuals will be measured by using Omron BF511 brand bioelectrical impedance device while they are on an empty stomach and wearing light clothes without metal objects.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Dietary Phytochemical Index (DPI)</measure>
      <time_frame>12 months</time_frame>
      <description>he &quot;Phytochemical Index&quot; method was used to calculate the total phytochemical intake from the diet. The ratio of the total amount of phytochemical rich foods in the diet in grams per day to the total food intake (g/day) will be calculated as follows. The amount of phytochemicals contained in each food will be obtained from the USDA database.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Dietary Inflammatory Index (DII)</measure>
      <time_frame>12 months</time_frame>
      <description>The frequency of food consumption from the participants and the data to be obtained from the twenty-four hour retrospective food consumption record will be evaluated using the Computer Aided Nutrition Program Nutrition Information System (BeBIS 9.0). &quot;Diet inflammatory index&quot; will be calculated by multiplying the nutritional parameters obtained from the recordings with the &quot;inflammatory effect score&quot;.The resulting values are summed to obtain the dietary inflammatory index (DII) score, which represents the inflammatory load of the individual's daily diet.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Dİetary Total Antioxidant Capacity (DTAC)</measure>
      <time_frame>12 months</time_frame>
      <description>Dietary total antioxidant capacity will be determined using the 'Antioxidant Food Database'. The FRAP value of that food will be calculated by multiplying the reported iron reducing antioxidant power (FRAP) value for each food and the grams of the daily average consumed food. The total antioxidant capacity (TAK) of the diet will be calculated by summing the calculated FRAP values of all foods and expressed as mmol/100 g nutrient.</description>
    </primary_outcome>
    <number_of_groups>2</number_of_groups>
    <enrollment type="Anticipated">104</enrollment>
    <condition>Colorectal Cancer</condition>
    <condition>Diet, Healthy</condition>
    <condition>Diet Habit</condition>
    <condition>Nutrition Aspect of Cancer</condition>
    <condition>Inflammation</condition>
    <arm_group>
      <arm_group_label>Colorectal Cancer Group</arm_group_label>
      <description>Individuals aged 18-65 years, who applied to Ankara City Hospital Oncology Hospital Medical Oncology Outpatient Clinic, newly diagnosed with colorectal cancer as a result of the necessary examinations, at least 3 weeks after the surgical procedure and without metastasis (except for Stage IV)</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Healthy Group</arm_group_label>
      <description>A healthy adult between the ages of 18-65 who has not been diagnosed with any malignant disease and consented to participate in the study.</description>
    </arm_group>
    <intervention>
      <intervention_type>Behavioral</intervention_type>
      <intervention_name>Dietary İntake, Biochemical parameters, Antropometric measuruments</intervention_name>
      <description>Nutritional status of individuals will be evaluated with a 24-hour retrospective food consumption record and food consumption frequency questionnaire. After 8-12 hours of fasting, body composition analysis will be performed and within the scope of anthropometric measurements, body weight, height length, BMI measurements will be taken. Then, venous blood will be taken from the participants C-reactive protein (CRP), albumin and chemerin level will be analyzed.</description>
      <arm_group_label>Colorectal Cancer Group</arm_group_label>
      <arm_group_label>Healthy Group</arm_group_label>
      <other_name>Food Frequency Questionnaire and Dietary Record</other_name>
      <other_name>Blood Sample</other_name>
      <other_name>Antropometric measurements (body weight, height, body fat rate, muscle rate, resting metabolic rate)</other_name>
    </intervention>
    <biospec_retention>Samples With DNA</biospec_retention>
    <biospec_descr>
      <textblock>
        1 tube of blood sample is centrifuged and serum is taken.&#xD;
      </textblock>
    </biospec_descr>
    <eligibility>
      <study_pop>
        <textblock>
          After the necessary tests are made by the doctor of Ankara City Hospital Oncology Hospital&#xD;
          Medical Oncology Polyclinic, individuals diagnosed as colorectal in the patient group, and&#xD;
          those evaluated as healthy in the control group and meet the eligibility criteria will be&#xD;
          included.&#xD;
        </textblock>
      </study_pop>
      <sampling_method>Non-Probability Sample</sampling_method>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
          For patient group&#xD;
  &#xD;
            -  Between the ages of 18-65,&#xD;
  &#xD;
            -  At least 3 weeks after surgery&#xD;
  &#xD;
            -  Individuals newly diagnosed with colorectal cancer by a oncolog (except for Stage IV)&#xD;
  &#xD;
          For healthy group&#xD;
  &#xD;
            -  Between the ages of 18-65,&#xD;
  &#xD;
            -  Healthy adult individuals without any chronic disease&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
          For patient group&#xD;
  &#xD;
            -  Receiving active radiotherapy or chemotherapy,&#xD;
  &#xD;
            -  Existing history of metastasis,&#xD;
  &#xD;
            -  Having a malignant disease other than the diagnosis of colorectal cancer, - History of&#xD;
               metabolic syndrome, cardiovascular disease, hepatic disease, chronic kidney disease,&#xD;
               major hormonal or hematological disease, pulmonary disease,&#xD;
  &#xD;
            -  With a history of autoimmune disease, with a history of inflammatory diseases&#xD;
               (pancreatitis, chron's, ulcerative colitis, etc.),&#xD;
  &#xD;
            -  Those who use nonsteroidal anti-inflammatory drugs (NSAIDs),&#xD;
  &#xD;
            -  Alcoholic and other drug addicts,&#xD;
  &#xD;
            -  Smokers,&#xD;
  &#xD;
            -  Those with mental disorders (major depressive disorder, dementia),&#xD;
  &#xD;
            -  Those who take corticosteroid or hormone therapy,&#xD;
  &#xD;
            -  Those who have an existing infectious disease, those who receive medical nutrition&#xD;
               therapy for any disease&#xD;
  &#xD;
          For healthy group&#xD;
  &#xD;
            -  Individuals aged 18 and under and 65 years and older,&#xD;
  &#xD;
            -  History of metabolic syndrome, cardiovascular disease, hepatic disease, chronic kidney&#xD;
               disease, major hormonal or hematological disease, pulmonary disease,&#xD;
  &#xD;
            -  With a history of autoimmune disease, with a history of inflammatory diseases&#xD;
               (pancreatitis, chron's, ulcerative colitis, etc.),&#xD;
  &#xD;
            -  Those who use nonsteroidal anti-inflammatory drugs (NSAIDs),&#xD;
  &#xD;
            -  Pregnant and lactating women,&#xD;
  &#xD;
            -  Alcoholic and other drug addicts,&#xD;
  &#xD;
            -  Smokers, those with mental disorders (major depressive disorder, dementia),&#xD;
  &#xD;
            -  Those taking corticosteroid or hormone therapy,&#xD;
  &#xD;
            -  Those with existing infectious disease,&#xD;
  &#xD;
            -  Those receiving medical nutrition therapy for any illness&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>19 Years</minimum_age>
      <maximum_age>64 Years</maximum_age>
      <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
    </eligibility>
    <overall_official>
      <last_name>Semra Bakir Angay</last_name>
      <role>Principal Investigator</role>
      <affiliation>Hacettepe University</affiliation>
    </overall_official>
    <overall_official>
      <last_name>Aylin Acikgoz Pinar</last_name>
      <role>Principal Investigator</role>
      <affiliation>Hacettepe University</affiliation>
    </overall_official>
    <overall_contact>
      <last_name>Semra Bakir Angay</last_name>
      <phone>+903123051094</phone>
      <phone_ext>151</phone_ext>
      <email>semrabakir@hacettepe.edu.tr</email>
    </overall_contact>
    <overall_contact_backup>
      <last_name>Aylin Acikgoz Pinar</last_name>
      <phone>903123051094</phone>
    </overall_contact_backup>
    <location>
      <facility>
        <name>Hacettepe University Health Science Faculty, Nutrition and Dietetic Department</name>
        <address>
          <city>Ankara</city>
          <zip>06280</zip>
          <country>Turkey</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Semra Bakir Angay</last_name>
        <phone>+90 312 305 10 94</phone>
        <phone_ext>151</phone_ext>
        <email>semrabakir@hacettepe.edu.tr</email>
      </contact>
      <contact_backup>
        <last_name>Aylin Acikgoz Pinar, PhD</last_name>
        <phone>+90 312 305 10 94</phone>
        <phone_ext>127</phone_ext>
        <email>aylinn@hacettepe.edu.tr</email>
      </contact_backup>
    </location>
    <location>
      <facility>
        <name>Ankara Bilkent City Hospital, Oncology Hospital, Medical Oncology Outpatient Clinic</name>
        <address>
          <city>Ankara</city>
          <zip>06800</zip>
          <country>Turkey</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Mehmet Ali Nahit Sendur, Prof</last_name>
        <phone>+90 312 552 60 00</phone>
      </contact>
      <contact_backup>
        <last_name>Semra Bakir Angay</last_name>
        <phone>+90 312 305 10 94</phone>
        <phone_ext>151</phone_ext>
      </contact_backup>
    </location>
    <location_countries>
      <country>Turkey</country>
    </location_countries>
    <verification_date>August 2023</verification_date>
    <study_first_submitted>August 25, 2023</study_first_submitted>
    <study_first_submitted_qc>August 25, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">August 30, 2023</study_first_posted>
    <last_update_submitted>August 25, 2023</last_update_submitted>
    <last_update_submitted_qc>August 25, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">August 30, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Principal Investigator</responsible_party_type>
      <investigator_affiliation>Hacettepe University</investigator_affiliation>
      <investigator_full_name>Semra Bakir Angay</investigator_full_name>
      <investigator_title>Principal Investigator</investigator_title>
    </responsible_party>
    <keyword>Colorectal cancer</keyword>
    <keyword>Dietary inflammatory index</keyword>
    <keyword>Dietary phytochemical index</keyword>
    <keyword>Chemerin</keyword>
    <keyword>Dietary total antioxidant capacity</keyword>
    <condition_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Colorectal Neoplasms</mesh_term>
      <mesh_term>Inflammation</mesh_term>
    </condition_browse>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT06018077
  org study id: GO22/297
  nct id: NCT06018077
  lead sponsor: 
  collaborator: 
  has dmc: No
  is fda regulated drug: No
  is fda regulated device: No
  To investigate the relationship between serum chemerin levels of individuals with colorectal
        cancer and systematic inflammatory response parameters such as C-reactive protein(CRP) and
        albumin, and to investigate the relationship of these biomarkers with dietary inflammatory
        index, phytochemical, anthropometric measurements, and dietary inflammatory index, which is
        calculated with the data obtained from the 24-hour food consumption record and food
        consumption frequency questionnaire. The aim of this study is to examine the relationships
        between the index and dietary antioxidant capacity and to compare them with those of healthy
        individuals.
  The research will be executed. with 52 adult individuals between the ages of 18-65 who
        applied to the Ankara City Hospital Oncology Hospital Medical Oncology outpatient clinic,
        newly diagnosed with colorectal cancer (except for Stage IV), and 52 healthy adult
        individuals without any chronic disease, matched for age, gender, and BMI. Individuals will
        be told about the study in detail and those who accept will be included in the study by
        signing an informed consent form. A data collection form containing health and demographic
        information will be applied to the participants; Then, after 8-12 hours of fasting, body
        composition analysis (body fat ratio, muscle ratio, visceral fat level, resting metabolic
        rate) will be performed with the Omron BF511, a body composition analysis scale that works
        with the bioelectrical impedance method, and within the scope of anthropometric measurements,
        body weight, height length, BMI measurements will be taken. Body mass index (BMI) will be
        obtained by dividing the body weight (kg) by the square of the height in meters. After 8-12
        hours of fasting, 5 ml of venous blood will be taken from the participants by the nurses of
        the Medical Oncology Clinic, and the serum obtained after centrifugation will be analyzed in
        accordance with the manufacturer's kit protocols and in duplicate, the C-reactive protein
        (CRP) level will be analyzed by the immunoturbidimetric method and the albumin Bromocresol
        Green-Dye binding method, and chemerin level by enzyme-linked immunoassay (ELISA) method.
        Nutritional status of individuals will be evaluated with a 24-hour retrospective food
        consumption record and food consumption frequency questionnaire, and dietary inflammatory
        index, phytochemical index, and dietary antioxidant capacity will be calculated from the
        obtained records. In order to measure the inflammatory potential of the diet, the Dietary
        Inflammatory Index (DII) was developed based on the pro-inflammatory and anti-inflammatory
        effects of different dietary components on various inflammatory biomarkers. The
        "Phytochemical Index" method was used to calculate the total phytochemical intake from the
        diet. The total antioxidant capacity of the diet was calculated using data obtained from
        dietary intake records based on Ferric Reducing Ability of Plasma (FRAP) methods.
  observational model: Case-Control
  time perspective: Cross-Sectional
  measure: Serum chemerin level
  time frame: 12 months
  description: The blood obtained from individuals after 8-12 hours of fasting will be analyzed in duplicate with the enzyme-linked immunity test (ELISA) method from the serum obtained after centrifugation, in accordance with the manufacturer's kit protocols.
  measure: Body weight
  time frame: 12 months
  description: The body weights of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.
  measure: Body fat percentage
  time frame: 12 months
  description: The body fat percentage of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.
  measure: Body muscle percentage
  time frame: 12 months
  description: The body muscle percentage of the individuals will be measured after 8-12 hours of fasting, using Omron BF511 brand bioelectrical impedance device, wearing light clothes without metal objects.
  measure: Visseral fat level
  time frame: 12 months
  description: The visseral fat level of the individuals will be measured by using Omron BF511 brand bioelectrical impedance device while they are on an empty stomach and wearing light clothes without metal objects.
  measure: Serum albumin level
  time frame: 12 months
  description: The blood obtained from individuals after 8-12 hours of fasting will be analyzed from the serum obtained after centrifugation, in duplicate using the Bromocresol Green-Dye binding method, in accordance with the manufacturer's kit protocols.
  measure: Serum C-reaktive protein (CRP)
  time frame: 12 months
  description: The blood obtained from individuals after 8-12 hours of fasting will be analyzed in duplicate with the immunoturbidimetric method from the serum obtained after centrifugation, in accordance with the manufacturer's kit protocols.
  measure: Body Mass Index (BMI)
  time frame: 12 months
  description: Body mass index (BMI) will be obtained by dividing the body weight (kg) by the square of the height in meters.
  measure: Resting Metabolic Rate (RMR)
  time frame: 12 months
  description: The resting metabolic rate of the individuals will be measured by using Omron BF511 brand bioelectrical impedance device while they are on an empty stomach and wearing light clothes without metal objects.
  measure: Dietary Phytochemical Index (DPI)
  time frame: 12 months
  description: he "Phytochemical Index" method was used to calculate the total phytochemical intake from the diet. The ratio of the total amount of phytochemical rich foods in the diet in grams per day to the total food intake (g/day) will be calculated as follows. The amount of phytochemicals contained in each food will be obtained from the USDA database.
  measure: Dietary Inflammatory Index (DII)
  time frame: 12 months
  description: The frequency of food consumption from the participants and the data to be obtained from the twenty-four hour retrospective food consumption record will be evaluated using the Computer Aided Nutrition Program Nutrition Information System (BeBIS 9.0). "Diet inflammatory index" will be calculated by multiplying the nutritional parameters obtained from the recordings with the "inflammatory effect score".The resulting values are summed to obtain the dietary inflammatory index (DII) score, which represents the inflammatory load of the individual's daily diet.
  measure: Dİetary Total Antioxidant Capacity (DTAC)
  time frame: 12 months
  description: Dietary total antioxidant capacity will be determined using the 'Antioxidant Food Database'. The FRAP value of that food will be calculated by multiplying the reported iron reducing antioxidant power (FRAP) value for each food and the grams of the daily average consumed food. The total antioxidant capacity (TAK) of the diet will be calculated by summing the calculated FRAP values of all foods and expressed as mmol/100 g nutrient.
  arm group label: Colorectal Cancer Group
  description: Individuals aged 18-65 years, who applied to Ankara City Hospital Oncology Hospital Medical Oncology Outpatient Clinic, newly diagnosed with colorectal cancer as a result of the necessary examinations, at least 3 weeks after the surgical procedure and without metastasis (except for Stage IV)
  arm group label: Healthy Group
  description: A healthy adult between the ages of 18-65 who has not been diagnosed with any malignant disease and consented to participate in the study.
  intervention type: Behavioral
  intervention name: Dietary İntake, Biochemical parameters, Antropometric measuruments
  description: Nutritional status of individuals will be evaluated with a 24-hour retrospective food consumption record and food consumption frequency questionnaire. After 8-12 hours of fasting, body composition analysis will be performed and within the scope of anthropometric measurements, body weight, height length, BMI measurements will be taken. Then, venous blood will be taken from the participants C-reactive protein (CRP), albumin and chemerin level will be analyzed.
  arm group label: Colorectal Cancer Group
  arm group label: Healthy Group
  other name: Food Frequency Questionnaire and Dietary Record
  other name: Blood Sample
  other name: Antropometric measurements (body weight, height, body fat rate, muscle rate, resting metabolic rate)
  1 tube of blood sample is centrifuged and serum is taken.
  study pop: 
  sampling method: Non-Probability Sample
  criteria: 
  gender: All
  minimum age: 19 Years
  maximum age: 64 Years
  healthy volunteers: Accepts Healthy Volunteers
  last name: Semra Bakir Angay
  role: Principal Investigator
  affiliation: Hacettepe University
  last name: Aylin Acikgoz Pinar
  role: Principal Investigator
  affiliation: Hacettepe University
  last name: Semra Bakir Angay
  phone: +903123051094
  phone ext: 151
  email: semrabakir@hacettepe.edu.tr
  last name: Aylin Acikgoz Pinar
  phone: 903123051094
  facility: 
  status: Recruiting
  contact: 
  contact backup: 
  facility: 
  status: Recruiting
  contact: 
  contact backup: 
  country: Turkey
  responsible party type: Principal Investigator
  investigator affiliation: Hacettepe University
  investigator full name: Semra Bakir Angay
  investigator title: Principal Investigator
  mesh term: Colorectal Neoplasms
  mesh term: Inflammation