xml: <clinical_study>
    <!-- This xml conforms to an XML Schema at:
      https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
    <required_header>
      <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
      <link_text>Link to the current ClinicalTrials.gov record.</link_text>
      <url>https://clinicaltrials.gov/ct2/show/NCT06025825</url>
    </required_header>
    <id_info>
      <org_study_id>26379996/10</org_study_id>
      <nct_id>NCT06025825</nct_id>
    </id_info>
    <brief_title>Comparative Effect of Palatal Injection in Pediatric Patient</brief_title>
    <official_title>Comparative Effect of Palatal Injection on Pain Perception in Pediatric Patient</official_title>
    <sponsors>
      <lead_sponsor>
        <agency>Ankara Yildirim Beyazıt University</agency>
        <agency_class>Other</agency_class>
      </lead_sponsor>
    </sponsors>
    <source>Ankara Yildirim Beyazıt University</source>
    <oversight_info>
      <has_dmc>No</has_dmc>
      <is_fda_regulated_drug>Yes</is_fda_regulated_drug>
      <is_fda_regulated_device>No</is_fda_regulated_device>
      <is_us_export>No</is_us_export>
    </oversight_info>
    <brief_summary>
      <textblock>
        The aim of this study is to compare the pain perception of pediatric patients during&#xD;
        extraction with and without palatal injection and to show whether articaine HCl and lidocaine&#xD;
        HCl can provide palatal anesthesia in maxillary tooth extraction without the need for a&#xD;
        second palatal injection. In addition, to evaluate the superiority of articaine HCl and&#xD;
        lidocaine HCl to each other in providing local anesthesia and to compare pain control between&#xD;
        each other. An observational prospective clinical study is planned to be performed in&#xD;
        children aged 8-12 years with maxillary tooth extraction indication. It is planned to include&#xD;
        96 children in the study. Patients will be divided into 6 groups. After the application of&#xD;
        anesthesia and after tooth extraction, the pain they feel with visual analogue scale and the&#xD;
        level of pain observed with the Wong-Baker faces pain rating scale will be marked.&#xD;
      </textblock>
    </brief_summary>
    <detailed_description>
      <textblock>
        The study is planned to be carried out in children aged 8-12 years with maxillary tooth&#xD;
        extraction indication. It is planned to include 96 children in the study. According to&#xD;
        studies, under the assumption that a difference of 5 units in the number of patients would be&#xD;
        considered significant, it was planned to include at least 5 patients in each group at 95&#xD;
        power and α=0.05 significance level. However, the number of patients has been updated to 96&#xD;
        by increasing the effect size for more meaningful results.&#xD;
  &#xD;
        6 different groups will be formed in patients.&#xD;
  &#xD;
          1. st group: Buccal infiltration anesthesia + palatal infiltration anesthesia (with&#xD;
             articaine HCl)&#xD;
  &#xD;
          2. nd group: Buccal infiltration anesthesia + palatal infiltration anesthesia (with&#xD;
             lidocaine HCl)&#xD;
  &#xD;
          3. rd group: Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)&#xD;
  &#xD;
          4. th group: Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)&#xD;
  &#xD;
          5. th group: Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)&#xD;
  &#xD;
          6. th group: Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)&#xD;
             Behavioral guidance will be given to all patients who have an indication for tooth&#xD;
             extraction for various reasons and will be included in the study with the tell-show-do&#xD;
             technique before treatment, after clinical and radiographic examinations. Topical&#xD;
             anesthesia will be applied with Ultracare 20% benzocaine gel (Ultradent Products Inc.,&#xD;
             USA) for 1 minute to the mucobuccal fold area closest to the tooth to be extracted. The&#xD;
             same application will be applied to the palatal region for the groups that will undergo&#xD;
             palatal anesthesia. Then, for group 1, group 3 and group 5, a local anesthetic&#xD;
             containing 1:100,000 adrenaline and articaine HCL 4%; For Group 2, Group 4 and Group 6,&#xD;
             local anesthetic containing 20 mg/ml+0.0125 mg/ml adrenaline and lidocaine HCL was&#xD;
             injected through a 30 gauge dental needle. 0.5 in Group 1 and Group 2. cc will be used&#xD;
             for buccal anesthesia, 0.2 cc anesthesia will be used for palatal anaesthesia. For other&#xD;
             groups, 1 cc of anesthesia will be administered from the buccal. After the application&#xD;
             of local anesthesia, tooth extraction will be performed. All anesthesia applications and&#xD;
             tooth extractions will be performed by the same pediatric dentist (E.C.T). Patients will&#xD;
             be asked to evaluate their pain after dental anesthesia and tooth extraction separately&#xD;
             with VAS. It will also be evaluated by the Physician performing the procedure with the&#xD;
             Wong-Baker evaluation scale.&#xD;
  &#xD;
        Among the different pain assessment methods reported in the literature, rating scales to&#xD;
        measure their intensity are mostly used in clinical studies as they represent themselves. The&#xD;
        VAS is one of the most commonly used self-reported measures of pain; It measures a property&#xD;
        that is believed to change over a continuum of values that are not easy to measure directly.&#xD;
        However, it is a one-dimensional scale that measures only the sensory component or intensity&#xD;
        of the pain experience. The millimeter scale is the most commonly used measuring range and&#xD;
        produces a possible score range of 0 to 100 with a 10 cm line.&#xD;
  &#xD;
        The dentist who performed the tooth extraction marked the line representing the level of pain&#xD;
        intensity perceived by the patients. The Wong-Baker faces pain rating scale (WBFPS) presents&#xD;
        6 faces with increasing pain rating from left to right. Each face was assigned a scale from 0&#xD;
        to 10 indicated on the scale... Face 0 does not hurt at all, Face 2 hurts a little, Face 4&#xD;
        hurts a little more, Face 6 hurts more, Face 8 hurts a lot, and Face 10 hurts as much as you&#xD;
        can imagine' it denotes.&#xD;
      </textblock>
    </detailed_description>
    <overall_status>Recruiting</overall_status>
    <start_date type="Actual">May 2, 2023</start_date>
    <completion_date type="Anticipated">September 5, 2023</completion_date>
    <primary_completion_date type="Actual">August 28, 2023</primary_completion_date>
    <study_type>Observational [Patient Registry]</study_type>
    <has_expanded_access>No</has_expanded_access>
    <study_design_info>
      <observational_model>Cohort</observational_model>
      <time_perspective>Prospective</time_perspective>
    </study_design_info>
    <target_duration>1 Day</target_duration>
    <primary_outcome>
      <measure>Evaluation of pain during tooth extraction after anesthesia with VAS</measure>
      <time_frame>baseline and maximum 8 minutes</time_frame>
      <description>The VAS is one of the most commonly used self-reported measures of pain; It measures a property that is believed to change over a continuum of values that are not easy to measure directly. However, it is a one-dimensional scale that measures only the sensory component or intensity of the pain experience. The millimeter scale is the most commonly used measuring range and produces a possible score range of 0 to 100 with a 10 cm line</description>
    </primary_outcome>
    <primary_outcome>
      <measure>Evaluation of pain during tooth extraction after anesthesia with Wong-Baker</measure>
      <time_frame>baseline and maximum 8 minutes</time_frame>
      <description>The Wong-Baker faces pain rating scale (WBFPS) presents 6 faces with increasing pain rating from left to right. Each face was assigned a score from 0 to 10, indicated on the scale. it means that Face 0 doesn't hurt at all, Face 2 hurts a little, Face 4 hurts a little more, Face 6 hurts more, Face 8 hurts a lot, and Face 10 hurts as much as you can imagine</description>
    </primary_outcome>
    <number_of_groups>6</number_of_groups>
    <enrollment type="Anticipated">96</enrollment>
    <condition>Local Anesthetic Complication</condition>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl)</arm_group_label>
      <description>Before extraction, buccal and palatal infiltration anesthesia with articaine will perform. Following anesthesia, extraction will carry out.</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl)</arm_group_label>
      <description>Before extraction, buccal and palatal infiltration anesthesia with lidocaine will perform. Following anesthesia, extraction will carry out.</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)</arm_group_label>
      <description>Before extraction, buccal infiltration anesthesia with articaine will perform. After 5 minutes, extraction will carry out.</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)</arm_group_label>
      <description>Before extraction, buccal infiltration anesthesia with lidocaine will perform. After 5 minutes, extraction will carry out.</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)</arm_group_label>
      <description>Before extraction, buccal infiltration anesthesia with articaine will perform. After 8 minutes, extraction will carry out.</description>
    </arm_group>
    <arm_group>
      <arm_group_label>Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)</arm_group_label>
      <description>Before extraction, buccal infiltration anesthesia with lidocaine will perform. After 8 minutes, extraction will carry out.</description>
    </arm_group>
    <intervention>
      <intervention_type>Drug</intervention_type>
      <intervention_name>Articaine Hydrochloride + Epinephrine</intervention_name>
      <description>Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl) was applied for first group Buccal infiltration anesthesia was applied and 5 minutes was waited before extraction.&#xD;
  Buccal infiltration anesthesia was applied and 8 minutes was waited before extraction.</description>
      <arm_group_label>Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)</arm_group_label>
      <arm_group_label>Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)</arm_group_label>
      <arm_group_label>Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl)</arm_group_label>
      <other_name>ultracaine ds</other_name>
    </intervention>
    <intervention>
      <intervention_type>Drug</intervention_type>
      <intervention_name>Lidocaine Hydrochloride + Epinephrine</intervention_name>
      <description>Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl) was applied for second group Buccal infiltration anesthesia was applied and 5 minutes was waited before extraction for fourth group Buccal infiltration anesthesia was applied and 8 minutes was waited before extraction for sixth group</description>
      <arm_group_label>Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)</arm_group_label>
      <arm_group_label>Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)</arm_group_label>
      <arm_group_label>Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl)</arm_group_label>
      <other_name>jetocaine</other_name>
    </intervention>
    <eligibility>
      <study_pop>
        <textblock>
          The study is planned to be carried out in children aged 8-12 years with maxillary tooth&#xD;
          extraction indication.&#xD;
        </textblock>
      </study_pop>
      <sampling_method>Probability Sample</sampling_method>
      <criteria>
        <textblock>
          Inclusion Criteria:&#xD;
  &#xD;
            -  The child has no systemic disease&#xD;
  &#xD;
            -  Absence of acute toothache&#xD;
  &#xD;
            -  Child's first tooth extraction treatment&#xD;
  &#xD;
            -  No suspected allergy to benzocaine, lidocaine or articaine&#xD;
  &#xD;
            -  Comply with Frankl's 3 or Frankl's 4 behavioral assessments&#xD;
  &#xD;
          Exclusion Criteria:&#xD;
  &#xD;
            -  Patients who do not want to participate in the study&#xD;
  &#xD;
            -  Any systemic condition&#xD;
  &#xD;
            -  Patients with any drug or local anesthetic allergy&#xD;
  &#xD;
            -  Patient has acute toothache or abscess&#xD;
  &#xD;
            -  Patients with previous tooth extraction experience&#xD;
  &#xD;
            -  Frankl 1 and Frankl 2 patients&#xD;
        </textblock>
      </criteria>
      <gender>All</gender>
      <minimum_age>8 Years</minimum_age>
      <maximum_age>12 Years</maximum_age>
    </eligibility>
    <overall_official>
      <last_name>ceren tatlı, assist.Prof</last_name>
      <role>Principal Investigator</role>
      <affiliation>Ankara Yildirim Beyazıt University</affiliation>
    </overall_official>
    <overall_contact>
      <last_name>Kevser sancak</last_name>
      <phone>+905556446580</phone>
      <email>kevsersancak89@gmail.com</email>
    </overall_contact>
    <overall_contact_backup>
      <last_name>Ceren Tatlı</last_name>
    </overall_contact_backup>
    <location>
      <facility>
        <name>Ankara Yıldırım beyazıt University, Faculty of Dentistry</name>
        <address>
          <city>Ankara</city>
          <zip>06790</zip>
          <country>Turkey</country>
        </address>
      </facility>
      <status>Recruiting</status>
      <contact>
        <last_name>Kevser SANCAK, DDS</last_name>
        <phone>+905556446580</phone>
        <email>kevsersancak89@gmail.com</email>
      </contact>
    </location>
    <location_countries>
      <country>Turkey</country>
    </location_countries>
    <reference>
      <citation>Bataineh AB, Nusair YM, Al-Rahahleh RQ. Comparative study of articaine and lidocaine without palatal injection for maxillary teeth extraction. Clin Oral Investig. 2019 Aug;23(8):3239-3248. doi: 10.1007/s00784-018-2738-x. Epub 2018 Nov 12.</citation>
      <PMID>30417227</PMID>
    </reference>
    <reference>
      <citation>Raslan N, Masri R. A randomized clinical trial to compare pain levels during three types of oral anesthetic injections and the effect of Dentalvibe(R) on injection pain in children. Int J Paediatr Dent. 2018 Jan;28(1):102-110. doi: 10.1111/ipd.12313. Epub 2017 Jun 24.</citation>
      <PMID>28646527</PMID>
    </reference>
    <results_reference>
      <citation>Uckan S, Dayangac E, Araz K. Is permanent maxillary tooth removal without palatal injection possible? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):733-5. doi: 10.1016/j.tripleo.2005.12.005. Epub 2006 Mar 20. Erratum In: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Apr;103(4):580.</citation>
      <PMID>17138173</PMID>
    </results_reference>
    <verification_date>August 2023</verification_date>
    <study_first_submitted>August 30, 2023</study_first_submitted>
    <study_first_submitted_qc>August 30, 2023</study_first_submitted_qc>
    <study_first_posted type="Actual">September 6, 2023</study_first_posted>
    <last_update_submitted>August 30, 2023</last_update_submitted>
    <last_update_submitted_qc>August 30, 2023</last_update_submitted_qc>
    <last_update_posted type="Actual">September 6, 2023</last_update_posted>
    <responsible_party>
      <responsible_party_type>Principal Investigator</responsible_party_type>
      <investigator_affiliation>Ankara Yildirim Beyazıt University</investigator_affiliation>
      <investigator_full_name>Kevser SANCAK</investigator_full_name>
      <investigator_title>asistant professor</investigator_title>
    </responsible_party>
    <keyword>local anesthesia</keyword>
    <keyword>pain</keyword>
    <intervention_browse>
      <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
      <mesh_term>Lidocaine</mesh_term>
      <mesh_term>Epinephrine</mesh_term>
      <mesh_term>Racepinephrine</mesh_term>
      <mesh_term>Carticaine</mesh_term>
      <mesh_term>Epinephryl borate</mesh_term>
    </intervention_browse>
    <patient_data>
      <sharing_ipd>Undecided</sharing_ipd>
    </patient_data>
    <!-- Results have not yet been posted for this study                                          -->
  </clinical_study>
  
  
text: download date: ClinicalTrials.gov processed this data on September 20, 2023
  link text: Link to the current ClinicalTrials.gov record.
  url: https://clinicaltrials.gov/ct2/show/NCT06025825
  org study id: 26379996/10
  nct id: NCT06025825
  lead sponsor: 
  has dmc: No
  is fda regulated drug: Yes
  is fda regulated device: No
  is us export: No
  The aim of this study is to compare the pain perception of pediatric patients during
        extraction with and without palatal injection and to show whether articaine HCl and lidocaine
        HCl can provide palatal anesthesia in maxillary tooth extraction without the need for a
        second palatal injection. In addition, to evaluate the superiority of articaine HCl and
        lidocaine HCl to each other in providing local anesthesia and to compare pain control between
        each other. An observational prospective clinical study is planned to be performed in
        children aged 8-12 years with maxillary tooth extraction indication. It is planned to include
        96 children in the study. Patients will be divided into 6 groups. After the application of
        anesthesia and after tooth extraction, the pain they feel with visual analogue scale and the
        level of pain observed with the Wong-Baker faces pain rating scale will be marked.
  The study is planned to be carried out in children aged 8-12 years with maxillary tooth
        extraction indication. It is planned to include 96 children in the study. According to
        studies, under the assumption that a difference of 5 units in the number of patients would be
        considered significant, it was planned to include at least 5 patients in each group at 95
        power and α=0.05 significance level. However, the number of patients has been updated to 96
        by increasing the effect size for more meaningful results.
  
        6 different groups will be formed in patients.
  
          1. st group: Buccal infiltration anesthesia + palatal infiltration anesthesia (with
             articaine HCl)
  
          2. nd group: Buccal infiltration anesthesia + palatal infiltration anesthesia (with
             lidocaine HCl)
  
          3. rd group: Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)
  
          4. th group: Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)
  
          5. th group: Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)
  
          6. th group: Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)
             Behavioral guidance will be given to all patients who have an indication for tooth
             extraction for various reasons and will be included in the study with the tell-show-do
             technique before treatment, after clinical and radiographic examinations. Topical
             anesthesia will be applied with Ultracare 20% benzocaine gel (Ultradent Products Inc.,
             USA) for 1 minute to the mucobuccal fold area closest to the tooth to be extracted. The
             same application will be applied to the palatal region for the groups that will undergo
             palatal anesthesia. Then, for group 1, group 3 and group 5, a local anesthetic
             containing 1:100,000 adrenaline and articaine HCL 4%; For Group 2, Group 4 and Group 6,
             local anesthetic containing 20 mg/ml+0.0125 mg/ml adrenaline and lidocaine HCL was
             injected through a 30 gauge dental needle. 0.5 in Group 1 and Group 2. cc will be used
             for buccal anesthesia, 0.2 cc anesthesia will be used for palatal anaesthesia. For other
             groups, 1 cc of anesthesia will be administered from the buccal. After the application
             of local anesthesia, tooth extraction will be performed. All anesthesia applications and
             tooth extractions will be performed by the same pediatric dentist (E.C.T). Patients will
             be asked to evaluate their pain after dental anesthesia and tooth extraction separately
             with VAS. It will also be evaluated by the Physician performing the procedure with the
             Wong-Baker evaluation scale.
  
        Among the different pain assessment methods reported in the literature, rating scales to
        measure their intensity are mostly used in clinical studies as they represent themselves. The
        VAS is one of the most commonly used self-reported measures of pain; It measures a property
        that is believed to change over a continuum of values that are not easy to measure directly.
        However, it is a one-dimensional scale that measures only the sensory component or intensity
        of the pain experience. The millimeter scale is the most commonly used measuring range and
        produces a possible score range of 0 to 100 with a 10 cm line.
  
        The dentist who performed the tooth extraction marked the line representing the level of pain
        intensity perceived by the patients. The Wong-Baker faces pain rating scale (WBFPS) presents
        6 faces with increasing pain rating from left to right. Each face was assigned a scale from 0
        to 10 indicated on the scale... Face 0 does not hurt at all, Face 2 hurts a little, Face 4
        hurts a little more, Face 6 hurts more, Face 8 hurts a lot, and Face 10 hurts as much as you
        can imagine' it denotes.
  observational model: Cohort
  time perspective: Prospective
  measure: Evaluation of pain during tooth extraction after anesthesia with VAS
  time frame: baseline and maximum 8 minutes
  description: The VAS is one of the most commonly used self-reported measures of pain; It measures a property that is believed to change over a continuum of values that are not easy to measure directly. However, it is a one-dimensional scale that measures only the sensory component or intensity of the pain experience. The millimeter scale is the most commonly used measuring range and produces a possible score range of 0 to 100 with a 10 cm line
  measure: Evaluation of pain during tooth extraction after anesthesia with Wong-Baker
  time frame: baseline and maximum 8 minutes
  description: The Wong-Baker faces pain rating scale (WBFPS) presents 6 faces with increasing pain rating from left to right. Each face was assigned a score from 0 to 10, indicated on the scale. it means that Face 0 doesn't hurt at all, Face 2 hurts a little, Face 4 hurts a little more, Face 6 hurts more, Face 8 hurts a lot, and Face 10 hurts as much as you can imagine
  arm group label: Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl)
  description: Before extraction, buccal and palatal infiltration anesthesia with articaine will perform. Following anesthesia, extraction will carry out.
  arm group label: Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl)
  description: Before extraction, buccal and palatal infiltration anesthesia with lidocaine will perform. Following anesthesia, extraction will carry out.
  arm group label: Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)
  description: Before extraction, buccal infiltration anesthesia with articaine will perform. After 5 minutes, extraction will carry out.
  arm group label: Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)
  description: Before extraction, buccal infiltration anesthesia with lidocaine will perform. After 5 minutes, extraction will carry out.
  arm group label: Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)
  description: Before extraction, buccal infiltration anesthesia with articaine will perform. After 8 minutes, extraction will carry out.
  arm group label: Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)
  description: Before extraction, buccal infiltration anesthesia with lidocaine will perform. After 8 minutes, extraction will carry out.
  intervention type: Drug
  intervention name: Articaine Hydrochloride + Epinephrine
  description: Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl) was applied for first group Buccal infiltration anesthesia was applied and 5 minutes was waited before extraction.
  Buccal infiltration anesthesia was applied and 8 minutes was waited before extraction.
  arm group label: Buccal infiltration anesthesia (5 minutes waiting time with articaine HCl)
  arm group label: Buccal infiltration anesthesia (8 minutes waiting time with articaine HCl)
  arm group label: Buccal infiltration anesthesia + palatal infiltration anesthesia (with articaine HCl)
  other name: ultracaine ds
  intervention type: Drug
  intervention name: Lidocaine Hydrochloride + Epinephrine
  description: Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl) was applied for second group Buccal infiltration anesthesia was applied and 5 minutes was waited before extraction for fourth group Buccal infiltration anesthesia was applied and 8 minutes was waited before extraction for sixth group
  arm group label: Buccal infiltration anesthesia (5 minutes waiting time with lidocaine HCl)
  arm group label: Buccal infiltration anesthesia (8 minutes waiting time with lidocaine HCl)
  arm group label: Buccal infiltration anesthesia + palatal infiltration anesthesia (with lidocaine HCl)
  other name: jetocaine
  study pop: 
  sampling method: Probability Sample
  criteria: 
  gender: All
  minimum age: 8 Years
  maximum age: 12 Years
  last name: ceren tatlı, assist.Prof
  role: Principal Investigator
  affiliation: Ankara Yildirim Beyazıt University
  last name: Kevser sancak
  phone: +905556446580
  email: kevsersancak89@gmail.com
  last name: Ceren Tatlı
  facility: 
  status: Recruiting
  contact: 
  country: Turkey
  citation: Bataineh AB, Nusair YM, Al-Rahahleh RQ. Comparative study of articaine and lidocaine without palatal injection for maxillary teeth extraction. Clin Oral Investig. 2019 Aug;23(8):3239-3248. doi: 10.1007/s00784-018-2738-x. Epub 2018 Nov 12.
  PMID: 30417227
  citation: Raslan N, Masri R. A randomized clinical trial to compare pain levels during three types of oral anesthetic injections and the effect of Dentalvibe(R) on injection pain in children. Int J Paediatr Dent. 2018 Jan;28(1):102-110. doi: 10.1111/ipd.12313. Epub 2017 Jun 24.
  PMID: 28646527
  citation: Uckan S, Dayangac E, Araz K. Is permanent maxillary tooth removal without palatal injection possible? Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):733-5. doi: 10.1016/j.tripleo.2005.12.005. Epub 2006 Mar 20. Erratum In: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Apr;103(4):580.
  PMID: 17138173
  responsible party type: Principal Investigator
  investigator affiliation: Ankara Yildirim Beyazıt University
  investigator full name: Kevser SANCAK
  investigator title: asistant professor
  mesh term: Lidocaine
  mesh term: Epinephrine
  mesh term: Racepinephrine
  mesh term: Carticaine
  mesh term: Epinephryl borate
  sharing ipd: Undecided