<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT04428996</url>
  </required_header>
  <id_info>
    <org_study_id>B-BR-108-066</org_study_id>
    <nct_id>NCT04428996</nct_id>
  </id_info>
  <brief_title>Social Cognition and Interaction Training (SCIT) for Taiwanese People With Severe Mental Illness</brief_title>
  <official_title>Social Cognition and Interaction Training (SCIT) for Taiwanese People With Severe Mental Illness</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>National Cheng-Kung University Hospital</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>National Cheng-Kung University Hospital</source>
  <oversight_info>
    <has_dmc>No</has_dmc>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      Social cognition dysfunction (including emotional perception, theory of mind, and attribution&#xD;
      bias) is a common dysfunction in serious mental illness, which may influence their life roles&#xD;
      and daily functions. The social cognition and interaction training (SCIT) is a manual-guide&#xD;
      group intervention that can apply to people with serious mental illness.Thus this study aims&#xD;
      to conduct SCIT groups in Taiwan to investigate its feasibility and effectiveness.&#xD;
&#xD;
      This study will include 30 clients. Investigators will randomly allot participants into two&#xD;
      group, and conduct a crossover design. The experimental group will receive a 60-minutes&#xD;
      manual-guide SCIT session each week for 20 times, which will be leaded by 2 licensed&#xD;
      occupational therapists. After the intervention, investigators will analyze demographic data&#xD;
      and compare the difference between experimental group and control group on the social&#xD;
      cognition performance.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Social cognition dysfunction (including emotional perception, theory of mind, and attribution&#xD;
      bias) is a common dysfunction in serious mental illness, which may influence their life roles&#xD;
      and daily functions. The social cognition and interaction training (SCIT) is a manual-guide&#xD;
      group intervention that can apply to people with serious mental illness. There have been&#xD;
      evidences showing that the SCIT could improve emotional perception, theory of mind,&#xD;
      attribution bias, and social relationship. However, there are no SCIT studies in Taiwan yet.&#xD;
      Thus this study aims to conduct SCIT groups in Taiwan to investigate its feasibility and&#xD;
      effectiveness.&#xD;
&#xD;
      This study will include 30 clients from a day care ward and community rehabilitation center,&#xD;
      excluding clients with acute onset, brain injury, intellectual disability and substance&#xD;
      abuse. The investigators will randomly allot participants into two group, and conduct a&#xD;
      crossover design. Before and after the intervention protocol, both group receive evaluations&#xD;
      of clinical symptoms, emotional perception, theory of mind, and attributional bias. The&#xD;
      experimental group will receive a 60-minutes manual-guide SCIT session each week for 20&#xD;
      times, which will be leaded by 2 licensed occupational therapists. There are three main&#xD;
      themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3)&#xD;
      integration: checking it out. After each theme of the intervention, participants will fill&#xD;
      out a satisfaction survey. And a senior occupational therapist will observe the group and&#xD;
      rate the fidelity of the group. The control group will receive treatment as usual.&#xD;
&#xD;
      After the intervention, the investigators will analyze demographic data and compare the&#xD;
      difference between experimental group and control group on the social cognition performance.&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Not yet recruiting</last_known_status>
  <start_date type="Anticipated">June 2020</start_date>
  <completion_date type="Anticipated">December 2021</completion_date>
  <primary_completion_date type="Anticipated">December 2021</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Crossover Assignment</intervention_model>
    <primary_purpose>Treatment</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Test of Theory of mind #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>Includes language theory of mind and non-verbal theory of mind. Language theory of mind mainly measures the ability of cognitive components and emotional components. There are ten major questions, each of which contains four sub-questions. The first sub-question is a memory question, which must be answered correctly. The scores of the other three sub-questions are calculated. The full score of the language assignment is 30 points. There are ten questions in total, and the full score for non-verbal theory of mind is 20 points. About the internal consistency reliability, the language part is .91 and the non-verbal part is .93. About the test-retest reliability, the language part is .89 and the non-verbal part is .88.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Ambiguous Intentions Hostility Questionnaire #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>This is a measure of the attribution of the subject to the event, including 5 negative situations. Ask the subject to imagine that they are the protagonist in the situation. The first question responds to others' reasons for themselves. The second question is 6 The Likert scale (1 is absolutely not, 6 is absolutely yes) whether responding to others is intentional, the third question is to respond to your own with a 5 point Likert scale (1 is completely not, 5 is very angry) The degree of anger, the fourth question is also the degree of blaming others with a 5-point Likert scale (1 is not at all, 5 is absolutely), and finally asked the subjects to respond to the actions they will take; first Questions and the fifth question are evaluated by the evaluator based on his response. This is a tool with good reliability and validity, including internal consistency (alpha = .84 ~ .86) and inter-tester reliability (ICCs = .91 ~ .99).</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Attributional Style Questionnaire #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>This is a questionnaire to assess the social cognition of the subjects, including the theory of mind, cognitive schema and verbal memory. There are 10 scenarios, each of which contains 3 yes-or-no questions, and one question is about degree of judgment. The scoring method is scoring according to three sub-items. The content of the response of the subjects is compared with the norm. If it is lower than two standard deviations, the degree is disabled.</description>
  </primary_outcome>
  <primary_outcome>
    <measure>Diagnostic Analysis of Nonverbal Accuracy, Taiwanese version #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>The DANVA-2-TW, a parallel version of the Diagnostic Analysis of Non-verbal Accuracy 2 (Nowicki and Duke, 1994), is a validated (Pan et al., 2009; Tseng et al., 2013), culturally suitable (Tseng et al., 2012) nonverbal measure for Han Chinese, considering that race and culture may considerably affect the accuracy of judging nonverbal emotions (Jack et al., 2012; Wickline et al., 2009). The DANVA-2-TW comprises 60 facial photographs and 60 voice clips representing specific emotions and intensities, including happy, sad, angry, fearful, and neutral stimuli.</description>
  </primary_outcome>
  <secondary_outcome>
    <measure>Self-Reported Graphic version of Personal and Social Performance rating scale #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>The PSP scale was developed for assessing patients' function by mental health professions . The rater can assess one global score as well as sub-scores of the four domains: socially useful activities, personal and social relationships, self-care, and disturbing and aggressive behaviors. The PSP showed good interrater (ICC = 0.87) and test-retest (ICCs &gt; 0.90) reliability (Patrick et al., 2009) and adequate validity (Cronbach aloha = 0.76) (Kawata &amp; Revicki, 2008). As many studies showed that people with schizophrenia have greater impairment in processing speed and verbal memory than visual spatial-perception memory, a graphic version of PSP (SRG-PSP) was developed. The results of this SRG-PSP were significantly correlated to those of their corresponding criteria on the PSP. The SRG-PSP total score ranges from 12 to 51, and the higher the score, the better social performance.</description>
  </secondary_outcome>
  <secondary_outcome>
    <measure>Trail Making Test #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>This is a test to assess visual attention, task conversion, processing speed and cognitive flexibility. Contains two parts. Part A is a number from 1-25, and the subjects must connect the numbers in order. Part B contains 12 numbers and 12 letters. The subjects must connect the numbers and the zodiac in sequence (1-Mouse-2-Bull-3 ...). The scoring method is the individual seconds to complete these two tasks. According to the research by Wang et al. In 2018, this tool has good reliability (ICC&gt; .75).</description>
  </secondary_outcome>
  <other_outcome>
    <measure>Brief Psychiatric Rating Scale</measure>
    <time_frame>baseline</time_frame>
    <description>The BPRS (Overall &amp; Gorham, 1962) is one of the most frequently used instruments for evaluating psychopathology in people with schizophrenia. Its psychometric properties in terms of reliability, validity and sensitivity have been extensively examined (Leucht et al., 2005). It measures psychiatric symptoms such as depression, anxiety, hallucinations and unusual behavior. Each symptom is rated 1 (not present) to 7 (extremely severe).</description>
  </other_outcome>
  <other_outcome>
    <measure>Brief Symptom Rating Scale-50 #Change from baseline at 20 weeks and 40 weeks</measure>
    <time_frame>baseline, 20th week, 40th week</time_frame>
    <description>Lee, Lee, Yen, Lin, and Lue (1990) revised the Symptom Checklist-90-R scale (Derogatis, Rickels, &amp; Rock, 1976) to develop BSRS-50. The scale contains 50 symptom descriptions and can be summarized into 10 concepts, including physicalization, compulsiveness, interpersonal sensitivity, depression, anxiety, hostility, fear, suspiciousness, psychosis and additional symptoms. Subjects report the degree of distress they feel based on each symptom. Each item is rated 0-4 points, 0 points: no, 4 points: very powerful. Research supports BRSR-50 with good psychometric characteristics</description>
  </other_outcome>
  <number_of_arms>2</number_of_arms>
  <enrollment type="Anticipated">30</enrollment>
  <condition>Mental Health Disorder</condition>
  <arm_group>
    <arm_group_label>Arm AB</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>&quot;A&quot; means SCIT program, and &quot;B&quot; means treatment as usual. Arm AB will receive a 60-minutes manual-guide SCIT session each week for 20 times first, then receive treatment as usual.&#xD;
Before the SCIT session, after the SCIT session and after 20 weeks treatment as usual, participants receive evaluations of clinical symptoms, emotional perception, theory of mind, and attributional bias.&#xD;
There are three main themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3) integration: checking it out. After each theme of the intervention, participants will fill out a satisfaction survey.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>Arm BA</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>&quot;A&quot; means SCIT program, and &quot;B&quot; means treatment as usual. Arm BA will first receive treatment as usual, then a 60-minutes manual-guide SCIT session each week for 20 times.&#xD;
At the first week, before and after the SCIT session, participants receive evaluations of clinical symptoms, emotional perception, theory of mind, and attributional bias.&#xD;
There are three main themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3) integration: checking it out. After each theme of the intervention, participants will fill out a satisfaction survey.</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>Social Cognition and Interaction Training (SCIT)</intervention_name>
    <description>The social cognition and interaction training (SCIT) is a manual-guide group intervention that can apply to people with serious mental illness. There have been evidences showing that the SCIT could improve emotional perception, theory of mind, attribution bias, and social relationship.</description>
    <arm_group_label>Arm AB</arm_group_label>
    <arm_group_label>Arm BA</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  diagnosis of mental illness&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  acute hospitalization within the past two months&#xD;
&#xD;
          -  other diseases that may affect cognitive function, such as intellectual disability,&#xD;
             substance abuse&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>20 Years</minimum_age>
    <maximum_age>65 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <overall_official>
    <last_name>Yi chia Liu</last_name>
    <role>Principal Investigator</role>
    <affiliation>National Cheng-Kung University Hospital</affiliation>
  </overall_official>
  <overall_contact>
    <last_name>Wei-Yun Hsu</last_name>
    <phone>886-6-2353535</phone>
    <phone_ext>4365</phone_ext>
    <email>t76054024@gs.ncku.edu.tw</email>
  </overall_contact>
  <location>
    <facility>
      <name>National Cheng Kung University Hospital</name>
      <address>
        <city>Tainan</city>
        <zip>704</zip>
        <country>Taiwan</country>
      </address>
    </facility>
    <contact>
      <last_name>Wei-Yun Hsu</last_name>
      <phone>886-6-2353535</phone>
      <phone_ext>4365</phone_ext>
      <email>t76054024@gs.ncku.edu.tw</email>
    </contact>
  </location>
  <location_countries>
    <country>Taiwan</country>
  </location_countries>
  <verification_date>May 2020</verification_date>
  <study_first_submitted>May 21, 2020</study_first_submitted>
  <study_first_submitted_qc>June 10, 2020</study_first_submitted_qc>
  <study_first_posted type="Actual">June 11, 2020</study_first_posted>
  <last_update_submitted>June 10, 2020</last_update_submitted>
  <last_update_submitted_qc>June 10, 2020</last_update_submitted_qc>
  <last_update_posted type="Actual">June 11, 2020</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <keyword>social cognition</keyword>
  <keyword>Social cognition and interaction training</keyword>
  <keyword>mental illness</keyword>
  <condition_browse>
    <!-- CAUTION:  The following MeSH terms are assigned with an imperfect algorithm            -->
    <mesh_term>Mental Disorders</mesh_term>
  </condition_browse>
  <patient_data>
    <sharing_ipd>No</sharing_ipd>
  </patient_data>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT04428996
org study id: B-BR-108-066
nct id: NCT04428996
lead sponsor: 
has dmc: No
is fda regulated drug: No
is fda regulated device: No
Social cognition dysfunction (including emotional perception, theory of mind, and attribution
      bias) is a common dysfunction in serious mental illness, which may influence their life roles
      and daily functions. The social cognition and interaction training (SCIT) is a manual-guide
      group intervention that can apply to people with serious mental illness.Thus this study aims
      to conduct SCIT groups in Taiwan to investigate its feasibility and effectiveness.

      This study will include 30 clients. Investigators will randomly allot participants into two
      group, and conduct a crossover design. The experimental group will receive a 60-minutes
      manual-guide SCIT session each week for 20 times, which will be leaded by 2 licensed
      occupational therapists. After the intervention, investigators will analyze demographic data
      and compare the difference between experimental group and control group on the social
      cognition performance.
Social cognition dysfunction (including emotional perception, theory of mind, and attribution
      bias) is a common dysfunction in serious mental illness, which may influence their life roles
      and daily functions. The social cognition and interaction training (SCIT) is a manual-guide
      group intervention that can apply to people with serious mental illness. There have been
      evidences showing that the SCIT could improve emotional perception, theory of mind,
      attribution bias, and social relationship. However, there are no SCIT studies in Taiwan yet.
      Thus this study aims to conduct SCIT groups in Taiwan to investigate its feasibility and
      effectiveness.

      This study will include 30 clients from a day care ward and community rehabilitation center,
      excluding clients with acute onset, brain injury, intellectual disability and substance
      abuse. The investigators will randomly allot participants into two group, and conduct a
      crossover design. Before and after the intervention protocol, both group receive evaluations
      of clinical symptoms, emotional perception, theory of mind, and attributional bias. The
      experimental group will receive a 60-minutes manual-guide SCIT session each week for 20
      times, which will be leaded by 2 licensed occupational therapists. There are three main
      themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3)
      integration: checking it out. After each theme of the intervention, participants will fill
      out a satisfaction survey. And a senior occupational therapist will observe the group and
      rate the fidelity of the group. The control group will receive treatment as usual.

      After the intervention, the investigators will analyze demographic data and compare the
      difference between experimental group and control group on the social cognition performance.
allocation: Randomized
intervention model: Crossover Assignment
primary purpose: Treatment
masking: None (Open Label)
measure: Test of Theory of mind #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: Includes language theory of mind and non-verbal theory of mind. Language theory of mind mainly measures the ability of cognitive components and emotional components. There are ten major questions, each of which contains four sub-questions. The first sub-question is a memory question, which must be answered correctly. The scores of the other three sub-questions are calculated. The full score of the language assignment is 30 points. There are ten questions in total, and the full score for non-verbal theory of mind is 20 points. About the internal consistency reliability, the language part is .91 and the non-verbal part is .93. About the test-retest reliability, the language part is .89 and the non-verbal part is .88.
measure: Ambiguous Intentions Hostility Questionnaire #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: This is a measure of the attribution of the subject to the event, including 5 negative situations. Ask the subject to imagine that they are the protagonist in the situation. The first question responds to others' reasons for themselves. The second question is 6 The Likert scale (1 is absolutely not, 6 is absolutely yes) whether responding to others is intentional, the third question is to respond to your own with a 5 point Likert scale (1 is completely not, 5 is very angry) The degree of anger, the fourth question is also the degree of blaming others with a 5-point Likert scale (1 is not at all, 5 is absolutely), and finally asked the subjects to respond to the actions they will take; first Questions and the fifth question are evaluated by the evaluator based on his response. This is a tool with good reliability and validity, including internal consistency (alpha = .84 ~ .86) and inter-tester reliability (ICCs = .91 ~ .99).
measure: Attributional Style Questionnaire #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: This is a questionnaire to assess the social cognition of the subjects, including the theory of mind, cognitive schema and verbal memory. There are 10 scenarios, each of which contains 3 yes-or-no questions, and one question is about degree of judgment. The scoring method is scoring according to three sub-items. The content of the response of the subjects is compared with the norm. If it is lower than two standard deviations, the degree is disabled.
measure: Diagnostic Analysis of Nonverbal Accuracy, Taiwanese version #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: The DANVA-2-TW, a parallel version of the Diagnostic Analysis of Non-verbal Accuracy 2 (Nowicki and Duke, 1994), is a validated (Pan et al., 2009; Tseng et al., 2013), culturally suitable (Tseng et al., 2012) nonverbal measure for Han Chinese, considering that race and culture may considerably affect the accuracy of judging nonverbal emotions (Jack et al., 2012; Wickline et al., 2009). The DANVA-2-TW comprises 60 facial photographs and 60 voice clips representing specific emotions and intensities, including happy, sad, angry, fearful, and neutral stimuli.
measure: Self-Reported Graphic version of Personal and Social Performance rating scale #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: The PSP scale was developed for assessing patients' function by mental health professions . The rater can assess one global score as well as sub-scores of the four domains: socially useful activities, personal and social relationships, self-care, and disturbing and aggressive behaviors. The PSP showed good interrater (ICC = 0.87) and test-retest (ICCs > 0.90) reliability (Patrick et al., 2009) and adequate validity (Cronbach aloha = 0.76) (Kawata & Revicki, 2008). As many studies showed that people with schizophrenia have greater impairment in processing speed and verbal memory than visual spatial-perception memory, a graphic version of PSP (SRG-PSP) was developed. The results of this SRG-PSP were significantly correlated to those of their corresponding criteria on the PSP. The SRG-PSP total score ranges from 12 to 51, and the higher the score, the better social performance.
measure: Trail Making Test #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: This is a test to assess visual attention, task conversion, processing speed and cognitive flexibility. Contains two parts. Part A is a number from 1-25, and the subjects must connect the numbers in order. Part B contains 12 numbers and 12 letters. The subjects must connect the numbers and the zodiac in sequence (1-Mouse-2-Bull-3 ...). The scoring method is the individual seconds to complete these two tasks. According to the research by Wang et al. In 2018, this tool has good reliability (ICC> .75).
measure: Brief Psychiatric Rating Scale
time frame: baseline
description: The BPRS (Overall & Gorham, 1962) is one of the most frequently used instruments for evaluating psychopathology in people with schizophrenia. Its psychometric properties in terms of reliability, validity and sensitivity have been extensively examined (Leucht et al., 2005). It measures psychiatric symptoms such as depression, anxiety, hallucinations and unusual behavior. Each symptom is rated 1 (not present) to 7 (extremely severe).
measure: Brief Symptom Rating Scale-50 #Change from baseline at 20 weeks and 40 weeks
time frame: baseline, 20th week, 40th week
description: Lee, Lee, Yen, Lin, and Lue (1990) revised the Symptom Checklist-90-R scale (Derogatis, Rickels, & Rock, 1976) to develop BSRS-50. The scale contains 50 symptom descriptions and can be summarized into 10 concepts, including physicalization, compulsiveness, interpersonal sensitivity, depression, anxiety, hostility, fear, suspiciousness, psychosis and additional symptoms. Subjects report the degree of distress they feel based on each symptom. Each item is rated 0-4 points, 0 points: no, 4 points: very powerful. Research supports BRSR-50 with good psychometric characteristics
arm group label: Arm AB
arm group type: Experimental
description: "A" means SCIT program, and "B" means treatment as usual. Arm AB will receive a 60-minutes manual-guide SCIT session each week for 20 times first, then receive treatment as usual.
Before the SCIT session, after the SCIT session and after 20 weeks treatment as usual, participants receive evaluations of clinical symptoms, emotional perception, theory of mind, and attributional bias.
There are three main themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3) integration: checking it out. After each theme of the intervention, participants will fill out a satisfaction survey.
arm group label: Arm BA
arm group type: Experimental
description: "A" means SCIT program, and "B" means treatment as usual. Arm BA will first receive treatment as usual, then a 60-minutes manual-guide SCIT session each week for 20 times.
At the first week, before and after the SCIT session, participants receive evaluations of clinical symptoms, emotional perception, theory of mind, and attributional bias.
There are three main themes of the SCIT: 1) introduction and emotion, 2) figuring out situation and 3) integration: checking it out. After each theme of the intervention, participants will fill out a satisfaction survey.
intervention type: Behavioral
intervention name: Social Cognition and Interaction Training (SCIT)
description: The social cognition and interaction training (SCIT) is a manual-guide group intervention that can apply to people with serious mental illness. There have been evidences showing that the SCIT could improve emotional perception, theory of mind, attribution bias, and social relationship.
arm group label: Arm AB
arm group label: Arm BA
criteria: 
gender: All
minimum age: 20 Years
maximum age: 65 Years
healthy volunteers: No
last name: Yi chia Liu
role: Principal Investigator
affiliation: National Cheng-Kung University Hospital
last name: Wei-Yun Hsu
phone: 886-6-2353535
phone ext: 4365
email: t76054024@gs.ncku.edu.tw
facility: 
contact: 
country: Taiwan
responsible party type: Sponsor
mesh term: Mental Disorders
sharing ipd: No