xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT06035692</url>
    </required_header>
    <id_info>
      <org_study_id>BPB</org_study_id>
      <nct_id>NCT06035692</nct_id>
    </id_info>
    <brief_title>Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach</brief_title>
    <acronym>ABPBCAETRA</acronym>
    <official_title>The Protective Effect of Brachial Plexus Block on Upper Limb Vascular Injury in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>The First Affiliated Hospital with Nanjing Medical University</agency>
        <agency_class>Other</agency_class>
      </lead_sponsor>
      <collaborator>
        <agency>Xuzhou Central Hospital</agency>
        <agency_class>Other</agency_class>
      </collaborator>
      <collaborator>
        <agency>Huizhou Municipal Central Hospital</agency>
        <agency_class>Other</agency_class>
      </collaborator>
      <collaborator>
        <agency>The First People's Hospital of Changzhou</agency>
        <agency_class>Other</agency_class>
      </collaborator>
      <collaborator>
        <agency>Nanjing Jiangbei Hospital</agency>
        <agency_class>Other</agency_class>
      </collaborator>
    </sponsors>
    <source>The First Affiliated Hospital with Nanjing Medical University</source>
    <oversight_info>
      <has_dmc>Yes</has_dmc>
      <is_fda_regulated_drug>No</is_fda_regulated_drug>
      <is_fda_regulated_device>No</is_fda_regulated_device>
    </oversight_info>
    <brief_summary>
      <textblock>
        The aim of this study was to investigate the feasibility and mechanism of brachial plexus&#xD;
        block(BPB) preconditioning in preventing upper limb vascular injury in patients undergoing&#xD;
        interventional surgery for intracranial aneurysms via transradial access(TRA). A multicenter&#xD;
        prospective clinical trial was designed. The study subjects were patients undergoing cerebral&#xD;
        aneurysm embolization with TRA. BPB was given in the experimental group patients and no BPB&#xD;
        in the control group. To evaluate the short and long-term protective effects of brachial&#xD;
        plexus block on the upper limb blood vessels injury after operation, the upper limb vasospasm&#xD;
        and hemodynamic changes during operation, upper limb vascular thrombosis and radial artery&#xD;
        occlusion after operation were observed in the two groups.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        The aim of this study was to investigate the feasibility and mechanism of BPB preconditioning&#xD;
        in preventing upper limb vascular injury in patients undergoing interventional surgery for&#xD;
        intracranial aneurysms viaTRA. A multicenter prospective clinical trial was designed, and the&#xD;
        study subjects were patients undergoing cerebral aneurysm embolization with TRA. The&#xD;
        experimental group was givenBPB, and the control group was not given BPB.Firstly, the minimum&#xD;
        effective concentration (MEC50 and MEC95) of BPB for preventing radial artery spasm was&#xD;
        determined by sequential method. Then the experimental group patients was treated with&#xD;
        MEC95.The hemodynamic changes and spasm of the upper limb vessels during the operation, and&#xD;
        the complications such as thrombosis of the upper limb vessels and radial artery occlusion&#xD;
        after the operation were compared between the two groups, to evaluate the short-term and&#xD;
        long-term protective effects of BPB on upper limb vascular injury in those patients.The&#xD;
        content of IL-2,IL-4,IL-6,IL-10,IL-17,IL-12p70,IFN-γ,TNF-α in plasma was determined by flow&#xD;
        immunofluorescence before and after operation, to compare the changes of inflammatory&#xD;
        cytokines between the two groups.&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Recruiting</overall_status>
    <start_date type="Actual">June 1, 2023</start_date>
    <completion_date type="Anticipated">June 30, 2024</completion_date>
    <primary_completion_date type="Anticipated">December 31, 2023</primary_completion_date>
    <phase>N/A</phase>
    <study_type>Interventional</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <allocation>Randomized</allocation>
      <intervention_model>Parallel Assignment</intervention_model>
      <intervention_model_description>This is a multicenter prospective randomized controlled study.Patients were assigned to the two groups with the use of central randomization and competitive enrollment. The experimental group was given brachial plexus block 30 minutes before surgery, and the control group was given routine treatment.</intervention_model_description>
      <primary_purpose>Prevention</primary_purpose>
      <masking>Triple (Participant, Investigator, Outcomes Assessor)</masking>
      <masking_description>In this study, participants, data recorders(investigators), and outcome assessor were unaware of group assignments</masking_description>
    </study_design_info>
    <primary_outcome>
      <measure>Assess the degree of vasospasm in the upper extremity artery by angiography</measure>
      <time_frame>During the operation</time_frame>
      <description>The degree of vasospasm in the upper extremity artery was assessed by angiography during surgery.</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Assessed thrombosis in the upper extremity artery by ultrasound</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>Upper extremity artery thrombosis was assessed by ultrasonography after surgery</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Assessed stenosis in the upper extremity artery by ultrasound</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>Upper extremity artery stenosis was assessed by ultrasonography after surgery</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Assessed occlusion in the upper extremity artery by ultrasound</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>Upper extremity artery occlusion was assessed by ultrasonography after surgery</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Assess occlusion in the upper extremity artery by angiography or ultrasonography</measure>
      <time_frame>Month 1 after surgery</time_frame>
      <description>Upper extremity artery occlusion was assessed by angiography or ultrasonography after surgery</description>
    </primary_outcome>
    <secondary_outcome>
      <measure>Evaluate the hemodynamic changes of upper limb artery by ultrasound</measure>
      <time_frame>Before the operation</time_frame>
      <description>The hemodynamic changes of upper limb artery were evaluated by ultrasound after BPB , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent(%).</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Evaluate the hemodynamic changes of upper limb vessels by ultrasound</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>The hemodynamic changes of upper limb vessels were evaluated by ultrasound after BPB. , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent (%).</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Recorded the changes of inflammatory cytokine IL-6 in plasma before and after operation.</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>The changes of inflammatory cytokine IL-6 in plasma were recorded beforeand after operation by Flow immunofluorescence assay.</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Recorded the changes of inflammatory cytokine IL-10 in plasma before and after operation.</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>The changes of inflammatory cytokine IL-10 in plasma were recorded beforeand after operation by Flow immunofluorescence assay.</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Evaluated the incidence of postoperative cerebral infarction by magnetic resonance imagingoperation(MRI)</measure>
      <time_frame>Day 1 after surgery</time_frame>
      <description>The incidence of postoperative cerebral infarction was evaluated by MRI，Including lacunar cerebral infarction.</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Evaluate the hemodynamic changes of upper limb vessels by ultrasound</measure>
      <time_frame>Month 1 after the surgery</time_frame>
      <description>The hemodynamic changes of upper limb vessels were evaluated by ultrasound after BPB. , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent (%).</description>
    </secondary_outcome>
    <other_outcome>
      <measure>Calculate MEC50 and MEC95 of ropivacaine in brachial plexus block by sequential method</measure>
      <time_frame>During the operation</time_frame>
      <description>The minimum effective concentration（MEC50 and MEC95） of ropivacaine for brachial plexus block to prevent radial artery spasm during operation was determined by sequential method.</description>
    </other_outcome>
    <other_outcome>
      <measure>Record VAS score by questionnaire after the surgery</measure>
      <time_frame>Day 0 after the surgery</time_frame>
      <description>VAS score was record by questionnaire.The VAS was scored from 0 to 10, with 0 indicating no pain and 10 indicating severe and unbearable pain. The pain scores of patients were recorded after awakening.</description>
    </other_outcome>
    <other_outcome>
      <measure>Record VAS score by questionnaire 24h after the surgery</measure>
      <time_frame>Day 1 after the surgery</time_frame>
      <description>VAS score was record by questionnaire.The VAS was scored from 0 to 10, with 0 indicating no pain and 10 indicating severe and unbearable pain. The pain scores of patients were recorded 1 day after operation</description>
    </other_outcome>
    <other_outcome>
      <measure>Record physician satisfaction by questionnaire</measure>
      <time_frame>Day 0 after the surgery</time_frame>
      <description>Physician satisfaction was scored on a scale of 1-5, with a score of 1 indicating very poor and dissatisfied experience and a score of 5 indicating very satisfied. The surgeons were asked to fill in the satisfaction questionnaire according to the operation situation after operation and recorded.</description>
    </other_outcome>
    <other_outcome>
      <measure>Record complications of brachial plexus block</measure>
      <time_frame>Day 1 after the surgery</time_frame>
      <description>The complications of brachial plexus block such as hematoma, infection, nerve injury were recorded after the surgery.</description>
    </other_outcome>
    <number_of_arms>2</number_of_arms>
    <enrollment type="Anticipated">120</enrollment>
    <condition>Intracranial Aneurysm</condition>
    <condition>Transradial Access(TRA)</condition>
    <arm_group>
      <arm_group_label>Brachial plexus block group（Group T）</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>All patients received brachial plexus block 30min before surgery</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Control group （Group C）</arm_group_label>
      <arm_group_type>No Intervention</arm_group_type>
      <description>All patients were not pretreated with brachial plexus block before operation</description>
    </arm_group>
    <intervention>
      <intervention_type>Drug</intervention_type>
      <intervention_name>Ropivacaine</intervention_name>
      <description>The MEC50 and MEC95 of ropivacaine for brachial plexus block was measured by sequential method, and then the patients in the experimental group were treated with MEC95.</description>
      <arm_group_label>Brachial plexus block group（Group T）</arm_group_label>
      <other_name>brachial plexus block</other_name>
    </intervention>
    <eligibility>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
            -  18-75 years old, BMI&lt;28kg/m2&#xD;
  &#xD;
            -  ASA physical status Ⅰ-Ⅲ&#xD;
  &#xD;
            -  Elective interventional surgery for intracranial aneurysms via TRA&#xD;
  &#xD;
            -  willing to sign informed consent&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
            -  patients allergic to local anesthetics&#xD;
  &#xD;
            -  neck infection on the surgical side&#xD;
  &#xD;
            -  Preoperative upper extremity ultrasound or DSA showed radial artery occlusion and&#xD;
               arteriovenous fistula&#xD;
  &#xD;
            -  The diameter of radial artery was still less than 2mm after brachial plexus block&#xD;
  &#xD;
            -  Axillary artery occlusion and other vascular anatomical abnormalities may affect the&#xD;
               operation&#xD;
  &#xD;
            -  Radial artery patency: Barbeau type D&#xD;
  &#xD;
            -  The history of hand trauma may affect the establishment of radial artery; access, or&#xD;
               the use of radial artery as a bypass or dialysis vessel&#xD;
  &#xD;
            -  patients with incomplete block effect after nerve block were detected;&#xD;
  &#xD;
            -  The patient refused to participate in the study or cooperate with the follow-up&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>18 Years</minimum_age>
      <maximum_age>75 Years</maximum_age>
      <healthy_volunteers>No</healthy_volunteers>
    </eligibility>
    <overall_official>
      <last_name>Jingjin Li, MD</last_name>
      <role>Principal Investigator</role>
      <affiliation>The First Affiliated Hospital with Nanjing Medical University</affiliation>
    </overall_official>
    <overall_contact>
      <last_name>Feng Feng, Master</last_name>
      <phone>13814073686</phone>
      <email>316637881@qq.com</email>
    </overall_contact>
    <overall_contact_backup>
      <last_name>Nan Li, Master</last_name>
      <phone>15850647102</phone>
      <email>mzlinan2010@163.com</email>
    </overall_contact_backup>
    <location>
      <facility>
        <name>The First Affiliated Hospital with Nanjing Medical University</name>
        <address>
          <city>Nanjing</city>
          <state>Jiangsu</state>
          <zip>210029</zip>
          <country>China</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Feng Feng, Master</last_name>
        <phone>13814073686</phone>
        <email>316637881@qq.com</email>
      </contact>
      <contact_backup>
        <last_name>Nan Li, Master</last_name>
        <phone>15850647102</phone>
        <email>mzlinan2010@163.com</email>
      </contact_backup>
      <investigator>
        <last_name>Jingjin Li, MD</last_name>
        <role>Principal Investigator</role>
      </investigator>
    </location>
    <location_countries>
      <country>China</country>
    </location_countries>
    <verification_date>September 2023</verification_date>
    <study_first_submitted>June 27, 2023</study_first_submitted>
    <study_first_submitted_qc>September 11, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">September 13, 2023</study_first_posted>
    <last_update_submitted>September 11, 2023</last_update_submitted>
    <last_update_submitted_qc>September 11, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">September 13, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Sponsor</responsible_party_type>
    </responsible_party>
    <condition_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Intracranial Aneurysm</mesh_term>
      <mesh_term>Aneurysm</mesh_term>
    </condition_browse>
    <intervention_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Ropivacaine</mesh_term>
    </intervention_browse>
    <patient_data>
      <sharing_ipd>Yes</sharing_ipd>
      <ipd_description>If anyone is interested in this study, please contact us, and I think we would like to share IPD with him</ipd_description>
      <ipd_info_type>Study Protocol</ipd_info_type>
      <ipd_info_type>Clinical Study Report (CSR)</ipd_info_type>
      <ipd_time_frame>Month 1</ipd_time_frame>
      <ipd_access_criteria>If anyone is interested in this study, please contact us, and I think we would like to share IPD with him</ipd_access_criteria>
    </patient_data>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT06035692
  org study id: BPB
  nct id: NCT06035692
  lead sponsor: 
  collaborator: 
  collaborator: 
  collaborator: 
  collaborator: 
  has dmc: Yes
  is fda regulated drug: No
  is fda regulated device: No
  The aim of this study was to investigate the feasibility and mechanism of brachial plexus
        block(BPB) preconditioning in preventing upper limb vascular injury in patients undergoing
        interventional surgery for intracranial aneurysms via transradial access(TRA). A multicenter
        prospective clinical trial was designed. The study subjects were patients undergoing cerebral
        aneurysm embolization with TRA. BPB was given in the experimental group patients and no BPB
        in the control group. To evaluate the short and long-term protective effects of brachial
        plexus block on the upper limb blood vessels injury after operation, the upper limb vasospasm
        and hemodynamic changes during operation, upper limb vascular thrombosis and radial artery
        occlusion after operation were observed in the two groups.
  The aim of this study was to investigate the feasibility and mechanism of BPB preconditioning
        in preventing upper limb vascular injury in patients undergoing interventional surgery for
        intracranial aneurysms viaTRA. A multicenter prospective clinical trial was designed, and the
        study subjects were patients undergoing cerebral aneurysm embolization with TRA. The
        experimental group was givenBPB, and the control group was not given BPB.Firstly, the minimum
        effective concentration (MEC50 and MEC95) of BPB for preventing radial artery spasm was
        determined by sequential method. Then the experimental group patients was treated with
        MEC95.The hemodynamic changes and spasm of the upper limb vessels during the operation, and
        the complications such as thrombosis of the upper limb vessels and radial artery occlusion
        after the operation were compared between the two groups, to evaluate the short-term and
        long-term protective effects of BPB on upper limb vascular injury in those patients.The
        content of IL-2,IL-4,IL-6,IL-10,IL-17,IL-12p70,IFN-γ,TNF-α in plasma was determined by flow
        immunofluorescence before and after operation, to compare the changes of inflammatory
        cytokines between the two groups.
  allocation: Randomized
  intervention model: Parallel Assignment
  intervention model description: This is a multicenter prospective randomized controlled study.Patients were assigned to the two groups with the use of central randomization and competitive enrollment. The experimental group was given brachial plexus block 30 minutes before surgery, and the control group was given routine treatment.
  primary purpose: Prevention
  masking: Triple (Participant, Investigator, Outcomes Assessor)
  masking description: In this study, participants, data recorders(investigators), and outcome assessor were unaware of group assignments
  measure: Assess the degree of vasospasm in the upper extremity artery by angiography
  time frame: During the operation
  description: The degree of vasospasm in the upper extremity artery was assessed by angiography during surgery.
  measure: Assessed thrombosis in the upper extremity artery by ultrasound
  time frame: Day 1 after surgery
  description: Upper extremity artery thrombosis was assessed by ultrasonography after surgery
  measure: Assessed stenosis in the upper extremity artery by ultrasound
  time frame: Day 1 after surgery
  description: Upper extremity artery stenosis was assessed by ultrasonography after surgery
  measure: Assessed occlusion in the upper extremity artery by ultrasound
  time frame: Day 1 after surgery
  description: Upper extremity artery occlusion was assessed by ultrasonography after surgery
  measure: Assess occlusion in the upper extremity artery by angiography or ultrasonography
  time frame: Month 1 after surgery
  description: Upper extremity artery occlusion was assessed by angiography or ultrasonography after surgery
  measure: Evaluate the hemodynamic changes of upper limb artery by ultrasound
  time frame: Before the operation
  description: The hemodynamic changes of upper limb artery were evaluated by ultrasound after BPB , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent(%).
  measure: Evaluate the hemodynamic changes of upper limb vessels by ultrasound
  time frame: Day 1 after surgery
  description: The hemodynamic changes of upper limb vessels were evaluated by ultrasound after BPB. , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent (%).
  measure: Recorded the changes of inflammatory cytokine IL-6 in plasma before and after operation.
  time frame: Day 1 after surgery
  description: The changes of inflammatory cytokine IL-6 in plasma were recorded beforeand after operation by Flow immunofluorescence assay.
  measure: Recorded the changes of inflammatory cytokine IL-10 in plasma before and after operation.
  time frame: Day 1 after surgery
  description: The changes of inflammatory cytokine IL-10 in plasma were recorded beforeand after operation by Flow immunofluorescence assay.
  measure: Evaluated the incidence of postoperative cerebral infarction by magnetic resonance imagingoperation(MRI)
  time frame: Day 1 after surgery
  description: The incidence of postoperative cerebral infarction was evaluated by MRI，Including lacunar cerebral infarction.
  measure: Evaluate the hemodynamic changes of upper limb vessels by ultrasound
  time frame: Month 1 after the surgery
  description: The hemodynamic changes of upper limb vessels were evaluated by ultrasound after BPB. , such as the decrease of vessel cross-sectional area (area),Blood flow (Q), peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (TAMAX ), pulsatility index (PI), resistance index (RI), etc. The change of these parameters will be combined to report in percent (%).
  measure: Calculate MEC50 and MEC95 of ropivacaine in brachial plexus block by sequential method
  time frame: During the operation
  description: The minimum effective concentration（MEC50 and MEC95） of ropivacaine for brachial plexus block to prevent radial artery spasm during operation was determined by sequential method.
  measure: Record VAS score by questionnaire after the surgery
  time frame: Day 0 after the surgery
  description: VAS score was record by questionnaire.The VAS was scored from 0 to 10, with 0 indicating no pain and 10 indicating severe and unbearable pain. The pain scores of patients were recorded after awakening.
  measure: Record VAS score by questionnaire 24h after the surgery
  time frame: Day 1 after the surgery
  description: VAS score was record by questionnaire.The VAS was scored from 0 to 10, with 0 indicating no pain and 10 indicating severe and unbearable pain. The pain scores of patients were recorded 1 day after operation
  measure: Record physician satisfaction by questionnaire
  time frame: Day 0 after the surgery
  description: Physician satisfaction was scored on a scale of 1-5, with a score of 1 indicating very poor and dissatisfied experience and a score of 5 indicating very satisfied. The surgeons were asked to fill in the satisfaction questionnaire according to the operation situation after operation and recorded.
  measure: Record complications of brachial plexus block
  time frame: Day 1 after the surgery
  description: The complications of brachial plexus block such as hematoma, infection, nerve injury were recorded after the surgery.
  arm group label: Brachial plexus block group（Group T）
  arm group type: Experimental
  description: All patients received brachial plexus block 30min before surgery
  arm group label: Control group （Group C）
  arm group type: No Intervention
  description: All patients were not pretreated with brachial plexus block before operation
  intervention type: Drug
  intervention name: Ropivacaine
  description: The MEC50 and MEC95 of ropivacaine for brachial plexus block was measured by sequential method, and then the patients in the experimental group were treated with MEC95.
  arm group label: Brachial plexus block group（Group T）
  other name: brachial plexus block
  criteria: 
  gender: All
  minimum age: 18 Years
  maximum age: 75 Years
  healthy volunteers: No
  last name: Jingjin Li, MD
  role: Principal Investigator
  affiliation: The First Affiliated Hospital with Nanjing Medical University
  last name: Feng Feng, Master
  phone: 13814073686
  email: 316637881@qq.com
  last name: Nan Li, Master
  phone: 15850647102
  email: mzlinan2010@163.com
  facility: 
  status: Recruiting
  contact: 
  contact backup: 
  investigator: 
  country: China
  responsible party type: Sponsor
  mesh term: Intracranial Aneurysm
  mesh term: Aneurysm
  mesh term: Ropivacaine
  sharing ipd: Yes
  ipd description: If anyone is interested in this study, please contact us, and I think we would like to share IPD with him
  ipd info type: Study Protocol
  ipd info type: Clinical Study Report (CSR)
  ipd time frame: Month 1
  ipd access criteria: If anyone is interested in this study, please contact us, and I think we would like to share IPD with him