xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT05965804</url>
    </required_header>
    <id_info>
      <org_study_id>PT-VMM-001</org_study_id>
      <nct_id>NCT05965804</nct_id>
    </id_info>
    <brief_title>Vastus Medialis Activation During McMurray's Test</brief_title>
    <official_title>Muscle Activation Patterns During the McMurray's Test for Knee Examination</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>Ahram Canadian University</agency>
        <agency_class>Other</agency_class>
      </lead_sponsor>
    </sponsors>
    <source>Ahram Canadian University</source>
    <oversight_info>
      <is_fda_regulated_drug>No</is_fda_regulated_drug>
      <is_fda_regulated_device>No</is_fda_regulated_device>
    </oversight_info>
    <brief_summary>
      <textblock>
        This study will use electromyography to evaluate activation patterns of the vastus medialis&#xD;
        and vastus lateralis muscles during the McMurray's knee examination test in different knee&#xD;
        positions.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        The McMurray test is commonly used to assess knee pathology. However, it is unclear which&#xD;
        knee position during this test best isolates activity of the vastus medialis muscle. This&#xD;
        study will measure vastus medialis and lateralis activation using surface electromyography in&#xD;
        30 healthy participants performing the McMurray test. Different knee flexion and rotation&#xD;
        angles will be evaluated to determine which position optimally activates the vastus medialis.&#xD;
        Results may enhance utilization of the McMurray test in rehabilitation programs targeting&#xD;
        this muscle.&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Recruiting</overall_status>
    <start_date type="Anticipated">July 25, 2023</start_date>
    <completion_date type="Anticipated">December 1, 2023</completion_date>
    <primary_completion_date type="Anticipated">November 25, 2023</primary_completion_date>
    <study_type>Observational</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <observational_model>Other</observational_model>
      <time_perspective>Cross-Sectional</time_perspective>
    </study_design_info>
    <primary_outcome>
      <measure>Vastus Medialis Activation</measure>
      <time_frame>Baseline</time_frame>
      <description>Mean EMG activity of the vastus medialis during McMurray test at different knee positions. Measured in microvolts (μV).</description>
    </primary_outcome>
    <secondary_outcome>
      <measure>Vastus lateralis EMG activity during McMurray test (μV)</measure>
      <time_frame>baseline</time_frame>
      <description>Mean EMG activity of the vastus lateralis muscle during the McMurray knee examination test at different knee flexion and rotation angles. Measured in microvolts (μV).</description>
    </secondary_outcome>
    <secondary_outcome>
      <measure>Force exerted during McMurray test measured by dynamometer (Newtons)</measure>
      <time_frame>baseline</time_frame>
      <description>Maximum voluntary isometric knee extension force measured using a handheld dynamometer during the McMurray knee examination test at different knee positions. Measured in Newtons (N).</description>
    </secondary_outcome>
    <number_of_groups>1</number_of_groups>
    <enrollment type="Anticipated">30</enrollment>
    <condition>Electromyography</condition>
    <condition>Knee Injuries</condition>
    <condition>Knee Pain Chronic</condition>
    <arm_group>
      <arm_group_label>Healthy Adults</arm_group_label>
      <description>30 healthy adult participants aged 18-45 years performing the McMurray knee examination test</description>
    </arm_group>
    <intervention>
      <intervention_type>Diagnostic Test</intervention_type>
      <intervention_name>McMurray knee examination test</intervention_name>
      <description>The McMurray test will be performed in different knee flexion and rotation angles.</description>
      <arm_group_label>Healthy Adults</arm_group_label>
    </intervention>
    <eligibility>
      <study_pop>
        <textblock>
          Healthy men and women aged 18-45 recruited from the local community.&#xD;
        </textblock>
      </study_pop>
      <sampling_method>Probability Sample</sampling_method>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
            -  Healthy adults aged 18-45 years&#xD;
  &#xD;
            -  No history of knee pathology&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
            -  Contraindications to EMG&#xD;
  &#xD;
            -  Neurological or muscular disorders&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>18 Years</minimum_age>
      <maximum_age>45 Years</maximum_age>
      <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
    </eligibility>
    <overall_official>
      <last_name>Amal Fawzy, Ph.d</last_name>
      <role>Study Chair</role>
      <affiliation>Faculty of Physical Therapy, Ahram Canadian University</affiliation>
    </overall_official>
    <overall_contact>
      <last_name>Mohamed M ElMeligie</last_name>
      <phone>+201064442032</phone>
      <email>mohamed.elmeligie@acu.edu.eg</email>
    </overall_contact>
    <location>
      <facility>
        <name>Outpatient clinic of faculty of physical therapy, Ahram Canadian University</name>
        <address>
          <city>Al Ḩayy Ath Thāmin</city>
          <state>Giza</state>
          <zip>3221405</zip>
          <country>Egypt</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Mohamed M ElMeligie, Ph.d</last_name>
        <phone>01064442032</phone>
        <email>mohamed.elmeligie@acu.edu.eg</email>
      </contact>
    </location>
    <location_countries>
      <country>Egypt</country>
    </location_countries>
    <verification_date>July 2023</verification_date>
    <study_first_submitted>July 20, 2023</study_first_submitted>
    <study_first_submitted_qc>July 20, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">July 28, 2023</study_first_posted>
    <last_update_submitted>July 20, 2023</last_update_submitted>
    <last_update_submitted_qc>July 20, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">July 28, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Principal Investigator</responsible_party_type>
      <investigator_affiliation>Ahram Canadian University</investigator_affiliation>
      <investigator_full_name>Mohamed Magdy ElMeligie</investigator_full_name>
      <investigator_title>Lecturer of Physical Therapy and Director of Electromyography Lab</investigator_title>
    </responsible_party>
    <condition_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Knee Injuries</mesh_term>
    </condition_browse>
    <patient_data>
      <sharing_ipd>No</sharing_ipd>
    </patient_data>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT05965804
  org study id: PT-VMM-001
  nct id: NCT05965804
  lead sponsor: 
  is fda regulated drug: No
  is fda regulated device: No
  This study will use electromyography to evaluate activation patterns of the vastus medialis
        and vastus lateralis muscles during the McMurray's knee examination test in different knee
        positions.
  The McMurray test is commonly used to assess knee pathology. However, it is unclear which
        knee position during this test best isolates activity of the vastus medialis muscle. This
        study will measure vastus medialis and lateralis activation using surface electromyography in
        30 healthy participants performing the McMurray test. Different knee flexion and rotation
        angles will be evaluated to determine which position optimally activates the vastus medialis.
        Results may enhance utilization of the McMurray test in rehabilitation programs targeting
        this muscle.
  observational model: Other
  time perspective: Cross-Sectional
  measure: Vastus Medialis Activation
  time frame: Baseline
  description: Mean EMG activity of the vastus medialis during McMurray test at different knee positions. Measured in microvolts (μV).
  measure: Vastus lateralis EMG activity during McMurray test (μV)
  time frame: baseline
  description: Mean EMG activity of the vastus lateralis muscle during the McMurray knee examination test at different knee flexion and rotation angles. Measured in microvolts (μV).
  measure: Force exerted during McMurray test measured by dynamometer (Newtons)
  time frame: baseline
  description: Maximum voluntary isometric knee extension force measured using a handheld dynamometer during the McMurray knee examination test at different knee positions. Measured in Newtons (N).
  arm group label: Healthy Adults
  description: 30 healthy adult participants aged 18-45 years performing the McMurray knee examination test
  intervention type: Diagnostic Test
  intervention name: McMurray knee examination test
  description: The McMurray test will be performed in different knee flexion and rotation angles.
  arm group label: Healthy Adults
  study pop: 
  sampling method: Probability Sample
  criteria: 
  gender: All
  minimum age: 18 Years
  maximum age: 45 Years
  healthy volunteers: Accepts Healthy Volunteers
  last name: Amal Fawzy, Ph.d
  role: Study Chair
  affiliation: Faculty of Physical Therapy, Ahram Canadian University
  last name: Mohamed M ElMeligie
  phone: +201064442032
  email: mohamed.elmeligie@acu.edu.eg
  facility: 
  status: Recruiting
  contact: 
  country: Egypt
  responsible party type: Principal Investigator
  investigator affiliation: Ahram Canadian University
  investigator full name: Mohamed Magdy ElMeligie
  investigator title: Lecturer of Physical Therapy and Director of Electromyography Lab
  mesh term: Knee Injuries
  sharing ipd: No