<clinical_study>
  <!-- This xml conforms to an XML Schema at:
    https://clinicaltrials.gov/ct2/html/images/info/public.xsd -->
  <required_header>
    <download_date>ClinicalTrials.gov processed this data on September 20, 2023</download_date>
    <link_text>Link to the current ClinicalTrials.gov record.</link_text>
    <url>https://clinicaltrials.gov/ct2/show/NCT04410458</url>
  </required_header>
  <id_info>
    <org_study_id>Recruit Blood Donors via SMS 2</org_study_id>
    <nct_id>NCT04410458</nct_id>
  </id_info>
  <brief_title>Recruit Blood Donors Via SMS During Epidemic of COVID-19 （Repeat Trial）</brief_title>
  <official_title>Recruit Blood Donors Via SMS With Different Contents During Epidemic of COVID-19（Repeat Trial）</official_title>
  <sponsors>
    <lead_sponsor>
      <agency>Guangzhou Blood Center</agency>
      <agency_class>Other</agency_class>
    </lead_sponsor>
  </sponsors>
  <source>Guangzhou Blood Center</source>
  <oversight_info>
    <is_fda_regulated_drug>No</is_fda_regulated_drug>
    <is_fda_regulated_device>No</is_fda_regulated_device>
  </oversight_info>
  <brief_summary>
    <textblock>
      The fight against the spread of the 2019-nCoV epidemic has achieved some success in China,&#xD;
      but the epidemic is far from over. A key factor making the epidemic under control in China is&#xD;
      the government's call for social distance, which has led to few people going out for&#xD;
      donation. As a result, the number of blood donors on the streets has been continuing to&#xD;
      decline. The first urgent recruitment of blood donors had been implemented during the period&#xD;
      from 30 April to 10 May via emergency recruitment SMS . This repeat trial has been designed&#xD;
      to further confirm the results from the the first recruitment by comparing which information&#xD;
      extraction frameworks would be more sensitive to blood donors in emergency situations.&#xD;
    </textblock>
  </brief_summary>
  <detailed_description>
    <textblock>
      Researches has showed that that the information extraction and processing in emergency was&#xD;
      different from the normal situation. To understand what information the blood donors are more&#xD;
      sensitive to in an environment that may pose a potential threat to themselves, the first&#xD;
      urgent recruitment of blood donors had been implemented during the period from 30 April to 10&#xD;
      . This interventional study is the repeat trail of the first trail. The same with first&#xD;
      trail, eligible blood donors in Guangzhou Blood Center has been randomly divided into four&#xD;
      groups according to their sociological variables, their interval since last blood donation ,&#xD;
      their history donation times and the location of their last blood donation. Three groups of&#xD;
      donors has been randomly selected as interventional groups, and will receive three kindly of&#xD;
      emergency blood donor recruitment SMS respectively. The placebo group donors will only&#xD;
      receive a thank-you SMS. One recruitment SMS will emphasize what blood services will do to&#xD;
      ensure the safety of blood donors during their donation in 2019-nCoV epidemic,one will shows&#xD;
      information about a loss-based framework, while the third one will show information about a&#xD;
      benefit-based framework .&#xD;
    </textblock>
  </detailed_description>
  <overall_status>Unknown status</overall_status>
  <last_known_status>Enrolling by invitation</last_known_status>
  <start_date type="Anticipated">May 31, 2020</start_date>
  <completion_date type="Anticipated">June 12, 2020</completion_date>
  <primary_completion_date type="Anticipated">May 31, 2020</primary_completion_date>
  <phase>N/A</phase>
  <study_type>Interventional</study_type>
  <has_expanded_access>No</has_expanded_access>
  <study_design_info>
    <allocation>Randomized</allocation>
    <intervention_model>Parallel Assignment</intervention_model>
    <primary_purpose>Health Services Research</primary_purpose>
    <masking>None (Open Label)</masking>
  </study_design_info>
  <primary_outcome>
    <measure>Blood donation rate</measure>
    <time_frame>12 days</time_frame>
    <description>Blood donation rate of donors in each group</description>
  </primary_outcome>
  <number_of_arms>4</number_of_arms>
  <enrollment type="Anticipated">506517</enrollment>
  <condition>Blood Donation</condition>
  <arm_group>
    <arm_group_label>SMS with safty ensurance</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>SMS content in this group will be about what blood services will do to ensure the safety of blood donors' life saving donation during 2019-nCoV epidemic.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>SMS with saving life call-1</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>SMS content in this group will be about calling the blood donors to a life saving donation.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>SMS with saving life call-2</arm_group_label>
    <arm_group_type>Experimental</arm_group_type>
    <description>SMS content in this group will be about calling the blood donors to a life saving donation.</description>
  </arm_group>
  <arm_group>
    <arm_group_label>SMS with thank-you note</arm_group_label>
    <arm_group_type>Placebo Comparator</arm_group_type>
    <description>SMS content in this group will be thank-you note for their previous donation(s) .</description>
  </arm_group>
  <intervention>
    <intervention_type>Behavioral</intervention_type>
    <intervention_name>blood donation SMS</intervention_name>
    <description>The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.</description>
    <arm_group_label>SMS with safty ensurance</arm_group_label>
    <arm_group_label>SMS with saving life call-1</arm_group_label>
    <arm_group_label>SMS with saving life call-2</arm_group_label>
    <arm_group_label>SMS with thank-you note</arm_group_label>
  </intervention>
  <eligibility>
    <criteria>
      <textblock>
        Inclusion Criteria:&#xD;
&#xD;
          -  Blood donors whose last turning up were between November 31, 2016 to November 31, 2019&#xD;
&#xD;
        Exclusion Criteria:&#xD;
&#xD;
          -  Blood donors who were deferral by blood screening result and other situations. Blood&#xD;
             donors who have indicated that they would not accept urgent recruitment.&#xD;
      </textblock>
    </criteria>
    <gender>All</gender>
    <minimum_age>18 Years</minimum_age>
    <maximum_age>60 Years</maximum_age>
    <healthy_volunteers>No</healthy_volunteers>
  </eligibility>
  <location>
    <facility>
      <name>Guangzhou Blood Center</name>
      <address>
        <city>Guangzhou</city>
        <state>Guangdong</state>
        <zip>510095</zip>
        <country>China</country>
      </address>
    </facility>
  </location>
  <location_countries>
    <country>China</country>
  </location_countries>
  <verification_date>May 2020</verification_date>
  <study_first_submitted>May 29, 2020</study_first_submitted>
  <study_first_submitted_qc>May 29, 2020</study_first_submitted_qc>
  <study_first_posted type="Actual">June 1, 2020</study_first_posted>
  <last_update_submitted>May 29, 2020</last_update_submitted>
  <last_update_submitted_qc>May 29, 2020</last_update_submitted_qc>
  <last_update_posted type="Actual">June 1, 2020</last_update_posted>
  <responsible_party>
    <responsible_party_type>Sponsor</responsible_party_type>
  </responsible_party>
  <!-- Results have not yet been posted for this study                                          -->
</clinical_study>


download date: ClinicalTrials.gov processed this data on September 20, 2023
link text: Link to the current ClinicalTrials.gov record.
url: https://clinicaltrials.gov/ct2/show/NCT04410458
org study id: Recruit Blood Donors via SMS 2
nct id: NCT04410458
lead sponsor: 
is fda regulated drug: No
is fda regulated device: No
The fight against the spread of the 2019-nCoV epidemic has achieved some success in China,
      but the epidemic is far from over. A key factor making the epidemic under control in China is
      the government's call for social distance, which has led to few people going out for
      donation. As a result, the number of blood donors on the streets has been continuing to
      decline. The first urgent recruitment of blood donors had been implemented during the period
      from 30 April to 10 May via emergency recruitment SMS . This repeat trial has been designed
      to further confirm the results from the the first recruitment by comparing which information
      extraction frameworks would be more sensitive to blood donors in emergency situations.
Researches has showed that that the information extraction and processing in emergency was
      different from the normal situation. To understand what information the blood donors are more
      sensitive to in an environment that may pose a potential threat to themselves, the first
      urgent recruitment of blood donors had been implemented during the period from 30 April to 10
      . This interventional study is the repeat trail of the first trail. The same with first
      trail, eligible blood donors in Guangzhou Blood Center has been randomly divided into four
      groups according to their sociological variables, their interval since last blood donation ,
      their history donation times and the location of their last blood donation. Three groups of
      donors has been randomly selected as interventional groups, and will receive three kindly of
      emergency blood donor recruitment SMS respectively. The placebo group donors will only
      receive a thank-you SMS. One recruitment SMS will emphasize what blood services will do to
      ensure the safety of blood donors during their donation in 2019-nCoV epidemic,one will shows
      information about a loss-based framework, while the third one will show information about a
      benefit-based framework .
allocation: Randomized
intervention model: Parallel Assignment
primary purpose: Health Services Research
masking: None (Open Label)
measure: Blood donation rate
time frame: 12 days
description: Blood donation rate of donors in each group
arm group label: SMS with safty ensurance
arm group type: Experimental
description: SMS content in this group will be about what blood services will do to ensure the safety of blood donors' life saving donation during 2019-nCoV epidemic.
arm group label: SMS with saving life call-1
arm group type: Experimental
description: SMS content in this group will be about calling the blood donors to a life saving donation.
arm group label: SMS with saving life call-2
arm group type: Experimental
description: SMS content in this group will be about calling the blood donors to a life saving donation.
arm group label: SMS with thank-you note
arm group type: Placebo Comparator
description: SMS content in this group will be thank-you note for their previous donation(s) .
intervention type: Behavioral
intervention name: blood donation SMS
description: The literature shows that the information extraction and processing in emergency is different from the normal situation. To find the most effective emergency recruitment method during an outbreak, we intervened with a well-balanced group of donors by presenting different emergency recruitment text messages.
arm group label: SMS with safty ensurance
arm group label: SMS with saving life call-1
arm group label: SMS with saving life call-2
arm group label: SMS with thank-you note
criteria: 
gender: All
minimum age: 18 Years
maximum age: 60 Years
healthy volunteers: No
facility: 
country: China
responsible party type: Sponsor