xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT06002880</url>
    </required_header>
    <id_info>
      <org_study_id>Kerr 04-2022</org_study_id>
      <nct_id>NCT06002880</nct_id>
    </id_info>
    <brief_title>Clinical Evaluation of OBU When Used for Indirect Dental Restorations</brief_title>
    <official_title>Clinical Evaluation of OBU When Used for Indirect Dental Restorations</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>Kerr Corporation</agency>
        <agency_class>Industry</agency_class>
      </lead_sponsor>
    </sponsors>
    <source>Kerr Corporation</source>
    <oversight_info>
      <is_fda_regulated_drug>No</is_fda_regulated_drug>
      <is_fda_regulated_device>Yes</is_fda_regulated_device>
      <is_us_export>Yes</is_us_export>
    </oversight_info>
    <brief_summary>
      <textblock>
        The objective of this study is to evaluate the clinical safety and performance of Optibond&#xD;
        Universal (OBU), a single component universal dental adhesive intended for indirect dental&#xD;
        restorations according to manufacturer's Instruction For Use.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        The device used in the study, Optibond Universal (OBU) is a single component universal dental&#xD;
        adhesive intended for direct and indirect dental restorations. OBU is formulated to provide&#xD;
        reliable bond strength with any etch technique, on all common substrates and in combination&#xD;
        with any resin cement without auxiliary products (silane or metal primers) even in absence of&#xD;
        light. OBU is intended for general population use by a dental professional.&#xD;
  &#xD;
        OBU contains an acidic component to etch the tooth surface in order to allow the adhesive to&#xD;
        mechanically adhere to the prepared tooth surface. The adhesive can be used with light or&#xD;
        without light cured prior to application of the restorative material. This allows for the&#xD;
        adhesive to mechanically and chemically bond to the applied restorative material. OBU is&#xD;
        formulated to provide a reliable bond strength, and it's compatible with all etching modes&#xD;
        (self-etch, selective etch, and total etch).&#xD;
  &#xD;
        Aim/Hypothesis/Objective The primary objective of this study is to evaluate the clinical&#xD;
        performance of OBU used in the intended clinical conditions.&#xD;
  &#xD;
        The device will undergo evaluation in the following categories:&#xD;
  &#xD;
        Functional Properties Endodontic posts Ceramic restorations Composite and metal crowns&#xD;
        Pretreatment for indirect restorations Core build-ups&#xD;
  &#xD;
        Endpoints:&#xD;
  &#xD;
        Primary endpoints:&#xD;
  &#xD;
        Evaluation of clinical safety and performance of OBU, a single component universal dental&#xD;
        adhesive intended for indirect dental restorations according to manufacturer's Instruction&#xD;
        For Use.&#xD;
  &#xD;
        (Indirect metal restoration is defined as any restoration made of precious or non-precious&#xD;
        alloy such as inlays, onlays, porcelain fused to metal, metal full coverage crown, metal full&#xD;
        coverage fixed partial denture). All implant restorations are excluded.&#xD;
  &#xD;
        Secondary endpoints:&#xD;
  &#xD;
        Post-operative sensitivity, retention, general periodontal health, and general optical&#xD;
        properties after baseline, 6 months, 1 year and 2 years post-placement.&#xD;
  &#xD;
        The hypothesis to be tested is that OBU is safe and effective in clinical settings when the&#xD;
        device is used according to manufacturer's instructions:&#xD;
  &#xD;
        H0: P ̂_T-P ̂_C≥ ∆ HA: P ̂_T-P ̂_C&lt; ∆ Where ∆ (delta) refers to the non-inferiority margin&#xD;
        set at 10%.&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Recruiting</overall_status>
    <start_date type="Actual">July 14, 2023</start_date>
    <completion_date type="Anticipated">December 30, 2025</completion_date>
    <primary_completion_date type="Anticipated">November 30, 2025</primary_completion_date>
    <phase>N/A</phase>
    <study_type>Interventional</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <allocation>Randomized</allocation>
      <intervention_model>Parallel Assignment</intervention_model>
      <primary_purpose>Treatment</primary_purpose>
      <masking>None (Open Label)</masking>
    </study_design_info>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>Screening</time_frame>
      <description>Preoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>Preparation, Provisional Restoration (up to 6 weeks from Screening)</time_frame>
      <description>Preoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>48 hours after Cementation (up to 4 weeks from Preparation)</time_frame>
      <description>Postoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>Baseline Followup Assessments (approximately 3 weeks from Cementation)</time_frame>
      <description>Postoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>6-months Followup Assessments (approximately 6 months from Baseline)</time_frame>
      <description>Postoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>1-year Followup Assessments (approximately 1 year from Baseline)</time_frame>
      <description>Postoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)</measure>
      <time_frame>2-Year Followup Assessments (approximately 2 years from Baseline)</time_frame>
      <description>Postoperative sensitivity</description>
    </primary_outcome>
    <primary_outcome>
      <measure>FDI (World Dental Federation) Clinical Evaluation Criteria-Modified</measure>
      <time_frame>Baseline Followup Assessments</time_frame>
      <description>Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)</description>
    </primary_outcome>
    <primary_outcome>
      <measure>FDI (World Dental Federation) Clinical Evaluation Criteria-Modified</measure>
      <time_frame>6-months Followup Assessments</time_frame>
      <description>Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)</description>
    </primary_outcome>
    <primary_outcome>
      <measure>FDI (World Dental Federation) Clinical Evaluation Criteria-Modified</measure>
      <time_frame>1-year Followup Assessments</time_frame>
      <description>Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)</description>
    </primary_outcome>
    <primary_outcome>
      <measure>FDI (World Dental Federation) Clinical Evaluation Criteria-Modified</measure>
      <time_frame>2-Year Followup Assessments</time_frame>
      <description>Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)</description>
    </primary_outcome>
    <number_of_arms>8</number_of_arms>
    <enrollment type="Anticipated">160</enrollment>
    <condition>Sensitivity, Tooth</condition>
    <arm_group>
      <arm_group_label>Post/Core-Total Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Endodontic posts and/or cores-Total etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Ceramic-Total Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Glass-ceramics-Total etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Metal/Zi-Total Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Metal-Zi-Total etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Composite-Total Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Composite-Total etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Post/Core-Self Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Endodontic posts and/or cores-Self etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Ceramic-Self Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Glass-ceramics-Self etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Metal/Zi-Self Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Metal-Zi-Self etch</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Composite-Self Etch</arm_group_label>
      <arm_group_type>Experimental</arm_group_type>
      <description>Composite-Self etch</description>
    </arm_group>
    <intervention>
      <intervention_type>Device</intervention_type>
      <intervention_name>Optibond Universal</intervention_name>
      <description>OBU™ will be used used for the cementation of indirect restorations (ceramic restorations, composite, zirconia and metal crowns) and pretreatment for indirect restoration, according to manufacturer's Instruction For Use in self-etch and total-etch modes.</description>
      <arm_group_label>Ceramic-Self Etch</arm_group_label>
      <arm_group_label>Ceramic-Total Etch</arm_group_label>
      <arm_group_label>Composite-Self Etch</arm_group_label>
      <arm_group_label>Composite-Total Etch</arm_group_label>
      <arm_group_label>Metal/Zi-Self Etch</arm_group_label>
      <arm_group_label>Metal/Zi-Total Etch</arm_group_label>
      <arm_group_label>Post/Core-Self Etch</arm_group_label>
      <arm_group_label>Post/Core-Total Etch</arm_group_label>
    </intervention>
    <eligibility>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
            -  Is willing to provide voluntary written informed consent in English.&#xD;
  &#xD;
            -  Is in good medical health and able to tolerate the dental procedures.&#xD;
  &#xD;
            -  Has 1 qualifying either vital or endodontically treated molar and/or premolar that&#xD;
               requires an endodontic post and or core build-ups with subsequent indirect restoration&#xD;
               or an indirect restoration only. Only 1 tooth per quadrant can be included in the&#xD;
               study if more than 1 tooth in need of restoration. The maximum number of restorations&#xD;
               will not exceed two per patient.&#xD;
  &#xD;
            -  The tooth must be restorable, i.e. without subgingival caries and must have a minimum&#xD;
               of 2-3 mm healthy supragingival tooth structure.&#xD;
  &#xD;
            -  Study teeth must have an antagonist in the opposite jaw and have a neighboring tooth&#xD;
               on at least one side.&#xD;
  &#xD;
            -  Study teeth must be vital and without any symptoms suggesting irreversible damage of&#xD;
               the pulp, or endodontically treated and hermetically filled according to standards of&#xD;
               care (i.e., free of clinical signs and symptoms of periapical pathology).&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
            -  Is currently taking part in an evaluation of other dental procedures.&#xD;
  &#xD;
            -  Has chronic periodontitis or rampant caries.&#xD;
  &#xD;
            -  The study tooth exhibits clinical signs of periapical pathology.&#xD;
  &#xD;
            -  The study tooth has a history of self-reported preoperative pulpal problems.&#xD;
  &#xD;
            -  The study tooth that has been restored using eugenol containing materials.&#xD;
  &#xD;
            -  Study Subjects with severe parafunctional habits or occlusal issues affecting the&#xD;
               subject teeth.&#xD;
  &#xD;
            -  Women who are pregnant (self-reported). It is standard of care to postpone routine&#xD;
               dental procedures and radiographed until after pregnancy.&#xD;
  &#xD;
            -  Women who are breast feeding.&#xD;
  &#xD;
            -  Known allergy to methacrylates or other components of resin composites, local&#xD;
               anesthetics, or metals used for dental restorations.&#xD;
  &#xD;
            -  An employee of the sponsor or members of their immediate family.&#xD;
  &#xD;
            -  Condition affecting salivary flow (e.g., salivary gland disorder, Sjögren's Syndrome,&#xD;
               xerogenic medications).&#xD;
  &#xD;
            -  Are unwilling or unable to have dental radiographs or photographs taken of their&#xD;
               dentition and soft tissues.&#xD;
  &#xD;
            -  Unable to return to the recall visits.&#xD;
  &#xD;
            -  Any other condition which is the view of the investigator may affect the ability of a&#xD;
               patient to complete the study.&#xD;
  &#xD;
            -  Teeth with implant restorations.&#xD;
  &#xD;
            -  Third molars.&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>18 Years</minimum_age>
      <maximum_age>100 Years</maximum_age>
      <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
    </eligibility>
    <overall_official>
      <last_name>Sibel Antonson</last_name>
      <role>Principal Investigator</role>
      <affiliation>NSU CDM</affiliation>
    </overall_official>
    <overall_contact>
      <last_name>Sibel Antonson</last_name>
      <phone>9542627604</phone>
      <email>sibel.antonson@nova.edu</email>
    </overall_contact>
    <overall_contact_backup>
      <last_name>Ria Achong-Bowe</last_name>
      <phone>(954) 262-7393</phone>
      <email>rachongb@nova.edu</email>
    </overall_contact_backup>
    <location>
      <facility>
        <name>Nova Southeastern University, College of dental Medicine</name>
        <address>
          <city>Fort Lauderdale</city>
          <state>Florida</state>
          <zip>33328</zip>
          <country>United States</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Sibel Antonson</last_name>
        <phone>954-262-7604</phone>
        <email>sibel.antonson@nova.edu</email>
      </contact>
      <contact_backup>
        <last_name>Ria Achong-Bowe</last_name>
        <phone>(954) 262-7393</phone>
        <email>rachongb@nova.edu</email>
      </contact_backup>
    </location>
    <location_countries>
      <country>United States</country>
    </location_countries>
    <reference>
      <citation>Hill EE. Dental cements for definitive luting: a review and practical clinical considerations. Dent Clin North Am. 2007 Jul;51(3):643-58, vi. doi: 10.1016/j.cden.2007.04.002.</citation>
      <PMID>17586148</PMID>
    </reference>
    <reference>
      <citation>Alharbi A, Rocca GT, Dietschi D, Krejci I. Semidirect composite onlay with cavity sealing: a review of clinical procedures. J Esthet Restor Dent. 2014 Mar-Apr;26(2):97-106. doi: 10.1111/jerd.12067. Epub 2013 Dec 17.</citation>
      <PMID>24341472</PMID>
    </reference>
    <reference>
      <citation>Hickel R, Peschke A, Tyas M, Mjor I, Bayne S, Peters M, Hiller KA, Randall R, Vanherle G, Heintze SD. FDI World Dental Federation: clinical criteria for the evaluation of direct and indirect restorations-update and clinical examples. Clin Oral Investig. 2010 Aug;14(4):349-66. doi: 10.1007/s00784-010-0432-8. Epub 2010 Jul 14.</citation>
      <PMID>20628774</PMID>
    </reference>
    <verification_date>August 2023</verification_date>
    <study_first_submitted>July 24, 2023</study_first_submitted>
    <study_first_submitted_qc>August 18, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">August 21, 2023</study_first_posted>
    <last_update_submitted>August 18, 2023</last_update_submitted>
    <last_update_submitted_qc>August 18, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">August 21, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Principal Investigator</responsible_party_type>
      <investigator_affiliation>Nova Southeastern University</investigator_affiliation>
      <investigator_full_name>Sibel Antonson</investigator_full_name>
      <investigator_title>Professor and Assistant Dean for Research and Development</investigator_title>
    </responsible_party>
    <condition_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Dentin Sensitivity</mesh_term>
    </condition_browse>
    <patient_data>
      <sharing_ipd>No</sharing_ipd>
    </patient_data>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT06002880
  org study id: Kerr 04-2022
  nct id: NCT06002880
  lead sponsor: 
  is fda regulated drug: No
  is fda regulated device: Yes
  is us export: Yes
  The objective of this study is to evaluate the clinical safety and performance of Optibond
        Universal (OBU), a single component universal dental adhesive intended for indirect dental
        restorations according to manufacturer's Instruction For Use.
  The device used in the study, Optibond Universal (OBU) is a single component universal dental
        adhesive intended for direct and indirect dental restorations. OBU is formulated to provide
        reliable bond strength with any etch technique, on all common substrates and in combination
        with any resin cement without auxiliary products (silane or metal primers) even in absence of
        light. OBU is intended for general population use by a dental professional.
  
        OBU contains an acidic component to etch the tooth surface in order to allow the adhesive to
        mechanically adhere to the prepared tooth surface. The adhesive can be used with light or
        without light cured prior to application of the restorative material. This allows for the
        adhesive to mechanically and chemically bond to the applied restorative material. OBU is
        formulated to provide a reliable bond strength, and it's compatible with all etching modes
        (self-etch, selective etch, and total etch).
  
        Aim/Hypothesis/Objective The primary objective of this study is to evaluate the clinical
        performance of OBU used in the intended clinical conditions.
  
        The device will undergo evaluation in the following categories:
  
        Functional Properties Endodontic posts Ceramic restorations Composite and metal crowns
        Pretreatment for indirect restorations Core build-ups
  
        Endpoints:
  
        Primary endpoints:
  
        Evaluation of clinical safety and performance of OBU, a single component universal dental
        adhesive intended for indirect dental restorations according to manufacturer's Instruction
        For Use.
  
        (Indirect metal restoration is defined as any restoration made of precious or non-precious
        alloy such as inlays, onlays, porcelain fused to metal, metal full coverage crown, metal full
        coverage fixed partial denture). All implant restorations are excluded.
  
        Secondary endpoints:
  
        Post-operative sensitivity, retention, general periodontal health, and general optical
        properties after baseline, 6 months, 1 year and 2 years post-placement.
  
        The hypothesis to be tested is that OBU is safe and effective in clinical settings when the
        device is used according to manufacturer's instructions:
  
        H0: P ̂_T-P ̂_C≥ ∆ HA: P ̂_T-P ̂_C< ∆ Where ∆ (delta) refers to the non-inferiority margin
        set at 10%.
  allocation: Randomized
  intervention model: Parallel Assignment
  primary purpose: Treatment
  masking: None (Open Label)
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: Screening
  description: Preoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: Preparation, Provisional Restoration (up to 6 weeks from Screening)
  description: Preoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: 48 hours after Cementation (up to 4 weeks from Preparation)
  description: Postoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: Baseline Followup Assessments (approximately 3 weeks from Cementation)
  description: Postoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: 6-months Followup Assessments (approximately 6 months from Baseline)
  description: Postoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: 1-year Followup Assessments (approximately 1 year from Baseline)
  description: Postoperative sensitivity
  measure: Sensitivity Questionnaire-Visual Analog Scale 1 to 5 (1=No pain, 5=Worst pain possible)
  time frame: 2-Year Followup Assessments (approximately 2 years from Baseline)
  description: Postoperative sensitivity
  measure: FDI (World Dental Federation) Clinical Evaluation Criteria-Modified
  time frame: Baseline Followup Assessments
  description: Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)
  measure: FDI (World Dental Federation) Clinical Evaluation Criteria-Modified
  time frame: 6-months Followup Assessments
  description: Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)
  measure: FDI (World Dental Federation) Clinical Evaluation Criteria-Modified
  time frame: 1-year Followup Assessments
  description: Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)
  measure: FDI (World Dental Federation) Clinical Evaluation Criteria-Modified
  time frame: 2-Year Followup Assessments
  description: Esthetic Qualities, Functional Properties, Biological Properties (1 clinically excellent-5 clinically poor Scale)
  arm group label: Post/Core-Total Etch
  arm group type: Experimental
  description: Endodontic posts and/or cores-Total etch
  arm group label: Ceramic-Total Etch
  arm group type: Experimental
  description: Glass-ceramics-Total etch
  arm group label: Metal/Zi-Total Etch
  arm group type: Experimental
  description: Metal-Zi-Total etch
  arm group label: Composite-Total Etch
  arm group type: Experimental
  description: Composite-Total etch
  arm group label: Post/Core-Self Etch
  arm group type: Experimental
  description: Endodontic posts and/or cores-Self etch
  arm group label: Ceramic-Self Etch
  arm group type: Experimental
  description: Glass-ceramics-Self etch
  arm group label: Metal/Zi-Self Etch
  arm group type: Experimental
  description: Metal-Zi-Self etch
  arm group label: Composite-Self Etch
  arm group type: Experimental
  description: Composite-Self etch
  intervention type: Device
  intervention name: Optibond Universal
  description: OBU™ will be used used for the cementation of indirect restorations (ceramic restorations, composite, zirconia and metal crowns) and pretreatment for indirect restoration, according to manufacturer's Instruction For Use in self-etch and total-etch modes.
  arm group label: Ceramic-Self Etch
  arm group label: Ceramic-Total Etch
  arm group label: Composite-Self Etch
  arm group label: Composite-Total Etch
  arm group label: Metal/Zi-Self Etch
  arm group label: Metal/Zi-Total Etch
  arm group label: Post/Core-Self Etch
  arm group label: Post/Core-Total Etch
  criteria: 
  gender: All
  minimum age: 18 Years
  maximum age: 100 Years
  healthy volunteers: Accepts Healthy Volunteers
  last name: Sibel Antonson
  role: Principal Investigator
  affiliation: NSU CDM
  last name: Sibel Antonson
  phone: 9542627604
  email: sibel.antonson@nova.edu
  last name: Ria Achong-Bowe
  phone: (954) 262-7393
  email: rachongb@nova.edu
  facility: 
  status: Recruiting
  contact: 
  contact backup: 
  country: United States
  citation: Hill EE. Dental cements for definitive luting: a review and practical clinical considerations. Dent Clin North Am. 2007 Jul;51(3):643-58, vi. doi: 10.1016/j.cden.2007.04.002.
  PMID: 17586148
  citation: Alharbi A, Rocca GT, Dietschi D, Krejci I. Semidirect composite onlay with cavity sealing: a review of clinical procedures. J Esthet Restor Dent. 2014 Mar-Apr;26(2):97-106. doi: 10.1111/jerd.12067. Epub 2013 Dec 17.
  PMID: 24341472
  citation: Hickel R, Peschke A, Tyas M, Mjor I, Bayne S, Peters M, Hiller KA, Randall R, Vanherle G, Heintze SD. FDI World Dental Federation: clinical criteria for the evaluation of direct and indirect restorations-update and clinical examples. Clin Oral Investig. 2010 Aug;14(4):349-66. doi: 10.1007/s00784-010-0432-8. Epub 2010 Jul 14.
  PMID: 20628774
  responsible party type: Principal Investigator
  investigator affiliation: Nova Southeastern University
  investigator full name: Sibel Antonson
  investigator title: Professor and Assistant Dean for Research and Development
  mesh term: Dentin Sensitivity
  sharing ipd: No