<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT04438161</url>
  </required_header>
  <id_info>
    <org_study_id>202007199</org_study_id>
    <secondary_id>1P50HD096719</secondary_id>
    <nct_id>NCT04438161</nct_id>
  </id_info>
  <brief_title>Study to Understand Risk and Resilience Opportunity for Newborns After Delivery</brief_title>
  <acronym>SURROuND</acronym>
  <official_title>Identification of Newborns at High Risk for the Occurrence of Preventable Child Maltreatment: Phase 3 of Project 3 in the Overall Center for Innovation in Child Maltreatment Policy, Research, and Training (CICM), a Capstone Centers Grant.</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Washington University School of Medicine</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
    <collaborator>
      <agency>Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)</agency>
      <agency_class>NIH</agency_class>
    </collaborator>
  </sponsors>
  <source>Washington University School of Medicine</source>
  <oversight_info>
    <has_dmc>Yes</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      Childhood Maltreatment (CM) has highly deleterious effects on human development and is a&#xD;
      preventable known cause of enduring psychopathology in the United States. Infants and young&#xD;
      children are at particularly high risk for physical harm from abuse and neglect, comprising&#xD;
      over 60% of all child maltreatment fatalities. An increasing number of studies point to the&#xD;
      ability to target prevention of CM by estimating individual specific risk at the time of&#xD;
      birth, on the basis of readily-accessible data elements of birth records. This clinical trial&#xD;
      is a randomized controlled trial embedded within a prospective longitudinal study, in which&#xD;
      families of infants recruited prenatally or in the newborn period are randomized to an&#xD;
      enhanced level of engagement in resource navigation, which we refer to as Personalized&#xD;
      Education Regarding Clinical and Community Supports (PERCCS). The enhancement involves keying&#xD;
      recommendations for evidence-informed interventions for the prevention of CM to established&#xD;
      risk factors for ascertained within a family.&#xD;
&#xD;
      The parent longitudinal cohort study involves enrollment of a diverse population of families&#xD;
      of newborns (prenatally or in the immediate postnatal period) for the purpose of ascertaining&#xD;
      sociodemographic, psychological (eg. parental stress) and family psychiatric risk factors for&#xD;
      (a) child maltreatment (b) unmet service needs, and (c) adverse behavioral outcomes of the&#xD;
      children. Families are contacted quarterly to track acquisition of support services that are&#xD;
      relevant to the prevention of child maltreatment. At age 18 months early childhood behavioral&#xD;
      outcomes are ascertained, biomaterials collected, and official-report child maltreatment&#xD;
      records from the State of Missouri are individually cross-matched with identifiers of the&#xD;
      children and their parents.&#xD;
&#xD;
      Two major outcomes are examined:&#xD;
&#xD;
      The first is whether the engagement protocol results in a higher level of acquisition and&#xD;
      active participation in recommended preventive intervention services by the families&#xD;
      (including home visitation, parental mental health care, evidence-based parenting education,&#xD;
      and others delineated in Table 1, see below).&#xD;
&#xD;
      The second is the rate of child maltreatment (CM) ascertained in official Missouri state&#xD;
      administrative records for which individual informed consent to individually-cross reference&#xD;
      is obtained by the families in the course of their enrollment in the parent longitudinal&#xD;
      study.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Sample: The sample will be recruited from the Washington University School of Medicine&#xD;
      Obstetrical Service within the Barnes Jewish Christian (BJC) Health System, on which there&#xD;
      are over 3000 Missouri childbirths per year, serving an urban population of families that are&#xD;
      disproportionately affected by poverty. Fifty-five per cent of patients report a family&#xD;
      income less than $20,000, 65% of the mothers are unemployed, and the majority of the newborns&#xD;
      are on Medicaid or are Medicaid-eligible. In preliminary screening efforts, over one third of&#xD;
      the mothers reported their own childhood histories of maltreatment, and approximately one&#xD;
      half score in the clinical range for depressive symptomatology.&#xD;
&#xD;
      Methods: A schematic summarizing study enrollment, participant randomization, and&#xD;
      ascertainment of outcomes is provided in Figure 1.&#xD;
&#xD;
      Study Approach and Design: N=400 families are in the process of being enrolled in the parent&#xD;
      longitudinal study. Among those who fall in an elevated risk category (upper 50% of the&#xD;
      sample for total count of established risk factors) we will randomize 150 families 2:1 to&#xD;
      Personalized Education Regarding Clinical and Community Supports (PERCCS) versus Usual Care.&#xD;
      Risk counts are calculated by the total number of established predictors of risk for CM&#xD;
      (itemized in Table 1) ascertained from birth records and: i) a screen for maternal&#xD;
      depression, ii) a screen for maternal childhood trauma, and iii) a screen for active intimate&#xD;
      partner violence. Utilization of community-based evidence-informed support services will be&#xD;
      ascertained at baseline and quarterly thereafter for all study participants. Official-report&#xD;
      Child Maltreatment data from Missouri state administrative data will be individually linked&#xD;
      with participant research records when the children reach 18 months of age.&#xD;
&#xD;
      PERCCS involves i) a review with the mother of all family CM risks ascertained in the context&#xD;
      of their own individual screening ii) recommendations of community and clinical interventions&#xD;
      which substantively respond to those risks and are available to the subject (on the basis of&#xD;
      each individual subject's zip code, insurance, and eligibility for the interventions),&#xD;
      collectively the personalized family resource plan, iii) facilitation of contact between the&#xD;
      subject and the respective provider agencies to initiate enrollment; and iv) authorization&#xD;
      for the research team to share the personalized risk profile and support recommendations with&#xD;
      the infant's outpatient primary care provider.&#xD;
&#xD;
      The community and clinical supports responsive to specific risk factors are listed in Table&#xD;
      1, which summarizes the array of evidence-informed preventions that will be presented to the&#xD;
      families, and the correspondence with each to specific CM risks ascertained within a family.&#xD;
      Table 2 depicts the set of scripts which are used by the study team to standardize all&#xD;
      aspects of the review of endorsed risks, their potential adverse effects on parenting, and&#xD;
      the opportunities for mitigation through evidence-informed intervention.&#xD;
&#xD;
      All participants will receive care as usual, including the provision of a summary document&#xD;
      itemizing key community supports for families of infants, a continuously-updated local&#xD;
      community resource handbook, a published parenting guide, and opportunity to enroll&#xD;
      free-of-charge in a virtual parenting education and developmental surveillance program,&#xD;
      babynavigator.com.&#xD;
&#xD;
      Key Measures:&#xD;
&#xD;
      The Utilization of Community Services (UCS) is a survey that will be used to ascertain&#xD;
      engagement of families in community supports and interventions, including tracking of both&#xD;
      frequency and duration. This survey is completed at the time of study enrollment to establish&#xD;
      a baseline, and quarterly thereafter until the completion of the study when a child reaches&#xD;
      18 months of age.&#xD;
&#xD;
      State Records: The second primary outcome, rate of child maltreatment, will rely on official&#xD;
      state records from the State of Missouri Department of Social Services. Participants are&#xD;
      aware that accessing service records or CM report data are retrospective when acquired and do&#xD;
      not pose any risk or liability to them nor can it impact services received.&#xD;
&#xD;
      Statistical Analyses:&#xD;
&#xD;
      I. Intent-to-treat analysis of impact of PERCCS on service utilization. We will calculate the&#xD;
      total proportion of evidence-informed services indicated by risk profiles of all families&#xD;
      within each group (the intervention group and the control group) and compare the groups using&#xD;
      chi square analysis.&#xD;
&#xD;
      II. Intent-to-treat analysis of the impact of PERCCS on the occurrence of child maltreatment.&#xD;
      We will compare the rate of official-report abuse/neglect between the groups using chi square&#xD;
      analysis.&#xD;
&#xD;
      III. (Secondary) We will conduct logistic regression analysis simultaneously examining the&#xD;
      effects of risk count and service access on official report child maltreatment outcome.&#xD;
&#xD;
      The randomized controlled trial has adequate statistical power to detect an odds ratio of 2.0&#xD;
      for the effect of PERRCS in reducing child maltreatment outcome.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Terminated</overall_status>
  <why_stopped>
    Enrollment delayed due to COVID-19 and converting to virtual work. The study recruited&#xD;
    sufficient participants for planned data analysis. Any newly enrolled participants would not&#xD;
    have enough time to return for first follow up. Parent study continues&#xD;
  </why_stopped>
  <start_date type="Actual">January 26, 2021</start_date>
  <completion_date type="Actual">December 20, 2022</completion_date>
  <primary_completion_date type="Actual">December 20, 2022</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Prevention</primary_purpose>
    <masking>Single (Participant)</masking>
    <masking_description>Single (study personnel blind to intervention allocation status)</masking_description>
  </study_design_info>
  <primary_outcome>
    <measure>Service Utilization</measure>
    <time_frame>Not more than 18 months postpartum</time_frame>
    <description>Proportion of evidence-informed services indicated by risk profiles of all families within group acquired over the course of follow-up.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Child Maltreatment</measure>
    <time_frame>Not more than 18 months postpartum</time_frame>
    <description>Rate of official reports of child maltreatment, ascertained from records of the Missouri Department of Social Services at age 18 months. Child Maltreatment (number of cases of child abuse and neglect) as measured by official state administrative records</description>
  </primary_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Actual">105</enrollment>
  <condition>A. Longitudinal Cohort n=400</condition>
  <condition>B. Lower Risk (n=45) and Higher Risk (n=105) Randomized 2:1 to PERCCS Intervention</condition>
  <arm_group>
    <arm_group_label>Low Risk</arm_group_label>
    <arm_group_type>Active Comparator</arm_group_type>
    <description>Low risk natural history study (n=250*)&#xD;
*Participants will be randomized 2:1 PERCCS:Control, and the randomization will be within successive sets of three families who fall in either &quot;high risk&quot; counts (n=105) families for child maltreatment or &quot;low risk&quot; counts (n=45) families.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>High Risk</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>High risk families in prospective longitudinal study of newborns (n=150*).&#xD;
*Participants will be randomized 2:1 PERCCS:Control, and the randomization will be within successive sets of three families who fall in either &quot;high risk&quot; counts (n=105) families for child maltreatment or &quot;low risk&quot; counts (n=45) families.&#xD;
Participants in this arm will be randomized to:&#xD;
PERCCS (see attached figure and table for details)&#xD;
Care as Usual</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>PERCCS: Personalized Education Regarding Clinical and Community Supports</intervention_name>
    <description>A brief follow-up to the screening provided to 50% of the consented families (randomly assigned) that links their specific familial risks to community interventions.</description>
    <arm_group_label>High Risk</arm_group_label>
    <arm_group_label>Low Risk</arm_group_label>
    <other_name>Clinical and Community Supports</other_name>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Participants will be Missouri residents&#xD;
&#xD;
          -  18 years of age or older&#xD;
&#xD;
          -  Engaged in the BJC Healthcare Obstetrics or Newborn Services&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Participants who are not Missouri residents&#xD;
&#xD;
          -  Under the age of 18 years&#xD;
&#xD;
          -  Not engaged in the BJC Healthcare Obstetrics or Newborn Services.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>99 Years</maximum_age>
    <healthy_volunteers>Accepts Healthy Volunteers</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Mini Tandon, DO</last_name>
    <role>Principal Investigator</role>
    <affiliation>Faculty</affiliation>
  </overall_official>
  <location>
    <facility>
      <name>Washington University</name>
      <address>
        <city>Saint Louis</city>
        <state>Missouri</state>
        <zip>63108</zip>
        <country>United States</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>United States</country>
  </location_countries>
  <reference>
    <citation>Constantino JN. Child Maltreatment Prevention and the Scope of Child and Adolescent Psychiatry. Child Adolesc Psychiatr Clin N Am. 2016 Apr;25(2):157-65. doi: 10.1016/j.chc.2015.11.003. Epub 2016 Jan 11.</citation>
    <PMID>26980121</PMID>
  </reference>
  <reference>
    <citation>Jaffee SR. Child Maltreatment and Risk for Psychopathology in Childhood and Adulthood. Annu Rev Clin Psychol. 2017 May 8;13:525-551. doi: 10.1146/annurev-clinpsy-032816-045005. Epub 2017 Mar 30.</citation>
    <PMID>28375720</PMID>
  </reference>
  <reference>
    <citation>US DHHS, Children's Bureau (2017). Child Maltreatment 2015. Washington, DC: Author.U.S.</citation>
  </reference>
  <reference>
    <citation>Wu SS, Ma CX, Carter RL, Ariet M, Feaver EA, Resnick MB, Roth J. Risk factors for infant maltreatment: a population-based study. Child Abuse Negl. 2004 Dec;28(12):1253-64. doi: 10.1016/j.chiabu.2004.07.005.</citation>
    <PMID>15607768</PMID>
  </reference>
  <reference>
    <citation>Putnam-Hornstein, E., &amp; Needell, B. (2011). Predictors of child protective service contact between birth and age five: An examination of California's 2002 birth cohort. Children and Youth Services Review, 33(8), 1337-1344.</citation>
  </reference>
  <reference>
    <citation>Gilbert R, Widom CS, Browne K, Fergusson D, Webb E, Janson S. Burden and consequences of child maltreatment in high-income countries. Lancet. 2009 Jan 3;373(9657):68-81. doi: 10.1016/S0140-6736(08)61706-7. Epub 2008 Dec 4.</citation>
    <PMID>19056114</PMID>
  </reference>
  <reference>
    <citation>Paulsell, D., Avellar, S., Sama Martin, E., &amp; Del Grosso, P. Home Visiting Evidence of Effectiveness Review: Executive Summary. Office of Planning, Research and Evaluation, Administration for Children and Families, U.S. Department of Health and Human Services. 2011. Washington, DC.</citation>
  </reference>
  <reference>
    <citation>Jonson-Reid M, Kohl PL, Drake B. Child and adult outcomes of chronic child maltreatment. Pediatrics. 2012 May;129(5):839-45. doi: 10.1542/peds.2011-2529. Epub 2012 Apr 23.</citation>
    <PMID>22529281</PMID>
  </reference>
  <verification_date>March 2023</verification_date>
  <study_first_submitted>June 16, 2020</study_first_submitted>
  <study_first_submitted_qc>June 16, 2020</study_first_submitted_qc>
  <study_first_posted type="Actual">June 18, 2020</study_first_posted>
  <last_update_submitted>March 8, 2023</last_update_submitted>
  <last_update_submitted_qc>March 8, 2023</last_update_submitted_qc>
  <last_update_posted type="Actual">March 13, 2023</last_update_posted>
  <responsible_party>
    <responsible_party_type>Principal Investigator</responsible_party_type>
    <investigator_affiliation>Washington University School of Medicine</investigator_affiliation>
    <investigator_full_name>Mini Tandon</investigator_full_name>
    <investigator_title>Associate Professor of Child and Adolescent Psychiatry</investigator_title>
  </responsible_party>
  <keyword>Child maltreatment, preventative intervention, case management, newborn, infancy</keyword>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT04438161
org study id: 202007199
secondary id: 1P50HD096719
nct id: NCT04438161
lead sponsor: 
collaborator: 
has dmc: Yes
is fda regulated drug: No
is fda regulated device: No
Childhood Maltreatment (CM) has highly deleterious effects on human development and is a
      preventable known cause of enduring psychopathology in the United States. Infants and young
      children are at particularly high risk for physical harm from abuse and neglect, comprising
      over 60% of all child maltreatment fatalities. An increasing number of studies point to the
      ability to target prevention of CM by estimating individual specific risk at the time of
      birth, on the basis of readily-accessible data elements of birth records. This clinical trial
      is a randomized controlled trial embedded within a prospective longitudinal study, in which
      families of infants recruited prenatally or in the newborn period are randomized to an
      enhanced level of engagement in resource navigation, which we refer to as Personalized
      Education Regarding Clinical and Community Supports (PERCCS). The enhancement involves keying
      recommendations for evidence-informed interventions for the prevention of CM to established
      risk factors for ascertained within a family.

      The parent longitudinal cohort study involves enrollment of a diverse population of families
      of newborns (prenatally or in the immediate postnatal period) for the purpose of ascertaining
      sociodemographic, psychological (eg. parental stress) and family psychiatric risk factors for
      (a) child maltreatment (b) unmet service needs, and (c) adverse behavioral outcomes of the
      children. Families are contacted quarterly to track acquisition of support services that are
      relevant to the prevention of child maltreatment. At age 18 months early childhood behavioral
      outcomes are ascertained, biomaterials collected, and official-report child maltreatment
      records from the State of Missouri are individually cross-matched with identifiers of the
      children and their parents.

      Two major outcomes are examined:

      The first is whether the engagement protocol results in a higher level of acquisition and
      active participation in recommended preventive intervention services by the families
      (including home visitation, parental mental health care, evidence-based parenting education,
      and others delineated in Table 1, see below).

      The second is the rate of child maltreatment (CM) ascertained in official Missouri state
      administrative records for which individual informed consent to individually-cross reference
      is obtained by the families in the course of their enrollment in the parent longitudinal
      study.
Sample: The sample will be recruited from the Washington University School of Medicine
      Obstetrical Service within the Barnes Jewish Christian (BJC) Health System, on which there
      are over 3000 Missouri childbirths per year, serving an urban population of families that are
      disproportionately affected by poverty. Fifty-five per cent of patients report a family
      income less than $20,000, 65% of the mothers are unemployed, and the majority of the newborns
      are on Medicaid or are Medicaid-eligible. In preliminary screening efforts, over one third of
      the mothers reported their own childhood histories of maltreatment, and approximately one
      half score in the clinical range for depressive symptomatology.

      Methods: A schematic summarizing study enrollment, participant randomization, and
      ascertainment of outcomes is provided in Figure 1.

      Study Approach and Design: N=400 families are in the process of being enrolled in the parent
      longitudinal study. Among those who fall in an elevated risk category (upper 50% of the
      sample for total count of established risk factors) we will randomize 150 families 2:1 to
      Personalized Education Regarding Clinical and Community Supports (PERCCS) versus Usual Care.
      Risk counts are calculated by the total number of established predictors of risk for CM
      (itemized in Table 1) ascertained from birth records and: i) a screen for maternal
      depression, ii) a screen for maternal childhood trauma, and iii) a screen for active intimate
      partner violence. Utilization of community-based evidence-informed support services will be
      ascertained at baseline and quarterly thereafter for all study participants. Official-report
      Child Maltreatment data from Missouri state administrative data will be individually linked
      with participant research records when the children reach 18 months of age.

      PERCCS involves i) a review with the mother of all family CM risks ascertained in the context
      of their own individual screening ii) recommendations of community and clinical interventions
      which substantively respond to those risks and are available to the subject (on the basis of
      each individual subject's zip code, insurance, and eligibility for the interventions),
      collectively the personalized family resource plan, iii) facilitation of contact between the
      subject and the respective provider agencies to initiate enrollment; and iv) authorization
      for the research team to share the personalized risk profile and support recommendations with
      the infant's outpatient primary care provider.

      The community and clinical supports responsive to specific risk factors are listed in Table
      1, which summarizes the array of evidence-informed preventions that will be presented to the
      families, and the correspondence with each to specific CM risks ascertained within a family.
      Table 2 depicts the set of scripts which are used by the study team to standardize all
      aspects of the review of endorsed risks, their potential adverse effects on parenting, and
      the opportunities for mitigation through evidence-informed intervention.

      All participants will receive care as usual, including the provision of a summary document
      itemizing key community supports for families of infants, a continuously-updated local
      community resource handbook, a published parenting guide, and opportunity to enroll
      free-of-charge in a virtual parenting education and developmental surveillance program,
      babynavigator.com.

      Key Measures:

      The Utilization of Community Services (UCS) is a survey that will be used to ascertain
      engagement of families in community supports and interventions, including tracking of both
      frequency and duration. This survey is completed at the time of study enrollment to establish
      a baseline, and quarterly thereafter until the completion of the study when a child reaches
      18 months of age.

      State Records: The second primary outcome, rate of child maltreatment, will rely on official
      state records from the State of Missouri Department of Social Services. Participants are
      aware that accessing service records or CM report data are retrospective when acquired and do
      not pose any risk or liability to them nor can it impact services received.

      Statistical Analyses:

      I. Intent-to-treat analysis of impact of PERCCS on service utilization. We will calculate the
      total proportion of evidence-informed services indicated by risk profiles of all families
      within each group (the intervention group and the control group) and compare the groups using
      chi square analysis.

      II. Intent-to-treat analysis of the impact of PERCCS on the occurrence of child maltreatment.
      We will compare the rate of official-report abuse/neglect between the groups using chi square
      analysis.

      III. (Secondary) We will conduct logistic regression analysis simultaneously examining the
      effects of risk count and service access on official report child maltreatment outcome.

      The randomized controlled trial has adequate statistical power to detect an odds ratio of 2.0
      for the effect of PERRCS in reducing child maltreatment outcome.
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Prevention
masking: Single (Participant)
masking description: Single (study personnel blind to intervention allocation status)
measure: Service Utilization
time frame: Not more than 18 months postpartum
description: Proportion of evidence-informed services indicated by risk profiles of all families within group acquired over the course of follow-up.
measure: Child Maltreatment
time frame: Not more than 18 months postpartum
description: Rate of official reports of child maltreatment, ascertained from records of the Missouri Department of Social Services at age 18 months. Child Maltreatment (number of cases of child abuse and neglect) as measured by official state administrative records
arm group label: Low Risk
arm group type: Active Comparator
description: Low risk natural history study (n=250*)
*Participants will be randomized 2:1 PERCCS:Control, and the randomization will be within successive sets of three families who fall in either "high risk" counts (n=105) families for child maltreatment or "low risk" counts (n=45) families.
arm group label: High Risk
arm group type: Experimental
description: High risk families in prospective longitudinal study of newborns (n=150*).
*Participants will be randomized 2:1 PERCCS:Control, and the randomization will be within successive sets of three families who fall in either "high risk" counts (n=105) families for child maltreatment or "low risk" counts (n=45) families.
Participants in this arm will be randomized to:
PERCCS (see attached figure and table for details)
Care as Usual
intervention type: Behavioral
intervention name: PERCCS: Personalized Education Regarding Clinical and Community Supports
description: A brief follow-up to the screening provided to 50% of the consented families (randomly assigned) that links their specific familial risks to community interventions.
arm group label: High Risk
arm group label: Low Risk
other name: Clinical and Community Supports
criteria: 
gender: All
minimum age: 18 Years
maximum age: 99 Years
healthy volunteers: Accepts Healthy Volunteers
last name: Mini Tandon, DO
role: Principal Investigator
affiliation: Faculty
facility: 
country: United States
citation: Constantino JN. Child Maltreatment Prevention and the Scope of Child and Adolescent Psychiatry. Child Adolesc Psychiatr Clin N Am. 2016 Apr;25(2):157-65. doi: 10.1016/j.chc.2015.11.003. Epub 2016 Jan 11.
PMID: 26980121
citation: Jaffee SR. Child Maltreatment and Risk for Psychopathology in Childhood and Adulthood. Annu Rev Clin Psychol. 2017 May 8;13:525-551. doi: 10.1146/annurev-clinpsy-032816-045005. Epub 2017 Mar 30.
PMID: 28375720
citation: US DHHS, Children's Bureau (2017). Child Maltreatment 2015. Washington, DC: Author.U.S.
citation: Wu SS, Ma CX, Carter RL, Ariet M, Feaver EA, Resnick MB, Roth J. Risk factors for infant maltreatment: a population-based study. Child Abuse Negl. 2004 Dec;28(12):1253-64. doi: 10.1016/j.chiabu.2004.07.005.
PMID: 15607768
citation: Putnam-Hornstein, E., & Needell, B. (2011). Predictors of child protective service contact between birth and age five: An examination of California's 2002 birth cohort. Children and Youth Services Review, 33(8), 1337-1344.
citation: Gilbert R, Widom CS, Browne K, Fergusson D, Webb E, Janson S. Burden and consequences of child maltreatment in high-income countries. Lancet. 2009 Jan 3;373(9657):68-81. doi: 10.1016/S0140-6736(08)61706-7. Epub 2008 Dec 4.
PMID: 19056114
citation: Paulsell, D., Avellar, S., Sama Martin, E., & Del Grosso, P. Home Visiting Evidence of Effectiveness Review: Executive Summary. Office of Planning, Research and Evaluation, Administration for Children and Families, U.S. Department of Health and Human Services. 2011. Washington, DC.
citation: Jonson-Reid M, Kohl PL, Drake B. Child and adult outcomes of chronic child maltreatment. Pediatrics. 2012 May;129(5):839-45. doi: 10.1542/peds.2011-2529. Epub 2012 Apr 23.
PMID: 22529281
responsible party type: Principal Investigator
investigator affiliation: Washington University School of Medicine
investigator full name: Mini Tandon
investigator title: Associate Professor of Child and Adolescent Psychiatry
sharing ipd: No